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SELECTION OF A STRUCTURAL MATERIAL FOR THE BASIS OF A REMOVABLE PROSTHESIS IN PATIENTS WITH ORAL DYSBIOSIS BASED ON TOXICOLOGICAL EXAMINATION 根据毒理学检查为口腔菌群失调患者选择可摘义齿的基础结构材料
Pub Date : 2023-07-13 DOI: 10.18499/2070-9277-2023-26-1-9-14
Natalia V. Chirkova, Zhanna V. Vecherkina, Natalia A. Shalimova, Natalia V. Primacheva
It is proved that the tissues and organs of the oral cavity are normally in dynamic equilibrium with balanced biochemical processes that preserve tissue structures and support their function. The problem of the relationship of tissues and organs of the oral cavity with materials intended for the manufacture of dentures is one of the main problems in the clinic of orthopedic dentistry. Currently, acrylic plastics, the technological properties of which do not require expensive equipment, are most widely used in the manufacture of prosthetic structures. However, according to most experts, acrylic plastics have a number of significant drawbacks: the occurrence of toxic-allergic reactions, violation of the microflora of the oral cavity, the development of blastomatous growth in the tissues of the prosthetic bed. In order to increase the effectiveness of orthopedic treatment with removable dentures and reduce the intensity of the occurrence and development of oral dysbiosis and inflammatory reactions after prosthetics, the authors conducted biotesting of polymer materials of acrylic nature, the results of which are presented in this paper.
事实证明,口腔组织和器官通常处于动态平衡状态,其平衡的生化过程可保护组织结构并支持其功能。口腔组织和器官与制作假牙的材料之间的关系问题是口腔矫形诊所的主要问题之一。目前,丙烯酸塑料(其技术特性不需要昂贵的设备)被最广泛地应用于义齿结构的制造。然而,根据大多数专家的观点,丙烯酸塑料有许多明显的缺点:发生毒性过敏反应、破坏口腔微生物菌群、在修复床组织中出现胚芽生长。为了提高活动假牙矫形治疗的效果,减少修复后口腔菌群失调和炎症反应的发生和发展,作者对丙烯酸性质的聚合物材料进行了生物测试,结果见本文。
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引用次数: 0
EMPIRIC ANTIBIOTIC THERAPY OF ACUTE INFLAMMATORY PROCESSES OF THE FACE AND NECK IN CHILDREN AT THE OUTPATIENT STAGE, BASED ON THE RESULTS OF BACTERIOLOGICAL MONITORING OF THE DEPARTMENT OF MAXILLOFACIAL SURGERY. 根据颌面外科细菌学监测结果,在门诊阶段对儿童面部和颈部急性炎症过程进行经验性抗生素治疗。
Pub Date : 2023-07-13 DOI: 10.18499/2070-9277-2023-26-1-23-30
Dmitriy Yu. Kharitonov, I. V. Korytina, Nonna A. Nazareva, Margarita A. Agapova
Based on the analysis of bacteriological cultures of the wound discharge according to archival data of the case histories of patients with acute inflammatory processes of the face and neck on the basis of the Department of Maxillofacial Surgery of the Voronezh Regional Children's Clinical Hospital No. 2, data were obtained on microbiological pathogens and their sensitivity to various antibacterial drugs. Monitoring was carried out and the pathogen was classified in the main inflammatory processes of the face and neck in children from 1 to 15 years old. Based on the results obtained, we have developed and proposed schemes for empirical antibiotic therapy for use by pediatric dentists and pediatricians on an outpatient basis. The most relevant for outpatient applications are oral antibiotics with high bioavailability and efficacy against etiological pathogens.
沃罗涅日州第二儿童临床医院颌面外科根据脸部和颈部急性炎症患者病史档案资料对伤口分泌物进行细菌培养分析,在此基础上获得了微生物病原体及其对各种抗菌药物敏感性的数据。对 1 至 15 岁儿童面部和颈部的主要炎症过程进行了监测和病原体分类。根据所得结果,我们制定并提出了经验性抗生素治疗方案,供儿童牙医和儿科医生在门诊使用。最适合门诊应用的是生物利用度高、对病原体有效的口服抗生素。
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引用次数: 0
STUDY OF CLINICAL AND MICROBIOLOGICAL PARAMETERS IN PATIENTS WITH NON-REMOVABLE ORTHODONTIC EQUIPMENT DURING THE USE OF DENTAL GELS IN A COMPARATIVE ASPECT 在使用牙科凝胶期间对使用不可拆卸正畸设备的患者的临床和微生物参数进行比较研究
Pub Date : 2023-07-01 DOI: 10.18499/2070-9277-2023-26-2-40-45
Anastasia G. Lesteva, Irina V. Firsova, O. Strusovskaya
Inflammatory periodontal disease is the second most common pathology after dental caries, affecting up to 95% of the population of different age groups. The main etiological factor in the occurrence of this pathology is periodontopathogenic microflora. During orthodontic intervention, there is an exacerbation of inflammatory processes in the periodontium due to the accumulation of microbial biofilm, due to the appearance in the oral cavity of patients of additional retention sites in the form of fixed structures. The use of conventional hygiene products is not enough to eliminate deposits of microbial origin. Therefore, to reduce the inflammatory process in the periodontium during orthodontic intervention, it is necessary to use additional hygiene products that provide an adequate antimicrobial effect. These funds should mainly have a specific effect on the periodontopathogenic microflora. In the course of the conducted studies, the effectiveness of the antimicrobial action of dental gels "Bergisept" and "Metrogil-Denta" was proved. At the same time, "Bergisept-gel" has the advantages of specifically inhibiting the growth of P. gingivalis and A. actinomycetemcomitans and practically does not have an antimicrobial effect against Str. salivarius.
炎症性牙周病是仅次于龋齿的第二大常见病,在不同年龄段的人群中发病率高达 95%。发生这种病症的主要病因是牙周致病微生物菌群。在正畸干预期间,由于患者口腔中出现了额外的固定结构形式的固位点,微生物生物膜的积累导致牙周炎症过程加剧。使用传统的卫生用品不足以消除微生物源性沉积物。因此,为了减少正畸干预期间牙周的炎症过程,有必要使用具有充分抗菌效果的额外卫生用品。这些资金应主要对牙周致病微生物菌群产生特定的影响。在研究过程中,"Bergisept "和 "Metrogil-Denta "牙科凝胶的抗菌效果得到了证实。同时,"Bergisept-凝胶 "的优点是能特别抑制牙龈脓疱疮杆菌和放线菌的生长,而对唾液酸链球菌几乎没有抗菌作用。
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引用次数: 0
COMPARATIVE CHARACTERISTICS OF PREPARATIONS BASED ON ROSEHIP FRUITS 玫瑰果制剂的比较特性
Pub Date : 2023-07-01 DOI: 10.18499/2070-9277-2023-26-2-101-110
Elena E. Zotova, E. I. Ryabinina, Алина F. Livanova, Anastasia D. Salnikova
The paper presents a comparative analysis of preparations based on rosehip fruits available on the Russian market in order to determine the effectiveness and expediency of choosing a drug. It is shown that the expediency of choosing a drug should first of all be determined by the purpose of use, despite the fact that all drugs, in addition to specific action, exhibit similar biological activity due to the content of vitamin C and other biologically active substances (BAS), which, depending on the variety of rosehip and the method of preparation of drugs, are still in them in different quantities. For the treatment of skin diseases, it is necessary to choose oils rich in PUFA and vitamin E. For the treatment of liver diseases, you should choose low-vitamin rosehip fruits or syrups based on it, which contain the largest amount of organic acids compared to other drugs. Among the natural preparations of the group of restorative and immunomodulatory effects, the most effective were rosehip fruits and water-soluble dry extract. In addition, it has been experimentally shown that all preparations from this group, except syrups, have adsorption activity against lead ions, which expands the list of useful properties of preparations based on rosehip fruits and increases the effectiveness of their use.
本文对俄罗斯市场上基于玫瑰果的制剂进行了比较分析,以确定选择药物的有效性和便利性。结果表明,选择药物的适宜性首先应根据使用目的来确定,尽管所有药物除具有特定作用外,还因含有维生素 C 和其他生物活性物质 (BAS) 而表现出相似的生物活性,但根据玫瑰果的品种和药物制剂方法的不同,其含量也不同。治疗皮肤病时,必须选择富含 PUFA 和维生素 E 的油。治疗肝病时,应选择低维生素的玫瑰果或以其为基础的糖浆,因为与其他药物相比,它们含有最多的有机酸。在具有恢复和免疫调节作用的天然制剂中,最有效的是玫瑰果和水溶性干提取物。此外,实验表明,除糖浆外,该组中的所有制剂都具有对铅离子的吸附活性,这扩大了以玫瑰果为基础的制剂的有用特性清单,并提高了其使用效果。
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引用次数: 0
AESTHETIC RESTORATION OF TEETH IN A PATIENT WITH ABFRACTION DEFECTS (CASE REPORT) 对一名牙齿缺损患者的牙齿进行美学修复(病例报告)
Pub Date : 2023-07-01 DOI: 10.18499/2070-9277-2023-26-2-67-72
A. Shashmurina, Aleksandr I. Nikolaev
In detail, at the expert level, a clinical example of aesthetic restoration of teeth with abfraction defects is considered. The medical and technological features of cavity preparation, modified adhesive processing, modeling, grinding and polishing of restorations are described in detail. Long-term results up to 6 years were analyzed. The plan for further supervision of the patient was considered.
在专家层面上,详细介绍了对有缺损的牙齿进行美学修复的临床实例。详细介绍了牙洞预备、改良粘接剂处理、模型制作、修复体打磨和抛光的医学和技术特点。分析了长达 6 年的长期效果。还考虑了对患者进行进一步监护的计划。
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引用次数: 0
INDICATORS OF OXYGEN ABSORPTION IN TESTICULAR TISSUES UNDER THE INFLUENCE OF INCORPORATION 137CS 掺入 137cs 影响下的睾丸组织氧气吸收指标
Pub Date : 2023-07-01 DOI: 10.18499/2070-9277-2023-26-2-92-100
Mohanad A. Al Meselmani
The results of assessing the effect of caesium-137 radionuclide, with a specific activity of 3300 Bq/kg, on oxygen consumption by rat testicular tissues. A significant increase in the rate of oxygen consumption was demonstrated on both endogenous and exogenous substrates. The maximum increase in tissue respiration was noted against the background of the use of glutamate as an exogenous substrate. Signs of disconnection of oxidative phosphorylation processes with the use of 2,4-dinitrophenol have been recorded, as well as inhibitory analysis confirms a decrease in the intensity of NAD-dependent oxidation Thus, the oral intake of caesium-137 into the body of rats with a specific activity of 3300 Bq / kg poses a danger to the male reproductive system.
比活度为 3300 Bq/kg 的铯-137 放射性核素对大鼠睾丸组织耗氧量影响的评估结果。结果表明,在内源性和外源性底物的作用下,大鼠睾丸组织的耗氧量明显增加。在使用谷氨酸作为外源底物的情况下,组织呼吸的增加幅度最大。使用 2,4-二硝基苯酚后,氧化磷酸化过程出现了中断迹象,抑制分析也证实了 NAD 依赖性氧化作用强度的下降。
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引用次数: 0
ELECTRICAL CONDUCTIVITY OF HUMAN TOOTH ENAMEL AFTER EXPOSURE TO CHEMICAL OR PHYSICAL FACTORS WHEN FIXING ELEMENTS OF A MULTIBONDING 在固定多粘结剂元件时,人的牙釉质在受到化学或物理因素影响后的导电性能
Pub Date : 2023-07-01 DOI: 10.18499/2070-9277-2023-26-2-4-10
Yuri A. Ippolitov, Svetlana A. Mikhailova, Ivan Yu. Ippolitov, Elena O. Aleshina, Aleksey V. Gylov, Abbas A. Mahmoudi, Maher A. Solаiman, Viktoria P. Kuralesina
When using multibonding fixed orthodontic equipment, complications are possible mainly associated with the occurrence of tooth enamel caries, despite the presence of a large selection of means for the prevention of dental diseases. During the complex treatment of patients with dental deformities, 2 clinical groups were identified and the enamel surface was treated with 37% orthophosphoric acid and an erbium dental laser with a wavelength of 2940nm - (power 2 W, water 20%, air 75%, tip: BOOST with nozzle H 6/8, laser beam perpendicular to the enamel at a distance of 5 mm from its surface), before fixing the removable bracket element with orthodontic glue (A16.07.048). The conducted studies have shown that after laser preparation in the etching of enamel with acid, the surface acquires roughness, unevenness with the exposure of numerous micropores, in particular the mouths of enamel channels, which increases the electrical conductivity of enamel and electrometric indicators reach 1.3(0.9; 1.5) mkA from the initial 0.15(0.1;0.2)mkA, whereas after processing the enamel with high-intensity laser light, these values were 0.3 (0.1; 0.4) mkA from the initial 0.15 (0.1; 0.2)mkA, due to the mineral saturation of the interstitial spaces of enamel, the mouths of enamel channels sealed with an organo-mineral complex, which reduces the possibility of its subsurface microbial demineralization.
在使用多粘结固定正畸设备时,尽管有多种预防牙病的方法可供选择,但可能出现的并发症主要与牙釉质龋齿的发生有关。在对牙齿畸形患者进行综合治疗期间,确定了两组临床患者,在用正畸胶水(A16.07.048)固定可移动托槽元件之前,用 37% 的正磷酸和波长为 2940nm 的铒牙科激光(功率 2 W,水 20%,空气 75%,喷嘴:BOOST,喷嘴 H 6/8,激光束垂直于牙釉质,距离牙釉质表面 5 mm)对牙釉质表面进行了处理。 已进行的研究表明,在用酸蚀刻珐琅质的激光制备过程中,珐琅质表面会变得粗糙、不平整,暴露出许多微孔,特别是珐琅质通道口,这增加了珐琅质的导电性,电学指标从最初的 0.15(0.1;0.2) mkA 达到 1.3(0.9; 1.5) mkA。2)mkA,而用高强度激光处理釉质后,这些数值从最初的0.15(0.1;0.2)mkA下降到0.3(0.1;0.4)mkA,这是由于釉质间隙的矿物质饱和,釉质通道口被有机矿物质复合物封住,降低了其表层下微生物脱矿的可能性。
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引用次数: 0
X-RAY ASSESSMENT OF THE OROANTRAL COMMUNICATION POTENTIAL RISK IN PATIENTS DEPENDING ON GENDER 根据性别对患者口腔内沟通的潜在风险进行 X 射线评估
Pub Date : 2023-07-01 DOI: 10.18499/2070-9277-2023-26-2-35-39
R. A. Zhidkov, A. M. Tsitsiashvili, Yuri L. Vasiliev, Andrey M. Panin, Dmitry A. Lezhnev
Tooth extraction is the most common operation in the practice of a dentist-surgeon. With the increase in the number of surgical interventions, the number of complications also increases, one of which is the occurrence of an oroantral communication with the maxillary sinus. Knowing the causes and patterns of the prevalence of potential risk factors can significantly reduce the number of complications. Thus, the need to diagnose the presence of a potential risk of an oroantral communication formation comes to the fore. Cone beam computed tomography is the most informative and accessible method of radiodiagnosis of the relative position of the upper jaw teeth roots and maxillary sinus. This article presents the results of a study of the dependence of potential anatomical risk factors on the patient's gender according to cone-beam computed tomography.
拔牙是牙科外科医生最常见的手术。随着手术数量的增加,并发症的数量也随之增加,其中之一就是与上颌窦发生口腔外沟通。了解潜在危险因素的原因和流行模式可以大大减少并发症的发生。因此,诊断是否存在形成口腔窦沟通的潜在风险就显得尤为重要。锥形束计算机断层扫描是对上颌牙根和上颌窦的相对位置进行放射诊断的最翔实、最便捷的方法。本文介绍了根据锥形束计算机断层扫描对潜在的解剖风险因素与患者性别的关系进行研究的结果。
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引用次数: 0
THE EFFECTIVENESS OF THE COMPOSITION IN THE FORM OF GEL FOR ORAL CARE WITH HERBAL COMPONENTS 含草药成分的口腔护理凝胶形式组合物的功效
Pub Date : 2023-07-01 DOI: 10.18499/2070-9277-2023-26-2-59-66
Irina I. Latif, Aleksandr M. Kovalevsky, Lyudmila A. Kraeva, Maria A. Nosova, Aleksey N. Sharov
The article discusses the results of a clinical and microbiological study of the anti-plaque, anti-inflammatory, hemostatic, antibacterial and anti-adhesive effects of the developed composition in the form of a gel for the care of oral tissues based on aspen bark extract, chlorophyll, dihydroquercitin, D-panthenol, methyl salicylate, the effect of this complex on the pH level of the gingival fluid, the results of a microbiological study to determine the survival of microorganisms such as Streptococcus sanguinis, Streptococcus mitis, Streptococcus oralis, Streptococcus salivarius, Staphylococcus aureus, Enterococcus faecalis, Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii, the results of determining the adhesive properties of S. Sanguinis in the presence of a gel composition, the effectiveness of the reduction action indices ONi-S, SBI, PMA, changes in the pH level of gingival fluid, antibacterial and anti-adhesive efficiancy.
文章论述了以杨树皮提取物、叶绿素、二氢槲皮素、D-泛醇、水杨酸甲酯为基础开发的用于口腔组织护理的凝胶形式组合物的抗斑块、消炎、止血、抗菌和抗粘连效果的临床和微生物学研究结果,以及这种复合物对牙龈液 pH 值的影响、微生物学研究的结果,以确定血链球菌、肝炎链球菌、口腔链球菌、唾液链球菌、金黄色葡萄球菌、粪肠球菌、肺炎克雷伯氏菌、铜绿假单胞菌、鲍曼不动杆菌等微生物的存活率;确定 S. Sanguinis(血链球菌)在复合物中的粘附性的结果;确定 S. Sanguinis(肝炎链球菌)在复合物中的粘附性的结果;确定 S. Sanguinis(血链球菌)在复合物中的粘附性的结果;确定 S. Sanguinis(肝炎链球菌)在复合物中的粘附性的结果。在凝胶成分存在的情况下,确定 Sanguinis 的粘附性、ONi-S、SBI、PMA 的还原作用指数的有效性、牙龈液 pH 值的变化、抗菌和抗粘附功效。
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引用次数: 0
DENTAL STATUS FEATURES OF PATIENTS WITH ABFRACTION DEFECTS OF TEETH 牙齿缺损患者的牙齿状况特征
Pub Date : 2023-07-01 DOI: 10.18499/2070-9277-2023-26-2-46-52
A. Shashmurina, Ekaterina I. Gladarevskaya, Svetlana G. Danilenko, Aleksandr I. Nikolaev
The features of the dental status of 128 patients aged 30-49 years with abfraction defects of the teeth were studied. Complaints and anamnestic data, presumably related to the presence of abfraction defects, were recorded. An objective assessment of the severity of hyperesthesia of hard tissues of 193 teeth with abfraction defects in 128 patients was carried out using the Schiff air test. In the examined patients in the area of abfraction defects, a high prevalence of hyperesthesia of teeth necks (92.9%), enamel cracks (69.5%), gum recession without signs of inflammation of the gingival margin (89.1%), the presence of functional overload of teeth with abfraction defects (87.5%). In the study of 75.1% of teeth with abfraction defects, a high degree of hyperesthesia (2-3 points on the Schiff scale) was recorded. Hyperesthesia of the cervical region of the teeth is the leading symptom of abfraction defects, its predictable and guaranteed elimination during direct composite restoration is an urgent task in the complex treatment of these patients.
研究了 128 名年龄在 30-49 岁之间的牙齿屈曲缺损患者的牙齿状况特征。研究还记录了可能与牙齿缺损有关的主诉和异常数据。使用希夫空气测试法对 128 名患者的 193 颗有折叠缺损的牙齿硬组织过度麻醉的严重程度进行了客观评估。在接受检查的患者中,在屈曲缺损区域,牙颈部过度刺激(92.9%)、牙釉质裂缝(69.5%)、牙龈退缩(89.1%)、牙龈边缘无炎症迹象、屈曲缺损牙齿功能超负荷(87.5%)的发生率很高。在对 75.1%的屈曲缺损牙进行的研究中,记录到了高度的过度紧张(希夫量表上的 2-3 分)。牙颈部的过度收缩是折叠缺损的主要症状,在直接复合材料修复过程中可预测并确保消除这种过度收缩是对这些患者进行复杂治疗的当务之急。
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引用次数: 0
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Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)
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