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Medical thermography as a method to assessment of burn depth and treatment effectiveness in patients with burn injury 医学热像仪评价烧伤患者烧伤深度及治疗效果的方法
Pub Date : 2023-11-08 DOI: 10.33667/2078-5631-2023-22-56-62
M. G. Volovik, I. M. Dolgov, Y. V. Karamyshev, I. A. Loshenko, V. S. Koskin
In this revue discuss the usefulness of static and active dynamic thermography for burn depth assessment as well as for estimation of the effectiveness of the different treatment modalities (cell therapy, humid ambience, evaluation of the donor skin area).
本文讨论了静态和主动动态热成像对烧伤深度评估的有用性,以及对不同治疗方式(细胞治疗、潮湿环境、供体皮肤面积评估)有效性的评估。
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引用次数: 0
Vulvoscopy: anachronism or a time-tested method? 外阴镜检查:不合时宜还是久经考验的方法?
Pub Date : 2023-11-08 DOI: 10.33667/2078-5631-2023-24-46-50
A. V. Ignatovsky
Objective. Due to the growing number of patients with various diseases of the vulva, there is a need to evaluate the available diagnostic tools. Vulvoscopy is one of the widely used methods, the diagnostic sensitivity and specificity of which varies significantly. Purpose of the work. Based on the analysis of publications to determine the diagnostic significance of vulvoscopy. Material and methods. The data of modern research and publications were used in the preparation of the work. Results. The authors of a number of publications warn against considering vulvoscopy as a variant of colposcopy. A high percentage of false positive results when performing tests with acetic acid may be due to a variety of reasons and is not highly specific for papillomavirus infection. The use of the test with toluidine blue is not recommended due to low sensitivity. Conclusions. A positive aspect of vulvoscopy is the ability to examine the vulva area with optical magnification, in a position convenient for examining the patient, which makes it possible to identify areas to be biopsied. The use of additional tests with acetic acid should be limited, and tests with toluidine blue and Lugol solution are not recommended due to low sensitivity.
目标。由于越来越多的患者患有各种外阴疾病,有必要评估现有的诊断工具。外阴镜检查是广泛应用的方法之一,其诊断敏感性和特异性差异较大。工作目的。通过对文献的分析,确定外阴镜检查的诊断意义。材料和方法。在准备工作中使用了现代研究和出版物的数据。结果。许多出版物的作者警告不要将外阴镜视为阴道镜的一种变体。当用乙酸进行测试时,假阳性结果的高比例可能是由于各种原因造成的,并且对乳头瘤病毒感染没有高度特异性。由于灵敏度低,不建议使用甲苯胺蓝进行测试。结论。外阴镜检查的一个积极方面是能够用光学放大镜检查外阴区域,在方便检查患者的位置,这使得有可能确定要活检的区域。应限制使用醋酸进行附加试验,由于灵敏度低,不建议使用甲苯胺蓝和Lugol溶液进行试验。
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引用次数: 0
Studying the commitment to physical activity of medical university students 医科大学生体育活动投入的研究
Pub Date : 2023-11-08 DOI: 10.33667/2078-5631-2023-26-46-49
S. A. Sapozhnikov
The basis of a healthy lifestyle is not only the rejection of bad habits, but also an increase in physical activity (FA). The importance of FA for medical university students is due to the fact that their future profession involves promoting a healthy lifestyle, including FA, among the population. The purpose of the study included studying the FA of medical university students in different courses of study. An online survey of 306 medical university students was conducted using a Scale of Exercise Benefits/barriers. It was found that a greater number of benefits from physical education and a smaller number of barriers were revealed in 1st-year students and a progressive change in this ratio in older students. The analysis of the FA of medical students revealed that 1st year students devote more time to physical activity (sports) in comparison with undergraduates. The main reason for the low FA among students is the lack of free time. During the COVID-19 pandemic, with the transition to online education, students noted a decrease in FA and dissatisfaction with physical education in remote mode. Based on the data obtained, it was concluded that in order for medical students to adequately provide counseling to their patients in the future, medical universities should develop programs that stimulate medical students to greater FA.
健康生活方式的基础不仅是拒绝坏习惯,而且还包括增加体育活动。FA对医科大学学生的重要性是由于他们未来的职业涉及在人群中推广健康的生活方式,包括FA。本研究的目的是研究医科大学学生在不同课程中的FA。一项针对306名医科大学学生的在线调查使用了“运动益处/障碍”量表。研究发现,一年级学生从体育教育中获益较多,障碍较少,而在高年级学生中这一比例逐渐变化。医学生的FA分析显示,大一学生比本科生投入更多的时间进行体育活动(运动)。学生的FA低的主要原因是缺乏空闲时间。在新冠肺炎大流行期间,随着在线教育的过渡,学生们注意到远程模式体育的FA和不满程度有所下降。基于所获得的数据,我们得出结论,为了医学生将来能够充分地为他们的病人提供咨询,医科大学应该制定刺激医学生更大的FA的计划。
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引用次数: 0
Efficacy and safety of isotretinoin Lidose® 异维a酸Lidose®的有效性和安全性
Pub Date : 2023-11-08 DOI: 10.33667/2078-5631-2023-24-36-40
L. S. Kruglova, N. V. Gryazeva, A. V. Tamrazova
Introduction. Acne is a common chronic inflammatory disease, which is accompanied by severe social stress and reduces the quality of life of patients. Isotretinoin is the gold standard for the treatment of severe and moderate forms of acne, and is also used when there is a risk of developing a post-acne symptom complex and when previous treatment methods are ineffective. Purpose of the study. To determine the effectiveness and safety of various isotretinoin regimens at a dose of 0.4–0.8 mg/kg in patients with moderate to severe acne vulgaris and in patients with adult acne. Materials and methods. A single-center, prospective, parallel, controlled study involved 139 patients with acne vulgaris and adult acne, who were divided into 3 groups. 72 patients with acne vulgaris of moderate severity according to the IGA scale (group A1) and 37 patients with adult acne (group B) received isotretinoin (Accutane) at a dose of 0.4 mg/kg/day (cumulative dose 100 mg/kg) for 8 months. 30 patients with severe forms of acne vulgaris (group A1) received Accutane at a dose of 0.8 mg/kg/day (cumulative dose 120 mg/kg) for 8 months. The study lasted 24 months. and consisted of 4 visits (1st visit, 4, 8 and 24 months), at each visit photocontrol was performed, the number of inflammatory and non-inflammatory elements was calculated, the DAI index and the degree on the IGA scale were determined. Results. All 139 patients achieved ‘clear’ or almost ‘clear’ skin according to the IGA scale after 8 months of therapy. There was also a statistically significant decrease in non-inflammatory and inflammatory elements in all groups after 4 and 8 months. (p < 0.001). The total DIA score after 8 months was reduced in group A1 by 89.2%, in group A2 by 83.78% and in group B by 80.3%. Acne recurrence after 24 months was determined in five patients. Conclusions. Various regimens of Accutane for moderate and severe acne vulgaris, as well as adult acne, have demonstrated high efficacy and a favorable safety profile.
介绍。痤疮是一种常见的慢性炎症性疾病,伴随着严重的社会压力,降低了患者的生活质量。异维甲酸是治疗严重和中度痤疮的黄金标准,也用于有痤疮后症状复杂的风险和以前的治疗方法无效的情况。研究目的:探讨不同异维甲酸方案在0.4 ~ 0.8 mg/kg剂量下对中重度寻常痤疮患者和成人痤疮患者的有效性和安全性。材料和方法。本研究采用单中心、前瞻性、平行对照研究方法,将139例普通痤疮和成人痤疮患者分为3组。根据IGA量表,72例中度寻常性痤疮患者(A1组)和37例成人痤疮患者(B组)接受异维甲酸(Accutane)治疗,剂量为0.4 mg/kg/天(累积剂量为100 mg/kg),疗程8个月。30例重度寻常型痤疮患者(A1组)接受阿库坦治疗,剂量为0.8 mg/kg/天(累积剂量为120 mg/kg),疗程8个月。这项研究持续了24个月。共4次就诊(第1次就诊、第4次就诊、第8次就诊和第24个月就诊),每次就诊时进行光控,计算炎症和非炎症因子的数量,测定DAI指数和IGA量表上的程度。结果。治疗8个月后,所有139例患者的IGA评分均达到“透明”或“几乎透明”。4个月和8个月后,各组非炎症因子和炎症因子均有统计学意义的下降。(p & lt;0.001)。8个月后,A1组DIA总分下降89.2%,A2组下降83.78%,B组下降80.3%。5例患者24个月后痤疮复发。结论。对于中度和重度寻常性痤疮,以及成人痤疮的各种方案,已经证明了高疗效和良好的安全性。
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引用次数: 0
Evaluation of effectiveness of complex therapy for limited eczematous (spongiotic) dermatosis in children and adolescents using local low-frequency magnetotherapy 局部低频磁疗治疗儿童和青少年局限性湿疹(海绵状)皮肤病的疗效评价
Pub Date : 2023-11-08 DOI: 10.33667/2078-5631-2023-24-62-65
A. S. Iskra, E. L. Iskra, G. A. Suslova, D. V. Zaslavsky
The search for modern and affordable methods for the treatment of dermatoses remains an urgent problem in domestic dermatology. The results of recent studies indicate the high therapeutic efficacy of various types of magnetotherapy. The course application of a local low-frequency magnetic field reduces the inflammatory response and helps to restore the structure of the epidermis and dermis in the affected areas of the skin. Purpose of the study. To study the safety and efficacy of local magnetic therapy in a limited form of spongiotic dermatosis with a violation of the skin barrier in children and adolescents. Material and methods. The study involved 44 children aged 5 to 16 years. The patients were divided into two groups: the first group combined external therapy and local low-frequency magnetotherapy, the patients of the second group received external therapy and placebo in physiotherapy treatment. Results. According to the study, the efficacy and safety of local magnetic therapy in focal pruritic dermatosis in combination with basic external agents and a faster treatment result with prolonged remission are confirmed. Conclusions. The use of local magnetic therapy in combination with standard external therapy contributes to the relief of clinical symptoms of local eczematous dermatosis and improves the quality of life of patients.
寻找现代和负担得起的方法治疗皮肤病仍然是一个紧迫的问题,在国内皮肤科。近年来的研究结果表明,各种类型的磁疗都有很高的治疗效果。局部低频磁场的应用减少了炎症反应,并有助于恢复皮肤患处表皮和真皮层的结构。研究目的:研究局部磁疗在儿童和青少年侵犯皮肤屏障的有限形式海绵状皮肤病中的安全性和有效性。材料和方法。这项研究涉及44名5至16岁的儿童。将患者分为两组:第一组患者采用外置治疗和局部低频磁疗联合治疗,第二组患者在物理治疗中采用外置治疗和安慰剂治疗。结果。本研究证实局部磁疗联合基础外用药物治疗局灶性瘙痒性皮肤病的有效性和安全性,治疗效果较快,缓解期延长。结论。局部磁疗配合标准外治疗法,有助于缓解局部湿疹性皮肤病的临床症状,提高患者的生活质量。
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引用次数: 0
Long-term effects of chemotherapy in patients with acute leukemia in childhood 化疗对儿童急性白血病患者的长期影响
Pub Date : 2023-11-08 DOI: 10.33667/2078-5631-2023-26-27-30
N. V. Orlova, N. D. Karseladze, O. A. Tiganova, L. I. Ilyenko
An increase in the survival rate of patients who had cancer in childhood determines the need to study the long-term consequences of the treatment. Long-term complications may develop from various organs and systems: active studies of the toxicity of chemotherapy are carried out in the field of pharmacogenetics, respiratory, cardiovascular, sensorineural and endocrine systems, as well as skin, central nervous system, immune system and others. The treatment of acute leukemia carried out in childhood can significantly reduce the quality of life, cause cognitive and psychoemotional disorders. Experts in the field of pediatric hematology-oncology proposed to create an indicator called «survival without pronounced toxicity». A group of scientists initiated an international project to study the outcomes of childhood malignant tumors. Among the long-term consequences, it is planned to assess the quality of life and the development of complications. The study of long-term complications of leukemia treatment will allow us to develop algorithms for the prevention and follow-up of these patients.
儿童期癌症患者存活率的提高决定了研究这种治疗的长期后果的必要性。长期并发症可能发生在各个器官和系统:药物遗传学、呼吸系统、心血管系统、感觉神经系统和内分泌系统以及皮肤、中枢神经系统、免疫系统等领域对化疗的毒性进行了积极的研究。急性白血病在儿童期进行治疗会显著降低患者的生活质量,引起认知和心理情绪障碍。儿科血液肿瘤学领域的专家建议创建一个名为“无明显毒性生存”的指标。一组科学家发起了一项研究儿童恶性肿瘤后果的国际项目。在长期后果中,计划评估生活质量和并发症的发展。对白血病治疗的长期并发症的研究将使我们能够开发出预防和随访这些患者的算法。
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引用次数: 0
Deep inspiration electrocardiogram test: physiologic mechanisms and diagnostic capabilities 深吸气心电图试验:生理机制和诊断能力
Pub Date : 2023-11-08 DOI: 10.33667/2078-5631-2023-22-36-42
V. S. Barkan, D. V. Drozdov, G. G. Rezvetsov
The article reflects modern concepts about the effect of deep inspiration and breath holding on the heart functioning and the reflection of these processes at ECGs. Positional changes of Q waves, primarily in leads III and aVF, and their possible differences from pathological Q waves are described. Reflex and humoral effects of deep inspiration and breath holding on heart functions such as contractility, automatism and conductivity are considered. Examples of rhythm and conduction disturbances that rarely occur during breath holding are illutrated on ECGs. A recommended variant of the implementation of the deep inspiration ECG test using computer ECG systems is described, which implements continuous ECG recording on free breathing, during inspiration and while holding the breath. This version of the test does not change the operators’ complexity and time of ECG registration.
这篇文章反映了关于深吸气和屏气对心脏功能的影响的现代概念以及这些过程在心电图上的反映。本文描述了主要在导联III和aVF处的Q波位置变化及其与病理Q波的可能差异。深吸气和屏气对心脏功能的反射和体液作用,如收缩性、自动性和传导性。屏气期间很少发生的节律和传导障碍的例子在心电图上有说明。本文介绍了一种推荐的利用计算机心电系统实现深吸气心电测试的变体,它实现了自由呼吸、吸气和屏气时的连续心电记录。该版本的测试不改变操作人员心电注册的复杂度和时间。
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引用次数: 0
Anticoagulant therapy in patients with atrial fibrillation and chronic kidney disease: Arguments for or against 房颤和慢性肾病患者的抗凝治疗:支持或反对的争论
Pub Date : 2023-11-08 DOI: 10.33667/2078-5631-2023-25-14-20
A. G. Komarova, N. L. Lyakhova, S. D. Covantsev, E. A. Naryshkina, D. V. Slepukhova
Atrial fibrillation and chronic renal failure are common diseases in the population with similar risk factors. Both conditions are independent riskfactors for the development of thromboembolic complications. There is compelling evidence to support the benefits of anticoagulant therapy for atrial fibrillation in the general population, but in patients with advanced chronic renal failure, the use of anticoagulants may be limited. A number of studies have shown conflicting results, and this topic is of interest for further discussion and a comprehensive analysis of the existing data.
心房颤动和慢性肾衰竭是人群中常见的疾病,具有相似的危险因素。这两种情况都是血栓栓塞并发症发生的独立危险因素。有令人信服的证据支持抗凝治疗心房颤动在一般人群中的益处,但在晚期慢性肾功能衰竭患者中,抗凝治疗的使用可能受到限制。许多研究显示出相互矛盾的结果,这一主题值得进一步讨论和对现有数据进行全面分析。
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引用次数: 0
Methodology of electromyography of the lumbar paraspinal muscles 腰椎棘旁肌肌电图的方法学
Pub Date : 2023-11-08 DOI: 10.33667/2078-5631-2023-22-29-34
E. G. Seliverstova, M. V. Sinkin, A. Y. Kordonsky, A. A. Grin
Electromyography (EMG) of the lumbar paraspinal muscles (PM) is performed for differential diagnosis of lumbosacral radiculopathy and other proximal peripheral nerve injuries such as lumbosacral plexopathy or sciatic neuropathy. In neurosurgery, EMG of the lumbar PM can clarify the level of the compressed spinal nerve root in polyradiculopathy due to degenerative spinal deasese. In this article we describe in detail the technique of the study, present the factors limiting the use of EMG in the diagnosis of radiculopathy and determination of its anatomical level.
腰椎旁肌肌电图(EMG)用于腰骶神经根病和其他近端周围神经损伤(如腰骶神经丛病或坐骨神经病变)的鉴别诊断。在神经外科中,腰椎PM的肌电图可以明确退行性脊柱疾病引起的多神经根病的脊神经根受压程度。在这篇文章中,我们详细描述了这项研究的技术,提出了限制肌电图用于神经根病诊断和确定其解剖水平的因素。
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引用次数: 0
Coherent analysis in electroencephalography. Experience in the use of coherent analysis in the assessment of disorders of human mental functions in practical electroencephalography. (Lecture three) 脑电图的连贯分析。在实际脑电图中使用连贯分析评估人类心理功能障碍的经验。(三个讲座)
Pub Date : 2023-11-08 DOI: 10.33667/2078-5631-2023-22-20-28
L. B. Ivanov, A. V. Budkevich
It is discussed what actually useful coherent analysis can give in solving the problem of assessing the system- functional organization of cortical rhythms, which underlies the clinical interpretation of quantitative indicators of intracerebral connections. The authors emphasized. That in the basis of the assessment of disorders of the mental function of the brain according to EEG data, one should look for signs of dissociation of the level of wakefulness in non-sleeping people. It is necessary to look for features of the electroencephalographic picture, which can be considered as neurophysiological neurotic patterns and, most importantly, an assessment of the state of the systemic- functional organization of the cortical rhythm, interpreted as a state of hypofrontality. The authors took the path of visual illustration using examples of specific patients with various pathological states of brain function. The features of changes in coherence indices in patients with hyperactivity syndrome, in violation of the function of attention, with mental retardation, in vegetative- vascular dystonia are given. The authors cite the observation of a child with sensorineural hearing loss from birth and connect the fact of a decrease in the level of intertemporal relations, not with the underlying disease, but with the lack of oral speech skills. The paper emphasizes that hypersynchronization of the alpha rhythm is quite pathognomonic to the state of increased anxiety. The authors explain in detail under what states of mental dysfunction the values of the average coherence are more informative, and in which the values of the dominant frequency. In conclusion, the authors complain about the unsatisfactory software capabilities of mathematical processing in some EEG computer systems, so neurophysiologists have unequal opportunities.
讨论了在解决评估皮质节律的系统功能组织的问题时,实际有用的相干分析可以给出什么,这是脑内连接定量指标的临床解释的基础。作者强调。在根据脑电图数据评估大脑精神功能紊乱的基础上,人们应该在不睡觉的人身上寻找清醒水平分离的迹象。有必要寻找脑电图图像的特征,这些特征可以被认为是神经生理学的神经症模式,最重要的是,对皮质节律的系统功能组织状态的评估,解释为下额状态。作者采用视觉说明的方法,以不同脑功能病理状态的特定患者为例。本文介绍了多动综合征、注意力障碍、智力低下、植物性血管张力障碍患者相干性指标的变化特点。作者引用了对一名从出生起就患有感音神经性听力损失的儿童的观察,并将颞间关系水平下降的事实与潜在疾病联系起来,而不是与缺乏口语技能有关。本文强调,阿尔法节律的超同步是焦虑增加状态的典型症状。作者详细解释了在何种精神功能障碍状态下,平均相干性的值更能提供信息,以及在何种状态下主导频率的值更能提供信息。总之,作者抱怨一些脑电图计算机系统的数学处理软件能力不理想,因此神经生理学家的机会不平等。
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引用次数: 0
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Medicinskij alfavit
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