Pub Date : 2025-11-21DOI: 10.47102/annals-acadmedsg.2025286
Ting Wei Teo, Tiong Cheng Yeo
{"title":"Different faces of atrial septal aneurysm.","authors":"Ting Wei Teo, Tiong Cheng Yeo","doi":"10.47102/annals-acadmedsg.2025286","DOIUrl":"https://doi.org/10.47102/annals-acadmedsg.2025286","url":null,"abstract":"","PeriodicalId":502093,"journal":{"name":"Annals of the Academy of Medicine, Singapore","volume":"54 12","pages":"786-788"},"PeriodicalIF":2.0,"publicationDate":"2025-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145914492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Oesophago-gastro-duodenoscopy (OGD) is the gold standard for evaluating upper gastrointestinal (UGI) symptoms. However, the quality of endoscopic examinations varies widely. This paper, initiated by the Gastroenterological Society of Singapore (GESS), aims to standardise best practices and enhance OGD procedure quality in Singapore.
Method: A core group of 6 experienced gastroenterologists conducted a comprehensive literature review, referencing established international guidelines. They developed preliminary statements, which underwent 2 rounds of formal voting by a broader group of consultant-level gastroenterologists. Statements were reviewed, modified and re-evaluated using the Delphi process, and assigned levels of evidence and recommendation using the US Preventive Services Task Force model. The threshold for acceptance of statements was agreed to be 80% or higher.
Results: Twenty consensus statements were finalised, covering pre-requisite, pre-procedure, intra-procedure and post-procedure quality indicators.
Conclusion: The GESS consensus statements provide recommendations for institutions in Singapore to establish quality standards for white light UGI endoscopy, facilitating high-quality, safe and accurate endoscopic care.
{"title":"Establishing quality standards for white light upper gastrointestinal endoscopy in Singapore: Consensus statements from the Gastroenterological Society of Singapore.","authors":"Heng Boon Yim, Wei Lu, Christopher Tze Wei Chia, Kenneth Koo, Wee Khoon Ng, Tju Siang Chua","doi":"10.47102/annals-acadmedsg.2025204","DOIUrl":"https://doi.org/10.47102/annals-acadmedsg.2025204","url":null,"abstract":"<p><strong>Introduction: </strong>Oesophago-gastro-duodenoscopy (OGD) is the gold standard for evaluating upper gastrointestinal (UGI) symptoms. However, the quality of endoscopic examinations varies widely. This paper, initiated by the Gastroenterological Society of Singapore (GESS), aims to standardise best practices and enhance OGD procedure quality in Singapore.</p><p><strong>Method: </strong>A core group of 6 experienced gastroenterologists conducted a comprehensive literature review, referencing established international guidelines. They developed preliminary statements, which underwent 2 rounds of formal voting by a broader group of consultant-level gastroenterologists. Statements were reviewed, modified and re-evaluated using the Delphi process, and assigned levels of evidence and recommendation using the US Preventive Services Task Force model. The threshold for acceptance of statements was agreed to be 80% or higher.</p><p><strong>Results: </strong>Twenty consensus statements were finalised, covering pre-requisite, pre-procedure, intra-procedure and post-procedure quality indicators.</p><p><strong>Conclusion: </strong>The GESS consensus statements provide recommendations for institutions in Singapore to establish quality standards for white light UGI endoscopy, facilitating high-quality, safe and accurate endoscopic care.</p>","PeriodicalId":502093,"journal":{"name":"Annals of the Academy of Medicine, Singapore","volume":"54 12","pages":"766-778"},"PeriodicalIF":2.0,"publicationDate":"2025-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145914480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-13DOI: 10.47102/annals-acadmedsg.2025340
Benjamin Kian Chung Ong
{"title":"The importance of multi-level resilience in healthcare systems in small countries like Singapore.","authors":"Benjamin Kian Chung Ong","doi":"10.47102/annals-acadmedsg.2025340","DOIUrl":"https://doi.org/10.47102/annals-acadmedsg.2025340","url":null,"abstract":"","PeriodicalId":502093,"journal":{"name":"Annals of the Academy of Medicine, Singapore","volume":"54 11","pages":"736-738"},"PeriodicalIF":2.0,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145795847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-11DOI: 10.47102/annals-acadmedsg.2025330
Stefan H Oehlers, Dorothy Hui Lin Ng
{"title":"Mycobacterium abscessus treatment: From empiricism to mechanism.","authors":"Stefan H Oehlers, Dorothy Hui Lin Ng","doi":"10.47102/annals-acadmedsg.2025330","DOIUrl":"https://doi.org/10.47102/annals-acadmedsg.2025330","url":null,"abstract":"","PeriodicalId":502093,"journal":{"name":"Annals of the Academy of Medicine, Singapore","volume":"54 11","pages":"684-685"},"PeriodicalIF":2.0,"publicationDate":"2025-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145795849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-10DOI: 10.47102/annals-acadmedsg.2025102
Jia Jia Lee, Yiyun Shou, Lay Hoon Goh, Cynthia Chen, Andrew Teik Hong Chen, Ngan Phoon Fong, Jose M Valderas, Nan Luo
{"title":"Healthier SG awareness and enrolment among persons with chronic disease.","authors":"Jia Jia Lee, Yiyun Shou, Lay Hoon Goh, Cynthia Chen, Andrew Teik Hong Chen, Ngan Phoon Fong, Jose M Valderas, Nan Luo","doi":"10.47102/annals-acadmedsg.2025102","DOIUrl":"https://doi.org/10.47102/annals-acadmedsg.2025102","url":null,"abstract":"","PeriodicalId":502093,"journal":{"name":"Annals of the Academy of Medicine, Singapore","volume":"54 12","pages":"800-805"},"PeriodicalIF":2.0,"publicationDate":"2025-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145914473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-07DOI: 10.47102/annals-acadmedsg.2025116
Ruthra Mohan, Evelyn Lai Ming Ho, Pek-Lan Khong
{"title":"MRI landscape in Southeast Asia.","authors":"Ruthra Mohan, Evelyn Lai Ming Ho, Pek-Lan Khong","doi":"10.47102/annals-acadmedsg.2025116","DOIUrl":"https://doi.org/10.47102/annals-acadmedsg.2025116","url":null,"abstract":"","PeriodicalId":502093,"journal":{"name":"Annals of the Academy of Medicine, Singapore","volume":"54 12","pages":"806-808"},"PeriodicalIF":2.0,"publicationDate":"2025-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145914516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-06DOI: 10.47102/annals-acadmedsg.2025209
Lok Pui Ng, Qi He Mabel Leow, Aminath Shiwaza Moosa, Keng Fang Tan, Yi Xuan Valerie Chan, Shin Yu Sim, Ngiap Chuan Tan, Ding Xuan Ng
{"title":"Physical activity patterns and associated factors among youths in Singapore: A cross-sectional islandwide community study.","authors":"Lok Pui Ng, Qi He Mabel Leow, Aminath Shiwaza Moosa, Keng Fang Tan, Yi Xuan Valerie Chan, Shin Yu Sim, Ngiap Chuan Tan, Ding Xuan Ng","doi":"10.47102/annals-acadmedsg.2025209","DOIUrl":"10.47102/annals-acadmedsg.2025209","url":null,"abstract":"","PeriodicalId":502093,"journal":{"name":"Annals of the Academy of Medicine, Singapore","volume":" ","pages":"45-48"},"PeriodicalIF":2.0,"publicationDate":"2025-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146069448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-04DOI: 10.47102/annals-acadmedsg.2025227
Albert Yick Hou Lim, Kevin Pethe, Cheryl Hui Ling Khoong, Peter Dedon, Gerhard Grüber
Introduction: Mycobacterium abscessus complex (MABC) is an emerging global threat due to its intrinsic and acquired resistance to many antibiotics, making treatment particularly challenging. This systematic review aimed to evaluate current treatment regimens and clinical outcomes in patients with MABC pulmonary disease.
Method: A comprehensive electronic search of PubMed, Embase and Cochrane databases was conducted for studies published between 1 January 2010 and 31 December 2024. A total of 28 studies met the inclusion criteria, comprising 24 retrospective chart reviews and 4 multicentre prospective studies.
Results: Sputum culture conversion (SCC) was reported in 25 studies, with rates ranging from 29% to 77%. Radiographic improvement was observed in 33% to 54% of patients, while clinical improvement varied widely, ranging from 14% to 91%. Notably, infections caused by M. massiliense were consistently associated with superior clinical, radiologic, and microbiologic outcomes compared to M. abscessus. Although surgical intervention was reported in selected cases, it was associated with higher SCC rates and remains a definitive treatment option in refractory disease. The overall risk of bias across studies was moderate to high, largely due to the predominance of retrospective study designs and heterogeneity in treatment protocols and outcome measures.
Conclusion: These findings underscore the suboptimal outcomes associated with current treatment strategies for MABC pulmonary disease. There is an urgent need for large-scale, multicentre prospective studies utilising standardised treatment outcome definitions and unified therapeutic regimens to improve patient care and clinical outcomes.
{"title":"Treatment outcomes in Mycobacterium abscessus pulmonary disease: A systematic review.","authors":"Albert Yick Hou Lim, Kevin Pethe, Cheryl Hui Ling Khoong, Peter Dedon, Gerhard Grüber","doi":"10.47102/annals-acadmedsg.2025227","DOIUrl":"10.47102/annals-acadmedsg.2025227","url":null,"abstract":"<p><strong>Introduction: </strong>Mycobacterium abscessus complex (MABC) is an emerging global threat due to its intrinsic and acquired resistance to many antibiotics, making treatment particularly challenging. This systematic review aimed to evaluate current treatment regimens and clinical outcomes in patients with MABC pulmonary disease.</p><p><strong>Method: </strong>A comprehensive electronic search of PubMed, Embase and Cochrane databases was conducted for studies published between 1 January 2010 and 31 December 2024. A total of 28 studies met the inclusion criteria, comprising 24 retrospective chart reviews and 4 multicentre prospective studies.</p><p><strong>Results: </strong>Sputum culture conversion (SCC) was reported in 25 studies, with rates ranging from 29% to 77%. Radiographic improvement was observed in 33% to 54% of patients, while clinical improvement varied widely, ranging from 14% to 91%. Notably, infections caused by M. massiliense were consistently associated with superior clinical, radiologic, and microbiologic outcomes compared to M. abscessus. Although surgical intervention was reported in selected cases, it was associated with higher SCC rates and remains a definitive treatment option in refractory disease. The overall risk of bias across studies was moderate to high, largely due to the predominance of retrospective study designs and heterogeneity in treatment protocols and outcome measures.</p><p><strong>Conclusion: </strong>These findings underscore the suboptimal outcomes associated with current treatment strategies for MABC pulmonary disease. There is an urgent need for large-scale, multicentre prospective studies utilising standardised treatment outcome definitions and unified therapeutic regimens to improve patient care and clinical outcomes.</p>","PeriodicalId":502093,"journal":{"name":"Annals of the Academy of Medicine, Singapore","volume":"54 11","pages":"699-720"},"PeriodicalIF":2.0,"publicationDate":"2025-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145795794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The impact of oppressive behaviours on female general surgical trainees' educational experience in Malaysia.","authors":"April Camilla Roslani, Retnagowri Rajandram, Anthonia Ginika Uzoigwe, Wah Yun Low","doi":"10.47102/annals-acadmedsg.202510","DOIUrl":"https://doi.org/10.47102/annals-acadmedsg.202510","url":null,"abstract":"","PeriodicalId":502093,"journal":{"name":"Annals of the Academy of Medicine, Singapore","volume":"54 11","pages":"739-741"},"PeriodicalIF":2.0,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145795777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-30DOI: 10.47102/annals-acadmedsg.2025195
Samantha Hui Ling Cheong, Jia Hong Koh, Christopher Cheang Han Leo, Emmett Tsz Yeung Wong, Wei-Zhen Hong, Priyanka Khatri
{"title":"Patient-identified barriers to elective dialysis initiation in Singapore: A cross-sectional study.","authors":"Samantha Hui Ling Cheong, Jia Hong Koh, Christopher Cheang Han Leo, Emmett Tsz Yeung Wong, Wei-Zhen Hong, Priyanka Khatri","doi":"10.47102/annals-acadmedsg.2025195","DOIUrl":"https://doi.org/10.47102/annals-acadmedsg.2025195","url":null,"abstract":"","PeriodicalId":502093,"journal":{"name":"Annals of the Academy of Medicine, Singapore","volume":"54 12","pages":"792-795"},"PeriodicalIF":2.0,"publicationDate":"2025-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145914510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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