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Clinical Efficacy of Minocycline Hydrochloride for the Treatment of Peri-Implant Disease: A Systematic Review With Meta-Analysis of Randomized Controlled Trials. 盐酸米诺环素治疗种植体周围疾病的临床疗效:随机对照试验荟萃分析的系统评价
IF 1.6 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-06-01 DOI: 10.1563/aaid-joi-D-22-00023
Yanyun Wu, Chunmei Gu, Xin Tong

This systematic review aimed to assess the clinical efficacy of the local application of minocycline hydrochloride for treating peri-implantitis. Four databases-PubMed, EMBASE, Cochrane Library, and China National Knowledge Infrastructure-were searched from their inception through December 2020. English and Chinese randomized controlled trials (RCTs) that compared minocycline hydrochloride with control regimes, including negative control, iodine solution or glycerin, and chlorhexidine, for patients with peri-implant diseases were retrieved. Three outcomes-plaque index (PLI), probing depth (PD), and sulcus bleeding index (SBI)-were assessed using meta-analysis based on the random-effects model. Fifteen RCTs were included in the present meta-analysis, and results suggested that minocycline hydrochloride significantly affected PLI, PD, or SBI reduction regardless of the type of comparator regime. However, subgroup analyses suggested that minocycline hydrochloride was not superior to chlorhexidine in terms of reduction of PLI (1 week: MD = -0.18, 95% CI = -0.55 to 0.20, P = .36; 4 weeks: MD = -0.08, 95% CI = -0.23 to 0.07, P = .28; 8 weeks: MD = -0.01, 95% CI = -0.18 to 0.16, P = .91) and PD (1 week: MD = 0.07, 95% CI = -0.27 to 0.41, P = .68; 4 weeks: MD = -0.10, 95% CI = -0.43 to 0.24, P = .58; 8 weeks: MD = -0.30, 95% CI = -0.68 to 0.08, P = .12), and minocycline hydrochloride was also not better than chlorhexidine regarding reduction of SBI at 1 week after treatment (MD = -0.10; 95% CI = -0.21 to 0.01; P = .08). This study concludes that minocycline hydrochloride as adjuvant therapy of nonsurgical treatment enhances the clinical results when compared to control regimes. However, the difference between minocycline hydrochloride and chlorhexidine should be further investigated by designing additional high-quality studies with large sample sizes.

本系统综述旨在评价局部应用盐酸米诺环素治疗种植体周围炎的临床疗效。四个数据库——pubmed、EMBASE、Cochrane图书馆和中国国家知识基础设施——从其成立到2020年12月进行了检索。检索了中英文随机对照试验(rct),比较盐酸米诺环素与阴性对照、碘溶液或甘油、氯己定治疗种植体周围疾病患者的对照方案。三个结果-斑块指数(PLI),探查深度(PD)和沟出血指数(SBI)-使用基于随机效应模型的荟萃分析进行评估。本荟萃分析纳入了15项随机对照试验,结果表明,无论比较方案的类型如何,盐酸米诺环素显著影响PLI、PD或SBI的降低。然而,亚组分析显示,米诺环素在降低PLI方面并不优于氯己定(1周:MD = -0.18, 95% CI = -0.55 ~ 0.20, P = 0.36;4周:MD = -0.08, 95% CI = -0.23 ~ 0.07, P = 0.28;8周:MD = -0.01, 95% CI = -0.18 ~ 0.16, P = 0.91)和PD(1周:MD = 0.07, 95% CI = -0.27 ~ 0.41, P = 0.68;4周:MD = -0.10, 95% CI = -0.43 ~ 0.24, P = 0.58;8周:MD = -0.30, 95% CI = -0.68 ~ 0.08, P = .12),治疗后1周,米诺环素降低SBI的效果也不优于氯己定(MD = -0.10;95% CI = -0.21 ~ 0.01;P = .08)。本研究得出结论,盐酸二甲胺四环素作为非手术治疗的辅助治疗,与对照组相比,可以提高临床效果。然而,盐酸米诺环素和氯己定之间的差异应该通过设计更多大样本量的高质量研究来进一步研究。
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引用次数: 0
Horizontal Ridge Augmentation Under a Removable Partial Denture and Implant Placement. 在可摘局部义齿和种植体放置下的水平嵴增强。
IF 1.6 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-06-01 DOI: 10.1563/aaid-joi-D-21-00230
Sean W Meitner, Gregori M Kurtzman, Michael Adsit

Implant planning has moved in recent years to virtual planning with a CBCT scan and fabrication of a surgical guide based on that virtual planning. Unfortunately, positioning based on prosthetics is typically missing from the CBCT scan. Use of a diagnostic guide fabricated in office permits information from ideal prosthetic positioning to improve virtual planning and subsequent fabricated of a corrected surgical guide. This becomes more important when insufficiencies in the ridges horizontal aspects (width) will require ridge augmentation to allow later implant placement. This article discusses a case with insufficient ridge width and determination of where augmentation is required to house implants in ideal prosthetic positions, the subsequent grafting, implant placement and restoration.

近年来,植入计划已经转向了虚拟计划,CBCT扫描和基于虚拟计划的手术指南的制作。不幸的是,基于假肢的定位通常在CBCT扫描中缺失。使用在办公室制作的诊断指南,可以从理想的假体定位中获得信息,以改善虚拟规划和随后制作的矫正手术指南。当脊的水平方面(宽度)不足时,这一点就变得更加重要,因为需要增加脊以允许以后植入。本文讨论了一个脊宽不足的病例,并确定了在理想的假体位置需要增加植入物的位置,随后的移植,植入物放置和修复。
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引用次数: 0
Abutment-Bar Structure Connection Geometry: An Important Design Parameter for Implant-Supported Bar-Retained Overdentures With Cantilever Extension. 基台-杆结构连接几何:悬臂式种植支撑杆固位覆盖义齿的重要设计参数。
IF 1.6 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-06-01 DOI: 10.1563/aaid-joi-D-22-00055
Gökçen Akgün, Ramazan Kayacan

When extended distally due to higher loading in the posterior region, implant-supported bar-retained overdentures with cantilever bar extension exhibit greater bending moments on the implants closest to the cantilever bar and increased stresses in the overdenture components. In this study, a new abutment-bar structure connection was introduced to minimize undesired bending moments and reduce the resulting stresses by increasing the rotational mobility of the bar structure on the abutments. Copings of the bar structure were modified to have 2 spherical surfaces, sharing the same center, located at the centroid of the top surface of the coping screw head. The new connection design was applied to a 4 implant-supported mandibular overdenture to create a modified overdenture. Both the classical and modified models had bar structures with cantilever extensions in the first and second molar areas and were analyzed for deformation and stress distribution using finite element analysis, which was also conducted for both the overdenture models without cantilever bar extensions. Real-scale prototypes of both models with cantilever extensions were manufactured, assembled on implants embedded in polyurethane blocks, and subjected to fatigue testing. Both models' implants were subjected to pullout testing. The new connection design increased the rotational mobility of the bar structure, minimized the bending moment effects, and reduced the stress levels in the peri-implant bone and overdenture components, whether cantilevered or not. Our results verify the effects of rotational mobility of the bar structure on the abutments and validate the importance of the abutment-bar connection geometry as a design parameter.

当由于后牙区较高的负荷而向远端伸展时,悬臂杆伸展的种植支撑杆保留覆盖义齿在最靠近悬臂杆的种植体上表现出更大的弯矩,并且覆盖义齿部件的应力增加。在本研究中,引入了一种新的桥台-杆结构连接,通过增加桥台上杆结构的旋转灵活性来最小化不期望的弯矩并减小由此产生的应力。杆结构的顶面被修改为具有两个球面,共享同一中心,位于顶面螺钉头的质心。将新连接设计应用于4根种植体支持的下颌覆盖义齿,形成改良的覆盖义齿。在第一磨牙区和第二磨牙区均采用悬臂杆扩展的经典模型和改进模型,采用有限元方法分析了两种覆盖义齿模型的变形和应力分布,并对无悬臂杆扩展的覆盖义齿模型进行了分析。制造了两种具有悬臂延伸的模型的实际尺寸原型,将其组装在嵌入聚氨酯块的植入物上,并进行疲劳测试。两种模型的植入物都进行了拔出测试。新的连接设计增加了杆结构的旋转灵活性,最大限度地减少了弯矩效应,并降低了种植周骨和覆盖义齿组件的应力水平,无论是否悬臂。我们的研究结果验证了杆结构的旋转移动性对桥台的影响,并验证了桥台-杆连接几何形状作为设计参数的重要性。
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引用次数: 0
Anatomically Driven Immediate Implant Placement in the Esthetic Zone: Two Case Reports as Proof of Principle. 解剖驱动的即刻种植体植入美学区:两个案例报告作为原则的证明。
IF 1.6 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-06-01 DOI: 10.1563/aaid-joi-D-21-00318
Douglas Albert Deporter, Quang Vinh Nguyen, Sichul Charlie Park, Mohammad Mohammad Ketabi

Achieving favorable and stable esthetic outcomes with immediate implants used to replace maxillary anterior teeth can be challenging. Osteotomies need to be initiated along the palatal socket wall, and it is often difficult to stabilize initial drilling. An immediate implant was planned for a hopeless maxillary incisor. Using a flapless surgery technique, the tooth was removed and decoronated, and an entry point was made in the root to guide the osteotomy drills. The root was reinserted and stabilized while a precision drill and 2-mm twist drill were used in sequence to drill through the tooth root, establishing the osteotomy location but stopping 3-4 mm short of final depth. The root was then removed, and the final implant bur for a 3.5 × 11.5-mm implant was drilled to depth, engaging the necessary native bone apically. The original tooth crown was then used to prepare and insert a transitional crown. Reinserting the extracted root of a maxillary anterior tooth and using it as a guide for osteotomy preparation is an excellent method to optimally position an immediate implant palatally in the socket wall.

采用即刻种植体替代上颌前牙,获得良好且稳定的美观效果是具有挑战性的。截骨术需要沿腭窝壁开始,通常难以稳定初始钻孔。对于一个没有希望的上颌门牙,计划立即种植。使用无瓣手术技术,将牙齿移除并装饰,并在牙根处建立入口点以指导截骨钻。重新插入牙根并稳定,同时依次使用精密钻头和2mm麻花钻头钻穿牙根,确定截骨位置,但停止距离最终深度3-4 mm。然后将根拔出,并钻入3.5 × 11.5 mm种植体的最终种植体bur至深度,与必要的原生骨顶端接合。然后使用原牙冠准备并插入过渡牙冠。将拔除的上颌前牙根重新插入,并将其作为截骨准备的指导,是一种将即刻种植体放置在腭槽壁上的最佳方法。
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引用次数: 0
The Use of a Coded Healing Abutment in the Restoration of a Single, Immediately Placed Implant in the Esthetic Zone: A Clinical Case Report. 编码愈合基台在修复单个即刻种植体美学区中的应用:一个临床病例报告。
IF 1.6 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-06-01 DOI: 10.1563/aaid-joi-D-22-00187
Esraa A Attar

For several years, the implant-level impression procedure started by removal of the healing abutment, followed by connection of the impression coping to the implant. Encode Complete (Encode, Biomet 3i, Biomet 3i, Palm Beach Gardens, FL) was introduced to eliminate implant-level impressions by offering a healing abutment-level impression protocol. This report illustrated the treatment of a single tooth in the anterior esthetic zone using Encode Complete. A 23-year-old female patient reported to the prosthodontics clinic complaining of a fractured maxillary anterior tooth that was deemed nonrestorable. After immediate implant placement, soft tissue preservation and temporization of the implant, healing abutment level impression was made. The codes embedded on the occlusal surface communicated the implant depth, hex-orientation, platform diameter, and interface. The definitive Encode gold-plated titanium abutment was anatomically designed virtually with customized margin, contour, taper, and emergence profile. The milling process was initiated, and the virtual design data were sent to the Robocast Center for analog placement in the original Encode master cast. The definitive abutment was placed on the master cast using Robocast technology, followed by the fabrication of the final porcelain fused to zirconia cement-retained all ceramic crown. The abutment was secured to the implant with a Gold-Tite abutment screw, followed by the final cement-retained implant crown placement. Recall visits were obtained at 1 week, 1 month, 3 months, and 1 year after final prosthesis insertion.

几年来,种植体水平的印模手术从移除愈合基台开始,然后将印模顶部连接到种植体上。Encode Complete (Encode, Biomet 3i, Biomet 3i, Palm Beach Gardens, FL)通过提供愈合基台级印模方案来消除种植体级印模。本报告描述了使用Encode Complete治疗单牙前感觉区。一名23岁的女性患者到口腔修复科就诊,主诉上颌前牙骨折,认为无法修复。即刻种植体放置、软组织保存及种植体暂存后,制作愈合基台水平印模。嵌套在咬合面上的编码包含种植体深度、六边形方向、平台直径和界面。最终的Encode镀金钛基台是解剖学上设计的,具有定制的边缘、轮廓、锥度和涌现轮廓。铣削过程开始,虚拟设计数据被发送到Robocast中心,在原始Encode主铸模中进行模拟放置。使用Robocast技术将最终的基台放置在主铸件上,然后制造最终的瓷融合到氧化锆水泥中,保留所有陶瓷冠。用金钛基牙螺钉将基牙固定在种植体上,然后进行最后的骨水泥保留种植体冠置入术。在最终植入假体后1周、1个月、3个月和1年进行回忆访问。
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引用次数: 0
Occlusion and Dental Implants-Where Are We? 咬合和种植牙-我们在哪里?
IF 1.6 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-06-01 DOI: 10.1563/AAID-JOI-D-4903.Editorial
James L Rutkowski, Shankar Iyer
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引用次数: 0
Essential Techniques of Alveolar Bone Augmentation in Implant Dentistry: A Surgical Manual, 2nd edition Edited by: Len Tolstunov, DDS, DMD 种植牙科牙槽骨增强的基本技术:外科手册,第二版编辑:Len Tolstunov, DDS, DMD
4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-06-01 DOI: 10.1563/aaid-joi-d-4903.book.review
Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Essential Techniques of Alveolar Bone Augmentation in Implant Dentistry: A Surgical Manual, 2nd edition Edited by: Len Tolstunov, DDS, DMD. J Oral Implantol 1 June 2023; 49 (3): 340–341. doi: https://doi.org/10.1563/AAID-JOI-D-4903.Book.Review Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest Search
查看图标查看文章内容图表和表格视频音频补充数据同行评审共享图标共享Facebook Twitter LinkedIn电子邮件工具图标工具获得许可引用图标引用搜索网站引文牙槽骨增强的基本技术:外科手册,第二版编辑:Len Tolstunov, DDS, DMD。[J]中华口腔医学杂志(英文版);49(3): 340-341。doi: https://doi.org/10.1563/AAID-JOI-D-4903.Book.Review下载引文文件:Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex工具栏搜索搜索下拉菜单工具栏搜索搜索输入搜索输入自动建议搜索
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引用次数: 0
Horizontal Bone Augmentation With Autogenous and Collagenated Xenogeneic Bone Blocks: A Split-Mouth Prospective Clinical, Tomographic, and Histological Pilot Study. 用自体和胶原异种骨块水平骨增强:一项裂口前瞻性临床、层析成像和组织学初步研究。
IF 1.6 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-06-01 DOI: 10.1563/aaid-joi-D-22-00115
Evellyn Marques, Luiz Antonio Mazzuchelli Cosmo, Marcelo Lucchesi Teixeira, Luís Guilherme Scavone de Macedo, Antonio Carlos Aloise, André Antonio Pelegrine

The aim of this study was to compare the clinical, tomographic, and histological performance of collagenated xenogeneic bone blocks (CXBB) in horizontal bone augmentations for implant placement. Five patients with an absence of the 4 upper incisors and an HAC 3 horizontal bone defect, with a remaining of 3 to 5 mm, underwent a bone-grafting procedure with CXBB (test group [TG], n = 5) and autogenous graft (control group [CG], n = 5), with one type of graft used on the right side and other type on the left side. Changes in bone thickness and density (tomographic evaluation), levels of complications (clinically), and distribution pattern between mineralized and nonmineralized tissue (histomorphometrically) were analyzed. Tomographic analysis showed a horizontal bone increase of 4.25 ± 0.78 mm in the TG and 3.08 ± 0.8 mm in the CG between baseline and 8 months postoperatively (P < .05). The horizontal loss between the day of installation of the blocks and 8 months postoperatively was 1.02 ± 0.39 mm for the TG and 1.10 ± 0.71 mm for the CG (P > .05). With regard to bone density, the TG blocks right after installation had 440.2 ± 89.15 HU, and after 8 months, the region reached 730.7 ± 130.98 HU, representing an increase of 29.05%. For the CG blocks, bone density increased from 1052.2 ± 398.35 HU to 1222.5 ± 453.28 HU, representing an increase of 17.03%. The increase in bone density was significantly higher in the TG (P < .05). Clinically, no cases of exposure of the bone blocks and no failure of incorporation were observed. Histomorphometrically, the percentage of mineralized tissue was lower in the TG than in the CG (48.10% ± 2.88% and 53.53% ± 1.05%, respectively), and the opposite was verified for the levels of nonmineralized tissue (52.79% ± 2.88% and 46.47% ± 1.05%, respectively; P < .05). The use of CXBB achieved higher levels of horizontal gain, with lower bone density and lower levels of mineralized tissue when compared with the use of autogenous blocks.

本研究的目的是比较胶原异种骨块(CXBB)在水平骨增强体植入中的临床、层析成像和组织学表现。5例4个上切牙缺失,HAC - 3水平骨缺损,剩余3 ~ 5mm,采用CXBB(试验组[TG], n = 5)和自体移植物(对照组[CG], n = 5)植骨,一种植骨在右侧,另一种植骨在左侧。分析骨厚度和密度的变化(断层成像评估)、并发症水平(临床)以及矿化和非矿化组织之间的分布模式(组织形态计量学)。ct分析显示,术后8个月TG水平骨增加4.25±0.78 mm, CG水平骨增加3.08±0.8 mm (P < 0.05)。术后8个月TG组和CG组水平损失分别为1.02±0.39 mm和1.10±0.71 mm (P > 0.05)。骨密度方面,刚安装后的TG块为440.2±89.15 HU, 8个月后达到730.7±130.98 HU,增加29.05%。CG组骨密度从1052.2±398.35 HU增加到1222.5±453.28 HU,增加了17.03%。TG组骨密度增加显著高于TG组(P < 0.05)。在临床上,没有观察到骨块暴露和合并失败的病例。在组织形态学上,TG中矿化组织的比例低于CG(分别为48.10%±2.88%和53.53%±1.05%),而非矿化组织的比例则相反(分别为52.79%±2.88%和46.47%±1.05%);P < 0.05)。与使用自体骨块相比,使用CXBB获得了更高水平的水平增益,骨密度更低,矿化组织水平更低。
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引用次数: 0
Flapless Implant Surgery Using an Intraoperative Measuring Guide With Double-Armed Zirconia Sleeves: A Technical Note. 使用双臂氧化锆套管的术中测量指南进行无襟翼种植手术:技术说明。
IF 1.6 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-06-01 DOI: 10.1563/aaid-joi-D-22-00050
Tinglu Fang, Yingkai Wang, Yuxin Lou, Chenyang Xie, Haiyang Yu
This article describes a technique for precise implant placement. Following the preoperative implant planning, the surgical guide including the guide plate, double-armed zirconia sleeves, and indicator components was designed and fabricated. The drill was guided by zirconia sleeves, and the axial direction of the drill was assessed using the indicator components and measuring ruler. The implant was accurately placed in the planned position under the guidance of the guide tube.
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引用次数: 0
Guided Lateral Window Osteotomy Using Dynamic Navigation for Maxillary Sinus Augmentation: A Novel Technique. 动态导航引导侧窗截骨术治疗上颌窦增强:一种新技术。
IF 1.6 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-06-01 DOI: 10.1563/aaid-joi-D-22-00053
Omran Bishbish, Joseph Kan, Yoon Jeong Kim

The size and the position of the sinus antrostomy play a key role in making sinus grafting surgery more predictable and effective with less complications. A cone beam computed tomography and intraoral scan of the maxilla were taken for a patient who is missing maxillary first molar tooth with limited residual bone. Data were exported to the dynamic navigation (DN) system software. Sinus lateral window osteotomy position and dimensions were determined and planned using four 1.5 mm diameter implants placed on the maxillary sinus lateral wall. The osteotomy was initiated following the planned four 1.5 mm implants in a parallel motion to the bone surface using dynamic navigation guidance; thus, creating an outline for the lateral sinus window. Afterword's, the lateral sinus window was greenstick fractured and the membrane was lifted; first molar implant osteotomy done, implant placed, and bone graft material was placed. The flap was sutured, and post-operative instructions and medications were given. No post-operative complications noticed. The outline of the lateral window osteotomy along with implant osteotomy can be accurately planned and executed using DN technology, which may potentially reduce complications and insure accurate placement of the implant and the graft.

窦口造口的大小和位置对鼻窦移植手术的可预测性和有效性以及并发症的减少起着关键作用。本文对上颌第一磨牙缺失,残骨有限的患者进行了锥形束计算机断层扫描和口腔内扫描。数据导出到动态导航(DN)系统软件。在上颌窦外侧壁上放置四个直径1.5 mm的种植体,确定并规划窦侧窗截骨的位置和尺寸。在动态导航引导下,按照计划的4个1.5 mm植入物平行于骨表面运动,开始截骨;这样就形成了外侧窦窗的轮廓。术后,侧窦窗呈绿枝状断裂,膜被提起;第一磨牙种植体截骨,种植体放置,植骨材料放置。缝合皮瓣,给予术后指导和药物治疗。无术后并发症。使用DN技术可以准确地规划和执行侧窗截骨术和种植体截骨术的轮廓,这可能会潜在地减少并发症,并确保种植体和移植物的准确放置。
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引用次数: 0
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Journal of Oral Implantology
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