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A mechano-biological study comparing external fixation using monocortical and bicortical pins in tibial diaphyseal fracture models: A finite element analysis 一项力学生物学研究比较了胫骨骨干骨折模型中使用单皮质和双皮质针的外固定:有限元分析
4区 医学 Q4 BIOPHYSICS Pub Date : 2023-11-03 DOI: 10.1142/s0219519423501014
Targol Bayat, Yousof Mohandes, Mohammad Tahami, Masoud Tahani
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引用次数: 0
Deep Learning-Based Feature Fusion and Transfer Learning for Approximating Pic Value Of COVID-19 Medicine Using Drug Discovery Data 基于深度学习的特征融合和迁移学习,利用药物发现数据逼近COVID-19药物Pic值
4区 医学 Q4 BIOPHYSICS Pub Date : 2023-11-03 DOI: 10.1142/s0219519423501002
Amol Dattatray Dhaygude, Mehadi Hasan, M Vijay, Chittibabu Ravela
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引用次数: 0
Domain-adaptive TSK fuzzy system based on multisource data fusion for epileptic EEG signal classification 基于多源数据融合的域自适应TSK模糊系统在癫痫脑电信号分类中的应用
4区 医学 Q4 BIOPHYSICS Pub Date : 2023-10-21 DOI: 10.1142/s0219519423400900
Zaihe Cheng, Guohua Zhou
In recent years, machine learning methods based on epileptic signals have shown good results with brain-computer interfaces (BCIs). With the continuous expansion of their applications, the demand for labeled epileptic signals is increasing. For a large number of data-driven models, such signals are not suitable, as they extend the calibration cycle. Therefore, a new domain-adaptive TSK fuzzy system model based on multisource data fusion (DA-TSK) is proposed. The purpose of DA-TSK is to maintain high classification performance when the amount of labeled data is insufficient. The DA-TSK model not only has a strong learning ability to learn characteristic information from EEG data but is also interpretable, which aids in the understanding of the analytic process of the model for medical purposes. In particular, this model can make full use of a small amount of labeled EEG data in the source domain and target domain through domain adaptation. Therefore, the DA-TSK model can reduce data dependence to a certain extent and improve the generalization performance of the target classifier. Experiments are performed to evaluate the effectiveness of the DA-TSK model on public EEG datasets based on epileptic signals. The DA-TSK model can obtain satisfactory accuracy when the labeled data are insufficient in the target domain.
近年来,基于癫痫信号的机器学习方法在脑机接口(bci)上取得了良好的效果。随着其应用范围的不断扩大,对标记癫痫信号的需求也在不断增加。对于大量数据驱动的模型,这样的信号是不合适的,因为它们延长了校准周期。为此,提出了一种基于多源数据融合的域自适应模糊系统模型(DA-TSK)。DA-TSK的目的是在标记数据量不足的情况下保持较高的分类性能。DA-TSK模型不仅具有较强的学习能力,可以从脑电图数据中学习特征信息,而且具有可解释性,这有助于医学上理解模型的分析过程。特别地,该模型可以通过域自适应,充分利用源域和目标域的少量标记脑电数据。因此,DA-TSK模型可以在一定程度上降低数据依赖性,提高目标分类器的泛化性能。通过实验验证了基于癫痫信号的DA-TSK模型在公开EEG数据集上的有效性。当目标域的标记数据不足时,DA-TSK模型可以获得满意的精度。
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引用次数: 0
A New Intelligent Model Based on Improved Inception-V3 for Oral Cancer and Cyst Classification 基于改进Inception-V3的口腔癌和囊肿分类智能新模型
4区 医学 Q4 BIOPHYSICS Pub Date : 2023-10-21 DOI: 10.1142/s0219519423400985
Suxian Xiang, Yun He, Chenxi Huang, Ziyi Guo, Siming Lin, Jin Zhu
Oral cancer, which is also called mouth cancer, is cancer of the lining of the mouth, lips, or upper throat that has appeared in more than 355,000 people worldwide and caused more than 177,000 deaths, so it is essential to diagnose it as early as possible. Computed tomography (CT) scan is conducive to oral cancer diagnosis, but classifying oral CT images to cancer and cyst manually is difficult and time-consuming. A novel intelligent model based on improved Inception-v3 for classifying oral cancer and cyst CT images automatically is proposed in this paper. We replace the conventional convolution block in Inception-v3 with the Inverted Bottleneck Block and introduce Squeeze-and-Excitation Block (SEB) and Convolutional Block Attention Block (CBAB). The proposed model in this paper is trained on a dataset consisting of CT images of two classes (oral cancer and cyst), and the proposed model achieves 84.053% accuracy, 82.364% sensitivity, 84.508% specificity for oral cancer classification and outperforms other common models in classifying oral CT images.
口腔癌,又称口腔癌,是一种发生在口腔、嘴唇或喉咙上部的癌症,全世界有超过35.5万人患有口腔癌,造成超过17.7万人死亡,因此尽早诊断是至关重要的。计算机断层扫描(CT)有助于口腔癌的诊断,但人工对口腔CT图像进行肿瘤和囊肿的分类困难且耗时。提出了一种基于改进Inception-v3的口腔癌和囊肿CT图像自动分类智能模型。我们用倒瓶颈块取代了Inception-v3中的传统卷积块,并引入了挤压和激励块(SEB)和卷积块注意块(CBAB)。本文提出的模型在由口腔癌和囊肿两类CT图像组成的数据集上进行训练,该模型对口腔癌的分类准确率为84.053%,灵敏度为82.364%,特异性为84.508%,在口腔CT图像分类方面优于其他常用模型。
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引用次数: 0
Analysis of traditional chinese medicine prescriptions for cerebral stroke-related diseases 脑卒中相关疾病的中药处方分析
4区 医学 Q4 BIOPHYSICS Pub Date : 2023-10-21 DOI: 10.1142/s0219519423400924
Zeguo Shao, Tingting Huang, Yanlin Jiang, Chaoyue Han, Jiankun Chen, WenHao Ju, Li Wang
Cerebral stroke, a type of cerebrovascular disease, has become the second leading cause of death globally. It is closely related to many diseases, including hypertension, diabetes, senile dementia, and so forth. As traditional Chinese medicine formulas are increasingly used to treat stroke and its associated diseases, people have begun to use machine learning methods to analyze Chinese medicine prescriptions and summarize their laws. In this study, we collected the data from classic Chinese formulations. Using the Jaccard similarity coefficient method, we calculated the similarity between different prescriptions. We then employed average linkage clustering, categorizing medicine prescriptions for chronic diseases such as diabetes, hypertension, and coronary heart disease into 12 groups. Some of these included “Heart Failure and Warm Kidney Soup”, “Sinus Chamber Junction Syndrome, Quadruple One Depression, Yi Qi, Activating Blood and Feeding Heart Soup”, “Nerves One, Depression One, Tian Ma Hook and Vine Drink”, and “Bawei Antihypertensive Decoction, Anemia Decoction, Hypotension Decoction, Myocardial Live Drink”. We observed that similar prescriptions had more meaningful mutual references. Subsequently, a correlation algorithm was used to analyze the “indications” and “prescription composition”, revealing 11 effective correlation rules. Among these, palpitations were strongly correlated with Astragalus membranaceus, Angelica sinensis, and cassia twig; weakness with Salvia miltiorrhiza, A. membranaceus, and A. sinensis; headaches with Ligusticum wallichii; and vertigo with A. membranaceus. These findings provided a theoretical reference for using traditional Chinese medicine in treating cerebral stroke and associated illnesses.
脑中风是一种脑血管疾病,已成为全球第二大死亡原因。它与许多疾病密切相关,包括高血压、糖尿病、老年性痴呆等。随着中药方剂越来越多地用于治疗中风及其相关疾病,人们开始使用机器学习方法来分析中药方剂并总结其规律。在本研究中,我们收集了中国经典方剂的数据。采用Jaccard相似系数法计算不同处方间的相似度。然后,我们采用平均连锁聚类,将慢性疾病(如糖尿病、高血压和冠心病)的药物处方分为12组。其中包括“心衰温肾汤”、“窦室结证、四重一郁、益气、活血养心汤”、“神经一、抑郁一、天麻钩藤饮”、“八味降压汤、贫血汤、降压汤、心肌活饮”等。我们观察到相似的处方有更多有意义的相互参考。随后,运用关联算法对“适应症”与“处方成分”进行分析,揭示出11条有效的关联规律。其中,心悸与黄芪、当归、决明子枝相关性强;弱用丹参、黄芪、黄芪;治头痛用川芎;和黄芪引起的眩晕。这些发现为中医药治疗脑卒中及相关疾病提供了理论参考。
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引用次数: 0
A novel deep learning method for brain tumor segmentation in magnetic resonance images based on residual units and modified U-net model 基于残差单元和改进U-net模型的脑肿瘤磁共振图像深度学习分割新方法
4区 医学 Q4 BIOPHYSICS Pub Date : 2023-10-21 DOI: 10.1142/s0219519423400882
Yuxuan Chen, Yunyi Chen, Jian Chen, Chenxi Huang, Bin Wang, Xu Cui
Brain tumors are among the most deadly forms of cancer, as the brain is a crucial organ for human activity. Early detection and treatment are key to recovery. An expert’s final decision on tumor diagnosis mainly depends on the evaluation of Magnetic Resonance Imaging (MRI) images. However, the traditional manual assessment process is time-consuming, error-prone, and relies on the experience and knowledge of doctors, along with other unstable factors. An automated brain tumor detection system can assist radiologists and internal medicine experts in detecting and diagnosing brain tumors. This study proposes a novel deep learning model that combines residual units with a modified U-Net framework for brain tumor segmentation tasks in brain MR images. In this study, the U-Net-based framework is implemented with a stack of neural units and residual units and uses Leaky Rectified Linear Unit (LReLU) as the model’s activation function. First, neural units are added before the first layer of downsampling and upsampling to enhance feature propagation and reuse. Then, the stacking of residual blocks is applied to achieve deep semantic information extraction for downsampling and pixel classification for upsampling. Finally, a single-layer convolution outputs the predicted segmented images. The experimental results show that the segmentation Dice Similarity Coefficient of this model is 90.79%, and the model demonstrates better segmentation accuracy than other research models.
脑瘤是最致命的癌症之一,因为大脑是人类活动的重要器官。早期发现和治疗是康复的关键。专家对肿瘤诊断的最终决定主要取决于对磁共振成像(MRI)图像的评价。然而,传统的人工评估过程耗时长,容易出错,并且依赖于医生的经验和知识,以及其他不稳定因素。一种自动化的脑肿瘤检测系统可以帮助放射科医生和内科专家检测和诊断脑肿瘤。本研究提出了一种新的深度学习模型,该模型将残差单元与改进的U-Net框架相结合,用于脑MR图像中的脑肿瘤分割任务。在本研究中,基于u - net的框架由神经单元和残差单元堆栈实现,并使用Leaky Rectified Linear Unit (LReLU)作为模型的激活函数。首先,在下采样和上采样的第一层之前加入神经单元,增强特征的传播和重用;然后,利用残差块叠加实现下采样的深度语义信息提取和上采样的像素分类。最后,单层卷积输出预测的分割图像。实验结果表明,该模型的分割骰子相似系数为90.79%,分割精度优于其他研究模型。
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引用次数: 0
A deep learning framework-based exercise assessment for rehabilitation of chronic obstructive pulmonary disease 基于深度学习框架的慢性阻塞性肺疾病康复运动评估
4区 医学 Q4 BIOPHYSICS Pub Date : 2023-10-21 DOI: 10.1142/s0219519423400894
Lei Cao, Zhiheng Xie, Tianyu Liu, Zijian Wang, Chunjiang Fan
Chronic obstructive pulmonary disease (COPD), which has a high prevalence and mortality rate, is an irreversible condition marked by airflow restriction with different degrees of reversible damage. Notably, there is no cure for COPD, whose treatment primarily relies on rehabilitation exercises to improve airflow limitation. In this paper, a vision-based rehabilitation exercise efficacy prediction system is proposed to assess the efficacy of rehabilitation training for COPD patients. A camera was utilized to capture rehabilitation training videos of COPD patients, and we also collected various physical indicators. In addition, we used clustering algorithm to divide patients with different rehabilitation effects for subsequent progression analysis. Our model achieved a classification of rehabilitation progress accuracy of 90.6%, making it possible to effectively obtain favorable rehabilitation training results without physician supervision. It was meaningful for helping COPD patients get effective feedback when training alone.
慢性阻塞性肺疾病(Chronic obstructive pulmonary disease, COPD)是一种以气流受限为特征的不可逆疾病,具有不同程度的可逆性损害,发病率和死亡率都很高。值得注意的是,慢性阻塞性肺病无法治愈,其治疗主要依靠康复锻炼来改善气流限制。本文提出了一种基于视觉的康复训练效果预测系统,用于评估COPD患者康复训练的效果。利用摄像机拍摄COPD患者的康复训练视频,并采集各项身体指标。此外,我们使用聚类算法对不同康复效果的患者进行分类,进行后续进展分析。我们的模型实现了90.6%的康复进度分类准确率,可以在没有医生监督的情况下有效获得良好的康复训练效果。这对于帮助COPD患者在单独训练时获得有效的反馈有意义。
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引用次数: 0
ERRATUM — RESEARCH ON 3D RECONSTRUCTION METHOD AND APPLICATION OF FOOD IN STROKE PATIENTS BASED ON RGB-D IMAGE 勘误 - 基于RGB-D图像的脑卒中患者食物三维重建方法及应用研究
IF 0.8 4区 医学 Q4 BIOPHYSICS Pub Date : 2023-10-19 DOI: 10.1142/s0219519423920021
Chendi Yuan, Jian-Kun Chen, Fei Wang, Jing-Jie Ouyang, Tao Jing, Xue-Fei Wang, Bo Yang, Zeguo Shao
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引用次数: 0
CORRIGENDUM — FRACTOGRAPHIC ANALYSIS OF LITHIUM DISILICATE CERAMICS AND MONOLITHIC ZIRCONIA CERAMICS 勘误-二硅酸锂陶瓷和单片氧化锆陶瓷的断口分析
4区 医学 Q4 BIOPHYSICS Pub Date : 2023-10-19 DOI: 10.1142/s021951942392001x
SHANYU ZHOU, YUEHUA YOU
Journal of Mechanics in Medicine and BiologyOnline Ready No AccessCORRIGENDUM — FRACTOGRAPHIC ANALYSIS OF LITHIUM DISILICATE CERAMICS AND MONOLITHIC ZIRCONIA CERAMICSis erratum ofFRACTOGRAPHIC ANALYSIS OF LITHIUM DISILICATE CERAMICS AND MONOLITHIC ZIRCONIA CERAMICSSHANYU ZHOU and YUEHUA YOUSHANYU ZHOUDepartment of Stomatology, Affiliated Longhua People’s Hospital, Southern Medical University, Shenzhen, Guangdong 518109, P. R. China and YUEHUA YOUDepartment of Stomatology, Affiliated Longhua People’s Hospital, Southern Medical University, Shenzhen, Guangdong 518109, P. R. Chinahttps://doi.org/10.1142/S021951942392001XCited by:0 (Source: Crossref) Next AboutSectionsView articleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsRecommend to Library ShareShare onFacebookTwitterLinked InRedditEmail View articleJournal of Mechanics in Medicine and Biology Vol. 22, No. 3 (2022) 2240012 (13 pages) https://doi.org/10.1142/S0219519422400127 FiguresReferencesRelatedDetailsRelated articlesFRACTOGRAPHIC ANALYSIS OF LITHIUM DISILICATE CERAMICS AND MONOLITHIC ZIRCONIA CERAMICS29 Mar 2022Journal of Mechanics in Medicine and Biology Recommended Online Ready Metrics History Published: 19 October 2023 PDF download
医学和生物力学杂志在线准备无检索更正-二硅酸锂陶瓷和单片氧化锆陶瓷的断口学分析——对二硅酸锂陶瓷和单片氧化锆陶瓷断口学分析的校错周善宇和尤岳华周善宇南方医科大学附属龙华人民医院口腔科,广东深圳518109南方医科大学附属龙华人民医院口腔科,广东深圳518109中国人民共和国https://doi.org/10.1142/S021951942392001XCited by:0(来源:交叉参考)下一个关于章节查看文章查看全文pdf /EPUB工具添加到收藏夹下载CitationsTrack引文推荐到图书馆分享分享在facebook上推特链接在redditemail查看文章医学和生物学力学杂志Vol. 22,No. 3(2022) 2240012(13页)https://doi.org/10.1142/S0219519422400127图参考文献相关细节相关文章二硅酸锂陶瓷和单片氧化锆陶瓷的断口分析2022年3月29日医学和生物学力学杂志推荐在线准备测量历史出版:2023年10月19日PDF下载
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引用次数: 0
A sentiment analysis model for electroencephalogram signals of students in universities using a convolutional neural network and support vector machine models 基于卷积神经网络和支持向量机模型的大学生脑电图信号情感分析模型
4区 医学 Q4 BIOPHYSICS Pub Date : 2023-10-13 DOI: 10.1142/s0219519423400869
Xuezhi Fan, Jie Zhang, Mengting Yang
Sentiment analysis in teaching evaluation has significant implications. By analyzing students’ sentiments toward instructors, educational institutions can gain valuable insights into teaching effectiveness. These data can guide curriculum development, instructional improvements, and faculty training initiatives. Positive sentiment indicates effective teaching methods, engagement, and student satisfaction; negative sentiment flags areas that need attention. Sentiment analysis can help identify patterns, trends, and outliers, aiding in targeted interventions and personalized support. It also enables comparisons across different courses, instructors, and departments. However, it is crucial to ensure the accuracy and fairness of sentiment analysis algorithms, considering potential biases and the contextual nature of the feedback. This study proposes a sentiment classification model CNN–SVM that combines a convolutional neural network (CNN) and a support vector machine (SVM). Taking students majoring in art in comprehensive colleges and universities as the research object, by collecting the electroencephalogram (EEG) signals of students during teaching evaluation. CNN–SVM is used as the emotional analysis model to obtain the emotional analysis of teaching evaluation results. EEG is a typical physiological signal, and data based on this signal can more truly reflect student emotions. The adaptive CNN feature extraction function and the super generalization classification performance of SVM can reduce the individual differences and data noise between data, thereby improving sentiment classification performance. The experimental results demonstrate that using technology to analyze sentiment can assist educational institutions in more properly comprehending the feedback and opinions of students on instruction. With regard to sentiment analysis, the CNN–SVM method that is derived to produce the fusion algorithm has solid performance.
情感分析在教学评价中具有重要意义。通过分析学生对教师的情感,教育机构可以对教学效果获得有价值的见解。这些数据可以指导课程开发、教学改进和教师培训计划。积极的情绪表明有效的教学方法、参与度和学生满意度;负面情绪标志着需要关注的领域。情感分析可以帮助识别模式、趋势和异常值,帮助有针对性的干预和个性化的支持。它还可以在不同的课程、教师和部门之间进行比较。然而,考虑到潜在的偏见和反馈的上下文性质,确保情感分析算法的准确性和公平性至关重要。本文提出了一种结合卷积神经网络(CNN)和支持向量机(SVM)的情感分类模型CNN - SVM。以综合类院校艺术专业学生为研究对象,通过采集学生在教学评价过程中的脑电图信号。采用CNN-SVM作为情感分析模型,对教学评价结果进行情感分析。脑电图是一种典型的生理信号,基于脑电图的数据更能真实地反映学生的情绪。自适应CNN特征提取函数和支持向量机的超泛化分类性能可以减少数据之间的个体差异和数据噪声,从而提高情感分类性能。实验结果表明,利用情感分析技术可以帮助教育机构更好地理解学生对教学的反馈和意见。在情感分析方面,推导出的CNN-SVM方法产生的融合算法具有较好的性能。
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