Medical image registration has important applications in medical image analysis. Although deep learning-based registration methods are widely recognized, there is still performance improvement space for existing algorithms due to the complex physiological structure of brain images. In this paper, we aim to propose a deformable medical image registration method that is highly accurate and capable of handling complex physiological structures. Therefore, we propose DFMNet, a dual-channel fusion method based on GMamba, to achieve accurate brain MRI image registration. Compared with state-of-the-art networks like TransMorph, DFMNet has a dual-channel network structure with different fusion strategies. We propose the GMamba block to efficiently capture the remote dependencies in moving and fixed image features. Meanwhile, we propose a context extraction channel to enhance the texture structure of the image content. In addition, we designed a weighted fusion block to help the features of the two channels can be fused efficiently. Extensive experiments on three public brain datasets demonstrate the effectiveness of DFMNet. The experimental results demonstrate that DFMNet outperforms multiple current state-of-the-art deformable registration methods in structural registration of brain images.
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