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Occupational Physicians' Management of Workers With Multiple Sclerosis in Italy: Results From a Survey. 意大利职业医师对多发性硬化症患者的管理:调查结果
IF 2.4 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-06-21 DOI: 10.23749/mdl.v115i3.16038
Bruna Maria Rondinone, Giuliana Buresti, Sergio Iavicoli, Paolo Durando, Mario Alberto Battaglia, Guglielmo Dini, Alfredo Montecucco, Alborz Rahmani, Nicoletta Debarbieri, Paolo Bandiera, Michela Ponzio, Tommaso Manacorda, Elena Pignattelli, Matilde Inglese, Benedetta Persechino

Background: This study, conducted on a sample of Italian occupational physicians (OPs), aimed to gather data regarding professional activity and their needs in managing workers with multiple sclerosis.

Methods: A convenience sample of OPs recruited by e-mail invitation to the list of Italian Society of Occupational Medicine members was considered. A total of 220 OPs participated between July and October 2022. An ad hoc questionnaire was developed based on previous survey experiences. It investigated, among others, the characteristics of OP respondents, the evaluation of fitness for work issues, and the OP training and updating needs on multiple sclerosis and work.

Results: Ninety-one percent of OPs had to assess the fitness for work of workers with multiple sclerosis during their activity. Sixty-four percent experienced particular difficulties in issuing a fitness for work judgment. Regarding the level of knowledge on multiple sclerosis, 54% judged it sufficient. The "Assessment of fitness for work for the specific task" and the "Role of the OPs in identifying reasonable accommodations" were the most interesting training topics regarding MS management in work contexts chosen by the respondents.

Conclusions: The interest in the work inclusion and job retention of people with disability, particularly the aspects linked to the Identification and implementation of reasonable accommodations, will require integration with the occupational safety and health protection system and will undoubtedly impact the OP's activities.

研究背景本研究以意大利职业医师(OPs)为样本,旨在收集有关多发性硬化症患者管理方面的职业活动及其需求的数据:方法:通过电子邮件邀请意大利职业医学会会员名单中的职业医师进行抽样调查。2022年7月至10月期间,共有220名职业医师参与。根据以往的调查经验制定了一份特别问卷。除其他外,问卷还调查了多发性硬化症患者的特征、工作适应性评估、多发性硬化症和工作方面的培训和更新需求:结果:91%的手术医生在工作中需要评估多发性硬化症患者的工作适应性。64%的操作员在做出是否适合工作的判断时遇到了特殊困难。关于多发性硬化症的知识水平,54% 的人认为足够。受访者最感兴趣的培训主题是 "特定任务的工作适应性评估 "和 "操作人员在确定合理便利措施中的作用":结论:对残疾人工作融入和工作保留的关注,特别是与合理便利措施的确定和实施相关的方面,需要与职业安全和健康保护系统相结合,这无疑会对业务官员的活动产生影响。
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引用次数: 0
Job Retention by People With Disabilities: A Qualitative Study of the Perspectives of People With Multiple Sclerosis. 残疾人保留工作:多发性硬化症患者视角的定性研究》。
IF 2.4 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-06-21 DOI: 10.23749/mdl.v115i3.15947
Michela Ponzio, Elena Pignattelli, Anna Verri, Erica Grange, Benedetta Persechino, Bruno Kusznir Vitturi, Paolo Bandiera, Tommaso Manacorda, Matilde Inglese, Paolo Durando, Mario Alberto Battaglia

Background: Multiple sclerosis (MS), because of its early age at onset, greatly impacts the working lives of those affected by it in ways linked to different factors, both professional and personal. It has been observed that only a small percentage (20-40%) of workers with MS retain their jobs after the diagnosis. When identifying factors determining job retention or loss in this setting, it is essential to consider the direct perspectives of people with MS (PwMS).

Methods: A qualitative study, based on the conduction of two focus groups, was conducted to explore the personal experiences of PwMS who work.

Results: The results show that there are numerous factors, both positive and negative, that can influence these people's ability to retain their jobs. The climate established in the workplace and the relationship between workers with MS and their colleagues were fundamentally important aspects, as was knowledge of the disease at the level of public opinion.

Conclusions: Managing work is a complex undertaking for people with a disabling condition like MS. There needs to be greater awareness of the employment rights of PwMS. Improving these knowledge-based aspects could undoubtedly improve the quality of the working lives of PwM.

背景:多发性硬化症(MS)由于发病年龄较早,对患者的工作生活造成了很大影响,这些影响与不同的因素有关,既有职业因素,也有个人因素。据观察,只有一小部分(20%-40%)多发性硬化症患者在确诊后能够保住工作。在确定这种情况下决定保留或失去工作的因素时,必须考虑多发性硬化症患者(PwMS)的直接观点:方法:在开展两个焦点小组的基础上,进行了一项定性研究,以探讨工作中的多发性硬化症患者的个人经历:结果:研究结果表明,有许多积极和消极的因素会影响这些人保住工作的能力。工作场所的氛围以及多发性硬化症患者与同事之间的关系是最重要的因素,公众舆论对该疾病的了解也是如此:对于像多发性硬化症这样的致残性疾病患者来说,工作管理是一项复杂的工作。需要提高对多发性硬化症患者就业权利的认识。改善这些基于知识的方面无疑可以提高 PwM 的工作生活质量。
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引用次数: 0
The Digital Economy and Hybrid Work Call for a Review of Compensation Criteria for Musculoskeletal Disorders. 数字经济和混合型工作要求对肌肉骨骼疾病的赔偿标准进行审查。
IF 2.4 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-06-21 DOI: 10.23749/mdl.v115i3.16072
Yves Roquelaure, Julie Bodin, Florence Cros, Alexis Descatha, Marc Fadel

Work-related musculoskeletal disorders (WRMSD) pose a significant occupational health challenge in Europe. The digitization of the economy substantially reshaped the nature and organization of work. The proliferation of hybrid working, characterized by a combination of office-based and remote work, has been accelerated by the COVID-19 pandemic. This review covers hybrid forms of work, their impact on WRMSDs, and the potential implications for WRMSD compensation. Approximately 30-40% of the European workforce could potentially transition to hybrid forms of work. Hybrid work arrangements can result in prolonged static postures of the trunk, neck, and upper limbs without adequate breaks, thereby increasing the risk of neck and lower back pain. As teleworking and hybrid working become more prevalent, an increase in non-specific WRMSDs is anticipated among the working population. In many countries, claims for WRMSDs necessitate a formal diagnosis by a healthcare professional. However, cases of non-specific WRMSDs, such as cervicalgia or chronic shoulder pain, - commonly observed in sedentary workers engaged in predominantly low-intensity, prolonged static work amid visually and cognitively demanding tasks - often do not meet the criteria for compensation as occupational diseases. The compensation system and/or the criteria for compensation must be adapted to accommodate the rise of telework, necessitating evolving criteria for compensation that address both medical and risk exposure considerations.

在欧洲,与工作相关的肌肉骨骼疾病(WRMSD)对职业健康构成了重大挑战。经济的数字化极大地改变了工作的性质和组织形式。COVID-19大流行加速了以办公室工作和远程工作相结合为特征的混合工作方式的普及。本综述涉及混合工作形式、其对 WRMSD 的影响以及对 WRMSD 补偿的潜在影响。大约 30-40% 的欧洲劳动力有可能过渡到混合工作形式。混合工作安排会导致躯干、颈部和上肢长时间处于静态姿势,没有适当的休息时间,从而增加颈部和下背部疼痛的风险。随着远程工作和混合工作越来越普遍,预计工作人群中的非特异性 WRMSD 会增加。在许多国家,WRMSD 的索赔必须由医疗保健专业人员进行正式诊断。然而,非特异性 WRMSDs(如颈椎痛或慢性肩痛)--通常见于主要从事低强度、长时间静态工作的久坐工人,以及视觉和认知要求较高的任务--往往不符合职业病赔偿标准。必须对补偿制度和/或补偿标准进行调整,以适应远程工作的兴起,这就需要不断发展补偿标准,既要考虑医疗因素,又要考虑风险暴露因素。
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引用次数: 0
Artificial Intelligence and Occupational Health and Safety, Benefits and Drawbacks. 人工智能与职业健康和安全,利与弊。
IF 2.7 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-04-24 DOI: 10.23749/mdl.v115i2.15835
Mohamed El-Helaly

This paper discusses the impact of artificial intelligence (AI) on occupational health and safety. Although the integration of AI into the field of occupational health and safety is still in its early stages, it has numerous applications in the workplace. Some of these applications offer numerous benefits for the health and safety of workers, such as continuous monitoring of workers' health and safety and the workplace environment through wearable devices and sensors. However, AI might have negative impacts in the workplace, such as ethical worries and data privacy concerns. To maximize the benefits and minimize the drawbacks of AI in the workplace, certain measures should be applied, such as training for both employers and employees and setting policies and guidelines regulating the integration of AI in the workplace.

本文讨论了人工智能(AI)对职业健康与安全的影响。虽然人工智能与职业健康和安全领域的结合仍处于早期阶段,但它在工作场所有许多应用。其中一些应用为工人的健康和安全带来了诸多益处,例如通过可穿戴设备和传感器对工人的健康和安全以及工作场所环境进行持续监测。然而,人工智能可能会给工作场所带来负面影响,如道德担忧和数据隐私问题。为了最大限度地发挥人工智能在工作场所的益处,减少其弊端,应采取一些措施,如对雇主和雇员进行培训,制定政策和指导方针,规范人工智能在工作场所的应用。
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引用次数: 0
Exposure Assessment and Monitoring of Antiblastic Drugs Preparation in Health Care Settings: A Systematic Review. 医疗机构中抗原药物配制的暴露评估和监测:系统回顾
IF 2.4 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-04-24 DOI: 10.23749/mdl.v115i2.15609
Francesca Borghi, Carolina Zellino, Arianna Zago, Giovanni De Vito, Rocco Loris Del Vecchio, Andrea Cattaneo, Andrea Spinazzè, Domenico Maria Cavallo

Several antiblastic drugs (ADs) are classified as carcinogenic, mutagenic, and/or toxic for reproduction. Despite established guidelines and safe handling technologies, ADs contamination of the work environments could occur in healthcare settings, leading to potential exposure of healthcare staff. This systematic review aims to investigate the main techniques and practices for assessing ADs occupational exposure in healthcare settings. The reviewed studies unveil that workplace contamination by ADs appears to be a still-topical problem in healthcare settings. These issues are linked to difficulties in guaranteeing: (i) the adherence to standardized protocols when dealing with ADs, (ii) the effective use of personal protective equipment by operators involved in the administration or management of ADs, (iii) a comprehensive training of the healthcare personnel, and (iv) a thorough health surveillance of exposed workers. A "multi-parametric" approach emerges as a desirable strategy for exposure assessment. In parallel, exposure assessment should coincide with the introduction of novel technologies aimed at minimizing exposure (i.e., risk management). Assessment must consider various departments and health operators susceptible to ADs contamination, with a focus extended beyond worst-case scenarios, also considering activities like surface cleaning and logistical tasks related to ADs management. A comprehensive approach in ADs risk assessment enables the evaluation of distinct substance behaviors and subsequent exposure routes, affording a more holistic understanding of potential risks.

有几种抗肿瘤药物(ADs)被归类为致癌、诱变和/或生殖毒性药物。尽管有既定的指导原则和安全处理技术,但在医疗机构中仍可能发生工作环境中的ADs污染,从而导致医护人员的潜在暴露。本系统综述旨在调查医疗机构中评估反式脂肪酸职业暴露的主要技术和实践。综述的研究结果表明,在医疗机构中,工作场所的反式脂肪酸污染似乎仍然是一个棘手的问题。这些问题与难以保证以下几点有关:(i) 在处理反式脂肪酸时遵守标准化规程,(ii) 参与反式脂肪酸管理的操作人员有效使用个人防护设备,(iii) 对医护人员进行全面培训,以及 (iv) 对暴露于反式脂肪酸的工作人员进行全面的健康监测。"多参数 "方法是暴露评估的理想策略。与此同时,暴露评估应与旨在尽量减少暴露的新技术(即风险管理)的引进同步进行。评估必须考虑易受反式脂肪酸污染的各个部门和卫生操作人员,重点不仅放在最坏情况下,还要考虑与反式脂肪酸管理相关的表面清洁和后勤任务等活动。采用综合方法进行反式脂肪酸风险评估,可对不同的物质行为和随后的接触途径进行评估,从而更全面地了解潜在风险。
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引用次数: 0
Occupational Risk for Coronary Artery Disease in Shift Workers - A Systematic Review. 轮班工人患冠状动脉疾病的职业风险--系统回顾。
IF 2.7 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-04-24 DOI: 10.23749/mdl.v115i2.15532
Gabriele D'Ettorre, Prisco Piscitelli, Vincenza Pellicani, Roberta Tornese, Giancarlo Ceccarelli, Gabriella D'Ettorre, Giuseppe La Torre

Background: Coronary artery disease (CAD) prevention in shift workers (SWs) poses a significant challenge worldwide, as CAD remains a major cause of mortality and disability. In the past, SWs were found at higher risk of CAD than non-s SWs. Nevertheless, the pathogenic mechanism between shift work and CAD to date is unclear. This systematic review aims to enhance understanding of the risk of CAD occurrence in SWs.

Methods: A systematic literature review was conducted from January 2013 to December 2023. MEDLINE/Pubmed databases were used initially, and additional relevant studies were searched from references. Shift work was defined as any schedule outside traditional shifts, including the night shift.

Results: Fifteen pertinent papers were categorized into risk assessment or risk management. Findings demonstrated an increased risk of CAD among SWs compared to non-SWs, with an increased CAD risk observed for both shift work and night shift work.

Discussion: Duration-response associations indicate that greater shift exposure is linked to higher CAD risk. SWs incur an increased risk of CAD through the atherosclerotic process. As shift work duration increases as the risk of atherosclerosis is higher, workers demonstrate a higher prevalence and severity of coronary artery plaques.

Conclusions: The evidence-based results underscore the increased risk of CAD in SWs and are sufficient for proposing guidelines aimed at reducing the risk of CAD in SWs and at managing people with CAD in return to work characterized by disrupted circadian rhythms.

背景:轮班工人(SWs)的冠状动脉疾病(CAD)预防是全球面临的一项重大挑战,因为 CAD 仍然是导致死亡和残疾的主要原因。过去,人们发现轮班工人比非轮班工人患 CAD 的风险更高。然而,轮班工作与 CAD 之间的致病机制至今仍不清楚。本系统性综述旨在加深对社工发生 CAD 风险的了解:方法:对 2013 年 1 月至 2023 年 12 月期间的文献进行了系统性回顾。首先使用 MEDLINE/Pubmed 数据库,然后从参考文献中搜索其他相关研究。轮班工作定义为传统轮班以外的任何时间安排,包括夜班:15篇相关论文分为风险评估和风险管理两类。研究结果表明,与非轮班工作者相比,轮班工作者患 CAD 的风险更高,轮班工作和夜班工作都会增加患 CAD 的风险:讨论:持续时间-反应关联表明,轮班工作时间越长,患 CAD 的风险越高。轮班工作者通过动脉粥样硬化过程增加了患 CAD 的风险。随着轮班工作时间的延长,动脉粥样硬化的风险越高,工人冠状动脉斑块的发病率和严重程度也越高:以证据为基础的研究结果表明,轮班工人罹患冠状动脉粥样硬化症的风险增加,足以提出旨在降低轮班工人罹患冠状动脉粥样硬化症风险的指导原则,以及在昼夜节律紊乱的情况下管理重返工作岗位的冠状动脉粥样硬化症患者。
{"title":"Occupational Risk for Coronary Artery Disease in Shift Workers - A Systematic Review.","authors":"Gabriele D'Ettorre, Prisco Piscitelli, Vincenza Pellicani, Roberta Tornese, Giancarlo Ceccarelli, Gabriella D'Ettorre, Giuseppe La Torre","doi":"10.23749/mdl.v115i2.15532","DOIUrl":"10.23749/mdl.v115i2.15532","url":null,"abstract":"<p><strong>Background: </strong>Coronary artery disease (CAD) prevention in shift workers (SWs) poses a significant challenge worldwide, as CAD remains a major cause of mortality and disability. In the past, SWs were found at higher risk of CAD than non-s SWs. Nevertheless, the pathogenic mechanism between shift work and CAD to date is unclear. This systematic review aims to enhance understanding of the risk of CAD occurrence in SWs.</p><p><strong>Methods: </strong>A systematic literature review was conducted from January 2013 to December 2023. MEDLINE/Pubmed databases were used initially, and additional relevant studies were searched from references. Shift work was defined as any schedule outside traditional shifts, including the night shift.</p><p><strong>Results: </strong>Fifteen pertinent papers were categorized into risk assessment or risk management. Findings demonstrated an increased risk of CAD among SWs compared to non-SWs, with an increased CAD risk observed for both shift work and night shift work.</p><p><strong>Discussion: </strong>Duration-response associations indicate that greater shift exposure is linked to higher CAD risk. SWs incur an increased risk of CAD through the atherosclerotic process. As shift work duration increases as the risk of atherosclerosis is higher, workers demonstrate a higher prevalence and severity of coronary artery plaques.</p><p><strong>Conclusions: </strong>The evidence-based results underscore the increased risk of CAD in SWs and are sufficient for proposing guidelines aimed at reducing the risk of CAD in SWs and at managing people with CAD in return to work characterized by disrupted circadian rhythms.</p>","PeriodicalId":49833,"journal":{"name":"Medicina Del Lavoro","volume":"115 2","pages":"e2024015"},"PeriodicalIF":2.7,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11181222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140867003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk of Skin Cancer in Workers Exposed to Diesel Exhaust: A Systematic Review and Meta-Analysis of Cohort Studies. 接触柴油机废气的工人患皮肤癌的风险:对队列研究的系统回顾和荟萃分析》。
IF 2.7 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-04-24 DOI: 10.23749/mdl.v115i2.15569
Marika D'Agostini, Giulia Collatuzzo, Federica Teglia, Paolo Boffetta

Background: Our objective was to study the association between occupational exposure to diesel exhaust (DE) and skin cancer.

Methods: A systematic review following STROBE guidelines and PECOS criteria was conducted to identify cohort studies describing the association between occupational DE exposure and the risk of skin cancer. We extracted 12 independent risk estimates for melanoma skin cancer (MSC), 8 for non-melanoma skin cancer (NMSC), and 3 for skin cancer not otherwise specified (SC-NOS). Random effects meta-analyses were performed, site-specific and stratified by geographic region and quality score. 95% confidence intervals (CI) were reported. Between-study heterogeneity and potential publication bias were investigated.

Results: There was no overall evidence of an increased risk of MSC [RR=0.90, 95% CI: 0.73-1.11; I2=92.86%, 95% CI: 82.83-97.03%], NMSC [RR=1.04, 95% CI: 0.88-1.23; I2=60.79%, 95% CI: 0-87.34%] or SC-NOS [RR=0.72, 95% CI: 0.54-0.97; I2=26.60%, 95% CI: 0-94.87%] in workers exposed to DE. No difference between low-quality and high-quality studies was found. A stratified analysis by geographical region did not reveal any significant differences. There was no evidence of publication bias.

Conclusions: No evidence of an association between skin cancer and occupational DE exposure was found. Residual confounding and other sources of bias cannot be ruled out.

背景:我们的目的是研究职业暴露于柴油废气(DE)与皮肤癌之间的关系:我们的目标是研究职业暴露于柴油废气(DE)与皮肤癌之间的关系:我们按照 STROBE 指南和 PECOS 标准进行了系统回顾,以确定描述职业性柴油机废气暴露与皮肤癌风险之间关系的队列研究。我们提取了 12 项黑色素瘤皮肤癌 (MSC) 的独立风险估计值、8 项非黑色素瘤皮肤癌 (NMSC) 的独立风险估计值和 3 项非特定皮肤癌 (SC-NOS) 的独立风险估计值。进行了随机效应荟萃分析,针对特定部位,并按地理区域和质量评分进行了分层。报告了 95% 的置信区间 (CI)。对研究之间的异质性和潜在的出版偏差进行了调查:没有总体证据表明暴露于 DE 的工人患 MSC [RR=0.90,95% CI:0.73-1.11;I2=92.86%,95% CI:82.83-97.03%]、NMSC [RR=1.04,95% CI:0.88-1.23;I2=60.79%,95% CI:0-87.34%] 或 SC-NOS [RR=0.72,95% CI:0.54-0.97;I2=26.60%,95% CI:0-94.87%]的风险增加。低质量研究与高质量研究之间没有差异。按地理区域进行的分层分析未发现任何显著差异。没有证据表明存在发表偏倚:没有证据表明皮肤癌与职业性 DE 暴露有关。不能排除残余混杂因素和其他偏倚来源。
{"title":"Risk of Skin Cancer in Workers Exposed to Diesel Exhaust: A Systematic Review and Meta-Analysis of Cohort Studies.","authors":"Marika D'Agostini, Giulia Collatuzzo, Federica Teglia, Paolo Boffetta","doi":"10.23749/mdl.v115i2.15569","DOIUrl":"10.23749/mdl.v115i2.15569","url":null,"abstract":"<p><strong>Background: </strong>Our objective was to study the association between occupational exposure to diesel exhaust (DE) and skin cancer.</p><p><strong>Methods: </strong>A systematic review following STROBE guidelines and PECOS criteria was conducted to identify cohort studies describing the association between occupational DE exposure and the risk of skin cancer. We extracted 12 independent risk estimates for melanoma skin cancer (MSC), 8 for non-melanoma skin cancer (NMSC), and 3 for skin cancer not otherwise specified (SC-NOS). Random effects meta-analyses were performed, site-specific and stratified by geographic region and quality score. 95% confidence intervals (CI) were reported. Between-study heterogeneity and potential publication bias were investigated.</p><p><strong>Results: </strong>There was no overall evidence of an increased risk of MSC [RR=0.90, 95% CI: 0.73-1.11; I2=92.86%, 95% CI: 82.83-97.03%], NMSC [RR=1.04, 95% CI: 0.88-1.23; I2=60.79%, 95% CI: 0-87.34%] or SC-NOS [RR=0.72, 95% CI: 0.54-0.97; I2=26.60%, 95% CI: 0-94.87%] in workers exposed to DE. No difference between low-quality and high-quality studies was found. A stratified analysis by geographical region did not reveal any significant differences. There was no evidence of publication bias.</p><p><strong>Conclusions: </strong>No evidence of an association between skin cancer and occupational DE exposure was found. Residual confounding and other sources of bias cannot be ruled out.</p>","PeriodicalId":49833,"journal":{"name":"Medicina Del Lavoro","volume":"115 2","pages":"e2024010"},"PeriodicalIF":2.7,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11181223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140867912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cholangiocarcinoma and Occupational Exposure to Asbestos: Insights From the Italian Pooled Cohort Study. 胆管癌与石棉职业暴露:意大利汇集队列研究的启示》。
IF 2.7 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-04-24 DOI: 10.23749/mdl.v115i2.14649
Stefania Curti, Mena Gallo, Daniela Ferrante, Francesca Bella, Lorenza Boschetti, Veronica Casotto, Marcello Ceppi, Daniela Cervino, Lucia Fazzo, Ugo Fedeli, Paolo Giorgi Rossi, Lucia Giovannetti, Paolo Girardi, Cecilia Lando, Enrica Migliore, Lucia Miligi, Enrico Oddone, Vincenza Perlangeli, Roberta Pernetti, Sara Piro, Cinzia Storchi, Rosario Tumino, Amerigo Zona, Manuel Zorzi, Giovanni Brandi, Stefano Ferretti, Corrado Magnani, Alessandro Marinaccio, Stefano Mattioli

Background: Recent studies supported the association between occupational exposure to asbestos and risk of cholangiocarcinoma (CC). Aim of the present study is to investigate this association using an update of mortality data from the Italian pooled asbestos cohort study and to test record linkage to Cancer Registries to distinguish between hepatocellular carcinoma (HCC) and intrahepatic/extrahepatic forms of CC.

Methods: The update of a large cohort study pooling 52 Italian industrial cohorts of workers formerly exposed to asbestos was carried out. Causes of death were coded according to ICD. Linkage was carried out for those subjects who died for liver or bile duct cancer with data on histological subtype provided by Cancer Registries.

Results: 47 cohorts took part in the study (57,227 subjects). We identified 639 causes of death for liver and bile duct cancer in the 44 cohorts covered by Cancer Registry. Of these 639, 240 cases were linked to Cancer Registry, namely 14 CC, 83 HCC, 117 cases with unspecified histology, 25 other carcinomas, and one case of cirrhosis (likely precancerous condition). Of the 14 CC, 12 occurred in 2010-2019, two in 2000-2009, and none before 2000.

Conclusion: Further studies are needed to explore the association between occupational exposure to asbestos and CC. Record linkage was hampered due to incomplete coverage of the study areas and periods by Cancer Registries. The identification of CC among unspecific histology cases is fundamental to establish more effective and targeted liver cancer screening strategies.

背景:最近的研究支持职业暴露于石棉与胆管癌(CC)风险之间存在关联。本研究旨在通过更新意大利石棉队列研究的死亡率数据来调查这种关联,并测试与癌症登记处的记录关联,以区分肝细胞癌(HCC)和肝内/肝外形式的 CC:方法:对一项大型队列研究进行了更新,该研究汇集了意大利 52 个曾接触石棉的工人工业队列。死亡原因根据 ICD 编码。对死于肝癌或胆管癌的受试者与癌症登记处提供的组织学亚型数据进行了关联:47个队列(57227名受试者)参与了研究。在癌症登记处覆盖的 44 个队列中,我们确定了 639 个肝癌和胆管癌死亡原因。在这 639 个病例中,有 240 个病例与癌症登记处有关联,即 14 例 CC、83 例 HCC、117 例组织学不明的病例、25 例其他癌症和 1 例肝硬化(可能是癌前病变)。在14例CC中,12例发生在2010-2019年,2例发生在2000-2009年,没有一例发生在2000年之前:结论:需要进一步研究探讨石棉职业暴露与CC之间的关系。由于癌症登记处对研究地区和时期的覆盖范围不完整,导致记录链接受阻。在非特异性组织学病例中识别CC是制定更有效、更有针对性的肝癌筛查策略的基础。
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引用次数: 0
Mental Disorders Among Healthcare Students Attending a Large University Hospital in Milan, Italy. 在意大利米兰一家大型大学医院就诊的医学生中存在的心理障碍。
IF 2.7 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-04-24 DOI: 10.23749/mdl.v115i2.15168
Marco Mendola, Francesco Masi, Raimondo Castiglione, Antonio Soriano, Safi Zazou, Fabio Tonelli, Paolo Carrer

Background: The high incidence rates, treatment difficulties, and tendency to become chronic, which subsequently affects personal and occupational functioning, make mental health disorders among the most important public health concerns. In this context, healthcare university students (HS) appear to be more vulnerable to psychological distress than others.

Objective: Investigate the prevalence of diagnosed mental illness among different groups of HS to detect students who may be psychologically vulnerable and determine whether the implementation of support interventions is necessary.

Methods: All HS who had a clinical examination performed by an occupational physician at our occupational health unit between 2021 and 2022 were included in our case series. Data were collected and analyzed as part of the occupational physicians' health surveillance program.

Results: out of 679 HS (507 females, 172 males, aged 22.2±3.9 mean±s.d) undergone clinical examination at our Occupational Health Unit, 36 (5.3%) reported a diagnosed psychiatric illness, and 20 were receiving pharmacological therapy at the time of the visit. A higher prevalence of psychological disorders has been highlighted in females (6.1% vs 2.9% in males) and students of the mental health sector (11.1%) when compared with others. A fit-to-work judgment with prescription was necessary for 16.7% of students with mental diseases. The presence of psychiatric disorders was associated with underweight (27.8%) and higher smoking habit (44.4%).

Conclusions: These results underline the necessity of improving the current health surveillance protocols, which should also evaluate students' psychological fragility and implement effective intervention strategies to promote their health and wellbeing.

背景:精神疾病发病率高、治疗困难、易转为慢性,进而影响个人和职业功能,因此是最重要的公共卫生问题之一。在这种情况下,医科大学生(HS)似乎比其他人更容易受到心理困扰:调查不同群体的医学生中确诊精神疾病的患病率,以发现可能存在心理问题的学生,并确定是否有必要实施支持性干预措施:所有在 2021 年至 2022 年期间在本校职业健康科接受过职业医师临床检查的恒生均被纳入我们的病例系列。结果:在职业健康科接受临床检查的 679 名 HS(507 名女性,172 名男性,平均年龄(22.2±3.9)岁)中,有 36 人(5.3%)报告确诊患有精神疾病,20 人在就诊时正在接受药物治疗。与其他人群相比,女性(6.1%,男性为 2.9%)和精神卫生专业学生(11.1%)的心理障碍发病率较高。16.7%的心理疾病学生需要通过处方来判断是否适合工作。精神疾病的存在与体重不足(27.8%)和吸烟习惯较重(44.4%)有关:这些结果表明,有必要改进当前的健康监测方案,还应评估学生的心理脆弱性,并实施有效的干预策略,以促进他们的健康和幸福。
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引用次数: 0
Regulatory and Ethical Considerations on Artificial Intelligence for Occupational Medicine. 人工智能用于职业医学的监管和伦理考虑。
IF 2.7 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-04-24 DOI: 10.23749/mdl.v115i2.15881
Antonio Baldassarre, Martina Padovan

Generative artificial intelligence and Large Language Models are reshaping labor dynamics and occupational health practices. As AI continues to evolve, there's a critical need to customize ethical considerations for its specific impacts on occupational health. Recognizing potential ethical challenges and dilemmas, stakeholders and physicians are urged to proactively adjust the practice of occupational medicine in response to shifting ethical paradigms. By advocating for a comprehensive review of the International Commission on Occupational Health ICOH code of Ethics, we can ensure responsible medical AI deployment, safeguarding the well-being of workers amidst the transformative effects of automation in healthcare.

生成式人工智能和大型语言模型正在重塑劳动动态和职业健康实践。随着人工智能的不断发展,亟需针对其对职业健康的具体影响定制伦理考虑因素。认识到潜在的伦理挑战和困境,我们敦促利益相关者和医生积极调整职业医学实践,以应对不断变化的伦理范式。通过倡导对国际职业健康委员会 ICOH 道德规范进行全面审查,我们可以确保负责任地部署医疗人工智能,在医疗保健领域自动化的变革影响中保障工人的福祉。
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引用次数: 0
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Medicina Del Lavoro
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