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Closing the Gap: Exploring the Role of Cap Grafts in Tracheocutaneous Fistula Closure. 缩小差距:探索帽状移植在气管皮肤瘘闭合中的作用。
IF 0.6 Q4 SURGERY Pub Date : 2024-08-01 Epub Date: 2024-03-19 DOI: 10.1007/s12070-024-04588-w
T B Shashidhar, Karthik Balakrishnan, Indresh Chandra

Exploring the Role of Cap Grafts in tracheocutaneous fistula Closure. A tracheocutaneous fistula (TCF) is an abnormal connection that forms between the trachea (windpipe) and the skin of the neck. If spontaneous closure does not occur, fibrosis of the surrounding tissue may result in a persistent TCF and in some cases, iatrogenic laryngotracheal stenosis at the level of tracheostoma, the so-called A-frame deformity. In all 5 patients, Conchal cartilage was harvested. The new de-epithelialized stoma is measured, and the previously harvested graft is cut to match the defect. Passing through the centre of the tracheal cartilage and into the centre of the auricular cartilage graft, 3-0 PDS, horizontal mattress sutures are placed sequentially around the periphery of the graft, stabilised with Right SCM flap and skin was closed in layers. In each of the five cases, we achieved a resounding success by skilfully closing the fistulas and meticulously restoring the structural integrity. Equally noteworthy, all patients expressed contentment with the cosmetic outcomes at both the donor site and the neck region, deeming it as an acceptable aesthetic result.

探索帽状移植在气管皮肤瘘闭合中的作用。气管皮肤瘘(TCF)是气管(气管)和颈部皮肤之间形成的异常连接。如果不能自发闭合,周围组织的纤维化可能会导致气管瘘持续存在,在某些情况下还会造成气管瘤水平的先天性喉气管狭窄,即所谓的 A 框畸形。在所有 5 名患者中,均采集了海螺软骨。测量新的去上皮化气管造口,然后切割之前采集的移植物,使其与缺损处相匹配。穿过气管软骨中心,进入耳廓软骨移植物中心,在移植物周边依次放置 3-0 PDS 水平褥式缝合线,用右侧胸肌瓣稳定,并分层缝合皮肤。在这五例手术中,我们都取得了巨大成功,巧妙地关闭了瘘管,并细致地恢复了结构的完整性。同样值得注意的是,所有患者都对供体部位和颈部的美容效果表示满意,认为这是可以接受的美学效果。
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引用次数: 0
Malignant Nerve Sheath Tumour - A Case Report. 恶性神经鞘瘤--病例报告。
IF 0.6 Q4 SURGERY Pub Date : 2024-08-01 Epub Date: 2024-04-26 DOI: 10.1007/s12070-024-04591-1
C S Majitha, Suresh Pillai, Shama Shetty, Kailesh Pujary, Girish Menon

Malignant nerve sheath tumors are rare and aggressive soft tissue sarcomas. They contribute to 5-10% of all soft tissue sarcomas. They can be sporadic, occur in patients with NF1 (neurofibromatosis 1) or can occur after radiation therapy. A high rate of recurrence and hematogenous metastasis is seen in these patients. They are also associated with poor prognosis. A case of malignant nerve sheath tumor seen in a 44-year-old male with pre-existing NF1 is being discussed here due to the unique nature of the disease and its rarity.

恶性神经鞘瘤是一种罕见的侵袭性软组织肉瘤。它们占所有软组织肉瘤的 5-10%。恶性神经鞘瘤可能是散发性的,也可能发生在 NF1(神经纤维瘤病 1)患者身上,或在放射治疗后发生。这些患者的复发率和血行转移率很高。它们的预后也很差。由于该病的特殊性和罕见性,本文将讨论一例 44 岁男性恶性神经鞘瘤患者的病例。
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引用次数: 0
Primary Typical Meningioma of the Sphenoid Sinus: A Case Report and Literature Review. 蝶窦原发性典型脑膜瘤:病例报告与文献综述
IF 0.6 Q4 SURGERY Pub Date : 2024-08-01 Epub Date: 2024-04-26 DOI: 10.1007/s12070-024-04722-8
Jian Xiong, Nini Li, Yuxi Wu

Primary cranial meningioma is extremely rare and only rarely described in clinical practice, as is primary sinus ectopic meningioma. We detailed the surgical management of a female patient, aged 83, who had a primary meningioma of the sphenoid sinus. This uncommon clinical entity was the subject of a study of the literature, and its prognosis was summarized.

Supplementary information: The online version contains supplementary material available at 10.1007/s12070-024-04722-8.

原发性头颅脑膜瘤和原发性鼻窦异位脑膜瘤一样极为罕见,在临床实践中也鲜有描述。我们详细介绍了一名 83 岁女性患者的手术治疗情况,她患有蝶窦原发性脑膜瘤。我们对这一不常见的临床病例进行了文献研究,并对其预后进行了总结:在线版本包含补充材料,可在 10.1007/s12070-024-04722-8上查阅。
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引用次数: 0
Atypical Intramuscular Lipoma of the Tongue. Case Report. 舌头上的非典型肌内脂肪瘤。病例报告。
IF 0.6 Q4 SURGERY Pub Date : 2024-08-01 Epub Date: 2024-04-26 DOI: 10.1007/s12070-024-04711-x
Savvas Achilleos, Tsintzos Symeon, Anastasopoulou Evi

Although they are frequently benign tumors of mesenchymal origin, lipomas sporadically develop in the oral cavity. Intramuscular lipomas, which originate inside muscles, are a rare subtype. When found in the tongue, they are considerably more uncommon and its etiology remains unclear. Histological examination of the specimen shows mature adipocytes of uniform size with minimal vascularization and sometimes striated muscle fibers are to be seen in the periphery. A yellowish submucosal mass that is slowly expanding, painless, and asymptomatic, is typically seen based on a patient's history and clinical examination. Lipomas that occur in uncommon locations should be mentioned and should be considered in the differential diagnosis of an oral mass. The main treatment option is a complete surgical excision. The purpose of this report is to describe a case of a 43-year-old female patient with an atypical, well-defined intramuscular lipoma in her tongue that began to form around 10 months ago.

脂肪瘤通常是间质来源的良性肿瘤,但也有零星发生在口腔的脂肪瘤。肌肉内脂肪瘤起源于肌肉内部,是一种罕见的亚型。在舌头上发现的脂肪瘤则更为罕见,其病因仍不清楚。标本的组织学检查显示,成熟的脂肪细胞大小一致,血管极少,有时在外围可见横纹肌纤维。根据患者的病史和临床检查,通常会发现一个缓慢扩张、无痛、无症状的淡黄色粘膜下肿块。应提及发生在不常见部位的脂肪瘤,并在口腔肿块的鉴别诊断中予以考虑。主要的治疗方法是完全手术切除。本报告的目的是描述一例 43 岁女性患者的病例,她的舌头上长有一个不典型的、轮廓清晰的肌内脂肪瘤,大约 10 个月前开始形成。
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引用次数: 0
Immunotherapy: The Fourth Domain in Oral Cancer Therapeutics. 免疫疗法:口腔癌治疗的第四个领域
IF 0.6 Q3 Medicine Pub Date : 2024-06-01 Epub Date: 2024-03-10 DOI: 10.1007/s12070-024-04565-3
Ruby Dwivedi, Ayushi Jain, Shalini Gupta, Shaleen Chandra

Owing to high global prevalence, incidence and associated mortality, cancer of head and neck particularly oral cancer remains a cardinal domain for research and trials. Immune-modulatory therapies that employ patients own immune system for therapeutic benefits in oral cancer seems promising. The aim of this review is to gauge the potential of immunotherapy as fourth domain of Oral cancer therapeutics. Articles were searched using suitable search terms in MEDLINE and Google Scholar database to include clinical trials, meta-analyses, and research in humans/animals/cell lines published in peer reviewed journals. A total of 97 articles were included in this review. Literature has several studies and trials where different types of immunotherapies has been attempted but it is crucial to identify precise biomarkers of genome based targeted agents and to find parameters to select patients who might benefit from immunotherapy. Also further research is required to estimate predictive value of tumor mutational burden and mutational signatures so as to aid in personalized prediction of oral cancer therapeutic response.

由于头颈部癌症,尤其是口腔癌在全球的流行率、发病率和相关死亡率都很高,因此口腔癌仍然是研究和试验的主要领域。免疫调节疗法利用患者自身的免疫系统来治疗口腔癌,似乎很有前景。本综述旨在评估免疫疗法作为口腔癌治疗的第四个领域的潜力。我们在 MEDLINE 和 Google Scholar 数据库中使用合适的检索词对文章进行了检索,包括在同行评审期刊上发表的临床试验、荟萃分析以及对人类/动物/细胞系的研究。本综述共收录了 97 篇文章。文献中有多项尝试不同类型免疫疗法的研究和试验,但关键是要确定基于基因组的靶向药物的精确生物标志物,并找到选择可能从免疫疗法中获益的患者的参数。此外,还需要进一步研究肿瘤突变负荷和突变特征的预测价值,以帮助对口腔癌治疗反应进行个性化预测。
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引用次数: 0
Impact of Surgeon's Experience and Tumor's Nature in the Use of Intraoperative Facial Nerve Monitoring in Superficial Parotidectomy. Preliminary Results from a Single-Center Retrospective Analysis. 外科医生经验和肿瘤性质对浅表腮腺切除术中使用术中面神经监测的影响。单中心回顾性分析的初步结果。
IF 0.6 Q3 Medicine Pub Date : 2024-06-01 Epub Date: 2024-03-04 DOI: 10.1007/s12070-024-04552-8
Luca de Campora, Francesca Atturo, Pietro De Luca, Marc Muller, Marco Radici, Angelo Camaioni, Enrico de Campora

To assess the effectiveness of intraoperative facial nerve monitoring (IFNM) compared to non-monitoring in the prevention of post-operative facial nerve palsy during superficial parotidectomy. Patients treated with curative intent for parotid gland tumors between January 2020 and January 2022 were included. The study population has been divided in 2 groups, based on IFNM: the group A included patients operated with IFNM, whilst group B was the non-monitoring group. A further classification focused on the pathologies and the surgeons' experience. The study group included 58 patients, 27 female and 31 male. The mean age was 45.7 yr (range 36-78). No statistical difference has been found in post-operative HB grade between group A and B. The analysis of patients affected by pleomorphic surface lobe adenomas of the parotid did not show a statistical difference in HB outcome (p > 0.05). The analysis of the effect of surgeons' experience in IFNM advantage did not show statistical difference for superficial parotid tumors. The results of the present study suggest that the use of IFNM during parotid surgery is not mandatory to preserve the VII nerve function, both in case of primary tumor and in case of recurrence, and even when surgery is performed by less experienced surgeon compared to those cases treated by a more experienced surgeon.

目的:评估术中面神经监测(IFNM)与非监测相比在预防浅表腮腺切除术术后面神经麻痹方面的效果。研究对象包括 2020 年 1 月至 2022 年 1 月期间接受治疗的腮腺肿瘤患者。研究对象根据IFNM分为两组:A组包括接受IFNM手术的患者,B组为未接受监测组。另一种分类方法侧重于病理和外科医生的经验。研究组包括 58 名患者,其中女性 27 人,男性 31 人。平均年龄为 45.7 岁(36-78 岁不等)。对腮腺多形性表面叶腺瘤患者的分析显示,HB结果没有统计学差异(P > 0.05)。外科医生的经验对 IFNM 优势的影响分析显示,浅表腮腺肿瘤患者的 IFNM 优势没有统计学差异。本研究结果表明,在腮腺手术中使用 IFNM 并不是保护 VII 神经功能的强制性措施,无论是在原发肿瘤还是复发的情况下,甚至在由经验较少的外科医生进行手术时,与由经验较多的外科医生进行治疗的病例相比也是如此。
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引用次数: 0
Assessment of Effects of Chronic Mobile Phone Usage on Auditory Functions: A Study at a Tertiary Care Teaching Hospital in Northern India. 评估长期使用手机对听觉功能的影响:印度北部一家三级教学医院的研究。
IF 0.6 Q3 Medicine Pub Date : 2024-04-01 Epub Date: 2023-12-02 DOI: 10.1007/s12070-023-04354-4
Pallavi Saroch, Gopika Kalsotra, Parmod Kalsotra

Genuine concerns are being increased regarding potential health risks associated with the radiation exposure while using mobile devices. To study the effects of mobile phone usage on auditory functions. The detailed history of the patient was obtained with special emphasis on total cumulative usage [in years], average daily use [in minutes]. According to the years of exposure, subjects were divided into Group A (< 5 years of exposure) and Group B (> 5 years of exposure) and according to the average daily usage of mobile phones, subjects were divided into Group 1 (< 60 min daily usage) and Group 2 (> 60 min of daily usage). After that systemic examination was done. Audiological testing included pure tone audiometry (PTA) with extended high frequencies (0.250-12 kHz), Otoacoustic emissions (OAE) and Auditory Brainstem response (ABR) testing and middle latency response (MLR) were performed. Out of 100 subjects, maximum subjects (38%) in the present study were in the age group of 21-30 years with male: female ratio of 1.6:1. The main associated complaints in the subjects at the time of enrolment in the study included ear warmth (34%) followed by aural fullness (20%) and tinnitus (17%). In Group A, mild SNHL was seen in 3 (11.54%) subjects in whom 2 had > 60 min average daily use and 1 had < 60 min daily use. In Group B 19 (25.68%) subjects had mild SNHL out of which 6 were in Group 2 and 13 were in Group 1. In group B 2 (2.7%) subjects had moderate SNHL. Increase in latencies of Na and Pa were noted with prolonged and frequent exposure to mobile phones in MLR. It is advised to limit the usage of mobile phones so as to reduce the damage caused by EMRs to the auditory system.

人们越来越关注使用移动设备时暴露在辐射中的潜在健康风险。研究使用手机对听觉功能的影响。研究人员详细询问了患者的病史,特别强调了累计使用时间(以年为单位)和平均每日使用时间(以分钟为单位)。根据接触手机的年数,受试者被分为 A 组(接触时间为 5 年);根据平均每天使用手机的时间,受试者被分为 1 组(每天使用时间为 60 分钟)。然后进行系统检查。听力测试包括扩展高频(0.250-12 kHz)纯音测听(PTA)、耳声发射(OAE)和听性脑干反应(ABR)测试以及中潜伏反应(MLR)。在 100 名受试者中,21-30 岁年龄段的受试者最多(38%),男女比例为 1.6:1。受试者加入研究时的主要相关主诉包括耳热(34%),其次是耳部饱胀感(20%)和耳鸣(17%)。在 A 组中,有 3 名受试者(11.54%)患有轻度 SNHL,其中 2 名受试者平均每天使用时间超过 60 分钟,1 名受试者平均每天使用时间超过 60 分钟。
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引用次数: 0
Swallowing the Unexpected: A Case Report on an Unusual Presentation of Esophageal Malignancy. 吞下意想不到的东西:关于食管恶性肿瘤异常表现的病例报告。
IF 0.6 Q3 Medicine Pub Date : 2024-04-01 Epub Date: 2023-12-27 DOI: 10.1007/s12070-023-04453-2
Iruvantika Malik, Sandeep S, Shilpa C

Head and neck malignancies presenting with a neck abscess as the primary symptom are uncommon and may result in a misdiagnosis or delay in diagnosis and appropriate treatment. Here we report on a rare case where a young adult presented with signs and symptoms of a retropharyngeal abscess, which was later identified as an esophageal malignancy.

以颈部脓肿为主要症状的头颈部恶性肿瘤并不常见,可能会导致误诊或延误诊断和适当的治疗。在此,我们报告了一个罕见病例,一名年轻成年人出现咽后脓肿的体征和症状,后被确定为食管恶性肿瘤。
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引用次数: 0
Case Series of Surgical Treatment in Pediatric Thyroid Carcinoma in a Single Institution. 单一机构小儿甲状腺癌手术治疗病例系列。
IF 0.6 Q3 Medicine Pub Date : 2024-04-01 Epub Date: 2023-12-04 DOI: 10.1007/s12070-023-04377-x
Diani Kartini, Merlynda Ayu Rara Dini

Introduction: The prevalence of thyroid carcinoma (TC) among pediatric and adolescent populations is infrequent, yet its global occurrence is escalating. Insufficient information pertaining to TC in the pediatric populace of Indonesia presents issues in the identification and management of patients with this condition. The objective of this study is to provide a detailed account of a collection of pediatric TC cases that were recorded at a tertiary care center throughout an extended interval of eight years.

Presentation of cases: The present study conducted a retrospective data analysis of ten patients who received a diagnosis of TC during the period spanning from 2014 to 2022. The present study focused on analyzing the clinical manifestation, diagnostic measures, treatment modalities, and immediate postoperative consequences of TC. All patients diagnosed with thyroid cancer exhibited the presence of neck lump. Nine patients underwent total thyroidectomy, while one patient underwent isthmolobectomy. The histopathologic evaluation confirmed the diagnosis of thyroid cancer in every individual. There were a significant number of patients, up to 50%, who encountered complications after undergoing surgery. Two patients reported the hoarseness of voice, whereas two other patients experienced the signs of hypocalcemia. Only one patient exhibited both these symptoms simultaneously.

Discussion: The implementation of total thyroidectomy as a surgical intervention in pediatric patients poses a notable challenge. Postoperative monitoring for potential complications following surgery for total thyroidectomy is imperative.

Conclusions: The current study provides evidence that the utilization of total thyroidectomy in combination with lymph node dissection as indicated in patients with lymph node metastases in pediatric patients with thyroid carcinoma leads to a significant reduction in the probability of recurrence of lymph node enlargement. During the performance of surgical procedures, meticulous observation plays a key role in mitigating the risk of postoperative complications, such as hypoparathyroidism, hypocalcemia, and injury to the recurrent laryngeal nerve. Thus, it is imperative to conduct follow-up procedures for post-surgical interventions among pediatric patients diagnosed with TC.

简介甲状腺癌(TC)在儿童和青少年群体中的发病率并不高,但其全球发病率却在不断上升。由于印尼儿童甲状腺癌相关信息不足,因此在识别和治疗甲状腺癌患者方面存在问题。本研究的目的是详细介绍一家三级医疗中心在长达八年的时间里记录的一系列儿科TC病例:本研究对 2014 年至 2022 年期间确诊为 TC 的 10 名患者进行了回顾性数据分析。本研究重点分析了TC的临床表现、诊断措施、治疗方式和术后即刻后果。所有确诊为甲状腺癌的患者均有颈部肿块。九名患者接受了甲状腺全切除术,一名患者接受了峡部切除术。组织病理学评估证实了每个人的甲状腺癌诊断。有多达 50% 的患者在接受手术后出现了并发症。两名患者出现声音嘶哑,另外两名患者出现低钙血症。只有一名患者同时出现了这两种症状:讨论:对小儿患者实施甲状腺全切除术是一项重大挑战。甲状腺全切除术后对潜在并发症的术后监测势在必行:目前的研究提供的证据表明,对有淋巴结转移的小儿甲状腺癌患者采用甲状腺全切除术联合淋巴结清扫术,可显著降低淋巴结肿大复发的概率。在手术过程中,细致入微的观察对于降低术后并发症(如甲状旁腺功能减退症、低钙血症和喉返神经损伤)的风险起着关键作用。因此,对确诊为TC的儿童患者进行术后干预的随访程序势在必行。
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引用次数: 0
Giant Pleomorphic Adenoma of Infratemporal Fossa: A Rare Case Report. 颞下窝巨型多形性腺瘤:罕见病例报告
IF 0.6 Q3 Medicine Pub Date : 2024-04-01 Epub Date: 2023-12-04 DOI: 10.1007/s12070-023-04394-w
Vishav Yadav, Sanjeev Bhagat, Dinesh Sharma, Ankita Aggarwal, Khushboo Goel

Of all the head and neck tumors, salivary gland tumors account to 3%. Pleomorphic adenomas are one of the most common benign tumors arising from major salivary glands, although it could also develop from minor salivary glands situated at accessory sites like nasal cavity, pharynx, parapharyngeal space, lacrimal glands etc. Tumors of infratemporal fossa are quite unusual, mainly because of its hidden location in retromaxillary region. We report an unusual case of 65 years old male presenting with complaint of progressive left cheek swelling for 4 years. FNAC revealed pleomorphic adenoma of minor salivary gland tumor. Intraoperatively a giant lobulated tumor was seen occupying almost whole space of infratemporal fossa, which was removed in-toto via open approach. Patient was kept on regular follow up with no evidence of recurrence reported till date.

在所有头颈部肿瘤中,唾液腺肿瘤占 3%。多形性腺瘤是最常见的良性肿瘤之一,多发于主要唾液腺,但也可发生于鼻腔、咽部、咽旁间隙、泪腺等附属部位的小唾液腺。颞下窝肿瘤非常罕见,主要是因为它位于颌后区的隐蔽位置。我们报告了一例不寻常的病例,65 岁的男性主诉左侧脸颊进行性肿胀 4 年。FNAC 显示为小唾液腺肿瘤的多形性腺瘤。术中发现一个巨大的分叶状肿瘤,几乎占据了颞下窝的整个空间,通过开放式手术将其切除。患者一直接受定期随访,至今没有复发的迹象。
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引用次数: 0
期刊
Indian Journal of Otolaryngology and Head and Neck Surgery
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