Journal of the American Society of Echocardiography最新文献

{"title":"Dapagliflozin and Cardiac Reverse Remodeling: New Insights in the Mechanistic Puzzle of SGLT2 Inhibitors.","authors":"Safia Chatur, Timothy W Churchill","doi":"10.1016/j.echo.2025.01.002","DOIUrl":"10.1016/j.echo.2025.01.002","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142957968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simplifying the Echocardiographic Definition of Atrial Secondary Tricuspid Regurgitation: When Less Is More.","authors":"Rebecca T Hahn","doi":"10.1016/j.echo.2025.01.001","DOIUrl":"https://doi.org/10.1016/j.echo.2025.01.001","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143383841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Continuing Education and Meeting Calendar","authors":"","doi":"10.1016/j.echo.2024.11.003","DOIUrl":"10.1016/j.echo.2024.11.003","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 1","pages":"Page A23"},"PeriodicalIF":5.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143165982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel Echocardiography Feature-Tracking Algorithm for Stabilized Frame-to-Frame Extraction of Aortic Root Diameters in the Parasternal Long Axis","authors":"Frederick W. Damen MD, PhD, Elnaz Ghajar-Rahimi BS, Dongbing Lai PhD, Craig J. Goergen PhD, Benjamin J. Landis MD","doi":"10.1016/j.echo.2024.09.005","DOIUrl":"10.1016/j.echo.2024.09.005","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 1","pages":"Pages 44-47"},"PeriodicalIF":5.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitral Leaflet Separation Revisited: A Surrogate of Mitral Valve Area in Young People With Rheumatic Mitral Regurgitation Living in Remote Areas","authors":"Jacqueline M. Williamson BSc, Bo Remenyi MBBS, PhD, Ari E. Horton MBBS, Peter Morris MBBS, PhD, Gillian A. Whalley PhD","doi":"10.1016/j.echo.2024.10.005","DOIUrl":"10.1016/j.echo.2024.10.005","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 1","pages":"Pages 49-50"},"PeriodicalIF":5.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-Dimensional Transthoracic Echocardiography for Semiautomated Analysis of the Tricuspid Annulus: Validation and Normal Values","authors":"Juan I. Cotella MD ,&nbsp;Alexandra Blitz MS ,&nbsp;Alexandra Clement MD ,&nbsp;Michele Tomaselli MD ,&nbsp;Denisa Muraru MD ,&nbsp;Luigi P. Badano MD ,&nbsp;Natascha Sauber MS ,&nbsp;Adria Font Calvarons MS ,&nbsp;Markus Degel MS ,&nbsp;Agnieszka Rucki PhD ,&nbsp;Michael Blankenhagen MS ,&nbsp;Megan Yamat BS ,&nbsp;Marcus Schreckenberg MS ,&nbsp;Karima Addetia MD ,&nbsp;Federico M. Asch MD ,&nbsp;Victor Mor-Avi PhD ,&nbsp;Roberto M. Lang MD","doi":"10.1016/j.echo.2024.09.007","DOIUrl":"10.1016/j.echo.2024.09.007","url":null,"abstract":"<div><h3>Background</h3><div>The expansion of tricuspid valve (TV) interventions has underscored the need for accurate and reproducible three-dimensional (3D) transthoracic echocardiographic (TTE) tools for evaluating the tricuspid annulus and for 3D normal values of this structure. The aims of this study were to develop new semi-automated software for 3D TTE analysis of the tricuspid annulus, compare its accuracy and reproducibility against those of multiplanar reconstruction (MPR) reference, and determine normative values.</div></div><div><h3>Methods</h3><div>Three-dimensional TTE images of 113 patients with variable degrees of tricuspid regurgitation were analyzed using the new semiautomated software and conventional MPR methodology (as the reference standard), each by three independent readers. For each measured parameter, intertechnique agreement was assessed using linear regression and Bland-Altman analyses, and interreader variability using intraclass correlation coefficients and coefficients of variation. Additionally, 3D TTE data sets of 789 subjects from the WASE (World Alliance Societies of Echocardiography) study were analyzed using this new software to determine normal values for each tricuspid annular (TA) parameter.</div></div><div><h3>Results</h3><div>Semiautomated measurements showed excellent agreement with MPR reference values for all TA measurements: high correlations (all <em>r</em> values &gt;0.8) and minimal biases. All measurements were more reproducible than with MPR: higher intraclass correlation coefficients (0.94-0.96 vs 0.82-0.90) and lower coefficients of variation (5%-12% vs 8%-18%). Sex- and age-related differences were identified in 3D normal values of most TA parameters. Dynamic analysis showed that TA parameters vary throughout the cardiac cycle, reaching minimal values at end-systole and maximum values in late diastole.</div></div><div><h3>Conclusions</h3><div>Novel software for semiautomated analysis of TA geometry and dynamics provides accurate and reproducible measurements. Normal values of TA dimensions, parsed by sex and age, are reported.</div></div>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 1","pages":"Pages 33-43.e3"},"PeriodicalIF":5.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac Function and Functional Capacity in Patients With Long COVID: A Comparison to Propensity-Matched Community Controls","authors":"Thomas H. Marwick MBBS, PhD, MPH ,&nbsp;Noah Wexler MBBS ,&nbsp;Joel Smith MSc ,&nbsp;Leah Wright PhD ,&nbsp;Felicia Ho MBBS ,&nbsp;Marc Oreto BSc ,&nbsp;Ashleigh-Georgia Sherriff BSc ,&nbsp;Richard Allwood BSc ,&nbsp;Yusuke Sata MD, PhD ,&nbsp;Stefano Manca PhD ,&nbsp;Erin Howden PhD ,&nbsp;Quan Huynh PhD","doi":"10.1016/j.echo.2024.09.006","DOIUrl":"10.1016/j.echo.2024.09.006","url":null,"abstract":"<div><h3>Background</h3><div>Cardiac impairment has been associated with acute COVID-19 since the earliest reports of the pandemic. However, its role in postacute sequelae of COVID-19 (“long COVID”) is undefined, and many existing observations about cardiovascular involvement in postacute sequelae of COVID-19 are uncontrolled.</div></div><div><h3>Objective</h3><div>To compare the prevalence of cardiac dysfunction in patients with long COVID and noninfected controls from the same community and explore their association with functional capacity.</div></div><div><h3>Methods</h3><div>Echocardiography was used to assess cardiac structure and function, including the measurement of global longitudinal strain (GLS), in 190 participants with long COVID. All underwent assessment of functional impairment by subjective (Duke Activity Status Index) and objective tests (6-minute walk test). The 190 participants from the long COVID group were matched with those from 979 patients who underwent the same tests in the pre-COVID-19 era, using a propensity score.</div></div><div><h3>Results</h3><div>The 190 patients with long COVID had similar age and risk factor profiles to those of their matched controls. Left ventricular dimensions and geometry, but not diastolic parameters, were significantly altered in the long COVID group. The long COVID group had subclinical systolic dysfunction (GLS 18.5% ± 2.6% vs 19.3% ± 2.7%, <em>P</em> = .005), and more long COVID patients had abnormal (&lt;16%) GLS (13% vs 8%, <em>P</em> = .035). The association of long COVID with abnormal GLS (odds ratio, 1.49 [1.04, 2.45]) was independent of—and had a similar or greater effect size than—age and risk factors. There was no interaction of long COVID with the association of risk factors with GLS. As expected, the long COVID group had significant subjective (&lt;85% predicted METS; 72% vs 5%, <em>P</em> &lt; .001) and objective functional impairment (29% vs 24%, <em>P</em> = .026), but GLS was only weakly associated with both subjective (<em>r</em> = 0.30, <em>P</em> = .005) and objective (<em>r</em> = 0.21, <em>P</em> = .05) functional impairment. The presence of long COVID was independently associated with subjective (odds ratio = 159.7 [95% CI, 61.6-414.2]) and objective functional impairment (odds ratio = 2.8 [95% CI, 1.5-5.2]).</div></div><div><h3>Conclusions</h3><div>Impaired GLS and left ventricular dimensions are the echocardiographic features that are overrepresented in long COVID, and this association is similar to and independent of other risk factors. Impaired GLS is weakly associated with functional impairment.</div></div>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 1","pages":"Pages 16-23.e1"},"PeriodicalIF":5.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reduction of Coronary Flow Velocity Reserve as the Main Driver of Prognostically Beneficial Coronary Revascularization","authors":"Lauro Cortigiani MD ,&nbsp;Nicola Gaibazzi MD ,&nbsp;Quirino Ciampi MD, PhD ,&nbsp;Fausto Rigo MD ,&nbsp;Domenico Tuttolomondo MD ,&nbsp;Francesco Bovenzi MD ,&nbsp;Dario Gregori PhD ,&nbsp;Scipione Carerj MD ,&nbsp;Mauro Pepi MD ,&nbsp;Patricia A. Pellikka MD ,&nbsp;Eugenio Picano MD, PhD ,&nbsp;Stress Echo 2030 study group","doi":"10.1016/j.echo.2024.09.011","DOIUrl":"10.1016/j.echo.2024.09.011","url":null,"abstract":"<div><h3>Background</h3><div>Regional wall motion abnormality (RWMA) can be absent during stress echocardiography (SE) in patients with chronic coronary syndromes (CCS) and angiographically significant coronary artery disease (CAD) despite a reduction of coronary flow velocity reserve (CFVR).</div></div><div><h3>Objectives</h3><div>To assess the value of a physiology-driven approach, based on CFVR, to coronary revascularization in patients with physiologically and anatomically significant disease of the left anterior descending (LAD) coronary artery.</div></div><div><h3>Methods</h3><div>In a 3-center, observational study with retrospective analysis of prospectively acquired data, 749 patients with CCS, CFVR of the LAD ≤2.0, and ≥50% diameter stenosis of the LAD were enrolled. All patients were evaluated with dipyridamole (0.84 mg/kg in 6’) SE. Patients were followed for 6.4 ± 4.5 years for the outcome of all-cause death.</div></div><div><h3>Results</h3><div>Inducible RWMA was present in 295 patients (39%). Coronary flow velocity reserve was lower in patients with inducible RWMA compared to those without (1.51 ± 0.28 vs 1.65 ± 0.25; <em>P</em> &lt; .001). Coronary revascularization was performed in 514 (69%) patients (388 with percutaneous coronary intervention, 126 with coronary artery bypass surgery). Of them, 226 exhibited inducible RWMA and 288 exhibited isolated reduction of CFVR. During the follow-up, 185 (25%) deaths occurred. The 10-year survival in the entire study population was 70%. The survival at 10 years was markedly lower in conservatively treated patients compared to invasively treated patients (53 vs 76%; <em>P</em> &lt; .0001), with no significant difference between those with solitary reduction of CFVR and reduction of CFVR accompanied by concurrent inducible RWMA. Propensity score–weighted all-cause mortality risk was significantly higher for conservative than for invasive strategy (propensity score adjusted hazard ratio = 2.12; 95% CI, 1.51–2.96; <em>P</em> &lt; .0001).</div></div><div><h3>Conclusions</h3><div>In patients with CCS and physiologically and anatomically significant LAD disease, coronary revascularization driven by a reduction in CFVR is accompanied by a prognostic benefit independently of the presence of inducible RWMA.</div></div>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 1","pages":"Pages 24-32"},"PeriodicalIF":5.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142401784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Efficacy of Goal-Directed Valsalva to Elicit Clinically Significant Gradients in Patients With Obstructive Hypertrophic Cardiomyopathy Taking Mavacamten Therapy","authors":"Cody Frye BA, ACS, RDCS,&nbsp;Melissa Escudero MHA, ACS, RDCS, RDMS,&nbsp;William Saunders PhD, MPH,&nbsp;Olafunke Ajijola PharmD, CPP,&nbsp;George Mawardi MD,&nbsp;Shuktika Nandkeolyar MD,&nbsp;Noreen Kelly MD, MBA,&nbsp;Dermot Phelan MD, PhD","doi":"10.1016/j.echo.2024.10.002","DOIUrl":"10.1016/j.echo.2024.10.002","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 1","pages":"Pages 51-52"},"PeriodicalIF":5.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to “Dobutamine in Low-Flow, Low-Gradient Severe Aortic Stenosis With Preserved Ejection Fraction: Is Exercise Testing the Key?”","authors":"Nils Sofus Borg Mogensen MD,&nbsp;Mulham Ali MD,&nbsp;Rasmus Carter-Storch MD, PhD,&nbsp;Mohamed-Salah Annabi MD,&nbsp;Jasmine Grenier-Delaney MD,&nbsp;Jacob Eifer Møller MD, PhD, DMSCi,&nbsp;Kristian Altern Øvrehus MD, PhD,&nbsp;Patricia A. Pellikka MD,&nbsp;Philippe Pibarot DVM, PhD,&nbsp;Marie-Annick Clavel DVM, PhD,&nbsp;Jordi Sanchez Dahl MD, PhD, DMSCi","doi":"10.1016/j.echo.2024.10.013","DOIUrl":"10.1016/j.echo.2024.10.013","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 1","pages":"Pages 55-56"},"PeriodicalIF":5.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142591304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}