Mario Kasović, L. Štefan, Marrtin Zvonař, Alena Cepková, P. Šagát, P. Bartík
The main purpose of the present study was to develop smoothed percentile curves for physical fitness in adolescents aged 15-18 years from the City of Zagreb. In this cross-sectional study, we recruited 1036 secondary-school students aged 15-18 from eleven randomly selected schools (55.3% of girls). As part of physical fitness, we chose 1-minute sit-ups (#), standing long jump (cm) and sit-and-reach (cm) tests using standardized measuring protocol. The sex- and age-specific smoothed percentile curves with 5th, 10th, 25th, 50th, 75th, 90th and 95th percentile for each physical fitness test were calculated using Lambda-Mu-Sigma method. The 50th percentile for 1-minute sit-ups was between 55 and 58 cm in boys, and between 45 and 47.5 cm in girls. For standing long jump, 50th percentile was between 210 and 215 cm in boys and roughly the same (170 cm) in girls. Finally, 50th percentile for sit-and-reach test was between 60 and 65 cm in boys and between 67.5 and 73 cm in girls. This study aimed to establish physical fitness percentile curves for adolescents from the City of Zagreb. Our reference curves might be used to detect adolescents who are at an extreme risk of having 'low' physical fitness status and to implement school-based interventions for physical fitness level enhancement.
{"title":"Establishing sex-and age-specific percentile curves for some aspects of physical fitness in adolescents from the City of Zagreb","authors":"Mario Kasović, L. Štefan, Marrtin Zvonař, Alena Cepková, P. Šagát, P. Bartík","doi":"10.13112/PC.2020.4","DOIUrl":"https://doi.org/10.13112/PC.2020.4","url":null,"abstract":"The main purpose of the present study was to develop smoothed percentile curves for physical fitness in adolescents aged 15-18 years from the City of Zagreb. In this cross-sectional study, we recruited 1036 secondary-school students aged 15-18 from eleven randomly selected schools (55.3% of girls). As part of physical fitness, we chose 1-minute sit-ups (#), standing long jump (cm) and sit-and-reach (cm) tests using standardized measuring protocol. The sex- and age-specific smoothed percentile curves with 5th, 10th, 25th, 50th, 75th, 90th and 95th percentile for each physical fitness test were calculated using Lambda-Mu-Sigma method. The 50th percentile for 1-minute sit-ups was between 55 and 58 cm in boys, and between 45 and 47.5 cm in girls. For standing long jump, 50th percentile was between 210 and 215 cm in boys and roughly the same (170 cm) in girls. Finally, 50th percentile for sit-and-reach test was between 60 and 65 cm in boys and between 67.5 and 73 cm in girls. This study aimed to establish physical fitness percentile curves for adolescents from the City of Zagreb. Our reference curves might be used to detect adolescents who are at an extreme risk of having 'low' physical fitness status and to implement school-based interventions for physical fitness level enhancement.","PeriodicalId":49715,"journal":{"name":"Paediatria Croatica","volume":"64 1","pages":"21-26"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42863499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tatjana Čulina, Sandra Anđelić Breš, Sandro Kresina, Maja Sepčić
{"title":"Stavovi roditelja o cijepljenju u nekoliko škola PGŽ-a","authors":"Tatjana Čulina, Sandra Anđelić Breš, Sandro Kresina, Maja Sepčić","doi":"10.13112/PC.2018.4","DOIUrl":"https://doi.org/10.13112/PC.2018.4","url":null,"abstract":"","PeriodicalId":49715,"journal":{"name":"Paediatria Croatica","volume":"62 1","pages":"20-24"},"PeriodicalIF":0.0,"publicationDate":"2020-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.13112/PC.2018.4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44207923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Ilić, T. Ištvanić, Darja Sokolić, Irena Keser, Dragica Šakić, T. Niseteo, Irena Colić Barić, Ivana Rumbak
Cilj ovog rada je utvrditi unos ukupnih proteina u male djece i proteina s obzirom na podrijetlo te identificirati njihove glavne izvore u ranom djetinjstvu. Cilj je također utvrditi postoji li razlika u unosu proteina s obzirom na demografske i antropometrijske karakte ristike te socioekonomski status ispitanika. U istraživanju je sudjelovalo 130ero male djece (49,2% djevojčica i 50,8% dječaka) prosječne dobi od 23,5 ± 0,7 mjeseci. Podatci o ispitanicima su se prikupljali općim upitnikom i dnevnikom prehrane što su ga dva neuzastopna dana vodili roditelji. Djeca unose 3,5 ± 0,1 g/kgTM proteina na dan, a to znači više od preporuka. Pritom unose više proteina životinjskog (2,3 ± 0,1 g/kgTM) podrijetla nego biljnog (1,2 ± 0,05 g/kgTM). Skupina namirnica od mesa, peradi, ribe i jaja (32,1%) pridonosi najvećem unosu proteina, potom od mlijeka i mliječnih proizvoda (28,1%) te skupina s krumpirom i žitaricama (15,7%). Razlika u unosu proteina te omjer onih životinjskih naprama biljnih s obzirom na spol, indeks djetetove tjelesne mase, traja nje isključivog dojenja te dobi u trenutku početka dohrane nije se pokazala statistički značajnom. S obzirom na socioekonomski status analizom podataka je zamijećeno da porastom socioekonomskog statusa djeca konzumiraju značajno više (p=0,012) biljnih proteina (1,1 ± 0,1 g/kgTM, 1,2 ± 0,1 g/kgTM, 1,6 ± 0,1 g/kgTM). Unos proteina u ovom uzorku male djece s područja Hrvatske više struko premašuje važeće preporuke. Unos životinjskih proteina dvostruko je veći od unosa biljnih, što je posebice izraženo u obitelji ma nižeg socioekonomskog statusa.
这项工作的目的是建立将总蛋白质引入幼儿和基于来源的蛋白质，并确定其在幼儿期的主要来源。目的还在于确定蛋白质输入是否因受试者的人口统计学和人体测量特征以及社会经济地位而存在差异。U istraživanju je sudjelovalo 130名男性djece（49.2%djevojčica i 50.8%dječaka）prosječne dobi od 23.5±0.7 mjeseci。受试者的数据是通过一般问卷和饮食日记收集的，父母在两天内毫不拖延地进行了饮食日记。儿童每天摄入3.5±0.1 g/kgTM蛋白质，这意味着超过了建议。当引入更多的动物蛋白（2.3±0.1g/kgTM）时，其来源于植物蛋白（1.2±0.05g/kgTM。一组肉、佩拉迪、鱼和蛋（32.1%）的蛋白质输入量最高，其次是牛奶和乳制品（28.1%）以及一组土豆和谷物（15.7%）。在给定性别、体重指数、纯母乳喂养持续时间和开始进食时的年龄的情况下，蛋白质输入和植物产品比例的差异没有统计学意义。根据社会经济地位分析，观察到数据显著增加了儿童的社会经济地位（p=0.012）植物蛋白（1.1±0.1 g/kgTM、1.2±0.1 g/kg TM、1.6±0.1 g/kg-TM）。在克罗地亚幼儿样本中引入的蛋白质超过了重要建议。动物蛋白质是草药投入的两倍，尤其是在社会经济地位较低的家庭中。
{"title":"Unos proteina u male djece: izvori iz hrane i čimbenici vezani za način života","authors":"A. Ilić, T. Ištvanić, Darja Sokolić, Irena Keser, Dragica Šakić, T. Niseteo, Irena Colić Barić, Ivana Rumbak","doi":"10.13112/PC.2020.26","DOIUrl":"https://doi.org/10.13112/PC.2020.26","url":null,"abstract":"Cilj ovog rada je utvrditi unos ukupnih proteina u male djece i proteina s obzirom na podrijetlo te identificirati njihove glavne izvore u ranom djetinjstvu. Cilj je također utvrditi postoji li razlika u unosu proteina s obzirom na demografske i antropometrijske karakte ristike te socioekonomski status ispitanika. U istraživanju je sudjelovalo 130ero male djece (49,2% djevojčica i 50,8% dječaka) prosječne dobi od 23,5 ± 0,7 mjeseci. Podatci o ispitanicima su se prikupljali općim upitnikom i dnevnikom prehrane što su ga dva neuzastopna dana vodili roditelji. Djeca unose 3,5 ± 0,1 g/kgTM proteina na dan, a to znači više od preporuka. Pritom unose više proteina životinjskog (2,3 ± 0,1 g/kgTM) podrijetla nego biljnog (1,2 ± 0,05 g/kgTM). Skupina namirnica od mesa, peradi, ribe i jaja (32,1%) pridonosi najvećem unosu proteina, potom od mlijeka i mliječnih proizvoda (28,1%) te skupina s krumpirom i žitaricama (15,7%). Razlika u unosu proteina te omjer onih životinjskih naprama biljnih s obzirom na spol, indeks djetetove tjelesne mase, traja nje isključivog dojenja te dobi u trenutku početka dohrane nije se pokazala statistički značajnom. S obzirom na socioekonomski status analizom podataka je zamijećeno da porastom socioekonomskog statusa djeca konzumiraju značajno više (p=0,012) biljnih proteina (1,1 ± 0,1 g/kgTM, 1,2 ± 0,1 g/kgTM, 1,6 ± 0,1 g/kgTM). Unos proteina u ovom uzorku male djece s područja Hrvatske više struko premašuje važeće preporuke. Unos životinjskih proteina dvostruko je veći od unosa biljnih, što je posebice izraženo u obitelji ma nižeg socioekonomskog statusa.","PeriodicalId":49715,"journal":{"name":"Paediatria Croatica","volume":"64 1","pages":"166-173"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66774104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ulaganja u djecu kao visoko isplativa socijalna investicija","authors":"Zdenko Babić","doi":"10.13112/PC.2020.9","DOIUrl":"https://doi.org/10.13112/PC.2020.9","url":null,"abstract":"","PeriodicalId":49715,"journal":{"name":"Paediatria Croatica","volume":"64 1","pages":"56-64"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66774398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neuronal ceroid lipofuscinosis type 2 (CLN2) is the most common childhood progressive neurodegenerative disease. The main features of CLN2 disease are language delay that precedes epileptic seizures, motor disorders, progressive deterioration of vision and cognition with death in early adolescence. The average time from the onset of fi rst symptoms to diagnosis is about two years. Delay in diagnosis postpones therapeutic approach involving multidisciplinary health care and effi cacious enzyme replacement therapy with cerliponase alpha (Brineura®). The availability of enzyme replacement therapy classifi es CLN2 disease in the group of treatable neurodegenerative diseases. Recognition of early symptoms is crucial to direct clinicians to appropriate examinations or seek additional expert opinion. Timely diagnosis is imperative because it allows treatment at an early stage of the disease. In all children with the fi rst unprovoked epileptic seizures between the ages of two and four, and particularly in those children with a history of language delay and motor impairment, the fi rst step is to measure the TTP1 enzyme activity by dried blood spot testing, which is available in our setting. Genetic testing and a fi nding of pathogenic mutations in the CLN2 gene confi rm the diagnosis. Raising awareness of CLN2 disease as a treatable and potentially curable disease and following the proposed guidelines will certainly contribute to early diagnosis of CLN2 disease to become our reality rather than a myth. Timely and accurate diagnosis is the fi rst step in improving the overall care of children with CLN2 disease and their parents.
{"title":"Early diagnosis of neuronal ceroid lipofuscinosis type 2 – a myth or reality?","authors":"I. Prpić","doi":"10.13112/PC.2020.34","DOIUrl":"https://doi.org/10.13112/PC.2020.34","url":null,"abstract":"Neuronal ceroid lipofuscinosis type 2 (CLN2) is the most common childhood progressive neurodegenerative disease. The main features of CLN2 disease are language delay that precedes epileptic seizures, motor disorders, progressive deterioration of vision and cognition with death in early adolescence. The average time from the onset of fi rst symptoms to diagnosis is about two years. Delay in diagnosis postpones therapeutic approach involving multidisciplinary health care and effi cacious enzyme replacement therapy with cerliponase alpha (Brineura®). The availability of enzyme replacement therapy classifi es CLN2 disease in the group of treatable neurodegenerative diseases. Recognition of early symptoms is crucial to direct clinicians to appropriate examinations or seek additional expert opinion. Timely diagnosis is imperative because it allows treatment at an early stage of the disease. In all children with the fi rst unprovoked epileptic seizures between the ages of two and four, and particularly in those children with a history of language delay and motor impairment, the fi rst step is to measure the TTP1 enzyme activity by dried blood spot testing, which is available in our setting. Genetic testing and a fi nding of pathogenic mutations in the CLN2 gene confi rm the diagnosis. Raising awareness of CLN2 disease as a treatable and potentially curable disease and following the proposed guidelines will certainly contribute to early diagnosis of CLN2 disease to become our reality rather than a myth. Timely and accurate diagnosis is the fi rst step in improving the overall care of children with CLN2 disease and their parents.","PeriodicalId":49715,"journal":{"name":"Paediatria Croatica","volume":"64 1","pages":"223-228"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66774675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. G. Juraški, M. Turkalj, D. Plavec, B. Nogalo, Ivana Marušić, Marija Miloš, S. Anzić, M. K. Šižgorić, F. Stipoljev
The aim of the study was to assess sleep architecture and breathing in sleep in children with Down syndrome. The study was conducted by using overnight video-polysomnography (V-PSG) in children with Down syndrome and age-matched children from the general population. Analysis of polysomnographic parameters revealed that compared to the norms of healthy ageand maturitymatched children from the general population, children with Down syndrome had significantly shorter sleep latency (p=0.007), shorter total sleep time (p=0.004), lower sleep efficiency (p=0.010), less NREM1 sleep phase (p=0.0002), less NREM3 sleep phase (p=0.034), less REM sleep (p=0.034) in favour of more NREM2 phase but not significantly (p=0.069), and spent more time awake after sleep onset (p=0.0002). Children with Down syndrome had significantly more obstructive sleep apnoeas and hypopnoeas per hour (higher obstructive sleep apnoeas and hypopnoeas index) (p=0.008), but less central sleep apnoea per hour (lower central apnoeas index) (p=0.041), which led to the nonsignificantly lower total apnoea-hypopnoea index (p=0.762) in children with Down syndrome. The mean and longest apnoea duration did not differ significantly between these two groups. Children with Down syndrome had a significantly lower mean and nadir oxygen saturation (p=0.008 and p=0.001, respectively). In conclusion, the majority of respiratory complications in children with Down syndrome can be prevented by raising awareness of sleep disturbances in children with Down syndrome among their parents and health care providers and by introducing early routine V-PSG in the follow up of these children.
{"title":"Sleep phenotype in children with Down syndrome – altered sleep architecture and sleep-disordered breathing","authors":"R. G. Juraški, M. Turkalj, D. Plavec, B. Nogalo, Ivana Marušić, Marija Miloš, S. Anzić, M. K. Šižgorić, F. Stipoljev","doi":"10.13112/pc.2019.37","DOIUrl":"https://doi.org/10.13112/pc.2019.37","url":null,"abstract":"The aim of the study was to assess sleep architecture and breathing in sleep in children with Down syndrome. The study was conducted by using overnight video-polysomnography (V-PSG) in children with Down syndrome and age-matched children from the general population. Analysis of polysomnographic parameters revealed that compared to the norms of healthy ageand maturitymatched children from the general population, children with Down syndrome had significantly shorter sleep latency (p=0.007), shorter total sleep time (p=0.004), lower sleep efficiency (p=0.010), less NREM1 sleep phase (p=0.0002), less NREM3 sleep phase (p=0.034), less REM sleep (p=0.034) in favour of more NREM2 phase but not significantly (p=0.069), and spent more time awake after sleep onset (p=0.0002). Children with Down syndrome had significantly more obstructive sleep apnoeas and hypopnoeas per hour (higher obstructive sleep apnoeas and hypopnoeas index) (p=0.008), but less central sleep apnoea per hour (lower central apnoeas index) (p=0.041), which led to the nonsignificantly lower total apnoea-hypopnoea index (p=0.762) in children with Down syndrome. The mean and longest apnoea duration did not differ significantly between these two groups. Children with Down syndrome had a significantly lower mean and nadir oxygen saturation (p=0.008 and p=0.001, respectively). In conclusion, the majority of respiratory complications in children with Down syndrome can be prevented by raising awareness of sleep disturbances in children with Down syndrome among their parents and health care providers and by introducing early routine V-PSG in the follow up of these children.","PeriodicalId":49715,"journal":{"name":"Paediatria Croatica","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48623734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Kezele, Slaven Medjimurec, Marcel Bukarica, Antonela Čorapović, Ariana Fužinac-Smojver
The aim of this cross sectional study was to assess the quality of life (QOL) and level of physical activity in primary school children with juvenile idiopathic arthritis (JIA) in the Primorje-Gorski Kotar County as compared to healthy peers, and to identify the most pronounced differences in QOL between them. The study included 13 children with JIA recruited from the paediatric rheumatology clinic and 17 healthy children from primary school. The children were aged 8-14 years. All participants, including their parents, completed questionnaires to assess the level of their physical activity (Physical Activity Questionnaire for Children; PAQ-C) and QOL (Pediatric Quality of Life Inventory (PedsQLTM) Generic Core and Rheumatology Module scales). Study results showed statistically significant differences in the QOL associated with physical functioning/health (p=0.033), school activities (p=0.008) and psychosocial health (p=0.033) between JIA and control groups. Responses in the rheumatologic questionnaire revealed a statistically significant difference in the QOL associated with pain (p=0.041), daily activities (p=0.011), treatment (p=0.002), concern (p=0.0006) and communication (p=0.0002) between JIA and control groups. The JIA group showed a significantly lower level of physical activity (p=0.008). There was a statistically significant (p=0.0000) correlation between the QOL associated with pain and the QOL associated with physical functioning/health (r=0.94), emotional functioning (r=0.71), social functioning (r=0.74), school functioning (r=0.56) and psychosocial health (r=0.80). In conclusion, study results suggested JIA to affect QOL in almost all domains in the affected primary school children, with the greatest differences from their healthy peers being recorded in the QOL associated with worrying and communicating about their illness.
{"title":"Quality of life and level of physical activity in primary school children with juvenile idiopathic arthritis in Primorje-Gorski Kotar County","authors":"T. Kezele, Slaven Medjimurec, Marcel Bukarica, Antonela Čorapović, Ariana Fužinac-Smojver","doi":"10.13112/pc.2019.32","DOIUrl":"https://doi.org/10.13112/pc.2019.32","url":null,"abstract":"The aim of this cross sectional study was to assess the quality of life (QOL) and level of physical activity in primary school children with juvenile idiopathic arthritis (JIA) in the Primorje-Gorski Kotar County as compared to healthy peers, and to identify the most pronounced differences in QOL between them. The study included 13 children with JIA recruited from the paediatric rheumatology clinic and 17 healthy children from primary school. The children were aged 8-14 years. All participants, including their parents, completed questionnaires to assess the level of their physical activity (Physical Activity Questionnaire for Children; PAQ-C) and QOL (Pediatric Quality of Life Inventory (PedsQLTM) Generic Core and Rheumatology Module scales). Study results showed statistically significant differences in the QOL associated with physical functioning/health (p=0.033), school activities (p=0.008) and psychosocial health (p=0.033) between JIA and control groups. Responses in the rheumatologic questionnaire revealed a statistically significant difference in the QOL associated with pain (p=0.041), daily activities (p=0.011), treatment (p=0.002), concern (p=0.0006) and communication (p=0.0002) between JIA and control groups. The JIA group showed a significantly lower level of physical activity (p=0.008). There was a statistically significant (p=0.0000) correlation between the QOL associated with pain and the QOL associated with physical functioning/health (r=0.94), emotional functioning (r=0.71), social functioning (r=0.74), school functioning (r=0.56) and psychosocial health (r=0.80). In conclusion, study results suggested JIA to affect QOL in almost all domains in the affected primary school children, with the greatest differences from their healthy peers being recorded in the QOL associated with worrying and communicating about their illness.","PeriodicalId":49715,"journal":{"name":"Paediatria Croatica","volume":"63 1","pages":"145-152"},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46130215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Kljenak, M. Bašković, Domagoj Pešorda, A. Pleskov, M. Ilić, S. Sušić
{"title":"Innovative advantages of the Zagreb surgical protocol of hand reconstruction in patients with epidermolysis bullosa","authors":"A. Kljenak, M. Bašković, Domagoj Pešorda, A. Pleskov, M. Ilić, S. Sušić","doi":"10.13112/pc.2019.34","DOIUrl":"https://doi.org/10.13112/pc.2019.34","url":null,"abstract":"","PeriodicalId":49715,"journal":{"name":"Paediatria Croatica","volume":"63 1","pages":"160-167"},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43808329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dragica Šakić, M. Jovančević, Zrinka Šakić, I. Jurin, Giovana Armano, Sonja Oković
levels are usually less than fivefold and hyperbilirubi-naemia is seen in up to 5% of patients. In our patient ALT increased more than 30 times and she became clinically jaundiced and symptomatic. Fulminant hepatitis is very rare. Possible mechanisms are lymphocytic infiltration of hepatocytes, cholestasis and auto-immune hepatitis. Treatment is mainly symptomatic and supportive. Conclusion Patients with IMN should be observed for jaundice and subsequently monitored for liver function in case of hepatitis. EBV should be considered in patients presenting with clinical jaundice.
{"title":"Recognising risk factors in paediatric population for cardiovascular disease development in adulthood","authors":"Dragica Šakić, M. Jovančević, Zrinka Šakić, I. Jurin, Giovana Armano, Sonja Oković","doi":"10.13112/pc.2019.30","DOIUrl":"https://doi.org/10.13112/pc.2019.30","url":null,"abstract":"levels are usually less than fivefold and hyperbilirubi-naemia is seen in up to 5% of patients. In our patient ALT increased more than 30 times and she became clinically jaundiced and symptomatic. Fulminant hepatitis is very rare. Possible mechanisms are lymphocytic infiltration of hepatocytes, cholestasis and auto-immune hepatitis. Treatment is mainly symptomatic and supportive. Conclusion Patients with IMN should be observed for jaundice and subsequently monitored for liver function in case of hepatitis. EBV should be considered in patients presenting with clinical jaundice.","PeriodicalId":49715,"journal":{"name":"Paediatria Croatica","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47805725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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