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International Journal of Pharmaceutical Research and Development最新文献

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In vitro efficacy of an ayurvedic dentifrice against gingivitis causing pathogen 阿育吠陀牙膏抗牙龈炎病原菌的体外疗效
Pub Date : 2023-01-01 DOI: 10.33545/26646862.2023.v5.i2a.35
Jyoti Singh, Mahesh Katariya, Amit Sirdesai, Prasun Bandyopadhyay
Objective: The objective of this study was to study in vitro efficacy of Ayurvrdic herbs containing toothpaste against oral disease causing pathogens Porphyromonas gingivalis (P. gingivalis). The present study was designed to evaluate in efficacy of the Dabur Red paste containing Ayurvedic herbs like, Kalimirch, Pippali, Tomar, Sunthi, Lavang, Karpura & Pudina for prevention of gum diseases by inhibition of disease causing micro-organism P. gingivalis. Material and Methods: The product was tested against microorganism’s P. gingivalis using agar well diffusion method. The agar-well diffusion method was used to test the antimicrobial effect. Inhibition zones formed around toothpastes after 24 hours of incubation were measured and the data collected were statistically analysed. The time-dependent killing assay was carried out on P. gingivalis. Conclusions: In vitro assessment of ayurvedic paste containing actives like, Kalimirch, Pippali, Tomar, Sunthi, Lavang, Karpura, Pudina and Gairica against gum disease causing oral pathogens revealed the 99.95 % germ kill efficacy of toothpaste against major gingivitis causing oral pathogen P. gingivalis in 2 min contact time.
目的:研究含阿育草药牙膏对口腔致病菌牙龈卟啉单胞菌(P. gingivalis)的体外治疗效果。本研究旨在评估含有阿育吠陀草药如Kalimirch、Pippali、Tomar、Sunthi、Lavang、Karpura和Pudina的Dabur红膏通过抑制致病微生物牙龈卟啉菌来预防牙龈疾病的功效。材料与方法:本品采用琼脂孔扩散法对牙龈假单胞菌进行抑菌试验。采用琼脂孔扩散法测定其抑菌效果。测定牙膏周围培养24小时后形成的抑制带,并对收集到的数据进行统计分析。对牙龈卟啉单胞菌进行了时间依赖性杀灭试验。结论:对含有Kalimirch、Pippali、Tomar、Sunthi、Lavang、Karpura、Pudina、Gairica等活性成分的阿育韦达膏体对口腔病原菌牙龈病的体外抑菌效果进行了评价,结果表明,在2 min接触时间内,对口腔病原菌牙龈炎的抑菌效果达99.95%。
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International Journal of Pharmaceutical Research and Development
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