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Analysis and Categorization of Various Types of Vocal Distortion in Rock, Metal, Pop Styles, and Throat Singing Observed by High-Speed Digital Imaging. 高速数字成像对摇滚、金属、流行风格和喉音演唱中各种类型声音失真的分析和分类。
IF 2.5 4区 医学 Q1 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY Pub Date : 2025-01-08 DOI: 10.1016/j.jvoice.2024.11.041
Yogaku Lee, Masato Tanaka, Hikari Kato, Takashi Nakagawa, Satoshi Ishikawa, Tokihiko Kaburagi

Introduction: Vocal distortion, also known as a scream or growl, is used worldwide as an essential technique in singing, especially in rock and metal, and as an ethnic voice in Mongolian singing. However, the production mechanism of vocal distortion is not yet clearly understood owing to limited research on the behavior of the larynx, which is the source of the distorted voice.

Objectives: This study used high-speed digital imaging (HSDI) to observe the larynx of professional singers with exceptional singing skills and determine the laryngeal dynamics in the voice production of various vocal distortions. In addition, this study aimed to classify vocal distortions based on laryngeal dynamics.

Study design: Cross-sectional study.

Methods: The dynamic behavior of the larynx of six singers (four males and two females) was recorded using HSDI, with the majority of recordings captured at frame rates exceeding 8000 fps. The audio signals were recorded simultaneously. The data were analyzed as topography, glottal area waveforms, long-term average spectra, and spectrograms.

Results: Our analysis revealed that, based on the laryngeal vibration pattern, vocal distortion could be categorized into two primary groups: "periodic" and "aperiodic." In the "periodic" distorted vocalizations, it was suggested that the glottal sound source containing overtone components is generated by vocal fold vibrations, and subharmonic components in the voice are the result of amplitude modulation of the glottal jet by vibrations in the supraglottic region. However, "aperiodic" distorted vocalizations were found to be generated by the vocal folds, which are the main source of noise and generate strong noise due to aperiodic chaotic oscillations of the vocal folds.

Conclusion: The diversity of distorted vocalizations is due to the physiologically and acoustically complex mechanism of voice production in the larynx.

声音扭曲,也被称为尖叫或咆哮,在世界范围内被用作唱歌的基本技巧,特别是在摇滚和金属中,也是蒙古歌唱中的民族声音。然而,由于对喉部行为的研究有限,导致声音失真的产生机制尚不清楚。喉部是声音失真的来源。目的:本研究采用高速数字成像技术(HSDI)对具有特殊演唱技巧的专业歌手的喉部进行观察,确定各种声音失真在发声过程中的喉部动力学。此外,本研究的目的是根据喉部动力学对声音失真进行分类。研究设计:横断面研究。方法:采用HSDI对6名歌手(4男2女)的喉部动态行为进行记录,大多数录音的帧率超过8000fps。同时记录音频信号。数据分析为地形、声门面积波形、长期平均光谱和声谱图。结果:我们的分析显示,基于喉部振动模式,声音失真可以分为两大类:“周期性”和“非周期性”。在“周期性”畸变发声中,认为含有泛音成分的声门声源是由声带振动产生的,而声音中的次谐波成分是声门上区振动对声门射流调幅的结果。然而,我们发现声带会产生“非周期”畸变发声,这是噪声的主要来源,并且由于声带的非周期混沌振荡而产生强烈的噪声。结论:畸形发声的多样性是由于喉部产生声音的生理和声学复杂机制所致。
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引用次数: 0
Aerodynamic and Acoustic Power in Infant Cry. 婴儿哭声中的空气动力和声功率。
IF 2.5 4区 医学 Q1 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY Pub Date : 2025-01-08 DOI: 10.1016/j.jvoice.2024.12.033
Ingo R Titze

Objectives: Acoustic and aerodynamic powers in infant cry are not scaled downward with body size or vocal tract size. The objective here was to show that high lung pressures and impedance matching are used to produce power levels comparable to those in adults.

Study design and methodology: A computational model was used to obtain power distributions along the infant airway. The parameters were cross-sectional areas of the larynx canal and the velar region, which tend to be variable in infant cry when there is no specific vowel structure.

Results: Aerodynamic power can reach 1.0 W with 70 cm H2O lung pressure, while acoustic power radiated from the mouth reaches about 1.0 mW, corresponding to 90 dB sound level at 30 cm from the mouth. Acoustic evidence of potential roughness is introduced with a narrow larynx canal (epilaryngeal airway).

Conclusions: Infants are born with the ability to produce high lung pressures to compensate for reduced airflow in a small vocal tract. Airflow impedances are about 100 times higher than in adults. Maximum power transfer from the source to the airway (and ultimately to the listener) appears to be an innate ability.

目的:婴儿啼哭的声学和空气动力不随身体大小或声道大小而下降。这里的目的是证明高肺压和阻抗匹配可以产生与成人相当的功率水平。研究设计和方法:采用计算模型获得婴儿气道的功率分布。参数为喉道的横截面积和腭区,当婴儿哭声中没有特定的元音结构时,这两个参数往往是可变的。结果:在70 cm H2O肺压下,气动功率可达1.0 W,而口部辐射声功率约为1.0 mW,对应距离口部30 cm处的90 dB声级。声学证据的潜在粗糙度引入狭窄的喉管(后咽气道)。结论:婴儿天生具有产生高肺压的能力,以补偿小声道气流减少。气流阻抗大约是成人的100倍。从声源到气道(最终到听者)的最大功率传输似乎是一种天生的能力。
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引用次数: 0
An Electroglottographic and Acoustic Study on Mandarin Speech in Male Heroin Users. 男性海洛因使用者普通话言语的声门电图和声学研究。
IF 2.5 4区 医学 Q1 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY Pub Date : 2025-01-08 DOI: 10.1016/j.jvoice.2024.12.017
Puyang Geng, Ningxue Fan, Rong Ling, Zhijun Li, Hong Guo

Drug abuse can cause severe damage to the human speech organs. The vocal folds are one of the important speech organs that produce voice through vibration when airflow passes through. Previous studies have reported the negative effects of drugs on speech organs, including the vocal folds, but there is still limited research on relevant field. Therefore, the current study recruited 25 heroin users and 30 healthy controls with no history of drug use. Electroglottography and speech signals of 26 target sentences were collected from all participants. The results of the current study showed that the heroin group exhibited higher DFx1 and H1-A3, and lower DAx1 and jitter, and lower F1 frequency for /a/ and F2 frequency for /i/, but higher F2 frequency for /u/ compared to the no drug group. These findings suggested the presence of vocal hoarseness, frequency and amplitude distributions that differed from the norm, and a limited range of tongue movement in the heroin group. This study not only enhances the understanding of the effects of heroin on speech production but also has implications for detoxification treatment and speech rehabilitation for drug users.

滥用药物会对人的语言器官造成严重损害。声带是气流通过时通过振动产生声音的重要语言器官之一。以往的研究报道了药物对包括声带在内的语言器官的负面影响,但相关领域的研究仍然有限。因此,本研究招募了25名海洛因使用者和30名没有药物使用史的健康对照者。采集了26个目标句子的声门电信号和语音信号。本研究结果显示,与未用药组相比,海洛因组DFx1和H1-A3较高,DAx1和jitter较低,/a/的F1频率较低,/i/的F2频率较低,/u/的F2频率较高。这些发现表明,海洛因组存在声音嘶哑,频率和振幅分布与正常情况不同,舌头运动范围有限。本研究不仅加深了对海洛因对语言产生的影响的认识,而且对吸毒者的戒毒治疗和语言康复具有重要意义。
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引用次数: 0
Muslim Religious Officials Have Less Voice Training and Higher Rate of Voice Disorder Than Christian Religious Officials. 与基督教宗教官员相比,穆斯林宗教官员的声音训练较少,声音障碍率较高。
IF 2.5 4区 医学 Q1 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY Pub Date : 2025-01-08 DOI: 10.1016/j.jvoice.2024.03.014
Sibel Ozmen, Maral Yesilyurt, Kursat Yelken

Purpose: To compare the Voice Handicap Index-10 Scores, voice hygiene habits, and voice training of Christian and Muslim religious officials living in Turkiye.

Method: In this study, a mixed method, including quantitative and qualitative research, was used. The population of the research consists of Christian and Muslim religious officials working in Turkiye.

Sample: a total of 40 participants, including 20 Muslim religious officials, 15 imam-hatips, and 5 muezzin-trustees, determined by random sampling method, and 20 Christian religious officials, 15 priests and 5 ministers, determined by snowball sampling method were included.

Results: There was a statistically significant difference in the total scores of the Voice Handicap Index-10 scale between Muslim and Christian religious officials. There was no statistically significant difference between Muslim religious officials and Christian religious officials in terms of whether they had a voice disorder before starting their profession, Muslim religious officials had a significantly higher rate of voice disorders than Christian religious officials after they started their profession. It was observed that there was no statistically significant difference between Muslim religious officials and Christian religious officials in terms of daily water, tea, coffee, and tobacco use. All of the Christian religious officials and some of the Muslim religious officials have received musical education at some point in their lives.

Conclusion: On the basis of Voice Handicap Index-10 scores and voice hygiene habits evaluation, Muslim religious officials have higher rate of voice disorder than Christian religious officials. Regarding voice training evaluation, Muslim religious officials had less voice training, as they did not include voice and music education in their vocational education curriculum, while Christian religious officials received both.

目的:比较居住在土耳其的基督教和穆斯林宗教官员的声音障碍指数-10评分、声音卫生习惯和声音训练。方法:本研究采用定量与定性相结合的研究方法。研究对象包括在土耳其工作的基督教和穆斯林宗教官员。样本:共40人,其中穆斯林宗教官员20人,伊玛目-哈提普15人,宣礼员受托人5人,采用随机抽样法;基督教宗教官员20人,牧师15人,牧师5人,采用滚雪球抽样法。结果:穆斯林和基督教宗教官员在声音障碍指数-10量表的总分上有统计学差异。穆斯林宗教官员与基督教宗教官员在入职前是否有发声障碍方面差异无统计学意义,穆斯林宗教官员入职后出现发声障碍的比例明显高于基督教宗教官员。据观察,穆斯林宗教官员和基督教宗教官员在日常用水、茶、咖啡和烟草使用方面没有统计学上的显著差异。所有的基督教宗教官员和一些穆斯林宗教官员在他们生命中的某个阶段都接受过音乐教育。结论:基于声音障碍指数-10评分和声音卫生习惯评价,穆斯林宗教官员的声音障碍率高于基督教宗教官员。在声音训练评估方面,穆斯林宗教官员的声音训练较少,因为他们的职业教育课程中没有包括声音和音乐教育,而基督教宗教官员则同时接受声音和音乐教育。
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引用次数: 0
Vocal Instabilities in Untrained Female Singers. 未经训练的女歌手的声音不稳定。
IF 2.5 4区 医学 Q1 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY Pub Date : 2025-01-07 DOI: 10.1016/j.jvoice.2024.12.038
Michelle M Bretl, Ronald C Scherer

Objectives: This study aimed to identify voice instabilities across registration shifts produced by untrained female singers and describe them relative to changes in fundamental frequency, airflow, intensity, inferred adduction, and acoustic spectra.

Study design: Multisignal descriptive study.

Methods: Five untrained female singers sang up to 30 repetitions of octave scales. They first produced these octave scales "naturally," followed by productions that were either deliberately smooth or deliberately unsteady. With all types of scale productions, participants sang with both /α/ and /i/ vowels, at two different dynamic levels, and across both the upper and lower predetermined register transitions. Recorded scales were categorized into three groups (Smooth, Middle, Unsteady) based on researcher-based perceptual smoothness of the auditory signals. These groups allowed for determination of salient features of unsteadiness based on observations and analyses of the acoustic, airflow, intensity, and electroglottography (EGG) waveforms.

Results: A total of 13 different types of instabilities were observed. The number of instabilities within a single scale ranged from zero to fourteen. Most Smooth scales had zero to three instabilities, most Middle scales had four to six, and most Unsteady scales had six or more instabilities within the scale. More obvious instabilities, such as aphonic segments, were present only in Unsteady scales, while more subtle instabilities, such as those related to EGG signal changes, were common in all scale categories, including Smooth scales.

Conclusions: This study revealed that untrained singers can sing smoothly throughout octave scales, and the primary unsteadiness variable was an aphonic segment and corresponding abrupt and large intensity reduction. Particular instabilities may be related to subtle aspects of register change and vocal control. Some objective measures appear to be more visually and numerically salient than auditorily perceived events relative to unsteadiness in the production of scales.

目的:本研究旨在识别未经训练的女歌手在注册变化中产生的声音不稳定性,并将其与基频、气流、强度、推断内收和声学光谱的变化相关联。研究设计:多信号描述性研究。方法:五名未经训练的女歌手演唱多达30个重复的八度音阶。他们首先“自然地”制造出这些八度音阶,然后故意制造出平滑或不稳定的音阶。在所有类型的音阶作品中,参与者在两个不同的动态水平上演唱/α/和/i/元音,并在上下预定音域过渡中演唱。根据研究者对听觉信号的感知平滑度,将记录的量表分为平滑、中等和不稳定三组。这些组可以根据声学、气流、强度和声门电图(EGG)波形的观察和分析来确定不稳定的显著特征。结果:共观察到13种不同类型的不稳定性。单一尺度内不稳定性的数量从0到14不等。大多数平滑量表有0到3个不稳定性,大多数中等量表有4到6个不稳定性,大多数非稳定量表有6个或更多的不稳定性。更明显的不稳定性,如语音片段,只存在于非定常音阶中,而更微妙的不稳定性,如与EGG信号变化有关的不稳定性,在所有音阶类别中都很常见,包括平滑音阶。结论:本研究表明,未经训练的歌唱者可以在整个八度音阶上流畅地演唱,主要的不稳定变量是一个音段和相应的突然而大的强度下降。特殊的不稳定性可能与音域变化和声音控制的微妙方面有关。一些客观测量在视觉上和数字上似乎比听觉上感知到的事件更突出,这与生产尺度的不稳定性有关。
{"title":"Vocal Instabilities in Untrained Female Singers.","authors":"Michelle M Bretl, Ronald C Scherer","doi":"10.1016/j.jvoice.2024.12.038","DOIUrl":"https://doi.org/10.1016/j.jvoice.2024.12.038","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to identify voice instabilities across registration shifts produced by untrained female singers and describe them relative to changes in fundamental frequency, airflow, intensity, inferred adduction, and acoustic spectra.</p><p><strong>Study design: </strong>Multisignal descriptive study.</p><p><strong>Methods: </strong>Five untrained female singers sang up to 30 repetitions of octave scales. They first produced these octave scales \"naturally,\" followed by productions that were either deliberately smooth or deliberately unsteady. With all types of scale productions, participants sang with both /α/ and /i/ vowels, at two different dynamic levels, and across both the upper and lower predetermined register transitions. Recorded scales were categorized into three groups (Smooth, Middle, Unsteady) based on researcher-based perceptual smoothness of the auditory signals. These groups allowed for determination of salient features of unsteadiness based on observations and analyses of the acoustic, airflow, intensity, and electroglottography (EGG) waveforms.</p><p><strong>Results: </strong>A total of 13 different types of instabilities were observed. The number of instabilities within a single scale ranged from zero to fourteen. Most Smooth scales had zero to three instabilities, most Middle scales had four to six, and most Unsteady scales had six or more instabilities within the scale. More obvious instabilities, such as aphonic segments, were present only in Unsteady scales, while more subtle instabilities, such as those related to EGG signal changes, were common in all scale categories, including Smooth scales.</p><p><strong>Conclusions: </strong>This study revealed that untrained singers can sing smoothly throughout octave scales, and the primary unsteadiness variable was an aphonic segment and corresponding abrupt and large intensity reduction. Particular instabilities may be related to subtle aspects of register change and vocal control. Some objective measures appear to be more visually and numerically salient than auditorily perceived events relative to unsteadiness in the production of scales.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142957895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Machine Learning Models With Hyperparameter Optimization for Voice Pathology Classification on Saarbrücken Voice Database. 基于saarbr<s:1> cken语音数据库的语音病理分类超参数优化机器学习模型。
IF 2.5 4区 医学 Q1 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY Pub Date : 2025-01-07 DOI: 10.1016/j.jvoice.2024.12.009
Pervin Gulsen, Abdulkadir Gulsen, Mustafa Alci

Early diagnosis and referral are crucial in the treatment of voice disorders. Contemporary investigations have indicated the efficacy of voice pathology detection systems in significantly contributing to the evaluation of voice disorders, facilitating early diagnosis of such pathologies. These systems leverage machine learning methodologies, widely applied across diverse domains, and exhibit particular potential in the realm of voice pathology classification. However, machine learning models and performance metrics employed in these studies vary significantly, making it challenging to determine the optimal model for voice pathology classification. In this study, healthy and pathological voices were classified with state-of-the-art machine learning models, and the performance results of the models were compared. The voice samples employed in our research were sourced from the Saarbrücken Voice Database, a reputable German database. Feature extraction from voice signals was conducted using the Mel Frequency Cepstral Coefficients method. To assess and enhance the models' performance adequately, we employed hyperparameter optimization and implemented a 10-fold cross-validation approach. The outcomes revealed that the support vector machine model exhibited the highest accuracy, achieving 99.19% and 99.50% accuracies in the classification of male and female voice pathologies, respectively.

早期诊断和转诊对嗓音障碍的治疗至关重要。当前的研究表明,语音病理检测系统在评估语音障碍、促进此类病理的早期诊断方面具有重要作用。这些系统利用机器学习方法,广泛应用于各个领域,并在语音病理分类领域表现出特别的潜力。然而,这些研究中使用的机器学习模型和性能指标差异很大,这使得确定语音病理分类的最佳模型具有挑战性。在本研究中,使用最先进的机器学习模型对健康和病理声音进行分类,并比较模型的性能结果。在我们的研究中使用的声音样本来自saarbr cken声音数据库,一个著名的德国数据库。采用Mel频率倒谱系数法对语音信号进行特征提取。为了充分评估和增强模型的性能,我们采用了超参数优化并实施了10倍交叉验证方法。结果表明,支持向量机模型在男声和女声病理分类中准确率最高,分别达到99.19%和99.50%。
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引用次数: 0
Techniques, Models, and Variables of Interest in Studies of Intrinsic Laryngeal Muscle Fiber Types: A Bibliometric Analysis. 喉内肌纤维类型研究中的技术、模型和变量:文献计量学分析。
IF 2.5 4区 医学 Q1 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY Pub Date : 2025-01-04 DOI: 10.1016/j.jvoice.2024.12.018
Christopher S Apfelbach, Lady Catherine Cantor-Cutiva, Adrián Castillo-Allendes, Eric J Hunter

Introduction: Laryngeal muscle physiology is integral to many speech, voice, swallowing, and respiratory functions. A key determinant of a muscle's contractile properties, including its fatigue profile and capacity for force production, is the myosin heavy chain (MyHC) isoform that predominates in the muscle. This study surveys literature on the MyHC compositions of mammalian intrinsic laryngeal skeletal muscle to illustrate trends and gaps in laryngeal muscle fiber typing techniques, models, and concepts.

Methods: The Embase, Scopus, Medline, Web of Science, and Cochrane databases were systematically searched for studies of mammalian intrinsic laryngeal muscle MyHC composition. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for systematic reviews, 1531 non-duplicate papers were identified; 146 were selected for full-text screening. One hundred twenty papers were included in the final bibliometric analysis, which aimed to highlight key concepts in the literature.

Results: Publication of intrinsic laryngeal MyHC studies peaked in the early 2000s and has since declined. Although early research predominantly used histochemical techniques and large mammalian models (cow, sheep, dog, horse, etc), practice has evolved to focus on electrophoretic, immunohistochemical, and transcriptomic fiber typing techniques in rats and humans. Comparatively few studies have examined how experimental manipulations affect laryngeal muscle MyHC composition.

Discussion: Three areas of laryngeal muscle physiology lack a large body of supporting literature: (1) MyHC responses to stimuli such as training and disease, (2) MyHC plasticity across the lifespan, and (3) MyHC heterogeneity within muscle fibers (MyHC polymorphisms) and across muscle fibers (topographical MyHC distribution). We propose new avenues for research, education, and discussion in these three subdomains.

喉部肌肉的生理机能是许多语言、声音、吞咽和呼吸功能的组成部分。肌肉收缩特性的关键决定因素,包括其疲劳特征和力量产生能力,是肌球蛋白重链(MyHC)同种异构体,在肌肉中占主导地位。本研究调查了有关哺乳动物喉内骨骼肌MyHC组成的文献,以说明喉肌纤维分型技术、模型和概念的趋势和差距。方法:系统检索Embase、Scopus、Medline、Web of Science、Cochrane等数据库,检索哺乳动物喉内肌MyHC组成的相关研究。根据系统评价的首选报告项目和荟萃分析(PRISMA)指南,确定了1531篇非重复论文;选取146份进行全文筛选。120篇论文被纳入最后的文献计量学分析,其目的是突出文献中的关键概念。结果:喉部MyHC研究的发表在21世纪初达到顶峰,此后开始下降。虽然早期的研究主要使用组织化学技术和大型哺乳动物模型(牛、羊、狗、马等),但实践已经发展到专注于大鼠和人类的电泳、免疫组织化学和转录组纤维分型技术。相对较少的研究考察了实验操作如何影响喉肌MyHC组成。讨论:喉肌生理学的三个领域缺乏大量的支持文献:(1)MyHC对训练和疾病等刺激的反应,(2)MyHC在整个生命周期中的可塑性,以及(3)肌纤维内MyHC的异质性(MyHC多态性)和跨肌纤维(MyHC的地形分布)。我们为这三个子领域的研究、教育和讨论提出了新的途径。
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引用次数: 0
Cepstral Peak Prominence: A Valuable Measure of Voice Outcome Severity in Patients With Unilateral Vocal Fold Paralysis. 背侧峰突出:单侧声带麻痹患者声音结果严重程度的一个有价值的测量。
IF 2.5 4区 医学 Q1 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY Pub Date : 2025-01-04 DOI: 10.1016/j.jvoice.2024.11.031
Jing-Yi Jiang, Pei-Min Hsu, Yi-An Pan, Yi-Hsuan Yu, Chin-Kuo Chen, Li-Chun Hsieh

Objectives: This study investigated the relationship between the position of the paralyzed vocal fold and voice quality in patients with unilateral vocal fold paralysis (UVFP) and identified a reliable acoustic analysis tool to enhance the accuracy of voice quality assessments in this population.

Methods: A retrospective case-control study was conducted with 70 patients with UVFP diagnosed at Mackay Memorial Hospital. Acoustic features-jitter, shimmer, the harmonic-to-noise ratio (HNR), and the cepstral peak prominence smoothed (CPPs)-were analyzed using the Praat software. A speech-language pathologist performed an auditory-perceptual assessment by using a perceptual voice evaluation scale, and a senior laryngologist reviewed the paralyzed fold's position endoscopically. Spearman's linear regression analysis was used to examine correlations between perceptual and acoustic parameters and the position of the paralyzed vocal fold.

Results: The position of the paralyzed vocal fold exhibited weak correlations with acoustic and auditory-perceptual variables (r = 0.205-0.39). By contrast, moderate-to-strong correlations were discovered between auditory-perceptual variables and acoustic parameters (r = 0.378-0.803). Notably, the CPPs was more strongly associated with overall grade (severity: r = 0.673) and breathiness (r = -0.803) than with jitter, shimmer, and the HNR (r = 0.378-0.614).

Conclusions: The position of the paralyzed vocal fold alone is insufficient for predicting voice outcomes in patients with UVFP. The CPPs is a more valuable indicator of perceived dysphonia severity, particularly in cases with audible breathiness, making it superior to jitter, shimmer, and the HNR for perceptual voice assessments in patients with UVFP.

目的:本研究探讨单侧声带麻痹(UVFP)患者声带麻痹位置与语音质量之间的关系,并确定一种可靠的声学分析工具,以提高该人群语音质量评估的准确性。方法:对70例在麦凯纪念医院确诊的UVFP患者进行回顾性病例对照研究。使用Praat软件分析了声学特征-抖动、闪烁、谐波噪声比(HNR)和倒谱峰突出平滑(CPPs)。一位语言病理学家通过使用感知声音评估量表进行了听觉感知评估,一位高级喉科医生在内窥镜下检查了瘫痪襞的位置。使用Spearman线性回归分析来检查知觉和声学参数与瘫痪声带位置之间的相关性。结果:声带麻痹的位置与声学和听觉感知变量呈弱相关(r = 0.205 ~ 0.39)。相比之下,在听觉感知变量和声学参数之间发现了中等到强的相关性(r = 0.378-0.803)。值得注意的是,CPPs与总体评分(严重程度:r = 0.673)和呼吸(r = -0.803)的相关性比与抖动、闪烁和HNR (r = 0.378-0.614)的相关性更强。结论:单纯的声带麻痹位置不足以预测UVFP患者的声音预后。CPPs是感知语音障碍严重程度的更有价值的指标,特别是在可听到呼吸的情况下,使其优于UVFP患者的感知语音评估的抖动,闪烁和HNR。
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引用次数: 0
Anatomical Study of the Larynx With Implications for Medialization Thyroplasty. 喉的解剖研究及其对甲状腺成形术的影响。
IF 2.5 4区 医学 Q1 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY Pub Date : 2025-01-03 DOI: 10.1016/j.jvoice.2024.11.038
Isabel López-Sánchez, Ainhoa García-Lliberós, Rosa Hernández-Sandemetrio, Natsuki Oishi, Enrique Zapater

Objetives: Montgomery medialization thyroplasty involves fitting a silicone prosthesis in the thyroid cartilage according to gender-based placement criteria. This standardized procedure can lead in some cases to suboptimal results. The aim of this study is to identify individual anatomical differences between same-gender patients that could explain the occasional failures.

Methods: A prospective anatomical study was performed using 28 human laryngeal specimens (14 male, 14 female) obtained by clinical necropsy. Different measures on the thyroid ala were taken in order to describe the morphology of the thyroid cartilage and the location of the vocal fold: the distance between the superior thyroid notch and the inferior thyroid border (A), the distance between inferior thyroid border and inferior tubercle of the thyroid cartilage (B), the projection of the vocal fold into the thyroid ala including the distance between the anterior commissure and the inferior border of the thyroid cartilage (D1), and the distance between the projection of the vocal process of the arytenoid and the laryngeal tubercle (D2). Statistical analysis was performed to determine the relationship between gender and the mentioned measurements. A P value of 0.05 was considered statistically significant.

Results: High rates of interindividual anatomical variability were observed irrespective of gender. In male samples, measurements A, B, D1, and D2 varied up to 5, 10, 8, and 8 mm respectively. Variability was even more evident in female larynges which varied up to 11, 7, 8, and 9 mm, respectively. The results of the measurements were similar between male and female.

Conclusion: Montgomery thyroplasty failures can be due to individual anatomical variations regardless of gender. Based on our results, there is a significant interindividual anatomical variability irrespective of gender, even more evident among women. Customizing the location of the prosthesis may be an efficient way to solve this difficulty.

目的:蒙哥马利中间化甲状腺成形术包括根据性别放置标准在甲状腺软骨中安装硅胶假体。这种标准化的程序在某些情况下可能导致次优结果。这项研究的目的是确定同性患者之间的个体解剖差异,这可以解释偶尔的失败。方法:对临床尸检获得的28例喉部标本(男14例,女14例)进行前瞻性解剖学研究。为了描述甲状软骨的形态和声带的位置,对甲状软骨采取了不同的测量方法:甲状上切迹到甲状下缘的距离(A),甲状下缘到甲状软骨下结节的距离(B),声带到甲状翼的投影,包括前连合到甲状软骨下缘的距离(D1),类喉突发声突投影到喉结节的距离(D2)。通过统计分析确定性别与上述测量值之间的关系。P值为0.05认为有统计学意义。结果:无论性别,个体间的解剖变异率都很高。在男性样本中,测量值A、B、D1和D2分别变化高达5、10、8和8毫米。女性喉部的差异更为明显,分别可达11、7、8和9毫米。测量结果在男性和女性之间是相似的。结论:蒙哥马利甲状腺成形术的失败可能是由于个体解剖结构的差异,而与性别无关。根据我们的研究结果,存在显著的个体间解剖差异,与性别无关,在女性中更为明显。定制假体的位置可能是解决这一困难的有效方法。
{"title":"Anatomical Study of the Larynx With Implications for Medialization Thyroplasty.","authors":"Isabel López-Sánchez, Ainhoa García-Lliberós, Rosa Hernández-Sandemetrio, Natsuki Oishi, Enrique Zapater","doi":"10.1016/j.jvoice.2024.11.038","DOIUrl":"https://doi.org/10.1016/j.jvoice.2024.11.038","url":null,"abstract":"<p><strong>Objetives: </strong>Montgomery medialization thyroplasty involves fitting a silicone prosthesis in the thyroid cartilage according to gender-based placement criteria. This standardized procedure can lead in some cases to suboptimal results. The aim of this study is to identify individual anatomical differences between same-gender patients that could explain the occasional failures.</p><p><strong>Methods: </strong>A prospective anatomical study was performed using 28 human laryngeal specimens (14 male, 14 female) obtained by clinical necropsy. Different measures on the thyroid ala were taken in order to describe the morphology of the thyroid cartilage and the location of the vocal fold: the distance between the superior thyroid notch and the inferior thyroid border (A), the distance between inferior thyroid border and inferior tubercle of the thyroid cartilage (B), the projection of the vocal fold into the thyroid ala including the distance between the anterior commissure and the inferior border of the thyroid cartilage (D1), and the distance between the projection of the vocal process of the arytenoid and the laryngeal tubercle (D2). Statistical analysis was performed to determine the relationship between gender and the mentioned measurements. A P value of 0.05 was considered statistically significant.</p><p><strong>Results: </strong>High rates of interindividual anatomical variability were observed irrespective of gender. In male samples, measurements A, B, D1, and D2 varied up to 5, 10, 8, and 8 mm respectively. Variability was even more evident in female larynges which varied up to 11, 7, 8, and 9 mm, respectively. The results of the measurements were similar between male and female.</p><p><strong>Conclusion: </strong>Montgomery thyroplasty failures can be due to individual anatomical variations regardless of gender. Based on our results, there is a significant interindividual anatomical variability irrespective of gender, even more evident among women. Customizing the location of the prosthesis may be an efficient way to solve this difficulty.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amniotic Fluid as a Potential Treatment for Vocal Fold Scar in a Rabbit Model. 羊水作为兔模型声带瘢痕的潜在治疗方法。
IF 2.5 4区 医学 Q1 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY Pub Date : 2025-01-03 DOI: 10.1016/j.jvoice.2024.12.015
Jenny L Pierce, Brendan Olson, Ray M Merrill, Jan Pierce, Anika Isom, Vanessa Torrecillas, Hilary McCrary, Alana Aylward, Marshall E Smith, M Ben Christensen

Objectives/hypothesis: Vocal fold (VF) injury and chronic inflammation can progress to scarring, which is notoriously difficult to treat. Human amniotic fluid (AF) has potential for VF wound healing in a rabbit model, and we hypothesized that AF would demonstrate wound healing properties superior to hyaluronic acid (HA) over time.

Study design: Randomized, controlled trial.

Methods: In this pilot study, 60 New Zealand white rabbits (10 rabbits in each of six groups) received unilateral VF biopsy and immediate injection treatment of AF, HA, or saline (SA). The contralateral VF served as an uninjured control. Rabbits were sacrificed and VFs removed at 4 or 10 weeks postinjury. Rheology and reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR) were employed to assess viscoelastic properties and inflammation, respectively.

Results: Rheology differences were seen between four and 10 weeks postinjury in treatment groups but not in controls. Values for the AF treatment group differed from the SA and HA groups at week 10 (elastic P = 0.0002, viscous P < 0.0001). RT-qPCR: AF and HA had higher levels of inflammatory cytokines than SA at week 4 [TNFα: SA4 < HA4 (P = 0.0086), SA4 < AF4 (P = 0.0112)]. Presumptive inflammation was still present at 10 weeks in all treatment groups [IL-1β: AF control < AF (P = 0.0002), SA control < SA (P = 0.0212); IL-6: HA control < HA (P = 0.0312)]. AF demonstrated reduced inflammation at 10 weeks compared with SA [IL-6: SA > AF (P = 0.0141)]. AF was the only treatment group that had significant reductions in inflammation at 10 versus 4 weeks [IL-1β: AF4 > AF10 (P = 0.0249)].

Conclusions: The main finding from this pilot study was that AF demonstrated wound healing effects over time compared with HA and SA by reducing inflammation and improving VF viscoelastic properties. Continued research to further investigate the use of AF in VF wound healing over longer periods of time is necessary before translation to human VFs.

目的/假设:声带(VF)损伤和慢性炎症可发展为瘢痕,这是众所周知的难以治疗。在兔模型中,人羊水(AF)具有潜在的VF伤口愈合作用,我们假设随着时间的推移,AF将表现出优于透明质酸(HA)的伤口愈合特性。研究设计:随机对照试验。方法:在这项初步研究中,60只新西兰大白兔(6组每组10只)接受单侧VF活检,并立即注射房颤、HA或生理盐水(SA)。对侧VF作为未损伤对照。在损伤后4周或10周处死家兔,摘除VFs。采用流变学和逆转录定量实时聚合酶链反应(RT-qPCR)分别评估粘弹性和炎症。结果:损伤后4周和10周,治疗组的流变学有差异,而对照组无差异。第10周AF治疗组与SA和HA组的数值不同(弹性P = 0.0002,粘性P = 0.0141)。AF是唯一在第10周与第4周相比炎症显著减少的治疗组[IL-1β: AF4 > AF10 (P = 0.0249)]。结论:这项初步研究的主要发现是,与HA和SA相比,随着时间的推移,AF通过减少炎症和改善VF粘弹性来显示伤口愈合效果。在转化为人类VFs之前,有必要在更长的时间内进一步研究AF在VF伤口愈合中的应用。
{"title":"Amniotic Fluid as a Potential Treatment for Vocal Fold Scar in a Rabbit Model.","authors":"Jenny L Pierce, Brendan Olson, Ray M Merrill, Jan Pierce, Anika Isom, Vanessa Torrecillas, Hilary McCrary, Alana Aylward, Marshall E Smith, M Ben Christensen","doi":"10.1016/j.jvoice.2024.12.015","DOIUrl":"https://doi.org/10.1016/j.jvoice.2024.12.015","url":null,"abstract":"<p><strong>Objectives/hypothesis: </strong>Vocal fold (VF) injury and chronic inflammation can progress to scarring, which is notoriously difficult to treat. Human amniotic fluid (AF) has potential for VF wound healing in a rabbit model, and we hypothesized that AF would demonstrate wound healing properties superior to hyaluronic acid (HA) over time.</p><p><strong>Study design: </strong>Randomized, controlled trial.</p><p><strong>Methods: </strong>In this pilot study, 60 New Zealand white rabbits (10 rabbits in each of six groups) received unilateral VF biopsy and immediate injection treatment of AF, HA, or saline (SA). The contralateral VF served as an uninjured control. Rabbits were sacrificed and VFs removed at 4 or 10 weeks postinjury. Rheology and reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR) were employed to assess viscoelastic properties and inflammation, respectively.</p><p><strong>Results: </strong>Rheology differences were seen between four and 10 weeks postinjury in treatment groups but not in controls. Values for the AF treatment group differed from the SA and HA groups at week 10 (elastic P = 0.0002, viscous P < 0.0001). RT-qPCR: AF and HA had higher levels of inflammatory cytokines than SA at week 4 [TNFα: SA4 < HA4 (P = 0.0086), SA4 < AF4 (P = 0.0112)]. Presumptive inflammation was still present at 10 weeks in all treatment groups [IL-1β: AF control < AF (P = 0.0002), SA control < SA (P = 0.0212); IL-6: HA control < HA (P = 0.0312)]. AF demonstrated reduced inflammation at 10 weeks compared with SA [IL-6: SA > AF (P = 0.0141)]. AF was the only treatment group that had significant reductions in inflammation at 10 versus 4 weeks [IL-1β: AF4 > AF10 (P = 0.0249)].</p><p><strong>Conclusions: </strong>The main finding from this pilot study was that AF demonstrated wound healing effects over time compared with HA and SA by reducing inflammation and improving VF viscoelastic properties. Continued research to further investigate the use of AF in VF wound healing over longer periods of time is necessary before translation to human VFs.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of Voice
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