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Percutaneous sclerotherapy with gelified ethanol of low-flow vascular malformations of the head and neck region: preliminary results. 凝胶化乙醇经皮硬化治疗头颈部低流量血管畸形:初步结果。
IF 2.1 4区 医学 Q2 Medicine Pub Date : 2019-10-25 DOI: 10.5152/dir.2019.18542
A. Ierardi, G. Colletti, P. Biondetti, M. Dessy, G. Carrafiello
PURPOSEEvaluation of safety and efficacy of percutaneous sclerotherapy using gelified ethanol in patients with low-flow malformations.METHODSA retrospective study was performed, analyzing treatment and outcome data of 6 patients that presented with 7 low-flow malformations (LF-Ms) (3 lymphatic and 3 venous). Median diameter of LF-Ms was 6 cm (iqr 4.5-8.5 cm). Data regarding pain, functional and/or cosmetic issues were assessed. Diagnosis was performed clinically and confirmed Doppler Ultrasound, while extension of disease was assessed by Magnetic Resonance Imaging (MRI). Percutaneous puncture was performed with 23G needle directly or with ultrasound guidance. All the LF-Ms were treated with gelified ethanol injection. The median volume injected per treatment session resulted 4.4 mL.RESULTSTechnical and clinical success were obtained in all cases. No recurrences were registered during a median follow up of 17 months (iqr 12-19 months). Among the 6 patients, 83% of the patients had complete relief (5/6) and the other showed improvement of symptoms. The median VAS score was 7 (iqr 6-7.5) before and 0 (iqr 0-0) after treatment. All patients had functional and aesthetic improvement (100%). Four patients (66.7%) had a very good acceptance and two patients (33.3%) a good acceptance. No major complications neither systemic side effects were observed.CONCLUSIONGelified ethanol may be considered easy to handle, well-tolerated, safe and effective in the short-term follow up. Longer follow up efficacy is mandatory for further conclusions.
目的评价凝胶化乙醇经皮硬化治疗低血流畸形的安全性和有效性。方法回顾性分析6例低流量畸形(LF-Ms)患者(3例淋巴和3例静脉)的治疗和预后资料。LF-Ms的中位直径为6 cm(直径4.5-8.5 cm)。评估有关疼痛、功能和/或外观问题的数据。临床诊断和多普勒超声确诊,同时通过磁共振成像(MRI)评估疾病的扩展。经皮穿刺采用23G针直接穿刺或超声引导。所有LF-Ms均用凝胶化乙醇注射液处理。每次治疗的中位注射量为4.4 ml。结果所有病例均获得了技术和临床成功。在中位随访17个月(12-19个月)期间无复发记录。6例患者中,83%的患者完全缓解(5/6),其余患者症状改善。治疗前VAS评分中位数为7分(iqr 6-7.5),治疗后为0分(iqr 0-0)。所有患者的功能和美观均有改善(100%)。极好接受4例(66.7%),良好接受2例(33.3%)。无主要并发症及全身副作用。结论经纯化的乙醇在短期随访中操作简便、耐受性好、安全有效。更长的随访疗效是进一步结论的必要条件。
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引用次数: 8
Calcific tendinitis: intramuscular and intraosseous migration. 钙化性肌腱炎:肌肉内和骨内迁移。
IF 2.1 4区 医学 Q2 Medicine Pub Date : 2019-10-25 DOI: 10.5152/DIR.2019.18593
C. Kalaycı, E. Kızılkaya
Calcific tendinitis is a well-documented and extensively studied disease in the literature. Intramuscular and intraosseous migration are rare complications, which may present diagnostic challenges. This pictorial essay illustrates the imaging findings of these complications. Considering that neoplastic processes and infectious diseases are included in the differential diagnosis, recognizing the imaging findings of these complications is of critical importance.
钙化性肌腱炎是一种文献记载广泛的疾病。肌内和骨内迁移是罕见的并发症,可能会带来诊断挑战。这篇图片文章说明了这些并发症的影像学表现。考虑到肿瘤过程和感染性疾病包括在鉴别诊断中,认识这些并发症的影像学表现至关重要。
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引用次数: 40
Percutaneous transgastric pancreatic-duct drainage for pancreaticojejunal leak after pancreaticoduodenectomy. 经皮经胃胰管引流治疗胰十二指肠切除术后胰空肠漏。
IF 2.1 4区 医学 Q2 Medicine Pub Date : 2019-10-25 DOI: 10.5152/DIR.2019.19038
M. Kamo, R. Miyazawa, Tomoya Nisiyama, Kenji Nakamura, Kunihiro Yagihashi
Pancreaticojejunal anastomotic leakage is one of the severe complications after pancreaticoduodenectomy and is often difficult to manage. A 64-year-old man status post pancreaticoduodenectomy had the gastroduodenal artery stump bleeding caused by the pancreaticojejunal anastomotic leakage, successfully treated by placing a covered stent. To control the leakage, subsequent percutaneous transgastric pancreatic duct puncture was performed under fluoroscopic guidance, targeting a surgically placed pancreaticojejunal internal drainage catheter. A 5 F catheter with side holes was inserted into the main pancreatic duct, the tip of which was placed in the anastomosed jejunum. The leak was successfully treated using this catheter. Percutaneous transgastric pancreatic duct drainage might be a useful and feasible option to resolve the condition.
胰空肠吻合口瘘是胰十二指肠切除术后的严重并发症之一,往往难以处理。一例64岁男性患者在胰十二指肠切除术后因胰空肠吻合口漏引起胃十二指肠动脉残端出血,经置放有盖支架成功治疗。为了控制渗漏,随后在透视引导下经皮经胃胰管穿刺,目标是手术放置胰空肠内引流管。将带侧孔的5f导管插入主胰管,导管尖端置于吻合的空肠内。使用该导管成功地处理了泄漏。经皮经胃胰管引流可能是一种有效可行的治疗方法。
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引用次数: 2
Retrieval of floating clot in the internal carotid artery: extracranial SAVE technique (eSAVE). 颈内动脉浮块的回收:颅外SAVE技术(eSAVE)。
IF 2.1 4区 医学 Q2 Medicine Pub Date : 2019-09-01 DOI: 10.5152/dir.2019.19093
M. Psychogios, V. Maus
Acutely ruptured atherosclerotic plaques with adjacent floating clot within the internal carotid artery in patients suffering from extra-/intracranial tandem lesions are often treated with stent-assisted balloon angioplasty. We present a strategy to retrieve the extracranial thrombus using the "stent retriever assisted vacuum-locked extraction" (SAVE) method, which initially was described for the intracranial vasculature. The extracranial SAVE (eSAVE) method could be an additional tool for the treatment of acute tandem lesions.
患有颅内外串联病变的患者,颈内动脉内急性破裂的动脉粥样硬化斑块和邻近的漂浮凝块通常采用支架辅助球囊血管成形术进行治疗。我们提出了一种使用“支架回收器辅助真空锁定提取”(SAVE)方法回收颅外血栓的策略,该方法最初用于颅内血管系统。颅外SAVE(eSAVE)方法可能是治疗急性串联病变的额外工具。
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引用次数: 2
Comparison of low-dose CT with CT/CT Fluoroscopy guidance in percutaneous sacral and supra-acetabular cementoplasty. 低剂量CT与CT/CT透视引导下经皮骶骨和髋臼上骨水泥成形术的比较。
IF 2.1 4区 医学 Q2 Medicine Pub Date : 2019-09-01 DOI: 10.5152/dir.2019.18362
Veer A Shah, T. Hillen, J. Jennings
PURPOSEPercutaneous cementoplasty is a minimally invasive treatment modality for painful osteoporotic and pathologic sacral and supra-acetabular iliac fractures. This study compares the use of low-dose CT guidance with CT/CT fluoroscopy in sacral and supra-acetabular cementoplasty.METHODSA retrospective review of patients who had undergone sacral or supra-acetabular cementoplasty was performed with patients grouped by use of CT/CT Fluoroscopy or low-dose CT guidance during the procedure. Parameters evaluated included type of fracture, laterality of lesions, pain scores, pain medication use, imaging parameters, procedure time, dose length product, effective dose, cement volume, and complications.RESULTSThere were 17 patients identified who underwent cementoplasty utilizing dual CT/CT Fluoroscopy, while 13 patients had their procedures performed with low-dose CT. There was a statistically significant decrease in radiation dose in the low-dose CT group (1481 mGy-cm) compared to the CT/CT Fluoroscopy group (2809mGy-cm) (P = 0.013). There was a significant decrease in procedure time with low-dose CT for bilateral lesions (P = 0.016). There was no significant difference between groups in complication rate (P = 0.999). Non-clinically significant cement extravasation occurred in two patients (10%) in the CT/CT Fluoroscopy group and in one patient (8%) in the low-dose CT group (P = 0.999). There was a significant decrease in pain scores compared to baseline on the Visual Analogue Scale in both groups at 1 week (low-dose CT P = 0.002, CT/CTF P = 0.008) and 1 month post-procedure (low dose CT P = 0.014, CT/CTF P = 0.004), but no difference between groups at 1 day (P = 0.196), 1 week (P = 0.368), or 1 month (P = 0.514).CONCLUSIONSacral and supra-acetabular cementoplasties can be performed safely and precisely using low dose multiple-acquisition CT guidance while providing significant radiation dose reduction with no difference in extravasation rates, post-procedural pain reduction and complications compared to CT/CT Fluoroscopy.
目的经皮牙骨质成形术是一种微创治疗骨质疏松和病理性骶骨和髋臼上髂骨骨折的方法。本研究比较了低剂量CT引导与CT/CT透视在骶骨和髋臼上牙骨质成形术中的应用。方法对接受骶骨或髋臼上牙骨质成形术的患者进行回顾性分析,并在手术过程中使用CT/CT荧光镜或低剂量CT引导对患者进行分组。评估的参数包括骨折类型、病变偏侧性、疼痛评分、疼痛药物使用、成像参数、手术时间、剂量-长度乘积、有效剂量、水泥体积和并发症。结果17例患者采用双CT/CT荧光镜进行了牙骨质成形术,13例患者采用低剂量CT进行了手术。与CT/CT荧光镜检查组(2809mGycm)相比,低剂量CT组(1481mGycm)的辐射剂量在统计学上显著降低(P=0.013)。低剂量CT对双侧病变的手术时间显著缩短(P=0.016)。两组并发症发生率无显著差异(P=0.099)CT/CT荧光镜组有两名患者(10%)发生外渗,低剂量CT组有一名患者(8%)发生外溢(P=0.999)。两组在1周(低剂量CT P=0.002,CT/CTF P=0.008)和术后1个月(低剂量CTP=0.014,但在第1天(P=0.196)、第1周(P=0.368)或第1个月(P=0.514),各组之间没有差异。结论使用低剂量多次采集CT引导可以安全、准确地进行髋臼和髋臼上牙骨质形成,同时显著降低辐射剂量,外渗率没有差异,与CT/CT荧光镜检查相比,术后疼痛减轻和并发症。
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引用次数: 3
Treatment of metastatic gastric adenocarcinoma with image guided high-dose-rate, interstitial brachytherapy as second line or salvage therapy. 影像引导下高剂量间质近距离放射治疗转移性胃腺癌的二线或补救性治疗。
IF 2.1 4区 医学 Q2 Medicine Pub Date : 2019-09-01 DOI: 10.5152/dir.2019.18390
J. Omari, R. Drewes, Max Othmer, P. Hass, M. Pech, M. Powerski
PURPOSETo evaluate the safety and efficacy of image guided high-dose-rate interstitial brachytherapy (IBT) concerning the treatment of patients with hepatic, lymphatic and pancreatic metastases originating from gastric cancer - an entity rarely surgically treatable with curative intent.METHODSTwelve patients with a cumulative number of 36 metastases (liver: 29, pancreatic: 2, lymph nodes: 5) from histologically proven gastric adenocarcinoma received treatment with IBT between 2010 and 2016 and were retrospectively analyzed. Every patient underwent palliative chemotherapy prior to the IBT procedure. IBT employs a temporarily, intratumorally placed 192iridium source in a single fraction with the goal of tumor cell eradication. Efficacy was assessed clinically and by acquisition of CT/MRI every three months.RESULTSLocal tumor control (LTC) was achieved in 32 (89%) of all treated metastases. Four lesions showed a local recurrence after 7 months. Lesion sizes varied from 9 to 102 mm with a median of 20 mm. The median progression free survival was 6.6 months (range 1.8-46.8 months). The median overall survival was 11.4 months (range 5-47 months). One patient suffered a major complication following IBT - hepatic hematoma and abscess (Common Terminology Criteria for Adverse Events grade 3), successfully dealt with by transcutaneous drainage.CONCLUSIONIBT is an overall safe procedure, which facilitates high rates of local tumor control in treatment of metastatic gastric adenocarcinoma. Compared to surgical metastasectomy, similar overall survival rates could be achieved in our patient collective after IBT application.
目的评估图像引导高剂量率间质近距离放射治疗(IBT)治疗源自癌症的肝、淋巴和胰腺转移患者的安全性和有效性,这种肿瘤很少通过手术治疗。方法在2010年至2016年间,经组织学证实的胃腺癌累计转移36例(肝脏:29例,胰腺:2例,淋巴结:5例)的患者接受了IBT治疗,并进行了回顾性分析。每位患者在IBT手术前都接受了姑息性化疗。IBT采用肿瘤内临时放置的192铱源作为单一组分,目的是根除肿瘤细胞。疗效通过每三个月采集一次CT/MRI进行临床评估。结果32例(89%)转移瘤患者获得了局部肿瘤控制(LTC)。4个病灶在7个月后出现局部复发。病变大小从9到102毫米不等,中位数为20毫米。中位无进展生存期为6.6个月(1.8-46.8个月)。中位总生存期为11.4个月(5-47个月)。一名患者在IBT后出现主要并发症——肝血肿和脓肿(不良事件通用术语标准3级),经皮引流成功治疗。结论IBT是一种总体安全的治疗方法,有助于提高转移性胃腺癌的局部肿瘤控制率。与外科转移切除术相比,应用IBT后,我们的患者集体可以获得相似的总生存率。
{"title":"Treatment of metastatic gastric adenocarcinoma with image guided high-dose-rate, interstitial brachytherapy as second line or salvage therapy.","authors":"J. Omari, R. Drewes, Max Othmer, P. Hass, M. Pech, M. Powerski","doi":"10.5152/dir.2019.18390","DOIUrl":"https://doi.org/10.5152/dir.2019.18390","url":null,"abstract":"PURPOSE\u0000To evaluate the safety and efficacy of image guided high-dose-rate interstitial brachytherapy (IBT) concerning the treatment of patients with hepatic, lymphatic and pancreatic metastases originating from gastric cancer - an entity rarely surgically treatable with curative intent.\u0000\u0000\u0000METHODS\u0000Twelve patients with a cumulative number of 36 metastases (liver: 29, pancreatic: 2, lymph nodes: 5) from histologically proven gastric adenocarcinoma received treatment with IBT between 2010 and 2016 and were retrospectively analyzed. Every patient underwent palliative chemotherapy prior to the IBT procedure. IBT employs a temporarily, intratumorally placed 192iridium source in a single fraction with the goal of tumor cell eradication. Efficacy was assessed clinically and by acquisition of CT/MRI every three months.\u0000\u0000\u0000RESULTS\u0000Local tumor control (LTC) was achieved in 32 (89%) of all treated metastases. Four lesions showed a local recurrence after 7 months. Lesion sizes varied from 9 to 102 mm with a median of 20 mm. The median progression free survival was 6.6 months (range 1.8-46.8 months). The median overall survival was 11.4 months (range 5-47 months). One patient suffered a major complication following IBT - hepatic hematoma and abscess (Common Terminology Criteria for Adverse Events grade 3), successfully dealt with by transcutaneous drainage.\u0000\u0000\u0000CONCLUSION\u0000IBT is an overall safe procedure, which facilitates high rates of local tumor control in treatment of metastatic gastric adenocarcinoma. Compared to surgical metastasectomy, similar overall survival rates could be achieved in our patient collective after IBT application.","PeriodicalId":50582,"journal":{"name":"Diagnostic and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5152/dir.2019.18390","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48514254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Operator learning curve for transradial liver cancer embolization: implications for the initiation of a transradial access program. 经桡动脉肝癌栓塞术的操作人员学习曲线:对经桡动脉栓塞程序启动的影响。
IF 2.1 4区 医学 Q2 Medicine Pub Date : 2019-09-01 DOI: 10.5152/dir.2019.18437
R. Iezzi, A. Posa, B. Merlino, M. Pompili, E. Annicchiarico, E. Rodolfino, M. Basso, A. Cassano, A. Gasbarrini, R. Manfredi
PURPOSETo analyze transradial approach (TRA) learning curve on patients undergoing hepatic chemoembolization, investigating the relationship between procedural volumes and various benchmarks of procedural success.METHODSWe enrolled sixty consecutive patients who received two unilobar hepatic chemoembolization within a 4-week interval performed by a single interventional radiologist, highly-trained in conventional transfemoral procedures (TFA), but without any previous practical experience in TRA procedures and with a preliminary 2-days theoretical training only. We divided the study population, prospectively consecutively random-enrolled, into 3 groups: A (case 1 to 20), B (case 21 to 40), and C (case 41 to 60), using all TFA procedures performed by the same operator in the same series of patients as the control group. Primary endpoint was to analyze the relationship between TRA procedure operator experience and benchmarks of procedural success, to define the optimal procedural learning curve.RESULTSTechnical success was obtained in all patients, with a cross-over rate (radial to femoral access) of 0%. An association between incremental TRA operator experience (in terms of performed procedures) and decrease of preparation, puncture, fluoroscopy, and total examination times was observed. Similarly, inverse associations between incremental TRA operator experience and contrast medium (CM) volumes (P < 0.001) and radiation dose (RD) values (in terms of RAK - Reference Air Kerma) (P < 0.001) were also observed. Compared to TFA, CM volumes and RD values were significantly higher only in group A (1-20). Procedure success remained high in all TRA groups and no significant association between TRA incremental experience and post-procedural outcomes was found. Higher post-procedural complaints at the access route and more limitations in performing basic activities were recorded in TFA vs TRA patients (P < 0.001).CONCLUSIONTRA catheterizations can be safely performed in patients treated for liver cancer embolization after a relatively short training in controlled conditions and with a better performance in comparison with TFA. Operator proficiency improves with greated TRA experience, with a threshold needed to overcome the learning curve represented by about 20 procedures.
目的分析肝化学栓塞患者的经桡动脉入路(TRA)学习曲线,研究手术量与手术成功的各种基准之间的关系。方法我们招募了60名连续的患者,他们在4周内接受了两次单叶肝化学栓塞治疗,由一名受过传统经股动脉手术(TFA)高度训练的介入放射科医生进行,但之前没有任何TRA手术的实践经验,只接受了为期2天的初步理论训练。我们将前瞻性连续随机入选的研究人群分为3组:A组(病例1至20)、B组(病例21至40)和C组(病例41至60),使用同一操作员在同一系列患者中进行的所有TFA程序作为对照组。主要终点是分析TRA程序操作员经验与程序成功基准之间的关系,以确定最佳程序学习曲线。结果所有患者均获得了技术上的成功,交叉率(桡骨至股骨通路)为0%。观察到TRA操作员经验的增加(就所执行的程序而言)与准备、穿刺、荧光透视和总检查时间的减少之间的关联。同样,TRA操作员的增量经验与造影剂(CM)体积(P<0.001)和辐射剂量(RD)值(根据RAK-参考空气Kerma)(P<001)之间也存在负相关。与TFA相比,只有A组(1-20)的CM体积和RD值显著更高。所有TRA组的手术成功率仍然很高,TRA增量经验与术后结果之间没有发现显著关联。TFA与TRA患者在进入途径上的术后投诉较高,基本活动受限较多(P<0.001)。结论接受癌症栓塞治疗的患者在受控条件下经过相对较短的训练后,可以安全地进行TRA插管,与TFA相比,其表现更好。操作员的熟练程度随着TRA经验的丰富而提高,需要一个阈值来克服由大约20个过程表示的学习曲线。
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引用次数: 13
Laser angioplasty of peripheral arteries: basic principles, current clinical studies, and future directions. 外周动脉激光血管成形术:基本原理、当前临床研究和未来方向。
IF 2.1 4区 医学 Q2 Medicine Pub Date : 2019-09-01 DOI: 10.5152/dir.2019.18515
F. Stanek
Percutaneous transluminal angioplasty (PTA) is a routine procedure for the treatment of peripheral arterial disease. However, its main limitation is late restenosis occurring at a 1-year rate of 6%-60%. Restenosis arises from injury to the arterial wall including overstretching, compression and rupture of the atherosclerotic plaque during balloon inflation. It is hypothesized that better long-term angioplasty results are observed if atherosclerotic plaques are removed rather than compressed and fractured. Laser angioplasty is one method to remove atherosclerotic plaques. We discuss the principles of lasers, physical properties of laser light, history of laser angioplasty and effects of laser radiation on tissues. Large clinical studies using laser angioplasty are critically assessed. In comparison to conventional PTA, there are some advantages of laser angioplasty: easier passage through chronic and calcified occlusions and according to some studies, better short- and medium-term results regarding limb salvage and management of in-stent restenoses. The main drawback of laser angioplasty is that current laser catheters are not able to create a sufficiently wide channel in the occlusion, meaning that adjunctive balloon dilatation is still required. Thus, long-term data may be misleading. Basic and applied research should continue to focus on enlargement of plaque ablation.
经皮腔内血管成形术(PTA)是治疗外周动脉疾病的常规方法。然而,它的主要局限性是1年再狭窄发生率为6%-60%。再狭窄是由动脉壁损伤引起的,包括球囊膨胀时动脉粥样硬化斑块的过度拉伸、压迫和破裂。假设如果动脉粥样硬化斑块被移除,而不是被压缩和断裂,可以观察到更好的长期血管成形术结果。激光血管成形术是去除动脉粥样硬化斑块的一种方法。我们讨论了激光的原理,激光光的物理特性,激光血管成形术的历史和激光辐射对组织的影响。使用激光血管成形术的大型临床研究被严格评估。与传统的PTA相比,激光血管成形术有一些优点:更容易通过慢性和钙化闭塞,根据一些研究,在肢体保留和支架内再狭窄治疗方面有更好的中短期效果。激光血管成形术的主要缺点是目前的激光导管不能在闭塞处形成足够宽的通道,这意味着仍然需要辅助球囊扩张。因此,长期数据可能具有误导性。基础和应用研究应继续关注斑块消融的扩大。
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引用次数: 7
Avoiding peripheral nerve injury in arterial interventions. 动脉介入治疗中避免外周神经损伤。
IF 2.1 4区 医学 Q2 Medicine Pub Date : 2019-09-01 DOI: 10.5152/dir.2019.18296
F. Kuo, Jonathan K. Park, Kira Chow, Alice Chen, M. Walsworth
Although peripheral nerve injuries secondary to angiography and endovascular interventions are uncommon and usually are not permanent, they can result in significant functional impairment. Most arteries used in access for angiography and endovascular therapies lie in close proximity to a nerve. The nerve may be injured by needle puncture, or by compression from hematoma, pseudoaneurysm, hemostasis devices, or by manual compression with incidence in literature ranging from as low as 0.04% for femoral access in a large retrospective study to 9% for brachial and axillary access. Given the increasing frequency of endovascular arterial procedures and the increasing use of nontraditional access points, it is important that the interventionalist have a working knowledge of peripheral nerve anatomy and function as it relates to relevant arteria access sites to avoid injury.
尽管血管造影术和血管内介入术后继发的外周神经损伤并不常见,通常也不是永久性的,但它们可能会导致严重的功能损伤。用于血管造影术和血管内治疗的大多数动脉都靠近神经。神经可能因针刺、血肿压迫、假性动脉瘤、止血装置或手动压迫而受伤,文献中股骨入路的发生率低至0.04%,肱动脉和腋下入路的发病率为9%。鉴于血管内动脉手术的频率越来越高,非传统接入点的使用也越来越多,重要的是,介入医生必须具备外周神经解剖和功能的工作知识,因为它与相关的动脉接入点有关,以避免损伤。
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引用次数: 19
Long-term follow-up of transjugular intrahepatic portosystemic shunt (TIPS) with stent-graft. 经颈静脉肝内门体分流术(TIPS)支架植入术的长期随访。
IF 2.1 4区 医学 Q2 Medicine Pub Date : 2019-09-01 DOI: 10.5152/dir.2019.18416
M. Perelló, Javier Pueyo Mur, M. Vives, Juan Manuel Martinez Riutort, Asuncion Pastor Artigues, C. Garcia, Maria Lucia Bonet Vidal, Ana Escarda Gelabet, M. Garau
PURPOSEWe aimed to retrospectively evaluate the long-term clinical and patency results after the placement of transjugular intrahepatic portosystemic shunts (TIPS) using stent-graft. Many studies show the clinical results and the patency follow-up of TIPS with stent-graft in the short and medium term. However, few studies show long-term results.METHODSBetween 2002 and 2016, TIPS with stent-grafts were placed in 132 patients. The median age was 59.5 years. The median Model for End-stage Liver Disease (MELD) score was 13, and 71% were Child-Pugh B. Indications for TIPS were bleeding (83%) and ascites or hydrothorax (17%). The technical and clinical success rates were calculated, as were the rates of patency, survival and complications. The median follow-up period was 43 months.RESULTSThe technical success rate was 98%, and the clinical success rates were 85% in patients with indication for bleeding and 95% in patients with indication for ascites or hydrothorax. Primary patency did not decrease from 66% after 6 years (95% confidence interval [CI], 56.2%-75.8%) primary assisted patency remained stable at 87% after 6 years (95% CI, 77.2%-96.8%) and secondary patency did not decrease from 98% after 4 years (95% CI, 95.1%-100%). The median overall survival was 42.8 months (95% CI, 33.8-51.8 months). A total of 54 patients suffered some type of complication, minor (28 patients) or major (26 patients), during the follow-up.CONCLUSIONThe clinical success rate was high. The choice of the maximum initial limit of portosystemic gradient and the diameter of the post-TIPS shunt, together with the number of shunt reductions, are important to be able to compare results between publications. In our study, the patency rates did not decrease after 6 years; hence, long-term follow-up of these patients may not be necessary.
目的:我们旨在回顾性评估使用支架移植物放置经颈静脉肝内门体分流术(TIPS)后的长期临床和通畅性结果。许多研究显示了TIPS支架移植物在中短期内的临床结果和通畅性随访。然而,很少有研究显示长期的结果。方法2002年至2016年间,对132名患者进行了TIPS支架植入术。中位年龄为59.5岁。终末期肝病模型(MELD)评分的中位数为13,71%为Child-Pugh B。TIPS的适应症为出血(83%)和腹水或胸腔积液(17%)。计算技术和临床成功率,以及通畅率、生存率和并发症。中位随访期为43个月。结果出血指征患者的技术成功率为98%,临床成功率为85%,腹水或胸水指征患者为95%。6年后,一期通畅率没有从66%下降(95%置信区间[CI],56.2%-75.8%),6年后一期辅助通畅率稳定在87%(95%CI,77.2%-96.8%);4年后二期通畅率也没有从98%下降(95%可信区间,95.1%-100%)。中位总生存期为42.8个月(95%可信范围,33.8-51.8个月)。在随访中,共有54例患者出现了某种类型的并发症,包括轻微并发症(28例)或严重并发症(26例)。结论临床成功率高。门体梯度的最大初始极限和TIPS后分流的直径的选择,以及分流减少的次数,对于能够比较出版物之间的结果非常重要。在我们的研究中,6年后通畅率没有下降;因此,可能没有必要对这些患者进行长期随访。
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引用次数: 18
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Diagnostic and Interventional Radiology
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