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Understanding and Addressing the Impact of Parental Stress and Stigma in Raising Children with Autism Spectrum Disorder (ASD) in Low-Resource Settings 在低资源环境中养育自闭症谱系障碍(ASD)儿童时,了解并应对家长压力和耻辱感的影响
Pub Date : 2024-04-02 DOI: 10.59298/iaajb/2024/122.566011
Mugisha Samuel, Edward Bantu, Faith Nakalema
The burden on parents raising children with Autism Spectrum Disorder (ASD) is escalating globally, particularly in middle and low-income countries, where access to resources and support is limited. This study aimed to investigate the levels of stress, stigma, and coping strategies among parents of children with ASD in Kawempe Division, Kampala, Uganda. Through a sample of 28 parents drawn from Katalemwa Cheshire Home, data was collected using self-administered questionnaires and analyzed using descriptive statistics. The results revealed very high levels of stress and stigma among parents, as evidenced by a grand mean of 3.71 (SD = 0.79) for stress and 3.57 (SD = 0.55) for stigma. These stressors encompassed various domains, including financial difficulties, marital conflicts, and psychological strain resulting from societal discrimination. Parents reported experiencing feelings of shame, embarrassment, and hopelessness, exacerbated by societal misconceptions and the lack of support systems. Notably, the prevalence of anxiety symptoms among parents (45.9%) surpassed previous estimates, indicating a significant mental health burden within this population. Furthermore, the coping mechanisms employed by parents were found to be inadequate, with a grand mean of 1.78 (SD = 0.77) for coping strategies. Positive coping strategies, such as seeking new job opportunities for their children, were limited, while negative coping mechanisms, including substance abuse and rudeness, were more prevalent. These findings underscore the urgent need for tailored interventions to equip parents with effective coping strategies and stress management techniques. The study highlights the challenges faced by parents raising children with ASD in low resource settings, shedding light on the psychological, social, and economic burdens they endure. Addressing these challenges requires comprehensive support systems, including training programs, workshops, and access to resources aimed at empowering parents and enhancing their well-being. By understanding and addressing the specific stressors and coping mechanisms within this population, interventions can be developed to alleviate the burdens faced by parents, ultimately improving their quality of life and promoting the holistic development of children with ASD. Keywords: Stress, Stigma, Coping Strategies, Autism Spectrum Disorder, Raising children
在全球范围内,抚养自闭症谱系障碍(ASD)儿童的父母所承受的负担日益加重,尤其是在资源和支持有限的中低收入国家。本研究旨在调查乌干达坎帕拉 Kawempe 区自闭症儿童家长的压力、耻辱感和应对策略水平。研究人员从卡塔莱姆瓦-切希尔之家抽取了 28 名家长作为样本,使用自填式问卷收集数据,并使用描述性统计进行分析。结果显示,家长的压力和耻辱感水平非常高,压力总平均值为 3.71(标准差 = 0.79),耻辱感总平均值为 3.57(标准差 = 0.55)。这些压力因素涉及多个领域,包括经济困难、婚姻矛盾以及社会歧视造成的心理压力。据报告,家长们感到羞耻、尴尬和绝望,而社会的误解和支持系统的缺乏又加剧了这种情绪。值得注意的是,父母中焦虑症状的流行率(45.9%)超过了之前的估计,这表明这一人群的心理健康负担很重。此外,研究还发现,家长采用的应对机制并不完善,应对策略的总平均值为 1.78(标准差 = 0.77)。积极的应对策略有限,如为子女寻找新的工作机会,而消极的应对机制则更为普遍,包括滥用药物和粗鲁无礼。这些研究结果突出表明,迫切需要采取有针对性的干预措施,让家长掌握有效的应对策略和压力管理技巧。这项研究强调了在资源匮乏的环境中抚养患有 ASD 儿童的父母所面临的挑战,揭示了他们所承受的心理、社会和经济负担。应对这些挑战需要全面的支持系统,包括培训计划、研讨会和获取资源的途径,目的是增强家长的能力,提高他们的幸福感。通过了解和解决这一群体的特殊压力和应对机制,可以制定干预措施,减轻家长的负担,最终改善他们的生活质量,促进 ASD 儿童的全面发展。关键词压力 耻辱 应对策略 自闭症谱系障碍 养育子女
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引用次数: 0
Factors influencing Teenage Pregnancy among Girls attending Kampala International University Teaching Hospital, Bushenyi, Uganda 影响乌干达布申伊坎帕拉国际大学教学医院就诊少女怀孕的因素
Pub Date : 2024-03-03 DOI: 10.59298/iaajb/2024/121.4858.11
Alal Levi Tema
Teenage pregnancy and subsequent childbirth to women less than 20 years of age continue to be a major global public health concern in both developed and developing countries, affecting more than 16 million girls and young women, or an estimated 11% of all births worldwide. This study determined the factors influencing teenage pregnancy among teenage girls aged 13–19 attending ANC at KIU-TH, Bushenyi District. A cross-sectional study design was employed for this study. Quantitative data was collected using structured interviews. Questionnaire tools were checked for their accuracy and data completeness, then the data was coded and entered into Epi Info version 7, then exported into SPSS version 22.0 for analysis. A binary logistic regression model was used to identify the determinant factors. A collinearity diagnostic test was conducted using tolerance to check for collinearity between independent variables and the interaction effect. Variables in the bivariable analysis having a p-value <0.2 were considered for the multivariate analysis to adjust the confounders. The strength and presence of a statistical association were assessed by the OR, p-value, and 95% confidence interval (95% CI). Variables with a p-value ≤0.05 were considered statistically significant determinants of teenage pregnancy. The Hosmer-Lemeshow goodness-offit test (p = 0.9289) was used to assess the fitness of the model. A total of 310 adolescents were included in the study, with a response rate of 100%. The majority (39.7%) were aged 16–17, and more than half (59.0%) were from rural areas. The proportion of teenage pregnancies among study participants was 19.0. In the multivariate logistic regression model, age, residence, parents’ marital status, level of education, monthly income, substance abuse, history of use of contraceptives, age of first sexual contact, and awareness of safe sex were statistically significant. The study showed a high prevalence of teenage pregnancy. Age, residence, parents’ marital status, level of education, monthly income, substance abuse, history of use of contraceptives, age of first sexual contact, and awareness of safe sex were found to have a statistically significant association. Keywords: Teenage pregnancy, Childbirth, Girls, Marital status, Age.
在发达国家和发展中国家,少女怀孕及随后不到 20 岁的女性生育仍然是全球关注的一个主要公共卫生问题,受影响的少女和年轻女性超过 1600 万,估计占全球新生儿总数的 11%。本研究确定了在布塞尼区 KIU-TH 接受产前保健的 13-19 岁少女中少女怀孕的影响因素。本研究采用了横断面研究设计。通过结构化访谈收集定量数据。先检查问卷工具的准确性和数据的完整性,然后对数据进行编码并输入 Epi Info 7 版,再导出到 SPSS 22.0 版进行分析。采用二元逻辑回归模型确定决定因素。利用容差进行了共线性诊断检测,以检查自变量和交互效应之间是否存在共线性。二变量分析中的变量如果 p 值小于 0.2,则考虑进行多变量分析,以调整混杂因素。统计学关联的强度和存在与否由 OR、P 值和 95% 置信区间(95% CI)来评估。P值≤0.05的变量被认为是少女怀孕的重要统计学决定因素。Hosmer-Lemeshow goodness-offit 检验(p = 0.9289)用于评估模型的适宜性。共有 310 名青少年参与了研究,回复率为 100%。大多数(39.7%)青少年的年龄在 16-17 岁之间,超过一半(59.0%)的青少年来自农村地区。研究参与者中少女怀孕的比例为 19.0。在多变量逻辑回归模型中,年龄、居住地、父母婚姻状况、教育程度、月收入、药物滥用、避孕药具使用史、初次性接触年龄和安全性行为意识均具有统计学意义。研究表明,少女怀孕的发生率很高。研究发现,年龄、居住地、父母婚姻状况、教育水平、月收入、药物滥用、避孕药具使用史、初次性接触年龄和安全性行为意识在统计学上有显著关联。关键词少女怀孕 分娩 女孩 婚姻状况 年龄
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引用次数: 0
The Impact of Breast Cancer Awareness Campaigns on Women's Knowledge, Attitudes, and Practices in Uganda's Kampala District 乌干达坎帕拉地区乳腺癌宣传活动对妇女知识、态度和做法的影响
Pub Date : 2024-02-23 DOI: 10.59298/iaajb/2024/121.3247.11
Victoria A. Nyineizooba, Joel Isabirye
In Uganda, breast cancer affects 116 out of every 100,000 women. Worldwide, the yearly incidence rate of breast cancer (BRCA) is more than 1 million cases and more than 411,000 deaths. In underdeveloped nations, the survival rate is less than 50%, while in industrialized nations, it is 90%. Studies have shown that this is caused by delayed diagnosis and identification of breast cancer (BRCA), as well as by inadequate understanding, attitudes, and practices about BRCA, its causes, risk factors, and screening methods. Since the success of these campaigns to raise awareness, alter negative attitudes toward BRCA prevention and treatment, and improve the use of screening methods is highly dependent on their influence, the MTN Foundation, National Breast Cancer Coalition, Breast Cancer Action, and Miss University Uganda campaigners have resorted to aggressive awareness and sensitization programs aimed at increasing knowledge, changing attitudes, and improving the practice of all necessary screening procedures. To determine the degree of awareness and exposure, knowledge level, attitude, and screening practice among women in Kampala District, a survey and in-person interviews were employed. The causes of unhealthy habits and their effects were explained by the Health Believe Model and the Attitude Change Theory. The results showed a cursory understanding of BRCA symptoms, causes, genetic testing, BSE, and CBE. Strongly negative emotional and psychological beliefs also impact that attitude. As a result, the study stressed the need of preventive rather than curative methods and acknowledged the contribution of breast cancer campaigns to the cause. Keywords: Breast cancer, Campaigns, Self-examination, Risk factors.
在乌干达,每 10 万名妇女中就有 116 人罹患乳腺癌。全世界每年的乳腺癌(BRCA)发病率超过 100 万例,死亡人数超过 41.1 万。在不发达国家,存活率不到 50%,而在工业化国家,存活率则高达 90%。研究表明,造成这种情况的原因是对乳腺癌(BRCA)的诊断和识别延迟,以及对 BRCA、其病因、风险因素和筛查方法的认识、态度和实践不足。由于提高意识、改变对 BRCA 预防和治疗的消极态度以及改进筛查方法的使用这些活动的成功与否在很大程度上取决于其影响力,因此 MTN 基金会、全国乳腺癌联盟、乳腺癌行动和乌干达小姐大学的宣传人员采取了积极的提高认识和宣传计划,旨在增加知识、改变态度和改进所有必要筛查程序的实践。为了确定坎帕拉地区妇女的认识和接触程度、知识水平、态度和筛查做法,我们采用了调查和面谈的方式。健康信念模型和态度改变理论解释了不健康习惯的原因及其影响。结果显示,人们对 BRCA 症状、病因、基因检测、BSE 和 CBE 的了解比较粗浅。强烈的负面情绪和心理信念也会影响这种态度。因此,研究强调了预防而非治疗方法的必要性,并肯定了乳腺癌宣传活动对这一事业的贡献。关键词乳腺癌 宣传活动 自我检查 风险因素
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引用次数: 0
Undernutrition among HIV-positive Children of age 1-5 Years attending the ART Clinic in Bushenyi Health Centre IV Ishaka-Bushenyi Municipality, Bushenyi District 布谢尼区伊沙卡-布谢尼市布谢尼第四健康中心抗逆转录病毒疗法门诊就诊的 1-5 岁艾滋病毒抗体阳性儿童的营养不良情况
Pub Date : 2024-02-23 DOI: 10.59298/iaajb/2024/121.7885.11
Ssesanga Godfrey
Worldwide, more than 3.4 million children under the age of 5 are infected with HIV. Both acute and chronic malnutrition are major problems for HIV-positive children living in resource-limited settings. In Uganda, the data from ART clinics revealed that up to 23% of mothers and 50% of children who were on treatment have moderate acute malnutrition. To understand undernutrition in HIV-positive children aged 1–5 years in Bushenyi District, western Uganda, a study was conducted in Bushenyi Health Centre IV to determine the common forms of undernutrition, mother awareness of undernutrition, and the management protocol conferred on HIV-positive children. There were 61 participants, of whom 54% were female and 46% were male; 41% were between the ages of 1-2 years; 31% were 5 years; and 28% were 3–4 years. The study indicated that 82% of the guardians had good knowledge about undernutrition, with 18% having little knowledge of the problem in HIV-positive children. In this study, using the z-score in data analysis, there were 3 children who were less than -2 SD (-2 standard deviation), and the overall prevalence of undernutrition was 5%. The guardians were asked whether they had heard about Ready-to-Use Therapeutic Food (RUTF) in the hospital management of undernutrition in HIV-positive children, and 79% of the respondents confirmed that they had heard about it and that they preferred their undernourished children to be managed with that form from the health units. However, 21% preferred managing their children from home without getting to the health unit. The prevalence of undernutrition in HIV-affected children aged 1–5 years is high, and the majority of the children are underweight with moderate acute malnutrition. Some HIV-positive caretakers still have inadequate knowledge about undernutrition in their children. Some people lack knowledge about the management of undernutrition in HIV-positive children. Keywords: HIV, ART, Malnutrition, Undernutrition
全世界有 340 多万 5 岁以下儿童感染了艾滋病毒。对于生活在资源有限环境中的艾滋病毒阳性儿童来说,急性和慢性营养不良都是主要问题。在乌干达,抗逆转录病毒疗法诊所的数据显示,高达 23% 的接受治疗的母亲和 50% 的儿童患有中度急性营养不良。为了了解乌干达西部 Bushenyi 地区 1-5 岁 HIV 阳性儿童的营养状况,我们在 Bushenyi 第四健康中心开展了一项研究,以确定常见的营养不良形式、母亲对营养不良的认识以及对 HIV 阳性儿童的管理方案。共有 61 名参与者,其中女性占 54%,男性占 46%;41% 的儿童年龄在 1-2 岁之间;31% 的儿童年龄在 5 岁之间;28% 的儿童年龄在 3-4 岁之间。研究表明,82% 的监护人对营养不良有较好的了解,18% 的监护人对艾滋病毒呈阳性儿童的营养不良问题知之甚少。在这项研究中,使用z-分数进行数据分析,有3名儿童低于-2 SD(-2标准差),营养不良的总体发生率为5%。监护人被问及是否听说过即食治疗食品(RUTF)在医院管理艾滋病病毒抗体阳性儿童营养不良的过程中的作用,79%的受访者确认听说过,并表示他们更愿意自己的营养不良儿童在医疗单位接受这种形式的管理。不过,21% 的受访者倾向于在家里管理自己的孩子,而不去医疗机构。在 1-5 岁受艾滋病毒影响的儿童中,营养不良的发生率很高,大多数儿童体重不足,并伴有中度急性营养不良。一些艾滋病毒呈阳性的看护者对儿童营养不良的认识仍然不足。一些人对艾滋病病毒抗体阳性儿童营养不良的管理缺乏了解。关键词艾滋病毒 抗逆转录病毒疗法 营养不良 营养不足
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引用次数: 0
Factors Associated with Malaria in Pregnancy among Women Attending Fort Portal Regional Referral Hospital in Fort Portal City, Western Uganda 乌干达西部波尔塔尔堡市波尔塔尔堡地区转诊医院就诊妇女妊娠期疟疾的相关因素
Pub Date : 2024-02-23 DOI: 10.59298/iaajb/2024/121.6069.11
Brian Ruvusha Kiiza
Globally, there was a significant decrease in the number of malaria-risk pregnancies between 2007 and 2020. The risk of Plasmodium falciparum or Plasmodium vivax malaria increased by 25% in Africa compared to 2007. Due to the fast-expanding population and associated rise in pregnancies in malaria-endemic areas, the number of people at risk in Africa has increased despite malaria rates declining in the region. This study determined the prevalence and factors associated with malaria in pregnancy among women attending Fort Portal Regional Referral Hospital. This was a single-center health facility-based cross-sectional study. Data was collected using a face-to-face interview through a structured questionnaire from willing participants. After collecting the data, the principal investigator checked the completed questionnaires for consistency and completeness. Data was coded, cleaned, and entered into the computer using Microsoft Excel, and then analyzed using SPSS version 20. Logistic regression analysis was done to ascertain the relationship between dependent and independent variables. Descriptive statistics were summarized in the form of frequency tables, pie charts, p-values, and odds ratios. A total of 253 pregnant mothers attending ANC were enrolled in this study. The majority (38.3%) of the study participants were aged 30-39 years, attained secondary education (52.2%), earned 100,000–200,000 per month (56.9%), and were housewives (51.0%). In this study, the prevalence of malaria in pregnancy was 10.3%. Age, level of education, income status, and residence, use of an ITN, gravidity, and ANC follow-up were significantly associated with malaria in pregnancy at multivariate logistic regression analysis. Malaria continues to be a major public health issue among pregnant mothers. Age, level of education, income status, and residence, use of an ITN, gravidity, and ANC follow-up were factors significantly associated with malaria in pregnancy. Keywords: Pregnancies, Malaria, Plasmodium, ITN, ANC.
在全球范围内,2007 年至 2020 年间疟疾风险怀孕的数量大幅下降。与 2007 年相比,非洲罹患恶性疟原虫或间日疟原虫疟疾的风险增加了 25%。由于人口迅速膨胀,疟疾流行地区的怀孕人数也随之增加,尽管非洲地区的疟疾发病率在下降,但面临风险的人数却在增加。这项研究确定了在波特尔堡地区转诊医院就诊的妇女中妊娠期疟疾的发病率和相关因素。这是一项基于单中心医疗机构的横断面研究。研究人员通过结构化问卷对有意愿的参与者进行面对面访谈,收集数据。收集完数据后,主要调查人员会检查已填写问卷的一致性和完整性。数据经编码、清理后用 Microsoft Excel 输入计算机,然后用 SPSS 20 版进行分析。为确定因变量和自变量之间的关系,进行了逻辑回归分析。描述性统计以频率表、饼图、P 值和几率的形式进行总结。共有 253 名接受产前检查的孕妇参与了本研究。大多数研究参与者(38.3%)的年龄在 30-39 岁之间,受过中等教育(52.2%),月收入在 10-20 万之间(56.9%),是家庭主妇(51.0%)。在这项研究中,妊娠期疟疾的发病率为 10.3%。在多变量逻辑回归分析中,年龄、教育水平、收入状况、居住地、使用驱虫蚊帐、孕早期和产前检查随访与妊娠期疟疾显著相关。疟疾仍然是孕产妇的一个主要公共卫生问题。年龄、教育水平、收入状况、居住地、使用驱虫蚊帐、孕期和产前检查随访是与妊娠期疟疾显著相关的因素。关键词妊娠、疟疾、疟原虫、驱虫蚊帐、产前检查。
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引用次数: 0
Assessment of Implementation of Malaria Control Strategies among Pregnant Mothers Attending Antenatal Care at Bumanya Health Centre IV in Kaliro District 评估卡利罗区布曼亚第四保健中心产前检查孕产妇疟疾控制策略的实施情况
Pub Date : 2024-02-23 DOI: 10.59298/iaajb/2024/121.2031.11
Afaayo Benjamin
Although a high proportion of pregnant women had an antenatal care (ANC) visit at least once during pregnancy, the coverage level of intermittent preventive treatment of malaria in pregnancy (IPTp-SP) and insecticide-treated bednets (ITNs) remains low in Sub-Saharan Africa. A hospital-based descriptive cross-sectional study was carried out. The outcome of the survey revealed that the majority of participants, 79%, were above 20 years old, with a mean (+/-SD) age of 25.6 (+/-SD) years. The survey also revealed that 62.67% of the participants knew about IPTp; the biggest number of participants (86.67%) reported utilizing IPTp during their current pregnancy, while 13.33% did not take IPTp. Occupation, gestational age, several ANC visits, and information about IPTp were significantly associated with IPTp uptake. The current study explored malaria IPTp uptake among pregnant women attending ANC at Bumanya HCIV. It established that an increased number of ANC visits, providing IPTp information to pregnant women, and the gestational age of pregnancy resulted in increased uptake of IPTp and thus reduced incidences of malaria cases. Keywords: Pregnancy, Women, ANC, IPTp, Malaria, Gestational age.
尽管很高比例的孕妇在怀孕期间至少接受过一次产前检查(ANC),但在撒哈拉以南非洲地区,妊娠期疟疾间歇性预防治疗(IPTp-SP)和驱虫蚊帐(ITNs)的覆盖率仍然很低。我们开展了一项基于医院的描述性横断面研究。调查结果显示,79%的参与者年龄在 20 岁以上,平均(+/-SD)年龄为 25.6(+/-SD)岁。调查还显示,62.67%的参与者知道 IPTp;最多的参与者(86.67%)表示在本次怀孕期间使用了 IPTp,13.33%的参与者没有服用 IPTp。职业、孕龄、产前检查次数和有关 IPTp 的信息与 IPTp 服用率有显著相关性。本研究探讨了在布玛雅医疗中心(Bumanya HCIV)接受产前检查的孕妇中疟疾综合治疗方案的服用情况。研究结果表明,增加产前检查次数、向孕妇提供 IPTp 信息以及孕妇的孕龄可提高孕妇对 IPTp 的摄入量,从而减少疟疾病例的发生。关键词妊娠;妇女;产前检查;IPTp;疟疾;妊娠期。
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引用次数: 0
Prevalence and Associated Factors of Urinary Tract Infections among Diabetes Mellitus Patients at KIU-TH from January to December 2022 2022 年 1 月至 12 月 KIU-TH 糖尿病患者尿路感染的流行率和相关因素
Pub Date : 2024-02-23 DOI: 10.59298/iaajb/2024/121.7077.11
Priscilla Kangume
Globally, an estimated 150 million individuals are affected by urinary tract infections (UTIs) every year, with a significant number of those affected being diabetics. The International Diabetes Federation (IDF) reported that in the year 2019, there were about 60 million cases of patients suffering from diabetes who developed UTIs. The study assessed the prevalence and associated factors of urinary tract infections among diabetic mellitus patients in the medical ward at KIUTH. The objectives were to find out the prevalence and the factors associated with urinary tract infections among diabetic patients in the medical ward of KIU-TH. The study was descriptive, and it involved 87 patient files selected by purposive sampling, in which a checklist was the main tool of data collection. The study showed that female gender was significantly associated with the occurrence of urinary tract infection in diabetic patients at OR 0.17 (0.05–4.29) and PV 0.01. The study also shows that having other disease comorbidities was significantly associated with the occurrence of UTI among diabetic patients at OR 0.58 (0.35-8.07) and PV 0.002. The study also shows that having late diabetic disease among diabetic patients was also significantly associated with the occurrence of UTI among diabetic patients at OR 0.69 (0.35-8.19) and PV 0.004. The study concluded that 48 (55.2%) of diabetic patients had had a urinary tract infection, and therefore the study recommends that diabetic patients should be health educated on the causes and control of UTI so as to prevent their occurrences. The study also recommends that the government increase service provisions like treatments to reduce the occurrence of opportunistic conditions in UTIs, and the patients should be encouraged to seek regular medical checkups so that they monitor disease progression. Keywords: Diabetics, UTIs, Patients, Diabetes mellitus.
据估计,全球每年有 1.5 亿人受到尿路感染(UTI)的影响,其中相当一部分是糖尿病患者。国际糖尿病联合会(IDF)报告称,2019年约有6000万例糖尿病患者患上尿路感染。这项研究评估了基辅理工大学医院内科病房糖尿病患者尿路感染的患病率和相关因素。研究目的是找出九龙塘国际大学附属医院内科病房糖尿病患者尿路感染的发病率和相关因素。该研究为描述性研究,通过有目的的抽样选出了87份患者档案,并以核对表作为收集数据的主要工具。研究显示,女性性别与糖尿病患者尿路感染的发生有明显相关性,OR值为0.17(0.05-4.29),PV值为0.01。研究还显示,糖尿病患者合并其他疾病与尿路感染的发生明显相关,OR 值为 0.58(0.35-8.07),PV 值为 0.002。研究还显示,糖尿病患者的晚期糖尿病疾病也与糖尿病患者尿毒症的发生明显相关,OR 值为 0.69(0.35-8.19),PV 值为 0.004。研究得出的结论是,48 名(55.2%)糖尿病患者曾发生过尿路感染,因此研究建议对糖尿病患者进行健康教育,使其了解尿路感染的原因和控制方法,以预防尿路感染的发生。研究还建议政府增加治疗等服务,以减少尿路感染机会性疾病的发生,并应鼓励患者定期体检,以监测疾病的进展情况。关键词糖尿病人 尿毒症 患者 糖尿病
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引用次数: 0
Evaluating the Predictive Efficacy of Dipstick Urinalysis for Detecting Urinary Tract Infections in Febrile Children Under Five Years of Age at Federal Medical Centre, Owerri, Imo State, Nigeria 评估尼日利亚伊莫州奥韦里联邦医疗中心采用浸量尺尿液分析法检测五岁以下发热儿童尿路感染的预测效果
Pub Date : 2024-02-18 DOI: 10.59298/iaajb/2024/121.11.19
N. U. M., Esezobor C. I., Iregbu F. U., Ushie S. N.
This study aimed to assess the predictive efficacy of dipstick urinalysis in detecting urinary tract infections (UTI) among febrile children under five years of age at the Federal Medical Centre, Owerri, Imo State, Nigeria. The research involved a hospital-based descriptive cross-sectional study, analyzing the diagnostic performance of nitrite and leucocyte esterase tests on urine dipsticks. The results revealed low sensitivity but high specificity for both tests, suggesting their potential role in excluding UTI. The findings emphasize the importance of combining dipstick urinalysis with urine culture for accurate diagnosis in febrile children. Keywords: Urinary tract infections, Dipstick urinalysis, Febrile children, Nitrite, Leucocyte esterase, Diagnostic efficacy, Nigeria.
本研究旨在评估尼日利亚伊莫州奥韦里联邦医疗中心的尿液浸量棒检测法在检测五岁以下发热儿童尿路感染(UTI)方面的预测效果。该研究是一项基于医院的描述性横断面研究,分析了尿液浸渍棒上的亚硝酸盐和白细胞酯酶检测的诊断性能。结果显示,这两种检验的灵敏度较低,但特异性较高,表明它们在排除尿道炎方面具有潜在作用。研究结果强调了结合浸量棒尿液分析和尿培养对发热儿童进行准确诊断的重要性。关键词尿路感染 量表尿液分析 发热儿童 亚硝酸盐 白细胞酯酶 诊断效果 尼日利亚
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引用次数: 0
Anemia as a Prognostic Marker for Disease Progression in HIV Infection 贫血是艾滋病病毒感染者病情恶化的预兆标志
Pub Date : 2023-12-14 DOI: 10.59298/iaajb/2023/3.2.23310
E. Obeagu, G. U. Obeagu, E. Alum, Ugwu Okechukwu Paul-Chima
Anemia, a prevalent hematologic manifestation in individuals living with Human Immunodeficiency Virus (HIV) infection, has garnered considerable attention as a prognostic indicator for disease progression and adverse clinical outcomes. This abstract presents a comprehensive review elucidating the intricate relationship between anemia and the progression of HIV infection, incorporating epidemiological trends, underlying pathophysiological mechanisms, clinical implications, and prognostic significance. Despite advances in antiretroviral therapy (ART), anemia remains a frequent complication in HIVinfected individuals, posing substantial challenges to patient management. This paper aims to provide a nuanced understanding of anemia's role as a prognostic marker, surpassing its conventional characterization as a hematologic abnormality in the context of HIV infection. Anemia's role as a predictive marker for adverse clinical outcomes in HIV patients is explored, encompassing increased mortality rates, heightened risk of opportunistic infections, accelerated disease progression, and compromised quality of life. The review delves into its prognostic significance, shaping therapeutic decisions and prognostic assessments. This paper encapsulates the criticality of anemia as a prognostic marker for disease progression in HIV infection. Understanding its epidemiology, pathophysiological mechanisms, clinical implications, and prognostic significance is pivotal for informed clinical decision-making, prognostic assessments, and optimizing care paradigms in HIV management. Keywords: Anemia, Prognostic Marker, Disease Progression and HIV
贫血是人类免疫缺陷病毒(HIV)感染者的一种常见血液学表现,作为疾病进展和不良临床结果的预后指标,它已引起了广泛关注。本摘要通过流行病学趋势、潜在的病理生理机制、临床影响和预后意义等方面,全面综述了贫血与 HIV 感染进展之间的复杂关系。尽管抗逆转录病毒疗法(ART)取得了进展,但贫血仍是 HIV 感染者的常见并发症,给患者管理带来了巨大挑战。本文旨在对贫血作为预后标志物的作用提供一个细致入微的理解,超越其作为 HIV 感染情况下血液学异常的传统特征。本文探讨了贫血作为艾滋病患者不良临床结局预测指标的作用,包括增加死亡率、增加机会性感染风险、加速疾病进展和影响生活质量。综述深入探讨了其对预后的影响,从而影响治疗决策和预后评估。本文概括了贫血作为艾滋病病毒感染者疾病进展预后标志的重要性。了解贫血的流行病学、病理生理学机制、临床影响和预后意义,对于做出明智的临床决策、预后评估和优化 HIV 管理中的护理模式至关重要。关键词贫血 预后标志物 疾病进展与 HIV
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引用次数: 0
Advancements in Immune Augmentation Strategies for HIV Patients 艾滋病患者免疫增强策略的进展
Pub Date : 2023-12-14 DOI: 10.59298/iaajb/2023/1.2.23310
E. Obeagu, G. U. Obeagu, E. Alum, Ugwu Okechukwu Paul-Chima
The management of HIV has witnessed a transformative shift owing to innovative approaches aimed at bolstering immune status in affected individuals. The landscape of HIV treatment has undergone a profound transformation with the emergence of innovative approaches dedicated to fortifying the immune status of individuals living with the virus. This abstract provides a succinct yet comprehensive overview of groundbreaking strategies aimed at augmenting immune health in HIV patients. Encompassing advancements in immunotherapy, personalized medicine, lifestyle modifications, and telemedicine, this overview highlights the promising trajectory and potential impact of these novel interventions in the realm of HIV care. By exploring the multifaceted dimensions of immune enhancement strategies, this abstract sets the stage for a deeper understanding of these innovative approaches and their pivotal role in shaping the future of HIV management. Keywords: HIV, immunotherapy, personalized medicine, lifestyle modifications, telemedicine, immune health, treatment strategies
由于出现了旨在增强感染者免疫力的创新方法,艾滋病病毒的管理发生了转变。随着致力于强化病毒感染者免疫状态的创新方法的出现,艾滋病治疗的格局发生了深刻的变化。本摘要简明而全面地概述了旨在增强艾滋病患者免疫健康的突破性策略。本综述涵盖了免疫疗法、个性化医疗、生活方式调整和远程医疗等方面的进展,重点介绍了这些新型干预措施在艾滋病护理领域的发展轨迹和潜在影响。通过探讨免疫增强策略的多面性,本摘要为深入了解这些创新方法及其在塑造未来艾滋病管理中的关键作用奠定了基础。关键词HIV、免疫疗法、个性化医疗、生活方式调整、远程医疗、免疫健康、治疗策略
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引用次数: 0
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IAA Journal of Biological Sciences
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