{"title":"Progress of the Development of Hypoxia Inducible Factor-1 Small Molecule Inhibitors as Antitumor Agents*","authors":"Xinyu Wang, F-L Zhao, Ru Zhang, Shengnan Liu, Q. Gao","doi":"10.7536/PC201141","DOIUrl":"https://doi.org/10.7536/PC201141","url":null,"abstract":"","PeriodicalId":49662,"journal":{"name":"Progress in Chemistry","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2021-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85414683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guanyi Chen, Kexuan Han, Caixia Liu, Zeng Dan, B. Duo
{"title":"Removing Heavy Metals from Sludge","authors":"Guanyi Chen, Kexuan Han, Caixia Liu, Zeng Dan, B. Duo","doi":"10.7536/PC200731","DOIUrl":"https://doi.org/10.7536/PC200731","url":null,"abstract":"","PeriodicalId":49662,"journal":{"name":"Progress in Chemistry","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2021-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73899171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In-Situ Polymerization Electrolytes for Lithium Rechargeable Batteries","authors":"Wentao Li, Hai Zhong, Y. Mai","doi":"10.7536/PC200733","DOIUrl":"https://doi.org/10.7536/PC200733","url":null,"abstract":"","PeriodicalId":49662,"journal":{"name":"Progress in Chemistry","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2021-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88538431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xuefen Tao, Ji‐pan Yu, L. Mei, Chang‐ming Nie, Z. Chai, W. Shi
{"title":"Dinitrogen Activation by Uranium Complex","authors":"Xuefen Tao, Ji‐pan Yu, L. Mei, Chang‐ming Nie, Z. Chai, W. Shi","doi":"10.7536/PC200671","DOIUrl":"https://doi.org/10.7536/PC200671","url":null,"abstract":"","PeriodicalId":49662,"journal":{"name":"Progress in Chemistry","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2021-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74047797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pt-Based Electrocatalysts with Special Three-Dimensional Morphology or Nanostructure","authors":"Xiang‐Ling Tang, Jiaxiang Chen, Lina Liu, Shijun Liao","doi":"10.7536/PC210218","DOIUrl":"https://doi.org/10.7536/PC210218","url":null,"abstract":"","PeriodicalId":49662,"journal":{"name":"Progress in Chemistry","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2021-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76902607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tang Xiang-chun, Chen Jia-xiang, Liu Li-na, Liao Shi-jun
{"title":"Research Progress on the Pt-based Electrocatalysts with Special Three-dimensional Morphology or Nanostructure","authors":"Tang Xiang-chun, Chen Jia-xiang, Liu Li-na, Liao Shi-jun","doi":"10.7536/PC200218","DOIUrl":"https://doi.org/10.7536/PC200218","url":null,"abstract":"","PeriodicalId":49662,"journal":{"name":"Progress in Chemistry","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2021-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85071666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-22DOI: 10.35799/cp.14.1.2021.34128
Gladys K Bungan, Henry F. Aritonang, Audy D. Wuntu
Penelitian tentang pembuatan nanokomposit kitosan/TiO2/Ag telah dilakukan dengan menggunakan TiO2sebanyak6 gram dan konsentrasi AgNO3 yaitu 5 mM menggunakan metode reduksi dan impregnasi. Nanokomposit yang dihasilkan dikarakterisasi menggunakan X-Ray diffractometry (XRD), Scanning Electron Microscope-Energy Dispersive x-Ray Spectroscopy (SEM-EDS) dan menganalisis aktivitasnya sebagai anti bakteri terhadap Staphylococcus aureus (Gram positif) dan Escherichia coli (gram negatif). Hasil penelitian menunjukkan bahwa ukuran nanokomposit yang dihasilkan sebesar 56,93 nm. Difraktogram XRD muncul puncak karakteristik partikel TiO2 tetapi partikel Ag kurang terlihat jelas. Namun, berdasarkan data EDS, kedua partikel ini ditemukan pada membran kitosan. Ini menunjukkan bahwa sangat sedikit partikel Ag yang terbentuk atau keterbatasan alat XRD dalam mendeteksi sejumlah kecil partikel. Namun demikian, nanokomposit menunjukkan kemampuannya untuk menghambat pertumbuhan kedua bakteri ini.ABSTRACTResearch on the manufacture of chitosan/TiO2/Ag nanocomposites has been carried out using 6 grams of TiO2 and 5 mM AgNO3 using reduction and impregnation methods.The resulting nanocomposites were characterized using X-Ray diffraction (XRD), Scanning Electron Microscope-Energy Dispersive x-Ray Spectroscopy (SEM-EDS) and analyzed their activity as anti-bacteria against Staphylococcus aureus (Gram positive) and Escherichia coli (gram negative).The results showed that the resulting nanocomposite size was 56.93 nm. The XRD diffractogram showed the peak characteristics of TiO2 particles but the Ag particles were less visible.However, based on EDS data, the two particles were found on the chitosan membrane. This indicates that very few Ag particles are formed or the limitations of XRD devices in detecting a small number of Ag particles.However, the nanocomposites demonstrated their ability to inhibit the growth of these two bacteria.
{"title":"PEMBUATAN NANOKOMPOSIT KITOSAN/TiO2/Ag DAN ANALISIS AKTIVITASNYA SEBAGAI ANTIBAKTERI","authors":"Gladys K Bungan, Henry F. Aritonang, Audy D. Wuntu","doi":"10.35799/cp.14.1.2021.34128","DOIUrl":"https://doi.org/10.35799/cp.14.1.2021.34128","url":null,"abstract":"Penelitian tentang pembuatan nanokomposit kitosan/TiO2/Ag telah dilakukan dengan menggunakan TiO2sebanyak6 gram dan konsentrasi AgNO3 yaitu 5 mM menggunakan metode reduksi dan impregnasi. Nanokomposit yang dihasilkan dikarakterisasi menggunakan X-Ray diffractometry (XRD), Scanning Electron Microscope-Energy Dispersive x-Ray Spectroscopy (SEM-EDS) dan menganalisis aktivitasnya sebagai anti bakteri terhadap Staphylococcus aureus (Gram positif) dan Escherichia coli (gram negatif). Hasil penelitian menunjukkan bahwa ukuran nanokomposit yang dihasilkan sebesar 56,93 nm. Difraktogram XRD muncul puncak karakteristik partikel TiO2 tetapi partikel Ag kurang terlihat jelas. Namun, berdasarkan data EDS, kedua partikel ini ditemukan pada membran kitosan. Ini menunjukkan bahwa sangat sedikit partikel Ag yang terbentuk atau keterbatasan alat XRD dalam mendeteksi sejumlah kecil partikel. Namun demikian, nanokomposit menunjukkan kemampuannya untuk menghambat pertumbuhan kedua bakteri ini.ABSTRACTResearch on the manufacture of chitosan/TiO2/Ag nanocomposites has been carried out using 6 grams of TiO2 and 5 mM AgNO3 using reduction and impregnation methods.The resulting nanocomposites were characterized using X-Ray diffraction (XRD), Scanning Electron Microscope-Energy Dispersive x-Ray Spectroscopy (SEM-EDS) and analyzed their activity as anti-bacteria against Staphylococcus aureus (Gram positive) and Escherichia coli (gram negative).The results showed that the resulting nanocomposite size was 56.93 nm. The XRD diffractogram showed the peak characteristics of TiO2 particles but the Ag particles were less visible.However, based on EDS data, the two particles were found on the chitosan membrane. This indicates that very few Ag particles are formed or the limitations of XRD devices in detecting a small number of Ag particles.However, the nanocomposites demonstrated their ability to inhibit the growth of these two bacteria.","PeriodicalId":49662,"journal":{"name":"Progress in Chemistry","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2021-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79199513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-22DOI: 10.35799/cp.14.1.2021.34129
Oki Oktaviani Dika, E. Suryanto, L. Momuat
Tujuan dari penelitian ini untuk mengekstraksi dan mengkarakterisasi antioksidan serat pangan dari kulit lemon cui (Citrus microcarpa) dengan perbedaan pelarut menggunakan gelombang ultrasonik. Hasil penelitian menunjukkan bahwa tepung kulit lemon cui yang diekstraksi dengan perbedaan pelarut tidak mengalami perubahan mendasar pada komponen utama ditunjukkan pada hasil spectra Fourier Transfrom Infra Red (FT-IR). Karakterisasi secara kimia menunjukkan TPKLC memiliki kandungan air (8,49%), abu (4,44%), lemak (0,8%), protein (12,45%), dan karbohidrat (73,99%). AKLC mengandung air (1,71%), abu (4,41%), lemak (0,56%), protein (10,56%), karbohidrat (82,76%). EKLC mengandung air (7,88%), abu (6,18%), lemak (1,04%), protein (7,68%), karbohidrat (77,22%). Hasil pengujian aktivitas antioksidan menunjukkan bahwa ekstrak fenolik EKLC (96,48%) tertinggi diikuti oleh ekstrak fenolik AKLC (95,45%), dan ekstrak fenolik TPKLC (94,29%).Hasil penelitian ini menunjukkan bahwa dengan pelarut etanol dapat meningkatkan aktivitas antioksidan dibanding dengan pelarut aquades.ABSTRACTObjective of this study to extract and characterize antioxidant dietary fiber from lemon peel cui (Citrusmicrocarpa)with different solvents using wave ultrasonic. The results showed that the lemon cui peel powder extracted with different solvents did not experience a fundamental change in the main component as shown in the results of the Fourier Transfrom Infra Red (FT-IR) spectra. Chemical characterization showed that TPKLC contained water (8.49%), ash (4.44%), fat (0.8%), protein (12.45%), and carbohydrates (73.99%). AKLC contains water (1.71%), ash (4.41%), fat (0.56%), protein (10.56%), carbohydrates (82.76%). EKLC contains water (7.88%), ash (6.18%), fat (1.04%), protein (7.68%), carbohydrates (77.22%). The results of the antioxidant activity test showed that the highest EKLC phenolic extract (96.48%) was followed by AKLC phenolic extract (95.45%), and TPKLC phenolic extract (94.29%). The results of this study indicate that ethanol solvent can increase antioxidant activity compared to distilled water solvent.
{"title":"KARAKTERISASI DAN AKTIVITAS ANTIOKSIDAN SERAT PANGAN DARI TEPUNG KULIT LEMON CUI (Citrus microcarpa)","authors":"Oki Oktaviani Dika, E. Suryanto, L. Momuat","doi":"10.35799/cp.14.1.2021.34129","DOIUrl":"https://doi.org/10.35799/cp.14.1.2021.34129","url":null,"abstract":"Tujuan dari penelitian ini untuk mengekstraksi dan mengkarakterisasi antioksidan serat pangan dari kulit lemon cui (Citrus microcarpa) dengan perbedaan pelarut menggunakan gelombang ultrasonik. Hasil penelitian menunjukkan bahwa tepung kulit lemon cui yang diekstraksi dengan perbedaan pelarut tidak mengalami perubahan mendasar pada komponen utama ditunjukkan pada hasil spectra Fourier Transfrom Infra Red (FT-IR). Karakterisasi secara kimia menunjukkan TPKLC memiliki kandungan air (8,49%), abu (4,44%), lemak (0,8%), protein (12,45%), dan karbohidrat (73,99%). AKLC mengandung air (1,71%), abu (4,41%), lemak (0,56%), protein (10,56%), karbohidrat (82,76%). EKLC mengandung air (7,88%), abu (6,18%), lemak (1,04%), protein (7,68%), karbohidrat (77,22%). Hasil pengujian aktivitas antioksidan menunjukkan bahwa ekstrak fenolik EKLC (96,48%) tertinggi diikuti oleh ekstrak fenolik AKLC (95,45%), dan ekstrak fenolik TPKLC (94,29%).Hasil penelitian ini menunjukkan bahwa dengan pelarut etanol dapat meningkatkan aktivitas antioksidan dibanding dengan pelarut aquades.ABSTRACTObjective of this study to extract and characterize antioxidant dietary fiber from lemon peel cui (Citrusmicrocarpa)with different solvents using wave ultrasonic. The results showed that the lemon cui peel powder extracted with different solvents did not experience a fundamental change in the main component as shown in the results of the Fourier Transfrom Infra Red (FT-IR) spectra. Chemical characterization showed that TPKLC contained water (8.49%), ash (4.44%), fat (0.8%), protein (12.45%), and carbohydrates (73.99%). AKLC contains water (1.71%), ash (4.41%), fat (0.56%), protein (10.56%), carbohydrates (82.76%). EKLC contains water (7.88%), ash (6.18%), fat (1.04%), protein (7.68%), carbohydrates (77.22%). The results of the antioxidant activity test showed that the highest EKLC phenolic extract (96.48%) was followed by AKLC phenolic extract (95.45%), and TPKLC phenolic extract (94.29%). The results of this study indicate that ethanol solvent can increase antioxidant activity compared to distilled water solvent.","PeriodicalId":49662,"journal":{"name":"Progress in Chemistry","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2021-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79618617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}