Pub Date : 2026-03-01Epub Date: 2026-03-03DOI: 10.1016/j.echo.2026.01.002
{"title":"Continuing Education and Meeting Calendar","authors":"","doi":"10.1016/j.echo.2026.01.002","DOIUrl":"10.1016/j.echo.2026.01.002","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"39 3","pages":"Page A11"},"PeriodicalIF":6.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147414327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2025-10-11DOI: 10.1016/j.echo.2025.09.021
Alexandra Mihai MD, Tommaso Recchioni MD, Giovanna Manzi MD, PhD, Carmine Dario Vizza MD, PhD
{"title":"Could Sex Differences Refine Risk Stratification in Pulmonary Hypertension?","authors":"Alexandra Mihai MD, Tommaso Recchioni MD, Giovanna Manzi MD, PhD, Carmine Dario Vizza MD, PhD","doi":"10.1016/j.echo.2025.09.021","DOIUrl":"10.1016/j.echo.2025.09.021","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"39 3","pages":"Pages 323-324"},"PeriodicalIF":6.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145287571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vascular remodeling, which occurs with normal aging and several pathological states, has emerged as a critical factor in assessing cardiovascular health in children. Changes in vascular structure, stiffness, and function have been shown to be associated with different diseases in children and adolescents, including metabolic syndrome, congenital heart disease, and childhood cancer. However, there is a lack of data on the ability of these vascular parameters to predict outcomes and guide therapy in the pediatric population. This paper provides an overview of the physiological principles related to pediatric vascular health and the available noninvasive methods for the measurement of arterial structure, stiffness, and function. The normal variation of these parameters during childhood and their clinical relevance in pathological conditions are discussed, with an emphasis on current knowledge gaps and the need for future research.
{"title":"Noninvasive Methods to Assess Vascular Health in Children and Adolescents: Current State-of-the-Art and Future Perspectives","authors":"Raphael Joye MD , Nairy Khodabakhshian PhD , Emmanuelle Fournier MD , Wei Hui MD , Cheryl Fackoury RDSC , Alice Pozza MD , Josh Gopaul MSc , Olivier Villemain MD, PhD , Barbara Cifra MD , Vitor Guerra MD, PhD , Luc L. Mertens MD, PhD","doi":"10.1016/j.echo.2025.09.003","DOIUrl":"10.1016/j.echo.2025.09.003","url":null,"abstract":"<div><div>Vascular remodeling, which occurs with normal aging and several pathological states, has emerged as a critical factor in assessing cardiovascular health in children. Changes in vascular structure, stiffness, and function have been shown to be associated with different diseases in children and adolescents, including metabolic syndrome, congenital heart disease, and childhood cancer. However, there is a lack of data on the ability of these vascular parameters to predict outcomes and guide therapy in the pediatric population. This paper provides an overview of the physiological principles related to pediatric vascular health and the available noninvasive methods for the measurement of arterial structure, stiffness, and function. The normal variation of these parameters during childhood and their clinical relevance in pathological conditions are discussed, with an emphasis on current knowledge gaps and the need for future research.</div></div>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"39 3","pages":"Pages 280-293"},"PeriodicalIF":6.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2025-11-03DOI: 10.1016/j.echo.2025.10.017
Hyun-Jung Lee MD, PhD, Geu-Ru Hong MD, PhD, Chi Young Shim MD, PhD
{"title":"Reply to “Renal Dysfunction, Arterial Stiffness, and the Interpretation of ‘Global Afterload’ in Moderate Aortic Stenosis – What’s Old is New Again”","authors":"Hyun-Jung Lee MD, PhD, Geu-Ru Hong MD, PhD, Chi Young Shim MD, PhD","doi":"10.1016/j.echo.2025.10.017","DOIUrl":"10.1016/j.echo.2025.10.017","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"39 3","pages":"Pages 327-329"},"PeriodicalIF":6.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145453931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2025-11-07DOI: 10.1016/j.echo.2025.10.018
Offdan Narvaez-Guerra MD, Evan Offord MD, David Gerson MD, Timothy P. Fitzgibbons MD, PhD, Matthew Parker MD, Gerard Aurigemma MD
{"title":"The Effects of Foreshortening on the Optimal Intersection Angle between the Apical 4-Chamber and Apical 2-Chamber Views","authors":"Offdan Narvaez-Guerra MD, Evan Offord MD, David Gerson MD, Timothy P. Fitzgibbons MD, PhD, Matthew Parker MD, Gerard Aurigemma MD","doi":"10.1016/j.echo.2025.10.018","DOIUrl":"10.1016/j.echo.2025.10.018","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"39 3","pages":"Pages 316-317"},"PeriodicalIF":6.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145483592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2026-03-03DOI: 10.1016/S0894-7317(26)00043-X
{"title":"Information for Readers","authors":"","doi":"10.1016/S0894-7317(26)00043-X","DOIUrl":"10.1016/S0894-7317(26)00043-X","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"39 3","pages":"Pages A7-A8"},"PeriodicalIF":6.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147414328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2025-11-01DOI: 10.1016/j.echo.2025.09.027
Sara Hungerford MD, PhD
{"title":"Renal Dysfunction, Arterial Stiffness, and the Interpretation of “Global Afterload” in Moderate Aortic Stenosis: What’s Old Is New Again","authors":"Sara Hungerford MD, PhD","doi":"10.1016/j.echo.2025.09.027","DOIUrl":"10.1016/j.echo.2025.09.027","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"39 3","pages":"Pages 326-327"},"PeriodicalIF":6.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145440033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Interatrial communications (IACs) are common in newborns. While most close spontaneously, some persist as patent foramen ovale (PFO) or atrial septal defects (ASDs). While PFOs are mostly benign, ASDs may require surveillance and treatment. Distinguishing ASDs from PFOs in newborns and deciding who requires follow-up can be challenging. We previously developed an algorithm to improve classification of IACs in newborns. This study aimed to evaluate the patency at preschool age of neonatal IACs classified using the algorithm.
Methods
We reexamined children from the Copenhagen Baby Heart Study who underwent neonatal transthoracic echocardiography (TTE). Neonatal TTEs were previously classified into PFO and ASD subtypes using our algorithm. ASDs were distinguished from PFOs by defect size ≥4 mm, abnormal location, or multiple communications. For this study, we reexamined >200 children with each type of neonatal IAC and >200 without a neonatally identified IAC. Patent IACs at follow-up were reclassified using the algorithm.
Results
We reexamined 1,099 children (median age, 5.2 [interquartile range, 4.9-5.5] years; 53% female): 290 with neonatal ASD, 608 with neonatal PFO, and 201 without neonatal IAC. At follow-up, spontaneous closure, that is, no detectable residual shunt by color Doppler, was observed in 81.7% of children with neonatal ASD (n = 237) and in 89.9% of children with neonatal PFO (n = 546). Among children without neonatally identified IACs, the follow-up TTE revealed an IAC in 5.0% (n = 10). Children with a neonatal ASD were 8 times more likely to have an ASD at follow-up than children with a neonatal PFO or no neonatal IAC (adjusted odds ratio, 8.2; 95% CI 3.6-18.7; P < .0001). Four children, all with neonatal ASDs, required surgical ASD closure.
Conclusions
Spontaneous closure rates of all neonatal IAC types were high. Children classified by the algorithm as having neonatal ASD had a significantly higher risk of persistent ASD, supporting its value in identifying newborns who may benefit from follow-up and recommending targeted follow-up of neonatal ASDs only.
{"title":"Follow-Up of Neonatally Diagnosed Atrial Septal Defects and Patent Foramen Ovale at Preschool Age","authors":"Sofie Dannesbo MD, PhD , Anna Maria Dehn MD, PhD , Elisabeth Blixenkrone-Møller MD , Natasja Schytte MD , Giaan Ninh MD , Ruth Ottilia Birgitta Vøgg MD, PhD , Heather A. Boyd PhD , Finn Stener Jørgensen MD, DMSc , Vibeke Hjortdal MD, PhD , Anne-Sophie Sillesen MD, PhD , Anna Axelsson Raja MD, PhD , Niels Vejlstrup MD, PhD , Kasper Iversen MD, DMSc , Henning Bundgaard MD, DMSc","doi":"10.1016/j.echo.2025.11.006","DOIUrl":"10.1016/j.echo.2025.11.006","url":null,"abstract":"<div><h3>Background</h3><div>Interatrial communications (IACs) are common in newborns. While most close spontaneously, some persist as patent foramen ovale (PFO) or atrial septal defects (ASDs). While PFOs are mostly benign, ASDs may require surveillance and treatment. Distinguishing ASDs from PFOs in newborns and deciding who requires follow-up can be challenging. We previously developed an algorithm to improve classification of IACs in newborns. This study aimed to evaluate the patency at preschool age of neonatal IACs classified using the algorithm.</div></div><div><h3>Methods</h3><div>We reexamined children from the Copenhagen Baby Heart Study who underwent neonatal transthoracic echocardiography (TTE). Neonatal TTEs were previously classified into PFO and ASD subtypes using our algorithm. ASDs were distinguished from PFOs by defect size ≥4 mm, abnormal location, or multiple communications. For this study, we reexamined >200 children with each type of neonatal IAC and >200 without a neonatally identified IAC. Patent IACs at follow-up were reclassified using the algorithm.</div></div><div><h3>Results</h3><div>We reexamined 1,099 children (median age, 5.2 [interquartile range, 4.9-5.5] years; 53% female): 290 with neonatal ASD, 608 with neonatal PFO, and 201 without neonatal IAC. At follow-up, spontaneous closure, that is, no detectable residual shunt by color Doppler, was observed in 81.7% of children with neonatal ASD (<em>n</em> = 237) and in 89.9% of children with neonatal PFO (<em>n</em> = 546). Among children without neonatally identified IACs, the follow-up TTE revealed an IAC in 5.0% (<em>n</em> = 10). Children with a neonatal ASD were 8 times more likely to have an ASD at follow-up than children with a neonatal PFO or no neonatal IAC (adjusted odds ratio, 8.2; 95% CI 3.6-18.7; <em>P</em> < .0001). Four children, all with neonatal ASDs, required surgical ASD closure.</div></div><div><h3>Conclusions</h3><div>Spontaneous closure rates of all neonatal IAC types were high. Children classified by the algorithm as having neonatal ASD had a significantly higher risk of persistent ASD, supporting its value in identifying newborns who may benefit from follow-up and recommending targeted follow-up of neonatal ASDs only.</div></div>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"39 3","pages":"Pages 304-315"},"PeriodicalIF":6.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145534203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2026-03-03DOI: 10.1016/j.echo.2026.01.003
{"title":"JASE Reviewers and Guest Editors in 2025","authors":"","doi":"10.1016/j.echo.2026.01.003","DOIUrl":"10.1016/j.echo.2026.01.003","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"39 3","pages":"Pages 241-245"},"PeriodicalIF":6.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147414329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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