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Early-stage voiding function following uni- versus bilateral inferior vesical vessel resection during therapeutic lateral lymph node dissection with autonomic nerve sparing for advanced low rectal cancer (with video) 晚期低位直肠癌治疗性侧淋巴结清扫术中进行单侧与双侧下膀胱血管切除术并保留自主神经后的早期排尿功能(附视频)
IF 1.7 4区 医学 Q2 SURGERY Pub Date : 2024-06-17 DOI: 10.5114/wiitm.2024.140318
Hongjie Yang, Peishi Jiang, Zhichun Zhang, Jiafei Liu, Yuanda Zhou, Peng Li, Qingsheng Zeng, Yu Long, Xipeng Zhang, Yi Sun
Introduction
Lateral lymph node dissection (LLND) has now been widely accepted as the optimal procedure to minimize lateral local recurrence (LLR) for selected cases with advanced lower rectal cancer in Asian countries. However, there is still controversy over the preservation or resection of the inferior vesical vessels (IVVs) during LLND due to concerns of impaired post-operative urinary function. Moreover, the standardized procedure for autonomic nerve preservation has not yet been established.

Aim
To evaluate the early-stage postoperative voiding function in patients who underwent LLND with uni- versus bilateral resection of the IVVs and to introduce an autonomic nerve sparing technique with a fascial space priority approach (FSPA).

Material and methods
LLND was performed in 106 consecutive patients with advanced low rectal cancer at Tianjin Union Medical Center from May 2017 to October 2022. Prospectively collected clinical data were retrospectively compared between patients who received uni-lateral and bilateral LLND. A video with narration was provided to introduce the stepwise procedure of autonomic nerve preservation during IVV resection.

Results
The unilateral lymph node dissection (LND) group and the bilateral LND group included 75 and 31 cases, respectively. All LLNDs were performed with FSPA with IVV resection as a standard procedure. No significant differences were observed in overall catheterization days (p = 0.336) and re-catheterization rate (p = 0.575) between groups. No patients in either group suffered from long-term (≥ 30 days) voiding dysfunction.

Conclusions
Autonomic nerve sparing is achievable with resection of IVVs during LLND. Satisfactory early-stage voiding function could be obtained with IVV resection on both sides.

导言在亚洲国家,侧淋巴结清扫术(LLND)已被广泛接受为减少晚期下段直肠癌侧局部复发(LLR)的最佳手术方法。然而,由于担心术后排尿功能受损,在 LLND 过程中保留或切除下膀胱血管(IVV)仍存在争议。材料和方法2017年5月至2022年10月,天津协和医院连续为106例晚期低位直肠癌患者实施了LLND。回顾性比较了前瞻性收集的单侧和双侧 LLND 患者的临床数据。结果 单侧淋巴结清扫(LND)组和双侧LND组分别包括75例和31例患者。所有LLND均采用FSPA进行,并将IVV切除术作为标准手术。两组患者的总导管插入天数(P = 0.336)和再次导管插入率(P = 0.575)无明显差异。两组患者均未出现长期(≥ 30 天)排尿功能障碍。结论LLND术中切除IVV可达到保留自主神经的目的,通过切除两侧IVV可获得满意的早期排尿功能。
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引用次数: 0
Effect and prognosis of endoscopic intracranial hematoma removal and hematoma puncture and drainage in patients with hypertensive intracerebral hemorrhage 内镜下颅内血肿清除术和血肿穿刺引流术对高血压性脑出血患者的影响和预后
IF 1.7 4区 医学 Q2 SURGERY Pub Date : 2024-06-17 DOI: 10.5114/wiitm.2024.140613
Yi Xiao, Renping Wang
Introduction
Hypertensive intracerebral hemorrhage is one of the most serious complications of hypertension. The treatment focuses on reducing bleeding damage and promoting functional recovery.

Aim
This study investigated the efficacy and prognosis of endoscopic intracranial hematoma removal (EIHR) and hematoma puncture and drainage (HPD) in treating hypertensive intracerebral hemorrhage (HICH).

Material and methods
Ninety-two patients admitted to our hospital for EIHR and HPD between September 30, 2021 and September 30, 2022 were enrolled, including 14 cases of EIHR (endoscopy group) and 78 cases of HPD (puncture group). The efficacy of the two surgery modes in treating HICH patients was compared. Univariate logistic regression (ULR) and multivariate logistic regression (MLR) were employed to analyze the influences of different treatment methods on the prognosis of patients with HICH.

Results
The average hematoma clearance rate (HCR) of all patients was 80.52%, and the patients in the endoscopy group had a higher HCR than those in the puncture group (73.00% vs. 86.00%) (p < 0.001). The good prognosis rate (GPR) shown by the Glasgow Outcome Scale (GOS) score in the endoscopy group was 69.23%, and that in the puncture group was 40.38%, a large but statistically non-significant difference (p > 0.05).

Conclusions
The HCR of EIHR was greatly higher based on that of HPD, but showed no great difference in prognostic effect. The higher the GCS score on admission, the lower the likelihood of poor prognosis.

导言高血压脑出血是高血压最严重的并发症之一,治疗重点是减少出血损伤和促进功能恢复。目的 探讨内镜下颅内血肿清除术(EIHR)和血肿穿刺引流术(HPD)治疗高血压性脑出血(HICH)的疗效和预后。材料与方法选取2021年9月30日至2022年9月30日期间我院收治的92例EIHR和HPD患者作为研究对象,其中EIHR(内镜组)14例,HPD(穿刺组)78例。比较了两种手术方式治疗 HICH 患者的疗效。结果所有患者的平均血肿清除率(HCR)为80.52%,内镜组患者的HCR高于穿刺组(73.00% vs. 86.00%)(P <0.001)。结论 EIHR的HCR在HPD的基础上大大提高,但在预后效果上没有太大差异。入院时 GCS 评分越高,预后不良的可能性越低。
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引用次数: 0
Outcomes of minimally invasive surgery for pulmonary metastasis: who benefits the most? 肺转移瘤微创手术的疗效:谁受益最大?
IF 1.7 4区 医学 Q2 SURGERY Pub Date : 2024-06-17 DOI: 10.5114/wiitm.2024.140300
Burcu Kılıç, Ömer Faruk Sağlam, Levani Chikvaidzade, Ezel Erşen, Hasan Kara, Akif Turna, Kamil Kaynak, Ahmet Demirkaya
Introduction
Metastatic disease is one of the main causes of death and factors affecting overall survival. It is known that selected patients with pulmonary oligometastases whose primary tumor is under control and who have adequate respiratory capacity may benefit from metastasectomy by resecting all detected lesions.

Aim
To report our findings on the use of video-assisted thoracoscopic surgery (VATS) for pulmonary metastasectomy, with a focus on identifying suitable candidates.

Material and methods
Between August 2010 and 2023 a total of 532 pulmonary metastasectomy procedures were performed in our institution. Metastasectomy was performed with VATS for 281 of those patients.

Results
VATS metastasectomy was performed in 131 patients with a single lesion on preoperative imaging, while 110 patients underwent metastasectomy for multiple lesions. The rate was significantly (p < 0.05) lower in the group with multiple lesions removed during surgery (38 months) than in the group with only one lesion removed during surgery (60 months). The predicted survival time in the group with other tumor histology (79 months) was significantly (p < 0.05) higher than in the groups with tumor histology carcinoma (41.4 months) and sarcoma (55.5 months).

Conclusions
The best prognosis after metastasectomy is provided in cases with a single nodule. Grade is also an important prognostic factor affecting survival, particularly for grade 1 tumor. The histopathological type of the primary tumor is also a significant prognostic factor affecting survival after pulmonary metastasectomy in secondary pulmonary neoplasms, particularly for sarcoma and carcinoma.

导言转移性疾病是导致死亡的主要原因之一,也是影响总生存率的因素之一。据了解,经过筛选的肺寡转移患者,如果其原发肿瘤得到控制且有足够的呼吸能力,可通过切除所有发现的病灶而从转移灶切除术中获益。材料和方法2010年8月至2023年期间,我院共进行了532例肺转移灶切除术,其中281例患者使用VATS进行了转移灶切除术。其中 281 例患者采用 VATS 进行转移瘤切除术。结果131 例术前造影显示为单发病灶的患者接受了 VATS 转移瘤切除术,110 例患者因多发病灶接受了转移瘤切除术。手术中切除多个病灶组的存活率(38 个月)明显低于手术中仅切除一个病灶组(60 个月)(P < 0.05)。其他肿瘤组织学组的预测生存期(79 个月)明显(p < 0.05)高于肿瘤组织学为癌(41.4 个月)和肉瘤(55.5 个月)的组别。分级也是影响生存期的重要预后因素,尤其是 1 级肿瘤。原发肿瘤的组织病理学类型也是影响继发性肺肿瘤肺转移切除术后生存率的重要预后因素,尤其是肉瘤和癌。
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引用次数: 0
Meta-analysis of clinical efficacy and safety of transanal endoscopic microsurgery and endoscopic submucosal dissection in the treatment of rectal tumors 经肛门内镜显微手术和内镜黏膜下剥离术治疗直肠肿瘤的临床疗效和安全性的元分析
IF 1.7 4区 医学 Q2 SURGERY Pub Date : 2024-05-27 DOI: 10.5114/wiitm.2024.139984
Jin Yao, Yongshen Fan
Aim
The aim of the article was to systematically evaluate the clinical efficacy and safety of transanal endoscopic microsurgery (TEM) and endoscopic submucosal dissection (ESD) in the treatment of rectal tumors.

Material and methods
Control studies were conducted on cases included in the electronic databases Medline, Embase, Cochrane Library, and CNKI. Patients with colorectal tumors were included in the TEM and ESD groups for treatment, with the main indicators being R0 resection rate, postoperative perforation and bleeding incidence, and tumor recurrence rate. The meta-analysis was carried out using RevMan 5.3 software.

Results
A total of 10 studies were included, with 736 patients. The analysis showed that for the recurrence rate in the TEM group compared to ESD, OR = 1.23, 95% CI = 0.56–2.72, p = 0.60; for the R0 resection rate between the TEM group and ESD group, OR = 1.35, 95% CI = 0.82–2.22, p = 0.24; for the incidence of perforation in the TEM and ESD groups, OR = 0.59, 95% CI = 0.25–1.40, p = 0.23. The inter-group comparison of these three items was statistically significant. Compared with the ESD group, the hospitalization time and the incidence of bleeding of the TEM group were both lower, with SD = 0.48, 95% CI = 0.26–0.69, p < 0.001 and OR = 0.35, 95% CI = 0.13–0.92, p = 0.03. The differences were statistically significant.

Conclusions
Both TEM and ESD endoscopic treatment techniques can achieve a higher R0 resection rate and lower risk of tumor recurrence in the treatment of colorectal tumors. However, TEM may have higher surgical safety than ESD technology, and can shorten postoperative hospitalization time and lower postoperative bleeding rate.

材料和方法对电子数据库 Medline、Embase、Cochrane Library 和 CNKI 中收录的病例进行对照研究。将结直肠肿瘤患者纳入TEM组和ESD组进行治疗,主要指标为R0切除率、术后穿孔和出血发生率以及肿瘤复发率。荟萃分析使用 RevMan 5.3 软件进行。分析结果显示,TEM组与ESD组的复发率比较,OR=1.23,95% CI=0.56-2.72,P=0.60;TEM组与ESD组的R0切除率比较,OR=1.35,95% CI=0.82-2.22,P=0.24;TEM组与ESD组的穿孔发生率比较,OR=0.59,95% CI=0.25-1.40,P=0.23。这三个项目的组间比较具有统计学意义。与 ESD 组相比,TEM 组的住院时间和出血发生率均较低,SD = 0.48,95% CI = 0.26-0.69,p < 0.001,OR = 0.35,95% CI = 0.13-0.92,p = 0.03。结论在结直肠肿瘤的治疗中,TEM 和 ESD 内镜治疗技术都能达到较高的 R0 切除率和较低的肿瘤复发风险。但 TEM 的手术安全性可能高于 ESD 技术,且能缩短术后住院时间,降低术后出血率。
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引用次数: 0
Clinical comparative study of laparoscopic partial splenectomy and open partial splenectomy 腹腔镜脾脏部分切除术与开腹脾脏部分切除术的临床对比研究
IF 1.7 4区 医学 Q2 SURGERY Pub Date : 2024-05-27 DOI: 10.5114/wiitm.2024.139988
Shuming Zeng, Weiwei Wang, Wenying Chen, Jianbo Xiao
Introduction
The aim of the article was too investigate and compare the feasibility, safety, and early postoperative recovery associated with laparoscopic partial splenectomy (LPS) and open partial splenectomy (OPS) in patients with benign splenic tumours and traumatic splenic rupture.

Material and methods
A retrospective analysis was conducted on clinical data from 110 patients undergoing splenic resection at our hospital between March 2019 and May 2022. Among them, 35 patients underwent OPS, 25 underwent LPS for traumatic splenic rupture, while 50 patients with benign splenic tumours underwent either OPS (n = 20) or LPS (n = 30). Preoperative, intraoperative, and postoperative data were collected and compared. Statistical analysis was conducted using SPSS software.

Results
There was no significant difference in the general data between the 2 groups of patients with benign splenic tumours and those with splenic trauma. Among patients with traumatic splenic rupture, the OPS group had a shorter operation time (p < 0.05). Regardless of whether they had traumatic splenic rupture or benign splenic tumours, the LPS group required less postoperative analgesia and had a shorter defecation recovery time (p < 0.05). Additionally, the LPS group displayed lower white blood cell count, white blood cell/lymphocyte ratio (WLR), neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR), C-reactive protein (CRP), calcitonin (PCT), and interleukin-6 (IL-6) than the OPS group on the first and third days post-surgery (p < 0.05).

Conclusions
In comparison to OPS, LPS presents significant advantages, including minimal surgical trauma, a reduced early postoperative inflammatory response, milder wound pain, and a faster recovery of gastrointestinal function.

引言 本文旨在研究和比较腹腔镜脾部分切除术(LPS)和开腹脾部分切除术(OPS)在良性脾肿瘤和外伤性脾破裂患者中的可行性、安全性和术后早期恢复情况。其中,35 例患者接受了 OPS,25 例患者因外伤性脾破裂接受了 LPS,50 例良性脾肿瘤患者接受了 OPS(n = 20)或 LPS(n = 30)。对术前、术中和术后数据进行了收集和比较。结果两组脾良性肿瘤患者和脾外伤患者的一般数据无明显差异。在外伤性脾破裂患者中,OPS 组的手术时间更短(P < 0.05)。不管是外伤性脾破裂还是良性脾肿瘤,LPS 组术后镇痛需求更少,排便恢复时间更短(p < 0.05)。此外,LPS 组在术后第一天和第三天的白细胞计数、白细胞/淋巴细胞比值(WLR)、中性粒细胞/淋巴细胞比值(NLR)、单核细胞/淋巴细胞比值(MLR)、C 反应蛋白(CRP)、降钙素原(PCT)和白细胞介素-6(IL-6)均低于 OPS 组(P < 0.05)。结论与 OPS 相比,LPS 具有显著优势,包括手术创伤小、术后早期炎症反应轻、伤口疼痛轻、胃肠功能恢复快。
{"title":"Clinical comparative study of laparoscopic partial splenectomy and open partial splenectomy","authors":"Shuming Zeng, Weiwei Wang, Wenying Chen, Jianbo Xiao","doi":"10.5114/wiitm.2024.139988","DOIUrl":"https://doi.org/10.5114/wiitm.2024.139988","url":null,"abstract":"<b>Introduction</b><br/>The aim of the article was too investigate and compare the feasibility, safety, and early postoperative recovery associated with laparoscopic partial splenectomy (LPS) and open partial splenectomy (OPS) in patients with benign splenic tumours and traumatic splenic rupture.<br/><br/><b>Material and methods</b><br/>A retrospective analysis was conducted on clinical data from 110 patients undergoing splenic resection at our hospital between March 2019 and May 2022. Among them, 35 patients underwent OPS, 25 underwent LPS for traumatic splenic rupture, while 50 patients with benign splenic tumours underwent either OPS (n = 20) or LPS (n = 30). Preoperative, intraoperative, and postoperative data were collected and compared. Statistical analysis was conducted using SPSS software.<br/><br/><b>Results</b><br/>There was no significant difference in the general data between the 2 groups of patients with benign splenic tumours and those with splenic trauma. Among patients with traumatic splenic rupture, the OPS group had a shorter operation time (p &lt; 0.05). Regardless of whether they had traumatic splenic rupture or benign splenic tumours, the LPS group required less postoperative analgesia and had a shorter defecation recovery time (p &lt; 0.05). Additionally, the LPS group displayed lower white blood cell count, white blood cell/lymphocyte ratio (WLR), neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR), C-reactive protein (CRP), calcitonin (PCT), and interleukin-6 (IL-6) than the OPS group on the first and third days post-surgery (p &lt; 0.05).<br/><br/><b>Conclusions</b><br/>In comparison to OPS, LPS presents significant advantages, including minimal surgical trauma, a reduced early postoperative inflammatory response, milder wound pain, and a faster recovery of gastrointestinal function.<br/><br/>","PeriodicalId":49361,"journal":{"name":"Videosurgery and Other Miniinvasive Techniques","volume":"172 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141508873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endoscopic sleeve gastroplasty safety profile – retrospective, single-center analysis of 222 consecutive patients including the learning curve period 内镜袖带胃成形术安全性概况--对 222 名连续患者(包括学习曲线期)的回顾性单中心分析
IF 1.7 4区 医学 Q2 SURGERY Pub Date : 2024-05-15 DOI: 10.5114/wiitm.2024.139687
Przemysław Kasprzyk, Kamila Wysocka-Konieczna, Matylda Sobczak, Michał Spychalski
Introduction
The global obesity epidemic affects over 1.9 billion adults, with an additional 650 million classified as obese. Endoscopic sleeve gastroplasty (ESG) is a type of minimally invasive endobariatric procedure. It is a less invasive alternative to laparoscopic sleeve gastrectomy (LSG). Although the effectiveness of ESG is lower, it might have a better safety profile.

Aim
To assess the safety profile of ESG and describe complications classified as grade II or higher, using the Clavien-Dindo classification, with an overview of the learning curve.

Material and methods
We included 222 patients who underwent ESG at the Endoscopic and Bariatric Surgery Center of the hospital in Brzeziny from January 2021 to October 2023. The severity of complications was evaluated based on the Clavien-Dindo classification, considering complications of grade II or higher.

Results
Among the studied group of patients, a total of 4 (1.8%) cases of perioperative bleeding into the gastrointestinal tract were recorded. One (0.5%) patient had the most severe grade IVb complication that required treatment in the Intensive Care Unit. All patients with serious adverse events (SAE) fully recovered. We did not observe an association between the learning curve, procedure duration, and the frequency or severity of postoperative complications.

导言:全球有超过 19 亿成年人受到肥胖症的影响,另有 6.5 亿人被归类为肥胖症。内镜袖状胃成形术(ESG)是一种微创减肥手术。它是腹腔镜袖状胃切除术(LSG)的微创替代手术。材料和方法我们纳入了 2021 年 1 月至 2023 年 10 月期间在 Brzeziny 医院内镜和减肥手术中心接受 ESG 手术的 222 名患者。并发症的严重程度根据克拉维恩-丁多(Clavien-Dindo)分类法进行评估,并考虑二级或二级以上并发症。一名患者(0.5%)出现了最严重的 IVb 级并发症,需要在重症监护室接受治疗。所有发生严重不良事件(SAE)的患者均已完全康复。我们没有观察到学习曲线、手术持续时间与术后并发症的频率或严重程度之间存在关联。
{"title":"Endoscopic sleeve gastroplasty safety profile – retrospective, single-center analysis of 222 consecutive patients including the learning curve period","authors":"Przemysław Kasprzyk, Kamila Wysocka-Konieczna, Matylda Sobczak, Michał Spychalski","doi":"10.5114/wiitm.2024.139687","DOIUrl":"https://doi.org/10.5114/wiitm.2024.139687","url":null,"abstract":"<b>Introduction</b><br/>The global obesity epidemic affects over 1.9 billion adults, with an additional 650 million classified as obese. Endoscopic sleeve gastroplasty (ESG) is a type of minimally invasive endobariatric procedure. It is a less invasive alternative to laparoscopic sleeve gastrectomy (LSG). Although the effectiveness of ESG is lower, it might have a better safety profile.<br/><br/><b>Aim</b><br/>To assess the safety profile of ESG and describe complications classified as grade II or higher, using the Clavien-Dindo classification, with an overview of the learning curve.<br/><br/><b>Material and methods</b><br/>We included 222 patients who underwent ESG at the Endoscopic and Bariatric Surgery Center of the hospital in Brzeziny from January 2021 to October 2023. The severity of complications was evaluated based on the Clavien-Dindo classification, considering complications of grade II or higher.<br/><br/><b>Results</b><br/>Among the studied group of patients, a total of 4 (1.8%) cases of perioperative bleeding into the gastrointestinal tract were recorded. One (0.5%) patient had the most severe grade IVb complication that required treatment in the Intensive Care Unit. All patients with serious adverse events (SAE) fully recovered. We did not observe an association between the learning curve, procedure duration, and the frequency or severity of postoperative complications.<br/><br/>","PeriodicalId":49361,"journal":{"name":"Videosurgery and Other Miniinvasive Techniques","volume":"34 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141508874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Femoro-popliteal endovascular interventions 股骨头血管内介入治疗
IF 1.7 4区 医学 Q2 SURGERY Pub Date : 2024-05-10 DOI: 10.5114/wiitm.2024.139548
Azat Chinaliyev, Samat Saparbayev, Bazylbek Zhakiyev, Gulinur Chinaliyeva, Didar Khassenov, Irlan Sagandykov, Ibrahim A. Abdelazim, Ainur Donayeva, Ainur Amanzholkyzy, Batyrbek Alibekov, Luis Arias, Nazgul Dzhantemirova, Zhenisbek Baubekov, Bibigul Karimsakova
Peripheral artery disease (PAD) is a worldwide major health challenge, and it is a strong predictor of mortality and morbidity. The advances in PAD treatment have resulted in many therapeutic options or endovascular interventions (EVIs) for endovascular revascularization if drug therapy does not lead to substantial improvement. Randomized controlled trials (RCTs) have reported the efficacy of various EVIs such as atherectomy, stents, and medicated balloons over the traditional transluminal angioplasty; however, the standard treatment for PAD remains unclear due to the lack of head-to-head comparative studies between different EVIs. Additionally, the variable outcomes between clinical trials regarding the functional capacity and quality of life (QoL) make it difficult to ascertain the superiority of one particular EVI over another. Therefore, the latest PAD clinical trials should include head-to-head comparisons between different EVIs, and this review aimed to highlight the femoro-popliteal EVIs, evidence supporting each intervention and why those EVIs are used.
外周动脉疾病(PAD)是世界性的重大健康挑战,也是预测死亡率和发病率的重要指标。随着外周动脉疾病治疗技术的不断进步,出现了许多治疗方案或血管内介入疗法(EVIs),如果药物治疗不能带来实质性改善,则可进行血管内血运重建。随机对照试验(RCT)显示,与传统的腔内血管成形术相比,动脉粥样硬化切除术、支架和药物球囊等各种血管内介入治疗具有一定的疗效;但是,由于缺乏不同血管内介入治疗之间的头对头比较研究,PAD 的标准治疗方法仍不明确。此外,不同临床试验在功能能力和生活质量(QoL)方面的结果也不尽相同,因此很难确定某一种 EVI 是否优于另一种 EVI。因此,最新的 PAD 临床试验应包括不同 EVI 之间的头对头比较,本综述旨在强调股骨干 EVI、支持每种干预措施的证据以及使用这些 EVI 的原因。
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引用次数: 0
Efficacy and safety of enteral nutrition in prone position among critically ill ventilated patients: a meta-analysis 重症呼吸机患者俯卧位肠内营养的有效性和安全性:荟萃分析
IF 1.7 4区 医学 Q2 SURGERY Pub Date : 2024-05-08 DOI: 10.5114/wiitm.2024.139473
An Yong, Xinxin Li, Lili Peng, Shouzhen Cheng, Wen Qiu
Introduction
Prone positioning in critical care units may reduce mortality in specific patients who have been admitted with severe conditions.

Aim
The current meta-analysis aims to assess the impact of prone compared to supine position besides the safety and tolerability of different enteral feeding techniques in critically ill patients regarding mortality, pneumonia, aspiration, and vomiting.

Material and methods
A systematic literature search found 25 relevant trials involving 1984 participants at the start of the study. Statistical analysis using the dichotomous analysis methods was used within the fixed model to calculate the odds ratio (OR) with 95% confidence intervals (CIs).

Results
In comparison with the post-pyloric nutrition group, gastric feeding had no significant impact on the mortality rate (OR = 1; 95% CI: 0.76–1.32). While the findings showed a significantly higher incidence of pneumonia with gastric feeding compared with post-pyloric nutrition (OR = 1.92; 95% CI: 1.43–-2.57), there was no significant difference regarding pulmonary aspiration and vomiting (OR = 1.41; 95% CI: 0.75–2.65 and OR = 0.92; 95% CI:, 0.66–1.27, respectively). Reflux gastric content was significantly higher with gastric nutrition (OR = 8.23; 95% CI: 2.43–27.89).

Conclusions
From reduced gastrointestinal events to significantly higher vomiting rates, prone position during enteral feeding showed mixed effects. Post-pyloric feeding is more tolerated and safer compared with gastric feeding. The mortality rate is not significantly different between techniques.

导言重症监护病房中的俯卧位可降低因病情严重而入院的特定患者的死亡率.目的目前的荟萃分析旨在评估俯卧位与仰卧位相比,除了对重症患者不同肠道喂养技术的安全性和耐受性有影响外,还对死亡率、肺炎、吸入和呕吐有影响.材料和方法系统性文献检索发现了 25 项相关试验,在研究开始时有 1984 名参与者.结果与幽门后营养组相比,胃喂养对死亡率没有显著影响(OR = 1;95% CI:0.76-1.32)。研究结果表明,与幽门后营养组相比,胃喂养组的肺炎发病率明显更高(OR = 1.92;95% CI:1.43--2.57),但肺吸入和呕吐方面没有明显差异(OR = 1.41;95% CI:0.75-2.65 和 OR = 0.92;95% CI:0.66-1.27)。结论从减少胃肠道事件到显著增加呕吐率,肠内喂养时俯卧位的效果好坏参半。与胃喂养相比,幽门后喂养更容易耐受,也更安全。不同技术的死亡率没有明显差异。
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引用次数: 0
Disparities of tumour markers in intraperitoneal drainage fluid between laparoscopic and open radical gastrectomy for gastric cancer 腹腔镜胃癌根治术与开腹胃癌根治术腹腔引流液中肿瘤标志物的差异
IF 1.7 4区 医学 Q2 SURGERY Pub Date : 2024-05-08 DOI: 10.5114/wiitm.2024.139509
Jian Guo, Longzhi Zheng, Junwei Chen, Wei Lin
Introduction
Despite the remarkable progress in minimally invasive surgery, the potential association between laparoscopic gastrectomy and the risk of peritoneal metastasis remains uncertain.

Aim
To investigate variations in tumour markers in intraperitoneal drainage fluid between laparoscopic radical gastrectomy and open radical gastrectomy for gastric cancer.

Material and methods
A total of 106 patients diagnosed with gastric cancer between July 2018 and November 2020 were included in this study, 45 of whom underwent laparoscopic radical gastrectomy (laparoscopic group) and 61 underwent open radical gastrectomy (open group). Variations in the levels of carcinoembryonic antigen (CEA), cancer antigen 125 (CA125), cancer antigen 199 (CA199), and α-fetoprotein (AFP) in the intraperitoneal drainage fluid were compared and analysed on postoperative days (PODs) 1, 2, 3, and 5 between the two groups. Additionally, the postoperative 3-year survival rates between the two groups were compared and analysed.

Results
No significant differences in CEA, CA199, and AFP levels in the intraperitoneal drainage fluid were observed between the two groups on postoperative days (PODs) 1, 2, 3, and 5 (p > 0.05). However, the level of CA125 in the intraperitoneal drainage fluid of the laparoscopic group was notably higher than that of the open group on POD 2 (p < 0.05); however, there were no significant differences between the two groups on PODs 1, 3, and 5 (p > 0.05). There was no significant difference in the 3-year postoperative survival rates between the two groups.

Conclusions
There were no significant differences in CEA, CA125, CA199, and AFP levels in the intraperitoneal drainage fluid between laparoscopic radical gastrectomy and open radical gastrectomy for gastric cancer, confirming from another perspective that laparoscopic radical gastrectomy does not increase the risk of intraperitoneal metastasis.

引言尽管微创手术取得了显著进展,但腹腔镜胃切除术与腹膜转移风险之间的潜在关联仍不确定。目的研究腹腔镜胃癌根治术与开腹胃癌根治术腹腔引流液中肿瘤标志物的变化。材料和方法本研究共纳入2018年7月至2020年11月期间确诊的106例胃癌患者,其中45例接受腹腔镜胃根治术(腹腔镜组),61例接受开腹胃根治术(开腹组)。比较并分析了两组患者在术后第1、2、3和5天(POD)腹腔引流液中癌胚抗原(CEA)、癌抗原125(CA125)、癌抗原199(CA199)和α-胎儿蛋白(AFP)水平的变化。结果在术后第 1、2、3 和 5 天(PODs),两组腹腔引流液中的 CEA、CA199 和 AFP 水平无明显差异(P > 0.05)。然而,腹腔镜组腹腔引流液中的 CA125 水平在 POD 2 明显高于开腹组(p <;0.05);但在 POD 1、3 和 5 两组间无显著差异(p >;0.05)。结论腹腔镜胃癌根治术与开腹胃癌根治术腹腔引流液中的CEA、CA125、CA199和AFP水平无明显差异,从另一个角度证实了腹腔镜胃癌根治术不会增加腹膜内转移的风险。
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引用次数: 0
Preoperative computed tomography-guided localization for pulmonary nodules: a randomized controlled trial of coil and anchored needle localization 术前计算机断层扫描引导下的肺结节定位:线圈和锚定针定位的随机对照试验
IF 1.7 4区 医学 Q2 SURGERY Pub Date : 2024-04-24 DOI: 10.5114/wiitm.2024.139198
Ya-Nan Lv, Wen-Tao Zhang, Ying Wang, Gang Wang
Introduction
In patients with pulmonary nodules (PNs), computed tomography (CT)-guided localization is commonly performed prior to the resection of these nodules through video-assisted thoracic surgery (VATS).

Aim
To evaluate the relative clinical efficacy of coil and anchored needle (AN) insertion as approaches to preoperative CT-guided PN localization.

Material and methods
This single-center, prospective, open-label, randomized controlled trial (registration number: NCT05183945) enrolled consecutive patients from January 2022 to July 2022, assigning these patients at random to undergo either coil or AN localization prior to VATS. Efficacy and safety outcomes in these two groups were then compared.

Results
This study enrolled in total 100 patients with 120 PNs who were assigned at random to the coil (patients = 50; PNs = 60) and AN (patients = 50; PNs = 60) localization groups. The respective technical success rates for coil and AN localization were 98.3% (59/60) and 100% (60/60), with no significant difference between the groups (p = 1.000). The coil group had a significantly longer median duration of localization relative to the AN group (16.0 min vs. 8.0 min, p < 0.001). Similar rates of localization-related pneumothorax (8.3% vs. 5.0%, p = 0.715) and pulmonary hemorrhage (5.0% vs. 13.3%, p = 0.110) were observed in both groups. In addition, the VATS resection procedures achieved 100% technical success rates in both of these localization groups.

Conclusions
Both coil- and AN-based localization approaches can be successfully employed to localize PNs prior to VATS resection, with the AN localization procedure requiring less time to complete on average as compared to the coil-based approach.

导言在肺结节(PNs)患者中,通常在通过视频辅助胸腔手术(VATS)切除这些结节之前进行计算机断层扫描(CT)引导下的定位。目的评估线圈和锚定针(AN)插入作为术前CT引导下PN定位方法的相对临床疗效。材料和方法这项单中心、前瞻性、开放标签、随机对照试验(注册号:NCT05183945)从 2022 年 1 月到 2022 年 7 月连续招募患者,随机分配这些患者在 VATS 术前接受线圈或 AN 定位。结果这项研究共招募了 100 名患者,120 个 PNs,随机分配到线圈(患者 = 50;PNs = 60)和 AN(患者 = 50;PNs = 60)定位组。线圈和 AN 定位的技术成功率分别为 98.3%(59/60)和 100%(60/60),组间无显著差异(P = 1.000)。线圈组的定位中位持续时间明显长于 AN 组(16.0 分钟 vs. 8.0 分钟,p < 0.001)。两组中与定位相关的气胸(8.3% vs. 5.0%,p = 0.715)和肺出血(5.0% vs. 13.3%,p = 0.110)发生率相似。结论在 VATS 切除术前,线圈定位法和 AN 定位法均可成功定位 PN,与线圈定位法相比,AN 定位法平均所需时间更短。
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Videosurgery and Other Miniinvasive Techniques
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