{"title":"Fibrous Bands: An Alternate Diagnosis to Consider for Range of Motion Limitations in Suspected Juvenile Idiopathic Arthritis.","authors":"Aaisham Ali,Debra Liane Bartley,Roberta Audrey Berard","doi":"10.3899/jrheum.2025-0898","DOIUrl":"https://doi.org/10.3899/jrheum.2025-0898","url":null,"abstract":"","PeriodicalId":501812,"journal":{"name":"The Journal of Rheumatology","volume":"173 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145525156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-15DOI: 10.3899/jrheum.2025-0651
Huda Alfaris,Rita Katznelson,Sindhu R Johnson
{"title":"Refractory Systemic Sclerosis-Related Digital Ulcer Successfully Treated With Hyperbaric Oxygen Therapy: A Case Report and Literature Review.","authors":"Huda Alfaris,Rita Katznelson,Sindhu R Johnson","doi":"10.3899/jrheum.2025-0651","DOIUrl":"https://doi.org/10.3899/jrheum.2025-0651","url":null,"abstract":"","PeriodicalId":501812,"journal":{"name":"The Journal of Rheumatology","volume":"95 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145525154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The MAGIC (Mouth and Genital Ulcers With Inflamed Cartilage) of VEXAS: A Case of Overlap Between Behçet Disease and VEXAS Syndrome.","authors":"Elia Touma,Shay Brikman,Nadeem Shorbaji,Amir Bieber","doi":"10.3899/jrheum.2025-0924","DOIUrl":"https://doi.org/10.3899/jrheum.2025-0924","url":null,"abstract":"","PeriodicalId":501812,"journal":{"name":"The Journal of Rheumatology","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145525159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-15DOI: 10.3899/jrheum.2025-0696
Karmela K Chan,Nilasha Ghosh,Carlos Aude,Edward DiCarlo,Anne R Bass
{"title":"Arthroplasty Joint Histology and Surgical Outcomes in Patients on Immune Checkpoint Inhibitors: A Single-Center Case Series.","authors":"Karmela K Chan,Nilasha Ghosh,Carlos Aude,Edward DiCarlo,Anne R Bass","doi":"10.3899/jrheum.2025-0696","DOIUrl":"https://doi.org/10.3899/jrheum.2025-0696","url":null,"abstract":"","PeriodicalId":501812,"journal":{"name":"The Journal of Rheumatology","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145525152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-15DOI: 10.3899/jrheum.2025-0776
Dana Y L Lee,Sharmayne R E Brady,Tai-Juan Aw
{"title":"An Uncommon Case of Cerebellar Leukoencephalopathy Secondary to Low-Dose Methotrexate.","authors":"Dana Y L Lee,Sharmayne R E Brady,Tai-Juan Aw","doi":"10.3899/jrheum.2025-0776","DOIUrl":"https://doi.org/10.3899/jrheum.2025-0776","url":null,"abstract":"","PeriodicalId":501812,"journal":{"name":"The Journal of Rheumatology","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145525155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-15DOI: 10.3899/jrheum.2025-0465
Heta Patel,Sarah Stoots,Joan Von Feldt,Joshua F Baker
OBJECTIVEWe aimed to evaluate the performance of cardiovascular risk prediction tools in identifying Systemic Lupus Erythematosus (SLE) patients with coronary artery calcification (CAC).METHODSWe conducted a post-hoc analysis of a prior case-control study of adult, female patients with SLE and matched controls. We excluded patients who already met cardiology guidelines for recommended statin use. We risk stratified patients per Atherosclerotic Cardiovascular Disease (ASCVD) and SLE-specific risk (SLECRISK) criteria and determined rates of abnormal CAC. We used two-sample t-tests, two-sample Wilcoxon rank-sum (Mann-Whitney) tests, and Chi-squared tests to compare various characteristics between subgroups and used logistic regression to assess adjusted risk for SLE patients compared to controls.RESULTSWe analyzed 128 patients with SLE and 138 controls. Rates of abnormal CAC between the SLE and control groups were 31.3% (40/128) and 12.3% (17/138) with similar mean ASCVD risk scores (2.2% vs. 1.9%). Both the ASCVD and SLECRISK scores had relatively high specificity (95-100%) for abnormal CAC. The ASCVD score demonstrated poor sensitivity in both control (17.6%) and SLE (15.0%) groups with sensitivity doubling to 30.8% among SLE patients with the use of the SLECRISK score. Among lupus participants who were low ASCVD risk, those with abnormal CAC were more likely to be older and have lower GFR, longer disease duration, higher insulin resistance, and higher LDL and cholesterol levels.CONCLUSIONThe poor performance of conventional and even modified risk scores suggest a continued need for screening approaches, including CAC, to determine cardiovascular disease risk in the lupus patient population.
{"title":"Performance of Risk Score Calculators in the Identification of Coronary Artery Calcification in Patients with Systemic Lupus Erythematosus.","authors":"Heta Patel,Sarah Stoots,Joan Von Feldt,Joshua F Baker","doi":"10.3899/jrheum.2025-0465","DOIUrl":"https://doi.org/10.3899/jrheum.2025-0465","url":null,"abstract":"OBJECTIVEWe aimed to evaluate the performance of cardiovascular risk prediction tools in identifying Systemic Lupus Erythematosus (SLE) patients with coronary artery calcification (CAC).METHODSWe conducted a post-hoc analysis of a prior case-control study of adult, female patients with SLE and matched controls. We excluded patients who already met cardiology guidelines for recommended statin use. We risk stratified patients per Atherosclerotic Cardiovascular Disease (ASCVD) and SLE-specific risk (SLECRISK) criteria and determined rates of abnormal CAC. We used two-sample t-tests, two-sample Wilcoxon rank-sum (Mann-Whitney) tests, and Chi-squared tests to compare various characteristics between subgroups and used logistic regression to assess adjusted risk for SLE patients compared to controls.RESULTSWe analyzed 128 patients with SLE and 138 controls. Rates of abnormal CAC between the SLE and control groups were 31.3% (40/128) and 12.3% (17/138) with similar mean ASCVD risk scores (2.2% vs. 1.9%). Both the ASCVD and SLECRISK scores had relatively high specificity (95-100%) for abnormal CAC. The ASCVD score demonstrated poor sensitivity in both control (17.6%) and SLE (15.0%) groups with sensitivity doubling to 30.8% among SLE patients with the use of the SLECRISK score. Among lupus participants who were low ASCVD risk, those with abnormal CAC were more likely to be older and have lower GFR, longer disease duration, higher insulin resistance, and higher LDL and cholesterol levels.CONCLUSIONThe poor performance of conventional and even modified risk scores suggest a continued need for screening approaches, including CAC, to determine cardiovascular disease risk in the lupus patient population.","PeriodicalId":501812,"journal":{"name":"The Journal of Rheumatology","volume":"149 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145525157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-15DOI: 10.3899/jrheum.2025-0684
Wen Qi,Sai Yan Yuen,Mihaela Luminita Popescu,Roger Yang,Charles-Edouard Giguère
OBJECTIVEThe objective of this scoping review was to summarize the current literature on the burden of inflammatory arthritis, tenosynovitis, and enthesitis detected on musculoskeletal ultrasound (MSUS) in adult systemic lupus erythematosus (SLE) patients.METHODSSystematic literature search was performed using Pubmed, Embase and Cochrane Library between January 1st 2015 and February 1st 2025, according to the PRISMA extension for scoping reviews. To be included, studies on the adult SLE population must have reported on either synovitis, tenosynovitis or enthesitis. Exclusion criteria were pediatric studies, rhupus-only studies, case series with less than 5 patients, review articles and conference abstracts. A pre-established standardized data collection sheet was used.RESULTSThe literature search found 24 articles that met inclusion criteria. Studies reported on inflammatory arthritis (n= 20), tenosynovitis (n = 16), and enthesitis (n = 7). Most studies were cross sectional (n = 20/24). Using criteria that were discriminatory for inflammatory enthesitis (power doppler and bone erosion), inflammatory enthesitis was found in SLE patients, and they were more common at the distal patellar, proximal patellar and quadriceps enthesis. In the general SLE population, studies on inflammatory arthritis and tenosynovitis found clinical arthritis in 18-38% of patients, MSUS arthritis in 33-55% of patients, subclinical MSUS arthritis in 9-21% of patients and tenosynovitis in 8-38% of patients. MSUS findings correlated with SLE disease activity indices, such as SLEDAI and BILAG.CONCLUSIONEnthesitis may be a new musculoskeletal domain in SLE. MSUS can be useful in diagnosing tenosynovitis and subclinical inflammatory arthritis in SLE patients.
{"title":"The Burden of Enthesitis, Inflammatory Arthritis and Tenosynovitis on Musculoskeletal Ultrasound in Systemic Lupus Erythematous: A Scoping Review.","authors":"Wen Qi,Sai Yan Yuen,Mihaela Luminita Popescu,Roger Yang,Charles-Edouard Giguère","doi":"10.3899/jrheum.2025-0684","DOIUrl":"https://doi.org/10.3899/jrheum.2025-0684","url":null,"abstract":"OBJECTIVEThe objective of this scoping review was to summarize the current literature on the burden of inflammatory arthritis, tenosynovitis, and enthesitis detected on musculoskeletal ultrasound (MSUS) in adult systemic lupus erythematosus (SLE) patients.METHODSSystematic literature search was performed using Pubmed, Embase and Cochrane Library between January 1st 2015 and February 1st 2025, according to the PRISMA extension for scoping reviews. To be included, studies on the adult SLE population must have reported on either synovitis, tenosynovitis or enthesitis. Exclusion criteria were pediatric studies, rhupus-only studies, case series with less than 5 patients, review articles and conference abstracts. A pre-established standardized data collection sheet was used.RESULTSThe literature search found 24 articles that met inclusion criteria. Studies reported on inflammatory arthritis (n= 20), tenosynovitis (n = 16), and enthesitis (n = 7). Most studies were cross sectional (n = 20/24). Using criteria that were discriminatory for inflammatory enthesitis (power doppler and bone erosion), inflammatory enthesitis was found in SLE patients, and they were more common at the distal patellar, proximal patellar and quadriceps enthesis. In the general SLE population, studies on inflammatory arthritis and tenosynovitis found clinical arthritis in 18-38% of patients, MSUS arthritis in 33-55% of patients, subclinical MSUS arthritis in 9-21% of patients and tenosynovitis in 8-38% of patients. MSUS findings correlated with SLE disease activity indices, such as SLEDAI and BILAG.CONCLUSIONEnthesitis may be a new musculoskeletal domain in SLE. MSUS can be useful in diagnosing tenosynovitis and subclinical inflammatory arthritis in SLE patients.","PeriodicalId":501812,"journal":{"name":"The Journal of Rheumatology","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145525176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01DOI: 10.3899/jrheum.2025-1016
Avira Som,Naomi J Patel
{"title":"Ongoing Benefits of SARS-CoV-2 Vaccination and Booster Vaccination 5 Years Following the Start of the COVID-19 Pandemic.","authors":"Avira Som,Naomi J Patel","doi":"10.3899/jrheum.2025-1016","DOIUrl":"https://doi.org/10.3899/jrheum.2025-1016","url":null,"abstract":"","PeriodicalId":501812,"journal":{"name":"The Journal of Rheumatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145424146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01DOI: 10.3899/jrheum.2025-1004
Simon J Bowman,Benjamin A Fisher
{"title":"Sjögren Disease: Does an Accurate Diagnosis Matter?","authors":"Simon J Bowman,Benjamin A Fisher","doi":"10.3899/jrheum.2025-1004","DOIUrl":"https://doi.org/10.3899/jrheum.2025-1004","url":null,"abstract":"","PeriodicalId":501812,"journal":{"name":"The Journal of Rheumatology","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145424143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01DOI: 10.3899/jrheum.2025-0903
Daiki Nakagomi,Shunichiro Hanai
{"title":"Bone Erosion Repair With a Janus Kinase Inhibitor.","authors":"Daiki Nakagomi,Shunichiro Hanai","doi":"10.3899/jrheum.2025-0903","DOIUrl":"https://doi.org/10.3899/jrheum.2025-0903","url":null,"abstract":"","PeriodicalId":501812,"journal":{"name":"The Journal of Rheumatology","volume":"128 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145424148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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