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Critical appraisal of “impact of a primary care-based mobile health intervention to ‘sit less and move more’ on HbA1c, blood pressure, and other clinical outcomes in office employees with type 2 diabetes” 对“以初级保健为基础的移动健康干预‘少坐多动’对2型糖尿病办公室员工的HbA1c、血压和其他临床结果的影响”进行了批判性评估。
IF 2.3 4区 医学 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2026-02-01 DOI: 10.1016/j.pcd.2025.11.002
Himanshu Shekhar, Parth Aphale, Shashank Dokania
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引用次数: 0
Efficacy of synchronized diabetes monitoring system in patients with type 2 diabetes: Preliminary results of a pilot, randomized clinical trial 同步糖尿病监测系统对2型糖尿病患者的疗效:一项试点、随机临床试验的初步结果
IF 2.3 4区 医学 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2026-02-01 DOI: 10.1016/j.pcd.2025.11.005
Mustafa Kahraman , Ummu Mutlu , Hasan Ediz Ozbek , Elif Beyza Boz , Ramazan Cakmak , Serkan Kurt , Hatice Vildan Dudukcu , Huseyin Yildiz , Mehmet Ali Erturk , Gokhan Ozogur , Hatice Nizam Ozogur , Muhammed Ali Aydin , Nizamettin Aydin , Sukru Ozturk , Kubilay Karsidag , Ilhan Satman , Mehmet Akif Karan

Aim

The purpose of this study is to evaluate the applicability and efficacy of the Synchronized Diabetes Monitoring System (SDMs), which consists of a smart cap attached to insulin pens with recording, alarm, alert, and reminder functions, and software that operates via Bluetooth, in patients with type 2 diabetes on insulin treatment.

Methods

The system consists of a smart mobile apparatus mounted on an insulin pen and automatically recording the dose and time of the administered insulin, an application developed for mobile phones that can read blood glucose results from the glucometer, and a website.

Results

The system has been tested in a 6-month pilot cohort of SDMs group (n = 23, 44 % female, age: 50.1 ± 13 years, duration: 12.2 ± 9.2 years) in a transparent, controlled, and single-center pilot trial, showing promising results. The results were compared to the control group (n = 23, age: 54 ± 9.3 years, 52 % female, duration: 13.8 ± 7.4 years). In the third month, we found that they had better glycemic control, as indicated by a decrease in fasting blood glucose (from 147 to 114 mg/dL, p = 0.024) and HbA1c levels (from 8.5 % to 7.2 %, p = 0.003). Additionally, improvements were achieved in physical function, role limitation, and physical and mental health domains of SF-36 survey in patients using the system.

Conclusion

The preliminary results from this pilot study suggest that the synchronized diabetes monitoring system have the potential to improve glycemic control and increase health satisfaction in insulin-treated patients with type 2 diabetes.
目的:本研究的目的是评估同步糖尿病监测系统(SDMs)在2型糖尿病患者胰岛素治疗中的适用性和有效性。该系统由一个连接在具有记录、报警、警报和提醒功能的胰岛素笔上的智能帽和通过蓝牙操作的软件组成。方法:该系统由安装在胰岛素笔上的智能移动设备、可自动记录给药胰岛素的剂量和时间、为手机开发的可读取血糖仪血糖结果的应用程序和网站组成。结果:该系统在为期6个月的SDMs组(n = 23,44 %女性,年龄:50.1 ± 13岁,持续时间:12.2 ± 9.2岁)的透明、对照、单中心先导试验中进行了测试,显示出令人满意的结果。结果与对照组(n = 23例,年龄:54 ± 9.3岁,52 %为女性,病程:13.8 ± 7.4岁)进行比较。在第三个月,我们发现他们有更好的血糖控制,空腹血糖(从147降至114 mg/dL, p = 0.024)和HbA1c水平(从8.5 %降至7.2 %,p = 0.003)。此外,使用该系统的患者在SF-36调查的身体功能、角色限制和身心健康领域均取得了改善。结论:本中试研究的初步结果表明,糖尿病同步监测系统具有改善胰岛素治疗的2型糖尿病患者血糖控制和提高健康满意度的潜力。
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引用次数: 0
Patient-reported experience, patient-reported outcome and overall satisfaction with care: What matters most to people with diabetes? 患者报告的经历、患者报告的结果和总体护理满意度:对糖尿病患者最重要的是什么?
IF 2.3 4区 医学 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2026-02-01 DOI: 10.1016/j.pcd.2025.10.004
Nizar Alsubahi , Wim Groot , Ahmed Ali Alzahrani , Milena Pavlova
<div><h3>Background</h3><div>Diabetes management has become a critical healthcare challenge globally, emphasizing the need for patient-centered care to improve the quality of services and enhance treatment outcomes. Patient experiences, perceived outcomes, and satisfaction are crucial to optimizing healthcare delivery, but each reflects different aspects of care. Understanding how these measures relate to each other is key to improving healthcare evaluation and avoiding dependence on a single metric. This study examines how patient-centered care (PCC) is associated with patient-reported experience measures (PREMs) and patient-reported outcome measures (PROMs), as well as overall patient satisfaction (PS) among people with diabetes.</div></div><div><h3>Method</h3><div>This study uses cross-sectional quantitative data from a structured, interviewer-administered questionnaire in 47 primary healthcare centers in Jeddah, Saudi Arabia, and is reported in accordance with the CROSS (Consensus-Based Checklist for Reporting of Survey Studies) guidelines. A total of 594 people with diabetes were recruited using random sampling from these centers. PCC was measured using the PCC-36 instrument. PREMs and PROMs were assessed using items adapted from the Swedish National Diabetes Register, while PS was measured using a validated single-item scale. Each was evaluated as a continuous measure, where higher scores indicate more positive experiences, outcomes, or satisfaction. A regression analysis was conducted to investigate the interrelationships between PREMs, PROMs, and PS and control for the effect of relevant sociodemographic and health-related characteristics. The data analysis was carried out using STATA 18.</div></div><div><h3>Result</h3><div>The results of the study indicated that PCC had a significant positive relationship with PROMs (β = 0.316, p < 0.01), PREMs (β = 0.063, p < 0.05), and PS (β = 0.689, p < 0.01). A strong residual correlation was observed between PREMs and PROMs (β = 0.734, p < 0.01), while the residual association between PREMs and PS was minimal (β = 0.063, p < 0.05). Emotional support was significantly associated with PROMs (β = 0.170, p < 0.01) and PREMs (β = 0.078, p < 0.01) but had a negative association with PS (β = −0.084, p < 0.1). Family and friends’ involvement was a significant predictor of PROMs (β = 0.193, p < 0.01), PREMs (β = 0.125, p < 0.01), and PS (β = 0.082, p < 0.05). Physical comfort was positively associated with PS (β = 0.128, p < 0.01) but negatively associated with PROMs (β = −0.143, p < 0.01) and PREMs (β = −0.056, p < 0.05). Access to care is significantly associated with PS (β = 0.176, p < 0.01).</div></div><div><h3>Conclusion</h3><div>This study highlights the crucial role of PCC, showing that higher levels of PCC are associated with more positive patient experiences, health outcomes, and satisfaction among people with diabetes. Key PCC factors include emotional s
背景:糖尿病管理已成为全球医疗保健的一个关键挑战,强调需要以患者为中心的护理,以提高服务质量和提高治疗效果。患者体验、感知结果和满意度对于优化医疗保健服务至关重要,但每个都反映了护理的不同方面。了解这些指标如何相互关联是改进医疗保健评估和避免依赖单一指标的关键。本研究探讨了以患者为中心的护理(PCC)如何与患者报告的体验测量(PREMs)和患者报告的结果测量(PROMs)以及糖尿病患者的总体患者满意度(PS)相关联。方法:本研究使用来自沙特阿拉伯吉达47个初级卫生保健中心的结构化访谈问卷的横断面定量数据,并根据CROSS(报告调查研究的共识清单)指南进行报告。研究人员从这些中心随机抽取了594名糖尿病患者。PCC采用PCC-36仪测定。PREMs和prom采用瑞典国家糖尿病登记册中的项目进行评估,而PS采用经过验证的单项目量表进行测量。每一项都是作为连续的衡量标准来评估的,分数越高表明越积极的经历、结果或满意度。对PREMs、PROMs和PS之间的相互关系进行回归分析,并对相关社会人口统计学和健康相关特征的影响进行控制。使用STATA 18进行数据分析。结果:研究结果表明PCC与PROMs呈显著正相关(β = 0.316, p )。结论:本研究强调了PCC的重要作用,表明高水平的PCC与糖尿病患者更积极的患者体验、健康结果和满意度相关。关键的PCC因素包括情感支持、家人和朋友的参与以及获得护理。因此,以患者为中心的实践必须是糖尿病护理质量改进策略的组成部分。虽然PCC的变化在很大程度上解释了糖尿病患者报告的测量和满意度的变化,但忽略或未观察到的因素的变化驱动了这些测量。这些发现强调了进一步调查PS、PROMs和PREMs之间的性质和关系以及它们在根据患者优先级定制护理中的应用的重要性。
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引用次数: 0
Comment on: Cognitive impairment is associated with poor diabetic foot ulcer outcomes 点评:认知障碍与糖尿病足溃疡预后不良相关。
IF 2.3 4区 医学 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2026-02-01 DOI: 10.1016/j.pcd.2025.11.003
Shixuan Guo, Juan Shu
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引用次数: 0
High prevalence of undiagnosed obstructive sleep apnoea in older adults with suboptimally-controlled type 2 diabetes and comorbid insomnia 未确诊的阻塞性睡眠呼吸暂停在控制不佳的2型糖尿病和合并症失眠的老年人中高发。
IF 2.3 4区 医学 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2026-02-01 DOI: 10.1016/j.pcd.2025.12.003
Chun Kwan O , Rachel NY Chan , Ka Pang Chan , Hongjiang Wu , Fanny MF Lam , Hester HC Lee , Elaine YK Chow , Andrea OY Luk , Ronald CW Ma , Yun Kwok Wing , Juliana CN Chan , Alice PS Kong

Background

We aimed to explore the prevalence of and clinical factors that identify obstructive sleep apnoea (OSA) in older adults with suboptimally-controlled type 2 diabetes (T2D) and comorbid insomnia.

Methods

In this cross-sectional analysis, participants had age≥ 60 years, HbA1c7.5–10 % and comorbid insomnia [insomnia severity index (ISI)> 14] with no prior history of OSA. All participants had home sleep apnoea testing done to measure apnoea-hypopnea index (AHI) and completed questionnaires including self-reporting of habitual snoring (≥3 nights/week), Four-Variable Screening Tool (FVST) comprising sex, body mass index (BMI), blood pressure and frequency of snoring, and excessive daytime sleepiness (EDS) [Epworth Sleepiness Scale (ESS) score ≥ 10]. Mild, moderate, and severe OSA were defined by AHI 5 to < 15, ≥ 15 to < 30, and ≥ 30 events/hour respectively.

Results

Among 93 participants(mean age: 68.3 ± 4.8 years, 46 % men, BMI:24.8 ± 3.7 kg/m2), 87 % had OSA (43 % moderate-to-severe OSA) and 41.8 % had EDS. A diagnosis of OSA was associated with BMI[odd ratio(OR)1.233(95 %CI:1.015–1.498),p = 0.035], habitual snoring[8.107(2.192–29.977), p = 0.002], and FVST[1.386(1.132–1.698), p = 0.002]. The cut-off value of FVST≥ 5 or ESS≥ 10 had 100 % sensitivity and 20.8 (9.8–31.7)% specificity to detect moderate-to-severe OSA.

Conclusions

Older adults with suboptimally-controlled T2D and comorbid insomnia had high prevalence of undiagnosed OSA with FVST and EDS as potentially useful screening tools.
背景:我们的目的是探讨阻塞性睡眠呼吸暂停(OSA)在老年控制欠佳的2型糖尿病(T2D)和合并症失眠患者中的患病率和临床因素。方法:在本横断面分析中,参与者年龄≥ 60岁,hba1c7.5 - %,共病性失眠[失眠严重程度指数(ISI)> 14],无OSA病史。所有参与者在家中进行睡眠呼吸暂停测试,测量呼吸暂停低通气指数(AHI),并完成问卷调查,包括习惯性打鼾(≥3晚/周)的自我报告,四变量筛选工具(FVST),包括性别、体重指数(BMI)、血压和打鼾频率,以及白天过度嗜睡(EDS) [Epworth嗜睡量表(ESS)评分≥ 10]。轻微、中等和严重的阻塞性睡眠呼吸暂停综合症是由AHI 5结果:在93名参与者(平均年龄:68.3 ± 4.8岁,46 %男性,体重指数:24.8 ±3.7  kg / m2), 87年 %阻塞性睡眠呼吸暂停综合症(43 %是严重阻塞性睡眠呼吸暂停综合症)和41.8 % EDS。OSA的诊断与BMI[奇比(OR)1.233(95 %CI:1.015-1.498),p = 0.035]、习惯性打鼾[8.107(2.192-29.977),p = 0.002]、FVST[1.386(1.132-1.698), p = 0.002]相关。FVST≥ 5或ESS≥ 10的临界值检测中重度OSA的敏感性为100 %,特异性为20.8(9.8-31.7)%。结论:T2D控制不佳并伴有合并症失眠的老年人未确诊OSA的患病率较高,FVST和EDS可作为潜在有用的筛查工具。
{"title":"High prevalence of undiagnosed obstructive sleep apnoea in older adults with suboptimally-controlled type 2 diabetes and comorbid insomnia","authors":"Chun Kwan O ,&nbsp;Rachel NY Chan ,&nbsp;Ka Pang Chan ,&nbsp;Hongjiang Wu ,&nbsp;Fanny MF Lam ,&nbsp;Hester HC Lee ,&nbsp;Elaine YK Chow ,&nbsp;Andrea OY Luk ,&nbsp;Ronald CW Ma ,&nbsp;Yun Kwok Wing ,&nbsp;Juliana CN Chan ,&nbsp;Alice PS Kong","doi":"10.1016/j.pcd.2025.12.003","DOIUrl":"10.1016/j.pcd.2025.12.003","url":null,"abstract":"<div><h3>Background</h3><div>We aimed to explore the prevalence of and clinical factors that identify obstructive sleep apnoea (OSA) in older adults with suboptimally-controlled type 2 diabetes (T2D) and comorbid insomnia.</div></div><div><h3>Methods</h3><div>In this cross-sectional analysis, participants had age≥ 60 years, HbA<sub>1c</sub>7.5–10 % and comorbid insomnia [insomnia severity index (ISI)&gt; 14] with no prior history of OSA. All participants had home sleep apnoea testing done to measure apnoea-hypopnea index (AHI) and completed questionnaires including self-reporting of habitual snoring (≥3 nights/week), Four-Variable Screening Tool (FVST) comprising sex, body mass index (BMI), blood pressure and frequency of snoring, and excessive daytime sleepiness (EDS) [Epworth Sleepiness Scale (ESS) score ≥ 10]. Mild, moderate, and severe OSA were defined by AHI 5 to &lt; 15, ≥ 15 to &lt; 30, and ≥ 30 events/hour respectively.</div></div><div><h3>Results</h3><div>Among 93 participants(mean age: 68.3 ± 4.8 years, 46 % men, BMI:24.8 ± 3.7 kg/m<sup>2</sup>), 87 % had OSA (43 % moderate-to-severe OSA) and 41.8 % had EDS. A diagnosis of OSA was associated with BMI[odd ratio(OR)1.233(95 %CI:1.015–1.498),p = 0.035], habitual snoring[8.107(2.192–29.977), <em>p</em> = 0.002], and FVST[1.386(1.132–1.698), <em>p</em> = 0.002]. The cut-off value of FVST≥ 5 or ESS≥ 10 had 100 % sensitivity and 20.8 (9.8–31.7)% specificity to detect moderate-to-severe OSA.</div></div><div><h3>Conclusions</h3><div>Older adults with suboptimally-controlled T2D and comorbid insomnia had high prevalence of undiagnosed OSA with FVST and EDS as potentially useful screening tools.</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Pages 80-87"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145852112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial Board and Aims & Scopes 编辑委员会和目标与范围
IF 2.3 4区 医学 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-11-20 DOI: 10.1016/S1751-9918(25)00211-6
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引用次数: 0
Evolution of Diabetes Mellitus Care in Hong Kong Public Primary Care Setting: Changes after 10-year Implementation of Risk Assessment and Management Program in Diabetes Mellitus (RAMP-DM) 香港公营基层医疗机构糖尿病护理的演变:实施糖尿病风险评估及管理计划(RAMP-DM) 10年后的变化
IF 2.3 4区 医学 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-10-11 DOI: 10.1016/j.pcd.2025.10.002
Fangfang Jiao, Lapkin Chiang, Yim Chu Li, Catherine Xiaorui Chen

Aims

This study aims to evaluate the changes in clinical profiles, complications, and treatment modalities of people with diabetes after a decade of implementing the multidisciplinary Risk Assessment and Management Program in DM (RAMP-DM).

Methods

A two-phase cross-sectional study was conducted to examine the evolution of care for people with diabetes in 13 public primary care clinics from 1 August 2008 to 31 July 2009 and 1 August 2019 to 31 July 2020.

Results

The average systolic blood pressure (SBP) improved from 131.66±16.89 to 126.88±12.54 mmHg (P<0.001). Hemoglobin A1c (HbA1c) and low-density lipoprotein concentration (LDL-C) improved from 7.47±1.4 to 6.88±1.00% (P<0.001) and 3.09±0.85 to 2.01±0.68 mmol/L (P<0.001), respectively. However, the percentage of patients with ischemic heart disease (IHD) rose from 7.73% to 10.47% (P<0.001), and stroke increased from 8.22% to 12.44% (P<0.001) over the decade.

Conclusions

This is the first study to demonstrate the improvement of clinical parameters and treatment modalities of diabetes care in a public primary care setting over a decade. The increasing prevalence of IHD and stroke may be related to the aging population and the decreasing trend of all-cause mortality among people with diabetes.
目的:本研究旨在评估在实施糖尿病多学科风险评估和管理计划(RAMP-DM)十年后,糖尿病患者的临床概况、并发症和治疗方式的变化。方法:采用两阶段横断面研究,研究2008年8月1日至2009年7月31日和2019年8月1日至2020年7月31日期间13家公立初级保健诊所对糖尿病患者护理的演变。结果:平均收缩压(SBP)从131.66±16.89改善到126.88±12.54 mmHg(结论:这是第一个证明十年来公共初级保健机构糖尿病护理临床参数和治疗方式改善的研究。IHD和卒中患病率的上升可能与人口老龄化和糖尿病患者全因死亡率的下降趋势有关。
{"title":"Evolution of Diabetes Mellitus Care in Hong Kong Public Primary Care Setting: Changes after 10-year Implementation of Risk Assessment and Management Program in Diabetes Mellitus (RAMP-DM)","authors":"Fangfang Jiao,&nbsp;Lapkin Chiang,&nbsp;Yim Chu Li,&nbsp;Catherine Xiaorui Chen","doi":"10.1016/j.pcd.2025.10.002","DOIUrl":"10.1016/j.pcd.2025.10.002","url":null,"abstract":"<div><h3>Aims</h3><div>This study aims to evaluate the changes in clinical profiles, complications, and treatment modalities of people with diabetes after a decade of implementing the multidisciplinary Risk Assessment and Management Program in DM (RAMP-DM).</div></div><div><h3>Methods</h3><div>A two-phase cross-sectional study was conducted to examine the evolution of care for people with diabetes in 13 public primary care clinics from 1 August 2008 to 31 July 2009 and 1 August 2019 to 31 July 2020.</div></div><div><h3>Results</h3><div>The average systolic blood pressure (SBP) improved from 131.66±16.89 to 126.88±12.54 mmHg (P&lt;0.001). Hemoglobin A1c (HbA1c) and low-density lipoprotein concentration (LDL-C) improved from 7.47±1.4 to 6.88±1.00% (P&lt;0.001) and 3.09±0.85 to 2.01±0.68 mmol/L (P&lt;0.001), respectively. However, the percentage of patients with ischemic heart disease (IHD) rose from 7.73% to 10.47% (P&lt;0.001), and stroke increased from 8.22% to 12.44% (P&lt;0.001) over the decade.</div></div><div><h3>Conclusions</h3><div>This is the first study to demonstrate the improvement of clinical parameters and treatment modalities of diabetes care in a public primary care setting over a decade. The increasing prevalence of IHD and stroke may be related to the aging population and the decreasing trend of all-cause mortality among people with diabetes.</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"19 6","pages":"Pages 671-677"},"PeriodicalIF":2.3,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding insulin dose deviations in people with type 2 diabetes receiving telemonitoring 了解接受远程监测的2型糖尿病患者的胰岛素剂量偏差。
IF 2.3 4区 医学 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-10-07 DOI: 10.1016/j.pcd.2025.10.001
Jannie Toft Damsgaard Nørlev , Thomas Kronborg , Morten Hasselstrøm Jensen , Peter Vestergaard , Stine Hangaard

Aims

Although telemonitoring has emerged as a strategy to overcome barriers related to poor adherence, insulin dose deviations remain common. Yet, the reason remains unclear. This study investigated the reasons for dose deviations in people with insulin-treated type 2 diabetes (T2D) receiving telemonitoring.

Methods

Data were provided from 331 participants with insulin-treated T2D (DiaMonT, NCT 04981808). Participants were either telemonitored using a continuous glucose monitor (CGM), a connected insulin pen, and an activity watch or treated according to standard of care, using blinded devices. Reasons for dose deviations were categorized, and descriptive statistics were used to summarize the findings.

Results

A total of 24 distinct reasons for insulin dose deviations were reported. These were grouped into: (1) actual deviations (40.1 %; n = 148) (e.g., limited understanding of T2D and access to CGM data), (2) justified deviations (40.7 %; n = 150) (e.g., illness and use of a non-connected pen), and (3) device-related deviations (19.2 %; n = 71) (e.g., technical issues).

Conclusions

This study highlights the need for a nuanced interpretation of adherence data and suggests that telemonitoring should engage patients in treatment discussions and support education in diabetes self-management. These insights are key to maximizing the benefits of telemonitoring while avoiding misinterpretation or over-intervention.
目的:尽管远程监测已成为克服不良依从性障碍的一种策略,但胰岛素剂量偏差仍然很常见。然而,原因尚不清楚。本研究调查了接受远程监护的胰岛素治疗2型糖尿病(T2D)患者剂量偏差的原因。方法:数据来自331名胰岛素治疗的t2dm患者(DiaMonT, NCT04981808)。参与者要么使用连续血糖监测仪(CGM)、连接胰岛素笔和活动表进行远程监测,要么使用盲法设备进行标准护理。对剂量偏差的原因进行分类,并采用描述性统计对结果进行总结。结果:共报道了24种不同的胰岛素剂量偏差原因。这些都是分为:(1)实际偏差(40.1 %;n = 148)(例如,有限的理解T2D和CGM数据),(2)合理的偏差(40.7 %;n = 150)(例如,疾病和使用non-connected笔),和(3)device-related偏差(19.2 %;n = 71)(例如,技术问题)。结论:本研究强调需要对依从性数据进行细致入微的解释,并建议远程监测应使患者参与治疗讨论,并支持糖尿病自我管理教育。这些见解对于最大限度地发挥远程监控的优势,同时避免误解或过度干预至关重要。
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引用次数: 0
The effect of online health management on type 2 diabetes mellitus: A systematic review and meta-analysis 在线健康管理对2型糖尿病的影响:系统回顾和荟萃分析
IF 2.3 4区 医学 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-10-04 DOI: 10.1016/j.pcd.2025.08.010
Yiwei Qiu , Yao Tang , Yixuan Li , Li Cheng , Xu Wang , Baofeng Du , Ruhai Bai

Background

Online health management has been implemented to improve glycemic control in patients with type 2 diabetes mellitus (T2DM). This study aims to evaluate the effectiveness of online health management interventions in managing T2DM through a systematic review and meta-analysis.

Methods

A comprehensive search was conducted in six databases—PubMed, Web of Science, Cochrane Library, Embase, China National Knowledge Infrastructure, and Wanfang Data—from January 1, 2010, to September 1, 2024. Eligible studies included randomized controlled trials (RCTs) involving adults (≥ 18 years) diagnosed with T2DM. Two independent reviewers screened the studies and assessed the risk of bias. Meta-analyses were performed using Review Manager 5.4 (Cochrane Collaboration). The primary outcomes included glycated hemoglobin (HbA1c), fasting blood glucose (FBG), and postprandial blood glucose (PBG).

Results

Out of 6283 records screened, 44 RCTs involving 27,178 T2DM patients were included (16,972 in the intervention group and 10,206 in the control group). Pooled results showed that online health management interventions significantly improved HbA1c, FBG, PBG, systolic blood pressure, diastolic blood pressure, and waist circumference. Improvements were also observed in dietary behavior, physical activity, and self-efficacy. However, no significant effects were found on body weight, body mass index, or lipid metabolism parameters, including total cholesterol, triglycerides, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol. Subgroup analyses indicated that interventions delivered by physicians, those targeting individuals aged ≥ 60 years, and those using digital coaching for less than six months were more effective in glycemic control.

Conclusion

Online health management interventions may effectively support glycemic and blood pressure control and self-management in T2DM patients. Nevertheless, additional research with larger sample sizes and more extended follow-up periods is justified due to the substantial heterogeneity and limitations across the included studies.
背景:在线健康管理已被用于改善2型糖尿病(T2DM)患者的血糖控制。本研究旨在通过系统回顾和荟萃分析来评估在线健康管理干预在管理2型糖尿病方面的有效性。方法:从2010年1月1日至2024年9月1日,对pubmed、Web of Science、Cochrane Library、Embase、中国知识基础设施和万方数据6个数据库进行综合检索。符合条件的研究包括诊断为T2DM的成年人(≥18岁)的随机对照试验(RCTs)。两名独立审稿人筛选了这些研究并评估了偏倚风险。meta分析采用Review Manager 5.4 (Cochrane Collaboration)进行。主要结局包括糖化血红蛋白(HbA1c)、空腹血糖(FBG)和餐后血糖(PBG)。结果:在筛选的6283份记录中,纳入44项随机对照试验,涉及27,178例T2DM患者(干预组16,972例,对照组10,206例)。综合结果显示,在线健康管理干预显著改善了HbA1c、FBG、PBG、收缩压、舒张压和腰围。在饮食行为、体育活动和自我效能方面也有改善。然而,没有发现对体重、体重指数或脂质代谢参数(包括总胆固醇、甘油三酯、高密度脂蛋白胆固醇和低密度脂蛋白胆固醇)有显著影响。亚组分析表明,由医生提供的干预措施,针对年龄≥ 60岁的个体,以及使用数字指导少于6个月的干预措施在血糖控制方面更有效。结论:在线健康管理干预可有效支持T2DM患者血糖、血压控制和自我管理。然而,由于纳入研究的异质性和局限性,需要进行更大样本量和更长的随访期的额外研究。
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引用次数: 0
Microvascular disease burden and macrovascular outcomes in type 2 diabetes: Risk calculator in Taiwan 台湾2型糖尿病的微血管疾病负担与大血管预后:风险计算器。
IF 2.3 4区 医学 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-10-01 DOI: 10.1016/j.pcd.2025.09.004
Chih-Yuan Wang , Jung-Fu Chen , Shih-Te Tu , Chun-Chuan Lee , Horng-Yih Ou
The growing prevalence of type 2 diabetes mellitus (T2DM) poses a significant challenge to healthcare systems globally. Microvascular diseases, including diabetic kidney disease, retinopathy, and neuropathy, are frequent complications of T2DM and may signal an increased risk of macrovascular diseases, such as stroke and myocardial infarction. This study, based on prior findings from a nationwide cohort in Taiwan demonstrated that individuals with two or more macrovascular complications had elevated risks of cardiovascular events and mortality over a median follow-up of 3.3 years. Building on this, the current study develops a practical risk calculator for predicting 3-year cardiovascular risk. Shared pathogenic mechanisms, such as vascular injury, endothelial dysfunction, and autonomic neuropathy, may suggest these associations. In response, we developed a Risk Engine Calculator that incorporates the number of microvascular diseases, elevated HbA1c, systolic blood pressure, LDL cholesterol, and insulin use to estimate 3-year cardiovascular risk in patients with T2DM without established macrovascular complications. Patients are stratified into low, moderate, or high risk categories to guide clinical decision-making. While the calculator is practical and evidence-based, limitations include its additive design, potential simplification of risk relationships, and relatively short follow-up period. Overall, this study underscores the importance of integrating microvascular diseases burden into cardiovascular risk assessment and provides a user-friendly tool to support precision medicine in diabetes management.
2型糖尿病(T2DM)的日益流行对全球卫生保健系统提出了重大挑战。微血管疾病,包括糖尿病肾病、视网膜病变和神经病变,是T2DM的常见并发症,可能预示着大血管疾病(如中风和心肌梗死)的风险增加。本研究基于台湾一项全国性队列研究的先前发现,表明在中位随访3.3年期间,患有两种或两种以上大血管并发症的个体心血管事件和死亡率风险升高。在此基础上,本研究开发了一种实用的风险计算器,用于预测3年心血管风险。共同的致病机制,如血管损伤、内皮功能障碍和自主神经病变,可能提示这些关联。作为回应,我们开发了一个风险引擎计算器,将微血管疾病的数量、HbA1c升高、收缩压、低密度脂蛋白胆固醇和胰岛素的使用纳入其中,以估计无大血管并发症的T2DM患者3年心血管风险。患者被分为低、中、高风险三类,以指导临床决策。尽管该计算器具有实用性和循证性,但其局限性包括其累加式设计、可能简化风险关系以及相对较短的随访期。总之,本研究强调了将微血管疾病负担纳入心血管风险评估的重要性,并提供了一个用户友好的工具来支持糖尿病管理中的精准医学。
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Primary Care Diabetes
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