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Trick or Treat-Jack O'Lanterns Are NOT Good to Eat. 不给糖就捣蛋--杰克灯笼不能吃。
IF 1.4 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 Epub Date: 2024-06-09 DOI: 10.1177/10806032241258334
Kailee Pollock, Josh Trebach, Kevin Watkins
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引用次数: 0
Contributions of Griffith Pugh to Success on Mt. Everest and His Impact on the Advancement of Altitude and Environmental Physiology. 格里菲斯-普对成功登顶珠穆朗玛峰的贡献以及他对海拔和环境生理学发展的影响。
IF 1.4 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 Epub Date: 2024-06-11 DOI: 10.1177/10806032241259499
Mayowa A Olatunji, Stephen Cornish, Phillip Gardiner, Gordon G Giesbrecht

Griffith Pugh, MD (1909-1994), was a pioneer in altitude physiology. During World War II, he developed training protocols in Lebanon to improve soldier performance at altitude and in the cold. In 1951 he was chosen to join the British Everest team as a scientist. In preparation, he developed strategies for success on a training expedition on Cho Oyu in 1952. Results from Cho Oyu led to the use of supplemental oxygen at higher flow rates during ascent than used previously (4 L/min vs 2 L/min) and continued use (at a reduced rate of 2 L/min) during descent, enabling increased performance and improved mental acuity. Oxygen was also used during sleep, leading to improved sleep and warmth. Adequate hydration (∼3 L/day) was also stressed, and a more appealing diet led to improved nutrition and condition of the climbers. Improved hygiene practices and acclimatization protocols were also developed. These strategies contributed to the first successful summiting of Mount Everest in 1953. Pugh was then appointed as the lead scientist for a ground-breaking eight-and-a-half-month research expedition where the team was the first to overwinter at high altitude (5800 m) in the Himalayas. This current work summarizes Pugh's scientific contributions as they relate to success on Mount Everest and in inspiring future altitude research by generations of successful researchers.

格里菲斯-普(Griffith Pugh)医学博士(1909-1994 年)是高原生理学的先驱。二战期间,他在黎巴嫩制定了训练方案,以提高士兵在高海拔地区和寒冷环境中的表现。1951 年,他被选为英国珠峰登山队的科学家。在准备过程中,他制定了在1952年卓奥友峰训练探险中取得成功的策略。卓奥友峰探险的结果促使人们在上升过程中使用比以前流量更大的补充氧气(4 升/分钟对 2 升/分钟),并在下降过程中继续使用(流量减少为 2 升/分钟),从而提高了成绩,改善了精神敏锐度。睡眠时也使用了氧气,从而改善了睡眠和保暖。此外,还强调了充足的水分摄入(每天 3 升),以及更有吸引力的饮食,从而改善了登山者的营养和状况。此外,还制定了更好的卫生习惯和适应方案。这些策略为 1953 年首次成功登顶珠穆朗玛峰做出了贡献。随后,Pugh 被任命为一次为期八个半月的开创性研究探险的首席科学家,探险队首次在喜马拉雅山高海拔地区(5800 米)越冬。目前这部著作总结了 Pugh 在科学方面的贡献,这些贡献与他成功登上珠穆朗玛峰以及激励未来几代成功的研究人员进行高海拔研究有关。
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引用次数: 0
Merrem's Hump-Nosed Viper (Hypnale hypnale) Bite on the Tongue of an Infant Leading to Upper Airway Obstruction: An Unusual Presentation. Merrem's 驼鼻蝰 (Hypnale hypnale) 咬伤婴儿舌头导致上气道阻塞:一种不寻常的表现。
IF 1.4 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 Epub Date: 2024-05-10 DOI: 10.1177/10806032241252109
Chanaka Gunawardena, Hemal Samarathunga, Dayananda Bandara, Anuruddha Kiridena, Anjana Silva

Snakebites in unusual anatomical locations may lead to life-threatening consequences. Merrem's hump-nosed viper (Hypnale hypnale) is a medically important snake in Sri Lanka and India that causes many bites and envenomings. Their bites occur almost exclusively on upper and lower limbs and commonly result in local effects, with some patients developing systemic envenoming. No antivenom is available for treating envenoming by H. hypnale. We report an unusual case of H. hypnale bite on the tongue of a 10-month-old infant resulting in rapid local swelling of the tongue and floor of the mouth, requiring prompt intervention to prevent life-threatening upper airway obstruction. Early tracheostomy prevented upper airway obstruction and, along with supportive steroid therapy and antibiotics, led to a complete resolution of the local effects of the infant without permanent disability, despite the unavailability of antivenom.

在不寻常的解剖位置被蛇咬伤可能会导致危及生命的后果。Merrem's hump-nosed viper(Hypnale hypnale)是斯里兰卡和印度的一种重要医疗用蛇类,会造成许多咬伤和中毒。它们的咬伤几乎只发生在上肢和下肢,通常会造成局部影响,有些患者会出现全身中毒。目前还没有抗蛇毒血清可用于治疗 H. hypnale 导致的中毒。我们报告了一例不寻常的病例,一名 10 个月大的婴儿被 H. hypnale 咬伤舌头,导致舌头和口腔底部迅速局部肿胀,需要及时干预以防止危及生命的上呼吸道阻塞。尽管无法获得抗蛇毒血清,但早期的气管切开术防止了上呼吸道阻塞,并配合类固醇和抗生素的支持治疗,使婴儿的局部症状完全缓解,没有造成永久性残疾。
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引用次数: 0
Acute Coronary Syndrome at Altitude: Diagnostic Dilemma on Aconcagua Using Point-of-Care Ultrasound. 高海拔地区的急性冠状动脉综合征:在阿空加瓜岛使用护理点超声波诊断难题。
IF 1.4 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 Epub Date: 2024-05-08 DOI: 10.1177/10806032241249128
Chance Sullivan, Aaron Brillhart, Rodrigo J Duplessis, Ellen Stein, Sarah M Schlein

At the Plaza de Mulas medical tent, located at 4300 m (14,100 ft) along the Normal Route to the 6960 m (22,837 ft) summit of Aconcagua in Argentina, a Korean male in his 50s with no known medical conditions presented with lightheadedness and shortness of breath. He had taken sildenafil and acetazolamide that morning without improvement. Vital signs on arrival were notable for oxygen saturations in the high 60s with basilar crackles on lung auscultation, concerning for high altitude pulmonary edema. The patient was started on oxygen via nasal cannula and given dexamethasone. History was limited secondary to language barriers, but on review of systems the patient noted mild chest pressure. Bedside cardiac echocardiogram was performed, which revealed a septal wall motion abnormality. The patient was therefore given aspirin and clopidogrel and was flown to a lower trailhead, where he was met by local Emergency Medical Services. A 12-lead electrocardiogram revealed an anterior ST-elevation myocardial infarction, and the patient was taken emergently to the catheterization lab in Mendoza and underwent stent placement with a full recovery.

在位于阿根廷阿空加瓜海拔 6960 米(22837 英尺)山顶正常路线 4300 米(14100 英尺)处的 Plaza de Mulas 医疗帐篷里,一名 50 多岁的韩国男性出现了头晕目眩和呼吸急促的症状。他在当天早上服用了西地那非和乙酰唑胺,但情况没有改善。到达时生命体征显著,血氧饱和度在 60 多分,肺部听诊有基底噼啪声,这与高海拔肺水肿有关。患者开始通过鼻导管吸氧,并服用地塞米松。由于语言障碍,病史有限,但患者在复查系统时发现有轻微胸压。患者接受了床旁心脏超声心动图检查,结果显示室间隔壁运动异常。因此,医生给患者服用了阿司匹林和氯吡格雷,并将其送往较低的山路口,由当地的紧急医疗服务人员接机。12 导联心电图显示为前 ST 段抬高型心肌梗死,患者被紧急送往门多萨的导管室,接受了支架置入手术,并完全康复。
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引用次数: 0
The Outcome of Walking Cold Patients with Potential Mild Hypothermia to Safety-A Mountain Rescue Case Series. 将可能患有轻度体温过低的寒冷患者送至安全地带的结果--山地救援案例系列。
IF 1.4 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 Epub Date: 2024-06-14 DOI: 10.1177/10806032241259943
Mike Greene, Naomi Dodds, Les Gordon

Introduction: Some experts recommend that ambulant hypothermic patients should be rewarmed, fed, and not permitted to exercise for 30 min because of concerns that afterdrop can cause cardiac instability. We investigated the outcome of ambulant hypothermic patients in a case series from mountain rescue teams in Great Britain.

Methods: A questionnaire was used to collect information on a series of adult patients with a clinical diagnosis of mild hypothermia. All patients were alert on the AVPU scale and evacuated by walking from the mountain. The outcome measures were survival or a change in management because of medical deterioration during evacuation.

Results: A series of 108 eligible cases were reported over a 5-year period. When rescuers arrived on the scene, 98 (91%) patients were stationary, and 10 (9%) were still mobile. Thirty-eight (39%) of the stationary cases were walked immediately off the mountain without any on-scene delay. In the remaining 60 (61%) stationary cases, the decision was taken to delay evacuation to provide food, drinks, and additional clothing. In 3 cases, the use of heat packs indicated an intention to actively rewarm. In cases where the on-scene time was reported, 27 (79%) were known to be mobile again within 20 min. All patients survived, and no adverse medical events occurred in all 108 cases.

Conclusions: In this study, no adverse events occurred because of immediate mobilization, suggesting that in these cases, there appears to be minimal risk of early activity.

导言:由于担心体温下降后会导致心脏不稳定,一些专家建议对体温过低的卧床患者进行复温、喂食,并在 30 分钟内禁止其运动。我们在英国山地救援队的一个案例系列中调查了体温过低患者的救治结果:我们通过问卷调查收集了一系列临床诊断为轻度体温过低的成年患者的信息。所有患者均按照 AVPU 评分标准保持警觉,并以步行方式从山上撤离。结果以存活率或因撤离过程中病情恶化而改变治疗方案为衡量标准:结果:5 年内共报告了 108 例符合条件的病例。当救援人员到达现场时,98 名(91%)患者处于静止状态,10 名(9%)患者仍处于移动状态。在静止不动的病例中,有 38 人(39%)在没有任何现场延误的情况下立即步行下山。在其余 60 个(61%)静止病例中,决定延迟撤离,以便提供食物、饮料和额外衣物。在 3 个案例中,使用热敷袋表明了主动恢复体温的意图。在报告了现场时间的病例中,有 27 例(79%)患者在 20 分钟内恢复了行动能力。所有患者都存活了下来,所有108例患者都没有发生不良医疗事件:在这项研究中,没有人因为立即移动而发生不良事件,这表明在这些病例中,早期活动的风险似乎很小。
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引用次数: 0
Inappropriate Acetazolamide Use for a Hiker Who Developed Acute Kidney Injury. 为一名出现急性肾损伤的徒步旅行者不当使用乙酰唑胺。
IF 1.4 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 Epub Date: 2024-05-10 DOI: 10.1177/10806032241249452
Weston R Myers, Charles Bawcom, Cooper Schraudenbach, Brad L Bennett

Prophylactic use of acetazolamide (ACZ) to prevent acute mountain sickness (AMS) is a common practice among high altitude travelers and mountaineers. With its use comes a possible risk of acute kidney injury (AKI). We present a case in which a 56-year-old male hiker in Grand Canyon National Park developed acute exertional rhabdomyolysis and subsequent AKI while taking prophylactic ACZ to prevent AMS. This medication was prescribed despite the hiker encountering only moderate altitude at Grand Canyon with a planned descent within <24 h. The resulting AKI was determined to be the combined result of acute exertional rhabdomyolysis and dehydration/hypovolemia, with the ACZ, a diuretic, as a contributing factor. Medical providers need to recognize the risks/benefits with ACZ use for AMS prophylaxis and avoid prescribing it to individuals whose altitude exposure and activity fall outside the clinical practice guidelines recommended for use.

预防性使用乙酰唑胺(ACZ)来预防急性高山反应(AMS)是高海拔旅行者和登山者的常见做法。使用这种药物可能会带来急性肾损伤(AKI)的风险。我们介绍了这样一个病例:一名 56 岁的男性登山者在大峡谷国家公园服用预防性 ACZ 以预防急性登山病时,出现了急性劳累性横纹肌溶解症,随后引发了急性肾损伤(AKI)。尽管该徒步旅行者在大峡谷只遇到了中等海拔,并计划在
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引用次数: 0
Psychosocial Training Program for Lifeguards: A Pilot Study. 救生员社会心理培训计划:试点研究。
IF 1.4 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 Epub Date: 2024-05-20 DOI: 10.1177/10806032241252106
Paulo Santiago, Filipe Maia, Sandra Santiago, Daniel Duarte, Pedro Teques

Research has highlighted the need for training lifeguards in psychosocial skills. Therefore, this study aims to analyze the effectiveness of a short 10-h training program encompassing dimensions associated with emotional management, focus of attention, interpersonal relationships, and lifeguard behavior, and its effects on their psychosocial skills. A total of 64 lifeguards with experience ranging from 1 to 25 years (M = 5.93, SD = 6.07), randomly divided into experimental and control groups, participated in this study. The d2 Test of Attention, the Social Intelligence Test of O'Sullivan and Guilford, and the MSCEIT Emotional Intelligence Test were used to assess psychosocial skills. A multivariate analysis of variance for repeated measures (2 × 3 (Group × Time) MANOVA) was performed to analyze the effects of the training program on psychosocial skills. The results revealed that the experimental group showed statistically significant improvements in focus of attention and emotional intelligence compared to the control group. However, it is worth noting that no statistically significant group interactions were observed for measures of social intelligence. Taken together, these results seem to highlight the importance of including psychosocial content in the general training of lifeguards.

研究强调了对救生员进行社会心理技能培训的必要性。因此,本研究旨在分析一个为期 10 小时的短期培训项目的有效性,该培训项目包括情绪管理、注意力集中、人际关系和救生员行为等方面,以及该培训项目对救生员社会心理技能的影响。共有 64 名救生员参加了这项研究,他们的工作经验从 1 年到 25 年不等(男 = 5.93,女 = 6.07),被随机分为实验组和对照组。实验组采用 d2 注意力测验、奥沙利文和吉尔福德社会智力测验以及 MSCEIT 情商测验来评估救生员的社会心理技能。采用重复测量的多元方差分析(2×3(组×时间)MANOVA)来分析培训项目对社会心理技能的影响。结果显示,与对照组相比,实验组在注意力集中和情商方面有显著的统计学进步。然而,值得注意的是,在社会智能的测量方面,没有观察到具有统计学意义的组间交互作用。综上所述,这些结果似乎突出了在救生员的一般培训中加入社会心理内容的重要性。
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引用次数: 0
Polar Thigh and Other Medical Observations During the Longest Solo Unsupported One-Way Polar Ski Expedition in Antarctica. 南极洲最长的单人无支撑单向极地滑雪探险中的极地大腿和其他医学观察。
IF 1.4 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 Epub Date: 2024-06-09 DOI: 10.1177/10806032241253817
Volker Scheer, Harpreet Chandi, Encarna Valero, Mathias Steinach

Antarctic expeditions are exceptional challenges for the human body, and medical issues such as nutritional deficiencies, polar anemia, cold injuries, and even death have been reported. We prospectively investigated medical issues encountered by a 33-year-old female adventurer completing the longest solo unsupported one-way polar ski expedition in Antarctica, covering 1484.53 km in 70 days and 16 h from Hercules Inlet to the Ross Ice Shelf, in temperatures estimated from -12 to -50°C and wind speeds of up to 60 mi/h. The adventurer developed a debilitating overuse musculoskeletal neck injury due to poor environmental conditions (ie, poor visibility, wind, and soft snow) while pulling a heavy sled and continuously holding the neck in a flexed position for checking directions on a mounted compass. The adventurer further developed a cold injury on the left calf (polar thigh) that gradually worsened and became ulcerated and more painful throughout the expedition. Potential risk factors included cold ambient temperatures, exposure to windy conditions, and clothing. After the expedition, this injury was treated with a skin graft. Important changes in body mass were observed (ie, reduction of body mass by 26.7% after the expedition) as well as general fatigue, muscle soreness, and sleep deterioration. This case study contributes to the body of knowledge of medical issues during Antarctic expeditions and provides the first scientific account of an adventurer with polar thigh. Further research into this condition is recommended.

南极探险是对人体的特殊挑战,营养不良、极地贫血、冷伤甚至死亡等医疗问题时有报道。我们对一名 33 岁的女探险家在南极洲完成最长的单人无支撑单向极地滑雪探险时遇到的医疗问题进行了前瞻性调查,该探险家在 70 天 16 小时内完成了从赫拉克勒斯海湾到罗斯冰架的 1484.53 公里的行程,当时的气温估计在零下 12 到零下 50 摄氏度之间,风速高达 60 英里/小时。由于恶劣的环境条件(即能见度低、风大、雪软),冒险者在拉着沉重的雪橇并持续保持颈部弯曲的姿势,以便在安装的指南针上查看方向时,颈部肌肉骨骼过度劳损。探险者的左小腿(极地大腿)还受了冷伤,并在整个探险过程中逐渐恶化、溃烂和疼痛。潜在的危险因素包括寒冷的环境温度、暴露在大风环境中以及衣服。探险结束后,对这一损伤进行了植皮治疗。观察到身体质量发生了重要变化(即远征后身体质量减少了 26.7%),并出现了全身疲劳、肌肉酸痛和睡眠质量下降等症状。本病例研究有助于了解南极探险期间的医疗问题,并首次对患有极地大腿的探险家进行了科学描述。建议对这种病症进行进一步研究。
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引用次数: 0
Kea: The "Cheeky" Alpine Parrot. 凯亚厚脸皮 "高山鹦鹉
IF 1.4 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 Epub Date: 2024-05-01 DOI: 10.1177/10806032241248621
Dale R Wagner
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引用次数: 0
Fab Antivenom Reversal of Neurotoxicity Caused by a Juvenile Crotalus horridus Lacking Canebrake Toxin. Fab抗蛇毒血清可逆转由缺乏眼镜蛇毒素的幼年眼镜蛇引起的神经中毒。
IF 1.4 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 Epub Date: 2024-06-05 DOI: 10.1177/10806032241253823
Stefanie Musick, Nathaniel Mann, Mark J Margres, Shantal S Solis Solis, Chris Parkinson

We present a case of neurotoxic effects in a pediatric patient after envenomation by a timber rattlesnake (Crotalus horridus) in the Appalachian upstate of South Carolina. Though some members of this species are capable of primarily neurotoxic envenomation, there is heterogeneity in venom composition, and neurotoxic timber rattlesnakes are not endemic to the Appalachian region. However, neurotoxic effects caused by C horridus species lacking typical neurotoxins have been suspected, though not previously confirmed in the medical literature. This case presents a patient who was envenomated by a genotypically confirmed non-neurotoxic C horridus but who nevertheless presented with symptoms consistent with primary neurotoxicity. Neurotoxic effects can be variable in their response to traditional antivenom, though this patient demonstrated rapid response to treatment, representing a novel case in the literature of neurotoxic effects from a snake lacking typical neurotoxins with documented improvement with traditional antivenom.

我们介绍了一例在南卡罗来纳州阿巴拉契亚高地被木材响尾蛇(Crotalus horridus)咬伤的小儿患者的神经中毒病例。虽然该物种的某些成员能够主要造成神经毒性毒液中毒,但毒液成分存在异质性,而且具有神经毒性的木材响尾蛇并非阿巴拉契亚地区的特有物种。然而,人们一直怀疑缺乏典型神经毒素的C horridus物种会造成神经毒性影响,但此前并未在医学文献中得到证实。本病例中的患者被一种经基因型确认无神经毒性的角蝰毒倒,但却出现了与原发性神经中毒症状一致的症状。神经毒性效应对传统抗蛇毒血清的反应不一,但该患者对治疗反应迅速,是文献中缺乏典型神经毒素的蛇类引起神经毒性效应的新病例,传统抗蛇毒血清治疗后症状明显好转。
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引用次数: 0
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