Pub Date : 2022-06-01Epub Date: 2022-05-04DOI: 10.1097/JSA.0000000000000340
Filippo Migliorini, Andrea Pintore, Ernesto Torsiello, Francesco Oliva, Filippo Spiezia, Nicola Maffulli
Purpose: The present study investigated the type of sport and activity level of athletes before they underwent knee and/or hip arthroplasty for osteoarthritis (OA), and compared them with a control group of subjects who did not undergo knee and hip arthroplasty. We hypothesed athletes exposed to high physical loads during sports had the highest risk of developing OA requiring arthroplasty.
Materials and methods: This systematic review was conducted according to the PRISMA guidelines. All the comparative clinical trials to August 2021 investigating the sport activity level between subjects who underwent arthroplasty versus those who did not undergo arthroplasty for OA were considered.
Results: Data from 5 studies and 3638 patients were collected. The mean age for both groups was 47.61±15.5 years, and the mean body mass index was 24.6±2.1 kg/m2 17.6% were women. The Newcastle-Ottawa scale attested good quality of the methodology of the investigations included in the present study.
Conclusion: Intense physical exercise, implying a high cumulative number of hours of exercise which can lead to excessive joint overload, in both sexes is associated with greater likelihood of early knee and hip OA which may lead to prosthetic surgery. Moderate and recreational exposure to sport has minor degenerative effects, and is not associated with early onset OA requiring arthroplasty.
{"title":"Intensive Physical Activity Increases the Risk of Knee and Hip Arthroplasty: A Systematic Review.","authors":"Filippo Migliorini, Andrea Pintore, Ernesto Torsiello, Francesco Oliva, Filippo Spiezia, Nicola Maffulli","doi":"10.1097/JSA.0000000000000340","DOIUrl":"https://doi.org/10.1097/JSA.0000000000000340","url":null,"abstract":"<p><strong>Purpose: </strong>The present study investigated the type of sport and activity level of athletes before they underwent knee and/or hip arthroplasty for osteoarthritis (OA), and compared them with a control group of subjects who did not undergo knee and hip arthroplasty. We hypothesed athletes exposed to high physical loads during sports had the highest risk of developing OA requiring arthroplasty.</p><p><strong>Materials and methods: </strong>This systematic review was conducted according to the PRISMA guidelines. All the comparative clinical trials to August 2021 investigating the sport activity level between subjects who underwent arthroplasty versus those who did not undergo arthroplasty for OA were considered.</p><p><strong>Results: </strong>Data from 5 studies and 3638 patients were collected. The mean age for both groups was 47.61±15.5 years, and the mean body mass index was 24.6±2.1 kg/m2 17.6% were women. The Newcastle-Ottawa scale attested good quality of the methodology of the investigations included in the present study.</p><p><strong>Conclusion: </strong>Intense physical exercise, implying a high cumulative number of hours of exercise which can lead to excessive joint overload, in both sexes is associated with greater likelihood of early knee and hip OA which may lead to prosthetic surgery. Moderate and recreational exposure to sport has minor degenerative effects, and is not associated with early onset OA requiring arthroplasty.</p>","PeriodicalId":49481,"journal":{"name":"Sports Medicine and Arthroscopy Review","volume":"30 2","pages":"111-116"},"PeriodicalIF":1.9,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41160658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-01Epub Date: 2022-05-04DOI: 10.1097/JSA.0000000000000346
Filippo Migliorini, Ernesto Torsiello, Gerardo La Padula, Francesco Oliva, Nicola Maffulli
Purpose: Intense sporting activity and certain types of work increase the risk of early osteoarthritis (OA). OA can be idiopathic or associated to certain predisposing factors: female sex, obesity, history of joint injury, and joint overuse. The role of gender among the active population as a predisposing factor for OA is not well clear. This study investigated whether the risk of OA changes with age in both sexes in physically active individuals.
Materials and methods: This systematic review was conducted according to the PRISMA guidelines 2020. PubMed, Google Scholar, Embase, and Web of Science databases were accessed in April 2021. No time constrains were used for the search. All the published clinical studies reporting data about relationship between physical activity and OA were included.
Results: Data from 7 articles were retrieved including 360,053 patients (271,903 males; 88,150 females). The mean age was 48.2±16.7 years. Males, under the age of 60 had a higher risk of developing OA. People undertaking intense physical activity, such as professional athletes or heavy workers, are more prone to develop early OA.
Conclusion: Physically active males demonstrated a higher risk of developing OA.
目的:剧烈的体育活动和某些类型的工作会增加早期骨关节炎(OA)的风险。OA可能是特发性的,也可能与某些易感因素有关:女性、肥胖、关节损伤史和关节过度使用。在活跃人群中,性别作为OA易感因素的作用尚不清楚。这项研究调查了在体力活动的个体中,OA的风险是否随年龄而变化。材料和方法:这项系统审查是根据2020年PRISMA指南进行的。PubMed、Google Scholar、Embase和Web of Science数据库于2021年4月访问。搜索没有使用时间限制。所有已发表的报告体力活动和OA之间关系的临床研究数据都包括在内。结果:检索到7篇文章的数据,包括360053名患者(271903名男性;88150名女性)。平均年龄48.2±16.7岁。60岁以下的男性患OA的风险更高。从事高强度体育活动的人,如职业运动员或重型工人,更容易患早期OA。结论:体育活动的男性患OA的风险更高。
{"title":"The Association Between Sex and Osteoarthritis in the Physically Active Population: A Systematic Review.","authors":"Filippo Migliorini, Ernesto Torsiello, Gerardo La Padula, Francesco Oliva, Nicola Maffulli","doi":"10.1097/JSA.0000000000000346","DOIUrl":"https://doi.org/10.1097/JSA.0000000000000346","url":null,"abstract":"<p><strong>Purpose: </strong>Intense sporting activity and certain types of work increase the risk of early osteoarthritis (OA). OA can be idiopathic or associated to certain predisposing factors: female sex, obesity, history of joint injury, and joint overuse. The role of gender among the active population as a predisposing factor for OA is not well clear. This study investigated whether the risk of OA changes with age in both sexes in physically active individuals.</p><p><strong>Materials and methods: </strong>This systematic review was conducted according to the PRISMA guidelines 2020. PubMed, Google Scholar, Embase, and Web of Science databases were accessed in April 2021. No time constrains were used for the search. All the published clinical studies reporting data about relationship between physical activity and OA were included.</p><p><strong>Results: </strong>Data from 7 articles were retrieved including 360,053 patients (271,903 males; 88,150 females). The mean age was 48.2±16.7 years. Males, under the age of 60 had a higher risk of developing OA. People undertaking intense physical activity, such as professional athletes or heavy workers, are more prone to develop early OA.</p><p><strong>Conclusion: </strong>Physically active males demonstrated a higher risk of developing OA.</p>","PeriodicalId":49481,"journal":{"name":"Sports Medicine and Arthroscopy Review","volume":"30 2","pages":"87-91"},"PeriodicalIF":1.9,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41174030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-04DOI: 10.1097/JSA.0000000000000348
N. Maffulli
{"title":"Osteoarthritis and the Middle Aged Athlete: The Present and Future.","authors":"N. Maffulli","doi":"10.1097/JSA.0000000000000348","DOIUrl":"https://doi.org/10.1097/JSA.0000000000000348","url":null,"abstract":"","PeriodicalId":49481,"journal":{"name":"Sports Medicine and Arthroscopy Review","volume":"30 2 1","pages":"77"},"PeriodicalIF":1.9,"publicationDate":"2022-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48664943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-04DOI: 10.1097/JSA.0000000000000337
Ryan C. Rauck, Claire D. Eliasberg, S. Rodeo, S. Rodeo
This article is dedicated to the use of orthobiologic therapies in the management of early osteoarthritis in middle-aged athletes. Understanding a patient's presenting symptoms, physical examination, imaging results, and goals is of critical importance in applying orthobiologic therapies. The field of orthobiologics is expanding at a rapid pace, and the clinical studies examining the utility of each treatment lag behind the direct-to-consumer marketing that leads to these products being used. Here we provide a review of the available treatments, emerging treatments, and the current literature supporting or refuting their use. Currently studied orthobiologics include autologous and allogenic cell therapies, autologous blood products, hyaluronic acid, gene therapies, Wnt inhibitors, and a variety of systemic treatments.
{"title":"Orthobiologics for the Management of Early Arthritis in the Middle-Aged Athlete.","authors":"Ryan C. Rauck, Claire D. Eliasberg, S. Rodeo, S. Rodeo","doi":"10.1097/JSA.0000000000000337","DOIUrl":"https://doi.org/10.1097/JSA.0000000000000337","url":null,"abstract":"This article is dedicated to the use of orthobiologic therapies in the management of early osteoarthritis in middle-aged athletes. Understanding a patient's presenting symptoms, physical examination, imaging results, and goals is of critical importance in applying orthobiologic therapies. The field of orthobiologics is expanding at a rapid pace, and the clinical studies examining the utility of each treatment lag behind the direct-to-consumer marketing that leads to these products being used. Here we provide a review of the available treatments, emerging treatments, and the current literature supporting or refuting their use. Currently studied orthobiologics include autologous and allogenic cell therapies, autologous blood products, hyaluronic acid, gene therapies, Wnt inhibitors, and a variety of systemic treatments.","PeriodicalId":49481,"journal":{"name":"Sports Medicine and Arthroscopy Review","volume":"30 2 1","pages":"e9-e16"},"PeriodicalIF":1.9,"publicationDate":"2022-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41855150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-01DOI: 10.1097/JSA.0000000000000324
Dustin R Lee, Erik Therrien, Bryant M Song, Christopher L Camp, Aaron J Krych, Michael J Stuart, Matthew P Abdel, Bruce A Levy
Arthrofibrosis (AF) is an exaggerated immune response to a proinflammatory insult leading to pathologic periarticular fibrosis and symptomatic joint stiffness. The knee, elbow, and shoulder are particularly susceptible to AF, often in the setting of trauma, surgery, or adhesive capsulitis. Prevention through early physiotherapeutic interventions and anti-inflammatory medications remain fundamental to avoiding motion loss. Reliable nonoperative modalities exist and outcomes are improved when etiology, joint involved, and level of dysfunction are considered in the clinical decision making process. Surgical procedures should be reserved for cases recalcitrant to nonoperative measures. The purpose of this review is to provide an overview of the current understanding of AF pathophysiology, identify common risk factors, describe prevention strategies, and outline both nonoperative and surgical treatment options. This manuscript will focus specifically on sterile AF of the knee, elbow, and shoulder.
{"title":"Arthrofibrosis Nightmares: Prevention and Management Strategies.","authors":"Dustin R Lee, Erik Therrien, Bryant M Song, Christopher L Camp, Aaron J Krych, Michael J Stuart, Matthew P Abdel, Bruce A Levy","doi":"10.1097/JSA.0000000000000324","DOIUrl":"10.1097/JSA.0000000000000324","url":null,"abstract":"<p><p>Arthrofibrosis (AF) is an exaggerated immune response to a proinflammatory insult leading to pathologic periarticular fibrosis and symptomatic joint stiffness. The knee, elbow, and shoulder are particularly susceptible to AF, often in the setting of trauma, surgery, or adhesive capsulitis. Prevention through early physiotherapeutic interventions and anti-inflammatory medications remain fundamental to avoiding motion loss. Reliable nonoperative modalities exist and outcomes are improved when etiology, joint involved, and level of dysfunction are considered in the clinical decision making process. Surgical procedures should be reserved for cases recalcitrant to nonoperative measures. The purpose of this review is to provide an overview of the current understanding of AF pathophysiology, identify common risk factors, describe prevention strategies, and outline both nonoperative and surgical treatment options. This manuscript will focus specifically on sterile AF of the knee, elbow, and shoulder.</p>","PeriodicalId":49481,"journal":{"name":"Sports Medicine and Arthroscopy Review","volume":"30 1","pages":"29-41"},"PeriodicalIF":1.9,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830598/pdf/nihms-1705837.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9374874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-01DOI: 10.1097/JSA.0000000000000322
Devin P Leland, Ayoosh Pareek, Erik Therrien, Ryan R Wilbur, Michael J Stuart, Aaron J Krych, Bruce A Levy, Christopher L Camp
Arthroscopy of the shoulder, elbow, hip, and knee has become increasingly utilized due to continued advancements in technique, training, and instrumentation. In addition, arthroscopy is generally safe and effective in the utilization of joint preservation surgical techniques. The arthroscopist must utilize a thorough understanding of the surgical anatomy, detailed care with patient positioning, and safe instrumentation portals to prevent associated neurological injury. In the event of postoperative neurological complications, the physician must carefully document the patient history and physical examination while considering the utilization of additional imaging, testing, or surgical nerve exploration with a specialized team depending upon the severity of neurological injury. In this review, we discuss the prevention, evaluation, and treatment of neurological complications related for arthroscopic procedures of the shoulder, elbow, hip, and knee.
{"title":"Neurological Complications Following Arthroscopic and Related Sports Surgery: Prevention, Work-up, and Treatment.","authors":"Devin P Leland, Ayoosh Pareek, Erik Therrien, Ryan R Wilbur, Michael J Stuart, Aaron J Krych, Bruce A Levy, Christopher L Camp","doi":"10.1097/JSA.0000000000000322","DOIUrl":"10.1097/JSA.0000000000000322","url":null,"abstract":"<p><p>Arthroscopy of the shoulder, elbow, hip, and knee has become increasingly utilized due to continued advancements in technique, training, and instrumentation. In addition, arthroscopy is generally safe and effective in the utilization of joint preservation surgical techniques. The arthroscopist must utilize a thorough understanding of the surgical anatomy, detailed care with patient positioning, and safe instrumentation portals to prevent associated neurological injury. In the event of postoperative neurological complications, the physician must carefully document the patient history and physical examination while considering the utilization of additional imaging, testing, or surgical nerve exploration with a specialized team depending upon the severity of neurological injury. In this review, we discuss the prevention, evaluation, and treatment of neurological complications related for arthroscopic procedures of the shoulder, elbow, hip, and knee.</p>","PeriodicalId":49481,"journal":{"name":"Sports Medicine and Arthroscopy Review","volume":"30 1","pages":"e1-e8"},"PeriodicalIF":1.9,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128250/pdf/nihms-1701750.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9374873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-01DOI: 10.1097/JSA.0000000000000331
W Dilworth Cannon
{"title":"Tribute to Kenneth E. DeHaven, MD.","authors":"W Dilworth Cannon","doi":"10.1097/JSA.0000000000000331","DOIUrl":"https://doi.org/10.1097/JSA.0000000000000331","url":null,"abstract":"","PeriodicalId":49481,"journal":{"name":"Sports Medicine and Arthroscopy Review","volume":"29 4","pages":"181"},"PeriodicalIF":1.9,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39839161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-01DOI: 10.1097/JSA.0000000000000333
Leah Carreño, Eliot Thomasma, John Mason, Will Pitt, Michael Crowell
There is a need to improve the quality of rehabilitation in sports medicine to return athletes to optimal function safely and quickly, reducing the risk of reinjury. This paper describes a planning paradigm to guide clinical reasoning during individual treatment sessions and a model for planning the rehabilitation program from acute injury to return to play. The design of a rehabilitation program should be a collaborative, team effort, and accounting for the specific needs of the athlete. As the athlete progresses from acute injury management all the way back to full competition, the rehabilitation professional emphasizes the components of pain management, motion, motor control, and force production in varying degrees based upon phases of tissue healing and the athlete's response. Utilizing high-value, evidence-based treatments maximize both the effectiveness and efficiency of rehabilitation to restore and improve upon preinjury levels of physical performance.
{"title":"Comprehensive Rehabilitation of the Athlete: A Specific and Purposeful Approach.","authors":"Leah Carreño, Eliot Thomasma, John Mason, Will Pitt, Michael Crowell","doi":"10.1097/JSA.0000000000000333","DOIUrl":"https://doi.org/10.1097/JSA.0000000000000333","url":null,"abstract":"<p><p>There is a need to improve the quality of rehabilitation in sports medicine to return athletes to optimal function safely and quickly, reducing the risk of reinjury. This paper describes a planning paradigm to guide clinical reasoning during individual treatment sessions and a model for planning the rehabilitation program from acute injury to return to play. The design of a rehabilitation program should be a collaborative, team effort, and accounting for the specific needs of the athlete. As the athlete progresses from acute injury management all the way back to full competition, the rehabilitation professional emphasizes the components of pain management, motion, motor control, and force production in varying degrees based upon phases of tissue healing and the athlete's response. Utilizing high-value, evidence-based treatments maximize both the effectiveness and efficiency of rehabilitation to restore and improve upon preinjury levels of physical performance.</p>","PeriodicalId":49481,"journal":{"name":"Sports Medicine and Arthroscopy Review","volume":"29 4","pages":"e57-e64"},"PeriodicalIF":1.9,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39839166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-01Epub Date: 2021-11-03DOI: 10.1097/01.jsa.0000801512.82765.80
{"title":"Author Index.","authors":"","doi":"10.1097/01.jsa.0000801512.82765.80","DOIUrl":"https://doi.org/10.1097/01.jsa.0000801512.82765.80","url":null,"abstract":"","PeriodicalId":49481,"journal":{"name":"Sports Medicine and Arthroscopy Review","volume":"29 4","pages":"207"},"PeriodicalIF":1.9,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41167528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-01DOI: 10.1097/JSA.0000000000000326
Jeremy D Ross, Kenneth L Cameron, Brian J Colsant, Megan N Houston
Over the last decade, with emphasis on concussion awareness and potential long-term deficits, concussions have become a public health concern. Although common, concussions are complex in nature and often require a collaborative treatment approach across multiple disciplines. In an athletic setting, the Team Physician plays a critical leadership role in the organization, management, and provision of care for concussed athletes. However, leadership strategies for the provision of concussion care utilized by the Team Physician have not been adequately described. This manuscript intends to describe advanced planning for concussion management and highlight best practices for the provision of care for the concussed athlete, to assist the Team Physician in coordinating optimal care. Specific emphasis will be placed on outlining a concussion management protocol aligned with evidence-based best practices.
{"title":"Leadership Lessons in Concussion Management for Team Physicians.","authors":"Jeremy D Ross, Kenneth L Cameron, Brian J Colsant, Megan N Houston","doi":"10.1097/JSA.0000000000000326","DOIUrl":"10.1097/JSA.0000000000000326","url":null,"abstract":"<p><p>Over the last decade, with emphasis on concussion awareness and potential long-term deficits, concussions have become a public health concern. Although common, concussions are complex in nature and often require a collaborative treatment approach across multiple disciplines. In an athletic setting, the Team Physician plays a critical leadership role in the organization, management, and provision of care for concussed athletes. However, leadership strategies for the provision of concussion care utilized by the Team Physician have not been adequately described. This manuscript intends to describe advanced planning for concussion management and highlight best practices for the provision of care for the concussed athlete, to assist the Team Physician in coordinating optimal care. Specific emphasis will be placed on outlining a concussion management protocol aligned with evidence-based best practices.</p>","PeriodicalId":49481,"journal":{"name":"Sports Medicine and Arthroscopy Review","volume":"29 4","pages":"191-199"},"PeriodicalIF":1.9,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39852589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}