首页 > 最新文献

Journal of Vestibular Research-Equilibrium & Orientation最新文献

英文 中文
Dynamic change of vestibular function and the long-term prognosis of vestibular neuritis. 前庭功能的动态变化和前庭神经炎的长期预后。
IF 2.3 3区 医学 Q2 NEUROSCIENCES Pub Date : 2023-01-01 DOI: 10.3233/VES-220104
Ping Guo, Jieli Zhao, Gaogan Jia, Huawei Li, Wenyan Li

Aim: To comprehensively evaluate the dynamic change of vestibular function during long-term follow-up of vestibular neuritis, as well as the co-relationship with the outcomes of vestibular neuritis (VN), which provides the recommendations for vestibular function tests during the course of VN.

Methods: A prospective cohort study was conducted on 16 patients with acute VN. Caloric test, vHIT, rotatory chair tests, VEMP, dizziness handicap inventory (DHI) score, and dynamic dizzy scales (VAS-DD) was first performed within 7 days of neuritis onset, which were further re-evaluated during the 6-12 months of follow-up. The dynamic changes on multiple objective vestibular examinations were analyzed during the acute and recovery stage of VN. We further evaluated the co-relationship between the vestibular dysfunction scales and the prognosis of VN.

Results: In more than 6 months of follow-up, 44% of the ultralow frequency, 94% of the low-to-mid frequency, and 44% of the high-frequency function of the horizontal semicircular canal returned to normal (p < 0.05). The change degree in symmetry of the rotatory chair test was correlated with the gain of the horizontal semicircular canal on the vHIT and the unilateral weakness (UW) value on the caloric test (p < 0.05). The change in DHI score was correlated with the phase; change in VAS-DD level correlated with the symmetry and TC of the rotatory chair test at VN recovery stage (p < 0.05). There was no significant correlation between the change in DHI score or change in VAS-DD and the degree of vestibular function recovery (p > 0.05).

Conclusion: In general, vestibular function improved during the course of VN. The rotatory chair test can be used to evaluate the overall function of the vestibular system and the compensatory state in patients with VN.

目的:全面评估前庭神经炎长期随访期间前庭功能的动态变化,以及与前庭神经炎(VN)预后的相关性,为VN病程中的前庭功能检测提供建议:方法:对 16 名急性前庭神经炎患者进行了前瞻性队列研究。在神经炎发病 7 天内首次进行了热量测试、vHIT、旋转椅测试、VEMP、头晕障碍量表(DHI)评分和动态头晕量表(VAS-DD),并在 6-12 个月的随访期间进行了进一步评估。我们分析了多种客观前庭检查在 VN 急性期和恢复期的动态变化。我们进一步评估了前庭功能障碍量表与 VN 预后之间的相互关系:在超过 6 个月的随访中,44% 的水平半规管超低频、94% 的中低频和 44% 的高频功能恢复正常(P < 0.05)。旋转椅测试的对称性变化程度与 vHIT 水平半规管增益和热量测试的单侧无力(UW)值相关(P < 0.05)。DHI 评分的变化与阶段相关;VAS-DD 水平的变化与 VN 恢复阶段旋转椅测试的对称性和 TC 相关(P < 0.05)。DHI评分或VAS-DD的变化与前庭功能恢复程度无明显相关性(P>0.05):总的来说,前庭功能在 VN 的治疗过程中得到了改善。旋转椅试验可用于评估前庭系统的整体功能和 VN 患者的代偿状态。
{"title":"Dynamic change of vestibular function and the long-term prognosis of vestibular neuritis.","authors":"Ping Guo, Jieli Zhao, Gaogan Jia, Huawei Li, Wenyan Li","doi":"10.3233/VES-220104","DOIUrl":"10.3233/VES-220104","url":null,"abstract":"<p><strong>Aim: </strong>To comprehensively evaluate the dynamic change of vestibular function during long-term follow-up of vestibular neuritis, as well as the co-relationship with the outcomes of vestibular neuritis (VN), which provides the recommendations for vestibular function tests during the course of VN.</p><p><strong>Methods: </strong>A prospective cohort study was conducted on 16 patients with acute VN. Caloric test, vHIT, rotatory chair tests, VEMP, dizziness handicap inventory (DHI) score, and dynamic dizzy scales (VAS-DD) was first performed within 7 days of neuritis onset, which were further re-evaluated during the 6-12 months of follow-up. The dynamic changes on multiple objective vestibular examinations were analyzed during the acute and recovery stage of VN. We further evaluated the co-relationship between the vestibular dysfunction scales and the prognosis of VN.</p><p><strong>Results: </strong>In more than 6 months of follow-up, 44% of the ultralow frequency, 94% of the low-to-mid frequency, and 44% of the high-frequency function of the horizontal semicircular canal returned to normal (p < 0.05). The change degree in symmetry of the rotatory chair test was correlated with the gain of the horizontal semicircular canal on the vHIT and the unilateral weakness (UW) value on the caloric test (p < 0.05). The change in DHI score was correlated with the phase; change in VAS-DD level correlated with the symmetry and TC of the rotatory chair test at VN recovery stage (p < 0.05). There was no significant correlation between the change in DHI score or change in VAS-DD and the degree of vestibular function recovery (p > 0.05).</p><p><strong>Conclusion: </strong>In general, vestibular function improved during the course of VN. The rotatory chair test can be used to evaluate the overall function of the vestibular system and the compensatory state in patients with VN.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"411-422"},"PeriodicalIF":2.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139075737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Magnetic resonance imaging of endolymphatic hydrops: Controversies and common ground, comment on: "A plea for systematic literature analysis and conclusive study design". 内淋巴积液的磁共振成像:争议与共识,评论:“对系统文献分析和结论性研究设计的请求”。
IF 2.3 3区 医学 Q2 NEUROSCIENCES Pub Date : 2023-01-01 DOI: 10.3233/VES-180663
Jose A Lopez-Escamez, Arnaud Attyé
{"title":"Magnetic resonance imaging of endolymphatic hydrops: Controversies and common ground, comment on: \"A plea for systematic literature analysis and conclusive study design\".","authors":"Jose A Lopez-Escamez,&nbsp;Arnaud Attyé","doi":"10.3233/VES-180663","DOIUrl":"https://doi.org/10.3233/VES-180663","url":null,"abstract":"","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":"33 2","pages":"159-162"},"PeriodicalIF":2.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/VES-180663","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9235040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Vestibular symptoms are related to the proportion of REM sleep in people with sleep complaints: A preliminary report. 前庭症状与睡眠抱怨者快速眼动睡眠的比例有关:一项初步报告。
IF 2.3 3区 医学 Q2 NEUROSCIENCES Pub Date : 2023-01-01 DOI: 10.3233/VES-220113
Ellemarije Altena, Estelle Buguet, Caitlin Higginson, Elliott Lee, Alan Douglass, Naomi Spitale, Rebecca Robillard

Objective/background: Though sleep problems (apnea, insomnia) and related daytime symptoms (fatigue, anxiety, depression) have been associated with vestibular problems (falls, dizziness), it is not well known which particular sleep features relate to vestibular problems. We thus assessed symptoms of vestibular problems in patients visiting a sleep clinic and evaluated how they were associated with objective sleep parameters derived from polysomnography and relevant daytime symptoms.

Patients/methods: The polysomnography data of thirty-one patients (61% female, between 20 and 79 years of age) who were referred for clinical sleep assessment was collated with subjective measures of symptoms linked to vestibular problems (rated on the Situational Characteristics Questionnaire), as well as fatigue, anxiety and depression symptoms. Multiple linear regression was used to identify factors associated with vestibular symptoms, including analyses adjusted for age, sex, medication use and total sleep time.

Results: A higher percentage of REM sleep and more severe anxiety symptoms were independently associated with more severe vestibular symptoms, which survived adjusted analyses. Other sleep stages, as well as as sleep efficiency, apnea-hypopnea index and oxygen saturation were not significantly related to vestibular symptoms.

Conclusions: These results point at vestibular symptoms as possible important and overlooked correlates of variations in sleep architecture in individuals with sleep complaints. Though replication is needed to confirm findings from this limited sample, the results highlight the importance of assessing vestibular symptoms in people with sleep complaints. In particular, further investigations will need to address the potential implication of REM sleep for vestibular functions and the directionality of this relation.

目的/背景:虽然睡眠问题(呼吸暂停、失眠)和相关的白天症状(疲劳、焦虑、抑郁)与前庭问题(跌倒、头晕)有关,但尚不清楚哪些特定的睡眠特征与前庭问题有关。因此,我们评估了到睡眠诊所就诊的患者前庭问题的症状,并评估了这些症状与多导睡眠图得出的客观睡眠参数和相关白天症状之间的关系。患者/方法:对31例接受临床睡眠评估的患者(61%为女性,年龄在20至79岁之间)的多导睡眠图数据与前庭问题相关症状的主观测量(根据情境特征问卷评分)以及疲劳、焦虑和抑郁症状进行整理。多元线性回归用于确定与前庭症状相关的因素,包括调整年龄、性别、药物使用和总睡眠时间的分析。结果:较高的快速眼动睡眠比例和更严重的焦虑症状与更严重的前庭症状独立相关,并在调整分析中幸存下来。其他睡眠阶段、睡眠效率、呼吸暂停低通气指数、血氧饱和度与前庭症状无显著相关性。结论:这些结果指出前庭症状可能是睡眠抱怨个体睡眠结构变化的重要而被忽视的相关因素。虽然需要复制来证实这个有限样本的发现,但结果强调了评估睡眠抱怨者前庭症状的重要性。特别是,进一步的研究将需要解决快速眼动睡眠对前庭功能的潜在影响以及这种关系的方向性。
{"title":"Vestibular symptoms are related to the proportion of REM sleep in people with sleep complaints: A preliminary report.","authors":"Ellemarije Altena, Estelle Buguet, Caitlin Higginson, Elliott Lee, Alan Douglass, Naomi Spitale, Rebecca Robillard","doi":"10.3233/VES-220113","DOIUrl":"10.3233/VES-220113","url":null,"abstract":"<p><strong>Objective/background: </strong>Though sleep problems (apnea, insomnia) and related daytime symptoms (fatigue, anxiety, depression) have been associated with vestibular problems (falls, dizziness), it is not well known which particular sleep features relate to vestibular problems. We thus assessed symptoms of vestibular problems in patients visiting a sleep clinic and evaluated how they were associated with objective sleep parameters derived from polysomnography and relevant daytime symptoms.</p><p><strong>Patients/methods: </strong>The polysomnography data of thirty-one patients (61% female, between 20 and 79 years of age) who were referred for clinical sleep assessment was collated with subjective measures of symptoms linked to vestibular problems (rated on the Situational Characteristics Questionnaire), as well as fatigue, anxiety and depression symptoms. Multiple linear regression was used to identify factors associated with vestibular symptoms, including analyses adjusted for age, sex, medication use and total sleep time.</p><p><strong>Results: </strong>A higher percentage of REM sleep and more severe anxiety symptoms were independently associated with more severe vestibular symptoms, which survived adjusted analyses. Other sleep stages, as well as as sleep efficiency, apnea-hypopnea index and oxygen saturation were not significantly related to vestibular symptoms.</p><p><strong>Conclusions: </strong>These results point at vestibular symptoms as possible important and overlooked correlates of variations in sleep architecture in individuals with sleep complaints. Though replication is needed to confirm findings from this limited sample, the results highlight the importance of assessing vestibular symptoms in people with sleep complaints. In particular, further investigations will need to address the potential implication of REM sleep for vestibular functions and the directionality of this relation.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":"33 3","pages":"165-172"},"PeriodicalIF":2.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6f/f6/ves-33-ves220113.PMC10357186.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9849029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cognitive functions in episodic vestibular disorders: Meniere's disease and vestibular migraine. 偶发性前庭疾病的认知功能:梅尼埃病和前庭偏头痛。
IF 2.3 3区 医学 Q2 NEUROSCIENCES Pub Date : 2023-01-01 DOI: 10.3233/VES-220025
Mehmet Alp Demirhan, Nese Celebisoy

Background: Cognitive deficits have been defined in patients with bilateral and unilateral vestibular loss.

Objective: To investigate cognitive functions in patients with episodic vestibular disorders.

Methods: Nineteen patients with Meniere's disease (MD), 19 patients with vestibular migraine (VM) and 21 age and education matched healthy controls were studied. Mini Mental State Examination assessing global mental status, Reading Span Test and the Stroop Test evaluating working memory, cognitive processing, reading comprehension and attention, Trail Making Test and Benton's Judgment of Line Orientation Test investigating visual processing, visuospatial skills, processing speed were used. Beck depression and anxiety inventories were given to evaluate the emotional status.

Results: Cognitive test results of the MD and VM patients were not significantly different from the healthy controls (p > 0.05) as well as Beck depression scores (p = 0.14). Beck anxiety scores showed significant difference (p = 0.003). VM patients had significantly higher scores than the healthy controls (p = 0.002) on pairwise comparisons. The scores of the MD patients did not reach statistical significance (p = 0.15).

Conclusion: Episodic vestibular disorders like MD and VM without inter-ictal vestibular deficits do not seem to be associated with cognitive impairment. Patients with VM have significantly higher anxiety scores than the healthy controls and MD patients.

背景:认知缺陷在双侧和单侧前庭功能丧失的患者中被定义。目的:探讨发作性前庭功能障碍患者的认知功能。方法:选取19例梅尼埃病(MD)患者、19例前庭偏头痛(VM)患者和21例年龄、文化程度相匹配的健康对照。小心理状态测验评估整体心理状态,阅读广度测验和Stroop测验评估工作记忆、认知加工、阅读理解和注意,轨迹制作测验和本顿线方向判断测验调查视觉加工、视觉空间技能和加工速度。采用贝克抑郁和焦虑量表评估情绪状态。结果:MD和VM患者的认知测试结果与健康对照组比较差异无统计学意义(p > 0.05), Beck抑郁评分与健康对照组比较差异无统计学意义(p = 0.14)。Beck焦虑评分差异有统计学意义(p = 0.003)。两两比较,VM患者得分明显高于健康对照组(p = 0.002)。MD患者的评分差异无统计学意义(p = 0.15)。结论:像MD和VM这样没有前庭内部缺陷的前庭紊乱似乎与认知障碍无关。VM患者的焦虑得分明显高于健康对照组和MD患者。
{"title":"Cognitive functions in episodic vestibular disorders: Meniere's disease and vestibular migraine.","authors":"Mehmet Alp Demirhan,&nbsp;Nese Celebisoy","doi":"10.3233/VES-220025","DOIUrl":"https://doi.org/10.3233/VES-220025","url":null,"abstract":"<p><strong>Background: </strong>Cognitive deficits have been defined in patients with bilateral and unilateral vestibular loss.</p><p><strong>Objective: </strong>To investigate cognitive functions in patients with episodic vestibular disorders.</p><p><strong>Methods: </strong>Nineteen patients with Meniere's disease (MD), 19 patients with vestibular migraine (VM) and 21 age and education matched healthy controls were studied. Mini Mental State Examination assessing global mental status, Reading Span Test and the Stroop Test evaluating working memory, cognitive processing, reading comprehension and attention, Trail Making Test and Benton's Judgment of Line Orientation Test investigating visual processing, visuospatial skills, processing speed were used. Beck depression and anxiety inventories were given to evaluate the emotional status.</p><p><strong>Results: </strong>Cognitive test results of the MD and VM patients were not significantly different from the healthy controls (p > 0.05) as well as Beck depression scores (p = 0.14). Beck anxiety scores showed significant difference (p = 0.003). VM patients had significantly higher scores than the healthy controls (p = 0.002) on pairwise comparisons. The scores of the MD patients did not reach statistical significance (p = 0.15).</p><p><strong>Conclusion: </strong>Episodic vestibular disorders like MD and VM without inter-ictal vestibular deficits do not seem to be associated with cognitive impairment. Patients with VM have significantly higher anxiety scores than the healthy controls and MD patients.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":"33 1","pages":"63-70"},"PeriodicalIF":2.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10771024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Diagnosis of dizziness in the emergency department: A 1-year prospective single-center study. 急诊科眩晕诊断:一项为期1年的前瞻性单中心研究
IF 2.3 3区 医学 Q2 NEUROSCIENCES Pub Date : 2023-01-01 DOI: 10.3233/VES-220109
Adrâa Nouini, Quentin Mat, Christian Van Nechel, Alionka Bostan, Bernard Dachy, Anissa Ourtani

Background: The management of dizziness and vertigo can be challenging in the emergency department (ED). It is important to rapidly diagnose vertebrobasilar stroke (VBS), as therapeutic options such as thrombolysis and anticoagulation require prompt decisions.

Objective: This study aims to assess the rate of misdiagnosis in patients with dizziness caused by VBS in the ED.

Methods and results: The cohort was comprised of 66 patients with a mean age 56 years; 48% were women and 52% men. Among dizzy patients, 14% had VBS. We used Cohen's kappa test to quantify the agreement between two raters -namely, emergency physicians and neurologists -regarding the causes of dizziness in the ED. The Kappa value was 0.27 regarding the final diagnosis of central vertigo disorders and VBS, thus showing the low agreement. We used the χi2 test to show the association between the presence of two or more cardiovascular risk factors and admission to the stroke unit (p = 0.015).

Conclusion: There is a substantial rate of misdiagnosis in patients with dizziness caused by VBS in the ED. To reduce the number of missing diagnoses of VBS in the future, there is a need to train emergency physicians in neurovestibular examinations, including the HINTS examination for acute vestibular syndrome (AVS) and the Dix-Hallpike (DH) maneuver for episodic vestibular syndrome. Using video head impulse test could help reduce the rate of misdiagnosis of VBS in the ED.

背景:头昏和眩晕的处理在急诊科(ED)具有挑战性。快速诊断椎基底动脉卒中(VBS)非常重要,因为溶栓和抗凝等治疗方案需要及时做出决定。目的:本研究旨在评估ed中VBS引起的头晕的误诊率。方法和结果:该队列由66例患者组成,平均年龄56岁;其中女性占48%,男性占52%。在眩晕患者中,14%有VBS。我们使用Cohen's kappa检验来量化两位评分者(即急诊医生和神经科医生)对急诊科头晕原因的一致性。最终诊断为中枢性眩晕障碍和VBS的kappa值为0.27,因此一致性较低。我们使用χ 2检验来显示两种或两种以上心血管危险因素的存在与卒中住院之间的关联(p = 0.015)。结论:急诊科因VBS引起的眩晕患者误诊率较高。为减少未来VBS的漏诊率,有必要对急诊医师进行神经前庭检查培训,包括急性前庭综合征的提示检查(AVS)和发作性前庭综合征的Dix-Hallpike (DH)手法。应用视频头脉冲试验可降低急诊VBS的误诊率。
{"title":"Diagnosis of dizziness in the emergency department: A 1-year prospective single-center study.","authors":"Adrâa Nouini, Quentin Mat, Christian Van Nechel, Alionka Bostan, Bernard Dachy, Anissa Ourtani","doi":"10.3233/VES-220109","DOIUrl":"10.3233/VES-220109","url":null,"abstract":"<p><strong>Background: </strong>The management of dizziness and vertigo can be challenging in the emergency department (ED). It is important to rapidly diagnose vertebrobasilar stroke (VBS), as therapeutic options such as thrombolysis and anticoagulation require prompt decisions.</p><p><strong>Objective: </strong>This study aims to assess the rate of misdiagnosis in patients with dizziness caused by VBS in the ED.</p><p><strong>Methods and results: </strong>The cohort was comprised of 66 patients with a mean age 56 years; 48% were women and 52% men. Among dizzy patients, 14% had VBS. We used Cohen's kappa test to quantify the agreement between two raters -namely, emergency physicians and neurologists -regarding the causes of dizziness in the ED. The Kappa value was 0.27 regarding the final diagnosis of central vertigo disorders and VBS, thus showing the low agreement. We used the χi2 test to show the association between the presence of two or more cardiovascular risk factors and admission to the stroke unit (p = 0.015).</p><p><strong>Conclusion: </strong>There is a substantial rate of misdiagnosis in patients with dizziness caused by VBS in the ED. To reduce the number of missing diagnoses of VBS in the future, there is a need to train emergency physicians in neurovestibular examinations, including the HINTS examination for acute vestibular syndrome (AVS) and the Dix-Hallpike (DH) maneuver for episodic vestibular syndrome. Using video head impulse test could help reduce the rate of misdiagnosis of VBS in the ED.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":"33 3","pages":"195-202"},"PeriodicalIF":2.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10056098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum to: Bilateral vestibulopathy: Diagnostic criteria Consensus document of the Classification Committee of the Bárány Society. 对:双侧前庭病变:诊断标准Bárány学会分类委员会共识文件的勘误。
IF 2.3 3区 医学 Q2 NEUROSCIENCES Pub Date : 2023-01-01 DOI: 10.3233/VES-229002
Michael Strupp, Ji-Soo Kim, Toshihisa Murofushi, Dominik Straumann, Joanna C Jen, Sally M Rosengren, Charles C Della Santina, Herman Kingma
{"title":"Erratum to: Bilateral vestibulopathy: Diagnostic criteria Consensus document of the Classification Committee of the Bárány Society.","authors":"Michael Strupp,&nbsp;Ji-Soo Kim,&nbsp;Toshihisa Murofushi,&nbsp;Dominik Straumann,&nbsp;Joanna C Jen,&nbsp;Sally M Rosengren,&nbsp;Charles C Della Santina,&nbsp;Herman Kingma","doi":"10.3233/VES-229002","DOIUrl":"https://doi.org/10.3233/VES-229002","url":null,"abstract":"","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":"33 1","pages":"87"},"PeriodicalIF":2.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986683/pdf/ves-33-ves229002.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10853994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 249
Commentary to "Reciprocal influences between cognitive decline and vestibular processing". 对“认知能力下降和前庭加工之间的相互影响”的评论。
IF 2.3 3区 医学 Q2 NEUROSCIENCES Pub Date : 2023-01-01 DOI: 10.3233/VES-200723
Sung-Hee Kim
{"title":"Commentary to \"Reciprocal influences between cognitive decline and vestibular processing\".","authors":"Sung-Hee Kim","doi":"10.3233/VES-200723","DOIUrl":"10.3233/VES-200723","url":null,"abstract":"","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"365"},"PeriodicalIF":2.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/VES-200723","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38316167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Local spatial navigation or "steering" in patients with vestibular loss in a virtual reality environment. 前庭功能丧失患者在虚拟现实环境中的局部空间导航或 "转向"。
IF 2.3 3区 医学 Q2 NEUROSCIENCES Pub Date : 2023-01-01 DOI: 10.3233/VES-230065
Carlos Perez-Heydrich, Macie Pile, Dominic Padova, Ashley Cevallos, Phillip Newman, Timothy P McNamara, Zahra N Sayyid, Yuri Agrawal

Background: Patients with vestibular loss have reduced wayfinding ability, but the association between vestibular loss and impaired steering spatial navigation is unclear.

Objective: To evaluate whether vestibular loss is associated with reduced steering navigation performance in a virtual reality (VR) environment containing obstacles.

Methods: 17 ambulatory adults with vestibular loss were age/sex-matched to healthy controls. Participants traversed a VR hallway with obstacles, and their navigation performance was compared using metrics such as collisions, time, total distance travelled, and speed in single and multivariate analysis.

Results: In univariate analysis there was no significant difference in collisions between vestibular patients and controls (1.84 vs. 2.24, p = 0.974). However, vestibular patients took more time, longer routes, and had lower speeds to complete the task (56.9 vs. 43.9 seconds, p < 0.001; 23.1 vs. 22.0 meters, p = 0.0312; 0.417 vs. 0.544 m/s, p < 0.001). These results were confirmed in multivariate analysis.

Conclusions: This study found that patients with vestibular loss displayed slower gait speeds and traveled longer distances, though did not make more collisions, during a VR steering navigation task. Beyond the known influence of vestibular function on gait speed, vestibular loss may also contribute to less efficient steering navigation through an obstacle-laden environment, through neural mechanisms that remain to be elucidated.

背景:前庭功能缺失患者的寻路能力下降,但前庭功能缺失与转向空间导航能力受损之间的关系尚不清楚:方法:将 17 名患有前庭功能丧失的非卧床成人与健康对照组进行年龄/性别匹配。结果:在单变量和多变量分析中,单变量分析结果显示,前庭功能障碍患者的转向导航性能明显降低:在单变量分析中,前庭神经症患者与对照组在碰撞次数上没有明显差异(1.84 vs. 2.24,p = 0.974)。然而,前庭神经症患者完成任务所需的时间更长、路线更长、速度更低(56.9 秒 vs. 43.9 秒,p < 0.001;23.1 米 vs. 22.0 米,p = 0.0312;0.417 米/秒 vs. 0.544 米/秒,p < 0.001)。这些结果在多变量分析中得到了证实:本研究发现,前庭功能缺失患者在进行虚拟现实转向导航任务时步速较慢,行进距离较长,但碰撞次数并不多。除了已知的前庭功能对步速的影响外,前庭功能缺失还可能通过有待阐明的神经机制,导致在充满障碍物的环境中转向导航的效率降低。
{"title":"Local spatial navigation or \"steering\" in patients with vestibular loss in a virtual reality environment.","authors":"Carlos Perez-Heydrich, Macie Pile, Dominic Padova, Ashley Cevallos, Phillip Newman, Timothy P McNamara, Zahra N Sayyid, Yuri Agrawal","doi":"10.3233/VES-230065","DOIUrl":"10.3233/VES-230065","url":null,"abstract":"<p><strong>Background: </strong>Patients with vestibular loss have reduced wayfinding ability, but the association between vestibular loss and impaired steering spatial navigation is unclear.</p><p><strong>Objective: </strong>To evaluate whether vestibular loss is associated with reduced steering navigation performance in a virtual reality (VR) environment containing obstacles.</p><p><strong>Methods: </strong>17 ambulatory adults with vestibular loss were age/sex-matched to healthy controls. Participants traversed a VR hallway with obstacles, and their navigation performance was compared using metrics such as collisions, time, total distance travelled, and speed in single and multivariate analysis.</p><p><strong>Results: </strong>In univariate analysis there was no significant difference in collisions between vestibular patients and controls (1.84 vs. 2.24, p = 0.974). However, vestibular patients took more time, longer routes, and had lower speeds to complete the task (56.9 vs. 43.9 seconds, p < 0.001; 23.1 vs. 22.0 meters, p = 0.0312; 0.417 vs. 0.544 m/s, p < 0.001). These results were confirmed in multivariate analysis.</p><p><strong>Conclusions: </strong>This study found that patients with vestibular loss displayed slower gait speeds and traveled longer distances, though did not make more collisions, during a VR steering navigation task. Beyond the known influence of vestibular function on gait speed, vestibular loss may also contribute to less efficient steering navigation through an obstacle-laden environment, through neural mechanisms that remain to be elucidated.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"377-383"},"PeriodicalIF":2.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138809713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vestibular-Oriented Research Meeting, June 25 - 29, 2023. 前庭导向研究会议,2023年6月25日-29日。
IF 2.3 3区 医学 Q2 NEUROSCIENCES Pub Date : 2023-01-01 DOI: 10.3233/VES-230300
{"title":"Vestibular-Oriented Research Meeting, June 25 - 29, 2023.","authors":"","doi":"10.3233/VES-230300","DOIUrl":"10.3233/VES-230300","url":null,"abstract":"","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":"33 4","pages":"231-278"},"PeriodicalIF":2.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10039446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effects of acute normobaric hypoxia on vestibular-evoked balance responses in humans. 急性常压缺氧对人类前庭诱发平衡反应的影响。
IF 2.3 3区 医学 Q2 NEUROSCIENCES Pub Date : 2023-01-01 DOI: 10.3233/VES-220075
M I B Debenham, T D A Grantham, J D Smirl, G E Foster, B H Dalton

Background: Hypoxia influences standing balance and vestibular function.

Objective: The purpose here was to investigate the effect of hypoxia on the vestibular control of balance.

Methods: Twenty participants (10 males; 10 females) were tested over two days (normobaric hypoxia and normoxia). Participants stood on a force plate (head rotated leftward) and experienced random, continuous electrical vestibular stimulation (EVS) during trials of eyes open (EO) and closed (EC) at baseline (BL), after 5 (H1), 30 (H2) and 55-min (H3) of hypoxia, and 10-min into normoxic recovery (NR). Vestibular-evoked balance responses were quantified using cumulant density, coherence, and gain functions between EVS and anteroposterior forces.

Results: Oxyhemoglobin saturation, end-tidal oxygen and carbon dioxide decreased for H1-3 compared to BL; however, end-tidal carbon dioxide remained reduced at NR with EC (p≤0.003). EVS-AP force peak-to-peak amplitude was lower at H3 and NR than at BL (p≤0.01). At multiple frequencies, EVS-AP force coherence and gain estimates were lower at H3 and NR than BL for females; however, this was only observed for coherence for males.

Conclusions: Overall, vestibular-evoked balance responses are blunted following normobaric hypoxia >30 min, which persists into NR and may contribute to the reported increases in postural sway.

背景:缺氧影响站立平衡和前庭功能。目的:探讨缺氧对前庭平衡控制的影响。方法:20例受试者(男性10例;10名女性)进行了为期两天的测试(常压缺氧和常压缺氧)。参与者站在一个力板上(头部向左旋转),在基线(BL)的睁眼(EO)和闭眼(EC)试验中,在缺氧5 (H1)、30 (H2)和55分钟(H3)后,以及10分钟进入常氧恢复(NR)后,经历随机、连续的前庭电刺激(EVS)。前庭诱发平衡反应通过ev和前后力之间的累积密度、相干性和增益函数进行量化。结果:H1-3组与BL组相比,血红蛋白饱和度、潮末氧、二氧化碳含量降低;然而,随着EC的增加,潮末二氧化碳仍然减少(p≤0.003)。H3和NR组EVS-AP力峰幅值低于BL组(p≤0.01)。在多个频率下,女性在H3和NR时的ev - ap力相干性和增益估计值低于BL;然而,这只观察到男性的一致性。结论:总的来说,在常压缺氧>30分钟后,前庭诱发的平衡反应变得迟钝,这种反应持续到NR,并可能导致体位摇摆的增加。
{"title":"The effects of acute normobaric hypoxia on vestibular-evoked balance responses in humans.","authors":"M I B Debenham,&nbsp;T D A Grantham,&nbsp;J D Smirl,&nbsp;G E Foster,&nbsp;B H Dalton","doi":"10.3233/VES-220075","DOIUrl":"https://doi.org/10.3233/VES-220075","url":null,"abstract":"<p><strong>Background: </strong>Hypoxia influences standing balance and vestibular function.</p><p><strong>Objective: </strong>The purpose here was to investigate the effect of hypoxia on the vestibular control of balance.</p><p><strong>Methods: </strong>Twenty participants (10 males; 10 females) were tested over two days (normobaric hypoxia and normoxia). Participants stood on a force plate (head rotated leftward) and experienced random, continuous electrical vestibular stimulation (EVS) during trials of eyes open (EO) and closed (EC) at baseline (BL), after 5 (H1), 30 (H2) and 55-min (H3) of hypoxia, and 10-min into normoxic recovery (NR). Vestibular-evoked balance responses were quantified using cumulant density, coherence, and gain functions between EVS and anteroposterior forces.</p><p><strong>Results: </strong>Oxyhemoglobin saturation, end-tidal oxygen and carbon dioxide decreased for H1-3 compared to BL; however, end-tidal carbon dioxide remained reduced at NR with EC (p≤0.003). EVS-AP force peak-to-peak amplitude was lower at H3 and NR than at BL (p≤0.01). At multiple frequencies, EVS-AP force coherence and gain estimates were lower at H3 and NR than BL for females; however, this was only observed for coherence for males.</p><p><strong>Conclusions: </strong>Overall, vestibular-evoked balance responses are blunted following normobaric hypoxia >30 min, which persists into NR and may contribute to the reported increases in postural sway.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":"33 1","pages":"31-49"},"PeriodicalIF":2.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10850634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
期刊
Journal of Vestibular Research-Equilibrium & Orientation
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1