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Antibacterial Effects of Garlic Ethyl Acetate Fraction (Allium Sativum L.) on the Growth Of Bacteria Staphylococcus aureus and Escherichia coli 大蒜乙酸乙酯部分对金黄色葡萄球菌和大肠杆菌生长的抑菌作用
Pub Date : 2023-08-06 DOI: 10.26714/magnamed.10.2.2023.163-169
Larasati Juninda, Listiana Masyita Dewi, Retno Sintowati, Rochmadina Suci Bestari
Background: Antibiotics are a treatment used to treat bacterial infections. However, the many antibiotic-resistant bacteria caused researchers to use plants as an alternative treatment, one of which is garlic (Allium sativum L.).Objective: Previous research stated that the diameter of the inhibition zone by garlic had a more excellent value than the antibiotics used. Hence, the researchers were interested in conducting an antibacterial test of the ethyl acetate fraction of garlic against the growth of Staphylococcus aureus and Escherichia coli.Methods: This study was an experimental laboratory using the posttest-only control group design method in the Kruskal Wallis test data analysis.Results: the results of the inhibition analysis with p-value < 0.05 in each test group for both Staphylococcus aureus and Escherichia coli. With the Mann-Whitney test, the results obtained a p-value <0.005 for each bacteria and test group. The most significant value, namely p= 0.002. This result shows significant differences between the test groups for each bacterium.Conclusion: There is an antibacterial effect of the ethyl acetate fraction of garlic (Allium sativum L.) at concentrations of 25%, 50%, and 100% against the growth of Staphylococcus aureus and Escherichia coli
背景:抗生素是一种用于治疗细菌感染的治疗方法。然而,许多耐抗生素细菌导致研究人员使用植物作为替代治疗,其中之一是大蒜(Allium sativum L.)。目的:前人研究表明大蒜抑菌圈直径比常用抗生素具有更优的抑菌价值。因此,研究人员对大蒜的乙酸乙酯部分对金黄色葡萄球菌和大肠杆菌生长的抑菌试验很感兴趣。方法:本研究采用Kruskal - Wallis检验数据分析的后测纯对照组设计方法。结果:p值<的抑制分析结果;金黄色葡萄球菌和大肠杆菌在各试验组中均为0.05。通过Mann-Whitney检验,各细菌和试验组的p值均为<0.005。最显著值,即p= 0.002。这一结果显示了每种细菌在测试组之间的显著差异。结论:大蒜(Allium sativum L.)乙酸乙酯部位在浓度为25%、50%和100%时对金黄色葡萄球菌和大肠杆菌的生长均有抑制作用
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引用次数: 0
Potential Ekstract Of Red Betel Leaf (Piper crocatum Ruiz & Pav.) as a Natural Hand Sanitizer 红槟榔叶(Piper crocatum Ruiz &Pav.)作为天然洗手液
Pub Date : 2023-08-06 DOI: 10.26714/magnamed.10.2.2023.141-149
Maya Monica Manurung, Tyas Hanurita Subekti, Nanda Dhea Ayu Sawitri, Iin Novita Nurhidayati Mahmuda
Background: Hands are the most common medium for spreading disease. Red betel leaf has antibacterial bioactive compounds such as flavonoids, alkaloids, polyphenols, tannins, and essential oils. The most common way to clean hands is to use hand sanitizer.Objective: To determine the antibacterial potential of red betel leaf extract (Piper crocatum Ruiz & Pav.) against the growth of Staphylococcus aureus, Streptococcus pyogenes, and Salmonella typhi as an active ingredient in hand sanitizers. Methods: Each bacterium, namely Staphylococus aureus, Streptococcus pyogenes and Salmonella typhi were divided into 6 groups, PEG 5% as a negative control, clindamycin for Staphylococus aureus and Streptococcus pyogenes and chloramphenicol for Salmonella typhi as a positive control, 70% alcohol as a comparison for hand sanitizer, extract 20%, 40%, and 80% as treatment groups. The obstacle zone is measured using a ruler.Results: Zones of inhibition against Staphylococus aureus, Streptococcus pyogenes, and Salmonella typhi were formed at concentrations of 20%, 40%, and 80%. Kruskal Wallis statistical analysis showed significant results with p=0.000.Conclusion: Red betel leaf extract has statistically significant antibacterial activity against Staphylococcus aureus, Streptococcus pyogenes and Salmonella typhi. The extract concentration of 40% is the optimal concentration as a raw material for hand sanitizer.
背景:手是传播疾病最常见的媒介。红槟榔叶含有抗菌生物活性化合物,如类黄酮、生物碱、多酚、单宁和精油。最常用的洗手方法是使用洗手液。目的:测定红槟榔叶提取物的抑菌潜力;(Pav.)作为洗手液中的一种有效成分,可以抑制金黄色葡萄球菌、化脓性链球菌和伤寒沙门氏菌的生长。方法:将每种细菌,即金黄色葡萄球菌、化脓性链球菌和伤寒沙门菌分为6组,5% PEG为阴性对照,5%林霉素为金黄色葡萄球菌、化脓性链球菌和氯霉素为伤寒沙门菌阳性对照,70%酒精为对照洗手液,提取液20%、40%和80%为治疗组。障碍物区域用尺子测量。结果:金黄色葡萄球菌、化脓性链球菌和伤寒沙门菌在浓度为20%、40%和80%时形成抑制区。Kruskal Wallis统计分析结果p=0.000。结论:槟榔叶提取物对金黄色葡萄球菌、化脓性链球菌和伤寒沙门氏菌具有显著的抑菌活性。提取液的浓度为40%是作为洗手液原料的最佳浓度。
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引用次数: 0
Hematological Side Effects Management of Paclitaxel - Carboplatin Chemotherapy in Lung Cancer 紫杉醇-卡铂化疗治疗肺癌血液学副作用的处理
Pub Date : 2023-07-30 DOI: 10.26714/magnamed.10.1.2023.129-140
Kornelis Aribowo, Wiwi Monica Sari
Background: Paclitaxel-carboplatin chemotherapy can cause hema-tological disorders. This regiment's hematological side effects include anemia, neutropenia, and thrombocytopenia. Data showed this regiment side effect occurs with grade iii/iv toxicity anemia, grade III/IV anemia by 41%, neutropenia (78%), and thrombocytopenia (41%). This hema-tological disorder occurs in bone marrow-producing areas due to chemotherapy. Each hematological disorder requires separate interven-tion.Case Presentation: A 54-year-old woman was diagnosed with a progressive disease of left lung adenocarcinoma (Exon 21 mutation) with TKI and received paclitaxel-carboplatin chemotherapy. The patient experienced side effects of anemia, neutropenia, and thrombocytopenia. Anemia was treated with PRC transfusion, neutropenia corrected with Filgrastim, and thrombocytopenia with platelet transfusion. Chemo-therapy was discontinued after five cycles because the Thrombo-cytopenia condition did not improve.Conclusion: Hematological parameters are essential in preparing for lung cancer chemotherapy. Uncorrectable hematological disorders lead to discontinuation of chemotherapy
背景:紫杉醇-卡铂化疗可引起血液学疾病。该团的血液学副作用包括贫血、中性粒细胞减少和血小板减少。数据显示该团的副作用发生在iii/iv级毒性贫血,iii/iv级贫血发生率为41%,中性粒细胞减少症(78%)和血小板减少症(41%)。由于化疗,这种血液学疾病发生在骨髓产生区。每种血液病都需要单独的干预。病例介绍:一名54岁女性被诊断为进展性左肺腺癌(外显子21突变)伴TKI,并接受紫杉醇-卡铂化疗。患者出现了贫血、中性粒细胞减少和血小板减少的副作用。输血治疗贫血,非格昔汀治疗中性粒细胞减少,血小板输注治疗血小板减少。化疗在5个周期后停止,因为血小板减少症没有改善。结论:血液学指标是肺癌化疗前准备的重要指标。无法矫正的血液学疾病导致停止化疗
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引用次数: 0
Multiple Trauma with Severe Brain Injury Cause by Impression Fracture : Case Report and Literature Review 严重颅脑外伤致印性骨折1例并文献复习
Pub Date : 2023-07-30 DOI: 10.26714/magnamed.10.1.2023.117-128
Ahmad Hannan, Khamim Thohari, Khofifah Dwi Oktafiana, Mohammad Hasan, Muhammad Hanun Mahyudin
Background : Multiple trauma one of trauma caused by huge traumatic force involves many organs and tissues. AIS and ISS is scoring for multiple trauma diagnosis and classification. In this Case Report discuss about multiple trauma patient with Severe Brain Injury cause by Impression Fracture with open fracture in regio cruris sinistra and close fracture femur sinistra. Case presentation : The following is a case report of a 63-year-old female patient came to the emergency room of Soegiri Lamongan with decreased of consciousness due to a traffic accident. Mechanism of injury the patient's head hit the chair and the driver's side of the car pillar and the patient's legs were pinched by the car seat. Since 25-year-old patient has a history of uncontrolled diabetes mellitus but the patient regularly takes anti-diabetic drugs (OAD). Patient was diagnosed with multiple trauma with severe brain injury with suspected DAI with open fracture grade 3A middle 1/3 tibia and close fracture middle 1/3 distal femur.Conclusion : Multiple Trauma has a bad prognosis. The most important from Multiple trauma management is prehospotality management. Additional Severe Brain Injury make the diagnosis become worse.
背景:多发创伤是巨大创伤力引起的多器官、多组织损伤之一。AIS和ISS是多重创伤诊断和分类的评分。本病例报告讨论了严重颅脑损伤合并股窦区开放性骨折及股骨窦区闭合性骨折的多重创伤患者。病例介绍:以下是一名63岁女性患者因交通事故而意识下降来到Soegiri Lamongan急诊室的病例报告。损伤机制患者头部撞到椅子和驾驶侧汽车立柱,腿部被汽车座椅挤压。25岁以来,患者有糖尿病控制史,但定期服用降糖药。患者诊断为多处创伤合并重型颅脑损伤,疑似DAI,胫骨中1/3 3A级开放性骨折,股骨远端中1/3闭合性骨折。结论:多发伤预后较差。多重创伤治疗中最重要的是院前治疗。额外的严重脑损伤使诊断变得更糟。
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引用次数: 0
Collaborative Practice between Doctors and Nurses in Patients Management: Attitude of Teamwork 医生和护士在病人管理中的合作实践:团队合作的态度
Pub Date : 2023-02-01 DOI: 10.26714/magnamed.10.1.2023.48-59
Wiwik Kusumawati, Romdzati Romdzati
Background: Interprofessional collaboration is essential in providing higher-quality health services and ensuring patient safety.Objective: This study aims to assess the attitude of cooperation between doctors and nurses as first line health workers in an academic health facility and explore their perspectives on the collaboration attitude between doctors and nurses.Methods: This study used a mixed-method design. The quantitative sample was chosen randomly but with total sampling for the primary clinic. Data on the attitude of cooperation between doctors and nurses from the questionnaire results were analyzed descriptively. The sample for the qualitative study was selected purposively, each health service consisted of 1 doctor and one nurse, so the number of informants was six. The qualitative data were transcribed verbatim and analyzed qualitatively using the constant comparative method.Results: The results showed that of 84 respondents, 54 doctors, and 30 nurses, 95% showed a good teamwork attitude. Some respondents (5%) showed a bad attitude, especially on three items, namely item no 4 (doctors do not have the right to change the treatment plan that has been made), 13 (doctors do not have to be the final determinant) and 18 (possibility of other professions to become leaders). The results of the qualitative analysis show that there are five final themes, namely: 1. teamwork is good; 2. the role of the profession; 3. the importance of interprofessional communication; 4. openness to receive feedback; 5—patient safety and PCC.Conclusion: Both professions have distinct but equal and complementary roles in patient management, each with their own advantages or capabilities. Open communication, which includes getting criticism, can help overcome a poor cooperative attitude.
背景:跨专业协作对于提供更高质量的卫生服务和确保患者安全至关重要。目的:本研究旨在评估学术医疗机构一线医护人员的医护合作态度,并探讨医护人员对医护合作态度的看法。方法:采用混合方法设计。定量样本随机选取,但以总抽样为主。对问卷调查结果中关于医护人员合作态度的数据进行描述性分析。定性研究的样本是有目的选择的,每个卫生服务机构由1名医生和1名护士组成,因此被调查者为6人。将定性资料逐字抄录,并采用恒量比较法进行定性分析。结果:84名受访医生54名,护士30名,95%的受访医生表现出良好的团队合作态度。部分受访者(5%)的态度不太好,特别是在三项上,即第4项(医生无权改变已经制定的治疗方案),第13项(医生不必成为最终决定因素)和第18项(其他职业成为领导者的可能性)。定性分析的结果表明,最终有五个主题,即:1。团队合作很好;2. 专业的作用;3.跨专业沟通的重要性;4. 乐于接受反馈;5 .患者安全和PCC。结论:两种职业在患者管理中各有优势或能力,作用不同,但又平等互补。开放的沟通,包括接受批评,可以帮助克服不良的合作态度。
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引用次数: 0
Mature Teratoma of The Lung : A Case Report 肺成熟畸胎瘤1例报告
Pub Date : 2023-02-01 DOI: 10.26714/magnamed.10.1.2023.109-116
Priangga Adi Wiratama, Alphania Rahniayu, Vira Yasmina Ramadhani
Background: Mature teratoma is a germinal cell tumor that is commonly found in ovaries and testis. Mature teratoma in the lung region is a rare case. According to the literature there are only 67 cases worldwide starting from 1939 to 2007. There were one cases in Dr. Soetomo general hospital during January 2013 – December 2017.Objective: Mature teratoma in the lung region is a rare case. Presenting in a case report would be beneficial for pathology databaseCase Presentation: A 19 years old man came to hospital with shortness of breath within 3 months ago. It was followed with hemoptysis, trichoptysis and coughing out tooth. CT Scan examination showed an irregular walled cavity with semisolid component and calcification along with a description of "air cresent sign". In thoracotomy tumor excision obtained multilobulated mass size 8.5x6,8x5,6 cm, yellowish-gray white color, and firm consistency. There were also hair and tooth components. The microscopic representation shows pieces of lung tissue with tumor growth coated with squamous epithel with a stroma containing adnexal skin glands, fatty tissue, cartilage tissue, and serous glands (asinar). Discussion: Mature teratoma of the lung is one of the rare tumors, with symptoms of chest pain, hemoptysis, and trichoptysis. Mature teratoma of the lung is generally cystic and multiloculated, but can also be solid, encapsulated. On microscopic examination, shows a picture of various components of ectoderm, mesoderm and endoderm.Conclusion: Mature teratoma of the lung is a rare tumor. Diagnosis was based from clinical findings, radiologic examination, and confirmed with histopathology and immunohistochemistry.
背景:成熟畸胎瘤是一种常见于卵巢和睾丸的生发细胞肿瘤。成熟畸胎瘤在肺区域是一个罕见的病例。根据文献,从1939年到2007年,全世界只有67例。2013年1月至2017年12月期间,Soetomo博士综合医院有1例病例。目的:肺区成熟畸胎瘤是一种罕见的病例。病例报告将有助于病理数据库的建立。病例报告:一名19岁男性,3个月前因呼吸急促入院。随后出现咯血、滴血、咳牙。CT检查显示不规则壁腔,半固体成分,钙化,并描述为“气新月征”。在开胸切除肿瘤时,得到8.5x6、8x5、6 cm的多分叶状肿块,颜色黄灰白色,致密。还有头发和牙齿的成分。显微镜下显示肿瘤生长的肺组织片被鳞状上皮覆盖,间质包含附件皮腺、脂肪组织、软骨组织和浆液腺(腺)。讨论:肺成熟畸胎瘤是一种罕见的肿瘤,其症状为胸痛、咯血、三趾。成熟的肺畸胎瘤通常是囊性的和多室的,但也可以是实心的,被包裹的。镜检显示外胚层、中胚层和内胚层的不同组成部分。结论:肺成熟畸胎瘤是一种罕见的肿瘤。诊断依据临床表现、放射学检查、组织病理学和免疫组织化学证实。
{"title":"Mature Teratoma of The Lung : A Case Report","authors":"Priangga Adi Wiratama, Alphania Rahniayu, Vira Yasmina Ramadhani","doi":"10.26714/magnamed.10.1.2023.109-116","DOIUrl":"https://doi.org/10.26714/magnamed.10.1.2023.109-116","url":null,"abstract":"Background: Mature teratoma is a germinal cell tumor that is commonly found in ovaries and testis. Mature teratoma in the lung region is a rare case. According to the literature there are only 67 cases worldwide starting from 1939 to 2007. There were one cases in Dr. Soetomo general hospital during January 2013 – December 2017.Objective: Mature teratoma in the lung region is a rare case. Presenting in a case report would be beneficial for pathology databaseCase Presentation: A 19 years old man came to hospital with shortness of breath within 3 months ago. It was followed with hemoptysis, trichoptysis and coughing out tooth. CT Scan examination showed an irregular walled cavity with semisolid component and calcification along with a description of \"air cresent sign\". In thoracotomy tumor excision obtained multilobulated mass size 8.5x6,8x5,6 cm, yellowish-gray white color, and firm consistency. There were also hair and tooth components. The microscopic representation shows pieces of lung tissue with tumor growth coated with squamous epithel with a stroma containing adnexal skin glands, fatty tissue, cartilage tissue, and serous glands (asinar). Discussion: Mature teratoma of the lung is one of the rare tumors, with symptoms of chest pain, hemoptysis, and trichoptysis. Mature teratoma of the lung is generally cystic and multiloculated, but can also be solid, encapsulated. On microscopic examination, shows a picture of various components of ectoderm, mesoderm and endoderm.Conclusion: Mature teratoma of the lung is a rare tumor. Diagnosis was based from clinical findings, radiologic examination, and confirmed with histopathology and immunohistochemistry.","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"239 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135202210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Effectiveness of Bitter melon (Momordica charantia L) Extract on Growth of Trichopyton rubrum: In Vitro Study 苦瓜(Momordica charantia L)提取物对红毛藓生长的体外研究
Pub Date : 2023-02-01 DOI: 10.26714/magnamed.10.1.2023.19-26
Vika Pangesty, Ika Dyah Kurniati, Kanti Ratnaningrum
Trichophyton rubrum is type of fungus that most often causes superficial fungal infections. Development of herbal ingredients as antifungal therapy is carried out to find alternative therapies for fungal infections. Bitter melon contains various compounds that have potential to be used as antifungals, including flavonoids and saponins. The aim of this study was to determine the effect of bitter melon extract (Momordica charantia L) on the growth of Trichopyton rubrum. This study used bitter melon extract at concentrations of 5%, 25%, 50%, 75% and 100%. Ketoconazole concentrations of 2% was used as a positive control. Pure cultures of Trichopyton rubrum were diluted using physiological NaCl. Fungal growth was observed microscopically and macroscopically. Results showed that Trichopyton rubrum grew at a concentration of 5% while at concentrations of 25%, 50%, 75% and 100% there was no Trichopyton rubrum growth. Bitter melon extract at a concentration of 25% had similar effect as ketoconazole 2%. Conclusion Bitter melon extract at concentrations of 25%, 50%, 75% and 100% had a similar effect to 2% ketoconazole in inhibiting the growth of Tricophyton rubrum.
红毛癣菌是一种最常引起浅表真菌感染的真菌。开发草药成分作为抗真菌治疗进行寻找替代治疗真菌感染。苦瓜含有多种化合物,包括类黄酮和皂苷,有可能被用作抗真菌剂。本研究旨在探讨苦瓜提取物对红毛癣菌生长的影响。本研究使用浓度为5%、25%、50%、75%和100%的苦瓜提取物。以2%酮康唑浓度为阳性对照。用生理NaCl对红毛癣菌纯培养物进行稀释。显微镜和宏观观察真菌生长情况。结果表明,在浓度为5%时,红毛滴虫生长,而在浓度为25%、50%、75%和100%时,红毛滴虫均未生长。25%浓度的苦瓜提取物与2%浓度的酮康唑效果相近。结论25%、50%、75%和100%浓度的苦瓜提取物对红毛癣菌的抑制作用与2%酮康唑相似。
{"title":"Effectiveness of Bitter melon (Momordica charantia L) Extract on Growth of Trichopyton rubrum: In Vitro Study","authors":"Vika Pangesty, Ika Dyah Kurniati, Kanti Ratnaningrum","doi":"10.26714/magnamed.10.1.2023.19-26","DOIUrl":"https://doi.org/10.26714/magnamed.10.1.2023.19-26","url":null,"abstract":"Trichophyton rubrum is type of fungus that most often causes superficial fungal infections. Development of herbal ingredients as antifungal therapy is carried out to find alternative therapies for fungal infections. Bitter melon contains various compounds that have potential to be used as antifungals, including flavonoids and saponins. The aim of this study was to determine the effect of bitter melon extract (Momordica charantia L) on the growth of Trichopyton rubrum. This study used bitter melon extract at concentrations of 5%, 25%, 50%, 75% and 100%. Ketoconazole concentrations of 2% was used as a positive control. Pure cultures of Trichopyton rubrum were diluted using physiological NaCl. Fungal growth was observed microscopically and macroscopically. Results showed that Trichopyton rubrum grew at a concentration of 5% while at concentrations of 25%, 50%, 75% and 100% there was no Trichopyton rubrum growth. Bitter melon extract at a concentration of 25% had similar effect as ketoconazole 2%. Conclusion Bitter melon extract at concentrations of 25%, 50%, 75% and 100% had a similar effect to 2% ketoconazole in inhibiting the growth of Tricophyton rubrum.","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135202003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship of Exclusive Breastfeeding with The Incidence of Acute Respiratory Infections in Toddlers at The Ringinarum Health Center Kendal Regency 纯母乳喂养与幼童急性呼吸道感染发生率的关系
Pub Date : 2023-02-01 DOI: 10.26714/magnamed.10.1.2023.60-66
Izza Alya Ardana Putri, Astin Prima Sari, Ika Dyah Kurniati
Background: Acute Respiratory Infection (ARI) is an acute infection affecting the nose, paranasal sinuses, pharynx, trachea, bronchi, lungs, and epiglottis. ARI is the main cause of mortality and morbidity in toddlers in the world. The incidence of ARI can be prevented by exclusive breastfeeding.Objective: To prove the correlation of exclusive breastfeeding with the incidence of ARI in toddlersMethods: This case-control study conducted on December 2021 at the Ringinarum Health Center Kendal Regency. Sampling was conducted by purposive sampling method and was conducted based on inclusion and exclusion criterias.Results: The total samples obtained in this study were 124 samples. This study showed that the characteristics of toddlers with ARI among others the most frequent age is 24-35 months (30,6%), most of them were male (61,3%) and weren’t exclusively breastfed (69,4%). Futhermore, this study also found that there was a correlation between exclusivity of breastfeeding and the incidence of ARI in toddlers (p<0,05). Toddlers who weren’t exclusively breastfed had 5,5 times greater risk of ARI than those who were exclusively breastfed (OR>1).Conclusion: There is a correlation between exclusive breastfeeding with the incidence of acute respiratory infections in toddlers.
背景:急性呼吸道感染(ARI)是一种影响鼻、鼻窦、咽部、气管、支气管、肺和会厌的急性感染。急性呼吸道感染是全世界幼儿死亡和发病的主要原因。纯母乳喂养可以预防急性呼吸道感染的发生。目的:证明纯母乳喂养与婴幼儿ARI发病率的相关性。方法:本病例对照研究于2021年12月在肯德尔县Ringinarum卫生中心进行。采用目的抽样方法,根据纳入标准和排除标准进行抽样。结果:本研究共获得124份样本。本研究表明,ARI患儿的特点是24-35个月最常见(30.6%),大多数为男性(61.3%),非纯母乳喂养(69.4%)。此外,本研究还发现,纯母乳喂养与幼儿ARI发病率之间存在相关性(p< 0.05)。非纯母乳喂养的幼儿患ARI的风险是纯母乳喂养幼儿的5.5倍(OR>1)。结论:纯母乳喂养与幼儿急性呼吸道感染发生率存在相关性。
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引用次数: 0
Sedentary Lifestyle Phenomenon and Obesity Risk on Students at School and College during Transitions from Conventional School to Online School 从传统学校到网络学校过渡时期中学生的久坐生活方式现象和肥胖风险
Pub Date : 2023-02-01 DOI: 10.26714/magnamed.10.1.2023.93-108
Diana Putri Wibowo, Kartika Prahasanti, M. Reza Utama, Aprilia Paramitasari, Absa Secka
Background: Online School was actively carried out during the COVID-19 pandemic in order to reduce social interaction, minimize outdoor activities, and decreasing airborne virus transmission. This activities mainly uses virtual media. During activities, students are advised and ordered to stay inside their house, which causes reduction towards physical activities. Said actions, causes a significant change in their lifestyle and can increase the risk of obesity.Objective: To find out the phenomenon of obesity in conventional education school students, from elementary to high school, during the transition from face-to-face learning to long distance learning.Methods: Reviewing several published scientific articles regarding the phenomenon of increased risk of obesity due to online school during the COVID-19 Pandemic.Results: There is a relationship between online school that increased risk of obesity where are sedentary behavior, stress, and diet. This is because online school makes decreased physical activity, increased screen time, irregular sleep patterns, and stress. This can be experienced by any students.Conclusion: Online learning during the COVID-19 pandemic is proven to escalate risks in students becoming obese, according to an additional increase in their sedentary lifestyle. Hence a modification in their lifestyle and routine is highly needed.
背景:为减少社交活动,减少户外活动,减少病毒通过空气传播,在新冠肺炎大流行期间积极开展网络学校。该活动主要使用虚拟媒体。在活动期间,学生们被建议并被命令呆在家里,这导致了体育活动的减少。这些行为会导致他们的生活方式发生重大变化,并可能增加肥胖的风险。目的:了解传统教育学校学生在由面对面学习向远程学习过渡过程中的肥胖现象。方法:回顾新冠肺炎大流行期间网络学校导致肥胖风险增加现象的多篇已发表的科学文章。结果:网络学校增加肥胖风险与久坐行为、压力和饮食之间存在关系。这是因为在线学校减少了身体活动,增加了屏幕时间,不规律的睡眠模式和压力。这是任何学生都能体会到的。结论:在COVID-19大流行期间,在线学习被证明会增加学生肥胖的风险,因为他们久坐不动的生活方式会增加。因此,改变他们的生活方式和日常生活是非常必要的。
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引用次数: 0
Diabetic Wound Healing Activity of Anabas testudineus Fish Scales 泥鳅鱼鳞对糖尿病创面愈合活性的影响
Pub Date : 2023-02-01 DOI: 10.26714/magnamed.10.1.2023.40-47
Erwin Rosadi, Lia Yulia Budiarti, Bhisma Ridho Romadhon, Nida Nurkhalishah, Nur Salsabila Apriliani Risma Putri, Nur Azmina Aisyah, Isnaini Isnaini
Background: Anabas testudineus fish scales are part of the fish that has not been used optimally. Fish scales contain chitin. Chitin which undergoes deacetylation, produces chitosan. Chitosan is an efficacious compound for antibacterial and diabetic wound healing.Objective: This study aimed to extract chitosan from fish scales and test the diabetic wound healing activity of fish scale extract gelMethods: Extraction of fish scales using 0.3 M NaOH, 0.55 M HCl, and 50% NaOH. FTIR will analyze the extraction results to see the functional groups of the extract. Activity test of fish scale extracts diabetic wound healing gel was carried out on Rattus novergicus Wistar strain for 14 days. There were five treatments: negative control, positive control given octenillinR, and fish scale extract gel conc. 5%, 10%, and 15%.Results: The results showed that the fish scales extract contained chitosan, and gel extract fish scale conc 5% have diabetic wound healing activity better than 10% and 15%. Conclusion: A. testudineus fish scale extract contains chitosan, as seen from the FTIR results.
背景:泥鳅鱼鳞是鱼类中尚未得到充分利用的部分。鱼鳞含有几丁质。几丁质经过去乙酰化,产生壳聚糖。壳聚糖是一种有效的抗菌和糖尿病伤口愈合的化合物。目的:从鱼鳞中提取壳聚糖,考察鱼鳞提取物凝胶对糖尿病创面的愈合作用。方法:用0.3 M NaOH、0.55 M HCl、50% NaOH提取鱼鳞。FTIR将分析提取结果,以查看提取物的官能团。对糖尿病创面愈合凝胶鱼鳞提取物对褐家鼠Wistar菌株进行了14 d的活性试验。共设5个处理:阴性对照组、阳性对照组和鱼鳞提取物凝胶对照组。5%, 10%和15%。结果:鱼鳞提取物含壳聚糖,鱼鳞凝胶提取物含壳聚糖5%,其糖尿病创面愈合活性优于10%和15%。结论:从红外光谱分析可以看出,龙蚌鱼鳞提取物中含有壳聚糖。
{"title":"Diabetic Wound Healing Activity of Anabas testudineus Fish Scales","authors":"Erwin Rosadi, Lia Yulia Budiarti, Bhisma Ridho Romadhon, Nida Nurkhalishah, Nur Salsabila Apriliani Risma Putri, Nur Azmina Aisyah, Isnaini Isnaini","doi":"10.26714/magnamed.10.1.2023.40-47","DOIUrl":"https://doi.org/10.26714/magnamed.10.1.2023.40-47","url":null,"abstract":"Background: Anabas testudineus fish scales are part of the fish that has not been used optimally. Fish scales contain chitin. Chitin which undergoes deacetylation, produces chitosan. Chitosan is an efficacious compound for antibacterial and diabetic wound healing.Objective: This study aimed to extract chitosan from fish scales and test the diabetic wound healing activity of fish scale extract gelMethods: Extraction of fish scales using 0.3 M NaOH, 0.55 M HCl, and 50% NaOH. FTIR will analyze the extraction results to see the functional groups of the extract. Activity test of fish scale extracts diabetic wound healing gel was carried out on Rattus novergicus Wistar strain for 14 days. There were five treatments: negative control, positive control given octenillinR, and fish scale extract gel conc. 5%, 10%, and 15%.Results: The results showed that the fish scales extract contained chitosan, and gel extract fish scale conc 5% have diabetic wound healing activity better than 10% and 15%. Conclusion: A. testudineus fish scale extract contains chitosan, as seen from the FTIR results.","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"15 9","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135202001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Magna Medica
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