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REGULATORY GUIDANCE FOR PRECLINICAL STUDIES OF CELL THERAPIES: PILOT SYNTHESIS OF HEALTH CANADA, FDA, AND EMA PERSPECTIVES 细胞疗法临床前研究监管指南:加拿大卫生部、FDA 和 EMA 观点的试点综述
Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.219
M.S. Jeffers, R. Bapuji, M. Lalu, D. Fergusson
{"title":"REGULATORY GUIDANCE FOR PRECLINICAL STUDIES OF CELL THERAPIES: PILOT SYNTHESIS OF HEALTH CANADA, FDA, AND EMA PERSPECTIVES","authors":"M.S. Jeffers, R. Bapuji, M. Lalu, D. Fergusson","doi":"10.1016/j.jcyt.2024.03.219","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.219","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":"7 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141229666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CONTROL MATERIALS TO IMPROVE COMPARABILITY BETWEEN FLUORESCENT IMAGE-BASED CELL VIABILITY MEASUREMENTS 对照材料,以提高基于荧光图像的细胞活力测量的可比性
Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.228
L. Pierce, M. Mohiuddin, A. Tona, J. Elliot, S. Sarkar
{"title":"CONTROL MATERIALS TO IMPROVE COMPARABILITY BETWEEN FLUORESCENT IMAGE-BASED CELL VIABILITY MEASUREMENTS","authors":"L. Pierce, M. Mohiuddin, A. Tona, J. Elliot, S. Sarkar","doi":"10.1016/j.jcyt.2024.03.228","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.228","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141229685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
INVESTIGATING THE INTERPLAY BETWEEN GUT MICROBIOME, MONOCYTES/MACROPHAGES, AND OSTEOARTHRITIS 研究肠道微生物组、单核细胞/巨噬细胞与骨关节炎之间的相互作用
Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.408
A. Ziyaeyan, A. F. Barazandeh, M. Rasti, S. Viswanathan
{"title":"INVESTIGATING THE INTERPLAY BETWEEN GUT MICROBIOME, MONOCYTES/MACROPHAGES, AND OSTEOARTHRITIS","authors":"A. Ziyaeyan, A. F. Barazandeh, M. Rasti, S. Viswanathan","doi":"10.1016/j.jcyt.2024.03.408","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.408","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":"21 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141229819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A VERSATILE SCREENING TECHNOLOGY TO DETERMINE TRANSCRIPTION FACTOR COMBINATIONS FOR REPROGRAMMING CELLULAR IDENTITY 确定转录因子组合以重塑细胞特性的多功能筛选技术
Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.477
Y. Choo, M. Tarunina, S. Luharia
{"title":"A VERSATILE SCREENING TECHNOLOGY TO DETERMINE TRANSCRIPTION FACTOR COMBINATIONS FOR REPROGRAMMING CELLULAR IDENTITY","authors":"Y. Choo, M. Tarunina, S. Luharia","doi":"10.1016/j.jcyt.2024.03.477","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.477","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":"5 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141230235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A 3-STEP METHOD FOR PREPARING CRYOPRESERVED SAMPLES OF APHERESIS PRODUCTS FOR POST-THAW ANALYSIS YIELDS A HIGH RECOVERY OF VIABLE CELLS 一种分 3 个步骤制备低温保存的无细胞抽吸产品样本以进行解冻后分析的方法可获得高活细胞回收率
Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.193
R. M. Sterner, D. Strasburg, S. Va, E. Jacob, M. DiGuardo
{"title":"A 3-STEP METHOD FOR PREPARING CRYOPRESERVED SAMPLES OF APHERESIS PRODUCTS FOR POST-THAW ANALYSIS YIELDS A HIGH RECOVERY OF VIABLE CELLS","authors":"R. M. Sterner, D. Strasburg, S. Va, E. Jacob, M. DiGuardo","doi":"10.1016/j.jcyt.2024.03.193","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.193","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":"5 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141230590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
UNIVERSAL AAV ENHANCER FOR IMPROVED VIRAL TITERS, QUALITY AND REDUCED PRODUCTION COSTS ACROSS SUSPENSION HEK PLATFORMS 通用 AAV 增强剂,可提高悬浮 Hek 平台的病毒滴度和质量,降低生产成本
Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.285
R. Reese, J. Swanson, A. Storck, J. Tse, L. Juckem
{"title":"UNIVERSAL AAV ENHANCER FOR IMPROVED VIRAL TITERS, QUALITY AND REDUCED PRODUCTION COSTS ACROSS SUSPENSION HEK PLATFORMS","authors":"R. Reese, J. Swanson, A. Storck, J. Tse, L. Juckem","doi":"10.1016/j.jcyt.2024.03.285","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.285","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":"32 35","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141233028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IMPROVING THE EFFICIENCY OF AAV GENE DELIVERY VECTORS VIA CAPSID DESIGN AND BIOPROCESS ENGINEERING 通过噬菌体设计和生物工艺工程提高 AAV 基因递送载体的效率
Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.421
L. Hall, Q.A. Rafiq
{"title":"IMPROVING THE EFFICIENCY OF AAV GENE DELIVERY VECTORS VIA CAPSID DESIGN AND BIOPROCESS ENGINEERING","authors":"L. Hall, Q.A. Rafiq","doi":"10.1016/j.jcyt.2024.03.421","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.421","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":"15 25","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141235193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
STABILIZED CARDIOMYOCYTE DIFFERENTIATION BY IMPROVING THE HOMOGENEITY AND SYNCHRONIZATION OF EPITHELIAL-MESENCHYMAL TRANSITION IN CELL AGGREGATES 通过提高细胞聚集的均匀性和上皮-间质转化的同步性,稳定心肌细胞的分化
Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.451
Y. Cui, M. Kim, M. Kino-oka
{"title":"STABILIZED CARDIOMYOCYTE DIFFERENTIATION BY IMPROVING THE HOMOGENEITY AND SYNCHRONIZATION OF EPITHELIAL-MESENCHYMAL TRANSITION IN CELL AGGREGATES","authors":"Y. Cui, M. Kim, M. Kino-oka","doi":"10.1016/j.jcyt.2024.03.451","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.451","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":"7 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141230358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ABSOLUTE QUANTIFICATION OF GENOMIC TARGETS FOR CELL COUNTING USING DROPLET DIGITAL PCR 使用液滴数字 PCR 对细胞计数的基因组目标进行绝对定量
Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.387
S. Sarkar, M. Cauble, J. Almeida, H. He, D. Varisco
{"title":"ABSOLUTE QUANTIFICATION OF GENOMIC TARGETS FOR CELL COUNTING USING DROPLET DIGITAL PCR","authors":"S. Sarkar, M. Cauble, J. Almeida, H. He, D. Varisco","doi":"10.1016/j.jcyt.2024.03.387","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.387","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":"56 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141232105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HYPOXIA PRIMING AS A MINIMAL MANIPULATION STRATEGY TO ENHANCE THE REGENERATIVE & IMMUNOMODULATORY PROPERTIES OF MESENCHYMAL STEM CELLS DERIVED SMALL EXTRACELLULAR VESICLES 低氧引物是增强间充质干细胞衍生小细胞外囊泡再生和免疫调节特性的最低操作策略
Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.165
Y. Sharma, S. Mohanty
{"title":"HYPOXIA PRIMING AS A MINIMAL MANIPULATION STRATEGY TO ENHANCE THE REGENERATIVE & IMMUNOMODULATORY PROPERTIES OF MESENCHYMAL STEM CELLS DERIVED SMALL EXTRACELLULAR VESICLES","authors":"Y. Sharma, S. Mohanty","doi":"10.1016/j.jcyt.2024.03.165","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.165","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":"51 48","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141232332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Cytotherapy
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