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Urban Care for Unpaid Caregivers: Community Voices in the Care Block Program, in Bogotá, Colombia. 城市无偿照料者:哥伦比亚波哥大 "护理街区计划 "中的社区之声。
IF 4.3 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-24 DOI: 10.1007/s11524-024-00899-z
Paula Guevara-Aladino, Olga L Sarmiento, María Alejandra Rubio, Lina María Gómez-García, Zakaria Nadeem Doueiri, Diego Martínez, Abby C King, Adriana Hurtado-Tarazona, Ann Banchoff, Luis A Guzman, María José Álvarez-Rivadulla, Leonardo Palencia

The Care Block of Bogotá, Colombia, is an urban program that offers services for low-income unpaid caregivers. This study aimed to (i) characterize unpaid caregivers' subjective well-being, mental health symptoms, physical activity levels, and use of public spaces linked to the Care Block; (ii) identify caregivers' perceived built and social environment facilitators and barriers to accessing the Care Block facility; and (iii) document the community-led advocacy process to improve the Care Block program. The quantitative component included a subjective well-being and mental health symptoms survey, and the System for Observing Play and Recreation in Communities (SOPARC) instrument. The qualitative component included the Our Voice citizen science method augmented with portable virtual reality equipment to engage participants in advocacy for changes. Participants (median age of 53 years) dedicated a median of 13.8 h a day to unpaid caregiving, had an average subjective well-being score of 7.0, and 19.1% and 23.8% reported having depression and generalized anxiety symptoms respectively. Caregivers reported that the program fosters their perception of purpose, enjoyment, resilience, and cognitive and emotional awareness. SOPARC evaluation showed that most women engaged in moderate to vigorous physical activity. The caregivers highlighted education, physical activity services, and integration of facilities as facilitators to accessing the Care Block program. Poor quality and lack of sidewalks and roads, limited personal safety, and the risk of pedestrian-vehicle collisions were identified as barriers. Virtual Reality sparked compelling dialogue between participants and stakeholders, allowing stakeholders to reflect on an urban program facilitating unpaid care work.

哥伦比亚波哥大的 "关爱街区 "是一项为低收入无酬照护者提供服务的城市计划。这项研究的目的是:(i) 描述无酬照护者的主观幸福感、心理健康症状、体育活动水平以及与照护街区相关的公共空间的使用情况;(ii) 确定照护者认为的建筑和社会环境对使用照护街区设施的促进作用和障碍;(iii) 记录社区主导的改善照护街区计划的宣传过程。定量研究包括主观幸福感和心理健康症状调查,以及社区游戏和娱乐观察系统(SOPARC)工具。定性部分包括 "我们的声音 "公民科学方法,并使用便携式虚拟现实设备,让参与者参与倡导变革。参与者(年龄中位数为 53 岁)每天无偿照顾他人的时间中位数为 13.8 小时,主观幸福感平均得分为 7.0 分,分别有 19.1% 和 23.8% 的人表示有抑郁症和广泛性焦虑症状。护理人员表示,该计划增强了他们的目标感、愉悦感、复原力以及认知和情感意识。SOPARC 评估显示,大多数妇女都参加了中度到剧烈的体育活动。护理人员强调,教育、体育活动服务和设施整合是参与护理街区计划的有利因素。而人行道和道路质量差、缺乏人行道和道路、人身安全受到限制以及行人与车辆发生碰撞的风险则被认为是障碍。虚拟现实技术引发了参与者和利益相关者之间引人注目的对话,使利益相关者能够对促进无偿护理工作的城市计划进行反思。
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引用次数: 0
SchoolHEAT: Racial and Ethnic Inequity in School Temperature. SchoolHEAT:学校温度中的种族和族裔不平等。
IF 4.3 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-24 DOI: 10.1007/s11524-024-00919-y
Kelly K Jones, Varsha Vijay, Shannon N Zenk

Exposure to high environmental temperature is detrimental to health through multiple pathways. This paper describes disparities in school-based high-temperature exposure at metropolitan schools in the United States. Using school location and sociodemographic data from the National Center for Education Statistics, neighborhood data from the US Census Bureau, and land surface temperature (LST) data from the Aqua Earth-observing satellite mission, we find that for every 10% more Black or Hispanic residents in the neighborhood, schools have LST 0.25 °C and 0.38 °C hotter, respectively. When the Black or Hispanic student population is greater than the neighborhood population, LST is an additional 0.20 °C and 0.40 °C for each 10% increase in students over neighborhood population, respectively. Black and Hispanic students are overrepresented in the hottest schools, making up 58.7% of students in the hottest 20% of schools, compared to only 30.0% of students in the coolest 20% of schools.

暴露在高温环境中会通过多种途径损害健康。本文介绍了美国大都市学校暴露于高温环境的差异。利用国家教育统计中心提供的学校位置和社会人口数据、美国人口普查局提供的社区数据以及 Aqua 地球观测卫星任务提供的地表温度数据,我们发现,社区中的黑人或西班牙裔居民每增加 10%,学校的地表温度就会分别升高 0.25 ℃ 和 0.38 ℃。当黑人或西班牙裔学生人数多于社区人口时,学生人数比社区人口每增加 10%,LST 分别增加 0.20 °C 和 0.40 °C。黑人和西班牙裔学生在最炎热学校的比例过高,在最炎热的 20% 学校中占 58.7%,而在最凉爽的 20% 学校中仅占 30.0%。
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引用次数: 0
A Framework for Measuring Neighborhood Walkability for Older Adults-A Delphi Consensus Study. 衡量老年人邻里步行能力的框架--德尔菲共识研究。
IF 4.3 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-03 DOI: 10.1007/s11524-024-00910-7
Daniela Koller, Malte Bödeker, Ulrike Dapp, Eva Grill, Judith Fuchs, Werner Maier, Ralf Strobl

While mobility in older age is of crucial importance for health and well-being, it is worth noting that currently, there is no German language framework for measuring walkability for older adults that also considers the functional status of a person. Therefore, we combined the results of an expert workshop, a literature review, and a Delphi consensus survey. Through this, we identified and rated indicators relevant for walkability for older adults, additionally focusing on their functional status. The expert workshop and the review led to an extensive list of potential indicators, which we hope will be useful in future research. Those indicators were then adapted and rated in a three-stage Delphi expert survey. A fourth additional Delphi round was conducted to assess the relevance of each indicator for the different frailty levels, namely "robust," "pre-frail," and "frail." Between 20 and 28 experts participated in each round of the Delphi survey. The Delphi process resulted in a list of 72 indicators deemed relevant for walkability in older age groups, grouped into three main categories: "Built environment and transport infrastructure," "Accessibility and meeting places," and "Attractiveness and sense of security." For 35 of those indicators, it was suggested that functional status should be additionally considered. This framework represents a significant step forward in comprehensively covering indicators for subjective and objective walkability in older age, while also incorporating aspects of functioning relevant to older adults. It would be beneficial to test and apply the indicator set in a community setting.

虽然老年人的行动能力对健康和幸福至关重要,但值得注意的是,目前还没有一个同时考虑个人功能状况的德语框架来衡量老年人的步行能力。因此,我们结合了专家研讨会、文献综述和德尔菲共识调查的结果。通过这些工作,我们确定了与老年人步行便利性相关的指标并对其进行了评级,同时还关注了老年人的功能状况。通过专家研讨会和文献综述,我们列出了一份内容广泛的潜在指标清单,希望这些指标对未来的研究有所帮助。随后,我们对这些指标进行了调整,并在三阶段德尔菲专家调查中进行了评分。我们又进行了第四轮德尔菲调查,以评估每个指标对不同虚弱程度(即 "强壮"、"虚弱前期 "和 "虚弱")的相关性。每轮德尔菲调查都有 20 到 28 名专家参与。德尔菲法得出了一份 72 项与老年人群步行能力相关的指标清单,分为三大类:"建筑环境和交通基础设施"、"可达性和聚会场所 "以及 "吸引力和安全感"。对于其中的 35 项指标,建议应额外考虑功能状况。这一框架在全面涵盖老年人主观和客观的步行适宜性指标方面迈出了重要一步,同时还纳入了与老年人相关的功能方面。在社区环境中测试和应用这套指标将是有益的。
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引用次数: 0
Inequalities and Trends in Under-Five Mortality Between Formal and Informal Areas in Ouagadougou, Burkina Faso. 布基纳法索瓦加杜古正规和非正规地区五岁以下儿童死亡率的不平等和趋势。
IF 4.3 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-30 DOI: 10.1007/s11524-024-00878-4
Bruno Yempabou Lankoandé, Yacouba Compaoré, Kassoum Dianou, Souleymane Sanogo, Abdramane Soura, Abdoulaye Maïga, Agbessi Amouzou

The physical expansion of the city of Ouagadougou, the capital and largest city of Burkina Faso, subsided in 2015 after the government banned land speculation that contributed to the growth and entrenchment of informal areas. The government subsequently implemented social policies such as free health care for pregnant women and children under 5 years of age. Against this background, we tested the convergence of under-5 mortality trends between formal and informal areas in the city between 2010 and 2019; data covering that period came from the Ouagadougou Health and Demographic Surveillance System (HDSS). The analyses included the calculation of all-cause and cause-specific mortality rates, the implementation of a Poisson regression model, and competing risk models. Over the study period, children in formal areas had lower mortality than those in informal areas. However, the inequality gap decreased over time due to a faster mortality decline in informal areas. This decline was explained by a rapid decline in deaths from malaria and other causes including sepsis, HIV/AIDS, measles, meningitis, and encephalitis. The pursuit of upgrading informal areas and the implementation of social policies targeting the poorest are likely to accelerate the mortality decline in Ouagadougou overall.

瓦加杜古是布基纳法索的首都和最大的城市,政府禁止了助长非正规地区增长和巩固的土地投机活动,此后,瓦加杜古市的实际扩张于 2015 年有所缓解。政府随后实施了孕妇和 5 岁以下儿童免费医疗等社会政策。在此背景下,我们测试了 2010 年至 2019 年间该市正规和非正规地区 5 岁以下儿童死亡率趋势的趋同性;这一时期的数据来自瓦加杜古卫生与人口监测系统(HDSS)。分析包括计算全因死亡率和特定原因死亡率,采用泊松回归模型和竞争风险模型。在研究期间,正规地区儿童的死亡率低于非正规地区儿童。然而,由于非正规地区的死亡率下降较快,不平等差距随着时间的推移而缩小。这一下降的原因是疟疾和其他原因(包括败血症、艾滋病毒/艾滋病、麻疹、脑膜炎和脑炎)导致的死亡率迅速下降。对非正规地区进行改造和实施针对最贫困人口的社会政策,可能会加速瓦加杜古死亡率的整体下降。
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引用次数: 0
Smartphone GPS-Based Exposure to Greenspace and Walkability and Accelerometer-Assessed Physical Activity During Pregnancy and Early Postpartum-Evidence from the MADRES Cohort. 基于智能手机 GPS 的孕期和产后早期绿地接触、步行能力和加速计评估的体力活动--来自 MADRES 队列的证据。
IF 4.3 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-15 DOI: 10.1007/s11524-024-00903-6
Li Yi, Rima Habre, Tyler B Mason, Yan Xu, Jane Cabison, Marisela Rosales, Daniel Chu, Thomas A Chavez, Mark Johnson, Sandrah P Eckel, Theresa M Bastain, Carrie V Breton, John P Wilson, Genevieve F Dunton

A growing number of studies have associated walkability and greenspace exposure with greater physical activity (PA) in women during pregnancy. However, most studies have focused on examining women's residential environments and neglected exposure in locations outside the home neighborhood. Using 350 person-days (N = 55 participants) of smartphone global positioning system (GPS) location and accelerometer data collected during the first and third trimesters and 4-6 months postpartum from 55 Hispanic pregnant women from the Maternal and Developmental Risks from Environmental and Social Stressors (MADRES) study, we examined the day-level effect of women's exposure to walkability and greenspace on their PA outcomes during pregnancy and in the early postpartum period. Moderate-to-vigorous physical activity [MVPA] minutes per day was assessed using accelerometers. Walkability and greenspace were measured using geographic information systems (GIS) within women's daily activity spaces (i.e., places visited and routes taken) recorded using a smartphone GPS and weighted by time spent. We used a generalized linear mixed-effects model to estimate the effects of daily GPS-derived environmental exposures on day-level MVPA minutes. Results showed that women engaged in 23% more MVPA minutes on days when they had some versus no exposure to parks and open spaces in activity spaces (b = 1.23; 95%CI: 1.02-1.48). In addition, protective effects of daily greenspace and walkability exposure on MVPA were stronger in the first and third trimesters, among first-time mothers, and among women who had high pre-pregnancy body mass index (BMI) and lived in least-safe neighborhoods. Our results suggest that daily greenspace and walkability exposure are important for women's PA and associated health outcomes during pregnancy and early postpartum.

越来越多的研究表明,适宜步行的环境和绿地接触与孕期妇女更多的身体活动(PA)有关。然而,大多数研究都集中于研究女性的居住环境,而忽略了女性在家庭邻里之外的地点的接触情况。我们利用 "环境和社会压力因素对孕产妇和发育造成的风险"(MADRES)研究中收集的 55 名西班牙裔孕妇在怀孕第一和第三季度以及产后 4-6 个月期间 350 人天(N = 55 名参与者)的智能手机全球定位系统(GPS)定位和加速度计数据,研究了妇女在怀孕期间和产后早期暴露于步行环境和绿地对其 PA 结果的日级影响。每天中等强度到高强度的身体活动[MVPA]分钟数使用加速度计进行评估。使用地理信息系统(GIS)对妇女的日常活动空间(即访问过的地方和走过的路线)进行测量,这些空间是使用智能手机 GPS 记录的,并根据花费的时间进行加权。我们使用广义线性混合效应模型来估算每天从全球定位系统获取的环境暴露对全天 MVPA 分钟数的影响。结果表明,女性在接触公园和开放空间的活动时间比不接触公园和开放空间的活动时间多 23% (b = 1.23;95%CI:1.02-1.48)。此外,每天接触绿地和步行对 MVPA 的保护作用在第一胎和第三胎、初为人母以及孕前体重指数(BMI)高和居住在最不安全社区的妇女中更强。我们的研究结果表明,在怀孕期间和产后早期,每天接触绿地和步行对妇女的体育锻炼和相关健康结果非常重要。
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引用次数: 0
Summer Heat, Historic Redlining, and Neighborhood Walking among Older Adults: 2017 National Household Travel Survey. 夏季炎热、历史红线和老年人的邻里步行:2017 年全国家庭旅行调查。
IF 4.3 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-12 DOI: 10.1007/s11524-024-00892-6
Diana Mitsova, Lilah M Besser, Elaine T Le

No known studies have examined the relationships between urban heat islands, historic redlining, and neighborhood walking in older adults. We assessed whether (1) individual and neighborhood characteristics (including redlining score) differ by neighborhood summer land surface temperature (LST); (2) higher LST is associated with less neighborhood walking, and whether associations differ by historic redlining score; and (3) neighborhoods with discriminatory redlining scores have greater LSTs. We used data on 3982 ≥ 65 years old from the 2017 National Household Travel Survey. Multivariable negative binomial and linear regressions tested associations between LST z-score (comparing participant's neighborhood LST to surrounding region's LST) and self-reported neighborhood walking and the association between living in neighborhoods redlined as "definitely declining" or "hazardous" (versus "still desirable"/"best") and LST z-score. LSTs were higher for those in neighborhoods with higher area deprivation scores and more African American/Black residents. Older adults living in neighborhoods with higher summer LST z-scores had fewer minutes of neighborhood walking/day. This association seemed limited to individuals with neighborhood redlining scores of "still desirable"/"best." Neighborhood redlining scores of "definitely declining" or "hazardous" (versus "still desirable" and "best") were associated with greater neighborhood summer LSTs. Overall, these findings suggest that historically redlined neighborhoods may experience urban heat island effects more often. While older adults living in hotter neighborhoods with "still desirable" or "best" redlining scores may less often engage in neighborhood walking, those in neighborhoods with redlining scores of "definitely declining" and "hazardous" do not seem to decrease neighborhood walking with higher LSTs. Future work is needed to elucidate the impact of extreme heat on health-promoting behaviors such as walking and the types of interventions that can successfully counteract negative impacts on historically disadvantaged communities.

目前还没有研究探讨过城市热岛、历史红线和老年人邻里步行之间的关系。我们评估了:(1)个人和邻里特征(包括红线分数)是否因邻里夏季地表温度(LST)的不同而不同;(2)较高的 LST 是否与较少的邻里步行有关,相关性是否因历史红线分数的不同而不同;以及(3)具有歧视性红线分数的邻里是否具有更高的 LST。我们使用了 2017 年全国住户出行调查中 3982 名≥65 岁老人的数据。多变量负二项回归和线性回归检验了 LST z-score(将参与者所在社区的 LST 与周边地区的 LST 进行比较)与自我报告的社区步行之间的关联,以及居住在被红线划为 "肯定下降 "或 "危险"(相对于 "仍然理想"/"最佳")的社区与 LST z-score之间的关联。居住在地区贫困分数较高、非裔美国人/黑人居民较多的社区的老年人的 LST 分数较高。居住在夏季 LST z 分数较高社区的老年人每天在社区步行的时间较少。这种关联似乎仅限于邻里红线分数为 "仍然理想"/"最佳 "的个人。街区红线得分 "绝对下降 "或 "危险"(相对于 "仍然理想 "和 "最佳")与街区夏季 LST 值较高有关。总之,这些研究结果表明,历史上被划为红线的社区可能会更频繁地受到城市热岛效应的影响。虽然居住在 "仍然理想 "或 "最佳 "红线分数的较热社区的老年人可能较少参与社区步行,但居住在红线分数为 "肯定下降 "和 "危险 "的社区的老年人似乎并没有因为较高的 LST 而减少社区步行。我们需要在今后的工作中阐明极端高温对步行等促进健康行为的影响,以及能够成功抵消对历史上处于不利地位社区的负面影响的干预措施类型。
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引用次数: 0
Are Neighborhood Greenspaces Associated with Leisure-time Physical Activity? Results from ELSA-Brasil Eight-year Follow-up. 邻里绿地与闲暇时间的体育活动有关吗?ELSA-Brasil 八年跟踪调查结果。
IF 4.3 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-06 DOI: 10.1007/s11524-024-00896-2
Luciene Fátima Fernandes Almeida, Sandhi Maria Barreto, Maria Conceição Chagas Almeida, Isabela Judith Bensenor, Paulo Andrade Lotufo, Maria Del Carmen Bisi Molina, Letícia de Oliveira Cardoso, Luana Giatti

We investigated whether neighborhood greenspaces were associated with physical activity in adulthood over 3 cohort visits after considering perceived safety and neighborhood contextual factors. We also evaluated whether the association with greenspace varied by neighborhood socioeconomic status. Participants (N = 4,800) from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) residing in two Brazilian state capitals were evaluated in Visits 1 (2008-2010), 2 (2012-2014) and 3 (2017-2019). Greenspaces were categorized by quintiles of positive Normalized Difference Vegetation Index (NDVI) scores. Physical activity frequency was given by the number of visits at which participants reported moderate/vigorous physical activity (none, 1 or 2, and 3 visits). We used multinomial logistic regression. After adjustment for age, sex, education, research center, residence in slums, individuals in the 4th and 5th NDVI quintiles showed 73% higher odds of physical activity over 3 visits than those in the 1st quintile (4th quintile: 95%CI = 1.24-2.43; 5th quintile: 95%CI = 1.24-2.41). The strength of the association was attenuated after adjustment for perceived safety. After adjustment for contextual factors quantity of sidewalks and streetlights, the OR for the 4th and 5th NDVI quintiles decreased to 1.66 (95%CI = 1.18-2.33) and 1.62 (95%CI = 1.16-2.28), respectively. Finally, after including average household income per capita, the OR for physical activity in 3 visits for the 4th and 5th NDVI quintiles decreased to 1.48 (95%CI = 1.04-2.12) and 1.43 (95%CI = 1.00-2.04; p = 0.053), respectively. Greater greenspace contributed to sustained physical activity during the eight years of follow-up, indicating the potential contribution of public greenspaces to reducing health-related inequalities.

在考虑了安全感和邻里环境因素后,我们调查了邻里绿地在 3 次队列访问中是否与成年后的体育活动有关。我们还评估了绿地与邻里社会经济地位的关系是否存在差异。巴西成人健康纵向研究(ELSA-Brasil)的参与者(N = 4,800)居住在巴西的两个州府,我们对他们进行了第 1 次(2008-2010 年)、第 2 次(2012-2014 年)和第 3 次(2017-2019 年)访问评估。绿地按归一化差异植被指数(NDVI)正分数的五分位数进行分类。体育活动频率按参与者报告进行中等/剧烈体育活动的访问次数(无、1 或 2 次和 3 次)来表示。我们采用了多项式逻辑回归法。在对年龄、性别、教育程度、研究中心、贫民窟居住地等因素进行调整后,NDVI 五分位数第 4 和第 5 位的人比五分位数第 1 位的人进行 3 次体育锻炼的几率高 73%(五分位数第 4 位:95%CI = 1.24-2.43;五分位数第 5 位:95%CI = 1.24-2.41)。在对安全感进行调整后,这种关联的强度有所减弱。在对人行道和路灯数量等环境因素进行调整后,第 4 和第 5 个 NDVI 五分位数的 OR 分别降至 1.66(95%CI = 1.18-2.33)和 1.62(95%CI = 1.16-2.28)。最后,在计入人均家庭收入后,NDVI 五分位数第 4 和第 5 组的 3 次体力活动 OR 分别降至 1.48 (95%CI = 1.04-2.12) 和 1.43 (95%CI = 1.00-2.04; p = 0.053)。在八年的跟踪调查中,更多的绿色空间有助于持续的体育锻炼,这表明公共绿地在减少与健康相关的不平等方面具有潜在的贡献。
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引用次数: 0
Structural Determinants of Health and Markers of Immune Activation and Systemic Inflammation in Sexual Minority Men With and Without HIV. 感染和未感染艾滋病毒的少数性取向男性的健康结构决定因素及免疫激活和系统炎症标志物。
IF 4.3 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-01 Epub Date: 2024-06-03 DOI: 10.1007/s11524-024-00882-8
Delaram Ghanooni, Annesa Flentje, Sabina Hirshfield, Keith J Horvath, Patricia I Moreno, Audrey Harkness, Emily J Ross, Samantha E Dilworth, Savita Pahwa, Suresh Pallikkuth, Adam W Carrico

Among sexual minority men (SMM), HIV and use of stimulants such as methamphetamine are linked with immune activation and systemic inflammation. Throughout the COVID-19 pandemic, SMM encountered financial challenges and structural obstacles that might have uniquely contributed to immune dysregulation and systemic inflammation, beyond the impacts of HIV and stimulant use. Between August 2020 and February 2022, 72 SMM with and without HIV residing in South Florida enrolled in a COVID-19 prospective cohort study. Multiple linear regression analyses examined unemployment, homelessness, and history of arrest as structural correlates of soluble markers of immune activation (i.e., sCD14 and sCD163) and inflammation (i.e., sTNF-α receptors I and II) at baseline after adjusting for HIV status, stimulant use, and recent SARS-CoV-2 infection. Enrolled participants were predominantly Latino (59%), gay-identified (85%), and with a mean age of 38 (SD, 12) years with approximately one-third (38%) of participants living with HIV. After adjusting for HIV status, SARS-CoV-2 infection, and recent stimulant use, unemployment independently predicted higher levels of sCD163 (β = 0.24, p = 0.04) and sTNF-α receptor I (β = 0.26, p = 0.02). Homelessness (β = 0.25, p = 0.02) and history of arrest (β = 0.24, p = 0.04) independently predicted higher levels of sCD14 after adjusting for HIV status, SARS-CoV-2 infection, and recent stimulant use. Independent associations exist between structural barriers and immune activation and systemic inflammation in SMM with and without HIV. Future longitudinal research should further elucidate complex bio-behavioral mechanisms linking structural factors with immune activation and inflammation.

在性少数群体男性(SMM)中,艾滋病毒和兴奋剂(如甲基苯丙胺)的使用与免疫激活和全身炎症有关。在 COVID-19 大流行期间,性少数群体男性遇到了经济挑战和结构性障碍,这可能是导致免疫失调和全身炎症的独特原因,而非艾滋病毒和使用兴奋剂的影响。2020 年 8 月至 2022 年 2 月期间,居住在南佛罗里达州的 72 名感染和未感染 HIV 的 SMM 参与了 COVID-19 前瞻性队列研究。多元线性回归分析研究了失业、无家可归和被捕史与基线免疫激活可溶性标记物(即 sCD14 和 sCD163)和炎症(即 sTNF-α 受体 I 和 II)的结构相关性,并对 HIV 感染状况、兴奋剂使用和近期 SARS-CoV-2 感染进行了调整。入选者主要为拉丁裔(59%)、同性恋(85%),平均年龄为 38 岁(标准偏差为 12 岁),其中约三分之一(38%)的人感染了 HIV。在对 HIV 感染状况、SARS-CoV-2 感染和近期使用兴奋剂进行调整后,失业可独立预测较高水平的 sCD163(β = 0.24,p = 0.04)和 sTNF-α 受体 I(β = 0.26,p = 0.02)。无家可归(β = 0.25,p = 0.02)和被捕史(β = 0.24,p = 0.04)可独立预测较高水平的 sCD14,这是在调整 HIV 感染状况、SARS-CoV-2 感染和近期使用兴奋剂后得出的结果。在感染和未感染艾滋病毒的SMM患者中,结构障碍与免疫激活和全身炎症之间存在独立的关联。未来的纵向研究应进一步阐明结构因素与免疫激活和炎症之间复杂的生物行为机制。
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引用次数: 0
Urban Scaling Functions: Emission, Pollution and Health. 城市规模函数:排放、污染与健康。
IF 4.3 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-01 Epub Date: 2024-07-12 DOI: 10.1007/s11524-024-00888-2
Caterina A M La Porta, Stefano Zapperi

Urban scaling is widely used to characterize the population dependence of city indicators including greenhouse gas emission. Here we analyze the population dependence of CO 2 and PM2.5 emissions and concentrations across all European cities. Our analysis reveals considerable variations in emissions among cities of comparable population size which are not captured by conventional urban scaling. We thus characterize these fluctuations by multi-parameter scaling functions and multifractal spectral analysis. We find that the distribution of emissions and population is multifractal while that of air pollution is not, leading to non-trivial relations between emission and pollution in some large cities. We also analyze the impact of forests in curbing emission and the impact of air pollution on health. Our work provides a detailed picture of the fluctuations in the scaling of urban metabolism in Europe and suggests a general strategy that goes beyond conventional urban scaling laws.

城市规模被广泛用于描述包括温室气体排放在内的城市指标的人口依赖性。在此,我们分析了欧洲所有城市二氧化碳和 PM2.5 排放量和浓度的人口依赖性。我们的分析表明,在人口规模相当的城市之间,排放量存在相当大的差异,而传统的城市缩放方法无法捕捉到这些差异。因此,我们通过多参数缩放函数和多分形光谱分析来描述这些波动。我们发现,排放和人口的分布是多分形的,而空气污染的分布则不是,这导致一些大城市的排放和污染之间存在非三角关系。我们还分析了森林对抑制排放的影响以及空气污染对健康的影响。我们的工作提供了欧洲城市新陈代谢规模波动的详细情况,并提出了超越传统城市规模规律的一般策略。
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引用次数: 0
Who Benefits? A Mixed Methods Study Assessing Community Use of a Major Metropolitan Park During the COVID-19 Pandemic. 谁会受益?一项混合方法研究,评估 COVID-19 大流行期间大都市公园的社区使用情况。
IF 4.3 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-01 Epub Date: 2024-07-18 DOI: 10.1007/s11524-024-00886-4
Áine O'Connor, Eugen Resendiz, Leah Nason, Amy A Eyler, Ross C Brownson, Rodrigo S Reis, Ann Banchoff, Abby C King, Deborah Salvo

By providing spaces for recreation, physical activity, social gatherings, and time in nature, urban parks offer physical, mental, and social benefits to users. However, many urban residents face barriers to park use. The COVID-19 pandemic introduced new potential barriers to urban park access and use, including changes to daily life and employment, closure of park amenities and restrictions to public movement, and risk from the coronavirus itself. The mixed-methods PARCS study measured use and perceptions of a large urban park in St. Louis, Missouri before, during, and after local COVID-19 contingency measures and restrictions. We examine data from 1,157 direct observation assessments of park usership, an online survey of park users (n=561), interviews with key stakeholders (n=27), four focus groups (n=30), and a community-based participatory research sub-study (n=66) to comprehensively characterize the effects of the COVID-19 pandemic on park use. Park users who felt unsafe from the coronavirus experienced 2.65 higher odds of reducing park use. However, estimated park visits during COVID-19 contingency measures (n=5,023,759) were twice as high as post-contingency (n=2,277,496). Participants reported using the park for physical activity, recreation, time in nature, and socializing during the contingency period. Black, Hispanic/Latino, and young people were less likely to visit the park than others, suggesting an additional, disproportionate impact of the pandemic on minoritized and socioeconomically disadvantaged communities. This study highlights the role of public spaces like parks as resources for health and sites where urban health inequities can be alleviated in times of public crisis.

城市公园为人们提供了娱乐、体育活动、社交聚会和亲近大自然的空间,为使用者带来了身体、精神和社会方面的益处。然而,许多城市居民在使用公园时面临障碍。COVID-19 大流行为城市公园的进入和使用带来了新的潜在障碍,包括日常生活和就业的改变、公园设施的关闭和对公众行动的限制,以及冠状病毒本身带来的风险。PARCS 混合方法研究测量了密苏里州圣路易斯市一个大型城市公园在当地 COVID-19 应急措施和限制之前、期间和之后的使用情况和看法。我们研究了 1,157 次公园使用情况直接观察评估、公园使用者在线调查(n=561)、主要利益相关者访谈(n=27)、四个焦点小组(n=30)和一项基于社区的参与式研究子研究(n=66)的数据,以全面描述 COVID-19 大流行对公园使用的影响。因冠状病毒而感到不安全的公园使用者减少使用公园的几率要高出 2.65。然而,在 COVID-19 应急措施期间(人数=5,023,759),公园的估计访问量是应急措施后(人数=2,277,496)的两倍。据参与者报告,在应急期间,他们使用公园进行体育活动、娱乐、亲近大自然和社交活动。与其他人相比,黑人、西班牙裔/拉丁美洲人和年轻人去公园的可能性较低,这表明大流行病对少数民族和社会经济条件较差的社区造成了额外的、不成比例的影响。这项研究强调了公园等公共场所作为健康资源的作用,以及在公共危机时期可以缓解城市健康不平等的场所。
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引用次数: 0
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Journal of Urban Health-Bulletin of the New York Academy of Medicine
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