Pub Date : 2023-12-07DOI: 10.18499/2070-9277-2023-26-3-73-84
Alexander V. Guskov, Alexander A. Oleynikov, Alexander A. Nikiforov, Valeria G. Logunkova, Dmitry G. Zhukovets, Oksana A. Laut, Tatiana A. Vasileva
In the presented literature review, the issue of the influence of general somatic factors associated with diseases of the cardiovascular and endocrine systems on the success of dental implantation was studied. The issues of the relationship of systemic inflammatory processes and periodontal status with the dental health of patients with background pathologies associated with an imbalance of pro- and anti-inflammatory cytokines, insulin and glucose in the blood in diabetes mellitus and obesity, factors of endothelial dysfunction in atherosclerosis, hypertension and coronary heart disease are highlighted. Based on the analyzed information, it was confirmed that poor-quality history taking, the lack of a thorough diagnostic examination (biochemical blood test, coagulogram, reaction to the presence of specific infections and viral diseases), ignoring the need to correct existing local and systemic inflammatory phenomena before dental implantation can lead to a violation the process of osseointegration, the occurrence of peri-implantitis, implant rejection reactions. In this regard, it can be concluded that when planning complex dental treatment, attention should be paid not only to local dental symptoms, but also to the general history and laboratory data, which will improve the quality of dental implantation.
{"title":"Influence of factors of systemic inflammation and endothelial dysfunction in somatic pathologies on the success of dental implantation (literature review)","authors":"Alexander V. Guskov, Alexander A. Oleynikov, Alexander A. Nikiforov, Valeria G. Logunkova, Dmitry G. Zhukovets, Oksana A. Laut, Tatiana A. Vasileva","doi":"10.18499/2070-9277-2023-26-3-73-84","DOIUrl":"https://doi.org/10.18499/2070-9277-2023-26-3-73-84","url":null,"abstract":"In the presented literature review, the issue of the influence of general somatic factors associated with diseases of the cardiovascular and endocrine systems on the success of dental implantation was studied. The issues of the relationship of systemic inflammatory processes and periodontal status with the dental health of patients with background pathologies associated with an imbalance of pro- and anti-inflammatory cytokines, insulin and glucose in the blood in diabetes mellitus and obesity, factors of endothelial dysfunction in atherosclerosis, hypertension and coronary heart disease are highlighted. Based on the analyzed information, it was confirmed that poor-quality history taking, the lack of a thorough diagnostic examination (biochemical blood test, coagulogram, reaction to the presence of specific infections and viral diseases), ignoring the need to correct existing local and systemic inflammatory phenomena before dental implantation can lead to a violation the process of osseointegration, the occurrence of peri-implantitis, implant rejection reactions. In this regard, it can be concluded that when planning complex dental treatment, attention should be paid not only to local dental symptoms, but also to the general history and laboratory data, which will improve the quality of dental implantation.","PeriodicalId":503589,"journal":{"name":"Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139185684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-07DOI: 10.18499/2070-9277-2023-26-3-41-46
Anna L. Ermolovich, Eleanora G. Borisova, V. A. Zheleznyak, Julia A. Khrustaleva
The issues of the complexity of diagnosing diseases of the pulpoperiodontal complex of teeth of patients who had previously recovered from COVID-19, as well as the need to select the most adapted algorithm for the treatment of pathology, depending on the clinical manifestations in the oral cavity, were studied. An increase in the activity of opportunistic microorganisms, which normally do not show activity in the oral cavity, gives rise to the development of various pathologies of hard tissues of the teeth, the pulp and periodontium. The expediency and necessity of including in this category of patients, in addition to the standard dental examination, also additional examination methods (for example, blood test, bacterioscopy, bacteriological tests, testing of the microvasculature, and others) before the start of any dental treatment. Emphasis is placed on the elimination of a certain type of microorganism, identified with the help of additional examination methods, thereby preventing the occurrence of long-term complications after endodontic treatment of the tooth.
{"title":"THE SIGNIFICANCE OF BACTERIOSCOPY IN THE COMPLEX OF DIAGNOSTICS OF COMPLICATED FORMS OF DENTAL CARIES OF PATIENTS WHO PREVIOUSLY HAVE COVID-19","authors":"Anna L. Ermolovich, Eleanora G. Borisova, V. A. Zheleznyak, Julia A. Khrustaleva","doi":"10.18499/2070-9277-2023-26-3-41-46","DOIUrl":"https://doi.org/10.18499/2070-9277-2023-26-3-41-46","url":null,"abstract":"The issues of the complexity of diagnosing diseases of the pulpoperiodontal complex of teeth of patients who had previously recovered from COVID-19, as well as the need to select the most adapted algorithm for the treatment of pathology, depending on the clinical manifestations in the oral cavity, were studied. An increase in the activity of opportunistic microorganisms, which normally do not show activity in the oral cavity, gives rise to the development of various pathologies of hard tissues of the teeth, the pulp and periodontium. The expediency and necessity of including in this category of patients, in addition to the standard dental examination, also additional examination methods (for example, blood test, bacterioscopy, bacteriological tests, testing of the microvasculature, and others) before the start of any dental treatment. Emphasis is placed on the elimination of a certain type of microorganism, identified with the help of additional examination methods, thereby preventing the occurrence of long-term complications after endodontic treatment of the tooth.","PeriodicalId":503589,"journal":{"name":"Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)","volume":"22 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139185559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-07DOI: 10.18499/2070-9277-2023-26-3-14-18
Anton S. Valynov, Natalia V. Chirkova, Mikhail A. Kryuchkov, Natalia V. Primacheva, M. N. Bobeshko
Despite the rapid development of orthopedic dentistry and the release of a large number of materials used to fix fixed structures, it is impossible to single out among them an ideal one for every case. There are several classes with significantly different characteristics. Even representatives of the same group have significant differences in properties, which is associated with continuous work on the recipe to adapt to modern requirements. Every orthopedic dentist tries to choose for himself a material that satisfies all parameters, used in dental practice as a fixing fixed structures. He pays special attention not only to the convenience of working with cements or their physico-chemical, physico-mechanical properties, but also to its bioinertness and biocompatibility. To assess the effect of fixing materials on surrounding tissues, a comparative assessment was carried out with the measurement of the toxicity index of materials and the papillary-marginal-alveolar index (PMA).
{"title":"Investigation of the effect of fixing zinc-phosphate cements on the tissues surrounding a fixed denture structure","authors":"Anton S. Valynov, Natalia V. Chirkova, Mikhail A. Kryuchkov, Natalia V. Primacheva, M. N. Bobeshko","doi":"10.18499/2070-9277-2023-26-3-14-18","DOIUrl":"https://doi.org/10.18499/2070-9277-2023-26-3-14-18","url":null,"abstract":"Despite the rapid development of orthopedic dentistry and the release of a large number of materials used to fix fixed structures, it is impossible to single out among them an ideal one for every case. There are several classes with significantly different characteristics. Even representatives of the same group have significant differences in properties, which is associated with continuous work on the recipe to adapt to modern requirements. Every orthopedic dentist tries to choose for himself a material that satisfies all parameters, used in dental practice as a fixing fixed structures. He pays special attention not only to the convenience of working with cements or their physico-chemical, physico-mechanical properties, but also to its bioinertness and biocompatibility. To assess the effect of fixing materials on surrounding tissues, a comparative assessment was carried out with the measurement of the toxicity index of materials and the papillary-marginal-alveolar index (PMA).","PeriodicalId":503589,"journal":{"name":"Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139185569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-13DOI: 10.18499/2070-9277-2023-26-1-31-35
Anton S. Valynov, Angelina S. Ivanina
Improving the reliability of fixing fixed orthopedic structures of dentures is an urgent issue at all times. Due to the increase in the variety of materials in the modern world, the choice for dentists has become even more difficult. Various types of fixing materials are used in the clinic, and their choice depends on the specifics of the clinical situation and the material of the structure from which it is made. One of the types of cements are zinc-phosphate, which are used in practice for a long time and are characterized by sufficient adhesion strength. Representatives of this group have become less popular in the orthopedic dental clinic, since its properties are considered insufficiently satisfactory. Undoubtedly, any fixing material has both pros and cons. It is possible to get high-quality treatment with a dental prosthesis in the oral cavity if the fixing materials are correctly selected, the principles of preparation are observed and a high-quality adhesive protocol is performed. The article describes a study of the adhesive ability of individual zinc-phosphate cements, which was carried out in laboratory conditions at the technical base of LLC "Tselit" Voronezh. 30 teeth of the chewing group were used, which were divided into groups according to the use of materials: "NeoDent" LLC Celit, "VISCIN" LLC Raduga-R, "Adhesor" SpofaDental (Czech Republic). The strength of adhesion was studied using the method - shear test, which determines the strength of the connection of dentine tissue with zinc-phosphate cement.
{"title":"INVESTIGATION OF THE ADHESIVE ABILITY OF ZINC-PHOSPHATE CEMENTS TO THE DENTIN OF THE TOOTH","authors":"Anton S. Valynov, Angelina S. Ivanina","doi":"10.18499/2070-9277-2023-26-1-31-35","DOIUrl":"https://doi.org/10.18499/2070-9277-2023-26-1-31-35","url":null,"abstract":"Improving the reliability of fixing fixed orthopedic structures of dentures is an urgent issue at all times. Due to the increase in the variety of materials in the modern world, the choice for dentists has become even more difficult. Various types of fixing materials are used in the clinic, and their choice depends on the specifics of the clinical situation and the material of the structure from which it is made. One of the types of cements are zinc-phosphate, which are used in practice for a long time and are characterized by sufficient adhesion strength. Representatives of this group have become less popular in the orthopedic dental clinic, since its properties are considered insufficiently satisfactory. Undoubtedly, any fixing material has both pros and cons. It is possible to get high-quality treatment with a dental prosthesis in the oral cavity if the fixing materials are correctly selected, the principles of preparation are observed and a high-quality adhesive protocol is performed. The article describes a study of the adhesive ability of individual zinc-phosphate cements, which was carried out in laboratory conditions at the technical base of LLC \"Tselit\" Voronezh. 30 teeth of the chewing group were used, which were divided into groups according to the use of materials: \"NeoDent\" LLC Celit, \"VISCIN\" LLC Raduga-R, \"Adhesor\" SpofaDental (Czech Republic). The strength of adhesion was studied using the method - shear test, which determines the strength of the connection of dentine tissue with zinc-phosphate cement.","PeriodicalId":503589,"journal":{"name":"Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139359790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-13DOI: 10.18499/2070-9277-2023-26-1-15-22
Fatima S. Khubaeva, S. Garazha, E. Grishilova, E. Nekrasova, Ekaterina E. Ilyina
Inflammatory periodontal diseases remain an unsolved problem of modern medicine due to the high prevalence and insufficient effectiveness of treatment. The study examined the effectiveness of photodynamic and anti-inflammatory therapy in the treatment of chronic generalized periodontitis of moderate severity. The study material was the results of a comprehensive dental examination and treatment of 90 patients aged 30 to 49 years. For treatment, Asepta balm, photodynamic therapy (FotoSan 630 device), etoricoxib (Arcoxia) were used for follow-up periods of up to six months using periodontal indices. The high efficiency of treatment of chronic generalized periodontitis of moderate severity with a combination of photodynamic and anti-inflammatory therapy has been proven. This combination increased the effectiveness of treatment, compared with single-component antimicrobial therapy by 29.9%.
{"title":"EFFECTIVENESS OF TREATMENT OF CHRONIC GENERALIZED PERIODONTITIS USING PHOTODYNAMIC AND ANTI-INFLAMMATORY THERAPY","authors":"Fatima S. Khubaeva, S. Garazha, E. Grishilova, E. Nekrasova, Ekaterina E. Ilyina","doi":"10.18499/2070-9277-2023-26-1-15-22","DOIUrl":"https://doi.org/10.18499/2070-9277-2023-26-1-15-22","url":null,"abstract":"Inflammatory periodontal diseases remain an unsolved problem of modern medicine due to the high prevalence and insufficient effectiveness of treatment. The study examined the effectiveness of photodynamic and anti-inflammatory therapy in the treatment of chronic generalized periodontitis of moderate severity. The study material was the results of a comprehensive dental examination and treatment of 90 patients aged 30 to 49 years. For treatment, Asepta balm, photodynamic therapy (FotoSan 630 device), etoricoxib (Arcoxia) were used for follow-up periods of up to six months using periodontal indices. The high efficiency of treatment of chronic generalized periodontitis of moderate severity with a combination of photodynamic and anti-inflammatory therapy has been proven. This combination increased the effectiveness of treatment, compared with single-component antimicrobial therapy by 29.9%.","PeriodicalId":503589,"journal":{"name":"Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)","volume":"83 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139359958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-13DOI: 10.18499/2070-9277-2023-26-1-52-55
E. I. Ryabinina, Elena E. Zotova, Elena I. Peleshenko, Ekaterina S. Nasonova
Psoriasis is one of the most common dermatological diseases that significantly reduces the quality of life of patients. At the same time, about 70% of them need the use of external therapy. The aim of the study was to increase the degree of extraction of active substances from plant materials in order to improve the therapeutic properties of topical preparations for the treatment of psoriasis. For the treatment of psoriasis, it is necessary to use highly concentrated alkaloid extracts of celandine; for this, an 80% solution of acetic acid was used as an extractant.
{"title":"OBTAINING THE EXTRACT OF CHELIDONII MAJORIS L. AS A COMPONENT OF TOPICAL PREPARATIONS IN THE THERAPY OF PSORIASIS","authors":"E. I. Ryabinina, Elena E. Zotova, Elena I. Peleshenko, Ekaterina S. Nasonova","doi":"10.18499/2070-9277-2023-26-1-52-55","DOIUrl":"https://doi.org/10.18499/2070-9277-2023-26-1-52-55","url":null,"abstract":"Psoriasis is one of the most common dermatological diseases that significantly reduces the quality of life of patients. At the same time, about 70% of them need the use of external therapy. The aim of the study was to increase the degree of extraction of active substances from plant materials in order to improve the therapeutic properties of topical preparations for the treatment of psoriasis. For the treatment of psoriasis, it is necessary to use highly concentrated alkaloid extracts of celandine; for this, an 80% solution of acetic acid was used as an extractant.","PeriodicalId":503589,"journal":{"name":"Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139359832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-13DOI: 10.18499/2070-9277-2023-26-1-4-8
Ruslan T. Ramazanov, Daniil A. Redkov, Nushuravan T. Gasanov, Ekaterina А. Lis
A dentist-surgeon performs a large number of different surgical procedures. Despite the fact that in the 21st century, the level of dental care is high, the number of tooth extractions has not decreased. The main component of surgical work is the extraction of a tooth. The article analyzes the clinical and radiological control of the process of socket regeneration using A-PRF technology, in addition, an assessment of the opinion of doctors on the use of this technique of hole preservation after removal was carried out. In his practice, a dental surgeon often encounters complications after a tooth extraction operation, and in order to avoid them, it is necessary to carry out a set of measures aimed at improving the rehabilitation period, optimizing the reparative process and improving the results of surgical treatment. Based on the results of our work, we found that this technique is not popular among doctors, although it shows good results. When using A-PRF clot, the period of socket epithelialization is reduced, and early formation of a bone pattern is observed, which we do not observe in patients in whom this technique is not used. In order not to carry out repeated surgical reception in the future, it is necessary to think about early conservation.
{"title":"A-PRF AS AN ALTERNATIVE TO ALVEOLAR AUGMENTATION","authors":"Ruslan T. Ramazanov, Daniil A. Redkov, Nushuravan T. Gasanov, Ekaterina А. Lis","doi":"10.18499/2070-9277-2023-26-1-4-8","DOIUrl":"https://doi.org/10.18499/2070-9277-2023-26-1-4-8","url":null,"abstract":"A dentist-surgeon performs a large number of different surgical procedures. Despite the fact that in the 21st century, the level of dental care is high, the number of tooth extractions has not decreased. The main component of surgical work is the extraction of a tooth. The article analyzes the clinical and radiological control of the process of socket regeneration using A-PRF technology, in addition, an assessment of the opinion of doctors on the use of this technique of hole preservation after removal was carried out. In his practice, a dental surgeon often encounters complications after a tooth extraction operation, and in order to avoid them, it is necessary to carry out a set of measures aimed at improving the rehabilitation period, optimizing the reparative process and improving the results of surgical treatment. Based on the results of our work, we found that this technique is not popular among doctors, although it shows good results. When using A-PRF clot, the period of socket epithelialization is reduced, and early formation of a bone pattern is observed, which we do not observe in patients in whom this technique is not used. In order not to carry out repeated surgical reception in the future, it is necessary to think about early conservation.","PeriodicalId":503589,"journal":{"name":"Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139359816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-13DOI: 10.18499/2070-9277-2023-26-1-36-41
Irina A. Belenova, Myra T. Kopbaeva, Olesya B. Popova, Olga A. Smazhko
The article presents an overview of modern scientific literature on the problem of xerostomia and its etiopathogenetic connection with various general somatic diseases. To date, often the treatment of xerostomia is carried out as an independent disease, due to the failure to identify the underlying pathology. Often, ignorance of the causal relationship of various diseases, both somatic and psycho-emotional, leads to an incorrect diagnosis at a dental appointment and, as a result, an incorrect treatment plan, which leads to a deterioration in the patient's condition and the occurrence of complications. In this connection, the task of a modern dentist becomes urgent to establish the true cause of the pathology of the oral cavity and provide highly qualified treatment, according to the obtained diagnostic data.
{"title":"XEROSTOMIA AS AN IDIOPATHIC SYMPTOM IN DENTISTRY","authors":"Irina A. Belenova, Myra T. Kopbaeva, Olesya B. Popova, Olga A. Smazhko","doi":"10.18499/2070-9277-2023-26-1-36-41","DOIUrl":"https://doi.org/10.18499/2070-9277-2023-26-1-36-41","url":null,"abstract":"The article presents an overview of modern scientific literature on the problem of xerostomia and its etiopathogenetic connection with various general somatic diseases. To date, often the treatment of xerostomia is carried out as an independent disease, due to the failure to identify the underlying pathology. Often, ignorance of the causal relationship of various diseases, both somatic and psycho-emotional, leads to an incorrect diagnosis at a dental appointment and, as a result, an incorrect treatment plan, which leads to a deterioration in the patient's condition and the occurrence of complications. In this connection, the task of a modern dentist becomes urgent to establish the true cause of the pathology of the oral cavity and provide highly qualified treatment, according to the obtained diagnostic data.","PeriodicalId":503589,"journal":{"name":"Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139359912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-13DOI: 10.18499/2070-9277-2023-26-1-42-51
Elena F. Safonova, Lyudmila V. Rudakova, Elena A. Zheleznova, Yuliya O. Dyachenko-Kalyapina
The data of domestic and foreign literature characterizing the current state of pharmaceutical education are studied. The criteria for the effectiveness of the process of professional development of pharmaceutical industry specialists have been established. A sociological study of pharmaceutical workers on the demand and quality of pharmaceutical education received by them was conducted. Practical recommendations aimed at improving the process of professional development of pharmaceutical workers to improve the quality of pharmaceutical care are proposed.
{"title":"EVALUATION OF THE EFFECTIVENESS OF PROFESSIONAL TRAINING OF PHARMACEUTICAL SPECIALISTS VORONEZH","authors":"Elena F. Safonova, Lyudmila V. Rudakova, Elena A. Zheleznova, Yuliya O. Dyachenko-Kalyapina","doi":"10.18499/2070-9277-2023-26-1-42-51","DOIUrl":"https://doi.org/10.18499/2070-9277-2023-26-1-42-51","url":null,"abstract":"The data of domestic and foreign literature characterizing the current state of pharmaceutical education are studied. The criteria for the effectiveness of the process of professional development of pharmaceutical industry specialists have been established. A sociological study of pharmaceutical workers on the demand and quality of pharmaceutical education received by them was conducted. Practical recommendations aimed at improving the process of professional development of pharmaceutical workers to improve the quality of pharmaceutical care are proposed.","PeriodicalId":503589,"journal":{"name":"Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)","volume":"98 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139359792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-13DOI: 10.18499/2070-9277-2023-26-1-56-62
Olga K. Petrova, Irina I. Ivanova, Anna A. Shapovalova, A. Zyablov
The aim of the work was to create a piezoelectric sensor modified with a polymer with molecular imprints of cefuroxime for its subsequent determination in aqueous solutions. For the synthesis of MIP, we used a mixture containing a copolymer of 1,2,4,5-benzenetracarboxylic acid and 4,4'-diaminodiphenyl oxide produced by OJSC IIPP SPA Plastic (Moscow), as well as a solution containing template molecules. The resulting mixture was applied to the surface of the sensor electrode by stamping. After that, thermal imidization was carried out in an oven. Next, the sensors were cooled and placed in distilled water to remove the template. The resulting sensor was used to determine the content of the antibiotic cefuroxime in aqueous solutions using a calibration curve. For this, standard solutions of cefuroxime were prepared with concentrations of 1.0101 1.0107 g/dm3. The measurements made allowed us to conclude that with an increase in the antibiotic concentration in the analyzed solution, a decrease in the resonant frequency occurs. The calibration dependence is linear. The limit of detection of cefuroxime for the obtained sensor is 1.0105 g/dm3. To test the selectivity of the obtained sensor based on a polymer with molecular imprints, an analysis of an antibiotic similar in structure, cefazolin, was carried out. It has been established that the sensory system is selective only for the antibiotic that was used for the synthesis of MIP.
{"title":"DETERMINATION OF ANTIBIOTICS CEPHALOSPORIN SERIES WITH PIEZOELECTRIC SENSORS IN WATER SOLUTIONS","authors":"Olga K. Petrova, Irina I. Ivanova, Anna A. Shapovalova, A. Zyablov","doi":"10.18499/2070-9277-2023-26-1-56-62","DOIUrl":"https://doi.org/10.18499/2070-9277-2023-26-1-56-62","url":null,"abstract":"The aim of the work was to create a piezoelectric sensor modified with a polymer with molecular imprints of cefuroxime for its subsequent determination in aqueous solutions. For the synthesis of MIP, we used a mixture containing a copolymer of 1,2,4,5-benzenetracarboxylic acid and 4,4'-diaminodiphenyl oxide produced by OJSC IIPP SPA Plastic (Moscow), as well as a solution containing template molecules. The resulting mixture was applied to the surface of the sensor electrode by stamping. After that, thermal imidization was carried out in an oven. Next, the sensors were cooled and placed in distilled water to remove the template. The resulting sensor was used to determine the content of the antibiotic cefuroxime in aqueous solutions using a calibration curve. For this, standard solutions of cefuroxime were prepared with concentrations of 1.0101 1.0107 g/dm3. The measurements made allowed us to conclude that with an increase in the antibiotic concentration in the analyzed solution, a decrease in the resonant frequency occurs. The calibration dependence is linear. The limit of detection of cefuroxime for the obtained sensor is 1.0105 g/dm3. To test the selectivity of the obtained sensor based on a polymer with molecular imprints, an analysis of an antibiotic similar in structure, cefazolin, was carried out. It has been established that the sensory system is selective only for the antibiotic that was used for the synthesis of MIP.","PeriodicalId":503589,"journal":{"name":"Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139359846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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