Pub Date : 2026-01-01DOI: 10.1016/j.jvoice.2023.08.007
Daniel A. Alfonso-Ying , Christine M. Clark , Theresa Scognamiglio , Hal Rives , Lucian Sulica
Objectives/Hypothesis
Cysts are benign vocal fold lesions typically divided into mucous retention or epidermoid subtypes. The conventional paradigm that the former are translucent and the latter opaque fails to encompass the heterogeneity of cyst appearance on laryngoscopy. This study aims to characterize the relationships between clinical cyst characteristics and histopathology.
Study Design
Retrospective cohort
Methods
Clinicodemographic data, videostroboscopy findings, and histopathology results were retrospectively reviewed for adults who underwent surgical excision of vocal fold cysts at our institution between 2006 and 2021.
Results
Diagnostic histopathologic material was available for 69 patients (age: 50.4 ± 15.1 years, 68.1% female). Clinically, most cysts were opaque (69.6%) and located at the vibratory margin (82.6%). 11.6% were infraglottic. Significant associations existed between cyst location and epithelial type, with infraglottic cysts and those at the superior surface more commonly exhibiting ductal (P = 0.003) and squamous (P = 0.002) epithelium, respectively. Cyst opacity did not correlate with histopathology (P = 0.415). Epidermoid cysts were more likely to exhibit clinical inflammation (P = 0.002).
Conclusions
• Vocal fold cyst location, but not clinical appearance, appears to correlate with histopathology.
• Clinical signs of inflammation are significantly more common with epidermoid cysts.
{"title":"Correlation Between Laryngoscopic Appearance and Histopathology in Vocal Fold Cysts","authors":"Daniel A. Alfonso-Ying , Christine M. Clark , Theresa Scognamiglio , Hal Rives , Lucian Sulica","doi":"10.1016/j.jvoice.2023.08.007","DOIUrl":"10.1016/j.jvoice.2023.08.007","url":null,"abstract":"<div><h3>Objectives/Hypothesis</h3><div><span>Cysts are benign vocal fold<span> lesions typically divided into mucous retention or epidermoid subtypes. The conventional paradigm that the former are translucent and the latter opaque fails to encompass the heterogeneity of cyst appearance on laryngoscopy. This study aims to characterize the relationships between clinical cyst characteristics and </span></span>histopathology.</div></div><div><h3>Study Design</h3><div>Retrospective cohort</div></div><div><h3>Methods</h3><div>Clinicodemographic data, videostroboscopy findings, and histopathology results were retrospectively reviewed for adults who underwent surgical excision of vocal fold cysts at our institution between 2006 and 2021.</div></div><div><h3>Results</h3><div>Diagnostic histopathologic material was available for 69 patients (age: 50.4 ± 15.1 years, 68.1% female). Clinically, most cysts were opaque (69.6%) and located at the vibratory margin (82.6%). 11.6% were infraglottic. Significant associations existed between cyst location and epithelial type, with infraglottic cysts and those at the superior surface more commonly exhibiting ductal (<em>P</em> = 0.003) and squamous (<em>P</em> = 0.002) epithelium, respectively. Cyst opacity did not correlate with histopathology (<em>P</em><span> = 0.415). Epidermoid cysts were more likely to exhibit clinical inflammation (</span><em>P</em> = 0.002).</div></div><div><h3>Conclusions</h3><div><ul><li><span></span><span><div>• Vocal fold cyst location, but not clinical appearance, appears to correlate with histopathology.</div></span></li></ul><ul><li><span></span><span><div>• Clinical signs of inflammation are significantly more common with epidermoid cysts.</div></span></li></ul></div></div>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":"40 1","pages":"Pages 31-37"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10202591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.jvoice.2023.07.021
Nupur Kapoor Nerurkar, Zainab Nagree
Background
The objective is to study vocal outcomes following laser-assisted sulcus release (LASR), having documented the length and depth of the sulcus intraoperatively. LASR performed for superficial and deep sulci were included.
Study Design
Retrospective, observational.
Methods
The preoperative and 3-month postoperative and post voice-therapy Voice Handicap Index 10 (VHI), Grade-Roughness-Breathiness-Asthenia-Strain of the voice (GRBAS), Maximum Phonation Time (MPT), Fundamental Frequency (FO), and stroboscopy findings were noted retrospectively from our voice clinic records of LASR patients. Intraoperative sulci length and depth details were noted from records. Patients with coexisting lesions, surgically tackled, were excluded.
Results
In a total of 14 patients, 21 superficial sulci and eight deep sulci were operated by LASR. The average preoperative VHI improved from 25.3 to 9.9, GRBAS from 10.6 to 3.5, and MPT from 7.6 to 12.3 seconds. The preoperative average FO was 235.9 Hz in 12 patients (no pick-up in two) with a postoperative 248.4 Hz. Using the Mann-Whitney U test, we found a statistically significant improvement in MPT, VHI, and GRBAS of the patients. There was no significant improvement in the FO of the patients. There was no postoperative voice deterioration in any patient. A preoperative phonatory gap was found in all patients, which postoperatively was absent in 10, markedly decreased in three, present in one with stroboscopy revealing an improvement in mucosal wave amplitude in 13 patients. In four patients with deep bilateral sulci where the LASR had been ligament deep, VHI improved from 26 to 13.3, GRBAS from 12 to 6.5, and MPT from 4.3 to 9.5 seconds. Using the Mann-Whitney U test, all three parameters were significantly improved.
Conclusion
A statistically significant vocal improvement in VHI, GRBAS, and MPT was observed at 3 months, in superficial and deep sulci, operated by LASR. LASR is a simple, quick, and easily replicable surgery. Larger multi-centric studies with long-term follow-up are recommended.
{"title":"Vocal Outcomes Following Laser-Assisted Sulcus Release for Superficial and Deep Vocal Fold Sulcus","authors":"Nupur Kapoor Nerurkar, Zainab Nagree","doi":"10.1016/j.jvoice.2023.07.021","DOIUrl":"10.1016/j.jvoice.2023.07.021","url":null,"abstract":"<div><h3>Background</h3><div>The objective is to study vocal outcomes following laser-assisted sulcus release (LASR), having documented the length and depth of the sulcus intraoperatively. LASR performed for superficial and deep sulci were included.</div></div><div><h3>Study Design</h3><div>Retrospective, observational.</div></div><div><h3>Methods</h3><div>The preoperative and 3-month postoperative and post voice-therapy Voice Handicap Index 10 (VHI), Grade-Roughness-Breathiness-Asthenia-Strain of the voice (GRBAS), Maximum Phonation Time (MPT), Fundamental Frequency (FO), and stroboscopy findings were noted retrospectively from our voice clinic records of LASR patients. Intraoperative sulci length and depth details were noted from records. Patients with coexisting lesions, surgically tackled, were excluded.</div></div><div><h3>Results</h3><div>In a total of 14 patients, 21 superficial sulci and eight deep sulci were operated by LASR. The average preoperative VHI improved from 25.3 to 9.9, GRBAS from 10.6 to 3.5, and MPT from 7.6 to 12.3 seconds. The preoperative average FO was 235.9 Hz in 12 patients (no pick-up in two) with a postoperative 248.4 Hz. Using the Mann-Whitney <em>U</em> test, we found a statistically significant improvement in MPT, VHI, and GRBAS of the patients. There was no significant improvement in the FO of the patients. There was no postoperative voice deterioration in any patient. A preoperative phonatory gap was found in all patients, which postoperatively was absent in 10, markedly decreased in three, present in one with stroboscopy revealing an improvement in mucosal wave amplitude in 13 patients. In four patients with deep bilateral sulci where the LASR had been ligament deep, VHI improved from 26 to 13.3, GRBAS from 12 to 6.5, and MPT from 4.3 to 9.5 seconds. Using the Mann-Whitney <em>U</em> test, all three parameters were significantly improved.</div></div><div><h3>Conclusion</h3><div>A statistically significant vocal improvement in VHI, GRBAS, and MPT was observed at 3 months, in superficial and deep sulci, operated by LASR. LASR is a simple, quick, and easily replicable surgery. Larger multi-centric studies with long-term follow-up are recommended.</div></div>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":"40 1","pages":"Pages 52-59"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10430651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
To analyze the association between communicative competence self-assessment and interpersonal communication self-perception and voice symptoms in university professors.
Method
Cross-sectional, analytical, observational study in 322 professors, who answered sociodemographic and occupational questions and three self-perception protocols: Self-Assessment of Communication Competence (SACCom), Interpersonal Communication Competence Scale (ICCS), and Voice Symptom Scale (VoiSS). The dependent variable was SACCom’s yes/no answers. Univariate and multivariate descriptive and inferential data analyses were performed through logistic regression.
Results
Most professors were females (55.3%), worked 40 hours (96.6%), and self-reported voice symptoms (72.7%). The largest portion had been in the career for 11–22 years (38.2%). The final multivariate model demonstrated that better self-assessed communicative competence among professors (SACCom) is related to an absence of voice complaints (odds ratio (OR) = 2.17; 95% confidence interval (CI) 1.29–3.65) and better self-perceived interpersonal communication (ICCS) (OR = 1.05; 95% CI 1.02–1.08). The older the professor (OR = 1.03; 95% CI 1.01–1.06), the better their communicative competence (SACCom).
Conclusions
Study professors’ self-assessed communicative competence is predominantly high. Those with a better communicative competence self-assessment are older and vocally healthy and self-perceive greater interpersonal communication skills.
{"title":"University Professors’ Communicative Competence and Its Relationship With Interpersonal Communication and Voice Symptoms","authors":"Caroline Azevedo Maciel , Adriane Mesquita de Medeiros , Letícia Caldas Teixeira","doi":"10.1016/j.jvoice.2023.08.025","DOIUrl":"10.1016/j.jvoice.2023.08.025","url":null,"abstract":"<div><h3>Objective</h3><div>To analyze the association between communicative competence self-assessment and interpersonal communication self-perception and voice symptoms in university professors.</div></div><div><h3>Method</h3><div><span><span>Cross-sectional, analytical, observational study in 322 professors, who answered sociodemographic and occupational questions and three self-perception protocols: Self-Assessment of Communication Competence (SACCom), Interpersonal Communication Competence Scale (ICCS), and Voice Symptom Scale (VoiSS). The </span>dependent variable was SACCom’s yes/no answers. Univariate and multivariate descriptive and inferential data analyses were performed through </span>logistic regression.</div></div><div><h3>Results</h3><div><span>Most professors were females (55.3%), worked 40 hours (96.6%), and self-reported voice symptoms (72.7%). The largest portion had been in the career for 11–22 years (38.2%). The final multivariate model demonstrated that better self-assessed communicative competence among professors (SACCom) is related to an </span>absence of voice complaints (odds ratio (OR) = 2.17; 95% confidence interval (CI) 1.29–3.65) and better self-perceived interpersonal communication (ICCS) (OR = 1.05; 95% CI 1.02–1.08). The older the professor (OR = 1.03; 95% CI 1.01–1.06), the better their communicative competence (SACCom).</div></div><div><h3>Conclusions</h3><div>Study professors’ self-assessed communicative competence is predominantly high. Those with a better communicative competence self-assessment are older and vocally healthy and self-perceive greater interpersonal communication skills.</div></div>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":"40 1","pages":"Pages 229-234"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41160389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.jvoice.2023.08.020
Laura Lamprell, Matthew Broadhurst
Objectives
To present three case reports of cryptococcal laryngitis managed with potassium-titanyl-phosphate (KTP) laser, where only one case managed with KTP laser has previously been published to date to our knowledge. Further, to systematically review the medical literature and describe the epidemiology, clinical assessment, treatment, and prognosis of laryngeal cryptococcosis.
Methods
The PubMed, Embase, and OVID MEDLINE databases were searched using the terms “cryptococcal laryngitis” or “cryptococcus” and “larynx or laryngeal.”
Results
Thirty-eight cases were identified. The median age was 65 years with a 1 male:1.2 female ratio. Thirty-six cases (95%) presented with hoarseness. Twenty-one cases (55%) were systemically immunosuppressed and 19 (50%) were taking an inhaled corticosteroid. This paper lists the five clinical features (i. white exudate or lesion; ii. exophytic, verrucous or tumor-like mass; iii. diffuse erythema; iv. mucosal irregularity; v. thickened vocal fold) and four pathologic features or tests (i. Grocott Gomori Methenamine stain; ii. Mucicarmine stain; iii. fungal or yeast organisms; iv. fungal culture) that encompass 97% of cases of cryptococcal laryngitis reported in the medical literature. In 34 cases (89%), antifungal therapy was given. Four cases (11%) had excisional biopsy and 11 (29%) received combined surgery and medical therapy. There was uncomplicated resolution in 24 cases (63%).
Conclusion
Cryptococcal laryngitis is a rare cause of hoarseness that may be mistaken for malignancy or may be a manifestation of disseminated cryptococcal infection or underlying immunosuppression. Clinicians should be aware of the diagnostic features of cryptococcal laryngitis to facilitate diagnosis and treatment to prevent complicated disease and overly aggressive treatment.
{"title":"Cryptococcal Laryngitis: Three Cases Managed With Potassium-Titanyl-Phosphate Laser and Literature Review","authors":"Laura Lamprell, Matthew Broadhurst","doi":"10.1016/j.jvoice.2023.08.020","DOIUrl":"10.1016/j.jvoice.2023.08.020","url":null,"abstract":"<div><h3>Objectives</h3><div>To present three case reports of cryptococcal laryngitis<span><span> managed with potassium-titanyl-phosphate (KTP) laser, where only one case managed with KTP laser has previously been published to date to our knowledge. Further, to systematically review the medical literature and describe the epidemiology, clinical assessment, treatment, and prognosis of laryngeal </span>cryptococcosis.</span></div></div><div><h3>Methods</h3><div>The PubMed, Embase, and OVID MEDLINE databases were searched using the terms “cryptococcal laryngitis” or “cryptococcus” and “larynx or laryngeal.”</div></div><div><h3>Results</h3><div><span>Thirty-eight cases were identified. The median age was 65 years with a 1 male:1.2 female ratio. Thirty-six cases (95%) presented with hoarseness<span>. Twenty-one cases (55%) were systemically immunosuppressed and 19 (50%) were taking an inhaled corticosteroid. This paper lists the five clinical features (i. white exudate or lesion; ii. exophytic, verrucous or tumor-like mass; iii. diffuse erythema; iv. mucosal irregularity; v. thickened vocal fold) and four pathologic features or tests (i. Grocott Gomori </span></span>Methenamine<span><span> stain; ii. Mucicarmine stain<span>; iii. fungal or yeast organisms; iv. fungal culture) that encompass 97% of cases of cryptococcal laryngitis reported in the medical literature. In 34 cases (89%), </span></span>antifungal therapy was given. Four cases (11%) had excisional biopsy and 11 (29%) received combined surgery and medical therapy. There was uncomplicated resolution in 24 cases (63%).</span></div></div><div><h3>Conclusion</h3><div><span>Cryptococcal laryngitis is a rare cause of hoarseness that may be mistaken for </span>malignancy<span> or may be a manifestation of disseminated cryptococcal infection or underlying immunosuppression. Clinicians should be aware of the diagnostic features of cryptococcal laryngitis to facilitate diagnosis and treatment to prevent complicated disease and overly aggressive treatment.</span></div></div>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":"40 1","pages":"Pages 257.e15-257.e32"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41217951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.jvoice.2023.07.031
Dylan J. Cooper, Seth E. Kaplan
Objectives
Inflammatory reaction to vocal fold injection laryngoplasty with hyaluronic acid (HA) is a rare condition whose optimal management is not established. In this study, we aim to review the presentation of these reactions and outline an approach for evaluation and management.
Methods
We performed a retrospective review of all patients at our institution who underwent vocal fold injection augmentation with HA during the period extending from August 2018 until October 2022. We then identified patients with postinjection inflammatory reaction and reviewed demographic data, indication for injection, amount of HA injected, setting of procedure, and symptoms. The types of complication, management plan, onset, and time to complete resolution were also recorded. A comprehensive literature search for similar complications was conducted for comparative analysis. Once the available data were aggregated with our institutional experience, we developed an algorithmic approach to manage this condition.
Results
We identified 83 patients (124 vocal folds) who underwent vocal fold injection laryngoplasty with HA over a 4-year period. Four patients (4.8%) had a postprocedure inflammatory reaction (5.6% of all vocal folds). Of the four patients, three presented with dyspnea and stridor, while one presented with dysphonia, with onset of symptoms ranging from 24 to 48 hour postinjection. All patients were treated with corticosteroids. For comparative analysis, we identified 24 patients from the literature with reported inflammatory reactions to HA.
Conclusion
We suggest an algorithmic approach to managing laryngeal inflammation following HA injection. Familiarity with treatment for this rare complication is essential to avoid significant morbidity and achieve optimal outcomes.
{"title":"Evaluation and Management of Inflammatory Reactions to Vocal Fold Injection Laryngoplasty with Hyaluronic Acid","authors":"Dylan J. Cooper, Seth E. Kaplan","doi":"10.1016/j.jvoice.2023.07.031","DOIUrl":"10.1016/j.jvoice.2023.07.031","url":null,"abstract":"<div><h3>Objectives</h3><div><span>Inflammatory reaction to vocal fold injection </span>laryngoplasty<span> with hyaluronic acid (HA) is a rare condition whose optimal management is not established. In this study, we aim to review the presentation of these reactions and outline an approach for evaluation and management.</span></div></div><div><h3>Methods</h3><div>We performed a retrospective review of all patients at our institution who underwent vocal fold injection augmentation with HA during the period extending from August 2018 until October 2022. We then identified patients with postinjection inflammatory reaction and reviewed demographic data, indication for injection, amount of HA injected, setting of procedure, and symptoms. The types of complication, management plan, onset, and time to complete resolution were also recorded. A comprehensive literature search for similar complications was conducted for comparative analysis. Once the available data were aggregated with our institutional experience, we developed an algorithmic approach to manage this condition.</div></div><div><h3>Results</h3><div><span>We identified 83 patients (124 vocal folds) who underwent vocal fold injection laryngoplasty with HA over a 4-year period. Four patients (4.8%) had a postprocedure inflammatory reaction (5.6% of all vocal folds). Of the four patients, three presented with dyspnea and stridor, while one presented with </span>dysphonia, with onset of symptoms ranging from 24 to 48 hour postinjection. All patients were treated with corticosteroids. For comparative analysis, we identified 24 patients from the literature with reported inflammatory reactions to HA.</div></div><div><h3>Conclusion</h3><div>We suggest an algorithmic approach to managing laryngeal inflammation following HA injection. Familiarity with treatment for this rare complication is essential to avoid significant morbidity and achieve optimal outcomes.</div></div><div><h3>Level of Evidence</h3><div>4</div></div>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":"40 1","pages":"Pages 60-66"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10500247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01Epub Date: 2025-12-08DOI: 10.1016/j.jvoice.2025.11.006
Michael S Benninger
{"title":"Harvey M. Tucker, November 27, 1938-August 17, 2025.","authors":"Michael S Benninger","doi":"10.1016/j.jvoice.2025.11.006","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.11.006","url":null,"abstract":"","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":"40 1","pages":"1-2"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145967550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.jvoice.2023.08.005
Keith A. Chadwick , David Liao , Isaac L. Alter , Rachel Coleman , Katerina Andreadis , Rebecca Riekki , Jack Waldman , Hal Rives , Mary Pitti , Anaïs Rameau
Objectives
There is currently no research reporting solely on outcomes of voice and communication modification training (VCMT) in individuals who identify as non-binary and genderqueer (NBGQ) in the English literature. This study aimed to describe the objective and subjective impact of VCMT on the voice of NBGQ individuals undergoing a 12-week gender-affirming VCMT program.
Methods
A retrospective consecutive case series of NBGQ individuals enrolled in a VCMT program was performed. Demographics, Transgender Self-Evaluation Questionnaire (TSEQ), fundamental frequency (F0), and frequency range were collected before and after the program.
Results
Four NBGQ individuals enrolled between January 2019 and June 2021; the mean age was 27.0 years. While all four participants represented in this case series showed improvement in at least one of their initial goals, only one improved both their F0 and TSEQ scores; the other three participants had mixed results.
Conclusion
NBGQ individuals experienced improvements in self-reported outcomes and changes in acoustic measures after completing VCMT in our case series. Individuals experienced significant improvement in subjective outcomes despite small changes in acoustic measures, and vice versa. More research is needed to better understand the voice and communication needs of NBGQ individuals, along with their outcomes with VCMT.
{"title":"Outcomes of Gender-Affirming Voice and Communication Modification Training for Non-binary Individuals: A Case Series","authors":"Keith A. Chadwick , David Liao , Isaac L. Alter , Rachel Coleman , Katerina Andreadis , Rebecca Riekki , Jack Waldman , Hal Rives , Mary Pitti , Anaïs Rameau","doi":"10.1016/j.jvoice.2023.08.005","DOIUrl":"10.1016/j.jvoice.2023.08.005","url":null,"abstract":"<div><h3>Objectives</h3><div>There is currently no research reporting solely on outcomes of voice and communication modification training (VCMT) in individuals who identify as non-binary and genderqueer (NBGQ) in the English literature. This study aimed to describe the objective and subjective impact of VCMT on the voice of NBGQ individuals undergoing a 12-week gender-affirming VCMT program.</div></div><div><h3>Methods</h3><div><span>A retrospective consecutive case series of NBGQ individuals enrolled in a VCMT program was performed. Demographics, Transgender Self-Evaluation Questionnaire (TSEQ), fundamental frequency (F</span><sub>0</sub>), and frequency range were collected before and after the program.</div></div><div><h3>Results</h3><div>Four NBGQ individuals enrolled between January 2019 and June 2021; the mean age was 27.0 years. While all four participants represented in this case series showed improvement in at least one of their initial goals, only one improved both their F<sub>0</sub> and TSEQ scores; the other three participants had mixed results.</div></div><div><h3>Conclusion</h3><div>NBGQ individuals experienced improvements in self-reported outcomes and changes in acoustic measures after completing VCMT in our case series. Individuals experienced significant improvement in subjective outcomes despite small changes in acoustic measures, and vice versa. More research is needed to better understand the voice and communication needs of NBGQ individuals, along with their outcomes with VCMT.</div></div><div><h3>Level of evidence</h3><div>Level 4.</div></div>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":"40 1","pages":"Pages 199-205"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10161255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.jvoice.2023.09.010
Bailey Balouch , Razmig Garabet , Philip J. Maxwell , Harleen K. Sethi , Eli Bress , Omar Ramadan , Robert T. Sataloff
<div><div>The 445-nm blue laser combines the features of photocoagulative vascular lasers and cutting lasers in one device. The purpose of the present study was to evaluate the safety and efficacy of the 445-nm blue laser for the treatment of benign laryngeal pathologies, other than vascular lesions. Outcomes were compared to those when already-established therapies were used.</div></div><div><h3>Methods</h3><div><span>Adult voice center patients who underwent surgical intervention for vocal fold<span> (VF) mass, VF scar, laryngeal stenosis, laryngeal web, or Reinke’s edema were included in this retrospective study. Outcomes were compared to those achieved when traditional treatment modalities were used, including cold steel, CO</span></span><sub>2</sub> laser, potassium-titanyl-phosphate (KTP) laser, and coblator. Strobovideolaryngoscopy footage was evaluated using a previously described model at four time points: postoperative visit #1: 1–14 days, postoperative visit #2: 30–60 days, postoperative visit #3: 61–365 days, postoperative visit #4: >365 days.</div></div><div><h3>Results</h3><div>Eighty cases using the blue laser and 153 controls (n = 78 cold steel, n = 51 KTP laser, n = 22 CO<sub>2</sub><span> laser, n = 2 coblator) were included in this study. Procedures performed using blue laser included VF mass excision (n = 45), VF scar reduction (n = 16), laryngeal stenosis resection/repair (n = 25), laryngeal web excision (n = 7), and reduction of Reinke’s edema (n = 1). On postoperative strobovideolaryngoscopy examination, the surgical objective score did not differ significantly between the blue laser cohort and all controls at any postoperative visit. VF edema did not differ significantly between the blue laser cohort and all controls at any postoperative visit. VF hemorrhage scores were significantly lower in the blue laser cohort compared to all controls at the first postoperative visit, but hemorrhage had resolved almost entirely by the second postoperative visit in all groups. Postoperative VF stiffness was worse in the blue laser group at the third postoperative visit compared to controls, but both groups had improved to similar levels by the fourth postoperative visit. The rate of lesion recurrence (24.29% versus 17.19%) did not differ significantly between the blue laser cohort and controls on multivariate analysis (Odds ratio [OR] = 1.081 [0.461–2.536]). The complication rate (12.50% versus 10.46%) did not differ significantly between the blue laser cohort and all controls on multivariate analysis (OR = 0.992 [0.375–2.624]). The blue laser was associated with a lower rate of revision surgery (30.00% versus 34.64%) on multivariate analysis (OR = 0.380 [0.168–0.859]).</span></div></div><div><h3>Conclusion</h3><div><span>The 445-nm blue laser is safe and effective for the management of benign laryngeal lesions. It has efficacy and safety similar to those of traditional treatment modalities (including cold steel, CO</span><sub>2</sub
{"title":"The Safety and Efficacy of the 445-nm Blue Laser for Operative Management of Benign Nonvascular Laryngeal Lesions","authors":"Bailey Balouch , Razmig Garabet , Philip J. Maxwell , Harleen K. Sethi , Eli Bress , Omar Ramadan , Robert T. Sataloff","doi":"10.1016/j.jvoice.2023.09.010","DOIUrl":"10.1016/j.jvoice.2023.09.010","url":null,"abstract":"<div><div>The 445-nm blue laser combines the features of photocoagulative vascular lasers and cutting lasers in one device. The purpose of the present study was to evaluate the safety and efficacy of the 445-nm blue laser for the treatment of benign laryngeal pathologies, other than vascular lesions. Outcomes were compared to those when already-established therapies were used.</div></div><div><h3>Methods</h3><div><span>Adult voice center patients who underwent surgical intervention for vocal fold<span> (VF) mass, VF scar, laryngeal stenosis, laryngeal web, or Reinke’s edema were included in this retrospective study. Outcomes were compared to those achieved when traditional treatment modalities were used, including cold steel, CO</span></span><sub>2</sub> laser, potassium-titanyl-phosphate (KTP) laser, and coblator. Strobovideolaryngoscopy footage was evaluated using a previously described model at four time points: postoperative visit #1: 1–14 days, postoperative visit #2: 30–60 days, postoperative visit #3: 61–365 days, postoperative visit #4: >365 days.</div></div><div><h3>Results</h3><div>Eighty cases using the blue laser and 153 controls (n = 78 cold steel, n = 51 KTP laser, n = 22 CO<sub>2</sub><span> laser, n = 2 coblator) were included in this study. Procedures performed using blue laser included VF mass excision (n = 45), VF scar reduction (n = 16), laryngeal stenosis resection/repair (n = 25), laryngeal web excision (n = 7), and reduction of Reinke’s edema (n = 1). On postoperative strobovideolaryngoscopy examination, the surgical objective score did not differ significantly between the blue laser cohort and all controls at any postoperative visit. VF edema did not differ significantly between the blue laser cohort and all controls at any postoperative visit. VF hemorrhage scores were significantly lower in the blue laser cohort compared to all controls at the first postoperative visit, but hemorrhage had resolved almost entirely by the second postoperative visit in all groups. Postoperative VF stiffness was worse in the blue laser group at the third postoperative visit compared to controls, but both groups had improved to similar levels by the fourth postoperative visit. The rate of lesion recurrence (24.29% versus 17.19%) did not differ significantly between the blue laser cohort and controls on multivariate analysis (Odds ratio [OR] = 1.081 [0.461–2.536]). The complication rate (12.50% versus 10.46%) did not differ significantly between the blue laser cohort and all controls on multivariate analysis (OR = 0.992 [0.375–2.624]). The blue laser was associated with a lower rate of revision surgery (30.00% versus 34.64%) on multivariate analysis (OR = 0.380 [0.168–0.859]).</span></div></div><div><h3>Conclusion</h3><div><span>The 445-nm blue laser is safe and effective for the management of benign laryngeal lesions. It has efficacy and safety similar to those of traditional treatment modalities (including cold steel, CO</span><sub>2</sub","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":"40 1","pages":"Pages 73-81"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41146196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Resonance properties of the nasal and sinus cavities are involved in the individuality of speech. However, detailed information on how alterations in the nasal cavity morphology affect voice quality is lacking. The aim of the present study was to investigate the effects of structural changes in the nasal cavity on voice production by spraying a topical adrenaline solution with a vasoconstrictive effect into the nasal cavity, causing nasal mucosal contraction.
Study Design
Prospective.
Methods
Overall, 51 adult volunteers were recruited from the Otorhinolaryngology Outpatient Department of the Jikei University Hospital from June to September 2022. Among them, 20 completed acoustic rhinometry and voice recordings before and after adrenaline spraying. The nasal consonant [N] uttered with the mouth completely closed was recorded for 5 seconds. The remaining 31 volunteers completed all auditory experiments. This was conducted to determine whether the changes in voice before and after adrenaline spraying could be discriminated against by the participants.
Results
The nasal volume had increased 5 and 10 minutes after spraying compared to that before spraying, reaching a significance at 10 minutes (P = 0.06). It had increased at 2 and 5 cm from the external nostrils compared to that within 3 cm of the external nostrils (P = 0.04). Among the 31 volunteers in the auditory experiments, 30 had a discrimination rate >90%, with a mean of 96.3% (standard error, 3.2). The spectral envelope of the 16 frequency bands varied significantly at 500-Hz increments (P = 0.0006). In particular, changes in the high-frequency bands were larger between 4500 and 6000 Hz.
Conclusions
Nasal enlargement with 0.02% topical adrenaline affects the spectral envelope, particularly in the high-frequency bands between 4500 and 6000 Hz, and perceptibly alters the voice.
{"title":"Effects of Increased Nasal Volume due to Topical Adrenaline on the Voice","authors":"Ryoji Oguro , Kazuhiro Omura , Norihiko Uchio , Norie Imagawa , Tatsuya Kitamura , Hironori Takemoto , Nobuyoshi Otori","doi":"10.1016/j.jvoice.2023.08.013","DOIUrl":"10.1016/j.jvoice.2023.08.013","url":null,"abstract":"<div><h3>Objectives</h3><div>Resonance properties of the nasal and sinus cavities are involved in the individuality of speech. However, detailed information on how alterations in the nasal cavity<span> morphology affect voice quality is lacking. The aim of the present study was to investigate the effects of structural changes in the nasal cavity on voice production by spraying a topical adrenaline solution with a vasoconstrictive effect into the nasal cavity, causing nasal mucosal contraction.</span></div></div><div><h3>Study Design</h3><div>Prospective.</div></div><div><h3>Methods</h3><div><span><span>Overall, 51 adult volunteers were recruited from the Otorhinolaryngology Outpatient Department of the Jikei University Hospital from June to September 2022. Among them, 20 completed </span>acoustic rhinometry and voice recordings before and after adrenaline spraying. The nasal consonant [N] uttered with the </span>mouth completely closed was recorded for 5 seconds. The remaining 31 volunteers completed all auditory experiments. This was conducted to determine whether the changes in voice before and after adrenaline spraying could be discriminated against by the participants.</div></div><div><h3>Results</h3><div>The nasal volume had increased 5 and 10 minutes after spraying compared to that before spraying, reaching a significance at 10 minutes (<em>P</em> = 0.06). It had increased at 2 and 5 cm from the external nostrils compared to that within 3 cm of the external nostrils (<em>P</em> = 0.04). Among the 31 volunteers in the auditory experiments, 30 had a discrimination rate >90%, with a mean of 96.3% (standard error, 3.2). The spectral envelope of the 16 frequency bands varied significantly at 500-Hz increments (<em>P</em> = 0.0006). In particular, changes in the high-frequency bands were larger between 4500 and 6000 Hz.</div></div><div><h3>Conclusions</h3><div>Nasal enlargement with 0.02% topical adrenaline affects the spectral envelope, particularly in the high-frequency bands between 4500 and 6000 Hz, and perceptibly alters the voice.</div></div>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":"40 1","pages":"Pages 251.e17-251.e21"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10278948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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