Pub Date : 2025-12-01Epub Date: 2025-12-03DOI: 10.1055/s-0045-1811257
Filip M Vanhoenacker
A swollen finger may be caused by a variety of lesions of different etiologies, such as infection, inflammation, degenerative disorders, crystal diseases, congenital diseases, trauma, and tumors or tumorlike disorders of bone and soft tissues. Following a case presentation of a rare case presenting with a swollen finger, this article reviews the imaging features of the most common etiologies of swelling of the digits.
{"title":"The Swollen Finger: Etiology and Imaging Findings.","authors":"Filip M Vanhoenacker","doi":"10.1055/s-0045-1811257","DOIUrl":"https://doi.org/10.1055/s-0045-1811257","url":null,"abstract":"<p><p>A swollen finger may be caused by a variety of lesions of different etiologies, such as infection, inflammation, degenerative disorders, crystal diseases, congenital diseases, trauma, and tumors or tumorlike disorders of bone and soft tissues. Following a case presentation of a rare case presenting with a swollen finger, this article reviews the imaging features of the most common etiologies of swelling of the digits.</p>","PeriodicalId":49545,"journal":{"name":"Seminars in Musculoskeletal Radiology","volume":"29 6","pages":"923-938"},"PeriodicalIF":1.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-12-03DOI: 10.1055/s-0045-1812069
Rainer Schmitt
{"title":"Hand and Wrist Imaging.","authors":"Rainer Schmitt","doi":"10.1055/s-0045-1812069","DOIUrl":"https://doi.org/10.1055/s-0045-1812069","url":null,"abstract":"","PeriodicalId":49545,"journal":{"name":"Seminars in Musculoskeletal Radiology","volume":"29 6","pages":"825-826"},"PeriodicalIF":1.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Solid soft tissue masses of the hand represent a diverse group of lesions, most of which are benign. Accurate diagnosis is essential to guide management and avoid unnecessary or inappropriate surgical intervention. This review discusses solid soft tissue tumors of the hand in accordance with the 2020 World Health Organization Classification of Soft Tissue Tumors, emphasizing imaging features and clinical presentation, as well as the current European Society of Musculoskeletal Radiology guidelines from 2023 for primary imaging of soft tissue lesions. Characteristic imaging features help diagnose common entities such as lipomas, tenosynovial giant cell tumors, glomus tumors, and nerve sheath tumors. Various pseudolesions (e.g., traumatic neuromas) are also discussed. The importance of referral to specialized sarcoma centers for indeterminant or aggressive lesions is highlighted.
{"title":"Soft Tissue Masses of the Hand.","authors":"Sabine Popp, Iris-Melanie Nöbauer-Huhmann, Suren Jengojan","doi":"10.1055/s-0045-1811637","DOIUrl":"10.1055/s-0045-1811637","url":null,"abstract":"<p><p>Solid soft tissue masses of the hand represent a diverse group of lesions, most of which are benign. Accurate diagnosis is essential to guide management and avoid unnecessary or inappropriate surgical intervention. This review discusses solid soft tissue tumors of the hand in accordance with the 2020 World Health Organization Classification of Soft Tissue Tumors, emphasizing imaging features and clinical presentation, as well as the current European Society of Musculoskeletal Radiology guidelines from 2023 for primary imaging of soft tissue lesions. Characteristic imaging features help diagnose common entities such as lipomas, tenosynovial giant cell tumors, glomus tumors, and nerve sheath tumors. Various pseudolesions (e.g., traumatic neuromas) are also discussed. The importance of referral to specialized sarcoma centers for indeterminant or aggressive lesions is highlighted.</p>","PeriodicalId":49545,"journal":{"name":"Seminars in Musculoskeletal Radiology","volume":"29 6","pages":"894-905"},"PeriodicalIF":1.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12674893/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-12-03DOI: 10.1055/s-0045-1811530
Alvaro Cerezal, João Vieira, Ana Canga, Luis Cerezal
This case-based review explores the biomechanical foundations of the wrist by integrating advanced imaging findings with core anatomical and functional principles. We analyze six representative scenarios: distal radioulnar joint instability, ulnocarpal impaction, unstable triangular fibrocartilage complex tear, scapholunate ligament injury, posttraumatic ulnar translocation of the carpus, and scaphotrapeziotrapezoid osteoarthritis. The cases reviewed here illustrate how static and dynamic stabilizers preserve carpal congruence and load transmission. We highlight the roles of the triangular fibrocartilage complex, the distal interosseous membrane, and the intrinsic and extrinsic ligament systems, along with the kinematic interplay between carpal rows and sensorimotor control mechanisms. We emphasize the value of magnetic resonance imaging, magnetic resonance arthrography, and wrist arthroscopy as essential tools for detecting instability and planning treatment. By applying biomechanical principles to imaging interpretation, we can enhance lesion pattern recognition, support informed surgical decision making, and foster a more effective multidisciplinary approach to wrist pathology.
{"title":"The Biomechanical Basics of Carpal Imaging.","authors":"Alvaro Cerezal, João Vieira, Ana Canga, Luis Cerezal","doi":"10.1055/s-0045-1811530","DOIUrl":"https://doi.org/10.1055/s-0045-1811530","url":null,"abstract":"<p><p>This case-based review explores the biomechanical foundations of the wrist by integrating advanced imaging findings with core anatomical and functional principles. We analyze six representative scenarios: distal radioulnar joint instability, ulnocarpal impaction, unstable triangular fibrocartilage complex tear, scapholunate ligament injury, posttraumatic ulnar translocation of the carpus, and scaphotrapeziotrapezoid osteoarthritis. The cases reviewed here illustrate how static and dynamic stabilizers preserve carpal congruence and load transmission. We highlight the roles of the triangular fibrocartilage complex, the distal interosseous membrane, and the intrinsic and extrinsic ligament systems, along with the kinematic interplay between carpal rows and sensorimotor control mechanisms. We emphasize the value of magnetic resonance imaging, magnetic resonance arthrography, and wrist arthroscopy as essential tools for detecting instability and planning treatment. By applying biomechanical principles to imaging interpretation, we can enhance lesion pattern recognition, support informed surgical decision making, and foster a more effective multidisciplinary approach to wrist pathology.</p>","PeriodicalId":49545,"journal":{"name":"Seminars in Musculoskeletal Radiology","volume":"29 6","pages":"849-862"},"PeriodicalIF":1.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-12-03DOI: 10.1055/s-0045-1811205
Romain Gillet, Samy Obeid, Fatma Boubaker, Nicolas Douis, Maxime Clara, Pierre Gillet, Pedro Augusto Gondim Teixeira, Alain Blum
The distal radioulnar joint is essential for forearm rotation and wrist stability. Instability of the distal radioulnar joint, often resulting from trauma, ligamentous injury, or degeneration, can lead to pain, functional impairment, and progressive joint damage. Accurate diagnosis relies on a thorough imaging assessment due to the complex joint anatomy, especially the triangular fibrocartilage complex.Standard radiographs are useful to evaluate bone alignment but have limited soft tissue sensitivity. Ultrasound provides dynamic real-time assessment of superficial structures, although it is operator dependent. Computed tomography offers excellent spatial resolution for bony abnormalities and joint congruity, with a static and pseudo-dynamic approach, considered the gold standard.Magnetic resonance imaging is the reference standard for soft tissue evaluation, particularly the triangular fibrocartilage complex and surrounding ligaments. Emerging dynamic imaging techniques, including real-time magnetic resonance imaging and four-dimensional computed tomography, allow visualization of joint kinematics and detection of subtle instabilities not seen on static images. This review outlines the role of each modality in assessing distal radioulnar joint instability.
{"title":"Imaging of Distal Radioulnar Joint Focused on Four-dimensional Computed Tomography: Toward a New Imaging Standard?","authors":"Romain Gillet, Samy Obeid, Fatma Boubaker, Nicolas Douis, Maxime Clara, Pierre Gillet, Pedro Augusto Gondim Teixeira, Alain Blum","doi":"10.1055/s-0045-1811205","DOIUrl":"https://doi.org/10.1055/s-0045-1811205","url":null,"abstract":"<p><p>The distal radioulnar joint is essential for forearm rotation and wrist stability. Instability of the distal radioulnar joint, often resulting from trauma, ligamentous injury, or degeneration, can lead to pain, functional impairment, and progressive joint damage. Accurate diagnosis relies on a thorough imaging assessment due to the complex joint anatomy, especially the triangular fibrocartilage complex.Standard radiographs are useful to evaluate bone alignment but have limited soft tissue sensitivity. Ultrasound provides dynamic real-time assessment of superficial structures, although it is operator dependent. Computed tomography offers excellent spatial resolution for bony abnormalities and joint congruity, with a static and pseudo-dynamic approach, considered the gold standard.Magnetic resonance imaging is the reference standard for soft tissue evaluation, particularly the triangular fibrocartilage complex and surrounding ligaments. Emerging dynamic imaging techniques, including real-time magnetic resonance imaging and four-dimensional computed tomography, allow visualization of joint kinematics and detection of subtle instabilities not seen on static images. This review outlines the role of each modality in assessing distal radioulnar joint instability.</p>","PeriodicalId":49545,"journal":{"name":"Seminars in Musculoskeletal Radiology","volume":"29 6","pages":"827-841"},"PeriodicalIF":1.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-12-03DOI: 10.1055/s-0045-1811699
Matthias Bollow, Rainer Schmitt
The general term collagenosis covers a group of connective tissue diseases triggered by systemic autoimmune processes and as yet unknown trigger mechanisms. Systemic sclerosis is one of the five types of collagenosis. Of the systemic rheumatic diseases, it has the highest mortality rate, partly due to the historical lack of disease-modifying therapies. Early diagnosis of systemic sclerosis can be challenging if the typical symptoms and diagnostic or classification criteria are not yet evident. However, given the disease's often heterogeneous course, early diagnosis and treatment are crucial for prognosis and to protect against progression involving the internal organs. Because reliable and prognostically valid biomarkers are generally lacking, deciding whether or not to pursue aggressive treatment in the early stages of the disease remains problematic. This article discusses the potential benefits of imaging techniques such as magnetic resonance imaging and pharmacoangiography for the early diagnosis of systemic sclerosis.
{"title":"Imaging Capabilities of Patients with Early-stage Collagenoses.","authors":"Matthias Bollow, Rainer Schmitt","doi":"10.1055/s-0045-1811699","DOIUrl":"https://doi.org/10.1055/s-0045-1811699","url":null,"abstract":"<p><p>The general term <i>collagenosis</i> covers a group of connective tissue diseases triggered by systemic autoimmune processes and as yet unknown trigger mechanisms. Systemic sclerosis is one of the five types of collagenosis. Of the systemic rheumatic diseases, it has the highest mortality rate, partly due to the historical lack of disease-modifying therapies. Early diagnosis of systemic sclerosis can be challenging if the typical symptoms and diagnostic or classification criteria are not yet evident. However, given the disease's often heterogeneous course, early diagnosis and treatment are crucial for prognosis and to protect against progression involving the internal organs. Because reliable and prognostically valid biomarkers are generally lacking, deciding whether or not to pursue aggressive treatment in the early stages of the disease remains problematic. This article discusses the potential benefits of imaging techniques such as magnetic resonance imaging and pharmacoangiography for the early diagnosis of systemic sclerosis.</p>","PeriodicalId":49545,"journal":{"name":"Seminars in Musculoskeletal Radiology","volume":"29 6","pages":"915-922"},"PeriodicalIF":1.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-12-03DOI: 10.1055/s-0045-1811587
Torsten Diekhoff, Sevtap Tugce Ulas
Crystal arthropathies of the hand encompass a wide spectrum of disorders characterized by the deposition of various crystals within joints and soft tissues, often leading to inflammatory and degenerative changes. Due to their ability to mimic other rheumatic diseases, accurate diagnosis is challenging and relies heavily on imaging. This review highlights the pathophysiologic features and typical manifestations of key crystal arthropathies-calcium pyrophosphate crystal deposition, gout, hydroxyapatite deposition disease, oxalosis, amyloidosis, and rare mimickers such as ochronosis-focusing on their radiologic appearances. Emphasis is placed on the strengths and limitations of different imaging modalities, particularly radiography, ultrasound, computed tomography, magnetic resonance imaging, and dual-energy computed tomography, in detecting both crystal deposits and associated inflammatory activity. Understanding these imaging patterns is essential for an appropriate differential diagnosis and clinical management.
{"title":"Different Facets of Crystal Arthropathies of the Hand.","authors":"Torsten Diekhoff, Sevtap Tugce Ulas","doi":"10.1055/s-0045-1811587","DOIUrl":"https://doi.org/10.1055/s-0045-1811587","url":null,"abstract":"<p><p>Crystal arthropathies of the hand encompass a wide spectrum of disorders characterized by the deposition of various crystals within joints and soft tissues, often leading to inflammatory and degenerative changes. Due to their ability to mimic other rheumatic diseases, accurate diagnosis is challenging and relies heavily on imaging. This review highlights the pathophysiologic features and typical manifestations of key crystal arthropathies-calcium pyrophosphate crystal deposition, gout, hydroxyapatite deposition disease, oxalosis, amyloidosis, and rare mimickers such as ochronosis-focusing on their radiologic appearances. Emphasis is placed on the strengths and limitations of different imaging modalities, particularly radiography, ultrasound, computed tomography, magnetic resonance imaging, and dual-energy computed tomography, in detecting both crystal deposits and associated inflammatory activity. Understanding these imaging patterns is essential for an appropriate differential diagnosis and clinical management.</p>","PeriodicalId":49545,"journal":{"name":"Seminars in Musculoskeletal Radiology","volume":"29 6","pages":"906-914"},"PeriodicalIF":1.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-12-03DOI: 10.1055/s-0045-1809693
Michele A Riva
This history page in the series "Leaders in Musculoskeletal Radiology" is dedicated to the memory and achievements of the German radiologist Alban Köhler (1874-1947), whose name is immortalized in several eponymous conditions, including Köhler's disease I and II. His pioneering work in skeletal imaging and his meticulous approach to radiographic analysis have left an enduring legacy in the field of musculoskeletal radiology.
{"title":"Leaders in MSK Radiology: Alban Köhler, 1874-1947.","authors":"Michele A Riva","doi":"10.1055/s-0045-1809693","DOIUrl":"https://doi.org/10.1055/s-0045-1809693","url":null,"abstract":"<p><p>This history page in the series \"Leaders in Musculoskeletal Radiology\" is dedicated to the memory and achievements of the German radiologist Alban Köhler (1874-1947), whose name is immortalized in several eponymous conditions, including Köhler's disease I and II. His pioneering work in skeletal imaging and his meticulous approach to radiographic analysis have left an enduring legacy in the field of musculoskeletal radiology.</p>","PeriodicalId":49545,"journal":{"name":"Seminars in Musculoskeletal Radiology","volume":"29 6","pages":"963-964"},"PeriodicalIF":1.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-12-03DOI: 10.1055/s-0045-1811586
Thomas Bayer
Flexor tendon pathologies of the hand are frequently encountered in musculoskeletal radiology and require a precise diagnosis and treatment due to the complexity of the anatomy. Typical conditions are acute traumatic injuries such as tendon and/or pulley rupture as well as open lacerations. In addition, there is a wide range of infectious diseases, chronic overuse conditions, as well as degenerative, neoplastic, and systemic/rheumatic tendon disorders. Accurate characterization of these lesions with ultrasound for basic diagnostics and magnetic resonance imaging for further clarification is crucial for optimal therapy management and prognosis. Following a patient presentation, this article reviews the anatomy and diagnostic imaging features of the most common flexor tendon pathologies.
{"title":"Lesions of the Flexor Tendons at the Hand.","authors":"Thomas Bayer","doi":"10.1055/s-0045-1811586","DOIUrl":"https://doi.org/10.1055/s-0045-1811586","url":null,"abstract":"<p><p>Flexor tendon pathologies of the hand are frequently encountered in musculoskeletal radiology and require a precise diagnosis and treatment due to the complexity of the anatomy. Typical conditions are acute traumatic injuries such as tendon and/or pulley rupture as well as open lacerations. In addition, there is a wide range of infectious diseases, chronic overuse conditions, as well as degenerative, neoplastic, and systemic/rheumatic tendon disorders. Accurate characterization of these lesions with ultrasound for basic diagnostics and magnetic resonance imaging for further clarification is crucial for optimal therapy management and prognosis. Following a patient presentation, this article reviews the anatomy and diagnostic imaging features of the most common flexor tendon pathologies.</p>","PeriodicalId":49545,"journal":{"name":"Seminars in Musculoskeletal Radiology","volume":"29 6","pages":"951-958"},"PeriodicalIF":1.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-12-03DOI: 10.1055/s-0045-1811258
Nina Hesse, Rainer Schmitt, Hannah Gildein, Elisabeth M Haas-Lützenberger, Paul Luca Reidler
The recently introduced CUP classification of the triangular fibrocartilage complex divides the lesions into central (C), ulnar (U), and peripheral (P). The periphery of the triangular fibrocartilage complex consists of the meniscus homologue, the ulnocarpal joint capsule including the extensor carpi ulnaris tendon sheath, and the ulnotriquetral and ulnolunate ligaments. Peripheral triangular fibrocartilage complex lesions can occur in isolation or in combination with injuries of the ulnar insertions and/or the articular disk. Most commonly the meniscus homologue and dorsal capsule are affected. Magnetic resonance imaging and computed tomography/magnetic arthrography are used to assess peripheral lesions. The arthroscopic assessment of peripheral triangular fibrocartilage complex lesions is limited. To date, data on the clinical relevance of the radiologic reporting of peripheral lesions are lacking. This pictorial review illustrates typical peripheral lesions of the triangular fibrocartilage complex according to the CUP classification.
{"title":"Peripheral Lesions of the Triangular Fibrocartilage Complex.","authors":"Nina Hesse, Rainer Schmitt, Hannah Gildein, Elisabeth M Haas-Lützenberger, Paul Luca Reidler","doi":"10.1055/s-0045-1811258","DOIUrl":"https://doi.org/10.1055/s-0045-1811258","url":null,"abstract":"<p><p>The recently introduced CUP classification of the triangular fibrocartilage complex divides the lesions into central (C), ulnar (U), and peripheral (P). The periphery of the triangular fibrocartilage complex consists of the meniscus homologue, the ulnocarpal joint capsule including the extensor carpi ulnaris tendon sheath, and the ulnotriquetral and ulnolunate ligaments. Peripheral triangular fibrocartilage complex lesions can occur in isolation or in combination with injuries of the ulnar insertions and/or the articular disk. Most commonly the meniscus homologue and dorsal capsule are affected. Magnetic resonance imaging and computed tomography/magnetic arthrography are used to assess peripheral lesions. The arthroscopic assessment of peripheral triangular fibrocartilage complex lesions is limited. To date, data on the clinical relevance of the radiologic reporting of peripheral lesions are lacking. This pictorial review illustrates typical peripheral lesions of the triangular fibrocartilage complex according to the CUP classification.</p>","PeriodicalId":49545,"journal":{"name":"Seminars in Musculoskeletal Radiology","volume":"29 6","pages":"842-848"},"PeriodicalIF":1.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}