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Arbovirology and Cold War Collaborations: A Transnational History of the Tick-borne Encephalitis Vaccine, 1930-1980. Arbovirology and Cold War Collaborations:蜱传脑炎疫苗的跨国历史,1930-1980 年》。
IF 0.9 3区 哲学 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-08-06 DOI: 10.1093/jhmas/jrad054
Anna Mazanik

This article analyzes the history of immunization against tick-borne encephalitis (TBE) and specifically the processes that led to the creation and application of TBE vaccines in the Soviet Union and Austria. Rather than presenting the development of TBE vaccines from the perspective of national scientific schools, the article investigates their history as a transnational project, focusing on the connections among the Soviet Union, Czechoslovakia, Austria, the United States, and the United Kingdom. It argues that biomedical research on TBE was profoundly intertwined with political and military agendas and depended on civil international cooperation as well as Soviet, American, and British military concerns, infrastructures and funding. The article consists of four parts that discuss (1) the identification of the TBE virus and the creation of the first TBE vaccine in the Soviet Union in the 1930s; (2) the internationalization of TBE research and vaccine development in the 1940s-1960s; (3) the history of TBE research and virology in Austria in the 1930s-1960s and the role of the US military funding; and (4) the cooperation of Austrian virologist Christian Kunz with the Microbiological Research Establishment Porton Down in the UK leading to the development of the Austrian/British vaccine against TBE in the 1970s.

本文分析了蜱传脑炎(TBE)免疫接种的历史,特别是苏联和奥地利创造和应用 TBE 疫苗的过程。文章没有从国家科学流派的角度介绍 TBE 疫苗的发展,而是将其作为一个跨国项目来研究,重点关注苏联、捷克斯洛伐克、奥地利、美国和英国之间的联系。文章认为,有关 TBE 的生物医学研究与政治和军事议程密切相关,依赖于民间国际合作以及苏联、美国和英国的军事关切、基础设施和资金。文章由四个部分组成,分别讨论:(1) 20 世纪 30 年代苏联对 TBE 病毒的鉴定和第一种 TBE 疫苗的研制;(2) 20 世纪 40 年代至 60 年代 TBE 研究和疫苗研制的国际化;(3) TBE 的历史;(3) 20 世纪 30 年代至 60 年代奥地利的结核病研究和病毒学历史以及美国军方资助的作用;以及 (4) 奥地利病毒学家 Christian Kunz 与英国微生物研究机构 Porton Down 的合作,促成了 20 世纪 70 年代奥地利/英国结核病疫苗的开发。
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引用次数: 0
A Disputed Hegemony: Negotiating Neurosurgical Patient Care in the Netherlands, 1930-1952. 有争议的霸权:1930-1952年荷兰神经外科病人护理的谈判。
IF 0.9 3区 哲学 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-08-06 DOI: 10.1093/jhmas/jrae014
Bart Lutters

The emergence of the neurosurgical patient as a novel clinical entity in the Netherlands was marked by a lingering conflict between neurologists and neurosurgeons, in which both types of specialists sought to assume the clinical and institutional leadership of neurosurgical patient care. In the 1920s and 1930s, neurologists had facilitated the establishment of the first generation of neurosurgeons in the country, and in the process, had managed to clinically and institutionally subordinate neurosurgery to neurology. As the demand for neurosurgical patient care grew, the neurosurgeons began to challenge this hegemonic relationship. The neurologists, however, were unwilling to give up their control, fearing that they would be bypassed in the diagnosis of patients eligible to neurosurgery. These conflicting aims and interests resulted in an intricate demarcation battle, in which the boundary work between neurologists and neurosurgeons was directly played out at the local workplace and at the meetings of the Study Club for Neuro-Surgery, and indirectly at various other sites of contestation, such as medical journals and academic lecture halls, as both parties sought to rally external stakeholders to their cause. During these negotiations, local, national, and international forces increasingly intertwined to shape the particular organization of Dutch neurosurgery in the middle of the twentieth century. By analyzing this multilayered demarcation process, this article draws attention to the complexity of medical boundary work, and to the way in which, despite pervasive international influences, specialist practice was ultimately negotiated at the local and national levels.

在荷兰,神经外科病人作为一个新的临床实体出现时,神经内科医师和神经外科医师之间的冲突始终存在,这两类专家都试图在神经外科病人护理的临床和机构方面占据领导地位。在二十世纪二三十年代,神经科医生促成了荷兰第一代神经外科医生的诞生,并在这一过程中成功地使神经外科在临床和制度上从属于神经内科。随着神经外科病人护理需求的增长,神经外科医生开始挑战这种霸权关系。然而,神经科医生不愿放弃他们的控制权,担心他们在诊断符合神经外科手术条件的病人时会被绕过。这些相互冲突的目标和利益导致了一场错综复杂的划界之战,在这场战争中,神经学家和神经外科医生之间的划界工作直接在当地工作场所和神经外科研究俱乐部的会议上展开,也间接地在医学期刊和学术报告厅等其他各种争夺场所进行,双方都试图拉拢外部利益相关者支持自己的事业。在这些谈判过程中,地方、国家和国际力量日益交织在一起,形成了二十世纪中叶荷兰神经外科的特殊组织形式。通过分析这一多层次的划界过程,本文提请人们注意医学边界工作的复杂性,以及尽管国际影响无处不在,但专科实践最终还是在地方和国家层面进行谈判的方式。
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引用次数: 0
Silences and Omissions in Reporting Epidemics in Russian and Soviet Prisons, 1890-2021. 1890-2021 年俄罗斯和苏联监狱流行病报告中的沉默与遗漏。
IF 0.9 3区 哲学 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-08-06 DOI: 10.1093/jhmas/jrad047
Mikhail Nakonechnyi, Judith Pallot

Penitentiary systems serve as breeding grounds for all kinds of diseases. Drawing upon new archival materials, this article examines the history of the management and reporting of epidemics in the Russian prison system from the late Imperial period to the present day. We use the case studies of cholera (1892-1893), typhus (1932-1933), and pulmonary tuberculosis (the 1990s) to examine how the general political and social conjuncture at different times affected the response of prison authorities to epidemics to show that, notwithstanding major shifts in society and polity, there was continuity in the management of epidemics by prison authorities in the long twentieth century. However, there were fundamental discrepancies in the way late Imperial, Soviet, and post-Soviet Russia reported epidemiological emergencies in prisons. We argue that Russia's tumultuous past has reinforced the tendency among the Russian penal administration towards a lack of transparency that has persisted to the present day, in relation to the latest, COVID-19, epidemic.

监狱系统是各种疾病的滋生地。本文利用新的档案资料,研究了从帝国晚期至今俄罗斯监狱系统管理和报告流行病的历史。我们通过对霍乱(1892-1893 年)、斑疹伤寒(1932-1933 年)和肺结核(20 世纪 90 年代)的案例研究,探讨了不同时期的总体政治和社会环境如何影响监狱当局对流行病的反应,从而表明,尽管社会和政体发生了重大变化,但在漫长的 20 世纪,监狱当局对流行病的管理仍具有连续性。然而,帝国晚期、苏维埃时期和后苏维埃时期的俄罗斯在报告监狱流行病紧急情况的方式上存在根本差异。我们认为,俄罗斯动荡的过去加剧了俄罗斯刑事管理部门缺乏透明度的趋势,这种趋势一直持续到今天,与最近的 COVID-19 疫情有关。
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引用次数: 0
Treating Delinquent and Feebleminded Juveniles at the Beloit Industrial School for Girls in Early Twentieth-Century Kansas. 二十世纪初堪萨斯州贝洛伊特女子工业学校对少年犯和智力低下者的治疗》(Treatmenting Delinquent and Feebleminded Juveniles at the Beloit Industrial School for Girls in Early Twentieth-Century Kansas.
IF 0.9 3区 哲学 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-08-06 DOI: 10.1093/jhmas/jrad046
Heather L McCrea

This study explores the troubling and unintended consequences of public health efforts to address the problem of juvenile delinquency and feeblemindedness. Health care professionals, superintendents, and other authority figures equated undesirable juvenile behaviors such as keeping "bad company" or "falling in with the wrong crowd," truancy, and petty theft with poor breeding, low intelligence, and inheritable criminal tendencies. This article interrogates historical documentation culled from the Kansas State Historical Society (KSHS) and focuses on a few specific cases to reveal the ways a patriarchal political and medical state system both protected and alienated young woman accused of a myriad of behavior issues including delinquency, incorrigibility, and feeblemindedness. I highlight the lives of juvenile women sentenced to the Beloit Industrial School for Girls not simply to better understand an isolated period in United States history but also reproduction. The broader implications of the narratives of girls housed at the Beloit Industrial School for Girls throughout the first half of the twentieth century in Kansas reveal troubling and unintended consequences of public health efforts to fix the problems of delinquency, contagion, and the generational inheritance of undesirable characteristics.

本研究探讨了公共卫生工作在解决青少年犯罪和弱智问题时所产生的令人不安的意外后果。卫生保健专业人员、学监和其他权威人士将青少年的不良行为,如与 "坏伙伴 "或 "误入歧途"、逃学和小偷小摸等,等同于教养不良、智力低下和遗传性犯罪倾向。本文对堪萨斯州历史学会(Kansas State Historical Society,KSHS)收集的历史文献进行了研究,并重点关注了几个具体案例,揭示了父权制的政治和医疗国家体系是如何保护和疏远被指控有各种行为问题(包括犯罪、不可救药和智力低下)的年轻女性的。我强调被判刑到贝洛伊特女子工业学校的少女的生活,不仅仅是为了更好地理解美国历史上一个孤立的时期,也是为了再现历史。在堪萨斯州整个 20 世纪上半叶,贝洛伊特女子工业学校收容的女孩的叙述所产生的广泛影响揭示了公共卫生努力解决犯罪、传染和不良特征代代相传等问题所带来的令人不安和意想不到的后果。
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引用次数: 0
Confronting Medical Diploma Mills: State Licensing Boards, Legislatures, and the Limits of Medical Authority in the 1920s. 对抗医学文凭制造厂:20 世纪 20 年代的州执照委员会、立法机构和医疗权力的限制》。
IF 0.9 3区 哲学 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-07-11 DOI: 10.1093/jhmas/jrae012
Toby A Appel

In the standard story of the rise of professional authority in medicine in the 1920s, state medical licensing boards were partners in a coalition, led by the American Medical Association, to radically improve medical education. Boards obtained state laws that limited admission to licensing examinations to graduates of schools approved by the AMA, thus bringing about the rapid demise of low-quality schools by about 1925. The reality at the state level was quite different, however. Medical examining boards containing homeopaths, eclectics, and sometimes osteopaths could be far from reliable partners. Passing laws to benefit the medical profession was exceedingly difficult and dependent on local medical politics. Through the lens of a major medical diploma mill scandal revealed by a journalist in 1923, this paper examines reform efforts in three states greatly affected by the scandal: Missouri, where the scandal originated, Connecticut, and Massachusetts. In each of these states, graduates of low-quality schools as well as fake doctors from diploma mills were able to take a state examination and practice. This paper argues that the AMA, far from being the major player in the elimination of inadequate schools, could set standards but had to stay on the sidelines.

在 20 世纪 20 年代医学专业权威崛起的标准故事中,各州医学执照颁发委员会是美国医学会领导的联盟中的合作伙伴,旨在从根本上改善医学教育。委员会获得了州法律,规定只有经美国医学会批准的学校的毕业生才能参加执照考试,从而使低质量的学校在 1925 年左右迅速消亡。然而,州一级的实际情况却大相径庭。包含顺势疗法者、折衷主义者,有时还有整骨疗法者的医学考试委员会可能远非可靠的合作伙伴。要通过有利于医学界的法律极其困难,而且还要依赖当地的医学政治。本文以 1923 年一名记者揭露的一起重大医学文凭工厂丑闻为视角,探讨了受该丑闻严重影响的三个州的改革努力:这三个州分别是:丑闻的发源地密苏里州、康涅狄格州和马萨诸塞州。在这三个州中,劣质学校的毕业生以及文凭工厂的假医生都可以参加州考试并执业。本文认为,美国医学会远非消除不合格学校的主要参与者,它可以制定标准,但却不得不置身事外。
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引用次数: 0
The Figure of the Staggering Rat: Reading Colonial Outbreak Narratives Against the Grain of “Virus Hunting” 蹒跚鼠的形象:从 "猎杀病毒 "的角度解读殖民地疫情叙事
IF 0.5 3区 哲学 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-05-03 DOI: 10.1093/jhmas/jrae004
Christos Lynteris
The image of dazed, plague-infected rats coming out of their nests and performing a pirouette in front of the surprised eyes of humans before dying is one well-known to us through Albert Camus’s The Plague (1947). This article examines the historical roots of this image and its emergence in French missionary narratives about plague outbreaks in the Chinese province of Yunnan in the 1870s on the eve of the Third Plague Pandemic. Showing that accounts of the “staggering rat” were not meant as naturalist observations of a zoonotic disease, as is generally assumed by historians, but as a cosmological, end-of-the-world narrative with a colonial agenda, the article argues for an approach to historical accounts of epidemics that does not succumb to the current trend of “virus hunting” in the archive, but rather takes colonial outbreak narratives ethnographically seriously.
在阿尔贝-加缪的《鼠疫》(1947 年)中,我们熟知这样一个形象:被鼠疫感染的老鼠茫然地从巢穴中走出来,在人类惊讶的目光中表演回旋,然后死去。本文研究了这一形象的历史根源,以及它在 19 世纪 70 年代第三次鼠疫大流行前夕法国传教士对中国云南鼠疫爆发的描述中的出现。文章指出,关于 "蹒跚的老鼠 "的描述并不像历史学家普遍认为的那样是对人畜共患疾病的自然主义观察,而是一种带有殖民议程的宇宙论、世界末日叙事,因此文章主张对流行病的历史描述采取一种不屈服于当前档案中 "病毒猎杀 "趋势的方法,而是从人种学角度认真对待殖民疫情叙事。
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引用次数: 0
Pandemic Forms 大流行病形式
IF 0.5 3区 哲学 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-05-03 DOI: 10.1093/jhmas/jrae003
Lakshmi Krishnan
Narrative structures, though invisible to the naked eye, guide our understanding of pandemics. Like curves and graphs, we can plot them, identify their patterns and organizing principles. These structures act upon our understanding of social and biological events just as much as the rhythms of viral replication and mutation. They order not only themselves but also social and health outcomes. This essay uses narrative precision to expand beyond Charles Rosenberg’s influential dramaturgic model and develops new pandemic forms, scaled from the level of an individual line break to the multi-part series: Arc, a form of sequence. Cycle, a form of repetition. Sequel, a form of elongation. Caesura, a form of break. It investigates the potentialities and limitations of these forms, how they intersect, collide, and contradict, and how analysis of these interactions contributes to a deeper understanding of pandemics, their effects, and the diverse perspectives defining their structures. In doing so, it prototypes how literary methods offer conceptual frameworks for pandemic historiography and how a transdisciplinary, medical humanities analysis produces novel understandings at the intersection of health, culture, and society.
叙事结构虽然肉眼不可见,却能引导我们理解大流行病。就像曲线和图表一样,我们可以绘制它们,识别它们的模式和组织原则。这些结构与病毒复制和变异的节奏一样,影响着我们对社会和生物事件的理解。它们不仅使自身有序化,也使社会和健康结果有序化。本文利用叙事的精确性,超越查尔斯-罗森伯格(Charles Rosenberg)极具影响力的戏剧模式,发展出新的流行病形式,从单个断句到多部分系列:弧线,一种序列形式。循环,一种重复形式。接续,一种拉长形式。Caesura, 一种断句形式。它研究了这些形式的潜力和局限性,它们是如何交叉、碰撞和矛盾的,以及对这些相互作用的分析如何有助于加深对流行病、其影响以及定义其结构的不同观点的理解。在此过程中,该书展示了文学方法如何为大流行病史学提供概念框架,以及跨学科的医学人文分析如何在健康、文化和社会的交叉点上产生新的理解。
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引用次数: 0
Convenient Frailty: Medical Contestations of Asthma and Hay Fever in African Americans in Late Nineteenth-Century America. 便利的虚弱:十九世纪晚期美国黑人哮喘和花粉热的医学争议》(Medical Contestations of Asthma and Hay Fever in African Americans in Late Nineteenth-Century America)。
IF 0.5 3区 哲学 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-04-02 DOI: 10.1093/jhmas/jrad045
Ijeoma B Kola

Post-Emancipation medical and social science scholars extensively theorized Black susceptibility to illness, disease, and death. Most studies of late nineteenth-century medical ideas about the relationship between race and disease have highlighted the construction of medical beliefs that associated Black physical weakness with a proclivity to ill health. This study presents an alternate narrative, one where certain diseases - asthma and hay fever - reflected an opposing racialized understanding of disease that instead centered on White frailty. Based on an examination of turn-of-the-century asthma and hay fever medical literature produced by George Miller Beard, the professionalization of the United States Hay Fever Association, and the publication and dismissal of the first recorded case of asthma in an African American man in 1884, this article argues that late nineteenth-century asthma and hay fever physicians, who themselves often suffered from the conditions, defined the typical asthma patient along racial lines to protect the exclusivity of their own professional and social identities. As a result, asthma and hay fever in Black communities, particularly in the North, where asthma and hay fever scholars primarily lived and worked, remained obscured and untreated until the mid-twentieth century.

解放后的医学和社会科学学者对黑人易患病、易生病和易死亡进行了广泛的理论研究。对十九世纪末有关种族与疾病关系的医学观点的大多数研究都强调了将黑人身体虚弱与易患疾病联系起来的医学观念的构建。本研究提出了另一种说法,即某些疾病--哮喘和花粉热--反映了对疾病的相反的种族化理解,而这种理解的核心是白人的虚弱。基于对乔治-米勒-比尔德(George Miller Beard)在世纪之交撰写的哮喘和花粉热医学文献、美国花粉热协会的专业化、1884 年第一例记录在案的非裔美国人哮喘病例的发表和驳回的研究,本文认为,19 世纪晚期的哮喘和花粉热医生(他们自己也常常患有这种疾病)根据种族界限定义典型的哮喘患者,以保护他们自己的专业和社会身份的排他性。因此,黑人社区的哮喘和花粉症,尤其是哮喘和花粉症学者主要生活和工作的北方地区的哮喘和花粉症,直到二十世纪中叶仍被掩盖,得不到治疗。
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引用次数: 0
"A Much Wider Field in Which to Operate": Early Black Women Physicians in Public Health. "更广阔的工作领域":早期公共卫生领域的黑人女医师。
IF 0.5 3区 哲学 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-04-02 DOI: 10.1093/jhmas/jrad048
Margaret Vigil-Fowler, Sukumar Desai

In a profession shaped by Whiteness and masculinity, the few Black women physicians who earned medical degrees prior to the Second World War found some of their rare professional opportunities in public health. Though their choices were often constrained by racism and sexism, they embraced public health work as a means of carrying out their "mission" in marginalized communities and as a way of practicing medicine with a more expansive definition than treating individual patients or illnesses. Black women physicians shaped public health by creating unique programming to meet the needs of the communities they served, including mobile health clinics and community health weeks. The first Black women physicians who worked in public health in the nineteenth and early twentieth centuries applied the new tool of public health "vital" statistics to Black lives and questioned the limits of their utility when created by White practitioners with racial biases. In the 1930s, some Black women physicians began earning some of the first master's degrees in public health, just as the field was beginning to professionalize. Throughout the twentieth century, Black women physicians pioneered community health programming and, though born from exclusionary policies that limited where they could practice, experimented with alternative clinical spaces, even as the hospital and laboratory became the primary sites of medicine for White clinicians. By embracing public health, Black women physicians shaped the field and used it as a tool to address racial health disparities in the communities they served, acting on their belief that Black health could be improved, thereby contesting notions of biological inferiority.

在一个由白人和男性气质塑造的职业中,第二次世界大战前获得医学学位的少数黑人女医生在公共卫生领域找到了一些难得的职业机会。尽管她们的选择常常受到种族主义和性别歧视的限制,但她们还是接受了公共卫生工作,将其作为在边缘化社区履行 "使命 "的一种手段,以及作为一种行医方式,其定义比治疗个别病人或疾病更为宽泛。黑人女医生通过制定独特的计划来满足她们所服务社区的需求,包括流动诊所和社区卫生周,从而塑造了公共卫生。十九世纪和二十世纪初,第一批从事公共卫生工作的黑人女医生将公共卫生 "生命 "统计这一新工具应用于黑人的生活,并质疑由带有种族偏见的白人开业医生创建的这些统计的实用性局限性。20 世纪 30 年代,一些黑人女医生开始获得首批公共卫生硕士学位,当时该领域正开始走向专业化。在整个 20 世纪,黑人女医生开创了社区卫生计划,尽管她们的执业地点受到排斥性政策的限制,但她们还是尝试了其他临床空间,即使医院和实验室成为白人临床医生的主要医疗场所。通过拥抱公共卫生,黑人女医生塑造了这一领域,并将其作为一种工具来解决她们所服务社区的种族健康差异问题,她们坚信黑人的健康状况可以得到改善,从而对生物劣等的观念提出了质疑。
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引用次数: 0
Joseph E. Murray's Struggle to Transplant Kidneys: Failure, Individuality, and Plastic Surgery, 1950-1965. 约瑟夫-E.-默里的肾移植奋斗史:失败、个性与整形外科,1950-1965 年。
IF 0.5 3区 哲学 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-04-02 DOI: 10.1093/jhmas/jrad042
Hyung Wook Park

This paper offers a historical analysis of the American plastic surgeon and Nobel laureate Joseph E. Murray's kidney transplantation. After succeeding in the first kidney transplantation between monozygotic twins in 1954, he transplanted kidneys between genetically distinct people after X-radiation and immunosuppressants. Amid these achievements, however, Murray encountered numerous failures, which he thought were closely intertwined with each patient's physiological and pathological individuality. As he appropriated his expertise in plastic surgery for kidney transplantation, this individuality became a major issue that he had to cope with in his efforts to avoid failures. To him, kidney transplantation could fail because of each individual's immunological barrier or constitutional singularity that could engender unexpected complications. Although he could neither explain nor control many of these failures, I argue that his unsuccessful work and patient individuality played multiple roles in shaping his operations as a plastic surgeon. They structured the path of his surgical research, made sense of it, defended him from criticism, and formed the way that he presented the results of his work with an immunological implication. Consequently, Murray, with little scientific training, articulated an important dimension of immunological tolerance relevant to clinical settings.

本文对美国整形外科医生、诺贝尔奖获得者约瑟夫-穆雷(Joseph E. Murray)的肾移植手术进行了历史分析。继 1954 年首次在单卵双胞胎之间成功进行肾脏移植后,他又在 X 射线和免疫抑制剂作用下在不同基因的人之间进行了肾脏移植。然而,在取得这些成就的同时,莫里也遇到了无数次失败,他认为这些失败与每个病人的生理和病理个体性密切相关。当他把自己在整形外科方面的专长用于肾脏移植时,这种个体性就成了他在努力避免失败时必须应对的一个重要问题。在他看来,肾脏移植可能会失败,因为每个人的免疫屏障或体质奇异,可能会产生意想不到的并发症。虽然他无法解释也无法控制其中的许多失败,但我认为,他的不成功工作和病人的个性在塑造他作为整形外科医生的手术中发挥了多重作用。这些因素构建了他的外科研究之路,让他的研究更有意义,使他免受批评,并形成了他展示具有免疫学意义的工作成果的方式。因此,默里在没有接受过什么科学训练的情况下,阐明了与临床有关的免疫耐受的一个重要方面。
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引用次数: 0
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