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Metabolic effects of using a variable impedance prosthetic knee. 使用可变阻抗假膝的代谢影响。
Q Medicine Pub Date : 2016-01-01 DOI: 10.1682/JRRD.2015.04.0072
Matthew R Williams, Hugh Herr, Susan D'Andrea

A transfemoral amputation has a significant effect on walking. Though current prosthetic knee options serve to restore mobility, as do purely passive devices, they do not fully restore nondisabled gait. Persons with transfemoral amputation incur a higher metabolic cost during walking than persons without amputation and as a result walk slower and for a shorter distance before tiring. An original variable-impedance transmission prosthetic knee (VI Knee) was tested with five study participants with unilateral transfemoral amputation at two steady-state walking speeds, one below and one above their preferred walking speed. While walking with the VI Knee, participants with shorter limbs showed a reduction in metabolic cost compared with their conventional C-Leg prosthesis, while those with longer limbs exhibited an increase. Though differences were observed between speeds, overall, the difference in metabolic cost (reduction or increase) was found to correlate significantly with rise in the center of mass, with those with shorter residual limbs exhibiting less overall lifting of the body during gait.

经股骨截肢对行走有显著影响。虽然目前的假膝可用于恢复活动能力,就像纯被动装置一样,但它们并不能完全恢复非残疾的步态。经股骨截肢的人在步行时比未截肢的人产生更高的代谢成本,因此在疲劳之前走得更慢,距离更短。一种原始的可变阻抗传输假膝(VI knee)在五名单侧经股截肢的研究参与者中测试了两种稳态步行速度,一种低于他们首选的步行速度,一种高于他们首选的步行速度。当使用VI Knee行走时,与传统的C-Leg假肢相比,肢体较短的参与者的代谢成本降低了,而肢体较长的参与者的代谢成本则增加了。虽然观察到速度之间的差异,但总体而言,代谢成本的差异(减少或增加)被发现与质心的上升显著相关,那些残肢较短的人在步态中表现出较少的整体身体提升。
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引用次数: 7
Barriers to outcome measure administration and completion at discharge from inpatient rehabilitation of people with amputation. 结果测量、管理和截肢患者出院后康复完成的障碍。
Q Medicine Pub Date : 2016-01-01 DOI: 10.1682/JRRD.2015.07.0142
Heather M MacKenzie, Danielle B Rice, C Michele Sealy, Peter D Cox, A Barry Deathe, Michael W C Payne

We performed a retrospective chart review of consecutive patients discharged from an inpatient amputee rehabilitation program over a 2 yr period (January 2010-December 2011). Our objective was to determine barriers to the completion of a standardized maximum walk test (MWT) at discharge. Over the study period, there were 190 discharges. The sample had a mean age of 63.5 yr (standard deviation [SD] +/- 14.2 yr), was 71.6% male, and had a majority of transtibial amputation (67%). The average length of inpatient stay was 28.1 d (SD +/- 13.2 d). MWT including distance and time was completed in 149 (78%) of the discharges; the main factors limiting patient performance on this measure were cardiorespiratory fatigue (53%), lower-limb pain (24%), back pain (12%), and skin problems (6%). Among those patients who completed the MWT, in 31% no limiting factor was identified. Forty-one discharge MWTs were not completed as a result of nonambulatory status (34%), acute illness (17%), limb pain (7%), skin problems (12%), or other reasons. Knowing these limitations may direct care from a clinical standpoint and provides valuable data for research planning to further examine outcome measures in this population.

我们对2年期间(2010年1月- 2011年12月)从住院截肢者康复项目中连续出院的患者进行了回顾性图表回顾。我们的目的是确定在出院时完成标准化最大步行测试(MWT)的障碍。在研究期间,有190人出院。样本的平均年龄为63.5岁(标准差[SD] +/- 14.2岁),男性占71.6%,大多数(67%)截肢。平均住院时间28.1 d (SD +/- 13.2 d), 149例(78%)出院患者完成了包括距离和时间在内的MWT;限制患者表现的主要因素是心肺疲劳(53%)、下肢疼痛(24%)、背痛(12%)和皮肤问题(6%)。在完成MWT的患者中,31%没有发现限制因素。由于非运动状态(34%)、急性疾病(17%)、肢体疼痛(7%)、皮肤问题(12%)或其他原因,41例未完成出院MWTs。了解这些局限性可以从临床角度指导护理,并为研究计划提供有价值的数据,以进一步检查该人群的结果措施。
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引用次数: 1
Does comorbid chronic pain affect posttraumatic stress disorder diagnosis and treatment? Outcomes of posttraumatic stress disorder screening in Department of Veterans Affairs primary care. 共病性慢性疼痛是否影响创伤后应激障碍的诊断和治疗?退伍军人事务部初级保健中创伤后应激障碍筛查的结果。
Q Medicine Pub Date : 2016-01-01 DOI: 10.1682/JRRD.2014.10.0237
Samantha D. Outcalt, H. Hoen, Zhangsheng Yu, Tenesha Marie Franks, E. Krebs
Because posttraumatic stress disorder (PTSD) is both prevalent and underrecognized, routine primary care-based screening for PTSD has been implemented across the Veterans Health Administration. PTSD is frequently complicated by the presence of comorbid chronic pain, and patients with both conditions have increased symptom severity and poorer prognosis. Our objective was to determine whether the presence of pain affects diagnosis and treatment of PTSD among Department of Veterans Affairs (VA) patients who have a positive PTSD screening test. This retrospective cohort study used clinical and administrative data from six Midwestern VA medical centers. We identified 4,244 VA primary care patients with a positive PTSD screen and compared outcomes for those with and without a coexisting pain diagnosis. Outcomes were three clinically appropriate responses to positive PTSD screening: (1) mental health visit, (2) PTSD diagnosis, and (3) new selective serotonin reuptake inhibitor (SSRI) prescription. We found that patients with coexisting pain had a lower rate of mental health visits than those without pain (hazard ratio: 0.889, 95% confidence interval: 0.821-0.962). There were no significant differences in the rate of PTSD diagnosis or new SSRI prescription between patients with and without coexisting pain.
由于创伤后应激障碍(PTSD)既普遍又未得到充分认识,因此在退伍军人健康管理局(Veterans Health Administration)实施了常规的基于初级保健的PTSD筛查。创伤后应激障碍常伴有共病性慢性疼痛,两种情况的患者症状严重程度增加,预后较差。我们的目的是确定疼痛的存在是否影响创伤后应激障碍筛查试验阳性的退伍军人事务部(VA)患者的创伤后应激障碍的诊断和治疗。这项回顾性队列研究使用了六个中西部退伍军人医疗中心的临床和管理数据。我们确定了4244名创伤后应激障碍筛查阳性的退伍军人事务部初级保健患者,并比较了有和没有共存疼痛诊断的患者的结果。结果是对阳性PTSD筛查的三个临床适当反应:(1)心理健康就诊,(2)PTSD诊断,(3)新的选择性5 -羟色胺再摄取抑制剂(SSRI)处方。我们发现,共存疼痛患者的心理健康就诊率低于无疼痛患者(风险比:0.889,95%可信区间:0.821-0.962)。在有和没有共存疼痛的患者之间,PTSD诊断率和新的SSRI处方率没有显著差异。
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引用次数: 10
Residual limb skin temperature and thermal comfort in people with amputation during activity in a cold environment. 低温环境下截肢患者残肢皮肤温度与热舒适性研究
Q Medicine Pub Date : 2016-01-01 DOI: 10.1682/JRRD.2015.03.0053
A. Segal, G. Klute
Thermal comfort remains a common problem for people with lower-limb amputation. Both donning a prosthesis and engaging in activity at room temperature can increase residual limb skin temperature; however, the effects of activity on skin temperature and comfort in more extreme environments remain unknown. We examined residual limb skin temperatures and perceived thermal comfort (PTC; 11-point Likert scale) of participants with unilateral transtibial amputation (n = 8) who were snowshoeing in a cold environment. Residual limb skin temperature increased by 3.9°C [3.0°C to 4.7°C] (mean difference [95% confidence interval (CI)], p < 0.001) after two 30 min exercise sessions separated by a 5 min rest session. Minimal cooling (-0.2°C [-1.1°C to 0.6°C]) occurred during the rest period. Similar changes in PTC were found for the residual limb, intact limb, and whole body, with a mean scale increase of 1.6 [1.1 to 2.1] and 1.3 [0.8 to 1.8] for the first and second exercise sessions, respectively (p < 0.001). Activity in a cold environment caused similar increases in residual limb skin temperature as those found in studies conducted at room temperature. Participants with amputation perceived warming as their skin temperature increased during exercise followed by the perception of cooling during rest, despite minimal associated decreases in skin temperature.
对于下肢截肢患者来说,热舒适仍然是一个普遍的问题。佩戴假体和在室温下进行活动都会使残肢皮肤温度升高;然而,在更极端的环境中,活动对皮肤温度和舒适度的影响尚不清楚。我们检测了残肢皮肤温度和感知热舒适(PTC;11分李克特量表)对单侧胫骨截肢(n = 8)在寒冷环境中雪鞋行走的参与者进行了调查。经过两次30分钟的运动和5分钟的休息后,残肢皮肤温度升高3.9°C[3.0°C至4.7°C](平均差值[95%置信区间(CI)], p < 0.001)。在剩余时间内发生最小冷却(-0.2°C[-1.1°C至0.6°C])。残肢、完整肢和全身的PTC变化相似,第一次和第二次运动的平均评分分别增加1.6[1.1 ~ 2.1]和1.3 [0.8 ~ 1.8](p < 0.001)。在寒冷环境下的活动导致残肢皮肤温度的升高,与在室温下进行的研究发现的结果相似。截肢患者在运动时皮肤温度升高,随后在休息时感觉皮肤温度下降,尽管皮肤温度下降很小。
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引用次数: 9
Scoping review of mobility scooter-related research studies. 机动滑板车相关研究的范围综述。
Q Medicine Pub Date : 2016-01-01 DOI: 10.1682/JRRD.2015.05.0084
W. Mortenson, Jenny Kim
Mobility scooters are three- or four-wheeled power mobility devices regularly used by people who have difficulty ambulating. They also differ from power wheelchairs in terms of their driving controls, programmability, seating, and mounting method. Given their growing popularity and anecdotal concerns around their use, a scoping review was undertaken to identify empirical research about mobility scooters and to analyze their study design and purpose. Data sources included MedLINE, Cumulative Index to Nursing and Allied Health Literature, Embase, and PsychINFO. Thirty-two studies met the inclusion criteria. Most studies were descriptive in nature and reported information about scooter users' demographics, scooter-related activities, and accidents. The most common study design was a pre- and postintervention followed by a cross-sectional survey and retrospective review. Despite the increasing use of mobility scooters, surprisingly little scooter-related research has been conducted. Given the nature of most of the research in this area, further empirical evidence is needed to develop a better understanding about the frequency and causes of scooter accidents and the efficacy of interventions to improve users' skills, mobility, and safety.
代步车是行走困难的人经常使用的三轮或四轮动力代步设备。它们在驾驶控制、可编程性、座位和安装方法方面也与电动轮椅不同。考虑到电动滑板车越来越受欢迎,以及人们对其使用的轶事担忧,我们进行了一项范围审查,以确定有关电动滑板车的实证研究,并分析其研究设计和目的。数据来源包括MedLINE、护理和相关健康文献累积索引、Embase和PsychINFO。32项研究符合纳入标准。大多数研究本质上是描述性的,报告了滑板车用户的人口统计信息、滑板车相关活动和事故。最常见的研究设计是在干预前和干预后进行横断面调查和回顾性评价。尽管电动滑板车的使用越来越多,但令人惊讶的是,与滑板车相关的研究却很少。考虑到该领域大多数研究的性质,需要进一步的经验证据来更好地了解滑板车事故的频率和原因,以及提高用户技能、机动性和安全性的干预措施的有效性。
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引用次数: 17
The effects of prosthetic ankle stiffness on stability of gait in people with transtibial amputation. 假体踝关节刚度对胫骨截肢患者步态稳定性的影响。
Q Medicine Pub Date : 2016-01-01 DOI: 10.1682/JRRD.2015.08.0148
Matthew J Major, Martin Twiste, Laurence P J Kenney, David Howard

The ability to control balance during walking is a critical precondition for minimizing fall risk, but this ability is compromised in persons with lower-limb absence because of reduced sensory feedback mechanisms and inability to actively modulate prosthesis mechanical function. Consequently, these individuals are at increased fall risk compared with nondisabled individuals. A number of gait parameters, including symmetry and temporal variability in step/stride characteristics, have been used as estimates of gait stability and fall risk. This study investigated the effect of prosthetic ankle rotational stiffness on gait parameters related to walking stability of transtibial prosthesis users. Five men walked with an experimental prosthesis that allowed for independent modulation of plantar flexion and dorsiflexion stiffness. Two levels of plantar flexion and dorsiflexion stiffness were tested during level, uphill, and downhill walking. The results demonstrate that low plantar flexion stiffness reduced time to foot-flat, and this was associated with increased perceived stability, while low dorsiflexion stiffness demonstrated trends in temporal-spatial parameters that are associated with improved gait stability (reduced variability and asymmetry). Prosthesis design and prescription for low rotational stiffness may enhance gait safety for transtibial prosthesis users at risk of unsteadiness and falls.

行走时控制平衡的能力是减少跌倒风险的关键先决条件,但由于感觉反馈机制减少和无法主动调节假肢机械功能,下肢缺失患者的这种能力受到损害。因此,与非残疾人相比,这些人摔倒的风险更高。许多步态参数,包括对称和步伐/跨步特征的时间变异性,已被用作步态稳定性和跌倒风险的估计。本研究探讨假体踝关节旋转刚度对经胫骨假体使用者行走稳定性相关步态参数的影响。五名男性使用一个实验性假体行走,该假体允许独立调节足底屈曲和背屈刚度。在水平、上坡和下坡行走中测试了两个水平的足底屈曲和背屈刚度。结果表明,低足底屈曲刚度减少了到足平的时间,这与感知稳定性的增加有关,而低背屈刚度表明了与改善步态稳定性(减少变异性和不对称性)相关的时空参数趋势。低旋转刚度的假体设计和处方可以提高有不稳定和跌倒风险的经胫骨假体使用者的步态安全性。
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引用次数: 37
Language treatment prior to anterior temporal lobe surgery: Can naming skills be preserved? 前颞叶手术前的语言治疗:命名能力能保留吗?
Q Medicine Pub Date : 2016-01-01 DOI: 10.1682/JRRD.2014.12.0310
Diane L Kendall, Irene Minkina, Lauren Bislick, Thomas J Grabowski, Vaishali Phatak, JoAnn P Silkes, Jeffrey G Ojemann

Epilepsy affects 1% of the general population and is highly prevalent among Veterans. The purpose of this phase I study was to investigate a presurgical linguistically distributed language treatment program that could potentially diminish effects of proper-name retrieval deficits following left anterior temporal lobe resection for intractable epilepsy. A single-subject multiple-baseline design was employed for three individuals with late-onset chronic left temporal lobe epilepsy. Word retrieval treatment was administered prior to anterior temporal lobe resection. The primary outcome measure was confrontation naming of proper nouns. Immediately posttreatment (before surgery), there was a positive effect for all trained stimuli in the form of improved naming as compared with pretreatment. In addition, trained stimuli were found to be better after surgery than they were at pretreatment baseline, which would not be expected had language treatment not been provided. This series of case studies introduces two fundamentally novel concept: that commonly occurring deficits associated with left temporal lobe epilepsy can be treated despite the presence of damaged neural tissue and that providing this treatment prior to surgery can lead to better preservation of language function after surgery than would be expected if the treatment were not provided.

癫痫影响总人口的1%,在退伍军人中非常普遍。本I期研究的目的是研究一种术前语言分布语言治疗方案,该方案可能会潜在地减少难治性癫痫左前颞叶切除术后专有名称检索缺陷的影响。对3例迟发性慢性左颞叶癫痫患者采用单受试者多基线设计。在前颞叶切除术之前进行单词检索治疗。主要结果测量是专有名词的对抗命名。在治疗后(手术前),与治疗前相比,所有训练过的刺激都以改善命名的形式产生了积极的影响。此外,经过训练的刺激在手术后被发现比在预处理基线时更好,如果没有提供语言治疗,这是不可能的。这一系列的案例研究介绍了两个基本的新概念:尽管存在受损的神经组织,但与左颞叶癫痫相关的常见缺陷是可以治疗的,并且在手术前提供这种治疗可以更好地保留手术后的语言功能,而不是不提供治疗。
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引用次数: 1
Tongue-controlled robotic rehabilitation: A feasibility study in people with stroke. 舌控机器人康复:对中风患者的可行性研究。
Q Medicine Pub Date : 2016-01-01 DOI: 10.1682/JRRD.2015.06.0122
Sarah Ostadabbas, Stephen N Housley, Nordine Sebkhi, Kimberly Richards, David Wu, Zhenxuan Zhang, Maria Garcia Rodriguez, Lindsey Warthen, Crystal Yarbrough, Samir Belagaje, Andrew J Butler, Maysam Ghovanloo

Stroke survivors with severe upper limb (UL) impairment face years of therapy to recover function. Robot-assisted therapy (RT) is increasingly used in the field for goal-oriented rehabilitation as a means to improve function in ULs. To be used effectively for wrist and hand therapy, the current RT systems require the patient to have a minimal active range of movement in the UL, and those that do not have active voluntary movement cannot use these systems. We have overcome this limitation by harnessing tongue motion to allow patients to control a robot using synchronous tongue and hand movement. This novel RT device combines a commercially available UL exoskeleton, the Hand Mentor, and our custom-designed Tongue Drive System as its controller. We conducted a proof-of-concept study on six nondisabled participants to evaluate the system usability and a case series on three participants with movement limitations from poststroke hemiparesis. Data from two stroke survivors indicate that for patients with chronic, moderate UL impairment following stroke, a 15-session training regimen resulted in modest decreases in impairment, with functional improvement and improved quality of life. The improvement met the standard of minimal clinically important difference for activities of daily living, mobility, and strength assessments.

患有严重上肢损伤的中风幸存者需要数年的治疗才能恢复功能。机器人辅助治疗(RT)作为一种改善ULs功能的手段,越来越多地应用于目标导向康复领域。为了有效地用于手腕和手部治疗,目前的RT系统要求患者在UL中具有最小的活动范围,而那些没有主动自主运动的患者不能使用这些系统。我们已经克服了这一限制,利用舌头的运动,让病人通过舌头和手的同步运动来控制机器人。这种新颖的RT设备结合了市售的UL外骨骼,Hand Mentor和我们定制的舌头驱动系统作为控制器。我们对六名非残疾参与者进行了概念验证研究,以评估系统的可用性,并对三名中风后偏瘫患者进行了一系列病例研究。来自两名中风幸存者的数据表明,对于中风后慢性中度UL损伤的患者,15次训练方案导致损伤适度减少,功能改善和生活质量提高。改善符合日常生活活动、活动能力和力量评估的最小临床重要差异标准。
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引用次数: 12
Lessons learned in a clinical trial for military sexual trauma-related posttraumatic stress disorder. 军人性创伤相关创伤后应激障碍临床试验的经验教训。
Q Medicine Pub Date : 2016-01-01 DOI: 10.1682/JRRD.2016.04.0064
Alina Surís, Nicholas Holder, Ryan Holliday, E Ellen Morris, Alina Surís, Nicholas Holder, Ryan Holliday, E Ellen Morris
A large body of literature exists describing the challenges associated with implementing randomized controlled clinical trials (RCTs) [1]. However, when clinical trials are conducted within Department of Veterans Affairs (VA) Medical Center (VAMC) settings, several additional and unique factors contribute to the difficulty of conducting RCTs. The challenges and strategies to address them, described in this editorial, are based on an RCT conducted to determine the effectiveness of an evidence-based therapy to treat Veterans with military sexual trauma (MST)-related posttraumatic stress disorder (PTSD) [2]. Logistical and Environmental Challenges at VAMCs The number of Veterans that VAMCs serve has increased substantially since they were built [3]. Due to the design and age of many VAMCs and the increased demand for care, physical space within many VAMCs is at a premium, often necessitating updates and reorganization that require construction. Some examples of difficulties that were experienced during our study included (1) a large construction project to add needed parking spaces (temporarily reducing existing parking); (2) space issues that required frequent VAMC reorganization and changes in office locations for study therapists and personnel; (3) ongoing construction that produced frequent loud noises; and (4) due to space limitations, female Veterans with MST-related PTSD had to share small waiting rooms with male Veterans prior to study visits, often resulting in distress. Frustration and distress related to these experiences may have affected the way participants completed self-report outcome measures relating to PTSD, anger, depression, and anxiety symptoms. For example, although assessments asked participants to consider a discrete time period encompassing at a minimum the past few days, changes in current affect and anxiety can influence participants' responses [4-5]. Variability in participation could also have been affected by loud construction noise and encounters with male Veterans in small waiting rooms. These events are similar to exposure elements prominent in some therapies for PTSD, and this unintentional form of exposure could interfere with self-report accuracy. Proposed Strategies to Address Logistical and Environmental Challenges We recommend researchers anticipate logistical and environmental challenges by acquiring information about construction schedules; informing participants about construction challenges before starting the study; considering construction-related appointment delays during scheduling; and attempting to create quiet, private waiting areas. To further address space and parking limitations, reducing visits to the medical center can be helpful. For example, we encourage researchers to be flexible with follow-up data collection, such as offering phone assessments. Challenges with Documentation in the VAMC Electronic Medical Record Documentation of the diagnosis and treatment of PTSD in the electronic medical
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引用次数: 8
Effects of high-speed power training on muscle strength and power in patients with multiple sclerosis. 高速力量训练对多发性硬化症患者肌力和力量的影响。
Q Medicine Pub Date : 2016-01-01 DOI: 10.1682/JRRD.2014.08.0186
Carlos Medina-Perez, Fernanda de Souza-Teixeira, Rodrigo Fernandez-Gonzalo, Jose-Aldo Hernandez-Murua, Jose Antonio de Paz-Fernandez

This study examined the effects of a high-speed power training program in peak muscle power and maximal voluntary isometric contraction (MVIC) of knee extensors in patients with relapsing-remitting multiple sclerosis (MS). Forty patients, 20 women (age 42.8 +/- 10.3 yr) and 20 men (age 44.0 +/- 8.7 yr) diagnosed with relapsing-remitting MS were randomly assigned, with respect to sex, to either an exercise group or a control group. Participants from the exercise group performed 12 wk of supervised muscle power training of knee extensors. All subjects were tested for MVIC and peak muscle power at baseline and after the training intervention. A strain gauge was used to measure the MVIC, and peak muscle power was assessed with a linear encoder at five relative loads. The training-related effects were assessed using a t-test. The results showed no significant changes in the control group from baseline to postintervention evaluation. In contrast, the exercise group significantly increased MVIC (10.8%; p < 0.05) and muscle power at 40, 50, 60, 70, and 80% of the MVIC by 21.8, 14.5, 17.3, 19.4, and 22.3%, respectively (p < 0.01), after the training. These findings suggest that 12 wk of high-speed power training improve both MVIC and muscle power at five different loads in patients with relapsing-remitting MS.

本研究考察了高速力量训练计划对复发-缓解型多发性硬化症(MS)患者膝关节伸肌的峰值肌肉力量和最大自主等长收缩(MVIC)的影响。40名患者,20名女性(年龄42.8 +/- 10.3岁)和20名男性(年龄44.0 +/- 8.7岁)被诊断为复发-缓解型多发性硬化症,根据性别随机分配到运动组或对照组。运动组的参与者在监督下进行了12周的膝关节伸肌肌肉力量训练。所有受试者在基线和训练干预后进行MVIC和峰值肌肉力量测试。使用应变计测量MVIC,并使用线性编码器评估五个相对负载下的峰值肌肉功率。训练相关效果采用t检验进行评估。结果显示,对照组从基线到干预后评估无显著变化。相比之下,运动组显著增加MVIC (10.8%;p < 0.05), MVIC为40、50、60、70、80%时的肌力分别提高了21.8、14.5、17.3、19.4、22.3% (p < 0.01)。这些研究结果表明,12周的高速力量训练可以改善复发-缓解型多发性硬化症患者5种不同负荷下的MVIC和肌肉力量。
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引用次数: 23
期刊
Journal of Rehabilitation Research and Development
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