Clinical Imaging最新文献_第4页

Optimizing ChatGPT-4's radiology performance with scale-invariant feature transform and advanced prompt engineering 利用尺度不变特征变换和先进提示工程优化ChatGPT-4的放射学性能

IF 1.8 4区医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Imaging

Pub Date : 2024-11-28 DOI: 10.1016/j.clinimag.2024.110368

Sultan Alam, Abdul Rahman, Shahab Saquib Sohail

引用次数: 0

Impact factors and publication times of original scientific research in radiology journals 放射学期刊原创科研成果的影响因子及发表次数

IF 1.8 4区医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Imaging

Pub Date : 2024-11-26 DOI: 10.1016/j.clinimag.2024.110370

Lucy Y. Lei , Osher N.Y. Lee , Charlotte J. Yong-Hing , Nicolas Murray , Ismail T. Ali , Adnan M. Sheikh , Harneet Cheema , Faisal Khosa

Purpose

The time from article submission to publication in peer-reviewed scientific journals is variable and can be prolonged, which slows the dissemination of research and can influence the academic progress of authors. This study evaluated the publication times for articles in radiology journals, in particular the relationship between turnaround times and journal impact factors (IFs).

Methods

Bibliometric data was obtained from Journal Citation Reports to conduct a comparative analysis of radiology journals against those in other disciplines of clinical medicine using highest IF, median IF, cited half-life, immediacy index, and number of journals. Journals from various radiology subcategories were further examined to assess IF trends over time. The Pearson correlation coefficient was used to identify any statistically significant relationships between IF and other variables.

Results

Among 28 medical disciplines, there was a significant positive correlation of 0.63 between the number of journals and the highest journal IF of a given discipline. Among 135 radiology journals categorized into 12 subcategories, there was a similar significant correlation of 0.64. For high-ranking radiology journals, the median time from submission to publication online was 22.7 weeks [IQR = 9.3] and median time from submission to publication in print was 37.9 weeks [IQR = 7.1]. The former time interval showed a positive correlation of 0.58 with journal IF at p < 0.05.

Conclusion

There is wide variation in the time from submission to publication in radiology journals. Authors can expect a longer turnaround time when publishing in higher-impact journals.

从文章提交到在同行评议的科学期刊上发表的时间是可变的，可以延长，这减缓了研究的传播，并可能影响作者的学术进步。本研究评估了放射学期刊文章的发表时间，特别是周转时间与期刊影响因子（if）之间的关系。方法从《Journal Citation Reports》中获取文献计量学数据，采用最高影响因子、中位影响因子、被引半衰期、即时性指数和期刊数量等指标对放射学期刊与其他临床医学学科期刊进行比较分析。我们进一步研究了来自不同放射学亚类的期刊，以评估IF随时间的趋势。使用Pearson相关系数来确定IF与其他变量之间是否存在统计学上显著的关系。结果28个医学学科中，期刊数量与该学科最高期刊影响因子呈显著正相关（0.63）；在被分为12个亚类的135种放射学期刊中，存在相似的显著相关，为0.64。高水平放射学期刊从投稿到在线发表的中位时间为22.7周[IQR = 9.3]，从投稿到印刷出版的中位时间为37.9周[IQR = 7.1]。前一个时间间隔与期刊IF呈0.58的正相关（p <）；0.05.结论放射学期刊从投稿到发表的时间差异较大。在高影响力期刊上发表文章时，作者可以期待更长的周转时间。

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引用次数: 0

Diversity, inclusivity and traceability of mammography datasets used in development of Artificial Intelligence technologies: a systematic review 人工智能技术开发中乳房x光检查数据集的多样性、包容性和可追溯性：系统综述

IF 1.8 4区医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Imaging

Pub Date : 2024-11-26 DOI: 10.1016/j.clinimag.2024.110369

Elinor Laws , Joanne Palmer , Joseph Alderman , Ojasvi Sharma , Victoria Ngai , Thomas Salisbury , Gulmeena Hussain , Sumiya Ahmed , Gagandeep Sachdeva , Sonam Vadera , Bilal Mateen , Rubeta Matin , Stephanie Kuku , Melanie Calvert , Jacqui Gath , Darren Treanor , Melissa McCradden , Maxine Mackintosh , Judy Gichoya , Hari Trivedi , Xiaoxuan Liu

Purpose

There are many radiological datasets for breast cancer, some which have supported the development of AI medical devices for breast cancer screening and image classification. This review aims to identify mammography datasets (including digitised screen film mammography, 2D digital mammography and digital breast tomosynthesis) used in the development of AI technologies and present their characteristics, including their transparency of documentation, content, populations included and accessibility.

Materials and methods

MEDLINE and Google Dataset searches identified studies describing AI technology development and referencing breast imaging datasets up to June 2024. The characteristics of each dataset are summarised. In particular, the accompanying documentation was reviewed with a focus on diversity and inclusion of populations represented within each dataset.

Results

254 datasets were referenced in the literature search, 190 were privately held, 36 had barriers which prevented access, and 28 were accessible. Most datasets originated from Europe, East Asia and North America. There was poor reporting of individuals' attributes: 32 (12 %) datasets reported race or ethnicity; 76 (30 %) reported female/male categories with only one dataset explicitly defining whether these categories represented sex or gender attributes.

Conclusion

Through this review, we demonstrate gaps in the data landscape for mammography, highlighting poor representation globally. To ensure datasets in breast imaging have maximum utility for researchers, their characteristics should be documented and limitations of datasets, such as their representativeness of populations and settings, should inform scientific efforts to translate data-driven insights into technologies and discoveries.

目的乳腺癌放射学数据集很多，其中一些数据集支持了用于乳腺癌筛查和图像分类的人工智能医疗设备的开发。本综述旨在确定用于人工智能技术开发的乳房x光检查数据集（包括数字化屏幕胶片乳房x光检查、2D数字乳房x光检查和数字乳房断层合成），并介绍其特征，包括文档的透明度、内容、包括的人群和可及性。材料和方法medline和谷歌数据集搜索确定了描述人工智能技术发展的研究，并参考了截至2024年6月的乳房成像数据集。总结了每个数据集的特征。特别地，对随附的文件进行了审查，重点关注每个数据集中所代表的人口的多样性和包容性。结果共检索到254个数据集，其中私有数据集190个，存在访问障碍数据集36个，可访问数据集28个。大多数数据集来自欧洲、东亚和北美。对个人属性的报告很差：32个（12%）数据集报告了种族或民族；76个（30%）报告了女性/男性类别，只有一个数据集明确定义了这些类别是否代表性别或性别属性。通过这篇综述，我们展示了乳房x光检查数据格局的差距，突出了全球代表性不足。为了确保乳腺成像中的数据集对研究人员有最大的效用，它们的特征应该被记录下来，数据集的局限性，比如它们对人群和环境的代表性，应该为科学工作提供信息，将数据驱动的见解转化为技术和发现。

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引用次数: 0

Complicated appendicitis in the pediatric patient: interventional perspectives 小儿复杂阑尾炎：介入性观点

IF 1.8 4区医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Imaging

Pub Date : 2024-11-26 DOI: 10.1016/j.clinimag.2024.110371

Ronnie W. AlRamahi , Andrew Woerner , Hassan Rizvi , Eric J. Monroe

This pictorial review provides a comprehensive visual and textual overview of interventional radiology approaches in treating complicated appendicitis and other abdominal abscesses in children. This review discusses the incidence and complications associated with appendicitis in pediatric patients, highlighting the role of percutaneous drainage in managing appendicitis with abscesses. We present common mimics of intra-abdominal abscesses from other diseases such as tubo-ovarian abscesses, inflammatory bowel disease, and lymphomatous bowel involvement, emphasizing imaging pitfalls that can mimic appendiceal abscesses. The review also covers interventional radiology considerations, including antibiotic indications, local anesthesia considerations for children, the comparison between percutaneous and endocavitary approaches, and the roles of fibrinolytics are discussed here. Detailed discussions on catheter selection and insertion techniques, such as Seldinger and trocar, are provided along with post-procedure management strategies. These include drain maintenance, navigating drain associated complications, and determining when to remove the drain. Through high-quality images and concise descriptions, we illustrate procedural intricacies and clinical scenarios encountered in practice, offering a valuable educational resource for clinicians managing pediatric abscesses.

这篇图片综述提供了一个全面的视觉和文字概述介入放射学方法治疗复杂的阑尾炎和其他腹部脓肿的儿童。本文综述了小儿阑尾炎的发病率和并发症，强调了经皮引流术在阑尾炎脓肿治疗中的作用。我们介绍了其他疾病如输卵管卵巢脓肿、炎症性肠病和肠淋巴瘤累及的常见腹内脓肿的模拟，强调了可以模拟阑尾脓肿的成像陷阱。本文还讨论了介入放射学方面的考虑，包括抗生素适应症、儿童局部麻醉的考虑、经皮和腔内入路的比较以及纤维蛋白溶解剂的作用。详细讨论了导管的选择和插入技术，如Seldinger和套管针，以及术后管理策略。这些措施包括排水管维护、排水管相关并发症的处理，以及决定何时拆除排水管。通过高质量的图像和简洁的描述，我们阐述了在实践中遇到的程序复杂性和临床场景，为临床医生管理儿科脓肿提供了宝贵的教育资源。

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引用次数: 0

Opportunistic screening of osteoporosis by CT scan compared to DXA: A systematic review and meta-analysis 与DXA相比，CT扫描对骨质疏松症的机会性筛查：一项系统回顾和荟萃分析

IF 1.8 4区医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Imaging

Pub Date : 2024-11-26 DOI: 10.1016/j.clinimag.2024.110372

Seyedeh Zahra Mousavi , Reza Moshfeghinia , Hossein Molavi Vardanjani , Mohammad Reza Sasani

The efficacy of opportunistic osteoporosis screening with computed tomography (CT) scans obtained for other indications has not yet been implemented by the current guidelines. We aimed to compile available evidence on the efficacy of osteoporosis screening with CT scans obtained for other indications compared with dual X-ray absorptiometry (DXA).

Studies comparing the diagnostic performance of the CT scan with the DXA published before 2023 were retrieved. We conducted a bias assessment using the Newcastle-Ottawa Scale for cross-sectional studies. Correlation coefficients (CC), area under the curve (AUC), sensitivity, and specificity of the CT scans compared with the DXA were meta-analyzed with random effects modeling. 41 studies fulfilled the inclusion/exclusion criteria. The included studies reported weak to very strong CC (0.35 to 0.95) and low to high accuracy for opportunistic osteoporosis screening with CT scans. The meta-analysis showed a moderate pooled CC of 0.59 (95 % CI: 0.53–0.64, P-value<0.001), and a relatively high AUC of 0.81 (95 % CI: 0.78–0.84, P-value<0.001). Subgroup analysis based on age and menopausal status did not show significant between-group differences. Significantly higher accuracy measures were estimated for CT scans of the proximal femur compared to other anatomic regions (CC: 0.70, 95 % CI: 0.57–0.82; AUC: 0.79, 95 % CI: 0.72–0.87), North American cases (CC: 0.66, 95 % CI: 0.52–0.80; AUC: 0.82, 95 % CI: 0.82–0.83), and populations with a higher percentage of women (CC: 0.60, 95 % CI: 0.52–0.69; AUC: 0.86, 95 % CI: 0.83–0.89). We observed a moderate performance of opportunistic osteoporosis screening with CT scans obtained for other indications.

利用计算机断层扫描（CT）筛查其他适应症的机会性骨质疏松症的有效性尚未在现行指南中实施。我们的目的是收集与双x线吸收仪（DXA）相比，用CT扫描筛查骨质疏松症的有效性的现有证据。检索了2023年前发表的比较CT扫描与DXA诊断性能的研究。我们使用纽卡斯尔-渥太华量表对横断面研究进行了偏倚评估。与DXA相比，CT扫描的相关系数（CC）、曲线下面积（AUC）、敏感性和特异性采用随机效应建模进行meta分析。41项研究符合纳入/排除标准。纳入的研究报告了CT扫描的机会性骨质疏松筛查的弱至强CC（0.35至0.95）和低至高准确率。荟萃分析显示，中度合并CC为0.59 (95% CI: 0.53-0.64， p值<；0.001)，相对较高的AUC为0.81 （95% CI: 0.78-0.84， p值<；0.001）。基于年龄和绝经状态的亚组分析没有显示组间的显著差异。与其他解剖区域相比，估计股骨近端CT扫描的准确度显着更高(CC: 0.70, 95% CI: 0.57-0.82；AUC: 0.79, 95% CI: 0.72-0.87)，北美病例(CC: 0.66, 95% CI: 0.52-0.80；AUC: 0.82, 95% CI: 0.82 - 0.83)，以及女性比例较高的人群(CC: 0.60, 95% CI: 0.52-0.69；Auc: 0.86, 95% ci: 0.83-0.89)。我们观察到，通过CT扫描获得的其他适应症的机会性骨质疏松症筛查表现中等。

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引用次数: 0

Inter-observer and intra-observer agreement of bone reporting and data system (Bone-RADS) in the interpretation of bone tumors on computed tomography 骨报告和数据系统（Bone-RADS）在解读计算机断层扫描骨肿瘤方面的观察者间和观察者内一致性

IF 1.8 4区医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Imaging

Pub Date : 2024-11-22 DOI: 10.1016/j.clinimag.2024.110367

Zainab Ahmad Ramadan (Zainab A. Ramadan), Amel Helmy Elmorsy (Amel Helmy), Saher Ebrahim Taman (Saher Taman), Fatmaelzahraa Abdelfattah Denewar (FA Denewar)

Objective

To assess inter-observer & intra-observer agreement of the American College of Radiology (ACR) bone reporting and data system (Bone-RADS) in the interpretation of bone tumors on computed tomography (CT).

Methods

This retrospective study included 273 bone tumors 184 (67.4 %) benign and 89 (32.6 %) malignant. Two blinded radiologists independently reviewed the CT images to assess the defined CT features of bone lesions and assign a bone-RADS category. A third observer reviewed the CT images twice with one month interval and reported the specified CT features and final bone-RADS category for bone lesions. Inter-observer and intra-observer agreement of bone-RADS were analyzed.

Results

There was almost perfect inter-observer agreement between the two reviewers for all defined variables as well as bone-RADS categories (Kappa = 92.2 %). Overall intra-observer agreement was also perfect for all defined CT features and bone RADS categories with higher percentage than inter-observer one (κ = 98.3 %).

Conclusion

Bone-RADS is an effective clinical tool for practicing radiologists in the risk assessment and management of bone tumors with perfect agreement among observers. To our knowledge, no studies have been conducted for assessing reliability or validity of the recent ACR Bone-RADS using CT. Hence, this study could serve as a cornerstone for further upcoming studies to assess the reproducibility and validity of the ACR Bone-RADS.

目的评估美国放射学会（ACR）骨报告和数据系统（Bone-RADS）在解读计算机断层扫描（CT）骨肿瘤时观察者之间和观察者内部的一致性。两名双盲放射科医生独立审阅 CT 图像，评估骨病变的 CT 定义特征并划分骨-RADS 类别。第三位观察者两次审查 CT 图像，每次间隔一个月，并报告指定的 CT 特征和骨病变的最终骨-RADS 类别。分析了骨-RADS的观察者间和观察者内的一致性。结果在所有定义的变量和骨-RADS类别上，两位审查者的观察者间一致性几乎完美（Kappa = 92.2 %）。结论骨RADS是放射科医生进行骨肿瘤风险评估和管理的有效临床工具，观察者之间完全一致。据我们所知，目前还没有研究使用 CT 评估最新 ACR 骨-RADS 的可靠性或有效性。因此，本研究可作为评估 ACR 骨-RADS 可重复性和有效性的进一步研究的基石。

{"title":"Inter-observer and intra-observer agreement of bone reporting and data system (Bone-RADS) in the interpretation of bone tumors on computed tomography","authors":"Zainab Ahmad Ramadan (Zainab A. Ramadan), Amel Helmy Elmorsy (Amel Helmy), Saher Ebrahim Taman (Saher Taman), Fatmaelzahraa Abdelfattah Denewar (FA Denewar)","doi":"10.1016/j.clinimag.2024.110367","DOIUrl":"10.1016/j.clinimag.2024.110367","url":null,"abstract":"<div><h3>Objective</h3><div>To assess inter-observer & intra-observer agreement of the American College of Radiology (ACR) bone reporting and data system (Bone-RADS) in the interpretation of bone tumors on computed tomography (CT).</div></div><div><h3>Methods</h3><div>This retrospective study included 273 bone tumors 184 (67.4 %) benign and 89 (32.6 %) malignant. Two blinded radiologists independently reviewed the CT images to assess the defined CT features of bone lesions and assign a bone-RADS category. A third observer reviewed the CT images twice with one month interval and reported the specified CT features and final bone-RADS category for bone lesions. Inter-observer and intra-observer agreement of bone-RADS were analyzed.</div></div><div><h3>Results</h3><div>There was almost perfect inter-observer agreement between the two reviewers for all defined variables as well as bone-RADS categories (Kappa = 92.2 %). Overall intra-observer agreement was also perfect for all defined CT features and bone RADS categories with higher percentage than inter-observer one (κ = 98.3 %).</div></div><div><h3>Conclusion</h3><div>Bone-RADS is an effective clinical tool for practicing radiologists in the risk assessment and management of bone tumors with perfect agreement among observers. To our knowledge, no studies have been conducted for assessing reliability or validity of the recent ACR Bone-RADS using CT. Hence, this study could serve as a cornerstone for further upcoming studies to assess the reproducibility and validity of the ACR Bone-RADS.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"117 ","pages":"Article 110367"},"PeriodicalIF":1.8,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142721758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A real-world comparison of the diagnostic performances of six different TI-RADS guidelines, including ACR-/Kwak-/K-/EU-/ATA-/C-TIRADS 对六种不同的 TI-RADS 指南（包括 ACR-/Kwak-/K-/EU-/ATA-/C-TIRADS 指南）的诊断性能进行实际比较

IF 1.8 4区医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Imaging

Pub Date : 2024-11-22 DOI: 10.1016/j.clinimag.2024.110366

Osman Melih Topcuoglu, Betul Uzunoglu , Tolga Orhan, Ekin Bora Basaran, Ayşegul Gormez, Ozgur Sarica

Purpose

To compare the diagnostic performance of six different currently available guidelines including the American College of Radiology Thyroid Imaging and Reporting Data System (ACR-TIRADS), Kwak-TIRADS, Korean TIRADS (K-TIRADS), European TIRADS (EU-TIRADS), American Thyroid Association (ATA) and Chinese TIRADS (C-TIRADS), in differentiating malignant from benign thyroid nodules (TN).

Materials and methods

In this single-center study, between January-2007 and September-2023, ultrasound (US) images of TNs that were pathologically proven either by surgery or by fine needle aspiration biopsy (FNAB), were retrospectively evaluated and categorized according to six different currently available guidelines. Area under curve (AUC), sensitivity, specificity, positive and negative predictive values (PPV and NPV, respectively) and miss rates for malignancy (MRM) were calculated for each guideline.

Results

A total of 829 TNs (n = 234 malignant and n = 595 benign) were included. AUC, sensitivity, specificity, PPV, NPV and accuracy for ACR-TIRADS were 0.786, 99.8 %, 27.1 %, 31.92 %, 99.73 % and 54.6 %, respectively; for Kwak-TIRADS 0.839, 97.8 %, 42.1 %, 36.29 %, 98.11 % and 63.1 %, respectively; for K-TIRADS 0.797, 97.6 %, 41.6 %, 36.01 %, 84.85 % and 62.8, respectively, for EU-TIRADS 0.766, 97.8 %, 35.6 %, 33.89 %, 97.92 % and 59.1 %, respectively, for ATA 0.788, 97.5 %, 49.8 %, 32.86 %, 88.16 % and 64.2 %, respectively and for C-TIRADS 0.842, 0 %, 92.8 %, 54.3 %, 39.53 %, 90.42 %, and 68.8 % respectively. MRM regarding ACR-/Kwak-/K-/EU−/ATA-/C-TIRADS were 2.2 %, 0.5 %, 2.9 %, 2.5 %, 3.3 % and 0.1 %, respectively.

Conclusion

Six different currently available TIRADS guidelines can provide effective differentiation of malignant TNs from benign ones with similar diagnostic performances. However; C-TIRADS offered the highest AUC and the lowest MRM than the other guidelines, in this series.

目的比较美国放射学会甲状腺影像和报告数据系统（ACR-TIRADS）、Kwak-TIRADS、韩国TIRADS（K-TIRADS）、欧洲TIRADS（EU-TIRADS）、美国甲状腺协会（ATA）和中国TIRADS（C-TIRADS）等六种不同的现有指南在区分恶性和良性甲状腺结节（TN）方面的诊断性能。材料和方法在这项单中心研究中，对 2007 年 1 月至 2023 年 9 月期间经手术或细针穿刺活检（FNAB）病理证实的甲状腺结节的超声（US）图像进行了回顾性评估，并根据目前可用的六种不同指南进行了分类。计算了每种指南的曲线下面积（AUC）、灵敏度、特异性、阳性和阴性预测值（分别为 PPV 和 NPV）以及恶性肿瘤漏诊率（MRM）。ACR-TIRADS 的 AUC、灵敏度、特异性、PPV、NPV 和准确度分别为 0.786、99.8 %、27.1 %、31.92 %、99.73 % 和 54.6 %；Kwak-TIRADS 分别为 0.839、97.8 %、42.1 %、36.29 %、98.11 % 和 63.1 %；K-TIRADS 分别为 0.797、97.6 %、41.6 %、36.01 %、84.分别为 0.797、97.6 %、41.6 %、36.01 %、84.85 % 和 62.8 %；EU-TIRADS 分别为 0.766、97.8 %、35.6 %、33.89 %、97.92 % 和 59.1 %；ATA 分别为 0.788、97.5 %、49.8 %、32.86 %、88.16 % 和 64.2 %；C-TIRADS 分别为 0.842、0 %、92.8 %、54.3 %、39.53 %、90.42 % 和 68.8 %。ACR-/Kwak-/K-/EU-/ATA-/C-TIRADS的MRM分别为2.2 %、0.5 %、2.9 %、2.5 %、3.3 %和0.1 %。然而，与其他指南相比，C-TIRADS 的 AUC 最高，MRM 最低。

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引用次数: 0

Role of volumetric tumor enhancement on CT in predicting overall survival in patients with unresectable pancreatic ductal adenocarcinoma CT 上肿瘤体积增强对预测不可切除胰腺导管腺癌患者总生存期的作用

IF 1.8 4区医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Imaging

Pub Date : 2024-11-20 DOI: 10.1016/j.clinimag.2024.110365

Seyedeh Panid Madani , Alireza Mohseni , Mohammad Mirza-Aghazadeh-Attari , Haneyeh Shahbazian , Shadi Afyouni , Ali Borhani , Ghazal Zandieh , Daniel Laheru , Ihab R. Kamel

Purpose

To assess the utility of volumetric tumor enhancement on CT to predict tumor treatment response and the overall survival (OS) of patients with PDAC undergoing FOLFIRINOX-based systemic chemotherapy. Additionally, we aim to explore the performance of a novel model that incorporates relevant volumetric CT-derived parameters to the established RECIST 1.1 in predicting both treatment response and OS.

Material and methods

In this retrospective single-institution study, 127 patients with PDAC who received FOLFIRINOX neoadjuvant chemotherapy between December 2012 and November 2021 were included. Manual volumetric segmentation of the single largest tumor was performed on portal venous phase images. Total and enhancing tumor volumes were calculated. Response by RECIST 1.1 was compared to response by tumor volume and enhancing tumor volume on follow-up CT.

Results

There was no association between overall survival and RECIST 1.1 (p-value = 0.284), volumetric RECIST (p-value = 0.402), and other volumetric CT variables, except for a percentage reduction in enhancing tumor volume (p-value = 0.043). Using univariate survival analysis for categorical thresholds defined by CART, the percentage change in enhancing tumor volume was associated with OS (p-value = 0.018). There was also a significant association between baseline enhancing tumor volume and OS (p-value <0.0001). Using these two categories, we defined a multivariable model associated with OS (p-value <0.0001).

Conclusion

Percentage reduction in enhancing tumor volume was related to OS in non-surgical PDAC patients treated with FOLFIRINOX chemotherapy and could potentially be incorporated into patient survival prediction models.

目的评估 CT 上肿瘤体积增强对预测接受 FOLFIRINOX 全身化疗的 PDAC 患者的肿瘤治疗反应和总生存期（OS）的实用性。此外，我们还旨在探索一种新型模型在预测治疗反应和OS方面的性能，该模型在已建立的RECIST 1.1的基础上纳入了相关的CT容积衍生参数。在门静脉相位图像上对单个最大肿瘤进行手动体积分割。计算肿瘤总体积和增强肿瘤体积。结果总生存期与RECIST 1.1（P值=0.284）、RECIST容积（P值=0.402）和其他CT容积变量之间没有关联，除了肿瘤体积增大的百分比减少（P值=0.043）。通过对 CART 定义的分类阈值进行单变量生存分析，增强肿瘤体积变化的百分比与 OS 相关（p 值 = 0.018）。基线增大肿瘤体积与 OS 之间也有明显的相关性（p 值为 0.0001）。结论在接受FOLFIRINOX化疗的非手术PDAC患者中，肿瘤体积增大的百分比与OS有关，有可能被纳入患者生存预测模型。

{"title":"Role of volumetric tumor enhancement on CT in predicting overall survival in patients with unresectable pancreatic ductal adenocarcinoma","authors":"Seyedeh Panid Madani , Alireza Mohseni , Mohammad Mirza-Aghazadeh-Attari , Haneyeh Shahbazian , Shadi Afyouni , Ali Borhani , Ghazal Zandieh , Daniel Laheru , Ihab R. Kamel","doi":"10.1016/j.clinimag.2024.110365","DOIUrl":"10.1016/j.clinimag.2024.110365","url":null,"abstract":"<div><h3>Purpose</h3><div>To assess the utility of volumetric tumor enhancement on CT to predict tumor treatment response and the overall survival (OS) of patients with PDAC undergoing FOLFIRINOX-based systemic chemotherapy. Additionally, we aim to explore the performance of a novel model that incorporates relevant volumetric CT-derived parameters to the established RECIST 1.1 in predicting both treatment response and OS.</div></div><div><h3>Material and methods</h3><div>In this retrospective single-institution study, 127 patients with PDAC who received FOLFIRINOX neoadjuvant chemotherapy between December 2012 and November 2021 were included. Manual volumetric segmentation of the single largest tumor was performed on portal venous phase images. Total and enhancing tumor volumes were calculated. Response by RECIST 1.1 was compared to response by tumor volume and enhancing tumor volume on follow-up CT.</div></div><div><h3>Results</h3><div>There was no association between overall survival and RECIST 1.1 (p-value = 0.284), volumetric RECIST (p-value = 0.402), and other volumetric CT variables, except for a percentage reduction in enhancing tumor volume (p-value = 0.043). Using univariate survival analysis for categorical thresholds defined by CART, the percentage change in enhancing tumor volume was associated with OS (p-value = 0.018). There was also a significant association between baseline enhancing tumor volume and OS (p-value <0.0001). Using these two categories, we defined a multivariable model associated with OS (p-value <0.0001).</div></div><div><h3>Conclusion</h3><div>Percentage reduction in enhancing tumor volume was related to OS in non-surgical PDAC patients treated with FOLFIRINOX chemotherapy and could potentially be incorporated into patient survival prediction models.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"117 ","pages":"Article 110365"},"PeriodicalIF":1.8,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142721757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A month-long case-based bootcamp improves subjective and objective radiology knowledge for first-year radiology residents 为期一个月的病例训练营提高了一年级放射科住院医师的主观和客观放射学知识水平

IF 1.8 4区医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Imaging

Pub Date : 2024-11-20 DOI: 10.1016/j.clinimag.2024.110361

Shaun Johnson , Nathan Amann , Shweta Ravi , Ameya Nayate , Michael Wien , Inas Mohamed , Karin Herrmann , Navid Faraji

Purpose

First-year radiology residents enter residency with varying degrees of prior knowledge regarding radiology, which can be difficult for both trainees and physician educators looking to provide instruction. Recognizing this dilemma, we propose the adoption of a blended learning model PGY-2 radiology bootcamp at the start of training to give a structured foundation of imaging concepts.

Methods

20 total PGY-2 radiology residents spanning two cohorts of 10, one from 2022 and another from 2023, were included in a 4-week blended learning-style bootcamp at the beginning of their training. Effectiveness of the implementation was assessed using subjective Likert-scale surveys and an objective knowledge-based examination.

Results

Subjective confidence in basic radiology skills significantly improved for all modalities in the combined 2022-2023 results. Objective performance on the knowledge-based examination significantly improved in both cohorts, with no significant discrepancies in baseline scores between 2022 and 2023.

Conclusions

We recommend the implementation of a flipped-classroom, blended learning-style bootcamp for PGY-2 radiology residents. Our results demonstrated both subjective and objective improvement in radiology resident confidence and clinical knowledge, in addition to an early introduction to the institutional PACS.

目的一年级放射科住院医师在进入住院医师培训阶段之前对放射学的了解程度各不相同，这对学员和希望提供指导的医生教育者来说都很困难。认识到这一困境后，我们建议在培训开始时采用混合学习模式的 PGY-2 放射学训练营，为影像学概念打下结构化基础。方法在培训开始时，20 名 PGY-2 放射学住院医师参加了为期 4 周的混合学习式训练营，这两批住院医师各 10 人，分别来自 2022 年和 2023 年。结果在 2022-2023 年的综合结果中，所有模式的放射学基本技能的主观信心都有显著提高。结论我们建议对 PGY-2 级放射学住院医师实施翻转课堂、混合学习式训练营。我们的研究结果表明，除了提前了解机构 PACS 外，放射科住院医师的主观和客观信心和临床知识都得到了提高。

{"title":"A month-long case-based bootcamp improves subjective and objective radiology knowledge for first-year radiology residents","authors":"Shaun Johnson , Nathan Amann , Shweta Ravi , Ameya Nayate , Michael Wien , Inas Mohamed , Karin Herrmann , Navid Faraji","doi":"10.1016/j.clinimag.2024.110361","DOIUrl":"10.1016/j.clinimag.2024.110361","url":null,"abstract":"<div><h3>Purpose</h3><div>First-year radiology residents enter residency with varying degrees of prior knowledge regarding radiology, which can be difficult for both trainees and physician educators looking to provide instruction. Recognizing this dilemma, we propose the adoption of a blended learning model PGY-2 radiology bootcamp at the start of training to give a structured foundation of imaging concepts.</div></div><div><h3>Methods</h3><div>20 total PGY-2 radiology residents spanning two cohorts of 10, one from 2022 and another from 2023, were included in a 4-week blended learning-style bootcamp at the beginning of their training. Effectiveness of the implementation was assessed using subjective Likert-scale surveys and an objective knowledge-based examination.</div></div><div><h3>Results</h3><div>Subjective confidence in basic radiology skills significantly improved for all modalities in the combined 2022-2023 results. Objective performance on the knowledge-based examination significantly improved in both cohorts, with no significant discrepancies in baseline scores between 2022 and 2023.</div></div><div><h3>Conclusions</h3><div>We recommend the implementation of a flipped-classroom, blended learning-style bootcamp for PGY-2 radiology residents. Our results demonstrated both subjective and objective improvement in radiology resident confidence and clinical knowledge, in addition to an early introduction to the institutional PACS.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"117 ","pages":"Article 110361"},"PeriodicalIF":1.8,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142721759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Managing career transition decisions in medicine: a commentary and review of challenges and strategies 管理医学中的职业过渡决策：对挑战和策略的评论和回顾

IF 1.8 4区医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Imaging

Pub Date : 2024-11-19 DOI: 10.1016/j.clinimag.2024.110364

Aparna Singhal

引用次数: 0