Pub Date : 2021-01-11DOI: 10.23736/S0392-0488.20.06851-0
C. Micalizzi, R. Russo, E. Cozzani, A. Guadagno, M. Paudice, A. Parodi
{"title":"Lichen planus pigmentosus inversus concomitant with two internal malignancies. A paraneoplastic cutaneous sign?","authors":"C. Micalizzi, R. Russo, E. Cozzani, A. Guadagno, M. Paudice, A. Parodi","doi":"10.23736/S0392-0488.20.06851-0","DOIUrl":"https://doi.org/10.23736/S0392-0488.20.06851-0","url":null,"abstract":"","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2021-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73248197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-11DOI: 10.23736/S0392-0488.20.06602-X
A. Sechi, F. Tartari, A. Patrizi, A. Virdi, M. Leuzzi, I. Neri
{"title":"Severe hidradenitis suppurativa in a patient affected by Hermansky-Pudlak syndrome type 9: possible shared pathogenetic aspects.","authors":"A. Sechi, F. Tartari, A. Patrizi, A. Virdi, M. Leuzzi, I. Neri","doi":"10.23736/S0392-0488.20.06602-X","DOIUrl":"https://doi.org/10.23736/S0392-0488.20.06602-X","url":null,"abstract":"","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2021-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72626912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.23736/S0392-0488.20.06773-5
F. Bellinato, M. Maurelli, P. Gisondi, Maria D Lleo'Fernandez, G. Girolomoni
BACKGROUND Infectious urethritis are classified in N. gonorrhoeae (NG) urethritis and nongonococcal urethritis, caused commonly by C. trachomatis (CT) or M. genitalium (MG) in Western Europe. The primary objective of the study is to evaluate the association between the clinical profile and the pathogens. Secondly, to assess the prevalence of co-infections. METHODS The clinical profile of urethritis in men caused by NG, CT and MG confirmed by nucleic acid amplification test (NAAT) on first void urine has been retrospectively collected. The clinical profiles comprised the assessment of dysuria and/or discharge and the clinicaldermoscopic examination of the genitalia. Serological tests for syphilis and HIV were also performed. RESULTS A total of 101 episodes of NAAT confirmed NG, CT or MG urethritis were identified. The prevalence for each pathogen was 50.60%, 33.73% and 15.66%, respectively. Co-infections were observed in few cases (4 MG+CT, 1 NG+CT, 1 NG+MG), with M. hominis, U. urealitycum and U. parvum positivity found concomitantly in 7-8% cases. The median age of patients was 33 years. Dysuria was reported in 88% cases (95% NG, 79% CT, 78% MG urethritis). Urethral discharge was found in 86% of cases, including purulent discharge in 61% (98% NG, 70% MG) and transparent in 25% (64% CT). Dysuria and purulent discharge were observed in 95% NG, 54% MG and 29% CT cases, whereas dysuria and transparent discharge were observed in 50% CT, 23% MG and in none of NG cases (p<0.01). Balanitis/meatitis was observed in 24% of cases, genital warts in 12% and proctalgia in 4%. CONCLUSIONS NAAT is crucial for defining urethritis etiology. Dysuria is the most common symptom. Gonococcal urethritis present with purulent discharge, whereas transparent discharge is associated with non-gonococcal pathogens. Co-infections are rare. Clinical exam may detect other infectious diseases, in particular genital warts.
{"title":"Clinical profile and co-infections of urethritis in males.","authors":"F. Bellinato, M. Maurelli, P. Gisondi, Maria D Lleo'Fernandez, G. Girolomoni","doi":"10.23736/S0392-0488.20.06773-5","DOIUrl":"https://doi.org/10.23736/S0392-0488.20.06773-5","url":null,"abstract":"BACKGROUND\u0000Infectious urethritis are classified in N. gonorrhoeae (NG) urethritis and nongonococcal urethritis, caused commonly by C. trachomatis (CT) or M. genitalium (MG) in Western Europe. The primary objective of the study is to evaluate the association between the clinical profile and the pathogens. Secondly, to assess the prevalence of co-infections.\u0000\u0000\u0000METHODS\u0000The clinical profile of urethritis in men caused by NG, CT and MG confirmed by nucleic acid amplification test (NAAT) on first void urine has been retrospectively collected. The clinical profiles comprised the assessment of dysuria and/or discharge and the clinicaldermoscopic examination of the genitalia. Serological tests for syphilis and HIV were also performed.\u0000\u0000\u0000RESULTS\u0000A total of 101 episodes of NAAT confirmed NG, CT or MG urethritis were identified. The prevalence for each pathogen was 50.60%, 33.73% and 15.66%, respectively. Co-infections were observed in few cases (4 MG+CT, 1 NG+CT, 1 NG+MG), with M. hominis, U. urealitycum and U. parvum positivity found concomitantly in 7-8% cases. The median age of patients was 33 years. Dysuria was reported in 88% cases (95% NG, 79% CT, 78% MG urethritis). Urethral discharge was found in 86% of cases, including purulent discharge in 61% (98% NG, 70% MG) and transparent in 25% (64% CT). Dysuria and purulent discharge were observed in 95% NG, 54% MG and 29% CT cases, whereas dysuria and transparent discharge were observed in 50% CT, 23% MG and in none of NG cases (p<0.01). Balanitis/meatitis was observed in 24% of cases, genital warts in 12% and proctalgia in 4%.\u0000\u0000\u0000CONCLUSIONS\u0000NAAT is crucial for defining urethritis etiology. Dysuria is the most common symptom. Gonococcal urethritis present with purulent discharge, whereas transparent discharge is associated with non-gonococcal pathogens. Co-infections are rare. Clinical exam may detect other infectious diseases, in particular genital warts.","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77466339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.23736/S0392-0488.20.06809-1
G. Dal Bello, C. Colato, G. Girolomoni
{"title":"Exfoliative cheilitis as a manifestation of factitial cheilitis in a young man.","authors":"G. Dal Bello, C. Colato, G. Girolomoni","doi":"10.23736/S0392-0488.20.06809-1","DOIUrl":"https://doi.org/10.23736/S0392-0488.20.06809-1","url":null,"abstract":"","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81986346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.23736/S0392-0488.20.06776-0
E. Nagore, R. Moro
INTRODUCTION Surgery is the main treatment for cutaneous melanoma including the primary melanoma as well as lymph node metastases. The recommended margins have changed over time. Similarly, indications for sentinel lymph node biopsy and complete lymph node dissection are constantly evolving as long as knowledge on the biological behavior of melanomas increases. EVIDENCE ACQUISITION The current guidelines and the most relevant literature was reviewed to provide an update on the existing recommendations for surgical management of melanoma. EVIDENCE SYNTHESIS Wide excision margins are evidenced-based but not for all situations. Melanoma in situ requires 0.5-1 cm with increasing evidence for 1 cm particularly those presenting on the head and in the setting of chronic sun damage. Invasive melanomas need 1-2 cm margins, 2 cm for tumors thicker than 2 mm and some large tumors with >1-2 mm thickness and with a lentiginous growth pattern. Lentigo maligna, subungual melanoma, and acral lentiginous melanoma require surgical techniques with complete circumferential peripheral margin assessment. Sentinel lymph node biopsy provides relevant information for melanoma staging. Therefore, it is consistently recommended for melanomas >1-4 mm and highly recommended for melanomas >4 mm, >0.8-1.0 mm or ≤0.8 mm with additional risk factors. Complete lymph node dissection has high morbidity and no impact on survival and is restricted to regional control for clinically detected metastasis. CONCLUSIONS Although the trend is to reduce progressively the recommended surgical margins, further evidence is needed to clarify its role in patients' survival. Sentinel lymph node biopsy is important for establishing a prognosis especially upon considering adjuvant therapy; complete lymph node dissection is only relevant for regional disease control.
{"title":"Surgical procedures in melanoma in 2020: recommended deep and lateral margins, indications for sentinel lymph node biopsy, and complete lymph node dissection.","authors":"E. Nagore, R. Moro","doi":"10.23736/S0392-0488.20.06776-0","DOIUrl":"https://doi.org/10.23736/S0392-0488.20.06776-0","url":null,"abstract":"INTRODUCTION\u0000Surgery is the main treatment for cutaneous melanoma including the primary melanoma as well as lymph node metastases. The recommended margins have changed over time. Similarly, indications for sentinel lymph node biopsy and complete lymph node dissection are constantly evolving as long as knowledge on the biological behavior of melanomas increases.\u0000\u0000\u0000EVIDENCE ACQUISITION\u0000The current guidelines and the most relevant literature was reviewed to provide an update on the existing recommendations for surgical management of melanoma.\u0000\u0000\u0000EVIDENCE SYNTHESIS\u0000Wide excision margins are evidenced-based but not for all situations. Melanoma in situ requires 0.5-1 cm with increasing evidence for 1 cm particularly those presenting on the head and in the setting of chronic sun damage. Invasive melanomas need 1-2 cm margins, 2 cm for tumors thicker than 2 mm and some large tumors with >1-2 mm thickness and with a lentiginous growth pattern. Lentigo maligna, subungual melanoma, and acral lentiginous melanoma require surgical techniques with complete circumferential peripheral margin assessment. Sentinel lymph node biopsy provides relevant information for melanoma staging. Therefore, it is consistently recommended for melanomas >1-4 mm and highly recommended for melanomas >4 mm, >0.8-1.0 mm or ≤0.8 mm with additional risk factors. Complete lymph node dissection has high morbidity and no impact on survival and is restricted to regional control for clinically detected metastasis.\u0000\u0000\u0000CONCLUSIONS\u0000Although the trend is to reduce progressively the recommended surgical margins, further evidence is needed to clarify its role in patients' survival. Sentinel lymph node biopsy is important for establishing a prognosis especially upon considering adjuvant therapy; complete lymph node dissection is only relevant for regional disease control.","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76294306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.23736/S0392-0488.20.06819-4
D. Geat, B. Tonin, C. Colato, G. Girolomoni
{"title":"A case of porokeratosis with predominant follicular involvement.","authors":"D. Geat, B. Tonin, C. Colato, G. Girolomoni","doi":"10.23736/S0392-0488.20.06819-4","DOIUrl":"https://doi.org/10.23736/S0392-0488.20.06819-4","url":null,"abstract":"","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85055654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.23736/S0392-0488.20.06774-7
M. Domínguez-Santas, C. Moya‐Martínez, D. Fernández-Nieto, J. Jimenez‐Cauhe, A. Suárez-Valle, B. Díaz-Guimaraens
{"title":"Purpura annularis telangiectodes of Majocchi triggered by iodinated radiocontrast medium.","authors":"M. Domínguez-Santas, C. Moya‐Martínez, D. Fernández-Nieto, J. Jimenez‐Cauhe, A. Suárez-Valle, B. Díaz-Guimaraens","doi":"10.23736/S0392-0488.20.06774-7","DOIUrl":"https://doi.org/10.23736/S0392-0488.20.06774-7","url":null,"abstract":"","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85308456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.23736/S0392-0488.20.06834-0
A. Di Altobrando, M. Leuzzi, D. Abbenante, A. Patrizi, F. Bardazzi
{"title":"Does ethnic psoriasis exist?","authors":"A. Di Altobrando, M. Leuzzi, D. Abbenante, A. Patrizi, F. Bardazzi","doi":"10.23736/S0392-0488.20.06834-0","DOIUrl":"https://doi.org/10.23736/S0392-0488.20.06834-0","url":null,"abstract":"","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74043205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.23736/S0392-0488.20.06856-X
A. Sechi, A. Guglielmo, A. Patrizi, Clara Bertuzzi, I. Neri, A. Pileri
{"title":"Atopic dermatitis and mycosis fungoides in a child: an overlooked association.","authors":"A. Sechi, A. Guglielmo, A. Patrizi, Clara Bertuzzi, I. Neri, A. Pileri","doi":"10.23736/S0392-0488.20.06856-X","DOIUrl":"https://doi.org/10.23736/S0392-0488.20.06856-X","url":null,"abstract":"","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78158312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.23736/S0392-0488.20.06798-X
V. Manfreda, L. Cerroni, M. Teoli, L. Bianchi, A. Giunta
{"title":"Connective tissue nevus in Marfan syndrome successfully treated with intralesional steroid injections.","authors":"V. Manfreda, L. Cerroni, M. Teoli, L. Bianchi, A. Giunta","doi":"10.23736/S0392-0488.20.06798-X","DOIUrl":"https://doi.org/10.23736/S0392-0488.20.06798-X","url":null,"abstract":"","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76370795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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