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Differences in mandibular condyle and glenoid fossa morphology in relation to vertical and sagittal skeletal patterns: A cone-beam computed tomography study. 下颌髁突和盂窝形态与垂直和矢状面骨骼模式的差异:锥束计算机断层扫描研究。
IF 1.9 3区 医学 Q1 Dentistry Pub Date : 2021-03-25 DOI: 10.4041/kjod.2021.51.2.126
Kyoung Jin Noh, Hyoung-Seon Baik, Sang-Sun Han, Woowon Jang, Yoon Jeong Choi

Objective: This study aimed to evaluate the following null hypothesis: there are no differences in the morphology of the temporomandibular joint (TMJ) structures in relation to vertical and sagittal cephalometric patterns.

Methods: This retrospective study was performed with 131 participants showing no TMJ symptoms. The participants were divided into Class I, II, and III groups on the basis of their sagittal cephalometric relationships and into hyperdivergent, normodivergent, and hypodivergent groups on the basis of their vertical cephalometric relationships. The following measurements were performed using cone-beam computed tomography images and compared among the groups: condylar volume, condylar size (width, length, and height), fossa size (length and height), and condyle-to-fossa joint spaces at the anterior, superior, and posterior condylar poles.

Results: The null hypothesis was rejected. The Class III group showed larger values for condylar width, condylar height, and fossa height than the Class II group (p < 0.05). Condylar volume and superior joint space in the hyperdivergent group were significantly smaller than those in the other two vertical groups (p < 0.001), whereas fossa length and height were significantly larger in the hyperdivergent group than in the other groups (p < 0.01). The hypodivergent group showed a greater condylar width than the hyperdivergent group (p < 0.01). The sagittal and vertical cephalometric patterns showed statistically significant interactions for fossa length and height.

Conclusions: TMJ morphology differed across diverse skeletal cephalometric patterns. The fossa length and height were affected by the interactions of the vertical and sagittal skeletal patterns.

目的:本研究旨在评估以下零假设:颞下颌关节(TMJ)结构的形态在垂直和矢状头位测量模式中没有差异。方法:对131名无颞下颌关节症状的参与者进行回顾性研究。参与者根据矢状位头测量关系分为I、II和III类组,根据垂直位头测量关系分为超发散、正常发散和低发散组。使用锥形束计算机断层扫描图像进行以下测量,并在组间进行比较:髁体积、髁大小(宽度、长度和高度)、窝大小(长度和高度)以及前、上、后髁极的髁-窝关节间隙。结果:零假设被否定。III类组髁突宽度、高度、窝高度均大于II类组(p < 0.05)。超发散组的髁突体积和上关节间隙明显小于其他两组(p < 0.001),而窝长和窝高明显大于其他两组(p < 0.01)。低发散组的髁突宽度大于高发散组(p < 0.01)。矢状面和垂直面测量模式显示窝的长度和高度有统计学意义的相互作用。结论:TMJ形态在不同的骨骼头颅测量模式中存在差异。窝的长度和高度受垂直和矢状骨模式的相互作用的影响。
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引用次数: 9
Micro-computed tomography evaluation of general trends in aligner thickness and gap width after thermoforming procedures involving six commercial clear aligners: An in vitro study. 微计算机断层扫描评估热成型后对准器厚度和间隙宽度的总体趋势,涉及六种商业透明对准器:一项体外研究。
IF 1.9 3区 医学 Q1 Dentistry Pub Date : 2021-03-25 DOI: 10.4041/kjod.2021.51.2.135
Mario Palone, Mattia Longo, Niki Arveda, Michele Nacucchi, Fabio De Pascalis, Giorgio Alfredo Spedicato, Giuseppe Siciliani, Luca Lombardo

Objective: To assess the effects of thermoforming on aligner thickness and gap width in six aligner systems with the same nominal thickness.

Methods: Six passive upper aligners of different brands were adapted to a single printed cast. Each sample was evaluated with high-resolution micro-computed tomography. To investigate aligner thickness and gap width, two-dimensional (2D) analysis was conducted assessing the effects of the following variables: tooth type (central incisor, canine, and first molar), 2D reference points, and aligner type. Data were analyzed and compared using analysis of variance and Tukey's post-hoc tests (p < 0.05).

Results: Tooth type, dental region, and aligner type affected both the gap width and aligner thickness. The aligner thickness remained moderately stable across the arch only in the F22.

Conclusions: All thermoformed samples displayed smaller aligner thickness and gap width at anterior teeth and both gingival and coronal centers than at posterior teeth and occlusal surfaces.

目的:评估热成型对六种相同标称厚度的矫直器厚度和间隙宽度的影响。方法:采用六种不同牌号的被动上牙矫直器,分别应用于一种印刷铸造。每个样本都用高分辨率显微计算机断层扫描进行评估。为了研究矫正器的厚度和间隙宽度,进行了二维(2D)分析,评估了以下变量的影响:牙齿类型(中切牙、犬齿和第一磨牙)、二维参考点和矫正器类型。采用方差分析和Tukey事后检验对资料进行分析比较(p < 0.05)。结果:牙型、牙区、矫正器类型对牙间隙宽度和矫正器厚度均有影响。矫正器厚度仅在F22保持适度稳定。结论:所有热成型样品在前牙、牙龈和冠状中心的对准器厚度和间隙宽度均小于后牙和咬合面。
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引用次数: 11
Evaluation of a multi-stage convolutional neural network-based fully automated landmark identification system using cone-beam computed tomographysynthesized posteroanterior cephalometric images. 基于多阶段卷积神经网络的全自动地标识别系统的评价,该系统使用锥束计算机断层扫描合成头前位图像。
IF 1.9 3区 医学 Q1 Dentistry Pub Date : 2021-03-25 DOI: 10.4041/kjod.2021.51.2.77
Min-Jung Kim, Yi Liu, Song Hee Oh, Hyo-Won Ahn, Seong-Hun Kim, Gerald Nelson

Objective: To evaluate the accuracy of a multi-stage convolutional neural network (CNN) model-based automated identification system for posteroanterior (PA) cephalometric landmarks.

Methods: The multi-stage CNN model was implemented with a personal computer. A total of 430 PA-cephalograms synthesized from cone-beam computed tomography scans (CBCT-PA) were selected as samples. Twenty-three landmarks used for Tweemac analysis were manually identified on all CBCT-PA images by a single examiner. Intra-examiner reproducibility was confirmed by repeating the identification on 85 randomly selected images, which were subsequently set as test data, with a two-week interval before training. For initial learning stage of the multi-stage CNN model, the data from 345 of 430 CBCT-PA images were used, after which the multi-stage CNN model was tested with previous 85 images. The first manual identification on these 85 images was set as a truth ground. The mean radial error (MRE) and successful detection rate (SDR) were calculated to evaluate the errors in manual identification and artificial intelligence (AI) prediction.

Results: The AI showed an average MRE of 2.23 ± 2.02 mm with an SDR of 60.88% for errors of 2 mm or lower. However, in a comparison of the repetitive task, the AI predicted landmarks at the same position, while the MRE for the repeated manual identification was 1.31 ± 0.94 mm.

Conclusions: Automated identification for CBCT-synthesized PA cephalometric landmarks did not sufficiently achieve the clinically favorable error range of less than 2 mm. However, AI landmark identification on PA cephalograms showed better consistency than manual identification.

目的:评价基于多阶段卷积神经网络(CNN)模型的自动识别系统对脑后前位(PA)标记的准确性。方法:用个人计算机实现多阶段CNN模型。选取锥束计算机断层扫描(CBCT-PA)合成的430张pa脑图作为样本。用于Tweemac分析的23个地标由一名审核员在所有CBCT-PA图像上手动识别。通过在85张随机选择的图像上重复识别来确认检查员内部的可重复性,这些图像随后被设置为测试数据,在训练前间隔两周。对于多阶段CNN模型的初始学习阶段,使用430张CBCT-PA图像中的345张数据,之后使用之前的85张图像对多阶段CNN模型进行测试。在这85张图片上的第一次人工识别被设置为一个真实的基础。计算平均径向误差(MRE)和成功检出率(SDR)来评估人工识别和人工智能(AI)预测的误差。结果:人工智能的平均MRE为2.23±2.02 mm,误差小于等于2 mm的SDR为60.88%。然而,在重复任务的比较中,人工智能预测到同一位置的标志,而重复人工识别的MRE为1.31±0.94 mm。结论:对cbct合成的PA头侧标志的自动识别未能充分达到小于2 mm的临床有利误差范围。然而,人工智能在PA脑电图上的地标识别比人工识别具有更好的一致性。
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引用次数: 8
Reasons influencing the preferences of prospective patients and orthodontists for different orthodontic appliances. 影响准患者和正畸医师对不同矫治器具偏好的原因。
IF 1.9 3区 医学 Q1 Dentistry Pub Date : 2021-03-25 DOI: 10.4041/kjod.2021.51.2.115
Guido Artemio Marañón-Vásquez, Luísa Schubach da Costa Barreto, Matheus Melo Pithon, Lincoln Issamu Nojima, Matilde da Cunha Gonçalves Nojima, Mônica Tirre de Souza Araújo, Margareth Maria Gomes de Souza

Objective: To evaluate the reasons influencing the preferences for a certain type of orthodontic appliance over another among prospective patients (PP) and orthodontists.

Methods: A total of 49 PP and 51 orthodontists were asked about their preferences for the following appliances: clear aligners (CA), lingual metallic brackets (LMB), polycrystalline and monocrystalline ceramic brackets, and buccal metallic brackets (BMB). The participants rated the importance of 17 potential reasons that would explain their choices. The reasons that contributed most to these preferences were identified. Non-parametric tests (Fisher's exact, χ2 and Mann-Whitney tests) and multivariate analyses (regression and discriminant analysis) were used to assess the data (α = 0.05).

Results: CA and BMB were the most chosen appliances by PP and orthodontists, respectively. LMB was the most rejected option among both groups of participants (p < 0.001). Rates of the importance of pain/discomfort, smile esthetics, finishing details, and feeding/speech impairment showed the highest differences between PP and orthodontists (p < 0.0005). Discriminant analyses showed that individuals who considered treatment time and smile esthetics as more important were more likely to prefer CA, while those who prioritized finishing details and cost were more likely to choose BMB (p < 0.05).

Conclusions: Reasons related to comfort and quality of life during use were considered as more important by PP, while those related to the results and clinical performance of the appliances were considered as more relevant by orthodontists.

目的:探讨影响准患者(PP)和正畸医师对某一矫治器的偏好的原因。方法:对49名PP和51名正畸医师进行调查,了解他们对清洁矫正器(CA)、舌金属托槽(LMB)、多晶和单晶陶瓷托槽、颊金属托槽(BMB)的使用偏好。参与者对17个可能解释他们选择的原因的重要性进行了排序。确定了导致这些偏好的主要原因。采用非参数检验(Fisher精确检验、χ2检验和Mann-Whitney检验)和多变量分析(回归和判别分析)对资料进行评价(α = 0.05)。结果:CA和BMB分别是PP和正畸医师选择最多的矫治器。LMB是两组参与者中被拒绝最多的选项(p < 0.001)。疼痛/不适、微笑美学、整理细节和喂养/言语障碍的重要性率在PP和正畸医生之间差异最大(p < 0.0005)。判别分析显示,认为治疗时间和微笑美学更重要的个体更倾向于选择CA,而优先考虑完成细节和成本的个体更倾向于选择BMB (p < 0.05)。结论:PP认为与使用过程中的舒适性和生活质量相关的原因更为重要,而正畸医师认为与矫治器的效果和临床性能相关的原因更为重要。
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引用次数: 9
READER'S FORUM. 读者的论坛。
IF 1.9 3区 医学 Q1 Dentistry Pub Date : 2021-03-25 DOI: 10.4041/kjod.2021.51.2.75
Nalin Katkoria Priyanka, Sekar Santhosh Kumar, Shivangi Ramteke, Balasubramanian Madhan
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引用次数: 0
READER'S FORUM. 读者的论坛。
IF 1.9 3区 医学 Q1 Dentistry Pub Date : 2020-11-25 DOI: 10.4041/kjod.2020.50.6.361
Hyun-Joo Jeong
A1. Patients with skeletal III relationships show prominent mandibular prognathism and it may be accompanied by facial asymmetry, especially if one side shows condylar hyperplasia. In this study, mandibular symmetry plane inclination and maxillary canting showed the similar tendency due to compensatory maxillary growth according to mandibular growth. Our research showed that mandibular symmetry plane is more strongly correlated with the lip canting and skeletal III relationship may affect the conclusion.
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引用次数: 0
Part I. What drives Korean adults to seek orthodontic treatment: Reliability and validity of a measurement instrument for the perception of orthodontic treatment. 第一部分是什么驱使韩国成年人寻求正畸治疗:对正畸治疗感知的测量工具的信度和效度。
IF 1.9 3区 医学 Q1 Dentistry Pub Date : 2020-11-25 DOI: 10.4041/kjod.2020.50.6.363
Min-Hee Oh, Eun-A Kim, Ae-Hyun Park, MinSoo Kim, Jin-Hyoung Cho

Objective: To develop a standardized instrument to measure the level of cognition for orthodontic treatment in adults, and verify its reliability and validity for assessing perceptions of orthodontic treatment in adults.

Methods: A total of 406 adults aged 19-64 years were surveyed by an internet research system. A tool was developed through the instrument development and verification stages. The data were analyzed by correlation analysis, exploratory factor analysis, confirmatory factor analysis, and Cronbach's α test.

Results: The instrument consisted of 11 items covering four factors related to orthodontic treatment. Three items were related to general perception, four described the perception of the treatment for adults, two related to the treatment effects, and two related to the retention of orthodontic treatment. In the reliability test, Cronbach's α was 0.845 for the 11 items. In assessments for individual components, Cronbach's α was 0.764 for the general perception of orthodontic treatment, 0.705 for the perception of this treatment for adults, 0.707 for the effects of the treatment, and 0.701 for the retention of orthodontic treatment. Finally, a measurement instrument for the perception of orthodontic treatment in adults was designed to assess the 11 items on a four-point Likert scale.

Conclusions: This study developed a standard measurement instrument for assessing the perception of orthodontic treatment in adults. The proposed instrument will enable additional studies on the influence of an adult's perception of orthodontic treatment on the decision to undergo treatment.

目的:研制一种标准化的测量成人正畸治疗认知水平的仪器,并验证其用于评估成人正畸治疗认知的信度和效度。方法:采用网络调查系统对406名19 ~ 64岁的成年人进行调查。通过仪器开发和验证阶段开发了一个工具。采用相关分析、探索性因子分析、验证性因子分析和Cronbach’s α检验对数据进行分析。结果:该量表包含11个项目,涵盖正畸治疗相关的4个因素。3项与一般知觉有关,4项描述成人治疗的知觉,2项与治疗效果有关,2项与正畸治疗的保留有关。在信度检验中,11个条目的Cronbach’s α为0.845。在个体成分的评估中,正畸治疗的总体认知为0.764,成人正畸治疗的认知为0.705,治疗效果为0.707,正畸治疗的保留性为0.701。最后,设计了一种成人正畸治疗感知测量工具,以李克特四分制对11个项目进行评估。结论:本研究开发了一种标准的测量工具来评估成人正畸治疗的感知。拟议的仪器将能够进一步研究成人对正畸治疗的看法对接受治疗决定的影响。
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引用次数: 3
Innovative customized CAD/CAM nickel-titanium lingual retainer versus standard stainless-steel lingual retainer: A randomized controlled trial. 创新定制CAD/CAM镍钛舌保持器与标准不锈钢舌保持器:一项随机对照试验。
IF 1.9 3区 医学 Q1 Dentistry Pub Date : 2020-11-25 DOI: 10.4041/kjod.2020.50.6.373
Emilie Gelin, Laurence Seidel, Annick Bruwier, Adelin Albert, Carole Charavet

Objective: To compare computer-aided design and computer-aided manufacturing (CAD/CAM) customized nitinol retainers with standard stainlesssteel fixed retainers over a 12-month study period.

Methods: This randomized controlled trial (RCT) was conducted on 62 patients randomly allocated to a control group that received stainless-steel retainers or a test group that received customized CAD/CAM nickel-titanium retainers. Four time points were defined: retainer placement (T0) and 1-month (T1), 6-month (T2), and 12-month (T3) follow-up appointments. At each time point, Little's irregularity index (LII) (primary endpoint) and dental stability measurements such as intercanine width were recorded in addition to assessment of periodontal parameters. Radiological measurements such as the incisor mandibular plane angle (IMPA) were recorded at T0 and T3. Failure events (wire integrity or debonding) were assessed at each time point.

Results: From T0 to T3, LII and other dental measurements showed no significant differences between the two groups. The data for periodontal parameters remained stable over the study period, except for the gingival index, which was slightly, but significantly, higher in the test group at T3 (p = 0.039). The IMPA angle showed no intergroup difference. The two groups showed no significant difference in debonding events.

Conclusions: This RCT conducted over a 12-month period demonstrated no significant difference between customized CAD/CAM nickel-titanium lingual retainers and standard stainlesssteel lingual retainers in terms of dental anterior stability and retainer survival. Both retainers eventually appeared to be equally effective in maintaining periodontal health.

目的:在为期12个月的研究中,比较计算机辅助设计和计算机辅助制造(CAD/CAM)定制镍钛诺固位器与标准不锈钢固定固位器。方法:对62例患者进行随机对照试验(RCT),随机分为对照组使用不锈钢固位器组和试验组使用定制CAD/CAM镍钛固位器组。确定四个时间点:固位器放置(T0)和1个月(T1)、6个月(T2)和12个月(T3)随访。在每个时间点,除了评估牙周参数外,还记录Little's不规则指数(LII)(主要终点)和牙齿稳定性测量(如齿间宽度)。在T0和T3时记录门牙下颌平面角(IMPA)等放射学测量。在每个时间点评估失效事件(钢丝完整性或脱粘)。结果:T0 ~ T3时,两组间LII等牙体测量无明显差异。牙周参数的数据在研究期间保持稳定,除了牙龈指数,实验组在T3时略有升高,但显著升高(p = 0.039)。IMPA角度组间无差异。两组在脱粘事件上无显著差异。结论:这项为期12个月的随机对照试验显示,定制CAD/CAM镍钛舌固位器与标准不锈钢舌固位器在牙前稳定性和固位器存活方面无显著差异。两种固位器最终在维持牙周健康方面表现出同样的效果。
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引用次数: 15
Antifibrotic effects of sulforaphane treatment on gingival elasticity reduces orthodontic relapse after rotational tooth movement in beagle dogs. 萝卜硫素治疗对牙龈弹性的抗纤维化作用可减少比格犬旋转牙齿运动后正畸复发。
IF 1.9 3区 医学 Q1 Dentistry Pub Date : 2020-11-25 DOI: 10.4041/kjod.2020.50.6.391
Kyong-Nim Kim, Jue-Young Kim, Jung-Yul Cha, Sung-Hwan Choi, Jin Kim, Sung-Won Cho, Chung-Ju Hwang

Objective: Increased gingival elasticity has been implicated as the cause of relapse following orthodontic rotational tooth movement and approaches to reduce relapse are limited. This study aimed to investigate the effects of sulforaphane (SFN), an inhibitor of osteoclastogenesis, on gene expression in gingival fibroblasts and relapse after rotational tooth movement in beagle dogs.

Methods: The lower lateral incisors of five beagle dogs were rotated. SFN or dimethylsulfoxide (DMSO) were injected into the supra-alveolar gingiva of the experimental and control group, respectively, and the effect of SFN on relapse tendency was evaluated. Changes in mRNA expression of extracellular matrix components associated with gingival elasticity in beagles were investigated by real-time polymerase chain reaction. Morphology and arrangement of collagen fibers were observed on Masson's trichrome staining of buccal gingival tissues of experimental and control teeth.

Results: SFN reduced the amount and percentage of relapse of orthodontic rotation. It also decreased the gene expression of lysyl oxidase and increased the gene expression of matrix metalloproteinase (MMP) 1 and MMP 12, compared with DMSO control subjects. Histologically, collagen fiber bundles were arranged irregularly and were not well connected in the SFN-treated group, whereas the fibers extended in parallel and perpendicular directions toward the gingiva and alveolar bone in a more regular and well-ordered arrangement in the DMSO-treated group.

Conclusions: Our findings demonstrated that SFN treatment may be a promising pharmacologic approach to prevent orthodontic rotational relapse caused by increased gingival elasticity of rotated teeth in beagle dogs.

目的:牙龈弹性增加被认为是正畸旋转牙齿运动后复发的原因,减少复发的方法有限。本研究旨在探讨破骨细胞生成抑制剂萝卜硫素(SFN)对比格犬牙龈成纤维细胞基因表达和旋转牙齿运动后复发的影响。方法:旋转5只beagle犬的下侧切牙。实验组和对照组分别在牙槽上龈处注射SFN或二甲基亚砜(DMSO),观察SFN对复发倾向的影响。采用实时聚合酶链反应研究小猎犬牙龈弹性相关细胞外基质成分mRNA表达的变化。用马松三色染色法观察实验牙和对照牙颊龈组织胶原纤维的形态和排列。结果:SFN降低了正畸旋转的复发率和复发率。与DMSO对照组相比,赖氨酸氧化酶基因表达降低,基质金属蛋白酶(MMP) 1和MMP 12基因表达升高。组织学上,sfn处理组胶原纤维束排列不规则,连接不良好,而dmso处理组胶原纤维束向牙龈和牙槽骨平行和垂直方向延伸,排列更加规则和有序。结论:我们的研究结果表明,SFN治疗可能是一种很有希望的药物治疗方法,可以预防由于比格犬牙齿旋转后牙龈弹性增加而引起的正畸旋转复发。
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引用次数: 2
Comparison of slot sizes and parallelism of metal brackets manufactured through metal injection molding and computerized numerical control. 金属注射成型与计算机数控制造金属支架槽位尺寸及平行度的比较。
IF 1.9 3区 医学 Q1 Dentistry Pub Date : 2020-11-25 DOI: 10.4041/kjod.2020.50.6.401
Jae-Sung Park, In-Tae Song, Jae-Hee Bae, Soo-Min Gil, Kyung-Hwa Kang

Objective: To investigate and compare the slot sizes and parallelism of metal injection molding (MIM) and computerized numerical control (CNC) brackets.

Methods: The following four MIM bracket series with 0.022-inch (in) slots were selected for investigation: Di MIM mini Twin (Ortho Organizers), Mini Diamond Roth (Ormco), Gemini MBT (3M Unitek), and Formula R Roth (Tomy). The following four CNC bracket series with 0.022-in slots were selected for investigation: Econoline MBT (Adenta), Legend mini MBT (GC Orthodontics), Crown mini MBT (Adenta), and Evolve MBT (DB Orthodontics). The slot dimensions were measured using an optical microscope (XTCam-D310M; Mitutoyo) with a resolution of 1 μm. The results were statistically analyzed using one-way analysis of variance and the Tukey post-hoc test with a significance level of 0.05.

Results: The results indicated that all the investigated slot sizes were oversized with respect to the manufacturers' specifications (0.022 in). Among the eight bracket series, the Di MIM bracket (MIM) was the most oversized by 10.4%, whereas the Evolve bracket (CNC) was the least oversized by 2.6%. The slots in seven of the bracket series had divergent walls instead of parallel ones. The Evolve bracket alone had parallel slot walls.

Conclusions: Regardless of the manufacturing method, all the slot sizes of the brackets investigated in this study were significantly oversized; most of the slot walls were nonparallel, except for those of the Evolve bracket. This study could not establish that the CNC method was more accurate than the MIM method in manufacturing bracket slots.

目的:研究和比较金属注射成型(MIM)和计算机数控(CNC)支架的槽位尺寸和平行度。方法:选择0.022英寸(in)槽位MIM支架系列:Di MIM mini Twin (Ortho organizer)、mini Diamond Roth (Ormco)、Gemini MBT (3M Unitek)和Formula R Roth (Tomy)。选择4个0.022 in槽位的数控支架系列:Econoline MBT (Adenta)、Legend mini MBT (GC Orthodontics)、Crown mini MBT (Adenta)和Evolve MBT (DB Orthodontics)。采用光学显微镜(XTCam-D310M;Mitutoyo),分辨率为1 μm。结果采用单因素方差分析和Tukey事后检验进行统计学分析,显著性水平为0.05。结果:结果表明,所有调查的槽尺寸都超过了制造商的规格(0.022英寸)。在8个支架系列中,Di MIM支架(MIM)的尺寸最大,为10.4%,而Evolve支架(CNC)的尺寸最小,为2.6%。在支架系列中,有七个槽的壁是发散的,而不是平行的。仅Evolve支架就有平行槽壁。结论:无论制作方法如何,本研究中调查的所有托槽尺寸都显着过大;除了Evolve支架外,大多数槽壁都是非平行的。本研究不能证明CNC方法比MIM方法加工支架槽的精度更高。
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引用次数: 2
期刊
Korean Journal of Orthodontics
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