Ribosomes are essential cellular organelles made up of rRNA and rproteins found in both prokaryotic and eukaryotic cells, and play an important role in protein synthesis. The functional ribosomes are synthesized through the process called ribosome biogenesis, which proceeds with the help of certain factors such as chaperones, ribosomal proteins, and GTPases. GTPases bind to the premature ribosomal subunit and function as a checkpoint, ensuring the proper assembly of other proteins. To aid this process, GTPase undergoes conformational changes, alternating between an active GTP-bound state and an inactive GDP bound state. YsxC is a GTPase that functions this way, to help in the maturation of 50S subunit. Although YsxC plays an important role in ribosome biogenesis, a detailed knowledge of how the GDP and GTPMg2+ states of YsxC assist in the switching process is yet to be realized. Therefore, a study on the GDP and GTP-Mg2+ bound states is done for YsxC GTPase of Bacillus subtilis by all-atom molecular dynamics simulation for a period of 500 ns. The simulations aided the analysis of the RMSD from which it was noticed that both the GDP and GTP-Mg2+ states of YsxC attained equilibration after 200ns. The analysis of the Rg for the systems showed that the GTP-Mg2+ system showed higher values, in comparison to the GDP system, indicating conformational changes in the two systems. Thus, a residue-wise calculation for the difference in the SASA (solvent accessible surface area) of the GTP-Mg2+ and GDP system is done, and it is noticed that the GTP-Mg2+ system, especially in the regions recognized as Switch I and Switch II had a higher difference in SASA value. In which Switch I’s Lys55 (positive residue) and Switch II’s Arg89 (positive residue) showed a distinct difference, indicating that Switch I has more accessibility to solvent. Giving rise to a supposition that the residue Lys55 attracts the negative rRNA and aids in the binding of YsxC with the premature 50S subunit in the GTP-Mg2+ bound state by associating with the rRNA. To fathom the role of the GTP-Mg2+ bound state in increasing the SASA value of Switch I region, a community network is constructed to extract the shortest path. More number of paths are observed between the selected residue in the GTP-Mg2+ bound state inferring that the increased SASA in the Lys55 is due to the stronger connection with the nucleotide. Overall this study suggest that enhanced surface exposure of YsxC’s Sw-I in the GTP-Mg2+ bound state facilitate the GTP-Mg2+ bound system to involve in ribosome biogenesis by interacting with ribosomal constituents (rRNA and rproteins).
核糖体是由原核细胞和真核细胞中的 rRNA 和 r 蛋白组成的重要细胞器，在蛋白质合成中发挥着重要作用。功能性核糖体是通过核糖体生物发生过程合成的，这一过程在某些因素（如伴侣蛋白、核糖体蛋白和 GTP 酶）的帮助下进行。GTPase 与未成熟的核糖体亚基结合，起着检查点的作用，确保其他蛋白质的正常组装。为了帮助这一过程，GTPase 会发生构象变化，在活跃的 GTP 结合态和不活跃的 GDP 结合态之间交替。YsxC 就是这样一种 GTPase，它有助于 50S 亚基的成熟。尽管 YsxC 在核糖体生物发生过程中发挥着重要作用，但人们对 YsxC 的 GDP 和 GTPMg2+ 状态如何帮助完成切换过程的详细了解仍有待实现。因此，我们通过 500 毫微秒的全原子分子动力学模拟，对枯草芽孢杆菌 YsxC GTPase 的 GDP 和 GTP-Mg2+ 结合态进行了研究。模拟有助于分析 RMSD，从中发现 YsxC 的 GDP 和 GTP-Mg2+ 状态都在 200 ns 后达到平衡。对这两个系统的 Rg 分析表明，与 GDP 系统相比，GTP-Mg2+ 系统的 Rg 值更高，这表明这两个系统的构象发生了变化。因此，对 GTP-Mg2+ 和 GDP 系统的 SASA（溶剂可及表面积）差异进行了残基计算，结果发现，GTP-Mg2+ 系统，尤其是开关 I 和开关 II 区域的 SASA 值差异较大。其中开关 I 的 Lys55（阳性残基）和开关 II 的 Arg89（阳性残基）显示出明显的差异，表明开关 I 对溶剂的可及性更高。由此推测，残基 Lys55 可吸引阴性 rRNA，并通过与 rRNA 结合，帮助 YsxC 与处于 GTP-Mg2+ 结合态的过早 50S 亚基结合。为了弄清 GTP-Mg2+ 结合状态在增加开关 I 区域 SASA 值中的作用，我们构建了一个群落网络来提取最短路径。在 GTP-Mg2+ 结合状态下，所选残基之间有更多的路径，推断 Lys55 的 SASA 值增加是由于与核苷酸的连接更强。总之，这项研究表明，在 GTP-Mg2+ 结合状态下，YsxC 的 Sw-I 表面暴露增强，有利于 GTP-Mg2+ 结合系统通过与核糖体成分（rRNA 和 r 蛋白）相互作用参与核糖体的生物生成。
{"title":"Molecular dynamics simulation studies and dynamic network analysis of Bacillus subtilis YsxC in GDP and GTP-Mg 2+ bound states","authors":"Shuchika Devaraj Biligere, Kavya Kallahalli Mohankumar, Upendra Nagarajachari, Krishnaveni Sannathammegowda","doi":"10.34117/bjdv10n5-044","DOIUrl":"https://doi.org/10.34117/bjdv10n5-044","url":null,"abstract":"Ribosomes are essential cellular organelles made up of rRNA and rproteins found in both prokaryotic and eukaryotic cells, and play an important role in protein synthesis. The functional ribosomes are synthesized through the process called ribosome biogenesis, which proceeds with the help of certain factors such as chaperones, ribosomal proteins, and GTPases. GTPases bind to the premature ribosomal subunit and function as a checkpoint, ensuring the proper assembly of other proteins. To aid this process, GTPase undergoes conformational changes, alternating between an active GTP-bound state and an inactive GDP bound state. YsxC is a GTPase that functions this way, to help in the maturation of 50S subunit. Although YsxC plays an important role in ribosome biogenesis, a detailed knowledge of how the GDP and GTPMg2+ states of YsxC assist in the switching process is yet to be realized. Therefore, a study on the GDP and GTP-Mg2+ bound states is done for YsxC GTPase of Bacillus subtilis by all-atom molecular dynamics simulation for a period of 500 ns. The simulations aided the analysis of the RMSD from which it was noticed that both the GDP and GTP-Mg2+ states of YsxC attained equilibration after 200ns. The analysis of the Rg for the systems showed that the GTP-Mg2+ system showed higher values, in comparison to the GDP system, indicating conformational changes in the two systems. Thus, a residue-wise calculation for the difference in the SASA (solvent accessible surface area) of the GTP-Mg2+ and GDP system is done, and it is noticed that the GTP-Mg2+ system, especially in the regions recognized as Switch I and Switch II had a higher difference in SASA value. In which Switch I’s Lys55 (positive residue) and Switch II’s Arg89 (positive residue) showed a distinct difference, indicating that Switch I has more accessibility to solvent. Giving rise to a supposition that the residue Lys55 attracts the negative rRNA and aids in the binding of YsxC with the premature 50S subunit in the GTP-Mg2+ bound state by associating with the rRNA. To fathom the role of the GTP-Mg2+ bound state in increasing the SASA value of Switch I region, a community network is constructed to extract the shortest path. More number of paths are observed between the selected residue in the GTP-Mg2+ bound state inferring that the increased SASA in the Lys55 is due to the stronger connection with the nucleotide. Overall this study suggest that enhanced surface exposure of YsxC’s Sw-I in the GTP-Mg2+ bound state facilitate the GTP-Mg2+ bound system to involve in ribosome biogenesis by interacting with ribosomal constituents (rRNA and rproteins).","PeriodicalId":504671,"journal":{"name":"Brazilian Journal of Development","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140971200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The application method of Electric Submersible Pump increases the oil recovery factor Y at 05-1A block, the Nam Con Son basin, which is affected by many factors such as energy regime, fluid regime, fractures, etc. All these factors are based on the simulation model from Prosper simulation software. The process starts from the appropriate PVT data, exploitation data, selecting necessary parameters, designing wells, and predicting exploitation to find the best case for the Electric Submersible Pump exploitation plan. The results showed that if oil is only exploited by natural energy, it will not be effective, so it is possible to equip a Electric submersible pump system with 2 exploitation wells for the most efficient exploitation. The Electric Submersible Pump is applied and effective in the case of wells with high WTC and low GOR.
{"title":"Research on application of electric submersible pumps to increase oil recovery field Y, lot 05-1a, the Nam Con Son basin","authors":"Huynh Tan Tuan, Nguyen Thi Minh Thu, Pham Nguyen Duy Phuong","doi":"10.34117/bjdv10n5-042","DOIUrl":"https://doi.org/10.34117/bjdv10n5-042","url":null,"abstract":"The application method of Electric Submersible Pump increases the oil recovery factor Y at 05-1A block, the Nam Con Son basin, which is affected by many factors such as energy regime, fluid regime, fractures, etc. All these factors are based on the simulation model from Prosper simulation software. The process starts from the appropriate PVT data, exploitation data, selecting necessary parameters, designing wells, and predicting exploitation to find the best case for the Electric Submersible Pump exploitation plan. The results showed that if oil is only exploited by natural energy, it will not be effective, so it is possible to equip a Electric submersible pump system with 2 exploitation wells for the most efficient exploitation. The Electric Submersible Pump is applied and effective in the case of wells with high WTC and low GOR.","PeriodicalId":504671,"journal":{"name":"Brazilian Journal of Development","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140969409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Este trabalho tem como objetivo o projeto de controladores adaptativos para controle de posição de dois elos de um robô eletromecânico de cinco graus de liberdade (5 GDL). O controle é realizado através de simulação, usando modelos dos elos obtidos com dados reais do sistema, através de estimação de parâmetros usando o algoritmo dos mínimos quadrados recursivo (MQR). A identificação dos elos é realizada em malha aberta, utilizando dados reais coletados do robo. são projetados e implementados controladores adaptativos via imposição de pólos para o controle de posição dos dois elos. Os controladores são projetados em malha fechada com base nos modelos obtidos para os elos. a estratégia de controle a ser usada, baseia-se em um modelo explícito do sistema. Os controladores são implementados através de um programa computacional. são mostrados como resultados as curvas de saida dos modelos dos dois elos, em malha aberta e as curvas de saída dos elos sob ação dos controladores adaptativos, em malha fechada.
{"title":"Controle adaptativo usado em dois elos de um robô de cinco graus de liberdade","authors":"J. Riul, Paulo Henrique de Miranda Montenegro","doi":"10.34117/bjdv10n5-046","DOIUrl":"https://doi.org/10.34117/bjdv10n5-046","url":null,"abstract":"Este trabalho tem como objetivo o projeto de controladores adaptativos para controle de posição de dois elos de um robô eletromecânico de cinco graus de liberdade (5 GDL). O controle é realizado através de simulação, usando modelos dos elos obtidos com dados reais do sistema, através de estimação de parâmetros usando o algoritmo dos mínimos quadrados recursivo (MQR). A identificação dos elos é realizada em malha aberta, utilizando dados reais coletados do robo. são projetados e implementados controladores adaptativos via imposição de pólos para o controle de posição dos dois elos. Os controladores são projetados em malha fechada com base nos modelos obtidos para os elos. a estratégia de controle a ser usada, baseia-se em um modelo explícito do sistema. Os controladores são implementados através de um programa computacional. são mostrados como resultados as curvas de saida dos modelos dos dois elos, em malha aberta e as curvas de saída dos elos sob ação dos controladores adaptativos, em malha fechada.","PeriodicalId":504671,"journal":{"name":"Brazilian Journal of Development","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140970326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Este estudo tem como objetivo analisar o impacto das tecnologias emergentes na gestão de conflitos e eventos críticos na área de segurança pública, investigando suas potenciais vantagens e desafios. A metodologia utilizada permite classificar a pesquisa como exploratória, com o uso de levantamento bibliográfico para coleta dos dados. A abordagem do problema é qualitativa, e a análise dos dados é crítica de conteúdo. A pesquisa identificou um amplo espectro de tecnologias emergentes relevantes para a segurança pública, incluindo Inteligência Artificial, Internet das Coisas, análise de big data e automação. Essas tecnologias têm o potencial de aprimorar a prevenção, resposta e recuperação de conflitos e eventos críticos, oferecendo soluções inovadoras para as autoridades de segurança. No entanto, a implementação dessas tecnologias também traz desafios éticos, legais e práticos, como questões de privacidade, discriminação algorítmica e segurança de dados. Este estudo permitiu uma análise aprofundada das tecnologias emergentes na segurança pública. Concluiu-se que essas tecnologias oferecem oportunidades significativas para melhorar a eficácia das operações de segurança pública. No entanto, é fundamental abordar os desafios de forma responsável, com regulamentações adequadas, transparência e supervisão. O uso ético e eficaz das tecnologias emergentes na segurança pública é essencial para a promoção de uma sociedade mais segura e resiliente.
{"title":"A utilização de tecnologias inovadoras na otimização das operações policiais: impactos e desafios para Polícia Militar","authors":"Sabrina Vettorazzi Nagata","doi":"10.34117/bjdv10n5-039","DOIUrl":"https://doi.org/10.34117/bjdv10n5-039","url":null,"abstract":"Este estudo tem como objetivo analisar o impacto das tecnologias emergentes na gestão de conflitos e eventos críticos na área de segurança pública, investigando suas potenciais vantagens e desafios. A metodologia utilizada permite classificar a pesquisa como exploratória, com o uso de levantamento bibliográfico para coleta dos dados. A abordagem do problema é qualitativa, e a análise dos dados é crítica de conteúdo. A pesquisa identificou um amplo espectro de tecnologias emergentes relevantes para a segurança pública, incluindo Inteligência Artificial, Internet das Coisas, análise de big data e automação. Essas tecnologias têm o potencial de aprimorar a prevenção, resposta e recuperação de conflitos e eventos críticos, oferecendo soluções inovadoras para as autoridades de segurança. No entanto, a implementação dessas tecnologias também traz desafios éticos, legais e práticos, como questões de privacidade, discriminação algorítmica e segurança de dados. Este estudo permitiu uma análise aprofundada das tecnologias emergentes na segurança pública. Concluiu-se que essas tecnologias oferecem oportunidades significativas para melhorar a eficácia das operações de segurança pública. No entanto, é fundamental abordar os desafios de forma responsável, com regulamentações adequadas, transparência e supervisão. O uso ético e eficaz das tecnologias emergentes na segurança pública é essencial para a promoção de uma sociedade mais segura e resiliente.","PeriodicalId":504671,"journal":{"name":"Brazilian Journal of Development","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140971918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Back ground: The study focussed on the teaching community of Sri Lanka which examined, sense of efficacy, stress, years in service and resilience. Aims: There were two objectives in the study. First objective was to examine whether there was a relationship between a teacher’s sense of efficacy and the perceived occupational stress. Second objective was to understand whether a teacher’s years in service had an impact on their resilience. Method: A questionnaire with few demographic questions and three scales which assessed their sense of efficacy, occupational stress and resilience were presented via Qualitrics. Participants were attracted through a social media advert. Approval was granted to conduct the study under reference number UG7496 by the ethics panel of Cardiff School of Sport and Health Sciences. A quantitative research was conducted and the collected data was analysed using SPSS. Results: A total number of 113 responses were collected where 89 responses were used for analysis. Spearman’s correlation tests were carried out, and the computed results indicated a moderate negative relationship between teacher’s sense of efficacy and occupational stress, r=-0.56, n=89, p<.001. Further, a strong positive relationship was indicated between years in service and resilience of a teacher, r=0.70, n=89, p<.001. Conclusions: Both hypotheses which were tested were supported by the obtained results. Therefore, it was suggested that teachers with greater sense of efficacy perceived less occupational tress and teachers with more work experience had higher levels of resilience.
{"title":"The influence of self-efficacy and experience of Sri Lankan teachers on their experience of occupational stress and resilience","authors":"Milinda Jayalath","doi":"10.34117/bjdv10n5-040","DOIUrl":"https://doi.org/10.34117/bjdv10n5-040","url":null,"abstract":"Back ground: The study focussed on the teaching community of Sri Lanka which examined, sense of efficacy, stress, years in service and resilience. Aims: There were two objectives in the study. First objective was to examine whether there was a relationship between a teacher’s sense of efficacy and the perceived occupational stress. Second objective was to understand whether a teacher’s years in service had an impact on their resilience. Method: A questionnaire with few demographic questions and three scales which assessed their sense of efficacy, occupational stress and resilience were presented via Qualitrics. Participants were attracted through a social media advert. Approval was granted to conduct the study under reference number UG7496 by the ethics panel of Cardiff School of Sport and Health Sciences. A quantitative research was conducted and the collected data was analysed using SPSS. Results: A total number of 113 responses were collected where 89 responses were used for analysis. Spearman’s correlation tests were carried out, and the computed results indicated a moderate negative relationship between teacher’s sense of efficacy and occupational stress, r=-0.56, n=89, p<.001. Further, a strong positive relationship was indicated between years in service and resilience of a teacher, r=0.70, n=89, p<.001. Conclusions: Both hypotheses which were tested were supported by the obtained results. Therefore, it was suggested that teachers with greater sense of efficacy perceived less occupational tress and teachers with more work experience had higher levels of resilience.","PeriodicalId":504671,"journal":{"name":"Brazilian Journal of Development","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140976302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Este artigo tem o objetivo de demonstrar a importância da qualificação e da capacitação dos policiais militares que conduzem viaturas da Corporação, através de ensinamentos teóricos e práticos, assim, atendendo as normas vigentes que apontam requisitos para autorizar que determinado motorista conduza um veículo de emergência. O Conselho Nacional de Trânsito autoriza que órgãos da segurança pública ministrem o curso especializado de condutor de veículo de emergência para seus efetivos, ressaltando que empresas privadas ofereçam o curso, mas com certeza sem a expertise das peculiaridades atinentes ao serviço policial, ao patrulhamento ostensivo motorizado, que envolve muito mais conhecimento e decisões rápidas que simplesmente dirigir. O rol de disciplinas regulamentares e obrigatórias são semelhantes as aplicadas nos cursos de formação de policiais, o que facilita a compreensão em paralelo com as práticas de direção em situação de risco citada como obrigatória na legislação de trânsito. Entendimentos jurídicos que o policial militar que se envolve em sinistro de trânsito na condução de uma viatura policial está amparado pela excludente de ilicitude do estrito cumprimento do dever legal, assim livre de arcar com custos de ressarcimentos. Devido a este fato, a manutenção do treinamento dos condutores de viaturas policiais se mostra como um ponto primordial para que suas ações não venham a ser imprecisas com culpa comprovada.
{"title":"Curso de condutor de veículo de emergência aplicado a atividade Policial Militar","authors":"Marcel Rocha","doi":"10.34117/bjdv10n5-037","DOIUrl":"https://doi.org/10.34117/bjdv10n5-037","url":null,"abstract":"Este artigo tem o objetivo de demonstrar a importância da qualificação e da capacitação dos policiais militares que conduzem viaturas da Corporação, através de ensinamentos teóricos e práticos, assim, atendendo as normas vigentes que apontam requisitos para autorizar que determinado motorista conduza um veículo de emergência. O Conselho Nacional de Trânsito autoriza que órgãos da segurança pública ministrem o curso especializado de condutor de veículo de emergência para seus efetivos, ressaltando que empresas privadas ofereçam o curso, mas com certeza sem a expertise das peculiaridades atinentes ao serviço policial, ao patrulhamento ostensivo motorizado, que envolve muito mais conhecimento e decisões rápidas que simplesmente dirigir. O rol de disciplinas regulamentares e obrigatórias são semelhantes as aplicadas nos cursos de formação de policiais, o que facilita a compreensão em paralelo com as práticas de direção em situação de risco citada como obrigatória na legislação de trânsito. Entendimentos jurídicos que o policial militar que se envolve em sinistro de trânsito na condução de uma viatura policial está amparado pela excludente de ilicitude do estrito cumprimento do dever legal, assim livre de arcar com custos de ressarcimentos. Devido a este fato, a manutenção do treinamento dos condutores de viaturas policiais se mostra como um ponto primordial para que suas ações não venham a ser imprecisas com culpa comprovada.","PeriodicalId":504671,"journal":{"name":"Brazilian Journal of Development","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140983899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O principal objectivo do presente estudo foi o de fazer uma revisão-síntese da literatura relacionada com os impactos económicos da blockchain. Neste sentido foi utilizada a técnica de análise documental, aplicada a revisão da literatura relevante sobre a tecnologia blockchain e os seus principais impactos económicos. Por via da revisão bibliográfica realizada, foi possível chegar-se a três resultados principais: que as áreas do conhecimento que mais têm pesquisado sobre o tema são as de finanças e economia; que o maior impacto económico da tecnologia blockchain deriva da sua aplicação no sector financeiro, a partir da criação da primeira moeda digital a bitcoin, tornando o comercio electrónico e as operações financeiras mais rápidas, seguras e a menor custo marginal, ou seja, mais eficientes e finalmente que dado o seu caracter altamente desrruptivo a tecnologia blockchain está a alterar o modelo de negócio das empresas.
{"title":"Impactos económicos da blockchain: uma revisão síntese da literatura","authors":"Luzolo Domingos Sanches-António","doi":"10.34117/bjdv10n5-035","DOIUrl":"https://doi.org/10.34117/bjdv10n5-035","url":null,"abstract":"O principal objectivo do presente estudo foi o de fazer uma revisão-síntese da literatura relacionada com os impactos económicos da blockchain. Neste sentido foi utilizada a técnica de análise documental, aplicada a revisão da literatura relevante sobre a tecnologia blockchain e os seus principais impactos económicos. Por via da revisão bibliográfica realizada, foi possível chegar-se a três resultados principais: que as áreas do conhecimento que mais têm pesquisado sobre o tema são as de finanças e economia; que o maior impacto económico da tecnologia blockchain deriva da sua aplicação no sector financeiro, a partir da criação da primeira moeda digital a bitcoin, tornando o comercio electrónico e as operações financeiras mais rápidas, seguras e a menor custo marginal, ou seja, mais eficientes e finalmente que dado o seu caracter altamente desrruptivo a tecnologia blockchain está a alterar o modelo de negócio das empresas.","PeriodicalId":504671,"journal":{"name":"Brazilian Journal of Development","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140983338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Prashant Tripathi, Shivanshu Rathaur, Jyoti Antil, A. Kanaujia, Sanjive Shukla
Of the three extant amphibian orders, Anurans commonly known as frogs and toads are by far the most specious, diversified, and ubiquitous. Anurans are one of the most endangered groups of creatures on earth and perform a critical function in the ecology. The preservation of biodiversity, sustainable development and food security are all major goals of agroforestry. In dispersed agricultural environments, agricultural activities like paddy and rice fields may offer frogs a habitat and aid in their preservation. The long-term impacts of introducing frogs in rice yield and soil Phosphorus availability are largely underestimated and undervalued. Currently, the cultivation of rice paddy creates 11% of the anthropogenic CH4 (Methane) in the atmosphere, which can be regulated through the use of frogs. The frogs and toads are the bio-indicators of the environment. They consume bugs, weeds, and other harmful insects to keep their numbers in check. They also operate as a biological pest management and supply food for other creatures including birds, reptiles, and small mammals. The frog's waste increases the rice crops' access to nutrients and also has a fertilising effect. However, excessive pesticide usage and public ignorance about these species are causing the anuran population to decline rapidly.
{"title":"Anurans and their contribution to agriculture: a review","authors":"Prashant Tripathi, Shivanshu Rathaur, Jyoti Antil, A. Kanaujia, Sanjive Shukla","doi":"10.34117/bjdv10n5-036","DOIUrl":"https://doi.org/10.34117/bjdv10n5-036","url":null,"abstract":"Of the three extant amphibian orders, Anurans commonly known as frogs and toads are by far the most specious, diversified, and ubiquitous. Anurans are one of the most endangered groups of creatures on earth and perform a critical function in the ecology. The preservation of biodiversity, sustainable development and food security are all major goals of agroforestry. In dispersed agricultural environments, agricultural activities like paddy and rice fields may offer frogs a habitat and aid in their preservation. The long-term impacts of introducing frogs in rice yield and soil Phosphorus availability are largely underestimated and undervalued. Currently, the cultivation of rice paddy creates 11% of the anthropogenic CH4 (Methane) in the atmosphere, which can be regulated through the use of frogs. The frogs and toads are the bio-indicators of the environment. They consume bugs, weeds, and other harmful insects to keep their numbers in check. They also operate as a biological pest management and supply food for other creatures including birds, reptiles, and small mammals. The frog's waste increases the rice crops' access to nutrients and also has a fertilising effect. However, excessive pesticide usage and public ignorance about these species are causing the anuran population to decline rapidly.","PeriodicalId":504671,"journal":{"name":"Brazilian Journal of Development","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140985389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mahara Hetti Arachchige Deepika Subhashini, Chandrika Malkanthi Nanayakkara, D. M. J. Senanayake
Aglaonema ‘Maria’ is one of the key foliage plants that has gained high demand in foreign destinations in the last few years. This study was conducted to characterize Bacillus velezensis DCJ 2, assess its plant growth promotion effect and investigate the effectiveness of different delivery methods of the bacterial inoculum for the growth promotion of Aglaonema ‘Maria’. In this context, DCJ 2, isolated from the rhizosphere soil of A. Maria was screened to investigate its potential as a plant growth-promoting bacterium. The pure culture of DCJ 2 maintained on nutrient agar was utilized for morphological, biochemical and physiological examinations. The molecular characterization of the strain was performed with different primer pairs targeting 16SrRNA, gyrA, pgsB and sugar kinase genes of DCJ 2. A pot experiment was carried out to investigate the plant growth promotion effect. It was conducted in the greenhouse as per the complete randomized block design with eight treatments and five replicates. . Healthy plants of A. ‘Maria’ established in field soil and solarized soil were treated with 100 ml of the suspension of the DCJ 2 at the rate of 10 8 CFU/ml either as a soil drench or foliar spray. The partial 16SrRNA, gyrA, pgsB and sugar kinase gene sequences of DCJ 2, BLAST searched in the NCBI database revealed that it has a high similarity to Bacillus velezensis. The pot experiment showed that the application of strain DCJ 2 as a soil drench to solarized soil (Treatment 6) yielded a significant increase in growth parameters at p=0.05. Based on molecular analysis, morphological, biochemical, and physiological reactions, DCJ 2 was identified as Bacillus velezensis. This study revealed that B. velezensis DCJ 2 has the potential to boost the growth of A. Maria and hence serve as a base for developing a biofertilizer.
{"title":"Characterization of Bacillus velezensis DCJ 2 isolated from the rhizosphere soil of aglaonema ‘Maria’ and investigation of its plant growth-promoting effects","authors":"Mahara Hetti Arachchige Deepika Subhashini, Chandrika Malkanthi Nanayakkara, D. M. J. Senanayake","doi":"10.34117/bjdv10n5-038","DOIUrl":"https://doi.org/10.34117/bjdv10n5-038","url":null,"abstract":"Aglaonema ‘Maria’ is one of the key foliage plants that has gained high demand in foreign destinations in the last few years. This study was conducted to characterize Bacillus velezensis DCJ 2, assess its plant growth promotion effect and investigate the effectiveness of different delivery methods of the bacterial inoculum for the growth promotion of Aglaonema ‘Maria’. In this context, DCJ 2, isolated from the rhizosphere soil of A. Maria was screened to investigate its potential as a plant growth-promoting bacterium. The pure culture of DCJ 2 maintained on nutrient agar was utilized for morphological, biochemical and physiological examinations. The molecular characterization of the strain was performed with different primer pairs targeting 16SrRNA, gyrA, pgsB and sugar kinase genes of DCJ 2. A pot experiment was carried out to investigate the plant growth promotion effect. It was conducted in the greenhouse as per the complete randomized block design with eight treatments and five replicates. . Healthy plants of A. ‘Maria’ established in field soil and solarized soil were treated with 100 ml of the suspension of the DCJ 2 at the rate of 10 8 CFU/ml either as a soil drench or foliar spray. The partial 16SrRNA, gyrA, pgsB and sugar kinase gene sequences of DCJ 2, BLAST searched in the NCBI database revealed that it has a high similarity to Bacillus velezensis. The pot experiment showed that the application of strain DCJ 2 as a soil drench to solarized soil (Treatment 6) yielded a significant increase in growth parameters at p=0.05. Based on molecular analysis, morphological, biochemical, and physiological reactions, DCJ 2 was identified as Bacillus velezensis. This study revealed that B. velezensis DCJ 2 has the potential to boost the growth of A. Maria and hence serve as a base for developing a biofertilizer.","PeriodicalId":504671,"journal":{"name":"Brazilian Journal of Development","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140985423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Glocalization is a “simultaneity—the co-presence—of both universalizing and particularizing tendencies” emphasizing the need for tempering the effects of local conditions on global pressures. While the increasing presence of best-known fast food chain restaurants worldwide such as McDonald’s and KFC is a manifestation of globalization, the shrewd and strategic adaptations of their menu to satiate the local palates and tastes by these “Glocal Enterprises” is illustrative of glocalization. Conversely, the chief point of glocalization perspective is: “even the most local ways of carrying out business operations are more and more co-constituted by economic and social trends that are most global.” Language has a huge role to play in addressing the cultural and linguistic barriers and designing a successful global talent management and language learning solution that is complemented by local support. When used as an extension of the “Think Global, Act Local” grassroots movement, glocalization also refers to market advantage of local businesses versus global companies. In the face of globalization, both the little guys and would-be entrepreneurs can emerge triumphant by tapping into their hometown markets and then scaling up. However, it is imperative that MNCs restructure the national economies to become and remain more resilient, sustainable, and inclusive in their globalization to glocalization migration odyssey. An attempt would be made in this conceptual Paper to address this issue—a challenge and an opportunity—for the key players by enumerating the stories of successful transition into glocalization by several popular Multi National Corporations in the Indian context.
{"title":"Glocalization: an analysis into it’s conceptual and strategic underpinnings","authors":"Suryanarayana Alamuri, Ravi Aluvala","doi":"10.34117/bjdv10n5-031","DOIUrl":"https://doi.org/10.34117/bjdv10n5-031","url":null,"abstract":"Glocalization is a “simultaneity—the co-presence—of both universalizing and particularizing tendencies” emphasizing the need for tempering the effects of local conditions on global pressures. While the increasing presence of best-known fast food chain restaurants worldwide such as McDonald’s and KFC is a manifestation of globalization, the shrewd and strategic adaptations of their menu to satiate the local palates and tastes by these “Glocal Enterprises” is illustrative of glocalization. Conversely, the chief point of glocalization perspective is: “even the most local ways of carrying out business operations are more and more co-constituted by economic and social trends that are most global.” Language has a huge role to play in addressing the cultural and linguistic barriers and designing a successful global talent management and language learning solution that is complemented by local support. When used as an extension of the “Think Global, Act Local” grassroots movement, glocalization also refers to market advantage of local businesses versus global companies. In the face of globalization, both the little guys and would-be entrepreneurs can emerge triumphant by tapping into their hometown markets and then scaling up. However, it is imperative that MNCs restructure the national economies to become and remain more resilient, sustainable, and inclusive in their globalization to glocalization migration odyssey. An attempt would be made in this conceptual Paper to address this issue—a challenge and an opportunity—for the key players by enumerating the stories of successful transition into glocalization by several popular Multi National Corporations in the Indian context.","PeriodicalId":504671,"journal":{"name":"Brazilian Journal of Development","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140993114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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