Pub Date : 2023-12-06DOI: 10.1097/inf.0000000000004168
Teresita Sarquis, Carolina Ibáñez, Verónica De La Maza, Romina Valenzuela, Marcela Zubieta, Yenis Labraña, Valentina Gutiérrez, Claudia Greppi, Daniela Martínez, Paulina Díaz, María Elena Santolaya
The collection of blood cultures (BC) is key for guiding antimicrobial therapy in children with febrile neutropenia (FN), more than 90% have central venous catheters (CVC). There is no consensus on the need for peripheral BC over central BC in this population. The aim of this study was to determine the contribution of peripheral BC over central BC in the diagnosis of bloodstream infections in children with FN.
收集血液培养物（BC）是指导发热性中性粒细胞减少症（FN）患儿抗菌治疗的关键，90% 以上的患儿使用中心静脉导管（CVC）。关于该人群是否需要外周 BC 而非中心 BC，目前尚未达成共识。本研究旨在确定在诊断发热性中性粒细胞减少症患儿的血流感染时，外周BC比中心BC的作用更大。
{"title":"Usefulness of Peripheral Blood Cultures in Children With Cancer and Episodes of Fever and Neutropenia.","authors":"Teresita Sarquis, Carolina Ibáñez, Verónica De La Maza, Romina Valenzuela, Marcela Zubieta, Yenis Labraña, Valentina Gutiérrez, Claudia Greppi, Daniela Martínez, Paulina Díaz, María Elena Santolaya","doi":"10.1097/inf.0000000000004168","DOIUrl":"https://doi.org/10.1097/inf.0000000000004168","url":null,"abstract":"The collection of blood cultures (BC) is key for guiding antimicrobial therapy in children with febrile neutropenia (FN), more than 90% have central venous catheters (CVC). There is no consensus on the need for peripheral BC over central BC in this population. The aim of this study was to determine the contribution of peripheral BC over central BC in the diagnosis of bloodstream infections in children with FN.","PeriodicalId":501652,"journal":{"name":"The Pediatric Infectious Disease Journal","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138564198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-13DOI: 10.1097/inf.0000000000004134
Alexis Rybak, Naïm Ouldali, Emmanuelle Varon, Muhamed-Kheir Taha, Stéphane Bonacorsi, Stéphane Béchet, François Angoulvant, Robert Cohen, Corinne Levy
In France, vaccination has been implemented against Hi serotype b (Hib), pneumococcus with pneumococcal conjugate vaccines (PCV), and Neisseria meningitidis serogroup C (MenC). These interventions with different coverage and uptake have disrupted the epidemiology of vaccine-preventable acute bacterial meningitis (ABM).
在法国，疫苗接种主要针对乙型流感嗜血杆菌 (Hib)、肺炎球菌结合疫苗 (PCV) 和脑膜炎奈瑟菌 C 血清群 (MenC)。这些覆盖率和接种率不同的干预措施扰乱了疫苗可预防的急性细菌性脑膜炎 (ABM) 的流行病学。
{"title":"Vaccine-preventable Pediatric Acute Bacterial Meningitis in France: A Time Series Analysis of a 19-Year Prospective National Surveillance Network.","authors":"Alexis Rybak, Naïm Ouldali, Emmanuelle Varon, Muhamed-Kheir Taha, Stéphane Bonacorsi, Stéphane Béchet, François Angoulvant, Robert Cohen, Corinne Levy","doi":"10.1097/inf.0000000000004134","DOIUrl":"https://doi.org/10.1097/inf.0000000000004134","url":null,"abstract":"In France, vaccination has been implemented against Hi serotype b (Hib), pneumococcus with pneumococcal conjugate vaccines (PCV), and Neisseria meningitidis serogroup C (MenC). These interventions with different coverage and uptake have disrupted the epidemiology of vaccine-preventable acute bacterial meningitis (ABM).","PeriodicalId":501652,"journal":{"name":"The Pediatric Infectious Disease Journal","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138745850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-11DOI: 10.1097/inf.0000000000004173
Joukje E Willemsen, José A M Borghans, Louis J Bont, Julia Drylewicz
The European Medicines Agency and the US Food and Drug Administration have recently approved a maternal vaccine for respiratory syncytial virus. The US Food and Drug Administration limits vaccination to later in pregnancy. Mathematical modeling demonstrates that this vaccination window may reduce the global mortality impact of the vaccine by 12%. Policymakers should carefully consider vaccine risks and benefits to safeguard vulnerable infants effectively.
{"title":"Disagreement FDA and EMA on RSV Maternal Vaccination: Possible Consequence for Global Mortality.","authors":"Joukje E Willemsen, José A M Borghans, Louis J Bont, Julia Drylewicz","doi":"10.1097/inf.0000000000004173","DOIUrl":"https://doi.org/10.1097/inf.0000000000004173","url":null,"abstract":"The European Medicines Agency and the US Food and Drug Administration have recently approved a maternal vaccine for respiratory syncytial virus. The US Food and Drug Administration limits vaccination to later in pregnancy. Mathematical modeling demonstrates that this vaccination window may reduce the global mortality impact of the vaccine by 12%. Policymakers should carefully consider vaccine risks and benefits to safeguard vulnerable infants effectively.","PeriodicalId":501652,"journal":{"name":"The Pediatric Infectious Disease Journal","volume":"151 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138688352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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