Pub Date : 2023-12-18DOI: 10.21608/eajbsc.2023.330319
Fatima-Zahrae Aboubakr, Youssef Nouhi, Otmane El Brini, B. Benazzouz, Younes Filali-Zegzouti, Omar Akhouayri
. Human C-reactive protein (CRP) is an acute phase reactant involved in chronic and acute inflammation, which plays an important role in developing many diseases, such as type 2 diabetes (T2D). This study aimed to evaluate the association between CRP 1059G>C Polymorphism and predisposition to T2D in patients from a population of Morocco. We analyzed data from 212 patients with T2D and 158 controls. After the DNA is extracted from the blood samples, Polymerase Chain Reaction (PCR) and agarose gel electrophoresis are performed to determine the CRP gene's 1059G>C polymorphism. In the comparison between the control and patient groups, there was a significant difference in both genotype and allele frequencies (P < 0.0001 and P < 0.0001, respectively). The prevalence of GG and GC genotypes in diabetic patients was 96.7% and 3.3%, respectively, while in controls, it was 81.6% and 18.4%, respectively. The heterozygote GC was associated with a higher risk of T2D compared to the GG genotype (OR = 0.15, 95%CI = 0.06–0.35, P < 0.001). Regarding the allele frequencies, in the diabetic group, the G and C alleles were found at 98.3% and 1.7%, respectively, while in controls, they were present at frequencies of 90.8% and 9.2%, respectively. The CRP C allele was associated with a 0.16-fold decreased risk of T2D compared to the G allele (OR = 0.16, 95%CI = 0.07–0.38, P < 0.001). These results indicate a significant association between the CRP 1059G>C polymorphism and T2D in the Moroccan population.
{"title":"The 1059G>C Polymorphism in C-Reactive Protein Gene and Its Association with Susceptibility to Type 2 Diabetes in the Moroccan Population","authors":"Fatima-Zahrae Aboubakr, Youssef Nouhi, Otmane El Brini, B. Benazzouz, Younes Filali-Zegzouti, Omar Akhouayri","doi":"10.21608/eajbsc.2023.330319","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.330319","url":null,"abstract":". Human C-reactive protein (CRP) is an acute phase reactant involved in chronic and acute inflammation, which plays an important role in developing many diseases, such as type 2 diabetes (T2D). This study aimed to evaluate the association between CRP 1059G>C Polymorphism and predisposition to T2D in patients from a population of Morocco. We analyzed data from 212 patients with T2D and 158 controls. After the DNA is extracted from the blood samples, Polymerase Chain Reaction (PCR) and agarose gel electrophoresis are performed to determine the CRP gene's 1059G>C polymorphism. In the comparison between the control and patient groups, there was a significant difference in both genotype and allele frequencies (P < 0.0001 and P < 0.0001, respectively). The prevalence of GG and GC genotypes in diabetic patients was 96.7% and 3.3%, respectively, while in controls, it was 81.6% and 18.4%, respectively. The heterozygote GC was associated with a higher risk of T2D compared to the GG genotype (OR = 0.15, 95%CI = 0.06–0.35, P < 0.001). Regarding the allele frequencies, in the diabetic group, the G and C alleles were found at 98.3% and 1.7%, respectively, while in controls, they were present at frequencies of 90.8% and 9.2%, respectively. The CRP C allele was associated with a 0.16-fold decreased risk of T2D compared to the G allele (OR = 0.16, 95%CI = 0.07–0.38, P < 0.001). These results indicate a significant association between the CRP 1059G>C polymorphism and T2D in the Moroccan population.","PeriodicalId":505538,"journal":{"name":"Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology","volume":"18 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139173336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-18DOI: 10.21608/eajbsc.2023.330322
Dhuha Noori, H. Omear, S. Mohsin
Bachground : Polycystic ovary syndrome (PCOS) is a common condition that often leads to metabolic complications such as insulin resistance (IR) and obesity. Visfatin is a peptide that plays a role in endocrine, autocrine, and paracrine functions. Methods : Samples were collected from 90 women aged 16 to 40 years, divided into two groups. The PCOS group comprised 60 samples, with 30 women who had insulin resistance and 30 women who did not. The healthy group included 30 samples. The visfatin levels for all participants and performed genotyping for specific regions of the visfatin (rs1330082) gene using Real-time PCR were measured. The statistical significance is defined as p ≤ 0.05 for all comparisons. Results: The results showed that women with PCOS and insulin resistance had significantly higher levels of serum visfatin compared to other studies (6.640±0.3886, p <0.0001). However, there was no significant difference regarding the frequency of visfatin rs1330082 allele between the study groups. Conclusion: The research indicates that measuring serum visfatin levels could be a helpful tool for predicting insulin resistance in women with PCOS. However, we did not find any significant correlation between visfatin allele frequencies (rs1330082) and susceptibility to PCOS when compared to healthy controls.
{"title":"Measurement Visfatin Level and Its Genetic Polymorphisms (rs61330082) in Women with Polycystic Ovary Syndrome With and Without Insulin Resistance","authors":"Dhuha Noori, H. Omear, S. Mohsin","doi":"10.21608/eajbsc.2023.330322","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.330322","url":null,"abstract":"Bachground : Polycystic ovary syndrome (PCOS) is a common condition that often leads to metabolic complications such as insulin resistance (IR) and obesity. Visfatin is a peptide that plays a role in endocrine, autocrine, and paracrine functions. Methods : Samples were collected from 90 women aged 16 to 40 years, divided into two groups. The PCOS group comprised 60 samples, with 30 women who had insulin resistance and 30 women who did not. The healthy group included 30 samples. The visfatin levels for all participants and performed genotyping for specific regions of the visfatin (rs1330082) gene using Real-time PCR were measured. The statistical significance is defined as p ≤ 0.05 for all comparisons. Results: The results showed that women with PCOS and insulin resistance had significantly higher levels of serum visfatin compared to other studies (6.640±0.3886, p <0.0001). However, there was no significant difference regarding the frequency of visfatin rs1330082 allele between the study groups. Conclusion: The research indicates that measuring serum visfatin levels could be a helpful tool for predicting insulin resistance in women with PCOS. However, we did not find any significant correlation between visfatin allele frequencies (rs1330082) and susceptibility to PCOS when compared to healthy controls.","PeriodicalId":505538,"journal":{"name":"Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139176039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-14DOI: 10.21608/eajbsc.2023.330065
Muhannad Majeed, Wijdan Abd-al-Wahab, Mousa M. Marbut
A Cross-Sectional study that includes an assessment of the relation of the physiological and immunological factors among postmenopausal women with osteoporosis and heart diseases who attended Samarra General Hospital in Salah AL-Din Governorate .The study started from January 2022 to November 2022 on a study population whose ages ranged from 45-70 years, their total number is 100 women, 25 of whom are healthy who are considered as a control group, and 75 of them are represented by groups of patients that were distributed into three main groups: 25 women with heart disease only include myocardial infarction and 25 women with osteoporosis only and 25 women with heart disease and osteoporosis .Blood samples were collected from patients and healthy subjects and then serum separated for testing. The present study was designed to obtain more clarification of some hormonal changes in women patients with osteoporosis and heart diseases. It find out the role of some hormonal parameters Calcitonin(CT) , Parathyroid (PTH), and Estrogen ( E 2 ) in the serum of women patients with osteoporosis and heart diseases. The result of hormonal parameters include: Calcitonin, Estrogen showed significantly decreased (P≤0.05) in groups of osteoporosis, Heart disease, and osteoporosis with heart disease in comparison with control group. Parathyroid showed a significant increase (P≤0.05) in groups of osteoporosis, heart disease, and osteoporosis with heart disease in comparison with the control group. To investigate the physiological relationship between hormonal parameters,
{"title":"Estimation of The Levels of Hormonal Parameters in Patients with Osteoporosis and Heart Diseases in Samarra City","authors":"Muhannad Majeed, Wijdan Abd-al-Wahab, Mousa M. Marbut","doi":"10.21608/eajbsc.2023.330065","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.330065","url":null,"abstract":"A Cross-Sectional study that includes an assessment of the relation of the physiological and immunological factors among postmenopausal women with osteoporosis and heart diseases who attended Samarra General Hospital in Salah AL-Din Governorate .The study started from January 2022 to November 2022 on a study population whose ages ranged from 45-70 years, their total number is 100 women, 25 of whom are healthy who are considered as a control group, and 75 of them are represented by groups of patients that were distributed into three main groups: 25 women with heart disease only include myocardial infarction and 25 women with osteoporosis only and 25 women with heart disease and osteoporosis .Blood samples were collected from patients and healthy subjects and then serum separated for testing. The present study was designed to obtain more clarification of some hormonal changes in women patients with osteoporosis and heart diseases. It find out the role of some hormonal parameters Calcitonin(CT) , Parathyroid (PTH), and Estrogen ( E 2 ) in the serum of women patients with osteoporosis and heart diseases. The result of hormonal parameters include: Calcitonin, Estrogen showed significantly decreased (P≤0.05) in groups of osteoporosis, Heart disease, and osteoporosis with heart disease in comparison with control group. Parathyroid showed a significant increase (P≤0.05) in groups of osteoporosis, heart disease, and osteoporosis with heart disease in comparison with the control group. To investigate the physiological relationship between hormonal parameters,","PeriodicalId":505538,"journal":{"name":"Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology","volume":"46 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139178936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-13DOI: 10.21608/eajbsc.2023.329312
Amira Ayad, Ashraf Bakry Abdel Razik, Eman Hussein, Entesar Taha, Samir Ibrahim, S. Elateek
----------------------
----------------------
{"title":"Isolation and Transformation Mi gene Using Chitosan Nanoparticle Into Cucumber to Resist Root-Knot Nematode","authors":"Amira Ayad, Ashraf Bakry Abdel Razik, Eman Hussein, Entesar Taha, Samir Ibrahim, S. Elateek","doi":"10.21608/eajbsc.2023.329312","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.329312","url":null,"abstract":"----------------------","PeriodicalId":505538,"journal":{"name":"Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology","volume":"37 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139181833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-13DOI: 10.21608/eajbsc.2023.329310
Zaid Neamah, Omar bdul Rasheed, Alyaa Kareem
Purpose: A case-control study was conducted to evaluate the role of protencarponyls and glycemic biomarkers in type two diabetic patients with proliferative diabetic retinopathy (PDR) .Materials and Methods: a case-control study includes a comparison between 3 groups, (40 healthy persons ) as a control compared with (40 type-2 diabetic patients without proliferative retinopathy) and (40 diabetic patients with proliferative retinopathy) serum PC were determined with ELISA while glycemic biomarkers FBS, HbA1c was determined by spectrophotometry method ( autoanlyser technique) . Result : PC serum level and FBS, HbA1c statistically significantly increased among the study groups, the highest level in PDR patients when compared with control groups and T2M Patients without RP. Conclusion : Protein carbonyls are increased significantly in both T2DM without PDR and PDR patients compared with healthy people ( control ).FBS and HbA1c decreased significantly in both T2DM without PDR and PDR patients compared with healthy people ( control ).
{"title":"Assessment of Serum Protein Carbonyls and Glycemic Biomarkers in Patients with Type 2 Diabetic Proliferative Retinopathy","authors":"Zaid Neamah, Omar bdul Rasheed, Alyaa Kareem","doi":"10.21608/eajbsc.2023.329310","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.329310","url":null,"abstract":"Purpose: A case-control study was conducted to evaluate the role of protencarponyls and glycemic biomarkers in type two diabetic patients with proliferative diabetic retinopathy (PDR) .Materials and Methods: a case-control study includes a comparison between 3 groups, (40 healthy persons ) as a control compared with (40 type-2 diabetic patients without proliferative retinopathy) and (40 diabetic patients with proliferative retinopathy) serum PC were determined with ELISA while glycemic biomarkers FBS, HbA1c was determined by spectrophotometry method ( autoanlyser technique) . Result : PC serum level and FBS, HbA1c statistically significantly increased among the study groups, the highest level in PDR patients when compared with control groups and T2M Patients without RP. Conclusion : Protein carbonyls are increased significantly in both T2DM without PDR and PDR patients compared with healthy people ( control ).FBS and HbA1c decreased significantly in both T2DM without PDR and PDR patients compared with healthy people ( control ).","PeriodicalId":505538,"journal":{"name":"Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology","volume":"191 1-2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139180960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-12DOI: 10.21608/eajbsc.2023.329305
Nada Obaid
----------------------
----------------------
{"title":"Biochemical Study of the Influence of FSH, LH, and PRL Hormones in Infertile Female","authors":"Nada Obaid","doi":"10.21608/eajbsc.2023.329305","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.329305","url":null,"abstract":"----------------------","PeriodicalId":505538,"journal":{"name":"Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology","volume":"13 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139182530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-08DOI: 10.21608/eajbsc.2023.328553
Rasha Ebiya, Marwa Hassen
glucocorticoids such as azithromycin and dexamethasone. The study was designed to demonstrate the cardiotoxic consequences of anti-COVID-19 drugs and to clarify the protective role and mechanisms of different dietary natural extracts. Methods Forty-eight rats were divided into eight groups; Control, groups II-VI received 30 mg/kg azithromycin, 30 mg/kg dexamethasone and anti-COVID-19 protocol (30 mg /kg azithromycin, 30 mg/kg dexamethasone, 6.7 mg/kg vitamin C and 0.26 mg /kg zinc) orally for fourteen days, groups V-VIII received co-treatment of anti-COVID-19 protocol plus orally administration of 7.5 mg/kg Arabic gum, 4 ml/kg Nigella sativa oil, 83 µmol /kg nano-quercetin, and 500 mg/kg Thymus vulgaris extract, respectively for 14 days. Results anti COVID-19 drugs showed significant elevation in cardiac enzymes, malondialdehyde, nuclear factor-kappa B and interleukin-1 Beta besides a decrease in superoxide dismutase level. In addition, significant upregulation in expression levels of tumor necrosis factor-alpha, caspase-3 genes and alpha-smooth muscle actin in myocardial cells. However Arabic gum, Nigella sativa oil, nano-quercetin, and Thymus vulgaris extract co-treatments significantly improved these alterations and attenuated the expression of caspase-3, TNF-α genes and α-SMA protein. Conclusion: combined treatment with the examined dietary natural extracts especially nano quercetin established ameliorative effects against cardiotoxicity induced by anti-COVID-19 drugs through anti-inflammatory and anti-apoptotic effects.
{"title":"Protective Role of Nano-Quercetin and Different Natural Extracts against Cardiotoxicity Induced by Glucocorticoids (Anti-COVID-19 Drugs): Molecular and Biochemical Studies","authors":"Rasha Ebiya, Marwa Hassen","doi":"10.21608/eajbsc.2023.328553","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.328553","url":null,"abstract":"glucocorticoids such as azithromycin and dexamethasone. The study was designed to demonstrate the cardiotoxic consequences of anti-COVID-19 drugs and to clarify the protective role and mechanisms of different dietary natural extracts. Methods Forty-eight rats were divided into eight groups; Control, groups II-VI received 30 mg/kg azithromycin, 30 mg/kg dexamethasone and anti-COVID-19 protocol (30 mg /kg azithromycin, 30 mg/kg dexamethasone, 6.7 mg/kg vitamin C and 0.26 mg /kg zinc) orally for fourteen days, groups V-VIII received co-treatment of anti-COVID-19 protocol plus orally administration of 7.5 mg/kg Arabic gum, 4 ml/kg Nigella sativa oil, 83 µmol /kg nano-quercetin, and 500 mg/kg Thymus vulgaris extract, respectively for 14 days. Results anti COVID-19 drugs showed significant elevation in cardiac enzymes, malondialdehyde, nuclear factor-kappa B and interleukin-1 Beta besides a decrease in superoxide dismutase level. In addition, significant upregulation in expression levels of tumor necrosis factor-alpha, caspase-3 genes and alpha-smooth muscle actin in myocardial cells. However Arabic gum, Nigella sativa oil, nano-quercetin, and Thymus vulgaris extract co-treatments significantly improved these alterations and attenuated the expression of caspase-3, TNF-α genes and α-SMA protein. Conclusion: combined treatment with the examined dietary natural extracts especially nano quercetin established ameliorative effects against cardiotoxicity induced by anti-COVID-19 drugs through anti-inflammatory and anti-apoptotic effects.","PeriodicalId":505538,"journal":{"name":"Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology","volume":"28 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139185269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-07DOI: 10.21608/eajbsc.2023.328457
Haneen Alkaales, Shifaa Ibrahim
pathology of AD reveals neuronal inflammation and degeneration following amyloid accumulation. The aim of this research is to study the relationship between AD & the level of some proteins like alpha1-anti chymotrypsin, high sensitive C-reactive protein and 1 interlukin-6 in the blood of participants. Patients, included in this study, are 130 one complaining of AD, they were divided into two groups according to their age. while 80 normal people are involved in this study as a control group. The serum of all patients and normal subjects were taken for detection of the level of alpha-1-anti chymotrypsin, high sensitive C-reactive protein and interlukin-6.
从 AD 的病理学角度看，淀粉样蛋白积累后会导致神经元炎症和退化。这项研究的目的是研究注意力缺失症与参与者血液中一些蛋白质水平（如α1-抗糜蛋白酶、高敏感C反应蛋白和1 interlukin-6）之间的关系。参与本研究的患者中，有 130 人主诉患有注意力缺失症，他们根据年龄被分为两组，80 名正常人作为对照组。所有患者和正常人的血清均用于检测α-1-抗糜蛋白酶、高敏C反应蛋白和interlukin-6的水平。
{"title":"Alpha 1- Anti-chymotrypsin and Other Inflammatory Factors As Biomarkers for Alzheimer's Disease","authors":"Haneen Alkaales, Shifaa Ibrahim","doi":"10.21608/eajbsc.2023.328457","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.328457","url":null,"abstract":"pathology of AD reveals neuronal inflammation and degeneration following amyloid accumulation. The aim of this research is to study the relationship between AD & the level of some proteins like alpha1-anti chymotrypsin, high sensitive C-reactive protein and 1 interlukin-6 in the blood of participants. Patients, included in this study, are 130 one complaining of AD, they were divided into two groups according to their age. while 80 normal people are involved in this study as a control group. The serum of all patients and normal subjects were taken for detection of the level of alpha-1-anti chymotrypsin, high sensitive C-reactive protein and interlukin-6.","PeriodicalId":505538,"journal":{"name":"Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139185536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-05DOI: 10.21608/eajbsc.2023.328306
Jasim Awad, W. Abd-alwahab, Omar Al-Obaidi
This study aimed to indicate the levels of body mass index (BMI), thyroglobulin levels, and interleukin 1 beta among a group of patients women with hyperthyroidism. Samples were collected (60 patients) and 30 healthy women who were considered as a control group in the city of Samarra after confirming that they had hyperthyroidism . The results of the study showed a significant decrease in body mass index (BMI) (P ≤ 0.05), as the affected group suffered from a decrease in weight compared to the control group. The results of the (TG) and (IL-1β) tests also showed the presence of a significant increase at a significant level (P≤0.05) in the values of the hyperthyroidism group when compared with the control group. It is clear from the results of the study that there is an effect of the disease on the body mass index, and that an increase in the levels of both (TG) and (IL-1β) may indicate an immune influence on the progression of the disease.
{"title":"Estimation of the Body Mass Index (BMI), Thyroglobulin, and Interleukin 1 Beta of Hyperthyroidism Patients in Samarra City.","authors":"Jasim Awad, W. Abd-alwahab, Omar Al-Obaidi","doi":"10.21608/eajbsc.2023.328306","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.328306","url":null,"abstract":"This study aimed to indicate the levels of body mass index (BMI), thyroglobulin levels, and interleukin 1 beta among a group of patients women with hyperthyroidism. Samples were collected (60 patients) and 30 healthy women who were considered as a control group in the city of Samarra after confirming that they had hyperthyroidism . The results of the study showed a significant decrease in body mass index (BMI) (P ≤ 0.05), as the affected group suffered from a decrease in weight compared to the control group. The results of the (TG) and (IL-1β) tests also showed the presence of a significant increase at a significant level (P≤0.05) in the values of the hyperthyroidism group when compared with the control group. It is clear from the results of the study that there is an effect of the disease on the body mass index, and that an increase in the levels of both (TG) and (IL-1β) may indicate an immune influence on the progression of the disease.","PeriodicalId":505538,"journal":{"name":"Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139186524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：