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OUP accepted manuscript OUP接受稿件
IF 2.1 3区 哲学 Q1 Nursing Pub Date : 2021-01-01 DOI: 10.1093/phe/phab019
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引用次数: 1
OUP accepted manuscript OUP接受稿件
IF 2.1 3区 哲学 Q1 Nursing Pub Date : 2021-01-01 DOI: 10.1093/phe/phab029
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引用次数: 1
OUP accepted manuscript OUP接受稿件
IF 2.1 3区 哲学 Q1 Nursing Pub Date : 2021-01-01 DOI: 10.1093/phe/phab020
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引用次数: 1
OUP accepted manuscript OUP接受稿件
IF 2.1 3区 哲学 Q1 Nursing Pub Date : 2021-01-01 DOI: 10.1093/phe/phab027
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引用次数: 1
An Effort Worth Making: A Qualitative Study of How Swedes Respond to Antibiotic Resistance. 值得付出的努力:瑞典人如何应对抗生素耐药性的定性研究》。
IF 2.1 3区 哲学 Q1 Nursing Pub Date : 2020-12-03 eCollection Date: 2021-04-01 DOI: 10.1093/phe/phaa033
Mirko Ancillotti, Stefan Eriksson, Tove Godskesen, Dan I Andersson, Jessica Nihlén Fahlquist

Due to the alarming rise of antibiotic resistance, medically unwarranted use of antibiotics has assumed new moral significance. In this paper, a thematic content analysis of focus group discussions was conducted to explore lay people's views on the moral challenges posed by antibiotic resistance. The most important finding is that lay people are morally sensitive to the problems entailed by antibiotic resistance. Participants saw the decreasing availability of effective antibiotics as a problem of justice. This involves individual as well as collective moral responsibility. Yet, holding agents responsible for their use of antibiotics involves varying degrees of demandingness. In our discussion, these findings are related to the contemporary ethical debate on antibiotic resistance and two proposals for the preservation of antibiotic effectiveness are compared to and evaluated against participants' views.

由于抗生素耐药性的上升令人担忧,医学上不合理使用抗生素已具有了新的道德意义。本文对焦点小组讨论进行了主题内容分析,以探讨非专业人士对抗生素耐药性带来的道德挑战的看法。最重要的发现是,非专业人士对抗生素耐药性带来的问题具有道德敏感性。参与者认为,有效抗生素供应的减少是一个正义问题。这涉及个人和集体的道德责任。然而,要求代理人对其使用抗生素的行为负责涉及到不同程度的要求。在讨论中,我们将这些发现与当代关于抗生素耐药性的伦理辩论联系起来,并将两种保护抗生素有效性的建议与参与者的观点进行比较和评估。
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引用次数: 0
Willingness to Share yet Maintain Influence: A Cross-Sectional Study on Attitudes in Sweden to the Use of Electronic Health Data. 分享意愿与保持影响力:瑞典对使用电子健康数据态度的横断面研究》。
IF 1.4 3区 哲学 Q2 ETHICS Pub Date : 2020-11-27 eCollection Date: 2021-04-01 DOI: 10.1093/phe/phaa035
Sara Belfrage, Niels Lynöe, Gert Helgesson

We have investigated attitudes towards the use of health data among the Swedish population by analyzing data from a survey answered by 1645 persons. Health data are potentially useful for a variety of purposes. Yet information about health remains sensitive. A balance therefore has to be struck between these opposing considerations in a number of contexts. The attitudes among those whose data is concerned will influence the perceived legitimacy of policies regulating health data use. We aimed to investigate what views are held by the general public, and what aspects matter for the willingness to let one's data be used not only for one's own care but also for other purposes. We found that while there is a broad willingness to let one's data be used, the possibility to influence that use is considered important. The study also indicated that when respondents are required to balance different interests, priority is typically given to compulsory schemes ensuring that data are available where needed, rather than voluntary participation and data protection. The policy implications to be drawn from this are not self-evident, however, since the fact that a majority has a certain attitude does not by itself determine the most adequate policy.

我们通过分析 1645 人回答的调查数据,调查了瑞典民众对使用健康数据的态度。健康数据可用于多种用途。然而,有关健康的信息仍然很敏感。因此,在许多情况下,必须在这些对立的考虑因素之间取得平衡。数据相关者的态度将影响健康数据使用监管政策的合理性。我们的目的是调查公众持有何种观点,以及哪些方面会影响到他们是否愿意让自己的数据不仅用于自身护理,也用于其他目的。我们发现,虽然受访者普遍愿意让自己的数据被用于其他目的,但影响这种使用的可能性也被认为很重要。研究还表明,当受访者需要平衡不同利益时,通常优先考虑的是确保在需要时提供数据的强制性计划,而不是自愿参与和数据保护。不过,从中得出的政策影响并不明显,因为大多数人持某种态度这一事实本身并不能决定最适当的政策。
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引用次数: 0
Return of Results in Population Studies: How Do Participants Perceive Them? 人口研究结果的回归:参与者如何感知它们?
IF 2.1 3区 哲学 Q1 Nursing Pub Date : 2020-11-27 DOI: 10.1093/phe/phaa034
Hélène Nobile, P. Borry, Jennifer Moldenhauer, M. Bergmann
As a cornerstone of public health, epidemiology has lately undergone substantial changes enabled by, among other factors, the use of biobank infrastructures. In biobank-related research, the return of results to participants constitutes an important and complex ethical question. In this study, we qualitatively investigated how individuals perceive the results returned following their participation in cohort studies with biobanks. In our semi-structured interviews with 31 participants of two such German studies, we observed that some participants overestimate the nature of the personal information they will receive from the study. Although this misestimation does not seem to jeopardize the validity of the consent provided at recruitment, it may still represent a threat for participants’ trust in research and thus their long-term commitment, crucial for such studies. We argue that such misestimation may have ethical consequences on the principles guiding the reflection on the return of results in biobank research, i.e. autonomy, beneficence, non-maleficence and reciprocity. We suggest that shifting from the idea of directly benefiting participants through the return of research results could help focusing on benefiting society as a whole, thereby increasing research trustworthiness of population-based studies using biobanks.
流行病学作为公共卫生的基石,由于生物库基础设施的使用等因素,最近发生了重大变化。在生物库相关研究中,将结果反馈给参与者构成了一个重要而复杂的伦理问题。在这项研究中,我们定性地调查了个体如何感知他们参与生物库队列研究后返回的结果。在我们对两项德国研究的31名参与者进行的半结构化访谈中,我们观察到一些参与者高估了他们将从研究中获得的个人信息的性质。虽然这种错误估计似乎不会危及招募时提供的同意的有效性,但它仍然可能威胁到参与者对研究的信任,从而威胁到他们的长期承诺,这对此类研究至关重要。我们认为,这种错误估计可能会对指导对生物样本库研究结果回报进行反思的原则产生伦理后果,即自主、有益、非恶意和互惠。我们建议,从通过研究结果的回报直接使参与者受益的想法转变,可以帮助将重点放在使整个社会受益上,从而提高使用生物银行的基于人群的研究的研究可信度。
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引用次数: 1
Is There an Ethical Upper Limit on Risks to Study Participants? 研究参与者的风险是否存在道德上限?
IF 2.1 3区 哲学 Q1 Nursing Pub Date : 2020-11-03 eCollection Date: 2020-07-01 DOI: 10.1093/phe/phaa028
Nir Eyal

Are some risks to study participants too much, no matter how valuable the study is for society? This article answers in the negative.

不管这项研究对社会有多大价值,对研究参与者来说,是否有些风险太大了?这篇文章的答案是否定的。
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引用次数: 2
The Devils in the DALY: Prevailing Evaluative Assumptions. DALY中的魔鬼:普遍的评估假设。
IF 2.1 3区 哲学 Q1 Nursing Pub Date : 2020-10-29 eCollection Date: 2020-11-01 DOI: 10.1093/phe/phaa030
Carl Tollef Solberg, Preben Sørheim, Karl Erik Müller, Espen Gamlund, Ole Frithjof Norheim, Mathias Barra

In recent years, it has become commonplace among the Global Burden of Disease (GBD) study authors to regard the disability-adjusted life year (DALY) primarily as a descriptive health metric. During the first phase of the GBD (1990-1996), it was widely acknowledged that the DALY had built-in evaluative assumptions. However, from the publication of the 2010 GBD and onwards, two central evaluative practices-time discounting and age-weighting-have been omitted from the DALY model. After this substantial revision, the emerging view now appears to be that the DALY is primarily a descriptive measure. Our aim in this article is to argue that the DALY, despite changes, remains largely evaluative. Our analysis focuses on the understanding of the DALY by comparing the DALY as a measure of disease burden in the two most significant phases of GBD publications, from their beginning (1990-1996) to the most recent releases (2010-2017). We identify numerous assumptions underlying the DALY and group them as descriptive or evaluative. We conclude that while the DALY model arguably has become more descriptive, it remains, by necessity, largely evaluative.

近年来,在全球疾病负担(GBD)研究作者中,将残疾调整生命年(DALY)主要作为描述性健康指标已变得司空见惯。在GBD的第一阶段(1990-1996年),人们普遍承认DALY具有内在的评价假设。然而,自2010年GBD发布以来,DALY模型忽略了两个核心评估实践——时间贴现和年龄加权。经过这一重大修订后,现在出现的观点似乎是,DALY主要是一种描述性措施。我们在本文中的目的是证明,尽管DALY发生了变化,但它在很大程度上仍然是可评估的。我们的分析重点是通过比较DALY作为GBD出版物的两个最重要阶段(从开始(1990-1996年)到最近发布(2010-2017年)的疾病负担衡量标准,来了解DALY。我们确定了DALY背后的许多假设,并将它们归类为描述性或评估性。我们的结论是,虽然DALY模型可以说已经变得更具描述性,但它仍然是必要的,主要是评估性的。
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引用次数: 11
Public Health Ethics in a Pandemic. 大流行病中的公共卫生伦理。
IF 2.1 3区 哲学 Q1 Nursing Pub Date : 2020-10-28 eCollection Date: 2020-07-01 DOI: 10.1093/phe/phaa032
Marcel Verweij, Angus Dawson
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引用次数: 0
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Public Health Ethics
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