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Competence and Assessment: Meeting the Needs of Accuracy and Fairness 能力与评估:满足准确性和公平性的需要
Pub Date : 2024-05-13 DOI: 10.1097/as9.0000000000000410
Sarah Jung, Ting Sun
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引用次数: 0
Use and Outcomes of Dexamethasone in the Management of Malignant Small Bowel Obstruction 地塞米松在恶性小肠梗阻治疗中的应用和效果
Pub Date : 2024-05-06 DOI: 10.1097/as9.0000000000000431
Frank F. Yang, Elina Serrano, Kyle S. Bilodeau, Michael Weykamp, Caitlin J. Silvestri, Ashleigh C. M. Bull, Brenda Lin, Sara L. Schaefer, Colette Galet, Luis J. Garcia, Baraka Gitonga, D. T. Kolodziej, Samantha Esposito, Molly Parker-Brigham, Rohan Luhar, Avinash Mamgain, Kendrick C. Brown, S. Dewdney, T. Price, N. Siparsky, Sarah Knerr, Pauline K. Park, Sabrina Sanchez, D. Skeete, K. Fischkoff, D. Flum
To describe rates of dexamethasone use in the nonoperative management of malignant small bowel obstruction (mSBO) and their outcomes. mSBO is common in patients with advanced abdominal-pelvic cancers. Management includes prioritizing quality of life and avoiding surgical intervention when possible. The use of dexamethasone to restore bowel function is recommended in the National Comprehensive Cancer Network guidelines for mSBO. Yet, it is unknown how often dexamethasone is used for mSBO and whether results from nonresearch settings support its use. This is a multicenter retrospective cohort study including unique admissions for mSBO from January 1, 2019 to December 31, 2021. Dexamethasone use and management outcomes were summarized with descriptive statistics and multiple logistic regression. Among 571 admissions (68% female, mean age 63 years, 85% history of abdominal surgery) that were eligible and initially nonoperative, 26% [95% confidence interval (CI) = 23%–30%] received dexamethasone treatment (69% female, mean age 62 years, 87% history of abdominal surgery). Dexamethasone use by site ranged from 13% to 52%. Among dexamethasone recipients, 13% (95% CI = 9%–20%) subsequently required nonelective surgery during the same admission and 4 dexamethasone-related safety-events were reported. Amongst 421 eligible admissions where dexamethasone was not used, 17% (95% CI = 14%–21%) required nonelective surgery. Overall, the unadjusted odds ratio (OR) for nonelective surgery with dexamethasone use compared to without its use was 0.7 (95% CI = 0.4–1.3). Using multiple logistic regression, OR after adjusting for site, age, sex, history of abdominal surgery, nasogastric tube, and Gastrografin use was 0.6 (95% CI = 0.3–1.1). Dexamethasone was used in about 1 in 4 eligible mSBO admissions with high variability of use between tertiary academic centers. This multicenter retrospective cohort study suggested an association between dexamethasone use and lower rates of nonelective surgery, representing a potential opportunity for quality improvement.
目的:描述地塞米松在恶性小肠梗阻(mSBO)非手术治疗中的使用率及其结果。处理方法包括优先考虑生活质量,尽可能避免手术干预。美国国家综合癌症网络(National Comprehensive Cancer Network)的 mSBO 指南推荐使用地塞米松来恢复肠道功能。然而,目前尚不清楚地塞米松在 mSBO 中的使用频率,以及非研究机构的结果是否支持使用地塞米松。 这是一项多中心回顾性队列研究,包括2019年1月1日至2021年12月31日期间因mSBO入院的独特病例。通过描述性统计和多元逻辑回归总结了地塞米松的使用情况和管理结果。 在符合条件且最初未进行手术的 571 例入院患者(68% 为女性,平均年龄 63 岁,85% 有腹部手术史)中,26% [95% 置信区间 (CI) = 23%-30%] 接受了地塞米松治疗(69% 为女性,平均年龄 62 岁,87% 有腹部手术史)。地塞米松在不同部位的使用率从 13% 到 52% 不等。在接受地塞米松治疗的患者中,有13%(95% CI = 9%-20%)随后需要在同一次入院过程中进行非选择性手术,并报告了4起与地塞米松相关的安全事件。在421例未使用地塞米松的合格入院患者中,17%(95% CI = 14%-21%)需要进行非选择性手术。总体而言,使用地塞米松与未使用地塞米松相比,非选择性手术的未调整几率比(OR)为 0.7(95% CI = 0.4-1.3)。通过多元逻辑回归,在调整了手术部位、年龄、性别、腹部手术史、鼻胃管和 Gastrografin 的使用后,OR 为 0.6(95% CI = 0.3-1.1)。 大约每 4 例符合条件的 mSBO 住院患者中就有 1 例使用地塞米松,而各三级学术中心使用地塞米松的情况差异很大。这项多中心回顾性队列研究表明,地塞米松的使用与非选择性手术率较低之间存在关联,这为提高质量提供了潜在的机会。
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引用次数: 0
Patient and Hospital Characteristics Associated with Admission Among Patients With Minor Isolated Extremity Firearm Injuries: A Propensity-Matched Analysis 与轻微孤立性肢端枪伤患者入院相关的患者和医院特征:倾向匹配分析
Pub Date : 2024-05-06 DOI: 10.1097/as9.0000000000000430
Arielle C. Thomas, R. Royan, A. Nathens, Brendan T. Campbell, Susheel Reddy, Sarabeth Spitzer, D. Hamad, Angie Jang, Anne M. Stey
To quantify the association between insurance and hospital admission following minor isolated extremity firearm injury. The association between insurance and injury admission has not been examined. This was an observational retrospective cohort study of minor isolated extremity firearm injury captured in the Healthcare Cost and Utilization Project State Inpatient and Emergency Department Databases in 6 states (New York, Arkansas, Wisconsin, Massachusetts, Florida, and Maryland) from 2016 to 2017 among patients aged 16 years or older. The primary exposure was insurance. Admitted patients were propensity score matched to nonadmitted patients on age, extremity Abbreviated Injury Score, and Elixhauser Comorbidity Index with exact matching within hospital to adjust for selection bias. A general estimating equation logistic regression estimated the association between insurance and odds of admission in the matched cohort while controlling for sex, race, injury intent, injury type, hospital profit type, and trauma center designation with observations clustered by propensity score-matched pairs within hospital. A total of 8151 patients presented to hospital with a minor isolated extremity firearm injury between 2016 and 2017 in 6 states. Patients were 88.0% male, 56.6% Black, and 71.7% aged 16 to 36 years old, and 22.1% were admitted. A total of 2090 patients were matched on propensity for admission. Privately insured matched patients had 1.70 higher adjusted odds of admission and 95% confidence interval of 1.30 to 2.22, compared with uninsured after adjusting for patient and hospital characteristics. Insurance was associated with hospital admission for minor isolated extremity firearm injury.
量化轻微孤立肢体枪伤后保险与入院之间的关联。 保险与受伤入院之间的关系尚未得到研究。 这是一项观察性回顾性队列研究,研究对象为 2016 年至 2017 年期间 6 个州(纽约州、阿肯色州、威斯康星州、马萨诸塞州、佛罗里达州和马里兰州)的轻微孤立肢体枪伤患者,数据采集于医疗成本与利用项目州住院患者和急诊科数据库。主要接触因素是保险。入院患者与非入院患者在年龄、肢体简略损伤评分和Elixhauser综合指数上进行倾向评分匹配,并在医院内进行精确匹配,以调整选择偏差。一般估计方程逻辑回归估计了匹配队列中保险与入院几率之间的关系,同时控制了性别、种族、受伤意图、受伤类型、医院利润类型和创伤中心指定,观察结果按医院内倾向得分匹配对分组。 2016年至2017年期间,6个州共有8151名轻微孤立肢体火器伤患者到医院就诊。患者中88.0%为男性,56.6%为黑人,71.7%年龄在16至36岁之间,22.1%为住院患者。共有 2090 名患者与入院倾向相匹配。在对患者和医院特征进行调整后,与未投保的患者相比,投保私人保险的匹配患者的调整后入院几率高出 1.70,95% 置信区间为 1.30 至 2.22。 保险与轻微孤立肢体火器伤入院相关。
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引用次数: 0
The Union Army’s Surgical Handbook and the Positive Story of Civil War Surgery 联邦军的外科手册和内战外科的正面故事
Pub Date : 2024-05-02 DOI: 10.1097/as9.0000000000000419
John M. Harris
Western armies have relied on surgical field manuals to help physicians deal with unfamiliar combat medical conditions from the Napoleonic wars to the present day, but there has been little discussion of whether these handbooks have been used or improved outcomes. Recent research shows that the Union Army’s American Civil War (1861–1865) surgical case fatality rates improved as the war progressed, much like the US Army’s experience in later wars, and were generally superior to comparable European results. These positive Civil War outcomes have been attributed to field experience, adoption of best practices, and enhanced communication, without consideration of New York surgeon Stephen Smith’s widely-used Hand-Book of Surgical Operations. The Army of the Potomac added Smith’s pocket-sized Hand-Book to its supply table in 1862. Northern medical journals applauded it, and Smith’s contemporaries documented its wide use. Smith’s handbook explained and demonstrated surgical techniques that were adopted as the war progressed, such as the use of general anesthesia and limb-sparing resection (debridement) of gunshot wounds. It offered pithy, well-documented advice from recognized experts along with numerous illustrations, which allowed untrained physicians to visualize anatomical relationships and see contemporary best practices in a way that no other wartime publication provided, making it an exemplar of a mass-media surgical improvement change agent.
从拿破仑战争至今,西方军队一直依赖外科野战手册来帮助医生处理陌生的作战医疗状况,但很少有人讨论这些手册是否得到了应用或改善了结果。最近的研究表明,随着战争的进行,美国内战(1861-1865 年)中联邦军的外科病例死亡率有所提高,这与美国军队在后来战争中的经验非常相似,而且总体上优于欧洲的同类结果。内战中的这些积极成果被归功于实战经验、最佳实践的采用以及交流的加强,但没有考虑到纽约外科医生斯蒂芬-史密斯(Stephen Smith)广泛使用的《外科手术手册》。1862 年,波托马克军团将史密斯的袖珍手册添加到供应桌上。北方的医学杂志对这本手册大加赞赏,史密斯的同时代人也记录了这本手册的广泛使用。史密斯的手册解释并演示了随着战争的进行而被采用的外科技术,如使用全身麻醉和枪伤的保肢切除术(清创术)。该手册提供了来自知名专家的精辟、有据可查的建议,并配有大量插图,使未经训练的医生能够直观地了解解剖关系,并以其他战时出版物无法提供的方式看到当代最佳实践,使其成为大众传媒外科改进变革的典范。
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引用次数: 0
Systematic Review of Surgical Care in the Incarcerated Population: Identifying Knowledge Gaps for Future Research 被监禁人群外科护理的系统性回顾:确定未来研究的知识空白
Pub Date : 2024-05-02 DOI: 10.1097/as9.0000000000000434
Totadri Dhimal, Paula Cupertino, Aqsa Ghaffar, Yue Li, Xueya Cai, Cristopher Soto, Megha Ramaswamy, Bruce W. Herdman, Fergal J. Fleming, A. Loria
This study, examining literature up to December 2023, aims to comprehensively assess surgical care for incarcerated individuals, identifying crucial knowledge gaps for informing future health services research and interventions. The US prison system detains around 2 million individuals, mainly young, indigent males from ethnic and racial minorities. The constitutional right to healthcare does not protect this population from unique health challenges and disparities. The scarcity of literature on surgical care necessitates a systematic review to stimulate research, improve care quality, and address health issues within this marginalized community. A systematic review, pre-registered with the International Prospective Register of Systematic Reviews (CRD42023454782), involved searches in PubMed, Embase, and Web of Science. Original research on surgical care for incarcerated individuals was included, excluding case reports/series (<10 patients), abstracts, and studies involving prisoners of war, plastic surgeries for recidivism reduction, transplants using organs from incarcerated individuals, and nonconsensual surgical sterilization. Out of 8209 studies screened, 118 met inclusion criteria, with 17 studies from 16 distinct cohorts reporting on surgical care. Predominantly focusing on orthopedic surgeries, supplemented by studies in emergency general, burns, ophthalmology, and kidney transplantation, the review identified delayed hospital presentations, a high incidence of complex cases, and low postoperative follow-up rates. Notable complications, such as nonfusion and postarthroplasty infections, were more prevalent in incarcerated individuals compared with nonincarcerated individuals. Trauma-related mortality rates were similar, despite lower intraabdominal injuries following penetrating abdominal injuries in incarcerated patients. While some evidence suggests inferior surgical care in incarcerated patients, the limited quality of available studies underscores the urgency of addressing knowledge gaps through future research. This is crucial for patients, clinicians, and policymakers aiming to enhance care quality for a population at risk of surgical complications during incarceration and postrelease.
本研究对截至 2023 年 12 月的文献进行了审查,旨在全面评估针对被监禁人员的外科护理,找出关键的知识差距,为未来的医疗服务研究和干预措施提供参考。 美国监狱系统关押着约 200 万人,主要是来自少数民族和少数种族的年轻贫困男性。宪法规定的医疗保健权并不能保护这些人免受独特的健康挑战和差异的影响。由于有关外科护理的文献很少,因此有必要进行一次系统性回顾,以促进研究、提高护理质量并解决这一边缘化群体的健康问题。 该系统性综述已在《国际系统性综述前瞻性注册》(CRD42023454782)中进行了预先注册,并在 PubMed、Embase 和 Web of Science 中进行了检索。纳入了有关被监禁者外科护理的原创研究,但不包括病例报告/系列研究(小于 10 名患者)、摘要以及涉及战俘、为减少再犯而进行的整形手术、使用被监禁者器官进行的移植以及未经同意的绝育手术的研究。 在筛选出的 8209 项研究中,有 118 项符合纳入标准,其中 17 项研究来自 16 个不同的队列,报告了外科护理情况。研究主要集中在骨科手术方面,并辅以普通急诊、烧伤、眼科和肾移植方面的研究,研究发现了住院时间延迟、复杂病例发生率高以及术后随访率低的问题。与非监禁人员相比,监禁人员更容易出现明显的并发症,如非融合性感染和关节成形术后感染。尽管监禁患者腹部穿透伤后腹腔内损伤较少,但与创伤相关的死亡率相似。 虽然有些证据表明监禁患者的外科护理效果较差,但现有研究的质量有限,这凸显了通过未来研究填补知识空白的紧迫性。这对患者、临床医生和政策制定者来说至关重要,他们的目标是提高对监禁期间和释放后有手术并发症风险的人群的护理质量。
{"title":"Systematic Review of Surgical Care in the Incarcerated Population: Identifying Knowledge Gaps for Future Research","authors":"Totadri Dhimal, Paula Cupertino, Aqsa Ghaffar, Yue Li, Xueya Cai, Cristopher Soto, Megha Ramaswamy, Bruce W. Herdman, Fergal J. Fleming, A. Loria","doi":"10.1097/as9.0000000000000434","DOIUrl":"https://doi.org/10.1097/as9.0000000000000434","url":null,"abstract":"\u0000 \u0000 This study, examining literature up to December 2023, aims to comprehensively assess surgical care for incarcerated individuals, identifying crucial knowledge gaps for informing future health services research and interventions.\u0000 \u0000 \u0000 \u0000 The US prison system detains around 2 million individuals, mainly young, indigent males from ethnic and racial minorities. The constitutional right to healthcare does not protect this population from unique health challenges and disparities. The scarcity of literature on surgical care necessitates a systematic review to stimulate research, improve care quality, and address health issues within this marginalized community.\u0000 \u0000 \u0000 \u0000 A systematic review, pre-registered with the International Prospective Register of Systematic Reviews (CRD42023454782), involved searches in PubMed, Embase, and Web of Science. Original research on surgical care for incarcerated individuals was included, excluding case reports/series (<10 patients), abstracts, and studies involving prisoners of war, plastic surgeries for recidivism reduction, transplants using organs from incarcerated individuals, and nonconsensual surgical sterilization.\u0000 \u0000 \u0000 \u0000 Out of 8209 studies screened, 118 met inclusion criteria, with 17 studies from 16 distinct cohorts reporting on surgical care. Predominantly focusing on orthopedic surgeries, supplemented by studies in emergency general, burns, ophthalmology, and kidney transplantation, the review identified delayed hospital presentations, a high incidence of complex cases, and low postoperative follow-up rates. Notable complications, such as nonfusion and postarthroplasty infections, were more prevalent in incarcerated individuals compared with nonincarcerated individuals. Trauma-related mortality rates were similar, despite lower intraabdominal injuries following penetrating abdominal injuries in incarcerated patients.\u0000 \u0000 \u0000 \u0000 While some evidence suggests inferior surgical care in incarcerated patients, the limited quality of available studies underscores the urgency of addressing knowledge gaps through future research. This is crucial for patients, clinicians, and policymakers aiming to enhance care quality for a population at risk of surgical complications during incarceration and postrelease.\u0000","PeriodicalId":503165,"journal":{"name":"Annals of Surgery Open","volume":"75 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141018013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Sociodemographic Factors With Overtriage, Undertriage, and Value of Care After Major Surgery 社会人口因素与大手术后护理过度、护理不足和护理价值的关系
Pub Date : 2024-05-01 DOI: 10.1097/as9.0000000000000429
Tyler J. Loftus, M. Ruppert, B. Shickel, T. Ozrazgat-Baslanti, Jeremy A. Balch, Kenneth L. Abbott, Die Hu, Adnan Javed, Firas G Madbak, F. Guirgis, David Skarupa, P. Efron, P. Tighe, William R. Hogan, Parisa Rashidi, Gilbert R. Upchurch, A. Bihorac
To determine whether certain patients are vulnerable to errant triage decisions immediately after major surgery and whether there are unique sociodemographic phenotypes within overtriaged and undertriaged cohorts. In a fair system, overtriage of low-acuity patients to intensive care units (ICUs) and undertriage of high-acuity patients to general wards would affect all sociodemographic subgroups equally. This multicenter, longitudinal cohort study of hospital admissions immediately after major surgery compared hospital mortality and value of care (risk-adjusted mortality/total costs) across 4 cohorts: overtriage (N = 660), risk-matched overtriage controls admitted to general wards (N = 3077), undertriage (N = 2335), and risk-matched undertriage controls admitted to ICUs (N = 4774). K-means clustering identified sociodemographic phenotypes within overtriage and undertriage cohorts. Compared with controls, overtriaged admissions had a predominance of male patients (56.2% vs 43.1%, P < 0.001) and commercial insurance (6.4% vs 2.5%, P < 0.001); undertriaged admissions had a predominance of Black patients (28.4% vs 24.4%, P < 0.001) and greater socioeconomic deprivation. Overtriage was associated with increased total direct costs [$16.2K ($11.4K–$23.5K) vs $14.1K ($9.1K–$20.7K), P < 0.001] and low value of care; undertriage was associated with increased hospital mortality (1.5% vs 0.7%, P = 0.002) and hospice care (2.2% vs 0.6%, P < 0.001) and low value of care. Unique sociodemographic phenotypes within both overtriage and undertriage cohorts had similar outcomes and value of care, suggesting that triage decisions, rather than patient characteristics, drive outcomes and value of care. Postoperative triage decisions should ensure equality across sociodemographic groups by anchoring triage decisions to objective patient acuity assessments, circumventing cognitive shortcuts and mitigating bias.
目的是确定某些病人是否容易在大手术后立即受到错误分流决定的影响,以及在过度分流和分流不足的人群中是否存在独特的社会人口表型。 在一个公平的系统中,将低急症患者过度分流到重症监护室(ICU)和将高急症患者分流到普通病房会对所有社会人口亚群产生同等影响。 这项针对大手术后立即入院的多中心纵向队列研究比较了 4 个队列的住院死亡率和护理价值(风险调整后死亡率/总成本),这 4 个队列分别是:过度分流(660 人)、风险匹配的普通病房过度分流对照组(3077 人)、过度分流(2335 人)和风险匹配的重症监护病房过度分流对照组(4774 人)。K-均值聚类确定了过度接种和低度接种队列中的社会人口表型。 与对照组相比,过度分流的入院患者中男性患者居多(56.2% vs 43.1%,P < 0.001),且有商业保险(6.4% vs 2.5%,P < 0.001);分流不足的入院患者中黑人患者居多(28.4% vs 24.4%,P < 0.001),且社会经济贫困程度更高。过度接诊与直接总成本增加[1.62万美元(11.4-23.5万美元)vs 1.41万美元(9.1-20.7万美元),P < 0.001]和护理价值低有关;不足接诊与住院死亡率增加(1.5% vs 0.7%,P = 0.002)和临终关怀(2.2% vs 0.6%,P < 0.001)和护理价值低有关。过度分流和过度分流队列中的独特社会人口表型具有相似的治疗效果和护理价值,这表明分流决策而非患者特征决定了治疗效果和护理价值。 术后分流决策应确保不同社会人口群体之间的平等,将分流决策与客观的患者严重程度评估挂钩,避免认知上的捷径并减少偏见。
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引用次数: 0
Adequate Reporting Among Ventral Hernia Repair Operative Reports: A Cross-Sectional Study of Prevalence of Details and Association With Clinical Outcomes 腹股沟疝修补术手术报告中的充分报告:有关细节的普遍性及与临床结果的关系的横断面研究
Pub Date : 2024-04-23 DOI: 10.1097/as9.0000000000000425
Said Maldonado, N. Lyons, Jonathan S. Lall, J. S. Zimmerle, Brendan Rosamond, Ashlynn Mills, Yoolim Alex Seo, Angelica Calderon Rodriguez, Rainna Coelho, Natalia Cavagnaro, Zuhair Ali, M. K. Liang
We aimed to evaluate the prevalence of highly detailed ventral hernia repair (VHR) operative reports and associations between operative report detail and postoperative outcomes in a medico-legal dataset. VHR are one of the most common surgical procedures performed in the United States. Previous work has shown that VHR operative reports are poorly detailed, however, the relationship between operative report detail and patient outcomes is unknown. This is a retrospective cross-sectional observational study. Operative reports describing VHR were obtained from a medical-legal database. Medical records were screened and data was extracted including clinical outcomes, such as surgical site infection (SSI), hernia recurrence, and reoperation and the presence of key details in each report. Highly detailed operative reports were defined as having 70% of recommended details. The primary outcome was the prevalence of highly detailed VHR operative reports. A total of 1011 VHR operative reports dictated by 693 surgeons across 517 facilities in 50 states were included. Median duration of follow-up was 4.6 years after initial surgery. Only 35.7% of operative reports were highly detailed. More recent operative reports, cases with resident involvement, and contaminated procedures were more likely to be highly detailed (all P < 0.05). Compared to poorly detailed operative reports, cases with highly detailed reports had fewer SSIs (13.2% vs 7.5%, P = 0.006), hernia recurrence (65.8% vs 55.4%, P = 0.002), and reoperation (78.9% vs 62.6%, P = 0.001). In this medico-legal dataset, most VHR operative reports are poorly detailed while highly detailed operative reports were associated with lower rates of complications. Future studies should examine a nationally representative dataset to validate our findings.
我们的目的是评估高度详细的腹股沟疝修补术(VHR)手术报告的普遍性,以及医疗法律数据集中手术报告细节与术后结果之间的关联。 腹股沟疝修补术是美国最常见的外科手术之一。以往的研究表明,VHR 手术报告的详细程度很低,但手术报告的详细程度与患者预后之间的关系尚不清楚。 这是一项回顾性横断面观察研究。描述 VHR 的手术报告来自医疗法律数据库。筛选医疗记录并提取数据,包括临床结果,如手术部位感染(SSI)、疝气复发、再次手术以及每份报告中是否存在关键细节。高度详细的手术报告被定义为包含 70% 的建议细节。主要结果是高度详细的 VHR 手术报告的流行率。 美国 50 个州 517 家医疗机构的 693 名外科医生共撰写了 1011 份 VHR 手术报告。中位随访时间为首次手术后 4.6 年。只有 35.7% 的手术报告非常详细。较新的手术报告、有住院医师参与的病例和受污染的手术更有可能是高度详细的(所有 P < 0.05)。与不太详细的手术报告相比,报告高度详细的病例SSI(13.2% vs 7.5%,P = 0.006)、疝气复发(65.8% vs 55.4%,P = 0.002)和再次手术(78.9% vs 62.6%,P = 0.001)更少。 在这个医学法律数据集中,大多数 VHR 手术报告不够详细,而高度详细的手术报告与较低的并发症发生率相关。未来的研究应采用具有全国代表性的数据集来验证我们的发现。
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引用次数: 0
Response to: Comment on “Risk Models for Developing Pancreatic Fistula After Pancreatoduodenectomy: Validation in a Nationwide Prospective Cohort” 回应:关于 "胰十二指肠切除术后患胰瘘的风险模型:在全国性前瞻性队列中进行验证"
Pub Date : 2024-04-22 DOI: 10.1097/as9.0000000000000413
T. Schouten, A. C. Henry, F. Smits, L. Daamen, I. Molenaar, H. V. van Santvoort
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引用次数: 0
Clinical Applications of Machine Learning 机器学习的临床应用
Pub Date : 2024-04-18 DOI: 10.1097/as9.0000000000000423
N. Mateussi, Michael P. Rogers, Emily A. Grimsley, M. Read, Rajavi Parikh, Ricardo Pietrobon, Paul C. Kuo
This review introduces interpretable predictive machine learning approaches, natural language processing, image recognition, and reinforcement learning methodologies to familiarize end users. As machine learning, artificial intelligence, and generative artificial intelligence become increasingly utilized in clinical medicine, it is imperative that end users understand the underlying methodologies. This review describes publicly available datasets that can be used with interpretable predictive approaches, natural language processing, image recognition, and reinforcement learning models, outlines result interpretation, and provides references for in-depth information about each analytical framework. This review introduces interpretable predictive machine learning models, natural language processing, image recognition, and reinforcement learning methodologies. Interpretable predictive machine learning models, natural language processing, image recognition, and reinforcement learning are core machine learning methodologies that underlie many of the artificial intelligence methodologies that will drive the future of clinical medicine and surgery. End users must be well versed in the strengths and weaknesses of these tools as they are applied to patient care now and in the future.
本综述介绍了可解释的预测性机器学习方法、自然语言处理、图像识别和强化学习方法,以便终端用户熟悉这些方法。 随着机器学习、人工智能和生成式人工智能越来越多地应用于临床医学,终端用户必须了解其基本方法。 本综述介绍了可用于可解释预测方法、自然语言处理、图像识别和强化学习模型的公开数据集,概述了结果解释,并提供了有关每个分析框架深入信息的参考文献。 本综述介绍了可解释预测机器学习模型、自然语言处理、图像识别和强化学习方法。 可解释预测机器学习模型、自然语言处理、图像识别和强化学习是核心机器学习方法,是许多人工智能方法的基础,将推动未来临床医学和外科手术的发展。终端用户必须精通这些工具的优缺点,因为它们现在和将来都会被应用到病人护理中。
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引用次数: 0
Surgeon Preference and Clinical Outcome of 3D Vision Compared to 2D Vision in Laparoscopic Surgery: Systematic Review and Meta-Analysis of Randomized Trials 腹腔镜手术中 3D 视觉与 2D 视觉相比的外科医生偏好和临床结果:随机试验的系统回顾和元分析
Pub Date : 2024-04-15 DOI: 10.1097/as9.0000000000000415
R. Amiri, Maurice J. Zwart, Leia R. Jones, M. Abu Hilal, H. Beerlage, M. I. van Berge Henegouwen, W. Laméris, W. A. Bemelman, M. Besselink
To assess the added value of 3-dimensional (3D) vision, including high definition (HD) technology, in laparoscopic surgery in terms of surgeon preference and clinical outcome. The use of 3D vision in laparoscopic surgery has been suggested to improve surgical performance. However, the added value of 3D vision remains unclear as a systematic review of randomized controlled trials (RCTs) comparing 3D vision including HD technology in laparoscopic surgery is currently lacking. A systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines with a literature search up to May 2023 using PubMed and Embase (PROSPERO, CRD42021290426). We included RCTs comparing 3D versus 2-dimensional (2D) vision in laparoscopic surgery. The primary outcome was operative time. Meta-analyses were performed using the random effects model to estimate the pooled effect size expressed in standard mean difference (SMD) with corresponding 95% confidence intervals (CIs). The level of evidence and quality was assessed according to the Cochrane risk of bias tool. Overall, 25 RCTs with 3003 patients were included. Operative time was reduced by 3D vision (−8.0%; SMD, −0.22; 95% CI, −0.37 to −0.06; P = 0.007; n = 3003; 24 studies; I 2 = 75%) compared to 2D vision. This benefit was mostly seen in bariatric surgery (−16.3%; 95% CI, −1.28 to −0.21; P = 0.006; 2 studies; n = 58; I 2 = 0%) and general surgery (−6.7%; 95% CI, −0.34 to −0.01; P = 0.036; 9 studies; n = 1056; I 2 = 41%). Blood loss was nonsignificantly reduced by 3D vision (SMD, −0.33; 95% CI, −0.68 to 0.017; P = 0.060; n = 1830; I 2 = 92%). No differences in the rates of morbidity (14.9% vs 13.5%, P = 0.644), mortality (0% vs 0%), conversion (0.8% vs 0.9%, P = 0.898), and hospital stay (9.6 vs 10.5 days, P = 0.078) were found between 3D and 2D vision. In 15 RCTs that reported on surgeon preference, 13 (87%) reported that the majority of surgeons favored 3D vision. Across 25 RCTs, this systematic review and meta-analysis demonstrated shorter operative time with 3D vision in laparoscopic surgery, without differences in other outcomes. The majority of surgeons participating in the RCTs reported in favor of 3D vision.
从外科医生的偏好和临床效果的角度评估腹腔镜手术中三维(3D)视觉(包括高清(HD)技术)的附加值。 有人认为在腹腔镜手术中使用三维视觉可提高手术效果。然而,由于目前缺乏对腹腔镜手术中包括高清技术在内的三维视觉进行比较的随机对照试验(RCT)的系统回顾,因此三维视觉的附加值仍不明确。 根据系统综述和元分析首选报告项目(PRISMA)指南,我们利用 PubMed 和 Embase(PROSPERO,CRD42021290426)对截至 2023 年 5 月的文献进行了检索。我们纳入了比较腹腔镜手术中 3D 视觉与 2D 视觉的 RCT。主要结果是手术时间。我们使用随机效应模型进行了 Meta 分析,以标准均值差异 (SMD) 和相应的 95% 置信区间 (CI) 来估算汇总效应大小。证据水平和质量根据科克伦偏倚风险工具进行评估。 总共纳入了 25 项 RCT,共 3003 名患者。与二维视觉相比,三维视觉缩短了手术时间(-8.0%;SMD,-0.22;95% CI,-0.37 至 -0.06;P = 0.007;n = 3003;24 项研究;I 2 = 75%)。这种益处主要体现在减肥手术(-16.3%;95% CI,-1.28 到 -0.21;P = 0.006;2 项研究;n = 58;I 2 = 0%)和普通手术(-6.7%;95% CI,-0.34 到 -0.01;P = 0.036;9 项研究;n = 1056;I 2 = 41%)中。3D 视觉技术可显著减少失血量(SMD,-0.33;95% CI,-0.68 至 0.017;P = 0.060;n = 1830;I 2 = 92%)。在发病率(14.9% vs 13.5%,P = 0.644)、死亡率(0% vs 0%)、转院率(0.8% vs 0.9%,P = 0.898)和住院时间(9.6 vs 10.5 天,P = 0.078)方面,3D 和 2D 视觉没有发现差异。在 15 项报告了外科医生偏好的研究中,有 13 项(87%)报告称大多数外科医生偏好 3D 视觉。 这项系统性回顾和荟萃分析显示,在 25 项研究中,腹腔镜手术中使用 3D 视觉的手术时间更短,但其他结果没有差异。大多数参与研究实验的外科医生都表示支持 3D 视觉。
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Annals of Surgery Open
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