Pub Date : 2026-01-30DOI: 10.1186/s13014-026-02792-2
Ellen Heurlin, Vitali Grozman, Suzanne Egyhazi Brage, Karin Lindberg, Hildur Helgadottir
{"title":"Stereotactic body radiation therapy for oligometastatic melanoma: a real-world study of the ESTRO/EORTC nomenclature.","authors":"Ellen Heurlin, Vitali Grozman, Suzanne Egyhazi Brage, Karin Lindberg, Hildur Helgadottir","doi":"10.1186/s13014-026-02792-2","DOIUrl":"https://doi.org/10.1186/s13014-026-02792-2","url":null,"abstract":"","PeriodicalId":49639,"journal":{"name":"Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146087723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-22DOI: 10.1186/s13014-025-02768-8
G Sinclair, H Martin, C M Allison, M A Hatiboglu, H Speckter, A Fytagoridis
{"title":"Correction: Management of critically located brain metastases in patients with precluded survival using customised double-dose prescription-based, adaptive accelerated staged radiosurgery: a long-term retrospective analysis.","authors":"G Sinclair, H Martin, C M Allison, M A Hatiboglu, H Speckter, A Fytagoridis","doi":"10.1186/s13014-025-02768-8","DOIUrl":"10.1186/s13014-025-02768-8","url":null,"abstract":"","PeriodicalId":49639,"journal":{"name":"Radiation Oncology","volume":"21 1","pages":"16"},"PeriodicalIF":3.3,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12825261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146031481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-16DOI: 10.1186/s13014-026-02789-x
Adams Hei Long Yuen, Matthew Shing Cheung Yik, Kenneth Tsz Hei Chung, Fuk Hay Tang, Christopher Wai Keung Lai, Yue Li, Yaqing Nong, Mingmei Tang, Zhen Zhang, Xingliu Wang, Xiaoshen Wang, Weihua Zhu, Fuqiang Chen, Alex Hoi Ning Leung, Jacky Tsz Lung Wong
{"title":"Integrating static angle ports and dynamic collimator rotation in volumetric modulated arc therapy for hypofractionated whole breast irradiation in Chinese females: a single-centre dosimetric study.","authors":"Adams Hei Long Yuen, Matthew Shing Cheung Yik, Kenneth Tsz Hei Chung, Fuk Hay Tang, Christopher Wai Keung Lai, Yue Li, Yaqing Nong, Mingmei Tang, Zhen Zhang, Xingliu Wang, Xiaoshen Wang, Weihua Zhu, Fuqiang Chen, Alex Hoi Ning Leung, Jacky Tsz Lung Wong","doi":"10.1186/s13014-026-02789-x","DOIUrl":"10.1186/s13014-026-02789-x","url":null,"abstract":"","PeriodicalId":49639,"journal":{"name":"Radiation Oncology","volume":" ","pages":"25"},"PeriodicalIF":3.3,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12874935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145991554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-12DOI: 10.1186/s13014-025-02735-3
Jon Gadea-Quinteiro, Francisco Mestre, Marc Alomar, Ignacio González-Alcantud, Samuel Torres-García, Carlos García-Zanoguera, Antonia Perelló, Pau Camarasa, Gabriel Matheu, Miriam Sansó, Octavi Córdoba
{"title":"Definitive single-fraction ablative radiotherapy for early-stage breast cancer: DESERT-I trial - a dose-escalation study protocol.","authors":"Jon Gadea-Quinteiro, Francisco Mestre, Marc Alomar, Ignacio González-Alcantud, Samuel Torres-García, Carlos García-Zanoguera, Antonia Perelló, Pau Camarasa, Gabriel Matheu, Miriam Sansó, Octavi Córdoba","doi":"10.1186/s13014-025-02735-3","DOIUrl":"10.1186/s13014-025-02735-3","url":null,"abstract":"","PeriodicalId":49639,"journal":{"name":"Radiation Oncology","volume":"21 1","pages":"9"},"PeriodicalIF":3.3,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12794304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145953772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Surgery is the primary therapy for hard palate cancer, but this sometime worsens oral function and unavailable for patients with several comorbidities. Radiotherapy represents an alternative curative treatment option to preserve oral function, however, there are few reports on the use of radiotherapy for squamous cell carcinoma of the hard palate (SCCHP). High-dose-rate (HDR) brachytherapy has been known as an effective treatment for SCCHP, which seems to be less invasive when mold technique is used. In our hospital, the HDR customized mold brachytherapy (HDR- customized MBT) is available for patients with SCCHP. This study aimed to report the efficacy and toxicity of HDR- customized MBT for patients with early-stage SCCHP.
Case presentation: Four patients with early-stage SCCHP were treated with mainly HDR- customized MBT between June 2015 and May 2023. Three of four patients received the combined radiotherapy: one patient underwent short-term external beam radiotherapy (EBRT) before the HDR- customized MBT; two patients underwent single-fraction interstitial brachytherapy before HDR- customized MBT. The total biological effective dose was 77-110 Gy (α/β = 10). All patients completed HDR- customized MBT with or without the combined radiotherapy and experienced no local recurrence. The acute toxicity was only mucositis limited to the irradiated area: one case with EBRT developed grade 2 mucositis. Only this case had late grade 2 mucositis; no late adverse events were observed in the other cases. No oral dysfunction or cosmetic problems occurred in any of the patients.
Conclusions: This study might show that HDR-customized MBT is useful for early-stage SCCHP and might be an alternative curative treatment option for them to preserve oral function.
{"title":"Case reports that high-dose-rate brachytherapy using custom-designed mouthpiece mold for early-stage squamous cell carcinoma of the hard palate is useful.","authors":"Yuki Yoshino, Koji Masui, Tadashi Takenaka, Kanako Kawabata, Norihiro Aibe, Takuya Kimoto, Shinsuke Nagasawa, Tomohiro Kajikawa, Satoshi Ikeda, Tadahiro Kawamoto, Fumishige Oseko, Hideya Yamazaki, Kei Yamada, Gen Suzuki","doi":"10.1186/s13014-025-02775-9","DOIUrl":"10.1186/s13014-025-02775-9","url":null,"abstract":"<p><strong>Background: </strong>Surgery is the primary therapy for hard palate cancer, but this sometime worsens oral function and unavailable for patients with several comorbidities. Radiotherapy represents an alternative curative treatment option to preserve oral function, however, there are few reports on the use of radiotherapy for squamous cell carcinoma of the hard palate (SCCHP). High-dose-rate (HDR) brachytherapy has been known as an effective treatment for SCCHP, which seems to be less invasive when mold technique is used. In our hospital, the HDR customized mold brachytherapy (HDR- customized MBT) is available for patients with SCCHP. This study aimed to report the efficacy and toxicity of HDR- customized MBT for patients with early-stage SCCHP.</p><p><strong>Case presentation: </strong>Four patients with early-stage SCCHP were treated with mainly HDR- customized MBT between June 2015 and May 2023. Three of four patients received the combined radiotherapy: one patient underwent short-term external beam radiotherapy (EBRT) before the HDR- customized MBT; two patients underwent single-fraction interstitial brachytherapy before HDR- customized MBT. The total biological effective dose was 77-110 Gy (α/β = 10). All patients completed HDR- customized MBT with or without the combined radiotherapy and experienced no local recurrence. The acute toxicity was only mucositis limited to the irradiated area: one case with EBRT developed grade 2 mucositis. Only this case had late grade 2 mucositis; no late adverse events were observed in the other cases. No oral dysfunction or cosmetic problems occurred in any of the patients.</p><p><strong>Conclusions: </strong>This study might show that HDR-customized MBT is useful for early-stage SCCHP and might be an alternative curative treatment option for them to preserve oral function.</p>","PeriodicalId":49639,"journal":{"name":"Radiation Oncology","volume":" ","pages":"27"},"PeriodicalIF":3.3,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12874970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145960506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-10DOI: 10.1186/s13014-026-02787-z
Andrew B Bonner, Herbert Chen, Sharon A Spencer, Christopher D Willey, Adam J Kole
{"title":"The effect of timing of post-operative radiation on outcomes in anaplastic thyroid cancer.","authors":"Andrew B Bonner, Herbert Chen, Sharon A Spencer, Christopher D Willey, Adam J Kole","doi":"10.1186/s13014-026-02787-z","DOIUrl":"10.1186/s13014-026-02787-z","url":null,"abstract":"","PeriodicalId":49639,"journal":{"name":"Radiation Oncology","volume":" ","pages":"28"},"PeriodicalIF":3.3,"publicationDate":"2026-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12905978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145949359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1186/s13014-025-02729-1
Marinka J Remmelink, Nader El Awadly, Berber Arbeel-Weening, Sven Nadorp, Maicle R Leter, Jorg R Oddens, Katharina Brück, Jakko A Nieuwenhuijzen, Adriaan D Bins
{"title":"Correction: Impact of chemoradiotherapy for bladder cancer on pre-existing hydronephrosis and development of new hydronephrosis.","authors":"Marinka J Remmelink, Nader El Awadly, Berber Arbeel-Weening, Sven Nadorp, Maicle R Leter, Jorg R Oddens, Katharina Brück, Jakko A Nieuwenhuijzen, Adriaan D Bins","doi":"10.1186/s13014-025-02729-1","DOIUrl":"10.1186/s13014-025-02729-1","url":null,"abstract":"","PeriodicalId":49639,"journal":{"name":"Radiation Oncology","volume":"21 1","pages":"8"},"PeriodicalIF":3.3,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12784547/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145935872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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