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Early results of laparoscopic single‑anastomosis duodeno‑ileal bypass with sleeve gastrectomy: a case series from a single Polish bariatric center. 腹腔镜十二指肠回肠单吻合术加袖式胃切除术的早期结果:来自波兰单一减肥中心的病例系列。
IF 1.6 4区 医学 Q2 SURGERY Pub Date : 2024-11-19 eCollection Date: 2024-12-27 DOI: 10.20452/wiitm.2024.17912
Mateusz Wityk, Maciej Bobowicz, Mateusz Pryt, Natalia Dowgiałło-Gornowicz

Introduction: The obesity epidemic has led to an increased prevalence of related conditions, such as type 2 diabetes (T2D) and hypertension. While laparoscopic sleeve gastrectomy is the most common metabolic bariatric surgery, up to 50% of patients may require revisional procedures due to weight regain or comorbidity recurrence. Single-anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) is emerging as an effective treatment option with promising short-term outcomes.

Aim: This study aimed to present the outcomes of patients who underwent SADI-S or revisional SADI.

Materials and methods: This retrospective, single-center cohort study included 12 patients who underwent SADI-S or SADI between February 2023 and March 2024. The patients were assessed for percentage of total weight loss (%TWL), remission of T2D and hypertension, length of hospital stay, operative time, and complications. All outcomes were reported according to the American Society for Metabolic and Bariatric Surgery standards.

Results: A total of 9 patients underwent primary SADI-S and 3 underwent revisional SADI. The mean (SD) %TWL was 27.9% (4.3%) at 6 months and 31.1% (5.9%) at 12 months after SADI and 21.2% (15.2%) and 14% (7.5%), respectively, after SADI-S. The mean (SD) preoperative body mass index was 42 (5.5) kg/m2 in the primary SADI-S group and 42.4 (9.3) kg/m2 in the revisional SADI group, and the mean (SD) follow-up was 10.1 (3.4) months. Full remission of T2D and hypertension was achieved in all patients within 6 months of surgery. There were no major complications, except for 1 case of intraoperative conversion to one-anastomosis gastric bypass.

Conclusions: SADI-S is associated with significant weight loss and comorbidity resolution with a low complication rate, though larger studies are needed for further validation of these results.

肥胖症的流行导致了相关疾病的患病率增加,如2型糖尿病(T2D)和高血压。虽然腹腔镜袖胃切除术是最常见的代谢性减肥手术,但由于体重反弹或合并症复发,高达50%的患者可能需要翻修手术。单吻合术十二指肠回肠旁路与套筒胃切除术(SADI-S)是一种有效的治疗选择,短期效果良好。目的:本研究旨在介绍SADI- s或改进型SADI患者的预后。材料和方法:这项回顾性的单中心队列研究包括12例在2023年2月至2024年3月期间接受过SADI- s或SADI的患者。评估患者的总体重减轻百分比(%TWL)、T2D和高血压缓解、住院时间、手术时间和并发症。所有结果均按照美国代谢与减肥外科学会的标准进行报告。结果:共有9例患者接受了原发性SADI- s, 3例接受了改进性SADI。SADI后6个月和12个月的平均(SD) %TWL分别为27.9%(4.3%)和31.1% (5.9%),SADI- s后分别为21.2%(15.2%)和14%(7.5%)。原发性SADI- s组术前体重指数平均(SD)为42 (5.5)kg/m2,改进型SADI组术前体重指数平均(SD)为42.4 (9.3)kg/m2,平均(SD)随访10.1(3.4)个月。所有患者在手术6个月内均实现T2D和高血压的完全缓解。除术中转单口胃旁路术1例外,无重大并发症。结论:SADI-S与显著的体重减轻和低并发症发生率相关,但需要更大规模的研究来进一步验证这些结果。
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引用次数: 0
Adoption of the Polish Bariatric and Metabolic Surgery Care Standards: a nationwide survey. 波兰减肥和代谢手术护理标准的采用:一项全国性调查。
IF 1.6 4区 医学 Q2 SURGERY Pub Date : 2024-11-15 eCollection Date: 2024-12-27 DOI: 10.20452/wiitm.2024.17911
Mateusz J Świerz, Karolina Majdak, Andrzej Budzyński, Wiesław Tarnowski, Piotr Major, Małgorzata M Bala

Introduction: Metabolic and bariatric surgery (MBS) is the most effective treatment for severe obesity, providing substantial weight loss and improvement in obesity-related comorbidities. In 2020, the MBS Chapter of the Association of Polish Surgeons issued the Bariatric and Metabolic Surgery Care Standards to guide patient management.

Aim: The aim of the study was to asses implementation of the standards in Polish surgical departments and identify factors associated with better compliance.

Materials and methods: An online survey was distributed between August and December 2022 to 46 Polish surgical departments performing MBS. The survey included 62 questions covering general center characteristics, and pre-, peri-, and postoperative care. Descriptive statistics summarized the center characteristics and linear regression models analyzed the factors influencing compliance.

Results: Thirty-six centers completed the survey, with a mean (SD) compliance score of 86.8% (9%) (29.5 of 34 criteria), and individual scores ranging from 70.6% to 100%. As many as 66.7% of the centers answered at least 80% of the questions. The areas with compliance below 80% included availability of adapted radiology facilities, constant availability of emergency radiology diagnostics, screening for metabolic markers, assessment of obstructive sleep apnea risk, obtaining patient declaration of abstaining from smoking, providing dates for at least 1 dietary consultation upon discharge, requiring at least 2 consultations with an experienced dietician, and employing a surgeon with bariatric certificate of excellence. Significant predictors of better compliance included the number of surgeons performing MBS and participation in the KOS-BAR program (a program of complex specialist care over patient undergoing bariatric surgery).

Conclusions: The Bariatric and Metabolic Surgery Care Standards are moderately well adopted by Polish surgical departments, with improvements needed in specific areas. Unifying the standards may enhance patient outcomes.

简介:代谢和减肥手术(MBS)是治疗严重肥胖最有效的方法,可显著减轻体重并改善肥胖相关的合并症。2020年,波兰外科医生协会MBS分会发布了《减肥和代谢手术护理标准》,以指导患者管理。目的:本研究的目的是评估波兰外科部门标准的实施情况,并确定与更好的依从性相关的因素。材料和方法:在2022年8月至12月期间,对波兰46个实施MBS的外科部门进行了在线调查。调查包括62个问题,包括一般中心特征、术前、围手术期和术后护理。描述性统计总结中心特征,线性回归模型分析影响依从性的因素。结果:36个中心完成了调查,平均(SD)依从性评分为86.8%(9%)(34项标准中的29.5项),个别评分范围为70.6%至100%。多达66.7%的中心回答了至少80%的问题。依从性低于80%的领域包括适应放射设备的可用性,紧急放射诊断的持续可用性,代谢标志物的筛查,阻塞性睡眠呼吸暂停风险的评估,获得患者戒烟声明,出院时提供至少1次饮食咨询的日期,要求至少2次咨询经验丰富的营养师,并雇用具有卓越减肥证书的外科医生。更好的依从性的重要预测因素包括实施MBS的外科医生数量和参与KOS-BAR计划(一个对接受减肥手术的患者进行复杂专科护理的计划)。结论:波兰外科部门对《减肥与代谢外科护理标准》的采用情况较好,但在特定领域有待改进。统一这些标准可能会提高患者的治疗效果。
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引用次数: 0
Can laparoscopic common bile duct exploration be performed without any drainage? A propensity score-matched study. 腹腔镜胆总管探查可不可以不引流?倾向评分匹配研究。
IF 1.6 4区 医学 Q2 SURGERY Pub Date : 2024-11-07 eCollection Date: 2024-12-27 DOI: 10.20452/wiitm.2024.17909
Chufa Zheng, Weifeng Wang, Qiquan Peng, Yunheng Peng, Xiaozhong Wang

Introduction: Although laparoscopic common bile duct exploration (LCBDE) is considered a safe and effective method for treating choledocholithiasis, the absence of any biliary or abdominal drainage during surgery remains controversial.

Aim: This paper aims to investigate the feasibility and safety of LCBDE without drainage, particularly abdominal drainage.

Materials and methods: This retrospective analysis included 499 patients who underwent LCBDE with primary closure of the common bile duct and without any kind of biliary drainage during surgery. In 322 individuals, the surgery involved routine abdominal drainage (drainage group), whereas in 177 cases, no abdominal drainage was performed (nondrainage group). Baseline characteristics of the 2 groups were compared, followed by propensity score matching (PSM) to balance confounding factors. We compared effect indicators and complication rates between both groups.

Results: After PSM, each group included 124 patients. There were no significant differences between the 2 groups in terms of overall and individual complication rates, except for a lower incidence of hyperamylasemia in the nondrainage group. The surgery time, duration of postoperative antibiotic use, and the total and postoperative length of hospital stay was significantly shorter in the nondrainage group. Similarly, the total hospitalization cost and postoperative usage of analgesics and antispasmodics were also considerably lower in the nondrainage group.

Conclusions: Nondrainage LCBDE is associated with shorter recovery time and better patient outcomes, as compared with procedures involving abdominal drainage. In suitable cases, this approach is completely safe and feasible.

导言:尽管腹腔镜胆总管探查术(LCBDE)被认为是治疗胆总管结石的一种安全有效的方法,但在手术过程中不进行任何胆道或腹腔引流仍存在争议。目的:本文旨在研究LCBDE不引流(尤其是腹腔引流)的可行性和安全性:这项回顾性分析纳入了 499 例接受低胆固醇胆囊切除术(LCBDE)的患者,这些患者在手术过程中进行了胆总管原发性闭合,但未进行任何形式的胆道引流。其中 322 例患者的手术涉及常规腹腔引流(引流组),177 例患者未进行腹腔引流(非引流组)。我们比较了两组患者的基线特征,然后进行倾向评分匹配(PSM)以平衡混杂因素。我们比较了两组的效果指标和并发症发生率:结果:经过倾向评分匹配后,两组各包括 124 名患者。除了不引流组的高淀粉血症发生率较低外,两组在总体和单个并发症发生率方面没有明显差异。无引流组的手术时间、术后使用抗生素的时间以及总住院时间和术后住院时间明显较短。同样,无引流组的住院总费用以及术后镇痛药和解痉药的使用量也大大降低:结论:与腹腔引流手术相比,无引流低密度腹腔结肠切除术的恢复时间更短,患者的预后更好。在合适的病例中,这种方法完全安全可行。
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引用次数: 0
Intervention effect of ventilator‑assisted emergency endoscopy in the treatment of cirrhosis‑associated esophagogastric variceal bleeding. 呼吸机辅助急诊内镜治疗肝硬化相关食管胃静脉曲张出血的干预效果。
IF 1.6 4区 医学 Q2 SURGERY Pub Date : 2024-11-07 eCollection Date: 2024-12-27 DOI: 10.20452/wiitm.2024.17908
Xiu-Lian Wu, Yanmei Gu, Wenhui Wang, Jiayuan Wei, Xiaoqing Sun, Wenyue Hu, Wenhui He

Introduction: Emergency endoscopy has proven remarkably effective in the treatment of gastrotestinal bleeding. However, its efficacy has not been extensively evaluated specifically in patients with cirrhosis‑associated esophagogastric variceal bleeding (EGVB). The patients may experience stress and anxiety before being subjected to the procedure.

Aim: This study aimed to investigate the effect of ventilator‑assisted emergency endoscopy in the treatment of cirrhosis‑associated EGVB.

Materials and methods: A total of 63 patients with cirrhosis‑associated EGVB were enrolled in the study and divided into 2 groups using the random number table method. The control group (n = 31) received conventional emergency endoscopic hemostasis, while the observational group (n = 32) underwent ventilator‑assisted emergency endoscopic hemostasis. The hemostatic success rate, post‑treatment rebleeding rate, postoperative complication rate, length of stay in the intensive care unit (ICU), cost of hospitalization, and the patients' feeling of comfort (eg, fever and anxiety) were assessed in both groups.

Results: There were no significant differences in the hemostatic success rate, rebleeding rate, mortality, length of stay in the ICU, or cost of hospitalization between the groups. The symptoms and feelings of anxiety and pain in the observational group were significantly less intense than in the control group. However, there was no significant difference in the frequency of postoperative fever between the groups.

Conclusions: In the emergency endoscopic treatment of patients with cirrhosis‑associated EGVB, using a ventilator ensures a smooth airway, keeps patients sedated throughout the procedure, and enhances their overall comfort. Ventilator‑assisted emergency endoscopy helps alleviate postoperative pain and reduces anxiety.

简介:事实证明,急诊内镜检查在治疗胃肠道出血方面效果显著。然而,专门针对肝硬化相关食管胃底静脉曲张出血(EGVB)患者的疗效尚未得到广泛评估。目的:本研究旨在探讨呼吸机辅助急诊内镜在治疗肝硬化相关性食管胃底静脉曲张出血中的效果:研究共纳入 63 例肝硬化相关 EGVB 患者,采用随机数字表法将其分为两组。对照组(31 人)接受常规急诊内镜止血,观察组(32 人)接受呼吸机辅助急诊内镜止血。对两组患者的止血成功率、治疗后再出血率、术后并发症发生率、重症监护室(ICU)住院时间、住院费用以及患者的舒适感(如发热和焦虑)进行了评估:结果:两组患者的止血成功率、再出血率、死亡率、重症监护室住院时间和住院费用均无明显差异。观察组的焦虑和疼痛症状和感觉明显少于对照组。然而,两组患者术后发烧的频率没有明显差异:结论:在对肝硬化相关 EGVB 患者进行急诊内镜治疗时,使用呼吸机可确保气道通畅,使患者在整个手术过程中保持镇静,并提高患者的整体舒适度。呼吸机辅助急诊内镜检查有助于减轻术后疼痛和焦虑。
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引用次数: 0
Preoperative computed tomography-guided localization of pulmonary ground‑glass nodules: a comparison of conventional and soft hook‑wires. 术前计算机断层扫描引导肺磨玻璃结节定位:常规与软钩线的比较。
IF 1.6 4区 医学 Q2 SURGERY Pub Date : 2024-11-07 eCollection Date: 2024-12-27 DOI: 10.20452/wiitm.2024.17910
Sheng-Zhi Fan, Yu-Yu Ma, Yan Sun, Hao Xu, Wei Chen

Introduction: Hook-wire (HW) localization is the most frequently employed approach for preoperative localization of pulmonary ground-glass nodules (GGNs); however, the relative outcomes of conventional and soft HW localization of GGNs remain poorly understood.

Aim: This study sought to compare the safety and efficacy of preoperative computed tomography-guided conventional and soft HW localization of pulmonary GGNs.

Materials and methods: Between January 2023 and June 2024, consecutive patients with pulmonary GGNs underwent conventional or soft HW localization prior to video-assisted thoracoscopic surgery. Safety and clinical efficacy of these 2 localization strategies were compared.

Results: In total, 88 patients underwent conventional HW localization of 95 GGNs, and 82 patients underwent soft HW localization of 88 GGNs. Technical success rates for the conventional and soft HW groups were 96.8% and 100%, respectively (P = 0.25), and the duration of localization was similar in both groups (mean [SD], 10.1 [4.5] vs 10 [5.9] min; P = 0.97). Complications were significantly more common in the conventional HW group than in the soft HW group (48.9% vs 32.9%, respectively; P = 0.04). Visual analog scale scores in the conventional HW group were significantly higher than those observed in the soft HW group (mean [SD], 4.6 [0.6] vs 3.4 [0.6]; P = 0.001). The rates of technical success for limited resection procedures were similar in both groups (96.8% vs 100% in the conventional and soft HW groups, respectively; P >0.99).

Conclusions: Conventional and soft HW strategies can both effectively facilitate preoperative pulmonary GGN localization, but the soft HW approach has a more favorable safety profile.

导言:钩丝定位(Hook-wire, HW)是肺磨玻璃结节(GGNs)术前最常用的定位方法;然而,ggn的常规定位和软HW定位的相对结果仍然知之甚少。目的:本研究旨在比较术前ct引导下常规定位和软HW定位肺部ggn的安全性和有效性。材料和方法:在2023年1月至2024年6月期间,连续的肺部ggn患者在电视胸腔镜手术前接受常规或软HW定位。比较两种定位策略的安全性和临床疗效。结果:88例患者95个ggn行常规HW定位,82例患者88个ggn行软HW定位。常规组和软HW组的技术成功率分别为96.8%和100% (P = 0.25),两组定位时间相似(平均[SD], 10.1 [4.5] vs 10 [5.9] min;P = 0.97)。常规HW组并发症发生率明显高于软HW组(分别为48.9% vs 32.9%;P = 0.04)。常规HW组视觉模拟量表评分显著高于软HW组(mean [SD], 4.6 [0.6] vs . 3.4 [0.6];P = 0.001)。两组有限切除手术的技术成功率相似(常规组和软HW组分别为96.8%和100%;P > 0.99)。结论:常规和软HW策略均能有效促进术前肺部GGN定位,但软HW方法安全性更佳。
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引用次数: 0
Learning curve and complications of unilateral biportal endoscopy-unilateral laminectomy bilateral decompression for lumbar spinal stenosis. 单侧双门静脉内窥镜-单侧椎板切除术治疗腰椎管狭窄的学习曲线及并发症。
IF 1.6 4区 医学 Q2 SURGERY Pub Date : 2024-11-05 eCollection Date: 2024-12-27 DOI: 10.20452/wiitm.2024.17905
Jiashen Shao, Zihan Fan, Hai Meng, Qi Fei

Introduction: The unilateral biportal endoscopic (UBE) technique has been widely adopted for treat‑ ment of lumbar disc herniation and lumbar spinal stenosis. Understanding its learning curve, as well as the factors that influence perioperative complications, is crucial for mastering and effectively learning this technique.

Aim: Our aim was to analyze the learning curve of UBE‑unilateral laminectomy bilateral decompression (ULBD) and risk factors associated with perioperative complications.

Materials and methods: Consecutive patients who underwent UBE from June 2021 to December 2023 at the Department of Orthopedics, Beijing Friendship Hospital, were retrospectively analyzed. Baseline information, perioperative data, and preoperative and postoperative subjective scores were recorded for all patients. The learning curve and identified risk factors for complications were analyzed.

Results: A total of 122 consecutive patients who underwent single‑segment UBE‑ULBD were included in this study. The surgical time curve fitting indicated that the surgeon nearly mastered the technique by the 38th case. Consequently, the cohort was divided into 2 distinct phases: a learning phase (cases 1-38) and a mastery phase (cases 39-122). Operative time, estimated blood loss, and drainage volume were higher in the learning phase group than in the mastery phase group, although hidden blood loss in the learning phase group was lower than in the mastery phase group. The visual analogue scale and Oswestry Disability Index scores at the last follow‑up showed significant improvement in both groups as compared with the preoperative period (P <0.05). Complication rate was 7.9% in the learning phase and 3.6% in the mastery phase. Univariate analysis showed that age, body mass index, alcohol consumption, and estimated blood loss were significantly associated with complication rate.

Conclusions: UBE is an effective minimally‑invasive spinal endoscopic technique for treating lumbar spinal stenosis, offering short time to achieving surgical mastery and a low complication rate.

单侧双门静脉内镜(UBE)技术已被广泛应用于腰椎间盘突出症和腰椎管狭窄症的治疗。了解其学习曲线,以及影响围手术期并发症的因素,对于掌握和有效学习这项技术至关重要。目的:我们的目的是分析UBE -单侧椎板切除术双侧减压(ULBD)的学习曲线和围手术期并发症的相关危险因素。材料和方法:回顾性分析北京友谊医院骨科2021年6月至2023年12月连续行UBE手术的患者。记录所有患者的基线信息、围手术期数据以及术前和术后主观评分。分析学习曲线和确定的并发症危险因素。结果:本研究共纳入了122例连续接受单节段UBE - ULBD的患者。手术时间曲线拟合表明,到第38例时,术者已基本掌握手术技术。因此,该队列被分为两个不同的阶段:学习阶段(病例1-38)和掌握阶段(病例39-122)。学习期组的隐性失血量低于掌握期组,但学习期组的手术时间、估计失血量和引流量均高于掌握期组。最后一次随访时,两组患者的视觉模拟评分和Oswestry残疾指数评分均较术前有显著改善(P)。结论:UBE是治疗腰椎管狭窄症的一种有效的微创脊柱内窥镜技术,掌握手术时间短,并发症发生率低。
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引用次数: 0
Conventional and drug‑eluting bead transarterial chemoembolization in patients with inoperable intrahepatic cholangiocarcinoma: a meta‑analysis. 常规和药物洗脱经动脉化疗栓塞治疗不能手术的肝内胆管癌患者:荟萃分析
IF 1.6 4区 医学 Q2 SURGERY Pub Date : 2024-11-05 eCollection Date: 2024-12-27 DOI: 10.20452/wiitm.2024.17906
Su-Rong Pan, Xue-Wen Wo, Hong-Fang Zhu, Feng-Fei Xia

Introduction: In patients with inoperable intrahepatic cholangiocarcinoma (ICC), both conventional transarterial chemoembolization (cTACE) and drug‑eluting bead TACE (DEB‑TACE) can be employed as therapeutic interventions. However, the relative advantages of these strategies remain to be clarified.

Aim: This meta‑analysis was performed to compare the safety and efficacy of DEB‑TACE and cTACE in the treatment of ICC.

Materials and methods: A comprehensive search of the Cochrane Library, PubMed, and Wanfang databases was conducted to identify publications that were pertinent to the present meta‑analysis. The primary outcome of interest was the overall survival (OS) rate. Secondary outcomes were progression‑free survival (PFS), disease control rate (DCR), objective response rate (ORR), and adverse event (AE) rate. Heterogeneity was evaluated using the I 2 statistic, while publication bias was assessed with the Egger test.

Results: A total of 6 articles involving 283 and 178 patients who received cTACE and DEB‑TACE treatment, respectively, were included in this study. DEB‑TACE was superior to cTACE in terms of DCR (P = 0.004), PFS (P <0.001), and OS (P = 0.004), despite comparable pooled ORRs. No intergroup differences were observed with respect to AE occurrence. The ORR, DCR, and OS end points showed significant heterogeneity (I2 = 79%, I2 = 61%, and I2 = 95%, respectively). Additionally, the OS end point was subject to substantial publication bias (Egger test, P = 0.002).

Conclusions: DEB‑TACE was shown to be superior to cTACE with respect to efficacy, while the safety profile of these 2 interventions was similar. Consequently, DEB‑TACE offers additional value in the management of inoperable ICC.

简介:对于无法手术的肝内胆管癌(ICC)患者,传统的经动脉化疗栓塞术(cTACE)和药物洗脱珠TACE(DEB-TACE)均可作为治疗手段。目的:本荟萃分析旨在比较 DEB-TACE 和 cTACE 治疗 ICC 的安全性和有效性:对Cochrane图书馆、PubMed和万方数据库进行了全面检索,以确定与本荟萃分析相关的出版物。主要研究结果为总生存率(OS)。次要结果为无进展生存期(PFS)、疾病控制率(DCR)、客观反应率(ORR)和不良事件率(AE)。异质性采用I 2统计量进行评估,发表偏倚采用Egger检验进行评估:本研究共纳入了 6 篇文章,分别涉及 283 名和 178 名接受 cTACE 和 DEB-TACE 治疗的患者。DEB-TACE在DCR(P = 0.004)和PFS(P P = 0.004)方面优于cTACE,尽管两者的总ORR相当。在AE发生率方面未观察到组间差异。ORR、DCR和OS终点显示出显著的异质性(分别为I2 = 79%、I2 = 61%和I2 = 95%)。此外,OS终点也存在很大的发表偏倚(Egger检验,P = 0.002):结论:DEB-TACE的疗效优于cTACE,而这两种干预方法的安全性相似。因此,DEB-TACE 为无法手术的 ICC 的治疗提供了更多价值。
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引用次数: 0
Percutaneous cryoablation of kidney tumors after partial nephrectomy. 肾部分切除术后经皮肾肿瘤冷冻消融。
IF 1.6 4区 医学 Q2 SURGERY Pub Date : 2024-10-25 eCollection Date: 2024-12-27 DOI: 10.20452/wiitm.2024.17904
Wojciech Krajewski, Maciej Guziński, Wojciech Tomczak, Łukasz Nowak, Jan Łaszkiewicz, Joanna Chorbińska, Adam Chełmoński, Katarzyna Grunwald, Bartosz Małkiewicz, Tomasz Szydełko

Introduction: The widespread use of ultrasound and cross‑sectional imaging has led to a steady increase in the incidental discovery of renal masses. Most of them are treated with partial nephrectomy (PN), as recommended by the European Association of Urology guidelines. However, this approach carries a risk of local recurrence. In such a case, surgical reintervention can be more challenging and is often associated with worse prognosis. In this context, percutaneous ablative therapies are a promising alternative.

Aim: This study presents our experience with using percutaneous cryoablation (PCA) to manage recurrences and new masses in previously operated kidneys.

Materials and methods: We conducted a retrospective data analysis to evaluate patients treated with PCA for tumor recurrence or residual disease in the postresection bed, excluding those with de novo or recurrent tumors in the contralateral kidney.

Results: A total of 23 individuals met the inclusion criteria. Of those, 14 initially underwent laparoscopic PN, and 9 were treated with open surgery. The median interval from the initial surgery to recurrence‑targeted PCA was 23 months (range, 7-228). The mean (SD) RENAL score on admission was 7.5 (1.9), and the median (interquartile range) tumor volume was 3 (1.6-4.5) ml. The median length of hospital stay was 23 hours (range, 6-55). There was no significant change in estimated glomerular filtration rate following cryoablation. All the recorded complications, except one, were grade I and resolved with hydration or treatment with nonsteroidal anti‑inflammatory drugs. No patient required dialysis in the perioperative period.

Conclusions: Imaging‑guided PCA is a feasible and effective treatment option for patients with renal tumor recurrences after PN.

导语:超声和横断面成像的广泛应用导致偶然发现的肾脏肿块稳步增加。根据欧洲泌尿外科协会指南的建议,大多数患者采用部分肾切除术(PN)治疗。然而,这种方法有局部复发的风险。在这种情况下,手术再干预可能更具挑战性,通常伴有较差的预后。在这种情况下,经皮消融治疗是一个很有前途的选择。目的:本研究介绍了我们使用经皮冷冻消融(PCA)来处理以前手术过的肾脏复发和新肿块的经验。材料和方法:我们对采用PCA治疗的患者进行回顾性资料分析,以评估术后肿瘤复发或残留病变,不包括对侧肾脏新生或复发肿瘤。结果:共有23人符合纳入标准。其中,14人最初接受了腹腔镜PN, 9人接受了开放手术。从首次手术到针对复发的PCA的中位时间间隔为23个月(范围7-228)。入院时肾脏评分的平均值(SD)为7.5(1.9),肿瘤体积的中位数(四分位数范围)为3 (1.6-4.5)ml。住院时间的中位数为23小时(范围6-55)。冷冻消融后估计肾小球滤过率无显著变化。除一例外,所有记录的并发症均为I级,并通过水合或非甾体类抗炎药治疗得到解决。围手术期无患者需要透析。结论:影像引导下的PCA对于肾肿瘤PN术后复发患者是一种可行且有效的治疗选择。
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引用次数: 0
Clinical efficacy of various resuscitation fluids in the management of sepsis in postoperative surgical and trauma patients: a systematic review and meta--analysis. 各种复苏液体在外科和创伤术后脓毒症治疗中的临床疗效:系统回顾和荟萃分析
IF 1.6 4区 医学 Q2 SURGERY Pub Date : 2024-09-20 eCollection Date: 2024-10-16 DOI: 10.20452/wiitm.2024.17900
Yongjie Wang, Kewu Chen, Xiaolu Li, Jianing Guan

Introduction: Fluid resuscitation is the primary sepsis management strategy aimed at reducing mortality and achieving better treatment outcomes in critically hypotensive patients. Still, there are significant ambiguities regarding the most suitable fluid type that would ensure optimization of patient outcomes.

Aim: The aim of this systematic review and meta-analysis was to assess the clinical effectiveness of different resuscitation fluids for sepsis management in critically hypotensive patients.

Materials and methods: A systematic search of 4 electronic databases (PubMed, EMBASE, Scopus, and Cochrane Library) was conducted to identify relevant papers published in peer-reviewed journals since database inception until June 30, 2024. Odds ratios (ORs) with 95% CIs were calculated to evaluate the impact of individual resuscitation fluids on improvements in hemodynamic parameters and all-cause mortality. Heterogeneity was assessed using the Cochran Q, I2 statistic, and the appropriate P value.

Results: Our meta-analysis included 18 randomized controlled trials comparing the efficacy of different resuscitation fluids for sepsis management in 14 469 critically hypotensive patients. We found that Ringer's lactate solution was more effective than saline in reducing mortality (OR, 0.53; 95% CI, 0.41-0.7; χ2= 3.47; degree of freedom [df] = 6; Z = 4.6; I2 = 0%; P <⁠0.001) and improving hemodynamic parameters (OR, 2.64; 95% CI, 2.45-2.86; χ2 = 48.36; df = 6; Z = 24.84; I2 = 18%; P <⁠0.001). However, saline was superior to albumin and hydroxyethyl starch in reaching these end points.

Conclusion: We showed that in critically hypotensive septic patients, Ringer's lactate solution reduces all-cause mortality and improves hemodynamic parameters more effectively than saline, hydroxyethyl starch, and albumin solutions.

简介:液体复苏是主要的脓毒症管理策略,旨在降低死亡率,并取得较好的治疗效果的严重低血压患者。尽管如此,对于确保患者预后最佳的最合适的液体类型,仍存在显著的模糊性。目的:本系统综述和荟萃分析的目的是评估不同复苏液体对严重低血压患者脓毒症管理的临床效果。材料与方法:系统检索PubMed、EMBASE、Scopus、Cochrane Library 4个电子数据库,检索自数据库建立至2024年6月30日在同行评议期刊上发表的相关论文。计算95% ci的优势比(or),以评估个别复苏液体对改善血流动力学参数和全因死亡率的影响。采用Cochran Q、I2统计量和相应的P值评估异质性。结果:我们的荟萃分析包括18项随机对照试验,比较了14469例危重低血压患者不同复苏液体对脓毒症管理的疗效。我们发现乳酸林格液在降低死亡率方面比生理盐水更有效(OR, 0.53;95% ci, 0.41-0.7;χ2 = 3.47;自由度[df] = 6;Z = 4.6;I2 = 0%;P 2 = 48.36;Df = 6;Z = 24.84;I2 = 18%;结论:我们发现,在严重低血压脓毒症患者中,乳酸林格液比生理盐水、羟乙基淀粉和白蛋白溶液更有效地降低了全因死亡率,改善了血液动力学参数。
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引用次数: 0
Outcomes of laparoscopic transabdominal preperitoneal hernia repair in the elderly population: a retrospective cohort study. 老年人腹腔镜经腹腹膜前疝修补术的结果:一项回顾性队列研究。
IF 1.6 4区 医学 Q2 SURGERY Pub Date : 2024-09-20 eCollection Date: 2024-10-16 DOI: 10.20452/wiitm.2024.17899
Dawid Golik, Krzysztof Jędras, Przemysław Sroczyński, Grzegorz Dobkowski, Michał R Janik

Introduction: Hernia repair is a common procedure, especially among the elderly. In the face of rising life expectancy, adequate hernia management in older adults is crucial. Laparoscopic transabdominal preperitoneal patch plasty (TAPP) for hernia repair is minimally invasive, but poses challenges in the elderly due to a larger number of comorbidities.

Aim: The aim of this study was to evaluate the safety and efficacy of TAPP hernia repair in patients aged 70 years and older.

Materials and methods: Our retrospective study reviewed data of patients who underwent elective unilateral TAPP repair for primary inguinal hernia between September 2021 and December 2023. The patients were divided by age: 70 and older (cases) and younger than 70 (controls). Primary outcomes included recurrence rate, surgical site infections (SSIs), operative time, and hospital stay. Data were analyzed with descriptive statistics and inferential tests.

Results: The study included 201 patients (47 cases and 154 controls). The mean (SD) age was 75.74 (4.73) years for the cases and 53.47 (12.8) years for the controls. No recurrences were found in the elderly (cases) group, while the control group recorded a 3.92% recurrence rate (P = 0.34). SSIs affected 2.13% of the cases and 1.31% of the controls (P = 0.55). Operative times were similar (71.44 vs 71.96 min; P = 0.8). Hospital stay was 3.11 days for the cases and 3.04 days for the controls (P = 0.14).

Conclusions: Laparoscopic TAPP hernia repair is a safe and effective procedure in the elderly and its outcomes are comparable to those recorded in younger patients. Further studies are needed to validate these results.

简介疝气修补术是一种常见的手术,尤其是在老年人中。随着预期寿命的延长,对老年人进行适当的疝气治疗至关重要。腹腔镜经腹腹膜前补片成形术(TAPP)用于疝修补术是一种微创手术,但由于老年人合并症较多,因此对他们来说是一项挑战。目的:本研究旨在评估 70 岁及以上患者接受 TAPP 疝修补术的安全性和有效性:我们的回顾性研究回顾了 2021 年 9 月至 2023 年 12 月期间接受选择性单侧 TAPP 修补术治疗原发性腹股沟疝的患者数据。患者按年龄分为:70 岁及以上(病例)和 70 岁以下(对照)。主要结果包括复发率、手术部位感染(SSI)、手术时间和住院时间。数据采用描述性统计和推理检验进行分析:研究共纳入 201 名患者(47 例病例和 154 例对照)。病例的平均(标清)年龄为 75.74(4.73)岁,对照组为 53.47(12.8)岁。老年组(病例)未发现复发,而对照组的复发率为 3.92%(P = 0.34)。2.13%的病例和1.31%的对照组发生了SSI(P = 0.55)。手术时间相似(71.44 分钟 vs 71.96 分钟;P = 0.8)。病例的住院时间为3.11天,对照组为3.04天(P = 0.14):结论:腹腔镜TAPP疝修补术对老年人来说是一种安全有效的手术,其疗效与年轻患者相当。需要进一步研究来验证这些结果。
{"title":"Outcomes of laparoscopic transabdominal preperitoneal hernia repair in the elderly population: a retrospective cohort study.","authors":"Dawid Golik, Krzysztof Jędras, Przemysław Sroczyński, Grzegorz Dobkowski, Michał R Janik","doi":"10.20452/wiitm.2024.17899","DOIUrl":"10.20452/wiitm.2024.17899","url":null,"abstract":"<p><strong>Introduction: </strong>Hernia repair is a common procedure, especially among the elderly. In the face of rising life expectancy, adequate hernia management in older adults is crucial. Laparoscopic transabdominal preperitoneal patch plasty (TAPP) for hernia repair is minimally invasive, but poses challenges in the elderly due to a larger number of comorbidities.</p><p><strong>Aim: </strong>The aim of this study was to evaluate the safety and efficacy of TAPP hernia repair in patients aged 70 years and older.</p><p><strong>Materials and methods: </strong>Our retrospective study reviewed data of patients who underwent elective unilateral TAPP repair for primary inguinal hernia between September 2021 and December 2023. The patients were divided by age: 70 and older (cases) and younger than 70 (controls). Primary outcomes included recurrence rate, surgical site infections (SSIs), operative time, and hospital stay. Data were analyzed with descriptive statistics and inferential tests.</p><p><strong>Results: </strong>The study included 201 patients (47 cases and 154 controls). The mean (SD) age was 75.74 (4.73) years for the cases and 53.47 (12.8) years for the controls. No recurrences were found in the elderly (cases) group, while the control group recorded a 3.92% recurrence rate (<i>P</i> = 0.34). SSIs affected 2.13% of the cases and 1.31% of the controls (<i>P</i> = 0.55). Operative times were similar (71.44 vs 71.96 min; <i>P</i> = 0.8)<i>.</i> Hospital stay was 3.11 days for the cases and 3.04 days for the controls (<i>P</i> = 0.14).</p><p><strong>Conclusions: </strong>Laparoscopic TAPP hernia repair is a safe and effective procedure in the elderly and its outcomes are comparable to those recorded in younger patients. Further studies are needed to validate these results.</p>","PeriodicalId":49361,"journal":{"name":"Videosurgery and Other Miniinvasive Techniques","volume":"19 3","pages":"325-329"},"PeriodicalIF":1.6,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11927547/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Videosurgery and Other Miniinvasive Techniques
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