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Ethics of Mathematical Modeling in Public Health: The Case of Medical Male Circumcision for HIV Prevention in Africa. 公共卫生中的数学建模伦理:以非洲男性包皮环切术预防艾滋病毒为例。
IF 1.4 3区 哲学 Q2 ETHICS Pub Date : 2024-10-14 eCollection Date: 2024-11-01 DOI: 10.1093/phe/phae009
Stuart Rennie, Sara Levintow, Adam Gilbertson, Winnie Kavulani Luseno

Mathematical modelling has played an increasingly prominent role in public health responses, for example by offering estimates of how infectious disease incidence over time may be affected by the adoption of certain policies and interventions. In this paper, we call for greater research and reflection into the ethics of mathematical modeling in public health. First, we present some promising ways of framing the ethics of mathematical modeling that have been offered in the very few publications specifically devoted to this subject. Second, to draw out some issues that have not yet been sufficiently considered, we bring in the case of mathematical modeling in voluntary medical male circumcision (VMMC) initiatives for HIV prevention in Africa. We argue that greater attention should be paid to ethical considerations in mathematical modeling, particularly as its use is becoming more widespread and its potential impacts are becoming greater in the 'big data' era, as witnessed during the COVID-19 pandemic.

数学模型在公共卫生对策中发挥着日益突出的作用,例如,它可以估计采取某些政策和干预措施对传染病发病率的长期影响。在本文中,我们呼吁对公共卫生数学建模的伦理进行更多的研究和反思。首先,我们提出了一些有希望的方法来构建数学建模的伦理,这些方法已经在极少数专门致力于这一主题的出版物中提供。第二,为了找出一些尚未得到充分考虑的问题,我们引入了非洲预防艾滋病毒的自愿医疗男性包皮环切(VMMC)倡议中的数学模型。我们认为,应更多地关注数学建模中的道德因素,特别是在新冠肺炎大流行期间,数学建模的使用越来越广泛,其潜在影响在“大数据”时代变得越来越大。
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引用次数: 0
Ethical Dimensions of Population-Based Lung Cancer Screening in Canada: Key Informant Qualitative Description Study. 加拿大全民肺癌筛查的伦理问题:关键信息提供者定性描述研究》。
IF 1.4 3区 哲学 Q2 ETHICS Pub Date : 2024-08-29 eCollection Date: 2024-11-01 DOI: 10.1093/phe/phae008
Manisha Pahwa, Julia Abelson, Paul A Demers, Lisa Schwartz, Katrina Shen, Meredith Vanstone

Normative issues associated with the design and implementation of population-based lung cancer screening policies are underexamined. This study was an exposition of the ethical justification for screening and potential ethical issues and their solutions in Canadian jurisdictions. A qualitative description study was conducted. Key informants, defined as policymakers, scientists and clinicians who develop and implement lung cancer screening policies in Canada, were purposively sampled and interviewed using a semi-structured guide informed by population-based disease screening principles and ethical issues in cancer screening. Interview data were analyzed using qualitative content analysis. Fifteen key informants from seven provinces were interviewed. Virtually all justified screening by beneficence, describing that population benefits outweigh individual harms if high-risk people are screened in organized programs according to disease screening principles. Equity of screening access, stigma and lung cancer primary prevention were other ethical issues identified. Key informants prioritized beneficence over concerns for group-level justice issues when making decisions about whether to implement screening policies. This prioritization, though slight, may impede the implementation of screening policies in a way that effectively addresses justice issues, a goal likely to require justice theory and critical interpretation of disease screening principles.

与以人群为基础的肺癌筛查政策的设计和实施相关的规范性问题尚未得到充分审查。本研究是对加拿大司法管辖区筛选和潜在伦理问题及其解决方案的伦理理由的阐述。进行了定性描述研究。主要信息提供者(定义为在加拿大制定和实施肺癌筛查政策的决策者、科学家和临床医生)使用基于人群的疾病筛查原则和癌症筛查中的伦理问题的半结构化指南进行了有目的的抽样和访谈。访谈资料采用定性内容分析法进行分析。采访了来自7个省的15名关键线人。事实上,所有的筛查都是通过慈善来证明的,描述了如果高风险人群根据疾病筛查原则在有组织的项目中进行筛查,那么人群的益处大于个人的危害。筛查机会公平、污名化和肺癌一级预防是确定的其他伦理问题。在决定是否实施筛查政策时,关键举报人优先考虑的是慈善,而不是群体层面的正义问题。这种优先次序虽然轻微,但可能会阻碍筛查政策的实施,从而有效地解决司法问题,这一目标可能需要司法理论和对疾病筛查原则的批判性解释。
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引用次数: 0
From Self-Management to Shared-Management: A Relational Approach for Equitable Chronic Care 从自我管理到共享管理:公平慢性病护理的关系方法
IF 2.1 3区 哲学 Q2 ETHICS Pub Date : 2024-08-22 DOI: 10.1093/phe/phae007
Francisca Stutzin Donoso
Life with chronic disease and chronic care is hard and people who live in disadvantage may lack the freedom to prioritise their care because of increased competing demands. This paper proposes that shifting the goals of chronic care from self-management support to a shared-management approach can help improve wellbeing and health outcomes across social groups. This work draws on a qualitative exploration of the lived experience of chronic disease and an applied ethical analysis of the reproduction of disadvantages within chronic care. The qualitative results further specify respectful and collaborative patient-healthcare professional relationships; autonomy-supportive interventions; and continuity of care to face the complexity of chronicity in a phenomenological sense—a paradoxical experience of long duration that comprises the disease’s presence in the absence of its manifestation. The ethical analysis draws on performativity; autonomy and decision-making; and responsibility, which constitute the theoretical foundation for shared-management. This approach contributes to advance current normative thinking for health justice and outlines practical steps for its clinical implementation in the delivery of chronic care.
患有慢性疾病和长期护理的人生活艰辛,而生活在弱势群体中的人可能会因为更多相互竞争的需求而无法自由地优先考虑他们的护理。本文提出,将慢性病护理的目标从自我管理支持转向共同管理方法,有助于改善不同社会群体的福祉和健康状况。这项工作借鉴了对慢性病生活体验的定性探索,以及对慢性病护理中的不利因素再现进行的应用伦理分析。定性结果进一步明确了患者与医疗保健专业人员之间相互尊重、相互协作的关系;支持自主性的干预措施;以及从现象学意义上面对慢性病复杂性的连续性护理--一种由疾病存在而疾病不存在的长期矛盾体验。伦理分析借鉴了表演性、自主和决策以及责任,这些构成了共同管理的理论基础。这种方法有助于推进当前的健康正义规范思想,并概述了在提供慢性病护理的临床实施中的实际步骤。
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引用次数: 0
The Application of Australian Rights Protections to the Use of Hepatitis C Notification Data to Engage People ‘Lost to Follow Up’ 澳大利亚权利保护措施在使用丙型肝炎通知数据吸引 "失去随访 "者方面的应用
IF 2.1 3区 哲学 Q2 ETHICS Pub Date : 2024-05-18 DOI: 10.1093/phe/phae006
Freya Saich, Shelley Walker, Margaret Hellard, Mark Stoové, Kate Seear
Hepatitis C is a global public health threat, affecting 56 million people worldwide. The World Health Organization has committed to eliminating hepatitis C by 2030. Although new treatments have revolutionised the treatment and care of people with hepatitis C, treatment uptake has slowed in recent years, drawing attention to the need for innovative approaches to reach elimination targets. One approach involves using existing notifiable disease data to contact people previously diagnosed with hepatitis C. Within these disease surveillance systems, however, competing tensions exist, including protecting individual rights to privacy and autonomy, and broader public health goals. We explore these issues using hepatitis C and Australia’s legislative and regulatory frameworks as a case study. We examine emerging uses of notification data to contact people not yet treated, and describe some of the ethical dilemmas associated with the use and non-use of this data and the protections that exist to preserve individual rights and public health. We reveal weaknesses in rights protections and processes under Australian public health and human rights legislation and argue for consultation with and involvement of affected communities in policy and intervention design before notification data is used to increase hepatitis C treatment coverage.
丙型肝炎是一种全球性的公共健康威胁,影响着全球 5600 万人。世界卫生组织承诺到 2030 年消灭丙型肝炎。虽然新的治疗方法彻底改变了丙型肝炎患者的治疗和护理,但近年来治疗接受率有所放缓,这使人们注意到需要采用创新方法来实现消除丙型肝炎的目标。然而,在这些疾病监测系统中存在着相互竞争的矛盾,包括保护个人隐私和自主权以及更广泛的公共卫生目标。我们以丙型肝炎和澳大利亚的立法与监管框架为案例,探讨了这些问题。我们研究了新出现的使用通知数据来联系尚未接受治疗者的情况,并描述了与使用和不使用这些数据相关的一些道德困境,以及为维护个人权利和公共健康而存在的保护措施。我们揭示了澳大利亚公共卫生和人权立法在权利保护和程序方面的薄弱环节,并主张在使用通知数据提高丙型肝炎治疗覆盖率之前,应与受影响社区进行协商并让其参与政策和干预措施的设计。
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引用次数: 0
Time to Treat the Climate and Nature Crisis as One Indivisible Global Health Emergency. 是时候将气候和自然危机视为一个不可分割的全球健康紧急情况了。
IF 1.4 3区 哲学 Q2 ETHICS Pub Date : 2024-03-23 eCollection Date: 2024-04-01 DOI: 10.1093/phe/phad022
Kamran Abbasi, Parveen Ali, Virginia Barbour, Thomas Benfield, Kirsten Bibbins-Domingo, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Robert Mash, Peush Sahni, Wadeia Mohammad Sharief, Paul Yonga, Chris Zielinski
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引用次数: 0
Psychedelics in PERIL: The Commercial Determinants of Health, Financial Entanglements and Population Health Ethics Psychedelics in PERIL:健康的商业决定因素、金融纠葛与人口健康伦理
IF 2.1 3区 哲学 Q2 ETHICS Pub Date : 2024-03-02 DOI: 10.1093/phe/phae002
Daniel Buchman, Daniel Rosenbaum
The nascent for-profit psychedelic industry has begun to engage in corporate practices like funding scientific research and research programs. There is substantial evidence that such practices from other industries like tobacco, alcohol, pharmaceuticals and food create conflicts of interest and can negatively influence population health. However, in a context of funding pressures, low publicly funded success rates and precarious academic labor, there is limited ethics guidance for researchers working at the intersection of clinical practice and population health as to how they should approach potential financial sponsorship from for-profit entities, such as the psychedelic industry. This article reports on a reflective exercise among a group of clinician scientists working in psychedelic science, where we applied Adams’ (2016) PERIL (Purpose, Extent, Relevant harm, Identifiers, Link) ethical decision-making framework to a fictionalized case of corporate psychedelic financial sponsorship. Our analysis suggests financial relationships with the corporate psychedelic sector may create varying degrees of risk to a research program’s purpose, autonomy and integrity. We argue that the commercial determinants of health provide a useful framework for understanding the ethics of industry-healthcare entanglements and can provide an important population health ethics lens to examine nascent industries such as psychedelics, and work toward potential solutions.
新生的以营利为目的的迷幻药行业已经开始参与企业行为,如资助科学研究和研究项目。有大量证据表明,烟草、酒精、药品和食品等其他行业的此类做法会造成利益冲突,并对人口健康产生负面影响。然而,在资金压力大、公共资助成功率低、学术劳动岌岌可危的背景下,对于从事临床实践与人口健康交叉领域工作的研究人员来说,他们应该如何对待来自迷幻药行业等营利性实体的潜在经济赞助,目前的伦理指导还很有限。本文报告了一组从事迷幻剂科学研究的临床科学家的反思活动,我们将亚当斯(2016 年)的 PERIL(目的、范围、相关危害、标识符、联系)伦理决策框架应用于一个虚构的企业迷幻剂财务赞助案例。我们的分析表明,与企业迷幻药部门的财务关系可能会给研究项目的目的、自主性和完整性带来不同程度的风险。我们认为,健康的商业决定因素为理解产业与医疗保健之间的伦理纠葛提供了一个有用的框架,可以为研究迷幻药等新兴产业提供一个重要的人口健康伦理视角,并努力寻找潜在的解决方案。
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引用次数: 0
The Liberalism of Fear and Public Health Ethics 恐惧的自由主义与公共卫生伦理
IF 2.1 3区 哲学 Q2 ETHICS Pub Date : 2024-02-27 DOI: 10.1093/phe/phae001
Alvin Chen
This article argues that the liberalism of fear provides a useful theoretical framework for public health ethics in two fronts. First, it helps reconcile the tension between public health interventions and liberal politics. Second, it reinforces the existing justifications for public health interventions in liberal political culture. The article discusses this in the context of political emotions in the COVID-19 pandemic. Fear plays a central role in the experiences of pandemic politics, and such fear is extended to the concern that post-pandemic government would normalize emergency politics and threaten the political culture of liberal democracy. The article proposes that the liberalism of fear provides a theoretical solution not only to alleviate such fear, but also to reconcile the long-established tension between liberal politics and public health intervention. This is particularly so if the liberalism of fear’s characteristic of political realism is taken into account. The article makes two points about this, and discusses their pragmatic implications in the case of compulsory vaccination.
本文认为,恐惧自由主义在两个方面为公共卫生伦理提供了有用的理论框架。首先,它有助于调和公共卫生干预与自由主义政治之间的矛盾。其次,它强化了自由主义政治文化中现有的公共卫生干预理由。文章以 COVID-19 大流行中的政治情绪为背景对此进行了讨论。恐惧在大流行病政治经历中扮演着核心角色,这种恐惧延伸到了对大流行病后政府将使应急政治正常化并威胁自由民主政治文化的担忧。文章提出,恐惧的自由主义不仅为减轻这种恐惧提供了理论解决方案,而且还调和了自由主义政治与公共卫生干预之间长期存在的紧张关系。如果考虑到恐惧自由主义的政治现实主义特征,这一点尤为重要。文章就此提出了两个观点,并讨论了它们在强制疫苗接种中的实际意义。
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引用次数: 0
Reciprocity, Fairness and the Financial Burden of Undertaking COVID-19 Hotel Quarantine in Australia. 互惠、公平与澳大利亚 COVID-19 酒店检疫的财政负担。
IF 1.4 3区 哲学 Q2 ETHICS Pub Date : 2023-12-20 eCollection Date: 2024-04-01 DOI: 10.1093/phe/phad027
Kari Pahlman, Jane Williams, Diego S Silva, Louis Taffs, Bridget Haire

In late March 2020 in response to the COVID-19 pandemic, Australia introduced mandatory 14-day supervised quarantine at hotels and other designated facilities for all international arrivals. From July 2020, most states and territories introduced a fixed charge for quarantine of up to $3220 per adult. The introduction of the fee was rationalised on the basis that Australians had been allowed sufficient time to return and there was a need to recover some of the cost associated with administering the program. Drawing on an empirical study of 58 returned Australian citizens and residents quarantined between March 2020 and January 2021, this paper aims to explore how people experienced paying for hotel quarantine, particularly with respect to fairness and relatedly, the principle of reciprocity. Reciprocity requires that the state has an obligation to assist individuals in discharging their duty to comply with public health measures and avoid disproportionate burdens accruing to populations or individuals. Though participants had varying opinions on whether they thought it fair to be charged for their quarantine, for many, the fee constituted a significant burden and source of stress. Given the undertaking of quarantine is primarily for the benefit of the public good, we argue the financial cost imposed on individuals does not meet the demands of reciprocity. It is imperative that future quarantine and isolation arrangements consider seriously the need to minimise burdens of individuals subject to such measures, and that fees do not become a new norm in public health and infectious disease control.

为应对 COVID-19 大流行,澳大利亚于 2020 年 3 月下旬开始在酒店和其他指定设施对所有国际入境者实施为期 14 天的强制监督检疫。从 2020 年 7 月起,大多数州和地区开始对每名成人收取高达 3220 澳元的固定检疫费。收费合理化的依据是,澳大利亚人已经有足够的时间回国,而且有必要收回与管理该计划相关的部分成本。本文通过对 2020 年 3 月至 2021 年 1 月期间被隔离的 58 名回国澳大利亚公民和居民进行实证研究,旨在探讨人们如何体验酒店隔离费用,尤其是在公平性和相关的互惠原则方面。互惠原则要求国家有义务协助个人履行遵守公共卫生措施的义务,避免给人群或个人带来过重的负担。尽管与会者对检疫收费是否公平有不同的看法,但对许多人来说,收费是一个沉重的负担,也是压力的来源。鉴于进行检疫主要是为了公共利益,我们认为强加给个人的经济成本并不符合互惠的要求。当务之急是,未来的检疫和隔离安排应认真考虑尽量减轻受此类措施影响的个人负担的必要性,而且收费不应成为公共卫生和传染病控制的新规范。
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引用次数: 0
How to Design Consent for Health Data Research? An Analysis of Arguments of Solidarity 如何为健康数据研究设计同意书?团结论点分析
IF 2.1 3区 哲学 Q2 ETHICS Pub Date : 2023-12-12 DOI: 10.1093/phe/phad025
Svenja Wiertz
The article discusses the impact different concepts of solidarity can have on debates on models of consent for non-interventional research. It introduces three concepts of solidarity that have been referenced in bioethical debates: a purely descriptive concept, a concept that claims some derivative value for most but not all practices of solidarity, as well as a clearly normative concept where solidarity is tied to justice and taken to ground moral duties. It shows that regarding the rivalling models of study-specific consent, tiered consent and broad consent, the first two concepts can be taken to favour tiered consent while only normative solidarity supports a model of broad consent—or an argument to allow non-interventional research without requiring consent at all. As normative solidarity is tied to considerations of justice, however, the argument appears less straightforward than one might expect: It presupposes that the research contributes to overcoming existing social injustices.
文章讨论了不同的团结概念对非干预性研究同意模式辩论的影响。文章介绍了生物伦理辩论中提到的三种团结概念:一种纯粹描述性的概念,一种声称大多数团结实践(而非所有团结实践)具有某种衍生价值的概念,以及一种明确的规范性概念,在这种概念中,团结与正义联系在一起,并被视为道德义务的基础。它表明,在针对特定研究的同意、分层同意和广泛同意这几种相互对立的模式中,前两种概念都可以被视为有利于分层同意,而只有规范性团结支持广泛同意的模式--或者说支持允许进行非干预性研究而无需征得同意的论点。然而,由于规范团结与正义的考虑相联系,这一论点似乎没有人们想象的那么直截了当:它预先假定研究有助于克服现有的社会不公正现象。
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引用次数: 0
Ageism Without Anticipation-Blindness 没有预期的老龄化--盲目性
IF 2.1 3区 哲学 Q2 ETHICS Pub Date : 2023-12-09 DOI: 10.1093/phe/phad023
Martin Marchman Andersen, Lasse Nielsen
Ageism is the view that it is of greater moral value to allocate health care resources to younger people than to older people. In medical ethics, it is well-known that standard interpretations of distributive principles such as utilitarianism and egalitarianism imply some form of ageism. At times, ethicists argue as if practical complications are the only or main reason for not abiding to ageism. In this article, we argue that inferences to ageism from such distributive principles tend to commit what we call the anticipation-blindness fallacy: A much too narrow focus on life quality benefits of health care treatments inclines us to overlook the importance of life quality benefits of health care safety, that is the mere trust in and expectation of being treated and cared for as one grows old. This is a key omission because health safety has value for a much larger population and for much longer time. Taking health safety into account therefore has important implications as for how ageist we ought to be.
老龄歧视是一种观点,认为将医疗资源分配给年轻人比分配给老年人更具道德价值。在医学伦理学中,众所周知,对功利主义和平等主义等分配原则的标准解释意味着某种形式的年龄歧视。有时,伦理学家会争辩说,似乎实际问题是不遵守年龄歧视的唯一或主要原因。在本文中,我们认为,从这种分配原则推断出老龄歧视,往往会犯我们所说的 "预期盲目 "谬误:过于狭隘地关注医疗保健治疗对生命质量的益处,使我们倾向于忽视医疗保健安全对生命质量益处的重要性,即仅仅是对年老时得到治疗和护理的信任和期望。这是一个关键的疏忽,因为医疗安全对更多的人和更长的时间都有价值。因此,将医疗安全纳入考虑范围对于我们应该如何对待老龄问题具有重要意义。
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引用次数: 0
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Public Health Ethics
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