Before becoming a first-class urban area, the administrative, economic, cultural, and educational center of Binh Duong province, Thu Dau Mot was considered the "capital" of the Southeast region in many historical periods. This geographical location has brought together many important resources for the socio-economic development of the locality and the region. This article analyzes two development resources of Thu Dau Mot: natural resources (geographical location - the central hub of the Southeast region) and social resources (people in terms of harmonious relationships in the development of a region). From analyzing these two resources, the article discusses issues that need attention in building strategic directions to ensure Thu Dau Mot city continues to uphold its central position in the Southeast region, integrating the city regionally and internationally in terms of economy, society, and culture.
Thu Dau Mot 在成为平阳省行政、经济、文化和教育中心的一流城区之前，在许多历史时期曾被视为东南地区的 "首都"。这一地理位置汇集了许多重要资源，促进了当地和整个地区的社会经济发展。本文对秋道莫的两种发展资源进行了分析：自然资源（地理位置--东南地区的中心枢纽）和社会资源（地区发展中和谐关系的人文因素）。通过对这两种资源的分析，文章讨论了在制定战略方向时需要注意的问题，以确保 Thu Dau Mot 市继续保持其在东南地区的中心地位，并在经济、社会和文化方面实现区域和国际一体化。
{"title":"Assessment of geographical location and population characteristics of Thu Dau Mot city in the past and presente","authors":"Pham Văn Thinh","doi":"10.34117/bjdv10n6-009","DOIUrl":"https://doi.org/10.34117/bjdv10n6-009","url":null,"abstract":"Before becoming a first-class urban area, the administrative, economic, cultural, and educational center of Binh Duong province, Thu Dau Mot was considered the \"capital\" of the Southeast region in many historical periods. This geographical location has brought together many important resources for the socio-economic development of the locality and the region. This article analyzes two development resources of Thu Dau Mot: natural resources (geographical location - the central hub of the Southeast region) and social resources (people in terms of harmonious relationships in the development of a region). From analyzing these two resources, the article discusses issues that need attention in building strategic directions to ensure Thu Dau Mot city continues to uphold its central position in the Southeast region, integrating the city regionally and internationally in terms of economy, society, and culture.","PeriodicalId":504671,"journal":{"name":"Brazilian Journal of Development","volume":"42 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141385738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
As microexpressões são movimentos faciais que ocorrem quando o indivíduo se emociona, exclusivas para cada uma das sete emoções primárias, felicidade, tristeza, raiva, medo, surpresa, nojo e desprezo. Este estudo desenvolveu-se com o objetivo de investigar a possibilidade de se verificar as microexpressões faciais em alunos de psicologia da Universidade Estadual Paulista de Assis se igualam aos estudos de Paul Ekman, hipótese esta que pode ser comprovada ao final do estudo, pois os participantes do estudo apresentaram microexpressões faciais assim como proposto pelos estudos do Paul Ekman quando expostos à imagens geradoras dessas microexpressões.
{"title":"A utilização da detecção das microexpressões faciais no setting terapêutico: estudos introdutórios","authors":"Miguel Degani Ottaiano, Cláudio Edward dos Reis","doi":"10.34117/bjdv10n6-015","DOIUrl":"https://doi.org/10.34117/bjdv10n6-015","url":null,"abstract":"As microexpressões são movimentos faciais que ocorrem quando o indivíduo se emociona, exclusivas para cada uma das sete emoções primárias, felicidade, tristeza, raiva, medo, surpresa, nojo e desprezo. Este estudo desenvolveu-se com o objetivo de investigar a possibilidade de se verificar as microexpressões faciais em alunos de psicologia da Universidade Estadual Paulista de Assis se igualam aos estudos de Paul Ekman, hipótese esta que pode ser comprovada ao final do estudo, pois os participantes do estudo apresentaram microexpressões faciais assim como proposto pelos estudos do Paul Ekman quando expostos à imagens geradoras dessas microexpressões.","PeriodicalId":504671,"journal":{"name":"Brazilian Journal of Development","volume":"60 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141385406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Shirsath, Milind C Nagare, Kuldeep T Padhyar, Avinash U. Nerkar, Gokul V Suryawanshi, Tulsidas S Savale
Ionic liquids (ILs) are liquid organic salts owning a lot of interesting properties that rapid increase various research to study their utilization in numerous fields. The enormous utilization and scope of ILs in a diversity of fields have been presented based upon available literature. ILs were firstly addressed as a green alternative to traditional solvents because of their almost non-existent vapor pressure as environmental replacement of most common volatile solvents in industrial processes for their damaging effects on the environment. Systematic and brief investigation of the several IL applications has been done highlighting some recent significant advances in every zone. This review will contribute to helpful the significant knowledge of all branch of research based on ILs. Apart from this, the tasks associated with the industrial use of ILs have been discussed, which require further investigation.
离子液体（ILs）是一种液态有机盐，具有许多有趣的特性，因此各种研究对其在众多领域的应用研究迅速增加。根据现有文献，离子液体在多个领域都有广泛的应用。惰性溶胶首先被视为传统溶剂的绿色替代品，因为它们几乎不存在蒸气压，可以替代工业过程中对环境造成破坏的最常见挥发性溶剂。我们对几种惰性溶剂的应用进行了系统而简要的研究，重点介绍了最近在各个领域取得的一些重大进展。这篇综述将有助于了解所有基于 IL 的研究分支的重要知识。此外，还讨论了与工业使用 IL 有关的任务，这些任务需要进一步研究。
{"title":"Ionic liquids: green organic transformation with dual solvent-catalyst strategy and its multidisciplinary applications","authors":"N. Shirsath, Milind C Nagare, Kuldeep T Padhyar, Avinash U. Nerkar, Gokul V Suryawanshi, Tulsidas S Savale","doi":"10.34117/bjdv10n6-012","DOIUrl":"https://doi.org/10.34117/bjdv10n6-012","url":null,"abstract":"Ionic liquids (ILs) are liquid organic salts owning a lot of interesting properties that rapid increase various research to study their utilization in numerous fields. The enormous utilization and scope of ILs in a diversity of fields have been presented based upon available literature. ILs were firstly addressed as a green alternative to traditional solvents because of their almost non-existent vapor pressure as environmental replacement of most common volatile solvents in industrial processes for their damaging effects on the environment. Systematic and brief investigation of the several IL applications has been done highlighting some recent significant advances in every zone. This review will contribute to helpful the significant knowledge of all branch of research based on ILs. Apart from this, the tasks associated with the industrial use of ILs have been discussed, which require further investigation.","PeriodicalId":504671,"journal":{"name":"Brazilian Journal of Development","volume":"6 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141384795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Impact of climate change on growth and yield of wheat, through various Representative Concentration Pathways (RCPs) in various agro-climatic zones of India, by using CERES-wheat model of DSSAT version 4.6 (Hoogenboom et al., 2023). Main purpose of the present study was to judge the performance of DSSAT model for wheat crop grown under diverse production environments of Bihar, India. Seven wheat cultivars (PBW 343, Ludhiana, Meerut, Faizabad & Kanpur), (WH711, Ambala), (Raj 3765, Jaipur), (LOK 1, Bhopal & Indore), (Malviya 234, Varanasi); (HD 2824, Samstipur) and (HD 2733, Bhagalpur), with six sowing dates (25th October, 1st November, 8th November, 15th November, 22nd November and 29th November) using historic daily weather datasets from 1985-2015 and with decadal 2020 to 2100 (RCPs) for use in running of the CERES-wheat model, to evaluate the impact of temperature rise and carbon dioxide concentration increase by using future climate change scenarios. Test locations chosen for the study were contrasting during growing period of wheat crop. Effect of sowing date on wheat on yield of wheat was significantly different, in a way to identify the optimal date of sowing under normal climatic condition as well depended on the extent of temperature rise scenarios. The optimal date of sowing differed among locations in various agro-climatic zones. In north-west locations of India (specifically in Punjab) showed increased yield through one degree celcius temperature rise, due to cooler environment during the pre-anthesis phase, whereas the yield decreased with increased temperature due to reduction in crop growing duration. But interation of temperature and CO2 was quite evident. In central part of India, say in Madhya Pradesh the effect of temperature rise resulted in decreased yield due to significant reduction in duration of the crop, as in Central India usually the temperatures are relatively higher compared to north Alluvial Plains. Choice of cultivar matching the climate condition coupled with the climate change scenario was successfully chosen through use of CERES-Wheat model. The paper clearly demonstrated the potential in use of DSSAT (CERES-Wheat) model in simulating the yield of wheat crop grown under diverse production environment, varying climatic condition and aiding in choice of suitable cultivats for sustained agri-production.
{"title":"Simulating impact of climate change on growth and yield of wheat crop grown in various agro-climatic zones of India by using CERES-Wheat (DSSAT v 4.6)","authors":"Pankaj Kumar Singh, Shri Abhiram G Sankar, Shri Sanjay Kumar Agarwal, Ravi Shankar Singh, Kamlesh Kumar Singh, Akhilesh Gupta, Naveen Kalra","doi":"10.34117/bjdv10n6-013","DOIUrl":"https://doi.org/10.34117/bjdv10n6-013","url":null,"abstract":"Impact of climate change on growth and yield of wheat, through various Representative Concentration Pathways (RCPs) in various agro-climatic zones of India, by using CERES-wheat model of DSSAT version 4.6 (Hoogenboom et al., 2023). Main purpose of the present study was to judge the performance of DSSAT model for wheat crop grown under diverse production environments of Bihar, India. Seven wheat cultivars (PBW 343, Ludhiana, Meerut, Faizabad & Kanpur), (WH711, Ambala), (Raj 3765, Jaipur), (LOK 1, Bhopal & Indore), (Malviya 234, Varanasi); (HD 2824, Samstipur) and (HD 2733, Bhagalpur), with six sowing dates (25th October, 1st November, 8th November, 15th November, 22nd November and 29th November) using historic daily weather datasets from 1985-2015 and with decadal 2020 to 2100 (RCPs) for use in running of the CERES-wheat model, to evaluate the impact of temperature rise and carbon dioxide concentration increase by using future climate change scenarios. Test locations chosen for the study were contrasting during growing period of wheat crop. Effect of sowing date on wheat on yield of wheat was significantly different, in a way to identify the optimal date of sowing under normal climatic condition as well depended on the extent of temperature rise scenarios. The optimal date of sowing differed among locations in various agro-climatic zones. In north-west locations of India (specifically in Punjab) showed increased yield through one degree celcius temperature rise, due to cooler environment during the pre-anthesis phase, whereas the yield decreased with increased temperature due to reduction in crop growing duration. But interation of temperature and CO2 was quite evident. In central part of India, say in Madhya Pradesh the effect of temperature rise resulted in decreased yield due to significant reduction in duration of the crop, as in Central India usually the temperatures are relatively higher compared to north Alluvial Plains. Choice of cultivar matching the climate condition coupled with the climate change scenario was successfully chosen through use of CERES-Wheat model. The paper clearly demonstrated the potential in use of DSSAT (CERES-Wheat) model in simulating the yield of wheat crop grown under diverse production environment, varying climatic condition and aiding in choice of suitable cultivats for sustained agri-production.","PeriodicalId":504671,"journal":{"name":"Brazilian Journal of Development","volume":"19 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141383209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. B. Peixoto, Giovani Brandão Mafra de Carvalho, Ernesto Acosta Martínez, J. A. Bispo
The combined effect of urea and high pressure on bovine serum albumin (BSA) under denaturing conditions was analyzed using a thermodynamic approach involving a two-state transition and numerical modelling. There was no significant denaturation at pU (-log [Urea]) values lower than -0.7 and pressure up to 100 MPa, with a Gibbs free energy deltaGp,pu > 1116 J/mol. At higher pressure and urea concentration the process of denaturation became more spontaneous, with deltaGp,pu reaching about ‑14000 J/mol at pU = -0.9030 and 250 MPa. Analysis of the volume change of denaturation (deltaV) and the stoichiometric coefficient of urea uptake (miU) revealed the occurrence of heterogeneous protein structures during denaturation with a maximum (deltaV) value of -160 mL/mol and miU = 16.15 mol U/mol BSA at pU = -0.825 at 248 MPa. Intermediate pressure values and urea concentrations resulted in an apparent structural homogenization of the albumin in solution. These results suggest that the physicochemical treatments used here can provide a useful experimental approach for describing the processes involved in protein folding/unfolding.
{"title":"Urea potentiates the denaturation of bovine serum albumin induced by high hydrostatic pressure","authors":"A. B. Peixoto, Giovani Brandão Mafra de Carvalho, Ernesto Acosta Martínez, J. A. Bispo","doi":"10.34117/bjdv10n6-014","DOIUrl":"https://doi.org/10.34117/bjdv10n6-014","url":null,"abstract":"The combined effect of urea and high pressure on bovine serum albumin (BSA) under denaturing conditions was analyzed using a thermodynamic approach involving a two-state transition and numerical modelling. There was no significant denaturation at pU (-log [Urea]) values lower than -0.7 and pressure up to 100 MPa, with a Gibbs free energy deltaGp,pu > 1116 J/mol. At higher pressure and urea concentration the process of denaturation became more spontaneous, with deltaGp,pu reaching about ‑14000 J/mol at pU = -0.9030 and 250 MPa. Analysis of the volume change of denaturation (deltaV) and the stoichiometric coefficient of urea uptake (miU) revealed the occurrence of heterogeneous protein structures during denaturation with a maximum (deltaV) value of -160 mL/mol and miU = 16.15 mol U/mol BSA at pU = -0.825 at 248 MPa. Intermediate pressure values and urea concentrations resulted in an apparent structural homogenization of the albumin in solution. These results suggest that the physicochemical treatments used here can provide a useful experimental approach for describing the processes involved in protein folding/unfolding.","PeriodicalId":504671,"journal":{"name":"Brazilian Journal of Development","volume":"54 S6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141385511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The study aimed to investigate how leader behaviors, institutional factors, Coach attributes, and Coach Experience contributed to the team performance of national-level women's teams in Sri Lanka. The population consisted of one hundred and ten (N=110) female athletes who participated in team sports at the national level in Sri Lanka. The research employed a quantitative approach, distributing questionnaires to players of Sri Lanka's national-level women's teams. It utilized a census sampling technique, resulting in a sample size of 110 participants. Statistical analysis was conducted using the Statistical Package for Social Sciences (SPSS) Version 23. The study hypothesized that leadership behaviors, institutional factors, coach attributes, and coach experience significantly impacted team performance. Results revealed a significant positive impact of democratic leadership, coach attributes, coach experience, and institutional factors on team performance, while autocratic leadership demonstrated a significant negative impact. Coaches, team managers, and sports administrators could utilize the findings to identify essential elements for the success of Sri Lankan women's national teams.
{"title":"Examining leader behaviors and institutional factors influencing the performance of women's national teams in Sri Lanka: an empirical investigation","authors":"Weerappulige Shohani Madurangani Fernando, Hettiarachchige Piumi Navamali Perera, Madara Hansamali Kumaragamage","doi":"10.34117/bjdv10n6-010","DOIUrl":"https://doi.org/10.34117/bjdv10n6-010","url":null,"abstract":"The study aimed to investigate how leader behaviors, institutional factors, Coach attributes, and Coach Experience contributed to the team performance of national-level women's teams in Sri Lanka. The population consisted of one hundred and ten (N=110) female athletes who participated in team sports at the national level in Sri Lanka. The research employed a quantitative approach, distributing questionnaires to players of Sri Lanka's national-level women's teams. It utilized a census sampling technique, resulting in a sample size of 110 participants. Statistical analysis was conducted using the Statistical Package for Social Sciences (SPSS) Version 23. The study hypothesized that leadership behaviors, institutional factors, coach attributes, and coach experience significantly impacted team performance. Results revealed a significant positive impact of democratic leadership, coach attributes, coach experience, and institutional factors on team performance, while autocratic leadership demonstrated a significant negative impact. Coaches, team managers, and sports administrators could utilize the findings to identify essential elements for the success of Sri Lankan women's national teams.","PeriodicalId":504671,"journal":{"name":"Brazilian Journal of Development","volume":"46 47","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141384326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O artigo apresenta uma metodologia multifacetada que integra revisão bibliográfica e a proposição de diretrizes para melhorar a resposta em acidentes com múltiplas vítimas em áreas urbanas de tráfego intenso. Iniciando com uma revisão abrangente da literatura sobre atendimento pré-hospitalar (APH), triagem, controle de tráfego e escolta policial para ambulâncias, o estudo baseou-se em normas técnicas e acadêmicas para fundamentar suas propostas. A partir dessas informações, foram propostas o estabelecimento de diretrizes específicas para a integração entre a Polícia Militar e o Corpo de Bombeiros do Paraná, incluindo Procedimentos Operacionais Padrão (POPs) para treinamento conjunto, triagem de vítimas, controle de tráfego e escolta de ambulâncias. A triagem, destacada pelo método START, é essencial para priorizar vítimas em situações de recursos limitados, garantindo que os cuidados sejam direcionados conforme a urgência. Além disso, o controle eficaz do tráfego e o isolamento do local do acidente são cruciais para permitir um acesso rápido e seguro das equipes de resgate. A escolta eficiente de ambulâncias, coordenada por batedores policiais, é vital para reduzir o tempo de deslocamento e melhorar os prognósticos dos pacientes. Por fim o artigo propõe uma atuação conjunta entre a Polícia Militar e o Corpo de Bombeiros em grandes centros urbanos, com a criação de POPs para garantir uma resposta coordenada e eficiente em emergências. A integração das forças e a definição clara de procedimentos visam aprimorar a preparação e a capacidade de resposta das autoridades, assegurando um atendimento eficaz e a maximização das chances de sobrevivência em acidentes com múltiplas vítimas.
{"title":"Integrando Polícia Militar e Corpo de Bombeiros: estratégias para atendimento eficiente em acidentes com múltiplas vítimas em centros urbanos","authors":"Omar Bail, Adriano Cristiano Lazarotto","doi":"10.34117/bjdv10n6-008","DOIUrl":"https://doi.org/10.34117/bjdv10n6-008","url":null,"abstract":"O artigo apresenta uma metodologia multifacetada que integra revisão bibliográfica e a proposição de diretrizes para melhorar a resposta em acidentes com múltiplas vítimas em áreas urbanas de tráfego intenso. Iniciando com uma revisão abrangente da literatura sobre atendimento pré-hospitalar (APH), triagem, controle de tráfego e escolta policial para ambulâncias, o estudo baseou-se em normas técnicas e acadêmicas para fundamentar suas propostas. A partir dessas informações, foram propostas o estabelecimento de diretrizes específicas para a integração entre a Polícia Militar e o Corpo de Bombeiros do Paraná, incluindo Procedimentos Operacionais Padrão (POPs) para treinamento conjunto, triagem de vítimas, controle de tráfego e escolta de ambulâncias. A triagem, destacada pelo método START, é essencial para priorizar vítimas em situações de recursos limitados, garantindo que os cuidados sejam direcionados conforme a urgência. Além disso, o controle eficaz do tráfego e o isolamento do local do acidente são cruciais para permitir um acesso rápido e seguro das equipes de resgate. A escolta eficiente de ambulâncias, coordenada por batedores policiais, é vital para reduzir o tempo de deslocamento e melhorar os prognósticos dos pacientes. Por fim o artigo propõe uma atuação conjunta entre a Polícia Militar e o Corpo de Bombeiros em grandes centros urbanos, com a criação de POPs para garantir uma resposta coordenada e eficiente em emergências. A integração das forças e a definição clara de procedimentos visam aprimorar a preparação e a capacidade de resposta das autoridades, assegurando um atendimento eficaz e a maximização das chances de sobrevivência em acidentes com múltiplas vítimas.","PeriodicalId":504671,"journal":{"name":"Brazilian Journal of Development","volume":"190 1‐2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141387219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cognitive empowerment plays a critical role in the banking sector in Sri Lanka as well as in the global financial industry which may enhance customer experience, efficient operations, effective decision making, innovations as well as adaptability while gaining an edge over competition. This study investigates how organizational culture (Clan, Adhocracy, Market, and Hierarchy) can enhance cognitive empowerment of bankers in Sri Lanka. A quantitative approach was used whereas, initially a preliminary investigation was conducted to gain a general understanding of the culture of few leading banks in Sri Lanka and eventually cascading down to four banks that covers all four cultures. Further, 239 responses were received through a structured questionnaire from four leading banks covering all four cultures. Results showed higher levels of cognitive empowerment in entities with strong clan, adhocracy, and market cultures, while higher hierarchy culture was associated with lower levels of cognitive empowerment.
{"title":"The impact of organizational culture on cognitive empowerment in selected banks in Colombo District in Sri Lanka","authors":"Walliwala Gamage Nadeesha Nirmanee Abeyatunge","doi":"10.34117/bjdv10n5-041","DOIUrl":"https://doi.org/10.34117/bjdv10n5-041","url":null,"abstract":"Cognitive empowerment plays a critical role in the banking sector in Sri Lanka as well as in the global financial industry which may enhance customer experience, efficient operations, effective decision making, innovations as well as adaptability while gaining an edge over competition. This study investigates how organizational culture (Clan, Adhocracy, Market, and Hierarchy) can enhance cognitive empowerment of bankers in Sri Lanka. A quantitative approach was used whereas, initially a preliminary investigation was conducted to gain a general understanding of the culture of few leading banks in Sri Lanka and eventually cascading down to four banks that covers all four cultures. Further, 239 responses were received through a structured questionnaire from four leading banks covering all four cultures. Results showed higher levels of cognitive empowerment in entities with strong clan, adhocracy, and market cultures, while higher hierarchy culture was associated with lower levels of cognitive empowerment.","PeriodicalId":504671,"journal":{"name":"Brazilian Journal of Development","volume":"42 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140969963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ribosomes are essential cellular organelles made up of rRNA and rproteins found in both prokaryotic and eukaryotic cells, and play an important role in protein synthesis. The functional ribosomes are synthesized through the process called ribosome biogenesis, which proceeds with the help of certain factors such as chaperones, ribosomal proteins, and GTPases. GTPases bind to the premature ribosomal subunit and function as a checkpoint, ensuring the proper assembly of other proteins. To aid this process, GTPase undergoes conformational changes, alternating between an active GTP-bound state and an inactive GDP bound state. YsxC is a GTPase that functions this way, to help in the maturation of 50S subunit. Although YsxC plays an important role in ribosome biogenesis, a detailed knowledge of how the GDP and GTPMg2+ states of YsxC assist in the switching process is yet to be realized. Therefore, a study on the GDP and GTP-Mg2+ bound states is done for YsxC GTPase of Bacillus subtilis by all-atom molecular dynamics simulation for a period of 500 ns. The simulations aided the analysis of the RMSD from which it was noticed that both the GDP and GTP-Mg2+ states of YsxC attained equilibration after 200ns. The analysis of the Rg for the systems showed that the GTP-Mg2+ system showed higher values, in comparison to the GDP system, indicating conformational changes in the two systems. Thus, a residue-wise calculation for the difference in the SASA (solvent accessible surface area) of the GTP-Mg2+ and GDP system is done, and it is noticed that the GTP-Mg2+ system, especially in the regions recognized as Switch I and Switch II had a higher difference in SASA value. In which Switch I’s Lys55 (positive residue) and Switch II’s Arg89 (positive residue) showed a distinct difference, indicating that Switch I has more accessibility to solvent. Giving rise to a supposition that the residue Lys55 attracts the negative rRNA and aids in the binding of YsxC with the premature 50S subunit in the GTP-Mg2+ bound state by associating with the rRNA. To fathom the role of the GTP-Mg2+ bound state in increasing the SASA value of Switch I region, a community network is constructed to extract the shortest path. More number of paths are observed between the selected residue in the GTP-Mg2+ bound state inferring that the increased SASA in the Lys55 is due to the stronger connection with the nucleotide. Overall this study suggest that enhanced surface exposure of YsxC’s Sw-I in the GTP-Mg2+ bound state facilitate the GTP-Mg2+ bound system to involve in ribosome biogenesis by interacting with ribosomal constituents (rRNA and rproteins).
核糖体是由原核细胞和真核细胞中的 rRNA 和 r 蛋白组成的重要细胞器，在蛋白质合成中发挥着重要作用。功能性核糖体是通过核糖体生物发生过程合成的，这一过程在某些因素（如伴侣蛋白、核糖体蛋白和 GTP 酶）的帮助下进行。GTPase 与未成熟的核糖体亚基结合，起着检查点的作用，确保其他蛋白质的正常组装。为了帮助这一过程，GTPase 会发生构象变化，在活跃的 GTP 结合态和不活跃的 GDP 结合态之间交替。YsxC 就是这样一种 GTPase，它有助于 50S 亚基的成熟。尽管 YsxC 在核糖体生物发生过程中发挥着重要作用，但人们对 YsxC 的 GDP 和 GTPMg2+ 状态如何帮助完成切换过程的详细了解仍有待实现。因此，我们通过 500 毫微秒的全原子分子动力学模拟，对枯草芽孢杆菌 YsxC GTPase 的 GDP 和 GTP-Mg2+ 结合态进行了研究。模拟有助于分析 RMSD，从中发现 YsxC 的 GDP 和 GTP-Mg2+ 状态都在 200 ns 后达到平衡。对这两个系统的 Rg 分析表明，与 GDP 系统相比，GTP-Mg2+ 系统的 Rg 值更高，这表明这两个系统的构象发生了变化。因此，对 GTP-Mg2+ 和 GDP 系统的 SASA（溶剂可及表面积）差异进行了残基计算，结果发现，GTP-Mg2+ 系统，尤其是开关 I 和开关 II 区域的 SASA 值差异较大。其中开关 I 的 Lys55（阳性残基）和开关 II 的 Arg89（阳性残基）显示出明显的差异，表明开关 I 对溶剂的可及性更高。由此推测，残基 Lys55 可吸引阴性 rRNA，并通过与 rRNA 结合，帮助 YsxC 与处于 GTP-Mg2+ 结合态的过早 50S 亚基结合。为了弄清 GTP-Mg2+ 结合状态在增加开关 I 区域 SASA 值中的作用，我们构建了一个群落网络来提取最短路径。在 GTP-Mg2+ 结合状态下，所选残基之间有更多的路径，推断 Lys55 的 SASA 值增加是由于与核苷酸的连接更强。总之，这项研究表明，在 GTP-Mg2+ 结合状态下，YsxC 的 Sw-I 表面暴露增强，有利于 GTP-Mg2+ 结合系统通过与核糖体成分（rRNA 和 r 蛋白）相互作用参与核糖体的生物生成。
{"title":"Molecular dynamics simulation studies and dynamic network analysis of Bacillus subtilis YsxC in GDP and GTP-Mg 2+ bound states","authors":"Shuchika Devaraj Biligere, Kavya Kallahalli Mohankumar, Upendra Nagarajachari, Krishnaveni Sannathammegowda","doi":"10.34117/bjdv10n5-044","DOIUrl":"https://doi.org/10.34117/bjdv10n5-044","url":null,"abstract":"Ribosomes are essential cellular organelles made up of rRNA and rproteins found in both prokaryotic and eukaryotic cells, and play an important role in protein synthesis. The functional ribosomes are synthesized through the process called ribosome biogenesis, which proceeds with the help of certain factors such as chaperones, ribosomal proteins, and GTPases. GTPases bind to the premature ribosomal subunit and function as a checkpoint, ensuring the proper assembly of other proteins. To aid this process, GTPase undergoes conformational changes, alternating between an active GTP-bound state and an inactive GDP bound state. YsxC is a GTPase that functions this way, to help in the maturation of 50S subunit. Although YsxC plays an important role in ribosome biogenesis, a detailed knowledge of how the GDP and GTPMg2+ states of YsxC assist in the switching process is yet to be realized. Therefore, a study on the GDP and GTP-Mg2+ bound states is done for YsxC GTPase of Bacillus subtilis by all-atom molecular dynamics simulation for a period of 500 ns. The simulations aided the analysis of the RMSD from which it was noticed that both the GDP and GTP-Mg2+ states of YsxC attained equilibration after 200ns. The analysis of the Rg for the systems showed that the GTP-Mg2+ system showed higher values, in comparison to the GDP system, indicating conformational changes in the two systems. Thus, a residue-wise calculation for the difference in the SASA (solvent accessible surface area) of the GTP-Mg2+ and GDP system is done, and it is noticed that the GTP-Mg2+ system, especially in the regions recognized as Switch I and Switch II had a higher difference in SASA value. In which Switch I’s Lys55 (positive residue) and Switch II’s Arg89 (positive residue) showed a distinct difference, indicating that Switch I has more accessibility to solvent. Giving rise to a supposition that the residue Lys55 attracts the negative rRNA and aids in the binding of YsxC with the premature 50S subunit in the GTP-Mg2+ bound state by associating with the rRNA. To fathom the role of the GTP-Mg2+ bound state in increasing the SASA value of Switch I region, a community network is constructed to extract the shortest path. More number of paths are observed between the selected residue in the GTP-Mg2+ bound state inferring that the increased SASA in the Lys55 is due to the stronger connection with the nucleotide. Overall this study suggest that enhanced surface exposure of YsxC’s Sw-I in the GTP-Mg2+ bound state facilitate the GTP-Mg2+ bound system to involve in ribosome biogenesis by interacting with ribosomal constituents (rRNA and rproteins).","PeriodicalId":504671,"journal":{"name":"Brazilian Journal of Development","volume":"35 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140971200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
International integration has been an outstanding trend of Vietnamese higher education for 20 years. The international integration of Vietnamese higher education is considered as a proactive step and has achieved many positive outcomes. By reviewing of relevant literature, this paper aims to basically assesses international integration process of Vietnamese higher education in terms of establishing viewpoints and policies. The findings show that international integration process of Vietnamese higher education has taken place later than the socio-economic fields but has rapid evolution. From the initial legal basis launched since 1998, higher education has continuously expanded its roadmap, institutionalized viewpoints and policies, and completed legal framework which lays a foundation for international integration. Despite some positive results, the Vietnamese higher education’s standards are still set low, which mainly involves the reform to build a better integration structure and start applying the global rules of higher education.
{"title":"International integration of vietnamese higher education – general assessment of progress, viewpoints and policies","authors":"Pham Văn Thinh","doi":"10.34117/bjdv10n5-043","DOIUrl":"https://doi.org/10.34117/bjdv10n5-043","url":null,"abstract":"International integration has been an outstanding trend of Vietnamese higher education for 20 years. The international integration of Vietnamese higher education is considered as a proactive step and has achieved many positive outcomes. By reviewing of relevant literature, this paper aims to basically assesses international integration process of Vietnamese higher education in terms of establishing viewpoints and policies. The findings show that international integration process of Vietnamese higher education has taken place later than the socio-economic fields but has rapid evolution. From the initial legal basis launched since 1998, higher education has continuously expanded its roadmap, institutionalized viewpoints and policies, and completed legal framework which lays a foundation for international integration. Despite some positive results, the Vietnamese higher education’s standards are still set low, which mainly involves the reform to build a better integration structure and start applying the global rules of higher education.","PeriodicalId":504671,"journal":{"name":"Brazilian Journal of Development","volume":"37 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140970943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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