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South African Journal of Obstetrics and Gynaecology最新文献

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The use of the cerebroplacental ratio in the latent phase of labour to predict adverse outcomes in a resource-limited setting 在资源有限的环境中,利用分娩潜伏期的脑胎盘比率预测不良结果
Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2020-12-15 DOI: 10.7196/SAJOG.1590
A. Wise, E. Nicolaou, H. Lombaard
Background. Risk stratification of pregnant women may decrease the perinatal mortality rate in South Africa. This relies on the assessment of the referring health facility and timeous presentation of the patient. Inaccurate dating affects the ability to detect growth restriction. Patients requiring referral may go undetected and deliver with the inappropriate level of care. Doppler studies can assist in detecting at-risk fetuses.  Objectives. To describe the short-term outcomes of fetuses with a normal or abnormal cerebroplacental ratio (CPR) according to the various definitions in the literature.  Methods. A cohort of 200 pregnant women were prospectively recruited while in early labour. Patient history including previous ultrasound scans were obtained. Ultrasound was done for biometry, umbilical artery (UA), middle cerebral artery (MCA) and uterine Dopplers, and the CPR was calculated. Labour and delivery details were recorded. An association between an abnormal CPR, adverse outcomes and composite score was determined.  Results. Less than a tenth (7.7%; n =15) of the participants had a CPR <1.08. Furthermore, 16.5% ( n =31) of the participants were <5th centile and 24.2% ( n =47) were <10th centile. The composite score of adverse outcomes in those with and without a CPR <5 th centile was not significant ( p =0.737). There was no association between adverse outcomes ( p =0.179) or a composite score ( p =0.237) and the CPR cut-off of the 10th centile. Moreover, there was no association between an abnormal CPR and adverse outcomes after adjusting for confounders. There were no cases of perinatal death or neonatal encephalopathy.  Conclusion. An abnormal CPR was not clinically useful in detecting fetuses at risk of adverse outcomes in early labour regardless of the CPR cut-off. However, this is reassuring when normal and may if combined with other parameters still prove useful.
背景在南非,孕妇的风险分层可能会降低围产期死亡率。这取决于对转诊医疗机构的评估和对患者的及时介绍。年代测定不准确会影响检测生长限制的能力。需要转诊的患者可能未被发现,并提供了不适当的护理水平。多普勒研究可以帮助检测高危胎儿。目标。根据文献中的各种定义,描述脑胎盘比率正常或异常的胎儿的短期结果。方法。前瞻性地招募了200名处于早产期的孕妇。获取患者病史,包括之前的超声扫描。对生物测量、脐动脉(UA)、大脑中动脉(MCA)和子宫多普勒进行超声检查,并计算CPR。记录了劳动力和交付细节。确定了异常心肺复苏、不良反应和综合评分之间的相关性。结果。不到十分之一(7.7%;n=15)的参与者心肺复苏<1.08。此外,16.5%(n=31)的参与者<第5百分位数,24.2%(n=47)的参与者小于第10百分位数。有和没有心肺复苏术的患者的不良反应综合评分均不显著(p=0.737)。不良反应(p=0.179)或综合评分(p=0.237)与第10个百分位数的心肺复苏临界值之间没有关联。此外,在校正混杂因素后,异常心肺复苏与不良结果之间没有关联。没有围产期死亡或新生儿脑病的病例。结论。无论心肺复苏术的截止时间如何,异常心肺复苏在早期分娩中检测有不良后果风险的胎儿方面在临床上都没有用处。然而,这在正常情况下是令人放心的,如果与其他参数相结合,可能仍然有用。
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引用次数: 0
Ruptured renal artery aneurysm in pregnancy 妊娠期肾动脉瘤破裂
Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2020-12-15 DOI: 10.7196/SAJOG.1552
N. Mdlalose, T. L. Khumalo
Renal artery aneurysm is a rare condition, the incidence being ~0.01 - 1%. In pregnancy this condition is rare but carries a significant mortality. Predisposing factors in pregnancy are thought to be physiological, hormonal and haemodynamic. Clinical diagnosis requires a high level of suspicion, as patients are usually asymptomatic prior to rupture. The clinical presentation often mimics other common obstetric conditions such as labour, uterine rupture or placental abruption. It is essential at laparotomy in cases of intra-abdominal bleeding that a thorough search is made for the source of blood loss when no obvious obstetric cause is found. We report a case of a maternal death that was due to rupture of a renal artery aneurysm in the immediate peripartum period in a patient with chronic hypertension.
肾动脉瘤是一种罕见的疾病,发病率约为0.01-1%。在怀孕期间,这种情况很少见,但死亡率很高。妊娠期的易感因素被认为是生理、激素和血液动力学因素。临床诊断需要高度怀疑,因为患者在破裂前通常没有症状。临床表现通常模仿其他常见的产科疾病,如分娩、子宫破裂或胎盘早剥。在腹腔内出血的剖腹手术中,当没有发现明显的产科原因时,彻底寻找出血源是至关重要的。我们报告了一例慢性高血压患者在分娩初期因肾动脉瘤破裂而死亡的产妇。
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引用次数: 0
Beckwith-Wiedemann syndrome associated with congenital cytomegalovirus in an HIV-exposed neonate HIV暴露新生儿Beckwith-Wiedemann综合征与先天性巨细胞病毒相关性研究
Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2020-12-15 DOI: 10.7196/SAJOG.1595
K. Sprong, C. Wright, M. Mabenge, S. Govender
Congenital cytomegalovirus (CMV) infection is associated with preterm birth and congenital abnormalities, which could be exacerbated by maternal co-infection with HIV. This case report describes an HIV-exposed neonate with Beckwith-Wiedemann syndrome (BWS), born by a mother who had a CMV infection of the placenta, who demised following laparoscopic repair of an omphalocele.
先天性巨细胞病毒(CMV)感染与早产和先天性异常有关,而母体合并感染艾滋病毒可加重早产和先天性异常。本病例报告描述了一个hiv暴露的新生儿Beckwith-Wiedemann综合征(BWS),其母亲胎盘有巨细胞病毒感染,在腹腔镜下修复脐膨出后死亡。
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引用次数: 0
Medication adherence in HIV-positive pregnant women on antiretroviral therapy attending antenatal clinics in Ado metropolis, south-west Nigeria: A multicentre study 尼日利亚西南部阿多大都市产前诊所接受抗逆转录病毒治疗的HIV阳性孕妇的药物依从性:一项多中心研究
Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2020-12-15 DOI: 10.7196/SAJOG.1611
O. P. Aduloju, T. Aduloju, I. Ade-Ojo, A. Akintayo
Background. Adherence to antiretroviral therapy (ART) and optimal viral suppression are crucial to the prevention of mother-to-child transmission (PMTCT) of HIV/AIDS.  Objective. To determine adherence to ART and associated factors in Ado-Ekiti, Nigeria.  Methods. A cross-sectional multicentre study was conducted among 170 HIV-positive pregnant women attending antenatal clinics of Ekiti State University Teaching Hospital and the Comprehensive Health Centre in Ado-Ekiti. Data collected using a semi-structured questionnaire were analysed with SPSS. Descriptive statistics, univariate and logistic regression were performed to determine factors associated with good adherence.  Results. Using the pill count method and the Morisky Medication Adherence Scale-8 (MMAS-8), the prevalence of good adherence was 73.5% and 75.3%, respectively. Women with higher education were three times more likely to practise good adherence than those with little or no formal education (adjusted odds ratio (aOR)=3.03; 95% confidence interval (CI) 1.23 - 5.79; p =0.043) and those employed were four times more likely to practise good adherence (aOR=4.13; 95% CI 1.83 - 8.15; p =0.02). Also, partner disclosure, treatment support and use of ARVs for prevention of mother-to-child transmission (PMTCT) were indications of women three times more likely to practise good adherence ((aOR=2.53; 95% CI 0.99 - 5.80; p =0.035); (aOR=2.15; 95% CI 0.77 - 4.15; p =0.014) and (aOR=3.15; 95% CI 0.93 - 6.21; p =0.035)). Forgetfulness, busy schedule and stigmatisation were reasons given for non-adherence.  Conclusions. The majority of the women had good adherence. However, counselling on adherence and partner disclosure should be sustained to ensure full benefits of PMTCT.
背景。坚持抗逆转录病毒治疗(ART)和最佳病毒抑制对预防艾滋病毒/艾滋病母婴传播(PMTCT)至关重要。目标。确定尼日利亚Ado-Ekiti地区抗逆转录病毒治疗依从性及相关因素。方法。对在埃基蒂州立大学教学医院产前诊所和阿多埃基蒂综合保健中心就诊的170名艾滋病毒阳性孕妇进行了一项横断面多中心研究。采用半结构化问卷收集的数据用SPSS进行分析。采用描述性统计、单变量和逻辑回归来确定与良好依从性相关的因素。结果。采用药片计数法和Morisky用药依从性量表-8 (MMAS-8),良好依从率分别为73.5%和75.3%。受过高等教育的妇女比受过很少或没有受过正规教育的妇女更有可能保持良好的依从性(调整优势比(aOR)=3.03;95%置信区间(CI) 1.23 ~ 5.79;p =0.043),而那些被雇佣的人更有可能保持良好的依从性(aOR=4.13;95% ci 1.83 - 8.15;p = 0.02)。此外,伴侣信息披露、治疗支持和使用抗逆转录病毒药物预防母婴传播(PMTCT)是妇女良好依从性的三倍(aOR=2.53;95% ci 0.99 - 5.80;p = 0.035);(aOR = 2.15;95% ci 0.77 - 4.15;p =0.014), (aOR=3.15;95% ci 0.93 - 6.21;p = 0.035)。健忘、繁忙的日程和耻辱是不遵守规定的原因。结论。大多数妇女都有良好的依从性。然而,应该持续进行依从性和伴侣披露方面的咨询,以确保预防母婴传播的充分益处。
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引用次数: 1
The spectrum of placental pathology in a public v. private laboratory practice in Gauteng Province, South Africa 南非豪登省公共与私人实验室实践中的胎盘病理学谱
Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2020-12-15 DOI: 10.7196/SAJOG.1599
M. Savage-Reid, C. Wright, R. Wadee
Background. Laboratory information systems have a wealth of patient and health data that can be made available for research. These data can serve to better inform healthcare delivery and formulation of policies. The placenta is just one histopathology laboratory specimen that can provide such insight, particularly with regard to maternal and neonatal healthcare.  Objectives. To describe the spectrum of placental pathology in a private and public laboratory and to ascertain implications for improved maternal and neonatal healthcare and policies.  Methods. We conducted a retrospective descriptive study of placental histopathology reports from Lancet Laboratories and the National Health Laboratory Service (NHLS) in Johannesburg over a 1-year period (August 2017 - July 2018). The reports were categorised according to the 2014 Amsterdam Placental Workshop Group Consensus Statement and the percentages of each diagnostic entity compared between the two laboratories. These diagnostic categories included ascending infection, maternal vascular malperfusion (MVM), fetal vascular malperfusion, haematogenous infection, chronic villitis of unknown aetiology, retroplacental haemorrhage, no specific pathological changes and ‘other’. Differences in maternal age and gestational age were also compared.  Results. There were 1 172 and 946 placentas that were entered into the study at Lancet and NHLS, respectively. MVM was the most prevalent pathology seen in both laboratories (40.6% and 47.7%; p =0.3193). Mean maternal and gestational age were both higher in the private system (both p <0.0000).  Conclusion. Differences in placental pathology were multifactorial and reasons may include differences in socioeconomic status and resources, clinical and laboratory policies and practices, as well as pathologist training and expertise. Clear clinical guidelines for the submission and histopathological examination of the placenta are required to better inform neonatal and maternal healthcare and policies. In our divided healthcare system, collaborative medical research is not only possible between the public and private sectors but also necessary to achieve better healthcare and equity for patients in South Africa.
背景实验室信息系统拥有丰富的患者和健康数据,可用于研究。这些数据可以更好地为医疗服务的提供和政策的制定提供信息。胎盘只是一个组织病理学实验室标本,可以提供这样的见解,特别是在孕产妇和新生儿保健方面。目标。描述私人和公共实验室中胎盘病理学的范围,并确定对改善孕产妇和新生儿保健和政策的影响。方法。我们对约翰内斯堡柳叶刀实验室和国家卫生实验室(NHLS)在一年内(2017年8月至2018年7月)的胎盘组织病理学报告进行了回顾性描述性研究。根据2014年阿姆斯特丹胎盘工作坊小组共识声明以及两个实验室之间每个诊断实体的百分比对报告进行分类。这些诊断类别包括上行感染、母体血管灌注不良(MVM)、胎儿血管灌注不良、血液源性感染、病因不明的慢性绒毛炎、胎盘后出血、无特定病理变化和“其他”。还比较了产妇年龄和胎龄的差异。结果。Lancet和NHLS分别有1172和946个胎盘参与了这项研究。MVM是两个实验室中最常见的病理学(40.6%和47.7%;p=0.3193)。在私人系统中,平均产妇和胎龄均较高(均p<0.0000)。结论。胎盘病理学的差异是多因素的,原因可能包括社会经济地位和资源、临床和实验室政策和实践以及病理学家培训和专业知识的差异。需要明确的胎盘提交和组织病理学检查的临床指南,以更好地为新生儿和产妇的医疗保健和政策提供信息。在我们分裂的医疗体系中,公共和私营部门之间的合作医疗研究不仅是可能的,而且对于南非实现更好的医疗保健和患者公平也是必要的。
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引用次数: 0
The impact of COVID-19 on obstetrics and gynaecology care COVID-19对妇产科护理的影响
Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2020-12-01 DOI: 10.7196/SAJOG.2020.V26I2.02028
Z. Abdool, S. Maswime, W. Edridge
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引用次数: 0
Mitigating the judicious use of PPE to keep maternity units functional 减少个人防护装备的明智使用,以保持产科单位的功能
Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2020-09-21 DOI: 10.7196/SAJOG.1605
S. Adam, S. Maswime, P. Soma-Pillay, M. Matjila, L. Chauke, M. Botha, R. Pattinson
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引用次数: 0
Contents 内容
Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2020-09-21 DOI: 10.7196/sajog.1626
Gertrude Fani
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引用次数: 0
Solid pseudopapillary tumour of the pancreas in pregnancy – a case report and literature review 妊娠期胰腺实性假乳头状肿瘤一例报告及文献复习
Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2020-09-15 DOI: 10.7196/sajog.1623
TA Motsepe, A. Mokhtari, N. Releni, RF Mahabane, MC Khaba
Solid pseudopapillary pancreatic tumours (SPTs) are tumours with a low malignant potential though they may metastasise. They are rare in pregnancy and their accelerated growth during pregnancy could be life-threatening. The challenge remains as to how best to treat pregnant patients diagnosed with or suspected of having these tumours. We report a case of a 28-year-old pregnant female patient at 20 weeks’ gestation who presented with mild abdominal pain and an abdominal mass. Physical examination showed an asymmetrical abdomen with associated mild tenderness. Radiological imaging showed a right-sided retroperitoneal tumour. Surgical management was deferred until the pregnancy was at full term. At term, once a live baby had been delivered, excision of the mass was performed. Histopathological assessment showed a solid pseudopapillary tumour of the pancreas. A multidisciplinary approach to a pregnant patient diagnosed with SPT is necessary to ensure the best outcome for both mother and child.
胰腺实性假乳头状肿瘤(SPTs)是一种恶性潜能较低的肿瘤,尽管它们可能会转移。它们在怀孕期间很罕见,在怀孕期间加速生长可能会危及生命。如何最好地治疗被诊断患有或疑似患有这些肿瘤的孕妇仍然是一个挑战。我们报告一例28岁怀孕20周的女性患者,她表现为轻度腹痛和腹部肿块。体检显示腹部不对称,伴有轻度压痛。影像学检查显示右侧腹膜后肿瘤。手术治疗被推迟到足月。足月时,一旦生下活婴儿,就要切除肿块。组织病理学评估显示胰腺实性假乳头状肿瘤。对诊断为SPT的孕妇采取多学科方法是必要的,以确保母亲和孩子都能获得最佳结果。
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引用次数: 0
Cover 封面
Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2020-09-15 DOI: 10.7196/sajog.1627
Gertrude Fani
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引用次数: 0
期刊
South African Journal of Obstetrics and Gynaecology
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