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Information Retrieval in Biomedicine: Natural Language Processing for Knowledge Integration (Prince, V. and Roche, M.; 2009) [Book Reviews] 生物医学信息检索:知识整合的自然语言处理(Prince, V. and Roche, M.;2009)[书评]
Pub Date : 2010-03-18 DOI: 10.1109/MEMB.2009.935707
Zhengwu Lu
Natural language processing (NLP) is a subfield of computational sciences addressing the operation and management of texts as inputs or outputs of computational devices. The reviewed book is an excellent resource for researchers or graduate students interested in NLP, artificial intelligence, and linguistics, as well as those interested in the most recent advances in information management and retrieval in a health-care setting.
自然语言处理(NLP)是计算科学的一个分支领域,研究文本作为计算设备的输入或输出的操作和管理。对于对NLP、人工智能和语言学感兴趣的研究人员或研究生,以及对医疗保健环境中信息管理和检索的最新进展感兴趣的人来说,这本书评是一本极好的资源。
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引用次数: 0
Dysphonic speech reconstruction: construction of a novel system for effective and efficient communication. 不发音语音重建:为有效和高效的交流构建一个新的系统。
Pub Date : 2010-03-01 DOI: 10.1109/MEMB.2009.935725
H Irem Turkmen, M Elif Karsligil

In this article, a MELP-based real-time system that produces synthetic speech for patients with chronic dysphonia while preserving their continual structure of speech, was presented. Dysphonic patients, even though strained, could express themselves within face-to-face communications. However, when speaking in a group or using communication devices such as mobile phones, they face serious difficulties in vocal communication since it becomes harder to understand their speech. This system will make the speech of such a patient much more understandable by reconstructing the patients' dysphonic speech in real time. This system can easily be fitting into an embedded system of the size and shape of a mobile phone, so that it could be carried all the time by the patients.

本文介绍了一种基于melp的实时系统,该系统可以为慢性语音障碍患者产生合成语音,同时保持其连续的语音结构。语音障碍患者,即使紧张,也能在面对面的交流中表达自己。然而,当在群体中讲话或使用手机等通信设备时,他们的声音交流面临严重困难,因为他们的讲话变得更加难以理解。该系统通过对患者语音的实时重构,使患者的语音更加易于理解。这个系统可以很容易地安装到一个手机大小和形状的嵌入式系统中,这样病人就可以随时携带它。
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引用次数: 2
Clinical appointment process: improvement through schedule defragmentation. 临床预约流程:通过日程整理改进。
Pub Date : 2010-03-01 DOI: 10.1109/MEMB.2009.935718
Jie Lian, Kori Distefano, Somer D Shields, Cindy Heinichen, Melissa Giampietri, Lian Wang

Most clinics rely on the appointment scheduling systems to manage patients' access to their health-care providers. Conventional appointment scheduling processes have intrinsic inefficiency because of the tendency to generate fragmented time slots. In this article, a solution, which considers patient-provider mutual preference, is provided to guide the appointment scheduling process by means of schedule defragmentation. Computer simulation shows that patient-provider cooperation can effectively reduce schedule fragmentation, yielding higher appointment acceptance rate and clinic time utilization rate at given appointment demand matched by service supply. When service time distribution can be accurately estimated, decreasing unit time slot size may further improve the appointment scheduling efficiency. In addition, a clinical survey was conducted to identify the opportunities and challenges of applying the proposed defragmentation method in clinical appointment scheduling practice.

大多数诊所依靠预约调度系统来管理患者对医疗保健提供者的访问。传统的预约调度过程具有内在的低效率,因为往往会产生碎片化的时间段。在本文中,提供了一种考虑患者-提供者相互偏好的解决方案,通过计划碎片整理来指导预约调度过程。计算机仿真结果表明,医患合作可以有效减少日程碎片化,在预约需求与服务供给相匹配的情况下,获得更高的预约接受率和门诊时间利用率。在能够准确估计服务时间分布的情况下,减小单位时隙大小可以进一步提高预约调度效率。此外,还进行了一项临床调查,以确定在临床预约调度实践中应用所提出的碎片整理方法的机会和挑战。
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引用次数: 15
Clustering techniques: measuring the performance of contract service providers. 聚类技术:衡量合同服务提供者的绩效。
Pub Date : 2010-03-01 DOI: 10.1109/MEMB.2009.935708
Antonio Miguel Cruz, Sandra Patricia Usaquén Perilla, Nidia Nelly Vanegas Pabón

This paper investigates the use of clustering technique to characterize the providers of maintenance services in a health-care institution according to their performance. A characterization of the inventory of equipment from seven pilot areas was carried out first (including 264 medical devices). The characterization study concluded that the inventory on a whole is old [exploitation time (ET)/useful life (UL) average is 0.78] and has high maintenance service costs relative to the original cost of acquisition (service cost /acquisition cost average 8.61%). A monitoring of the performance of maintenance service providers was then conducted. The variables monitored were response time (RT), service time (ST), availability, and turnaround time (TAT). Finally, the study grouped maintenance service providers into clusters according to performance. The study grouped maintenance service providers into the following clusters. Cluster 0: Identified with the best performance, the lowest values of TAT, RT, and ST, with an average TAT value of 1.46 days; Clusters 1 and 2: Identified with the poorest performance, highest values of TAT, RT, and ST, and an average TAT value of 9.79 days; and Cluster 3: Identified by medium-quality performance, intermediate values of TAT, RT, and ST, and an average TAT value of 2.56 days.

本文研究了使用聚类技术,以表征维护服务的提供者在医疗保健机构根据他们的表现。首先对七个试点地区的设备库存(包括264个医疗装置)进行了特征描述。表征研究得出的结论是,库存总体上是旧的[开发时间(ET)/使用寿命(UL)平均值为0.78],相对于原始购置成本(服务成本/购置成本平均值为8.61%),维护服务成本较高。然后对维修服务供应商的表现进行了监测。监测的变量包括响应时间(RT)、服务时间(ST)、可用性和周转时间(TAT)。最后,研究将维护服务提供商根据性能分组为集群。该研究将维护服务提供商分为以下几类。集群0:性能最佳,TAT、RT、ST值最低,平均TAT值为1.46天;集群1和集群2:表现最差,TAT、RT和ST值最高,平均TAT值为9.79天;集群3:性能中等,TAT、RT、ST值居中,平均TAT值为2.56天。
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引用次数: 11
medical devices in cinema [Point of view] 电影院内的医疗器材[观点]
Pub Date : 2010-03-01 DOI: 10.1109/MEMB.2009.935724
G. Baura
Is it time to take a more sophisticated approach to the way we portray medical devices in American cinema?
是时候采取更复杂的方法来描绘美国电影中的医疗设备了吗?
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引用次数: 0
Quest for the artificial pancreas: combining technology with treatment. 探索人工胰腺:技术与治疗相结合。
Pub Date : 2010-03-01 DOI: 10.1109/MEMB.2009.935711
Rebecca A Harvey, Youqing Wang, Benyamin Grosman, Matthew W Percival, Wendy Bevier, Daniel A Finan, Howard Zisser, Dale E Seborg, Lois Jovanovic, Francis J Doyle, Eyal Dassau

The various components of the artificial pancreas puzzle are being put into place. Features such as communication, control, modeling, and learning are being realized presently. Steps have been set in motion to carry the conceptual design through simulation to clinical implementation. The challenging pieces still to be addressed include stress and exercise; as integral parts of the ultimate goal, effort has begun to shift toward overcoming the remaining hurdles to the full artificial pancreas. The artificial pancreas is close to becoming a reality, driven by technology, and the expectation that lives will be improved.

人造胰腺之谜的各个组成部分正在就位。目前正在实现通信、控制、建模和学习等功能。将概念设计通过模拟进行临床实施的步骤已经开始。仍然需要解决的挑战包括压力和锻炼;作为最终目标的组成部分,努力已经开始转向克服剩余的障碍,以实现完整的人工胰腺。在科技的推动下,人工胰腺即将成为现实,人们的生活也将得到改善。
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引用次数: 97
A novel phototherapy device: the design community approach for the developing world. 一种新型光疗装置:面向发展中国家的设计社区方法。
Pub Date : 2010-03-01 DOI: 10.1109/MEMB.2010.936453
Robert Malkin, Vijay Anand

Phototherapy is the standard treatment for severe cases of hyperbilirubinemia in newborns. Phototherapy exposes the infants to light in the range of 400-500 nm to isomerize unconjugated bilirubin in the skin. Any light source that produces this wavelength can be used, including the sun (though there is a risk of sunburn), fluorescent or halogen lamps, or, more recently, light-emitting diodes. Despite the well-established efficacy of phototherapy devices and their relative simplicity-being not much more than a floor lamp-phototherapy devices are too expensive for developing world hospitals to purchase, with typical hospital models ranging from US$3,000 to US$5,000. In addition, the resource-poor setting presents a more challenging engineering problem than most. Phototherapy devices are frequently donated to developing world hospitals. However, donated phototherapy devices typically run for no more than a few months once donated and, even then, offer little value to some hospitals. Given this background, we set out to design a phototherapy device specifically for use in the developing world. As a minimum, we knew that it had to have a light source with an extraordinarily long life span and have battery backup so that it could run during frequent power outages. Our design uses LEDs and is powered by a car or motorcycle battery. In this article, we present the full engineering design cycle, staring with needs identification and continuing through several cycles of engineering field trials and results with comments on the differences between the engineering design cycle executed in, and for, the developing world.

光疗是新生儿重症高胆红素血症的标准治疗方法。光疗将婴儿暴露在400-500纳米范围内的光下,使皮肤中的未共轭胆红素异构化。任何产生这种波长的光源都可以使用,包括太阳(尽管有晒伤的风险),荧光灯或卤素灯,或者最近的发光二极管。尽管光疗设备的功效已得到公认,而且它们相对简单——比落地灯多不了多少——但对于发展中国家的医院来说,光疗设备过于昂贵,无法购买,典型的医院型号从3000美元到5000美元不等。此外,资源贫乏的环境比大多数情况下更具挑战性的工程问题。光疗设备经常被捐赠给发展中国家的医院。然而,捐赠的光疗设备一旦捐赠,通常运行不超过几个月,即使这样,对一些医院也没有什么价值。在这样的背景下,我们着手设计一种专门用于发展中国家的光疗设备。至少,我们知道它必须有一个寿命非常长的光源,并有备用电池,这样它就可以在经常停电的情况下运行。我们的设计使用led,由汽车或摩托车电池供电。在本文中,我们介绍了完整的工程设计周期,从需求识别开始,继续通过工程现场试验的几个周期,并对在发展中国家和为发展中国家执行的工程设计周期之间的差异进行了评论。
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引用次数: 19
Wireless sensing systems in clinical environments: improving the efficiency of the patient monitoring process. 临床环境中的无线传感系统:提高患者监护过程的效率。
Pub Date : 2010-03-01 DOI: 10.1109/MEMB.2009.935713
JeongGil Ko, Tia Gao, Richard Rothman, Andreas Terzis

Multiple studies suggest that the level of patient care may decline in the future because of a larger aging population and medical staff shortages. Wireless sensing systems that automate some of the patient monitoring tasks can potentially improve the efficiency of patient workflows, but their efficacy in clinical settings is an open question. This article examines the potential of wireless sensor network (WSN) technologies to improve the efficiency of the patient-monitoring process in clinical environments. MEDiSN, a WSN designed to continuously monitor the vital signs of ambulatory patients, is designed. The usefulness of MEDiSN is validated with test bed experiments and results from a pilot study performed at the Emergency Department, Johns Hopkins Hospital. Promising results indicate that MEDiSN can tolerate high degrees of human mobility, is well received by patients and staff members, and performs well in real clinical environments.

多项研究表明,由于人口老龄化加剧和医护人员短缺,未来患者护理水平可能会下降。无线传感系统自动化了一些患者监测任务,可以潜在地提高患者工作流程的效率,但它们在临床环境中的有效性是一个悬而未决的问题。本文探讨了无线传感器网络(WSN)技术在提高临床环境中患者监测过程效率方面的潜力。设计了一种用于对流动病人生命体征进行连续监测的无线传感器网络MEDiSN。MEDiSN的有效性通过试验台实验和约翰霍普金斯医院急诊科进行的一项试点研究的结果得到了验证。令人鼓舞的结果表明,MEDiSN可以承受高度的人体活动,受到患者和工作人员的好评,并且在真实的临床环境中表现良好。
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引用次数: 71
Continuous monitoring of respiratory flow and CO(2):challenges of on-airway measurements. 连续监测呼吸流量和CO(2):气道测量的挑战。
Pub Date : 2010-03-01 DOI: 10.1109/MEMB.2009.935712
Michael B Jaffe, Joseph A Orr

In this article, the challenges of simultaneous respiratory gas concentration and flow measurements in a breathing circuit are reviewed. The tradeoffs that were considered in the development of a clinically useful on-airway combination CO(2)/flow sensor are discussed as well as the applications enabled by this on-airway combination CO(2)/flow sensor.

本文综述了呼吸回路中同时测量呼吸气体浓度和流量所面临的挑战。讨论了在开发临床有用的气道上CO(2)/流量传感器时所考虑的权衡,以及该气道上CO(2)/流量传感器所启用的应用。
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引用次数: 20
Technology transfer. 技术转让。
Pub Date : 2010-03-01 DOI: 10.1109/MEMB.2010.936452
Jesse Jayne Rutherford

Technology transfer has served the field of biomedical engineering well. Although the process is fraught with obstacles and may appear to be a distraction from more important work in the laboratory, application of technology is crucial to the furthering of the field and to public health in general. A given inventor may not want to take over the administrative tasks of protecting IP, developing a regulatory strategy, and developing a business model, and he or she does not necessarily have to; however, the inventor needs to at least know about the strategies and know there are people to turn to for leadership and guidance outside of the laboratory early in the process. And that can be all an inventor wants to do or can do: to simply turn the invention over to someone else and move on to more research in the hopes that the invention will help improve patients' health and perhaps afford the inventor and the research institution some financial reward. However, in turning an invention over completely, an inventor also loses power over how, for whom, and at what price the invention will be offered, and that is a reason to become more informed about the process, to know what you can ask for, and to stand by your invention's side in whatever capacity you are equipped to do so throughout the entire technology transfer process.

技术转移在生物医学工程领域起到了很好的作用。虽然这一过程充满障碍,而且似乎会分散人们对实验室中更重要工作的注意力,但技术的应用对该领域的进一步发展和一般公共卫生至关重要。特定的发明人可能不想接管保护知识产权、制定监管战略和开发商业模式的行政任务,他或她不一定必须这样做;然而,发明者至少需要了解策略,并且知道在这个过程的早期,在实验室之外还有人可以寻求领导和指导。这可能是发明家想做或能做的一切:简单地把发明交给别人,然后继续进行更多的研究,希望这项发明能帮助改善病人的健康,也许还能给发明者和研究机构带来一些经济回报。然而,在完全移交一项发明的过程中,发明人也失去了如何、为谁以及以什么价格提供这项发明的权力,这就是为什么要对这个过程更加了解,知道你可以要求什么,并在整个技术转让过程中以任何能力站在你的发明一边。
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引用次数: 0
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IEEE Engineering in Medicine and Biology Magazine
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