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Metabolic Bone Diseases: Recommendations for Interventional Radiology. 代谢性骨病:对介入放射学的建议。
IF 0.9 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-10-01 Epub Date: 2024-10-15 DOI: 10.1055/s-0044-1788580
Antonio Di Donna, Salvatore Masala, Gianluca Muto, Stefano Marcia, Flavio Giordano, Mario Muto

Metabolic bone diseases (MBDs), including osteoporosis, osteomalacia, and Paget's disease, represent a significant challenge in medical imaging and intervention. Interventional radiologists play a pivotal role in managing these conditions, due to the crucial role of detailed and precise imaging in diagnosing and treating MBDs. This article offers comprehensive recommendations aimed at optimizing interventional radiologic practices for patients with MBDs, highlighting the importance of using advanced imaging modalities, including dual-energy X-ray absorptiometry and magnetic resonance imaging, essential for accurate assessment of bone mineral density and architecture, guiding effective intervention strategies. We also discuss the use of minimally invasive procedures like vertebroplasty and biopsy, vital for both diagnostic and therapeutic purposes, to enhance diagnostic accuracy and therapeutic outcomes, ensuring high-quality patient management in the context of MBDs.

代谢性骨病(MBDs),包括骨质疏松症、骨软化症和帕吉特氏病,是医学影像和介入治疗的重大挑战。由于详细而精确的成像在诊断和治疗代谢性骨病方面起着至关重要的作用,因此介入放射科医生在管理这些疾病方面发挥着举足轻重的作用。本文提出了旨在优化 MBD 患者介入放射疗法的全面建议,强调了使用先进成像模式(包括双能 X 射线吸收测量法和磁共振成像)的重要性,这对于准确评估骨矿物质密度和结构、指导有效的介入策略至关重要。我们还讨论了微创手术(如椎体成形术和活检)的使用,这对诊断和治疗都至关重要,可提高诊断准确性和治疗效果,确保对 MBD 患者进行高质量的管理。
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引用次数: 0
Imaging of Metabolic Bone Diseases. 代谢性骨病的成像。
IF 0.9 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-10-01 Epub Date: 2024-10-15 DOI: 10.1055/s-0044-1789256
Alberto Bazzocchi, Giuseppe Guglielmi
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引用次数: 0
Radiofrequency Echographic Multi-Spectrometry in the Diagnosis of Metabolic Bone Disease. 射频超声多谱勒诊断代谢性骨病。
IF 0.9 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-10-01 Epub Date: 2024-10-15 DOI: 10.1055/s-0044-1788885
Rossella Gifuni, Manuela Montatore, Riccardo Guglielmi, Alberto Bazzocchi, Carmelo Messina, Giuseppe Guglielmi

Dual-energy X-ray absorptiometry (DXA) and bone mineral density (BMD) pose several limitations in some patient categories, such as pregnant women and young people. This review article explores whether the innovative radiofrequency echographic multi-spectrometry (REMS) technology is beneficial for assessing the bone condition of various patient groups. Common consequences in patients with acromegalia, prostate cancer undergoing hormone therapy, osteogenesis imperfecta, anorexia nervosa, and in a peritoneal dialysis setting include decreased BMD and an increased risk of fragility fracture.DXA is currently regarded as the gold standard for BMD assessment. However, using the DXA technique has several drawbacks in a young patient who requires repeated BMD tests because it uses ionizing radiation. Because of its precision and consistency, the REMS technique may be a valuable tool to assess changes in bone condition in patients of all ages, particularly in female patients who are fertile or who are pregnant or nursing.

双能 X 射线吸收测量法(DXA)和骨矿物质密度(BMD)在某些患者类别中存在一些局限性,如孕妇和年轻人。这篇综述文章探讨了创新的射频回声多谱勒技术(REMS)是否有利于评估不同患者群体的骨质状况。肢端肥大症患者、接受激素治疗的前列腺癌患者、成骨不全症患者、神经性厌食症患者以及腹膜透析患者的常见后果包括 BMD 减少和脆性骨折风险增加。然而,对于需要反复进行 BMD 测试的年轻患者来说,使用 DXA 技术有几个缺点,因为它使用了电离辐射。由于其精确性和一致性,REMS 技术可能是评估各年龄段患者骨质状况变化的重要工具,尤其是对生育期、妊娠期或哺乳期的女性患者。
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引用次数: 0
Magnetic Resonance Assessment of Bone Quality in Metabolic Bone Diseases. 代谢性骨病的骨质磁共振评估
IF 0.9 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-10-01 Epub Date: 2024-10-15 DOI: 10.1055/s-0044-1788693
Nico Sollmann, Michael Dieckmeyer, Julio Carballido-Gamio, Anh Tu Van, Dimitrios C Karampinos, Georg C Feuerriegel, Sarah C Foreman, Alexandra S Gersing, Roland Krug, Thomas Baum, Jan S Kirschke

Metabolic bone diseases (MBDs) are a diverse group of diseases, affecting the mass or structure of bones and leading to reduced bone quality. Parameters representing different aspects of bone health can be obtained from various magnetic resonance imaging (MRI) methods such as proton MR spectroscopy, as well as chemical shift encoding-based water-fat imaging, that have been frequently applied to study bone marrow in particular. Furthermore, T2* mapping and high-resolution trabecular bone imaging have been implemented to study bone microstructure. In addition, quantitative susceptibility mapping and ultrashort echo time imaging are used for trabecular and cortical bone assessment. This review offers an overview of technical aspects, as well as major clinical applications and derived main findings, for MRI-based assessment of bone quality in MBDs. It focuses on osteoporosis as the most common MBD.

代谢性骨病(MBDs)是一类多种多样的疾病,会影响骨骼的质量或结构,导致骨骼质量下降。代表骨骼健康不同方面的参数可通过各种磁共振成像(MRI)方法获得,如质子磁共振波谱以及基于化学位移编码的水脂成像,这些方法已被频繁用于研究骨髓。此外,T2*映射和高分辨率骨小梁成像已被用于研究骨的微观结构。此外,定量易感性成像和超短回波时间成像也用于骨小梁和骨皮质的评估。本综述概述了基于磁共振成像评估 MBD 骨质的技术方面、主要临床应用和衍生的主要发现。重点关注最常见的 MBD--骨质疏松症。
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引用次数: 0
Congenital and Traumatic Conditions of the Pediatric Hand: Overview for the Radiologist. 小儿手部的先天性和外伤性疾病:放射科医生概述。
IF 0.9 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-01 Epub Date: 2024-07-29 DOI: 10.1055/s-0044-1779716
J Herman Kan, Olivia A Barron, Bryce R Bell

Alignment, longitudinal growth, and function of the musculoskeletal unit of the pediatric hand is complex due to the combination of open growth plates, ossification variations, and their relationship with finger tendinous and ligamentous attachments. This review presents the basics of normal development, acquired and congenital variations, and traumatic conditions of the pediatric hand from the perspective of the pediatric musculoskeletal radiologist and hand surgeon. This multimodality imaging article focuses on non-oncologic and non-rheumatologic conditions of the pediatric hand, inclusive of fingers, thumb, and metacarpal bones.

由于生长板开放、骨化变异及其与手指肌腱和韧带附着的关系,小儿手部肌肉骨骼单元的排列、纵向生长和功能非常复杂。这篇综述从小儿肌肉骨骼放射科医生和手外科医生的角度,介绍了小儿手部正常发育、后天和先天变异以及创伤情况的基本知识。这篇多模态成像文章的重点是小儿手部的非肿瘤性和非风湿性疾病,包括手指、拇指和掌骨。
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引用次数: 0
Imaging of Disease and Normal Variant Patterns in Pediatric Hips. 小儿髋关节疾病和正常变异模式的成像。
IF 0.9 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-01 Epub Date: 2024-07-29 DOI: 10.1055/s-0044-1786153
Jade A Anderson, Nicholas Laucis, John Symanski, Donna Blankenbaker

The pediatric hip undergoes significant changes from infancy through adolescence. Proper maturation is crucial for the development of a stable and functional hip joint. Imaging interpretation of the pediatric hip requires distinguishing normal variants and maturation patterns from pathology. We review femoral ossification centers, variants, and conditions that affect the proximal femur, such as Legg-Calvé-Perthes disease; the acetabulum, such as developmental hip dysplasia; the acetabular labrum, such as femoroacetabular impingement; and synovial pathology in children through adolescence. Understanding the spectrum of hip conditions and using advanced imaging techniques are essential for the accurate diagnosis and effective management of pediatric hip disorders.

从婴儿期到青春期,小儿髋关节会发生重大变化。适当的成熟对髋关节的稳定和功能发育至关重要。对小儿髋关节的影像解读需要区分正常变异和成熟模式与病理。我们将回顾股骨骨化中心、变异以及影响股骨近端(如 Legg-Calvé-Perthes 病)、髋臼(如发育性髋关节发育不良)、髋臼唇(如股骨髋臼撞击症)和儿童至青春期滑膜病变的情况。要准确诊断和有效治疗小儿髋关节疾病,就必须了解髋关节疾病的范围并使用先进的成像技术。
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引用次数: 0
Pediatric Shoulder Girdle. 小儿肩腰带
IF 0.9 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-01 Epub Date: 2024-07-29 DOI: 10.1055/s-0044-1779717
Mobeen Farooq, Jeffrey A Belair, Vishal Desai

The pediatric shoulder girdle is a complex anatomical structure uniting the upper extremity and trunk. The osseous structures, their articulations, and the surrounding soft tissue support structures (muscles, tendons, and ligaments) allow for a wide range of motion at the shoulder. Growth and maturation of the components at the shoulder girdle vary, particularly the osseous structures. This characteristic renders interpretation of imaging of the pediatric shoulder girdle more challenging because normal or variant anatomy can be confused for pathology. We review the physiologic growth and maturation of the shoulder girdle with special emphasis on the development of the bones and their articulations. The role of various imaging modalities and the common osseous and soft tissue variants in the pediatric shoulder are also discussed.

小儿肩部是连接上肢和躯干的复杂解剖结构。骨性结构、它们之间的衔接以及周围的软组织支撑结构(肌肉、肌腱和韧带)使得肩部的活动范围很广。肩部各组成部分的生长和成熟情况各不相同,尤其是骨性结构。由于正常或变异的解剖结构可能会与病理结构相混淆,因此这一特点使得对小儿肩腰部成像的解读更具挑战性。我们回顾了肩腰部的生理生长和成熟过程,特别强调了骨骼及其关节的发育。我们还讨论了各种成像模式的作用以及小儿肩部常见的骨性和软组织变异。
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引用次数: 0
The Pediatric Ankle: Normal Variations and Maturation-Dependent Pathology. 小儿踝关节:正常变化和成熟期病理变化。
IF 0.9 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-01 Epub Date: 2024-07-29 DOI: 10.1055/s-0044-1779247
Philip G Colucci, Carolyn M Sofka

The pediatric ankle can present a broad range of normal variation and pathology unique to certain stages of development. Understanding the expected age ranges of ossification and fusion about the ankle is essential to provide accurate diagnoses regarding skeletal integrity. This conclusion has been well characterized radiographically and is supported by cadaveric research.The range of appearances on magnetic resonance imaging has also been well described. Knowledge about the structure of the periosteum and perichondrium aids in image interpretation as well as explaining typical injury patterns. The expected appearance of the physis and regional bone marrow signal is also of utmost importance.Ultrasonography is a valuable tool in pediatric musculoskeletal imaging but is limited when there is concern for intra-articular pathology. Computed tomography tends to be reserved for preoperative evaluation. We describe normal variation and maturation-dependent pathology of the pediatric ankle with an emphasis on imaging considerations.

小儿踝关节在某些发育阶段会出现广泛的正常变化和特有的病理变化。了解踝关节骨化和融合的预期年龄范围对于准确诊断骨骼完整性至关重要。这一结论在影像学上有很好的描述,并得到尸体研究的支持。对骨膜和软骨周围结构的了解有助于图像判读和解释典型的损伤模式。超声波检查是小儿肌肉骨骼成像的重要工具,但在担心关节内病变时会受到限制。计算机断层扫描通常用于术前评估。我们介绍了小儿踝关节的正常变化和成熟期病理变化,重点是成像方面的注意事项。
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引用次数: 0
Skeletal Manifestations of Gaucher's Disease: A Case Report and Literature Review. 戈谢病的骨骼表现:病例报告与文献综述
IF 0.9 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-01 Epub Date: 2024-07-29 DOI: 10.1055/s-0044-1782205
Rahma Nour Eldin Saad Mohamed, Walid A Elnahal, Cleofina Furtado, Rania Zeitoun, Nagui Abdel-Wahab

Gaucher's disease (GD) is a lysosomal storage disorder characterized by the storage of glucosylceramide in macrophages ("Gaucher cells"), mainly in the reticuloendothelial system. GD type 1 (GD1) is the most common phenotype that usually manifests with hepatosplenomegaly, cytopenias, and bone involvement. Skeletal manifestations are the most debilitating characteristic and result in significant morbidities. We describe a case of GD1, first presented by a nontraumatic bone fracture. The case presentation highlights the importance of considering GD among the differential diagnosis of nontraumatic fractures, avascular necrosis, and infarcts of the bones. Early diagnosis and treatment improve the course of disease and avoid irreversible sequelae.

戈谢病(GD)是一种溶酶体贮积症,其特征是葡萄糖醛酸酰胺贮存在巨噬细胞("戈谢细胞")中,主要存在于网状内皮系统中。GD 1 型(GD1)是最常见的表型,通常表现为肝脾肿大、细胞减少和骨骼受累。骨骼表现是最令人衰弱的特征,会导致严重的发病。我们描述了一例 GD1 病例,该病例首先表现为非创伤性骨折。该病例突出表明,在非创伤性骨折、血管性坏死和骨梗死的鉴别诊断中考虑 GD 的重要性。早期诊断和治疗可改善病程,避免不可逆转的后遗症。
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引用次数: 0
Pediatric Musculoskeletal Variants. 小儿肌肉骨骼变异。
IF 0.9 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-01 Epub Date: 2024-07-29 DOI: 10.1055/s-0044-1786697
Jie C Nguyen, Adam C Zoga
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引用次数: 0
期刊
Seminars in Musculoskeletal Radiology
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