Clinical Imaging最新文献

{"title":"Dr. Eleanor Montague - Advancing the care of patients with breast cancer","authors":"Amanda L. Pomeroy , Kara Romano","doi":"10.1016/j.clinimag.2025.110418","DOIUrl":"10.1016/j.clinimag.2025.110418","url":null,"abstract":"","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"119 ","pages":"Article 110418"},"PeriodicalIF":1.8,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143071163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A model for prediction of recurrence of non-small cell lung cancer based on clinical data and CT imaging characteristics","authors":"Xinjie Yu ,&nbsp;Dengfa Yang ,&nbsp;Gang Xu ,&nbsp;Fengjuan Tian ,&nbsp;Hengfeng Shi ,&nbsp;Zongyu Xie ,&nbsp;Zhenyu Cao ,&nbsp;Jian Wang","doi":"10.1016/j.clinimag.2025.110416","DOIUrl":"10.1016/j.clinimag.2025.110416","url":null,"abstract":"<div><h3>Objectives</h3><div>To establish a model for prediction of recurrence of non-small cell lung cancer (NSCLC) based on clinical data and computed tomography (CT) imaging characteristics.</div></div><div><h3>Methods</h3><div>A total of 695 patients with surgically resected NSCLC confirmed by pathology at three centers were retrospectively investigated. 626 patients from center 1 were randomly divided into two sets in a ratio of 7:3 (training set, <em>n</em> = 438; testing set, <em>n</em> = 188), 69 patients from center 2 and 3 were assigned in the external validation set. Univariate and binary logistic regression analyses of clinical and CT imaging features determined the independent risk factors used to construct the model. The receiver-operating characteristic curve nomogram and decision curves analysis were used to evaluate the predictive ability of the model.</div></div><div><h3>Results</h3><div>The mean patient age was 63.3 ± 10.1 years, and 44.7 % (311/695) were male. The univariate and binary logistic regression analyses identified four independent risk factors (age, tumor markers, consolidation/tumor ratio, and pleural effusion), which were used to construct the prediction model. In the training set, the model had an area under the curve of 0.857, an accuracy of 71.7 %, a sensitivity of 88.1 %, and a specificity of 70.0 %; in the testing set, the respective values were 0.867, 75.5 %, 94.4 %, and 73.5 %; in the external validation set, the respective values were 0.852, 79.7 %, 83.3 %, 78.9 %.</div></div><div><h3>Conclusion</h3><div>A prediction model based on clinical data and CT imaging characteristics showed excellent efficiency in prediction of recurrence of NSCLC. Clinical use of this model could be useful for selection of appropriate treatment options.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"120 ","pages":"Article 110416"},"PeriodicalIF":1.8,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143173391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Colorectal liver metastases on gadoxetic acid-enhanced MRI: Typical characteristics decrease after chemotherapy","authors":"Denise J. van der Reijd ,&nbsp;Ezgi A. Soykan ,&nbsp;Birthe C. Heeres ,&nbsp;Doenja M.J. Lambregts ,&nbsp;Marieke A. Vollebergh ,&nbsp;Koert F.D. Kuhlmann ,&nbsp;Niels F.M. Kok ,&nbsp;Petur Snaebjornsson ,&nbsp;Regina G.H. Beets-Tan ,&nbsp;Monique Maas ,&nbsp;Elisabeth G. Klompenhouwer","doi":"10.1016/j.clinimag.2025.110417","DOIUrl":"10.1016/j.clinimag.2025.110417","url":null,"abstract":"<div><h3>Purpose</h3><div>To determine to what extent colorectal liver metastases (CRLM) display typical imaging characteristics on gadoxetic acid-enhanced magnetic resonance imaging (MRI) and what changes after chemotherapy.</div></div><div><h3>Methods</h3><div>We retrospectively identified 258 patients with a gadoxetic acid-enhanced MRI between 2015 and 2021 and pathologically proven non-mucinous adenocarcinoma CRLM. 722 unique CRLMs were analyzed: 378 CRLM in only the chemotherapy-naïve analysis; 217 in post-chemotherapy analysis; and 127 CRLM were analyzed both pre- and post-chemotherapy. The following six characteristics were defined as typical; “hypovascular”, “unenhanced T1-weighted (UE-T1W) hypointensity”, “arterial rim enhancement”, “non-enhancing during hepatobiliary phase”, “T2-weighted (T2W) mild hyperintensity”, and “diffusion restriction”.</div></div><div><h3>Results</h3><div>All six typical characteristics were found in 249/505 chemotherapy-naïve CRLM (49 %) and 87/344 post-chemotherapy CRLM (25 %). The occurrence of some typical characteristics decreased post-chemotherapy: UE-T1W hypointensity 485/505 (96 %) versus 311/336 (93 %), arterial rim enhancement 291/498 (58 %) versus 154/301 (51 %), T2W mild hyperintensity 478/505 (95 %) versus 269/338 (79 %), and diffusion restriction 435/497 (87 %) versus 200/306 (65 %). Almost all metastases showed a hypovascular appearance, both in the chemotherapy-naïve (495/504, 98 %) and post-chemotherapy group (330/331, 100 %). Additionally, all CRLM appeared non-enhancing compared to the liver in the hepatobiliary phase (100 %).</div></div><div><h3>Conclusion</h3><div>Most CRLM show various combinations of at least five typical characteristics on gadoxetic acid-enhanced MRI. Arterial rim enhancement is the least prevalent characteristic both in chemotherapy-naïve and post-chemotherapy patients. Post-chemotherapy the occurrence of typical MRI characteristics decreases, especially mild T2W hyperintensity and the presence of diffusion restriction.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"119 ","pages":"Article 110417"},"PeriodicalIF":1.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"VoxRad: Building an open-source locally-hosted radiology reporting system","authors":"Ankush Ankush","doi":"10.1016/j.clinimag.2025.110414","DOIUrl":"10.1016/j.clinimag.2025.110414","url":null,"abstract":"<div><div>VoxRad is an open-source application designed to enhance radiology reporting by leveraging generative AI. Utilizing locally hosted Automatic Speech Recognition (ASR) and Large Language Models (LLM), VoxRad enables continuous dictation, transcribing reports into standardized formats with high accuracy, efficiency, and data security. The modular design allows flexible integration of user-selected ASR and LLM models via OpenAI-compatible APIs, ensuring HIPAA compliance with secure local storage of data. Customizable template guided prompting using Chain-of-Thought like systematic processing, and specialized dictionaries further optimize report generation. VoxRad's future aims include healthcare system integration and community-driven template libraries, enhancing its utility for the medical community.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"119 ","pages":"Article 110414"},"PeriodicalIF":1.8,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of ultrasound in facial hyaluronic acid dermal filler injections – A review article","authors":"Shatha Jamal Almushayt","doi":"10.1016/j.clinimag.2025.110413","DOIUrl":"10.1016/j.clinimag.2025.110413","url":null,"abstract":"<div><div>Injectable dermal fillers have seen a remarkable rise in popularity in recent years for aesthetic enhancements, such as facial contouring and rejuvenation. Hyaluronic acid (HA)-based fillers are especially favored due to their tolerability, minimal invasiveness, and effectiveness. This review examines the applications of ultrasound in HA dermal filler procedures. A literature search was conducted from February 25 to 26, 2024, using Medline and Google Scholar to identify relevant studies on the use of ultrasound for facial HA dermal fillers. Inclusion criteria included peer-reviewed English language studies from the last decade and involving living human subjects. Eleven studies met these criteria. The findings indicate that ultrasound significantly enhances the accuracy and safety of HA filler procedures by enabling precise vascular mapping, filler detection, and complication detection and identification. By presenting evidence of reduced risks and improved outcomes, this review underscores the potential for ultrasound to become a standard tool in HA filler applications, representing an innovation and a new application for ultrasound in the field of aesthetic dermatology.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"119 ","pages":"Article 110413"},"PeriodicalIF":1.8,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of renal cell carcinoma with ablation in comparison to nephrectomy: A 5-year analysis of inpatient procedural data to evaluate utilization disparities in the United States","authors":"Tarig S. Elhakim ,&nbsp;Taha Lodhi ,&nbsp;Wilton Fidelis ,&nbsp;Allison Brea ,&nbsp;Ana Mort ,&nbsp;Maryam Mohagheghtabar ,&nbsp;Azadeh Tabari ,&nbsp;Samuel R. Davis ,&nbsp;Raul N. Uppot ,&nbsp;Ronald S. Arellano ,&nbsp;Michael Dezube ,&nbsp;Dania Daye","doi":"10.1016/j.clinimag.2025.110412","DOIUrl":"10.1016/j.clinimag.2025.110412","url":null,"abstract":"<div><h3>Purpose</h3><div>To perform a nationwide analysis of ablation compared to partial and total nephrectomy for the management of renal cell carcinoma (RCC) to evaluate utilization trends and disparities in the USA.</div></div><div><h3>Materials and methods</h3><div>The 2016–2020 National Inpatient Sample was analyzed. Using ICD-10, we identified the diagnosis of RCC then analyzed the utilization trends of ablation and nephrectomies (both partial and complete). To determine if any disparities exist, a multivariate logistic regression was performed to assess the influence of age, sex, race, income, payer, illness severity, geographical location, and hospital factors.</div></div><div><h3>Results</h3><div>From the 183,885 inpatient encounters with RCC, 3045 (1.65 %) underwent ablation, 70,080 (38.1 %) underwent partial nephrectomy, and 110,760 (60.2 %) underwent total nephrectomy. There was no significant difference in the sex between all groups. There was a statistically significant difference in the mean age of those undergoing ablation (67.30, SD = 12.05) versus those undergoing partial nephrectomy (59.27, SD = 13.26) and total nephrectomy (62.22, SD = 14.42) (OR: 1.04, 95%CI: 1.03–1.05, <em>P</em> &lt; 0.001). Compared to White patients, Hispanic and African Americans were more likely to undergo ablation versus nephrectomy (OR: 1.52, 95%CI: 1.16–1.98, <em>P</em> = 0.002 and OR: 1.65, 95%CI: 1.28–2.13, <em>P</em> &lt; 0.001, respectively). Compared to patients on private insurance, those on Medicaid and Medicare were more likely to have ablation than nephrectomy (OR: 1.85, 95%CI: 1.31–2.61, <em>P</em> &lt; 0.001, and OR: 1.62, 95%CI: 1.26–2.08, <em>P</em> &lt; 0.001, respectively). Furthermore, patients were less likely to undergo ablation than nephrectomies in 2020 compared to 2016 (OR: 0.69, 95%CI: 0.53–0.90, <em>P</em> = 0.006).</div></div><div><h3>Conclusion</h3><div>Since 2016, there has been a decreasing trend in the use of ablation for treating RCC in hospitalized patients. Those undergoing ablation tend to be older, African American, Hispanic, and insured by Medicare or Medicaid. Further research is needed to ensure equitable access for optimal treatment of RCC.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"119 ","pages":"Article 110412"},"PeriodicalIF":1.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143043255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"There is no “I” in team: Implications for academic radiology","authors":"Steven P. Rowe ,&nbsp;Jennifer A. Schroeder ,&nbsp;Linda C. Chu ,&nbsp;Elliot K. Fishman","doi":"10.1016/j.clinimag.2025.110411","DOIUrl":"10.1016/j.clinimag.2025.110411","url":null,"abstract":"<div><div>All of us must find the right balance between team science and fostering leadership with dynamic colleagues. That dichotomy was well-encapsulated in a famous exchange between basketball players Shaquille O'Neal and Kobe Bryant regarding there “being no ‘I’ in team”. In our view, there is nothing more satisfying than collaborating with a team of people and publishing impactful papers or making key discoveries. At the same time, there are innumerable instances of collaborations stumbling along and the team failing to gel in a meaningful way. Strong leaders may be very important to propagating the overall team approach. Those leaders may be acknowledging that the team is composed of individuals who all bring something to the table. In this way, a diversity of backgrounds of the individual teammates makes the team stronger. The key, of course, is to find the right team and build within that team a strong foundation. Ultimately, we need to emphasize the importance of both team science and individual excellence in our work. In this manuscript, we will emphasize that as scientific endeavor continues to become more complex, leveraging diverse teams will be increasingly important – but also that team success cannot come at the expense of the uniquely talented individual.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"119 ","pages":"Article 110411"},"PeriodicalIF":1.8,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond the ink: Marking the skin with henna through ultrasound gel","authors":"Samuel Jang ,&nbsp;Brooke E. Willborg ,&nbsp;Gina K. Hesley ,&nbsp;Nathan J. Brinkman ,&nbsp;Nho V. Tran ,&nbsp;Matthew W. Urban ,&nbsp;Christine U. Lee","doi":"10.1016/j.clinimag.2025.110410","DOIUrl":"10.1016/j.clinimag.2025.110410","url":null,"abstract":"<div><h3>Purpose</h3><div>To evaluate henna as a durable skin marker on various skin tones for sonographic targeting and to identify the shortest duration of henna application needed for practical clinical workflow.</div></div><div><h3>Materials and methods</h3><div>Prospective study applying seven henna lines through ultrasound (US) gel on the forearms of 15 healthy participants equally represented across the validated six-color bar tool. Color bar categories 1–2, 3–4, and 5–6 were designated low, moderate, and high-melanin groups, respectively. Each subsequent line was applied with staining wait-times ranging from 10 to 480 s. Serial photographs were obtained after scrubbing with chlorhexidine every 2–3 days with the number of clearly visible lines assessed by participants, by individual and consensus physician reads, and by band intensity quantification.</div></div><div><h3>Results</h3><div>Henna could be applied through US gel and the markings were resistant to chlorhexidine scrubbing. Staining wait-times for 60, 120, and 240 s resulted in visible lines for 6, 8, and 10 days (low-melanin), 5, 6, and 8 days (moderate-melanin), and 2, 3, and 4 days (high-melanin). No lines were visible on day 13 for most participants in the low or moderate-melanin groups and on day 6 on most participants in the high-melanin group. The marking intensities decreased more quickly in the moderate-melanin group compared the low-melanin group.</div></div><div><h3>Conclusion</h3><div>Henna is an effective skin marker that can be applied through US gel where short staining wait-times result in markings lasting several days. To achieve the same durability, staining wait-times are about double for high-melanin skin tones compared to low or moderate-melanin skin tones.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"119 ","pages":"Article 110410"},"PeriodicalIF":1.8,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic performance and clinical outcomes of computed tomography colonography in a sick inpatient population","authors":"Jessica T. Lovett ,&nbsp;Chenchan Huang ,&nbsp;Vinay Prabhu","doi":"10.1016/j.clinimag.2025.110401","DOIUrl":"10.1016/j.clinimag.2025.110401","url":null,"abstract":"<div><h3>Purpose</h3><div>Though prior studies have proven CTC's efficacy in outpatients, its utility in the inpatient setting has not been studied. We evaluated the efficacy of a modified CTC protocol in the inpatient setting, primarily for patients awaiting organ transplantation.</div></div><div><h3>Methods</h3><div>This retrospective study compared a group of inpatient CTCs from 2019 to 2021 and a randomly selected, age-matched 2:1 control group of outpatient CTCs. Both groups were assessed based on established criteria from literature.</div></div><div><h3>Results</h3><div>10 % (63/652) of CTCs were performed in the inpatient setting, of which 29 were excluded, yielding 34 inpatient cases. 90 % (589/652) of CTCs were performed in the outpatient setting, from which 68 randomly selected, age-matched patients were selected as controls. Significantly more (24 %, 8/34) inpatients expired due to extracolonic causes (vs. 1 %, 1/68 outpatients, <em>p</em> &lt; 0.05). 62 % (21/34) of inpatient CTCs were reported as diagnostic (vs. 74 %, 50/68 outpatient, <em>p</em> = 0.22). Significantly more inpatients (12 %, 4/34) than outpatients (1 %, 1/68) were unable to tolerate two imaging positions (<em>p</em> = 0.02). Subsequent colonoscopy was performed in 24 % (8/34) of inpatients, revealing pathologies including colonic polyps and non-bleeding ulcers. Inpatient CTCs had lower average quality scores, significant for one reviewer (<em>p</em> = 0.009–0.054). Inpatients had a larger number of segments with: &gt;25 % residual fluid (1.22–1.28 inpatients vs. 0.60–0.73 outpatients, <em>p</em> = 0.003–0.026) and inadequate fluid tagging (1.10 inpatients vs. 0.49 outpatients, <em>p</em> = 0.046–0.0501). Distention was not significantly different between groups (<em>p</em> = 0.317–0.410).</div></div><div><h3>Conclusion</h3><div>Quality of inpatient CTC was inferior to outpatient CTCs across several metrics. 24 % undergoing inpatient CTC died of extracolonic causes within 22 months, and most did not have findings warranting intervention, questioning the value of this difficult exam in this patient population. Routine CT may be sufficient to exclude large or metastatic colonic lesions precluding transplant.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"119 ","pages":"Article 110401"},"PeriodicalIF":1.8,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143043253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"4D flow cardiac magnetic resonance in pediatric congenital heart disease: Insights from over four years of clinical practice","authors":"Kerstin Lagerstrand ,&nbsp;Pär-Arne Svensson ,&nbsp;Linnea Andersson ,&nbsp;Anna Nyström ,&nbsp;Frida Dangardt ,&nbsp;Charlotte de Lange","doi":"10.1016/j.clinimag.2024.110399","DOIUrl":"10.1016/j.clinimag.2024.110399","url":null,"abstract":"<div><h3>Background</h3><div>Congenital heart diseases (CHDs) are common birth defects. This work presents over four years of clinical experience of 4D flow cardiovascular magnetic resonance (CMR), highlighting its value for pediatric CHD.</div></div><div><h3>Methods</h3><div>Children with various CHD diagnoses (<em>n</em> = 298) were examined on a 1.5 or 3 T scanner using 4D flow CMR in free breathing with respiratory compensation. The image volume was acquired in axial orientation, covering the entire heart and major vessels. Head-to-head comparisons with reference standards were systematically performed.</div></div><div><h3>Results</h3><div>4D flow CMR provided more detailed insights into complex cardiovascular conditions while maintaining a comparable level of accuracy in peak velocity, Q and Qp/Qs (<em>R</em> = 0.9–1.0) compared to conventional 2D flow CMR. The advantages of 4D flow CMR were particularly evident for valve function, stenosis, and shunt assessments. However, our findings emphasize the need for additional corrections to address partial volume (up to 180 % error in perfusion ratio) and through-plane cardiac motion effects (up to 25/10 ml error in aortic/pulmonary regurgitation volume).</div></div><div><h3>Conclusion</h3><div>Overall, 4D flow CMR proved to be a comprehensive diagnostic tool that enhanced the understanding and management of pediatric CHD, potentially changing the course of the treatment.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"119 ","pages":"Article 110399"},"PeriodicalIF":1.8,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}