Pub Date : 2026-01-01DOI: 10.1016/j.echo.2025.07.017
Luigi P. Badano MD, PhD , Denisa Muraru MD, PhD
{"title":"Evolving Paradigms in Quantifying Functional Tricuspid Regurgitation: The Doppler Shape Dimension","authors":"Luigi P. Badano MD, PhD , Denisa Muraru MD, PhD","doi":"10.1016/j.echo.2025.07.017","DOIUrl":"10.1016/j.echo.2025.07.017","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"39 1","pages":"Pages 55-57"},"PeriodicalIF":6.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.echo.2025.10.001
Julien Dreyfus MD, PhD , David Messika-Zeitoun MD, PhD
{"title":"Tricuspid Regurgitation Grading: Time to Harmonization","authors":"Julien Dreyfus MD, PhD , David Messika-Zeitoun MD, PhD","doi":"10.1016/j.echo.2025.10.001","DOIUrl":"10.1016/j.echo.2025.10.001","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"39 1","pages":"Pages 68-70"},"PeriodicalIF":6.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145276298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"39 2","pages":"Pages 179-187"},"PeriodicalIF":6.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147080132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"39 2","pages":"Pages 220-222"},"PeriodicalIF":6.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147080135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"39 2","pages":"Pages A13-A14"},"PeriodicalIF":6.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147097066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"39 1","pages":"Pages 99-106"},"PeriodicalIF":6.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146460656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"39 1","pages":"Pages 80-88"},"PeriodicalIF":6.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146460659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"39 1","pages":"Pages 15-24"},"PeriodicalIF":6.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146460665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mitral valve prolapse affects approximately 2.5% of the population and represents the most common cause of primary mitral regurgitation. Mitral regurgitation is related to increased leaflet size, prolapse asymmetry, long clefts, calcification, and restricted leaflet motion. Chordal abnormalities, including increased length and rupture, also play a role. Mitral valve prolapse is also recognized as an important cause of ventricular arrhythmias and sudden arrhythmic death. Patients with arrhythmic mitral valve prolapse commonly exhibit an echocardiographic phenotype characterized by thick, long mitral leaflets with multisegment bileaflet prolapse and mitral annular disjunction, with or without significant mitral regurgitation. This review discusses the pathophysiology and echocardiographic features of these abnormalities.
{"title":"Echocardiographic and Pathophysiologic Insights Into Mitral Regurgitation, Mitral Annular Disjunction, and Ventricular Arrhythmias in Patients with Mitral Valve Prolapse","authors":"Jeffrey J. Silbiger MD, Oksana Marchenko MD, PhD, Lucy Safi DO, Priya Panday MD","doi":"10.1016/j.echo.2025.08.014","DOIUrl":"10.1016/j.echo.2025.08.014","url":null,"abstract":"<div><div>Mitral valve prolapse affects approximately 2.5% of the population and represents the most common cause of primary mitral regurgitation. Mitral regurgitation is related to increased leaflet size, prolapse asymmetry, long clefts, calcification, and restricted leaflet motion. Chordal abnormalities, including increased length and rupture, also play a role. Mitral valve prolapse is also recognized as an important cause of ventricular arrhythmias and sudden arrhythmic death. Patients with arrhythmic mitral valve prolapse commonly exhibit an echocardiographic phenotype characterized by thick, long mitral leaflets with multisegment bileaflet prolapse and mitral annular disjunction, with or without significant mitral regurgitation. This review discusses the pathophysiology and echocardiographic features of these abnormalities.</div></div>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"39 1","pages":"Pages 107-119"},"PeriodicalIF":6.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.echo.2025.09.017
Lytfi Krasniqi MD , Christian Juhl Terkelsen MD, DMSc, PhD , Henrik Nissen MD, PhD , Philip Freeman MD, PhD , Christian Alcaraz Frederiksen MD, PhD , Henrik Vase MD, PhD , Kristian Hejlesen RN , Christian Byskov Fur MD , Troels Thim MD, PhD , Ashkan Eftekhari MD, PhD , Frederik Uttenthal MD , Julia Ellert MD, PhD , Nils Sofus Borg Mogensen MD, PhD , Amal Haujir MD , Evald Høj Christiansen MD, PhD , Jordi Sanchez Dahl MD, DMSc, PhD
Objective
The aim of this study was to study the impact of flow status on effective orifice area (EOA) in patients treated with the balloon-expandable Myval and Sapien transcatheter heart valves (THVs).
Methods
We collected the core laboratory-measured EOA, mean and peak gradients, Doppler velocity index (DVI), and stroke volume index (SVi) from the 30-day echocardiograms in patients treated with the balloon-expandable Myval and Sapien THVs in the COMPARE-TAVI 1 trial. Patients were stratified according to flow into low flow (SVi <35 mL/m2), normal flow (SVi 35-50 mL/m2), and high flow (SVi >50 mL/m2).
Results
A total of 1,031 patients were included in COMPARE-TAVI 1. Myval THVs (20.0-32.0 mm) exhibited overall higher mean EOA and lower mean gradients (1.99 ± 0.55 cm2, 9.46 ± 3.84 mm Hg) compared to Sapien THVs (20-29 mm; 1.81 ± 0.56 cm2, 11.47 ± 4.47 mm Hg). Compared to normal-flow patients, low-flow patients exhibited smaller EOA (P < .001) and lower DVI (P < .001) in all valve sizes irrespective of THV platform, while high-flow patients had larger EOA (P < .001) and higher DVI (P < .001). Female sex was associated with lower stroke volume, resulting in lower mean and peak gradients independent of valve size and platform (P < .001).
Conclusion
The study indicates that EOA may be underestimated after TAVI in patients with low-flow status, which can impact the assessment of prosthesis-patient mismatch.
{"title":"Impact of Flow Status on Effective Orifice Area in Transcatheter Heart Valves: A COMPARE-TAVI 1 Substudy","authors":"Lytfi Krasniqi MD , Christian Juhl Terkelsen MD, DMSc, PhD , Henrik Nissen MD, PhD , Philip Freeman MD, PhD , Christian Alcaraz Frederiksen MD, PhD , Henrik Vase MD, PhD , Kristian Hejlesen RN , Christian Byskov Fur MD , Troels Thim MD, PhD , Ashkan Eftekhari MD, PhD , Frederik Uttenthal MD , Julia Ellert MD, PhD , Nils Sofus Borg Mogensen MD, PhD , Amal Haujir MD , Evald Høj Christiansen MD, PhD , Jordi Sanchez Dahl MD, DMSc, PhD","doi":"10.1016/j.echo.2025.09.017","DOIUrl":"10.1016/j.echo.2025.09.017","url":null,"abstract":"<div><h3>Objective</h3><div>The aim of this study was to study the impact of flow status on effective orifice area (EOA) in patients treated with the balloon-expandable Myval and Sapien transcatheter heart valves (THVs).</div></div><div><h3>Methods</h3><div>We collected the core laboratory-measured EOA, mean and peak gradients, Doppler velocity index (DVI), and stroke volume index (SVi) from the 30-day echocardiograms in patients treated with the balloon-expandable Myval and Sapien THVs in the COMPARE-TAVI 1 trial. Patients were stratified according to flow into low flow (SVi <35 mL/m<sup>2</sup>), normal flow (SVi 35-50 mL/m<sup>2</sup>), and high flow (SVi >50 mL/m<sup>2</sup>).</div></div><div><h3>Results</h3><div>A total of 1,031 patients were included in COMPARE-TAVI 1. Myval THVs (20.0-32.0 mm) exhibited overall higher mean EOA and lower mean gradients (1.99 ± 0.55 cm<sup>2</sup>, 9.46 ± 3.84 mm Hg) compared to Sapien THVs (20-29 mm; 1.81 ± 0.56 cm<sup>2</sup>, 11.47 ± 4.47 mm Hg). Compared to normal-flow patients, low-flow patients exhibited smaller EOA (<em>P</em> < .001) and lower DVI (<em>P</em> < .001) in all valve sizes irrespective of THV platform, while high-flow patients had larger EOA (<em>P</em> < .001) and higher DVI (<em>P</em> < .001). Female sex was associated with lower stroke volume, resulting in lower mean and peak gradients independent of valve size and platform (<em>P</em> < .001).</div></div><div><h3>Conclusion</h3><div>The study indicates that EOA may be underestimated after TAVI in patients with low-flow status, which can impact the assessment of prosthesis-patient mismatch.</div></div>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"39 1","pages":"Pages 80-88"},"PeriodicalIF":6.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145240506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号