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Effective Management of Tongue Hemangioma Using Boiling 3% Hypertonic Saline Injections: A Case Report from a Resource-Limited Setting. 煮沸3%高渗盐水注射有效治疗舌血管瘤:一例资源有限的病例报告。
IF 0.4 Q4 SURGERY Pub Date : 2025-08-01 Epub Date: 2025-05-31 DOI: 10.1007/s12070-025-05585-3
Gautam Kumar Arora, Urvashi Mishra, Poonam Lohchab, Harpreet Singh

Tongue hemangiomas, though benign, can lead to significant complications and discomfort in affected individuals. This case report details the management of a symptomatic tongue hemangioma using multiple injections of 3% boiling saline in a 13-year-old boy treated at a peripheral government hospital in India, emphasising the approach's efficacy and practicality within a financially constrained environment.

舌血管瘤虽然是良性的,但会导致严重的并发症和不适。本病例报告详细介绍了在印度一家外围政府医院治疗的一名13岁男孩多次注射3%煮沸生理盐水治疗有症状的舌血管瘤的情况,强调了该方法在经济拮据环境下的有效性和实用性。
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引用次数: 0
Clinical Outcomes and Patterns of Failure After Intensity-Modulated Radiotherapy with Simultaneous Integrated Boost for Nasopharyngeal Carcinoma: A Single Institutional Review. 调强放疗同时综合增强治疗鼻咽癌后的临床结果和失败模式:一项单一的机构回顾。
IF 0.4 Q4 SURGERY Pub Date : 2025-08-01 Epub Date: 2025-05-24 DOI: 10.1007/s12070-025-05539-9
Isha B Shah, Vinay Shivhare, Satyajeet Rath, Niranjan K Dash, Ankita Parikh, U Suryanarayan Kunikullaya, T Arun, Akash Pandya

With conformal radiotherapy techniques, acute and late toxicities can be reduced because of significantly better dose conformity and reduced doses to normal tissue. With Intensity Modulated Radiation Therapy (IMRT) further dose escalation is possible. To evaluate clinical outcomes and patterns of failure after IMRT-SIB (Simultaneous integrated boost)/(Volumetric modulated arc therapy) VMAT technique in nasopharyngeal cancer patients. It is a retrospective analysis of 60 nasopharyngeal squamous cell carcinoma patients, treated with IMRT/VMAT radiotherapy and chemotherapy to primary and bilateral cervical nodes from March 2017 to December 2021. 60 patients received definitive treatment using IMRT-SIB. Patients were monitored during and after treatment for local and regional failure, distant metastasis, locoregional progression free and overall survival. Patient characteristics: median age 45; 75% male; 6.7% Stage I, 18.3% Stage II, 43.3% Stage III, 31.7% Stage IVA. The median follow up was 24.5 months (range 5.5-75.6). The 2-year local control, regional control, distant metastasis free, locoregional progression free and overall survival rates are 81.5, 82.9, 86.9, 77.7, 92.9%, respectively. 11 patients failed at the local site and 10 patients failed at regional sites, median time to failure was 12.2 months. The 5-year estimated regional control rate for N0 vs N + disease was 100% vs 74.2%(p-0.07). IMRT-SIB is a safe and acceptable treatment option for patients with carcinoma nasopharynx. The pattern of local failure within the target volume suggests locally advanced T stage disease may require a higher biologic dose to gross tumor.

Supplementary information: The online version contains supplementary material available at 10.1007/s12070-025-05539-9.

采用适形放射治疗技术,由于剂量一致性显著提高和对正常组织的剂量减少,可减少急性和晚期毒性。强度调节放射治疗(IMRT)可以进一步增加剂量。评估IMRT-SIB(同步集成增强)/(体积调节电弧治疗)VMAT技术在鼻咽癌患者中的临床结果和失败模式。回顾性分析2017年3月至2021年12月60例接受IMRT/VMAT放疗和化疗的原发性和双侧宫颈结鼻咽癌患者。60例患者接受了IMRT-SIB的最终治疗。在治疗期间和治疗后监测患者的局部和区域失败,远处转移,局部无进展和总生存期。患者特征:中位年龄45岁;男性75%;6.7% I期,18.3% II期,43.3% III期,31.7% IVA期中位随访时间为24.5个月(范围5.5-75.6)。2年局部控制、局部控制、无远处转移、无局部进展和总生存率分别为81.5、82.9、86.9、77.7、92.9%。局部失败11例,局部失败10例,中位失败时间为12.2个月。N0和N +疾病的5年估计区域控制率分别为100%和74.2%(p-0.07)。对于鼻咽癌患者来说,IMRT-SIB是一种安全且可接受的治疗选择。靶体积内局部失败的模式提示局部晚期T期疾病可能需要更高的生物剂量。补充资料:在线版本包含补充资料,下载地址:10.1007/s12070-025-05539-9。
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引用次数: 0
Microbial Profiles and Antibiotic Resistance in Chronic Otorrhea: An Evaluation of Operated and Non-operated Patients. 慢性耳漏的微生物特征和抗生素耐药性:手术和非手术患者的评估。
IF 0.4 Q4 SURGERY Pub Date : 2025-08-01 Epub Date: 2025-06-11 DOI: 10.1007/s12070-025-05625-y
Aynur Aliyeva, Elif Sari

This study aims to compare the microbial profiles and antibiotic resistance patterns in chronic otorrhea patients with and without surgical intervention, identifying key differences to guide personalized and evidence-based treatment strategies. A retrospective analysis of 120 patients diagnosed with chronic otitis media and otorrhea was conducted. Patients were divided into operated (n = 60) and non-operated (n = 60) groups. Microbial identification and antibiotic susceptibility testing were performed using standard microbiological methods. Statistical analyses assessed differences in microbial prevalence and resistance patterns between groups. Pseudomonas aeruginosa was the most common microorganism in both groups but was significantly more prevalent in the non-operated group (77.8% vs. 53.33%, p < 0.05). Escherichia coli was significantly higher in the operated group (17.78% vs. 3.7%, p < 0.05). Staphylococcus aureus showed no significant difference in prevalence but exhibited resistance exclusively in the operated group. Antibiotic resistance to Ciprofloxacin, Ceftazidime, and Ticarcillin-Clavulanate was high for Pseudomonas aeruginosa in both groups, with no significant differences. Escherichia coli displayed significantly higher resistance to Ampicillin-Sulbactam in the operated group (75.0% vs. 0%, p < 0.05). Operated and non-operated groups showed distinct microbial profiles and resistance patterns. Surgical interventions influence resistance development, particularly in Escherichia coli and Staphylococcus aureus. These findings underscore the importance of routine susceptibility testing to guide effective, individualized treatment and address multidrug-resistant pathogens.

本研究旨在比较手术干预前后慢性耳漏患者的微生物特征和抗生素耐药模式,确定关键差异,以指导个性化和循证治疗策略。对120例诊断为慢性中耳炎和耳漏的患者进行回顾性分析。患者分为手术组(n = 60)和非手术组(n = 60)。采用标准微生物学方法进行微生物鉴定和药敏试验。统计分析评估了组间微生物流行率和耐药模式的差异。铜绿假单胞菌是两组中最常见的微生物,但在非手术组中患病率明显高于非手术组(77.8%比53.33%);p型大肠杆菌在手术组中患病率明显高于非手术组(17.78%比3.7%);p型金黄色葡萄球菌在手术组中患病率无显著差异,但仅在手术组中出现耐药性。两组铜绿假单胞菌对环丙沙星、头孢他啶和替卡西林-克拉维酸盐的耐药性均较高,差异无统计学意义。手术组大肠埃希菌对氨苄西林-舒巴坦的耐药率为75.0%,金黄色葡萄球菌和大肠埃希菌的耐药率为0%。这些发现强调了常规药敏试验对指导有效、个体化治疗和解决多重耐药病原体的重要性。
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引用次数: 0
Exploring the Interplay Between Physical Activity and Idiopathic Tinnitus Management: A Scoping Review on Severity Modulation and Perceptual Outcomes. 探索身体活动与特发性耳鸣管理之间的相互作用:对严重程度调节和知觉结果的范围审查。
IF 0.4 Q4 SURGERY Pub Date : 2025-08-01 Epub Date: 2025-06-02 DOI: 10.1007/s12070-025-05594-2
Abhishek Sharma, Nidhi Sharma, Aksh Chahal, Richa Hirendra Rai, Bartosz Maciej Wójcik

Tinnitus, a condition characterized by the perception of ringing or buzzing in the ears, affects millions of individuals worldwide, often leading to significant distress, impaired quality of life, and mental health concerns. Despite the widespread nature of tinnitus, effective treatment strategies remain limited, with few established guidelines for management. Recent studies suggest that Physical Activity may play a role in modulating tinnitus severity and perception, providing potential relief for sufferers. This scoping review aims to systematically explore the current body of evidence regarding the impact of physical activity on idiopathic tinnitus, specifically focusing on its effects on severity, perception, and related symptoms. Through an extensive search of databases such as PubMed, Scopus, and Web of Science, studies were examined on investigating various forms of physical activity, including aerobic exercises, resistance training, yoga and mind-body interventions. Key outcomes assessed include changes in tinnitus loudness, annoyance, and quality of life. The review also highlights potential physiological mechanisms underlying the observed effects, including the modulation of neuroplasticity, stress reduction and the improvement of cardiovascular and musculoskeletal health. Preliminary findings indicate that regular physical activity may offer a beneficial adjunctive approach to idiopathic tinnitus management, particularly for individuals with comorbid conditions such as anxiety, depression, and sleep disturbances. However, the current evidence is limited and heterogeneous, underscoring the need for further well-designed clinical trials to better define the optimal types, intensity, and duration of physical activity interventions.

Supplementary information: The online version contains supplementary material available at 10.1007/s12070-025-05594-2.

耳鸣是一种以耳鸣或嗡嗡声为特征的疾病,影响着全世界数百万人,通常会导致严重的痛苦、生活质量受损和精神健康问题。尽管耳鸣的广泛性质,有效的治疗策略仍然有限,很少有既定的指导方针的管理。最近的研究表明,体育活动可能在调节耳鸣的严重程度和感觉方面发挥作用,为患者提供潜在的缓解。本综述旨在系统地探讨体育活动对特发性耳鸣影响的现有证据,特别关注其对严重程度、感知和相关症状的影响。通过对PubMed、Scopus和Web of Science等数据库的广泛搜索,研究人员对各种形式的体育活动进行了调查,包括有氧运动、阻力训练、瑜伽和身心干预。评估的主要结果包括耳鸣响度、烦恼和生活质量的变化。该综述还强调了观察到的影响的潜在生理机制,包括调节神经可塑性,减轻压力和改善心血管和肌肉骨骼健康。初步研究结果表明,规律的身体活动可能为特发性耳鸣治疗提供有益的辅助方法,特别是对于患有焦虑、抑郁和睡眠障碍等合并症的个体。然而,目前的证据是有限的和异质性的,强调需要进一步精心设计的临床试验,以更好地确定体育活动干预的最佳类型、强度和持续时间。补充信息:在线版本包含补充资料,提供地址为10.1007/s12070-025-05594-2。
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引用次数: 0
Head Neck Tuberculosis Amidst COVID Pandemic: An Assessment of Change in Disease Dynamics. COVID大流行期间头颈部结核病:疾病动态变化评估
IF 0.4 Q4 SURGERY Pub Date : 2025-08-01 Epub Date: 2025-05-31 DOI: 10.1007/s12070-025-05592-4
Saikat Samaddar, Mainak Maitra, Debasish Ghosh, Sangita Bhattacharya Samaddar, Saibal Mondal, Debasis Barman, Arunabha Sengupta

COVID 19 pandemic has had its effect on the entire world population. The purpose of the study was to perform Epidemiological and Head Neck site wise assessment of Tuberculosis (TB) presentation and investigation during and immediately after the COVID 19 pandemic. The changing incidence and atypical presentations were documented. Institution based retrospective study was conducted and the data of Head Neck TB (HN- TB) was extracted from the patient registers of National Tuberculosis Elimination Programme (NTEP) of the same institute during the period of March 1st 2020 to 31st December 2022. Statistical analysis was done to satisfy the investigative purpose. In the study period 2118 patients were registered for TB. 279 patients were diagnosed with HN-TB as the primary site of involvement. Cervical Lymph node TB was the predominantly involved site followed by Head Neck Skin, Ear, Larynx, Ophthalmological structures, Facial bones, Oral cavity and Oropharynx, Neck sinus. The Incidence of TB as a whole and HN- TB saw uneven rise and fall with respect to its incidence during and after the pandemic. There were definite variations in the incidence of site specific involvement of HN- TB when compared to world literature. Changing disease dynamics comes as a challenge before NTEP amidst the prevailing pandemic. No particular investigation is full proof to detect tuberculosis and so, attempts should be made to maximise the number of detection options. Lessons should be learnt from the present situation to keep us prepared for the future.

2019冠状病毒病大流行对全世界人口产生了影响。该研究的目的是在COVID - 19大流行期间和之后立即对结核病(TB)的表现和调查进行流行病学和头颈部位明智评估。记录了发病率的变化和非典型表现。采用基于机构的回顾性研究,提取该研究所2020年3月1日至2022年12月31日国家消除结核病规划(NTEP)患者登记簿中的头颈结核(HN- TB)数据。为了满足调查目的,进行了统计分析。在研究期间,有2118名结核病患者登记。279例患者被诊断为HN-TB,作为主要受累部位。颈部淋巴结结核是主要受累部位,其次是头颈部皮肤、耳部、喉部、眼部结构、面部骨骼、口腔和口咽、颈部窦。在大流行期间和之后,整体结核病和HN- TB的发病率出现了不均匀的上升和下降。与世界文献相比,在部位特异性受累的HN- TB发病率方面有明确的变化。在当前的大流行中,不断变化的疾病动态是NTEP面临的挑战。没有一项特别的调查能充分证明可以发现结核病,因此,应努力使发现方法的数量最大化。我们应该从目前的情况中吸取教训,为将来做好准备。
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引用次数: 0
Impact of Early Surgical Intervention on Recovery of Gustatory Function in Patients with Chronic Otitis Media. 早期手术干预对慢性中耳炎患者味觉功能恢复的影响。
IF 0.4 Q4 SURGERY Pub Date : 2025-08-01 Epub Date: 2025-05-29 DOI: 10.1007/s12070-025-05524-2
K Periyal, P M Raghuraman, G Selvarajan, Pradeep Dhanapal

Chronic otitis media is inflammation of mucoperiosteal lining of medial ear cleft which leads to bacterial colonization which inturn releases enzymes and toxins. Chorda tympani have an unprotected course in the middle ear running across the tympanic cavity from its posterior to anterior wall, supplying anterior two third of tongue making it easily amendable to the enzymes, cytokines and bacterial toxins released in the middle ear reflecting in its function. In this survey we have studied the impact of early surgical intervention on chorda tympani nerve's function in patients with chronic otitis media. In this study we included 90patients with COM fit for surgical intervention who were divided into 3groups based on the duration of the disease as < 5 years, 5-10 years and > 10 years. Each group were evaluated for 5different taste sensations over the anterior 2/3rd of tongue bilaterally by assigning a score of 0-15 preoperatively, 2 weeks postoperative and 8 weeks postoperatively and scores compared. It was noted that left side preponderance for the disease was more than right with a male predominance of 54.4%. Patients with history for < 5 years showed better improvement curve during postoperative follow-up when compared with the other two groups and least improvement noticed in the group with COM history for > 10 years.Similarly participants with more duration of dry ear showed better results. Early surgical intervention can prevent further deterioration of the nerve function and helps in achieving its complete recovery.

慢性中耳炎是内耳裂粘膜层的炎症,导致细菌定植,进而释放酶和毒素。中耳脊索在中耳中有一条无保护的路线,从后壁到前壁穿过鼓室,供应舌头前三分之二,使其容易适应中耳释放的酶、细胞因子和细菌毒素,反映其功能。在这项调查中,我们研究了早期手术干预对慢性中耳炎患者鼓室索神经功能的影响。本研究纳入90例适合手术治疗的COM患者,按病程10年分为3组。术前、术后2周、术后8周分别对两组患者舌前2/3的5种不同味觉感觉进行评分,并进行比较。我们注意到该病的左侧优势大于右侧优势,男性优势为54.4%。病史为10年的患者。同样,干耳持续时间越长的参与者表现出更好的结果。早期手术干预可防止神经功能进一步恶化,有助于实现神经功能的完全恢复。
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引用次数: 0
Therapeutic Strategies in Recurrent Oral and Sinusal Fistulas: Case Report and Literature Review. 复发性口窦瘘的治疗策略:病例报告及文献复习。
IF 0.4 Q4 SURGERY Pub Date : 2025-08-01 Epub Date: 2025-06-04 DOI: 10.1007/s12070-025-05657-4
Carlos Leone Faria Moreira, Frederico Coimbra da Rocha, Yuri de Lima Medeiros, Eduardo Stehling Urbano

The therapeutic approach for buccosinusal fistula (BSF) requires careful consideration of factors such as infection status, bone defect size, and epithelialization. The literature describes three primary treatment options: vestibular flap, buccal fat pad, and palatal flap. This study aims to report a clinical case of recurrent BSF after five surgical interventions and review current literature on treatment modalities. A 42-year-old female patient underwent extraction of the upper left first molar, followed by alveolar bone grafting, evolving into buccosinusal communication (BSC). Over 45 days, she underwent five surgical interventions using the vestibular flap technique, which failed to prevent epithelialization and led to aesthetic and functional complications, such as facial asymmetry and displacement of the parotid papilla. As an alternative, a rotated split palatal flap was employed. After six months of follow-up, complete closure of the BSC was observed, with no signs of sinus pathology or raw areas at the donor site, indicating satisfactory healing and successful treatment. Literature shows that while vestibular flaps are commonly used, they often fail in large or recurrent defects due to tension and limited vascularization. Buccal fat pads offer good coverage but may not suffice for extensive areas. Palatal flaps stand out for their robust blood supply from the greater palatine artery, thicker tissue, and high success rates, particularly in previously treated cases. Thus, they are strongly indicated for refractory BSF cases. The palatal flap is an effective, reliable alternative for BSF management, especially in complex cases.

颊窦瘘(BSF)的治疗方法需要仔细考虑感染状态、骨缺损大小和上皮化等因素。文献描述了三种主要的治疗选择:前庭瓣,颊脂肪垫和腭瓣。本研究旨在报告一例经过五次手术治疗后复发性脑脊髓炎的临床病例,并回顾目前有关治疗方法的文献。一位42岁的女性患者接受了左上第一磨牙的拔除,随后进行了牙槽骨移植,发展为牙槽骨连接(BSC)。在45天内,她接受了5次前庭皮瓣手术干预,未能阻止上皮化,导致美学和功能并发症,如面部不对称和腮腺乳头移位。作为替代,旋转裂腭瓣被采用。随访6个月后,观察到BSC完全闭合,供体部位没有鼻窦病理或生区迹象,表明愈合满意,治疗成功。文献显示,虽然前庭皮瓣被广泛使用,但由于紧张和有限的血管化,它们经常在大的或复发的缺陷中失败。颊脂肪垫提供了良好的覆盖,但可能不足以覆盖大面积区域。腭瓣以其来自腭大动脉的强劲血液供应,较厚的组织和高成功率而突出,特别是在先前治疗过的病例中。因此,它们强烈适用于难治性脑脊膜炎病例。腭瓣是一种有效、可靠的治疗BSF的方法,特别是在复杂的病例中。
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引用次数: 0
Tinnitus Severity and Auditory Brainstem Response: A Correlative Study. 耳鸣严重程度与听觉脑干反应的相关性研究。
IF 0.4 Q4 SURGERY Pub Date : 2025-08-01 Epub Date: 2025-05-29 DOI: 10.1007/s12070-025-05616-z
Sanjay Kumar, Anghusman Dutta, Rashmi Natraj, Sachin Bhatt, Inderpal Singh Walia, Helvin C Francis

Introduction: Tinnitus, defined as the perception of sound without an external stimulus, affects approximately 10-15% of the world population, often resulting in significant emotional and functional impairments. Despite advancements in diagnostic approaches, the relationship between subjective tinnitus severity and objective auditory brainstem response (ABR) findings remains poorly understood. This study evaluates these associations to enhance understanding of tinnitus pathophysiology and formulate clinical practice.

Methodology: This prospective, observational study included 50 adults (aged 18-65 years) with chronic tinnitus lasting six months or longer and normal, mild, or moderate hearing loss (hearing thresholds ≤ 55 dB HL), as determined by pure-tone audiometry. Tinnitus severity was assessed using the Tinnitus Functional Index (TFI), evaluating domains such as intrusiveness, emotional distress, and quality of life. Auditory brainstem response (ABR) testing analysed wave latencies (I, III, V) and inter-peak intervals (I-III, III-V, I-V). Correlations between TFI scores, ABR parameters, and demographic factors, including age and tinnitus duration, were examined.

Results: TFI scores demonstrated severe impacts on quality of life, intrusiveness, and emotional distress. ABR testing revealed abnormalities in 25% of participants, particularly prolonged Wave V latency and I-V interval. Significant correlations were observed between Intrusiveness and Wave V latency (r = 0.35, p = 0.018) and between Emotional Distress and the I-V interval (r = 0.40, p = 0.010). Older participants and those with longer tinnitus duration exhibited higher severity and more pronounced ABR abnormalities.

Conclusion: This study establishes a significant association between subjective tinnitus severity and objective auditory brainstem dysfunction, emphasizing the neural basis of tinnitus. The findings highlight the importance of integrating subjective and objective assessments in clinical evaluation to guide personalized therapeutic strategies.

Supplementary information: The online version contains supplementary material available at 10.1007/s12070-025-05616-z.

耳鸣,定义为没有外界刺激的声音感知,影响了大约10-15%的世界人口,通常导致严重的情绪和功能障碍。尽管诊断方法取得了进步,但主观耳鸣严重程度与客观听觉脑干反应(ABR)结果之间的关系仍然知之甚少。本研究评估这些关联,以增进对耳鸣病理生理的了解,并制定临床实践。方法:这项前瞻性观察性研究纳入了50名慢性耳鸣持续6个月或更长时间、正常、轻度或中度听力损失(听力阈值≤55 dB HL)的成年人(年龄18-65岁),由纯音听力测定测定。使用耳鸣功能指数(TFI)评估耳鸣严重程度,评估侵入性、情绪困扰和生活质量等领域。听觉脑干反应(ABR)测试分析波潜伏期(I, III, V)和峰间间隔(I-III, III-V, I-V)。检查TFI评分、ABR参数和人口统计学因素(包括年龄和耳鸣持续时间)之间的相关性。结果:TFI评分显示对生活质量、侵入性和情绪困扰有严重影响。ABR测试显示25%的参与者异常,特别是延长波V潜伏期和I-V间隔。侵入性与V波潜伏期呈显著相关(r = 0.35, p = 0.018),情绪困扰与I-V波间隔呈显著相关(r = 0.40, p = 0.010)。年龄较大的参与者和耳鸣持续时间较长的参与者表现出更高的严重程度和更明显的ABR异常。结论:本研究确立了主观性耳鸣严重程度与客观听性脑干功能障碍之间的显著相关性,强调了耳鸣的神经基础。研究结果强调了在临床评估中整合主观和客观评估以指导个性化治疗策略的重要性。补充信息:在线版本包含补充资料,地址为10.1007/s12070-025-05616-z。
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引用次数: 0
Trigemino-Abducens Synkinesis Involving the Malleolar Muscle. an Exceptional Case. 涉及踝肌的三叉肌-外展肌联动。例外情况。
IF 0.4 Q4 SURGERY Pub Date : 2025-08-01 Epub Date: 2025-06-10 DOI: 10.1007/s12070-025-05584-4
Andrés González Fernández, Manuela Del Carmen Zapata, Ignacio Sanhueza Torres, Sheila Huerga Miguélez

Trigemino-abducens synkinesis is a rare neurological condition scarcely discussed in the current bibliography. The few cases are related to synkinesis involving the masticatory muscles, but there are no reports associated to the malleolar muscle. We report a 56 years old woman with annoying feeling inside the right ear when she looks to the same side. Examining this ear, we can identify some eardrum movements when the patient looks to the right. We diagnose this synkinesis and we offer a surgical solution after the poor efficacy of the neurological treatment.

Supplementary information: The online version contains supplementary material available at 10.1007/s12070-025-05584-4.

三叉肌-外展肌联动是一种罕见的神经系统疾病,在目前的文献中很少讨论。少数病例与咀嚼肌的联合运动有关,但没有与踝肌相关的报道。我们报告了一位56岁的女性,当她看向同一侧时,右耳内有烦人的感觉。检查这只耳朵,当病人向右看时,我们可以发现一些鼓膜的运动。我们诊断这种联动性,并在神经治疗效果不佳后提供手术解决方案。补充资料:在线版本包含补充资料,下载地址:10.1007/s12070-025-05584-4。
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引用次数: 0
When Appearances Deceive: From Poorly Differentiated Carcinoma to unveiling Olfactory Neuroblastoma in a Highly Vascular Sinonasal tumor. 当外表欺骗:从低分化癌到高血管性鼻窦肿瘤的嗅神经母细胞瘤。
IF 0.4 Q4 SURGERY Pub Date : 2025-08-01 Epub Date: 2025-05-31 DOI: 10.1007/s12070-025-05582-6
Anupam V Mohan, Vijay Bidkar, Dharanya G S, Saikat Mitra, Sandeep Dabhekar, Kiran Kumar Prathipati

Sinonasal tumors are an uncommon pathological entity, often presenting with overlapping clinical and radiological features, which makes their diagnosis particularly challenging. Less than 2% of these are vascular tumors, with their diagnoses ranging from benign to malignant conditions. Even with advanced imaging techniques such as computed tomography (CT) and magnetic resonance imaging (MRI), which provide a near-accurate picture of the extent of the disease, distinguishing them between benign and malignant vascular tumors remains difficult. We present the case of a 42-year-old female who experienced a year-long history of nasal obstruction, severe headache, and intermittent unilateral nasal bleeding. Imaging revealed a highly vascular sinonasal tumor, raising the possibility of benign vascular neoplasms, though malignant tumors were also considered a rare differential. Subsequent surgical excision and frozen section analysis revealed a poorly differentiated sinonasal squamous cell carcinoma. However, postoperative histopathology confirmed the diagnosis of Olfactory Neuroblastoma. The patient underwent combined surgical resection followed by postoperative chemotherapy. This case report highlights the challenges associated with the diagnosis of sinonasal tumors and the significance of histopathological evaluation as the key to unveil the final diagnosis.

鼻窦肿瘤是一种罕见的病理实体,通常表现为重叠的临床和影像学特征,这使得其诊断特别具有挑战性。其中不到2%是血管肿瘤,其诊断从良性到恶性不等。即使有先进的成像技术,如计算机断层扫描(CT)和磁共振成像(MRI),这些技术可以提供近乎准确的疾病范围图像,但区分良性和恶性血管肿瘤仍然很困难。我们提出的情况下,42岁的女性谁经历了一年的鼻塞,严重的头痛和间歇性单侧鼻出血的历史。影像学显示高度血管性鼻窦肿瘤,增加良性血管肿瘤的可能性,尽管恶性肿瘤也被认为是罕见的鉴别诊断。随后的手术切除和冰冻切片分析显示为低分化鼻窦鳞状细胞癌。然而,术后组织病理学证实了嗅觉神经母细胞瘤的诊断。患者接受联合手术切除和术后化疗。本病例报告强调了与鼻窦肿瘤诊断相关的挑战,以及组织病理学评估作为揭示最终诊断的关键的意义。
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Indian Journal of Otolaryngology and Head and Neck Surgery
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