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Correlation Between Long non-coding RNA SOX2OT rs9839776 C>T Polymorphism and Unexplained Recurrent Miscarriages 长非编码 RNA SOX2OT rs9839776 C>T 多态性与不明原因复发性流产的相关性
Pub Date : 2024-03-22 DOI: 10.21608/eajbsc.2024.346276
Nermeen Abd Ellatif, Sara Agwa, Neveen Ashaat, Mervat Elgendy
Recurrent miscarriage (RM) is a severe pregnancy complication that results in the loss of two or more spontaneous pregnancies. RM has several complex reasons. Advances in genetics, immunology, and cell biology have strongly connected non-coding RNAs (ncRNAs) to recurrent miscarriages. NcRNAs regulate placental trophoblast cell processes, which affect trophoblast development, migration, and invagination; they also have a role in breast and ovarian cancer. As a result, their abnormal expression may contribute to the progression of RM. Several investigations have found a connection between RM and genetic polymorphisms that regulate cell migration. Variations in the long non-coding RNA (lncRNA) SOX2OT gene have been associated with a variety of cancer-related illnesses, particularly colorectal cancer, breast cancer, and cancer of the digestive tract. According to a recent study, the long non-coding SOX2OT rs9839776 CT raises the risk of RM. In this review, we explain the existing evidence supporting a relationship between the LncRNA SOX2OT rs9839776 polymorphisms and recurrent miscarriages.
复发性流产(RM)是一种严重的妊娠并发症,会导致两次或两次以上的自然妊娠流产。复发性流产有几个复杂的原因。遗传学、免疫学和细胞生物学的进步将非编码 RNA(ncRNA)与复发性流产紧密联系在一起。NcRNAs 可调控胎盘滋养层细胞的过程,从而影响滋养层细胞的发育、迁移和内陷;它们还在乳腺癌和卵巢癌中发挥作用。因此,它们的异常表达可能会导致胎盘早剥。多项研究发现,RM 与调节细胞迁移的基因多态性有关。长非编码 RNA(lncRNA)SOX2OT 基因的变异与多种癌症相关疾病有关,尤其是结肠直肠癌、乳腺癌和消化道癌症。最近的一项研究发现,长非编码 SOX2OT rs9839776 CT 会增加 RM 的患病风险。在这篇综述中,我们将解释支持 LncRNA SOX2OT rs9839776 多态性与复发性流产之间关系的现有证据。
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引用次数: 0
Probiotics Benefits, Potential Limitations and Risks 益生菌的益处、潜在局限性和风险
Pub Date : 2024-03-10 DOI: 10.21608/eajbsc.2024.344590
Marwa Yousry Mohamed
Probiotics are different types of friendly types of yeasts or bacteria that improve the health of humans as well as animals
益生菌是不同种类的友好型酵母或细菌,能改善人类和动物的健康状况
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引用次数: 0
Physicochemical Properties and Fatty Acids Composition of Moringa Seed Oil Compared with Olive Oil 辣木籽油与橄榄油的理化性质和脂肪酸组成比较
Pub Date : 2024-03-08 DOI: 10.21608/eajbsc.2024.344273
Somia Ajab, A. Nour, Abdulazeem Nour, Jama Abdulgadir, M. Akhtar
The study aimed to examine the physicochemical properties of moringa seeds and assess the oil extracted from the seeds. The seeds were collected from Eldamazine in the Blue Nile state and Alsamrab north of Khartoum. The oil extracted using hexane, the color of oil examined using a Lovibond tintometer, showed red and yellow colors (0.02, 3.9) for moringa and (2.3, 31.9) for olive oil respectively. Viscosity, density, and refractive index are (23.81, 0.90, 1.472 cp) for moringa oil and (73.5, 0.91, 1.551 cp) for olive oil, respectively. Chemical characteristics of moringa and olive are free fatty acid, peroxide value, iodine value, and saponification value (0.19%, 0.49 mg O 2 /kg/oil 63.5 mg 1/kg/oil, 81.55 mg/ kg /oil, 172 mg KOH / kg oil). GLC was used to detect the fatty acid composition of moringa oil which are Palmitoleic acid (0.1860%), Palmitic acid (3.248%), Linoleic acid (0.0690%), Oleic acid (71.57%), Linolenic acid (6.725%), Stearic acid (7.127%), Arachidic acid (0.9820%), Gadoleic acid (3.842%), Behnic acid (5.973 %) and Arachidonic acid (0.2320 %). Moringa oil contained a high content of tocopherol (257 mg liter).
这项研究旨在检查辣木籽的理化特性,并评估从种子中提取的油。种子采集自青尼罗州的 Eldamazine 和喀土穆北部的 Alsamrab。用正己烷萃取的油,用洛维邦色度计检测油的颜色,红辣木籽的颜色为红色,黄辣木籽的颜色为黄色(0.02,3.9),橄榄油的颜色为红色,黄辣木籽的颜色为黄色(2.3,31.9)。辣木油的粘度、密度和折射率分别为(23.81、0.90、1.472 cp),橄榄油为(73.5、0.91、1.551 cp)。辣木油和橄榄油的化学特性包括游离脂肪酸、过氧化值、碘值和皂化值(0.19%、0.49 毫克 O 2 /千克/油、63.5 毫克 1 /千克/油、81.55 毫克/千克/油、172 毫克 KOH /千克油)。采用 GLC 法检测辣木油的脂肪酸组成:棕榈油酸(0.1860%)、棕榈酸(3.248%)、亚油酸(0.0690%)、油酸(71.57%)、亚麻酸(6.725%)、硬脂酸(7.127%)、花生四烯酸(0.9820%)、钆酸(3.842%)、贝壳杉酸(5.973%)和花生四烯酸(0.2320%)。辣木油含有大量生育酚(257 毫克升)。
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引用次数: 0
Measuring Some Vital Indicators in The Liver of People Without Breakfast Compared to The Control Group 与对照组相比,测量不吃早餐者肝脏中的一些重要指标
Pub Date : 2024-03-07 DOI: 10.21608/eajbsc.2024.344117
Fatima Al Khafaji, Reah Al-Ghazali
, your body will provide glucose and insulin. Glucose is the easiest atom for your body to diversify and use as a prebiotic, so it will be picked from a vital source of your body's energy . The findings demonstrated that, as compared to the control group, there was no discernible variation in the LDL level in those who skipped breakfast. The findings also demonstrated a statistically significant variation in HDL levels between those who skipped breakfast and the control group. The outcome showed that those who skipped breakfast had significantly lower haemoglobin levels "P < 0.05" than those in the control group. The outcome also showed that those who skipped breakfast had significantly lower platelet, red blood cell, and white blood cell counts "P < 0.05" than those in the control group. Additionally, the results showed that those who skipped breakfast had significantly lower AST and ALT levels "P < 0.05" than those in the control group. Based on the study findings, we draw the conclusion that eating natural food at regular intervals has a noticeable physiological impact on those who skip breakfast in comparison to the control group, which is what caused harm to the liver and other bodily organs' levels and activities.
您的身体会提供葡萄糖和胰岛素。葡萄糖是人体最容易多样化并用作益生元的原子,因此它将从人体能量的重要来源中被提取出来。研究结果表明,与对照组相比,不吃早餐者的低密度脂蛋白水平没有明显变化。研究结果还表明,不吃早餐的人与对照组相比,高密度脂蛋白水平的变化具有统计学意义。结果显示,不吃早餐者的血红蛋白水平明显低于对照组,"P < 0.05"。结果还显示,不吃早餐者的血小板、红细胞和白细胞计数明显低于对照组,"P < 0.05"。此外,结果还显示,不吃早餐者的谷草转氨酶和谷丙转氨酶水平明显低于对照组,"P < 0.05"。根据研究结果,我们得出结论:与对照组相比,不吃早餐的人在生理上会受到明显的影响,从而对肝脏和其他身体器官的水平和活动造成伤害。
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引用次数: 0
Commonest Position of the Vermiform Appendix among Sudanese: Cadaveric study 苏丹人蚓部盲肠的最常见位置:尸体研究
Pub Date : 2024-02-29 DOI: 10.21608/eajbsc.2024.342943
Elghazaly A. Elghazaly
errors. Several studies have shed light on this topic in different populations using different methods, but still, the commonest position of Vermiform Appendix (VA) is a subject of debate among researchers, whether in living individuals or cadavers. The current study aims to determine the commonest position of VA to provide a complete understanding of anatomical variations in both genders, using dissection. 122 bodies (92 males and 30 females) were dissected in a mortuary in 10 Sudanese medical schools, between January and September 2022, using Cunningham’s dissection method. The dissection was evaluated for various anatomical locations of the free end of the VA in both genders. The most common position of the VA in both genders was (40.2%) retrocaecal followed by (23.9%) pelvic. The incidence of retrocaecal position in both genders was about the same, while pelvic was greater in males. The commonest location of VA in Sudanese was retrocecal followed by pelvic. No statistically significant association between males and females with the position of the appendix in dissected cadavers. Cadaveric dissection is the best method for detecting the different positions of the VA, it gives wide scope for follow up its free end.
错误。已有多项研究采用不同方法在不同人群中揭示了这一主题,但无论是活人还是尸体,蝶形盲肠(VA)的最常见位置仍是研究人员争论的主题。目前的研究旨在通过解剖确定蚓部盲肠的最常见位置,从而全面了解两性的解剖变异。2022 年 1 月至 9 月期间,在苏丹 10 所医学院的停尸房,采用坎宁安解剖法解剖了 122 具尸体(92 男 30 女)。在解剖过程中,对男女尸体的VA游离端的不同解剖位置进行了评估。男女两性最常见的 VA 位置是(40.2%)盲肠后,其次是(23.9%)骨盆。盲肠后位置在男女两性中的发生率大致相同,而盆腔位置在男性中的发生率更高。苏丹人最常见的 VA 位置是盲肠后,其次是盆腔。在解剖的尸体中,男性和女性阑尾的位置没有明显的统计学关联。尸体解剖是检测盲肠不同位置的最佳方法,它为追踪盲肠游离端提供了广阔的空间。
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引用次数: 0
The Outcome of Diagnostic Coronary Angiography Regarding Patient Adherence to Routine Bed Rest Protocol at Ahmed Gasim Cardiac Center/Sudan 在苏丹艾哈迈德-加西姆心脏中心进行的冠状动脉血管造影诊断结果与患者遵守常规卧床休息协议的关系
Pub Date : 2024-02-21 DOI: 10.21608/eajbsc.2024.342306
Zeinab Omer
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引用次数: 0
Exploration of the Pathogenic Potential of Mutations Incurred in VP4 and VP7 Proteins of the Rotavirus Strain from Saudi Arabia Based on A Molecular Evolutionary Model 基于分子进化模型探讨沙特阿拉伯轮状病毒株 VP4 和 VP7 蛋白变异的致病潜力
Pub Date : 2024-02-14 DOI: 10.21608/eajbsc.2024.340634
Mohammad Izhari
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引用次数: 0
Cytogenetic and Molecular Abnormalities in Unexplained Infertility among Egyptian Couples with Special Referencing on Chromosomal Abnormalities 埃及夫妇不明原因不孕症的细胞遗传学和分子异常,特别是染色体异常
Pub Date : 2024-02-14 DOI: 10.21608/eajbsc.2024.340635
Eman Abd Elaziz, Neveen Ashaat, Sara Agwa, Ahmed Elnagar
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引用次数: 0
Cytogenetic and Molecular Abnormalities in Unexplained Infertility among Egyptian Couples with Special Referencing on Chromosomal Abnormalities 埃及夫妇不明原因不孕症的细胞遗传学和分子异常,特别是染色体异常
Pub Date : 2024-02-14 DOI: 10.21608/eajbsc.2024.340635
Eman Abd Elaziz, Neveen Ashaat, Sara Agwa, Ahmed Elnagar
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引用次数: 0
Exploration of the Pathogenic Potential of Mutations Incurred in VP4 and VP7 Proteins of the Rotavirus Strain from Saudi Arabia Based on A Molecular Evolutionary Model 基于分子进化模型探讨沙特阿拉伯轮状病毒株 VP4 和 VP7 蛋白变异的致病潜力
Pub Date : 2024-02-14 DOI: 10.21608/eajbsc.2024.340634
Mohammad Izhari
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引用次数: 0
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Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology
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