Pub Date : 2026-02-01Epub Date: 2026-01-16DOI: 10.1016/j.ciresp.2025.800283
Pablo Lozano Lominchar , Paula Muñoz , Cristina Ballester , Cristobal Muñoz Casares , Daniel Díaz , Vicente Olivares-Ripoll , Patricia Marrero , Lorena Cambeiro , Irene López , Hugo Vasques , Jose Manuel Asencio , on behalf of the Spanish Society of Surgeons, the Portuguese Sarcoma Group (Society of Surgeons)
Background
Retroperitoneal sarcoma (RPS) is a rare malignancy requiring complex surgical management. While Enhanced Recovery After Surgery (ERAS®) protocols have improved outcomes in various surgical specialties, their implementation in RPS remains inconsistent.
Objective
This study aimed to evaluate current perioperative care practices for RPS surgery across Spain and Portugal, identifying gaps in protocol standardization and assessing the feasibility of consensus-based approaches.
Methods
A structured online survey was distributed to members of the Spanish and Portuguese Societies of Surgeons. The questionnaire encompassed five domains: demographics, preoperative, intraoperative, and postoperative practices, and attitudes toward perioperative consensus.
Results
Among 266 survey accesses, 37 complete responses were analyzed. Only 27% of respondents reported having a dedicated ERAS® protocol for RPS, though 89.2% employed ERAS® pathways for other surgeries. Prehabilitation elements —such as smoking cessation (21.6%), nutritional support (73%), and supervised physical therapy (37.8%)— were inconsistently applied. Intraoperatively, goal-directed fluid therapy was used by 51.4%, while 97.3% adhered to restrictive transfusion thresholds. Postoperative variability was notable in diet resumption, mobilization, and nasogastric tube use. All respondents supported the creation of an RPS-specific perioperative care consensus.
Conclusions
There is marked heterogeneity in perioperative care for RPS across Iberian centers. Standardized, evidence-based guidelines are urgently needed to improve consistency and optimize patient outcomes.
腹膜后肉瘤(RPS)是一种罕见的恶性肿瘤,需要复杂的手术治疗。虽然ERAS (Enhanced Recovery After Surgery)方案改善了各种外科专科的预后,但其在RPS中的实施仍然不一致。目的本研究旨在评估目前西班牙和葡萄牙RPS手术的围手术期护理实践,确定方案标准化方面的差距,并评估基于共识的方法的可行性。方法对西班牙和葡萄牙外科医师协会会员进行结构化的在线调查。调查问卷包括五个方面:人口统计学,术前,术中,术后实践,以及对围手术期共识的态度。结果在266条调查通道中,分析了37条完整回复。只有27%的受访者报告有专门的ERAS®RPS方案,尽管89.2%的受访者采用ERAS®途径进行其他手术。戒烟(21.6%)、营养支持(73%)和有监督的物理治疗(37.8%)等康复要素的应用不一致。术中,51.4%的患者使用目标导向的液体治疗,而97.3%的患者坚持限制性输血阈值。术后在饮食恢复、活动和鼻胃管使用方面的差异是显著的。所有的应答者都支持建立一个特定于rps的围手术期护理共识。结论伊比利亚各中心RPS围手术期护理存在明显的异质性。迫切需要标准化的、以证据为基础的指南,以提高一致性并优化患者的预后。
{"title":"Cuidados perioperatorios en la cirugía del sarcoma retroperitoneal primario: una encuesta hispano-lusa sobre prácticas actuales","authors":"Pablo Lozano Lominchar , Paula Muñoz , Cristina Ballester , Cristobal Muñoz Casares , Daniel Díaz , Vicente Olivares-Ripoll , Patricia Marrero , Lorena Cambeiro , Irene López , Hugo Vasques , Jose Manuel Asencio , on behalf of the Spanish Society of Surgeons, the Portuguese Sarcoma Group (Society of Surgeons)","doi":"10.1016/j.ciresp.2025.800283","DOIUrl":"10.1016/j.ciresp.2025.800283","url":null,"abstract":"<div><h3>Background</h3><div>Retroperitoneal sarcoma (RPS) is a rare malignancy requiring complex surgical management. While Enhanced Recovery After Surgery (ERAS®) protocols have improved outcomes in various surgical specialties, their implementation in RPS remains inconsistent.</div></div><div><h3>Objective</h3><div>This study aimed to evaluate current perioperative care practices for RPS surgery across Spain and Portugal, identifying gaps in protocol standardization and assessing the feasibility of consensus-based approaches.</div></div><div><h3>Methods</h3><div>A structured online survey was distributed to members of the Spanish and Portuguese Societies of Surgeons. The questionnaire encompassed five domains: demographics, preoperative, intraoperative, and postoperative practices, and attitudes toward perioperative consensus.</div></div><div><h3>Results</h3><div>Among 266 survey accesses, 37 complete responses were analyzed. Only 27% of respondents reported having a dedicated ERAS® protocol for RPS, though 89.2% employed ERAS® pathways for other surgeries. Prehabilitation elements —such as smoking cessation (21.6%), nutritional support (73%), and supervised physical therapy (37.8%)— were inconsistently applied. Intraoperatively, goal-directed fluid therapy was used by 51.4%, while 97.3% adhered to restrictive transfusion thresholds. Postoperative variability was notable in diet resumption, mobilization, and nasogastric tube use. All respondents supported the creation of an RPS-specific perioperative care consensus.</div></div><div><h3>Conclusions</h3><div>There is marked heterogeneity in perioperative care for RPS across Iberian centers. Standardized, evidence-based guidelines are urgently needed to improve consistency and optimize patient outcomes.</div></div>","PeriodicalId":50690,"journal":{"name":"Cirugia Espanola","volume":"104 2","pages":"Article 800283"},"PeriodicalIF":1.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145982103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01Epub Date: 2026-01-16DOI: 10.1016/j.ciresp.2025.800256
Marina Garcés Albir , Francisco García García , Isabel Mora Oliver , Elena Muñoz Forner , Luis Sabater Orti , Dimitri Dorcaratto , GRUPO 3D-PANC Integrantes Grupo 3D-PANC
Neoadjuvant chemotherapy followed by surgery represents the treatment of choice for patients with borderline and locally advanced pancreatic adenocarcinoma (PAC). Despite being the diagnostic technique of choice for PAC staging, computed tomography (CT) has very low accuracy in identifying patients who may benefit from surgical resection after neoadjuvant therapy. Consequently, the study of new image processing technologies is gaining significant importance. However, no prospective validation studies of these new technologies currently exist. The 3D-PANC study is a multicenter prospective study that will include patients with borderline or locally advanced PAC undergoing neoadjuvant chemotherapy and surgical exploration with curative intent. The objective is to compare the accuracy of the 3D-MSP (Model for Surgery Planning) model versus conventional CT for preoperative diagnosis of vascular involvement after neoadjuvant treatment (NAT) in patients with borderline or locally advanced PAC. This will be achieved by analyzing the accuracy variables of both techniques against the gold standard (surgical outcomes and histopathological analysis).
{"title":"Protocolo del estudio 3D-PANC: ¿es la tecnología de imagen en tres dimensiones superior a la tomografía computarizada para evaluar la respuesta al tratamiento neoadyuvante en los pacientes con adenocarcinoma de páncreas borderline o localmente avanzado?","authors":"Marina Garcés Albir , Francisco García García , Isabel Mora Oliver , Elena Muñoz Forner , Luis Sabater Orti , Dimitri Dorcaratto , GRUPO 3D-PANC Integrantes Grupo 3D-PANC","doi":"10.1016/j.ciresp.2025.800256","DOIUrl":"10.1016/j.ciresp.2025.800256","url":null,"abstract":"<div><div>Neoadjuvant chemotherapy followed by surgery represents the treatment of choice for patients with borderline and locally advanced pancreatic adenocarcinoma (PAC). Despite being the diagnostic technique of choice for PAC staging, computed tomography (CT) has very low accuracy in identifying patients who may benefit from surgical resection after neoadjuvant therapy. Consequently, the study of new image processing technologies is gaining significant importance. However, no prospective validation studies of these new technologies currently exist. The 3D-PANC study is a multicenter prospective study that will include patients with borderline or locally advanced PAC undergoing neoadjuvant chemotherapy and surgical exploration with curative intent. The objective is to compare the accuracy of the 3D-MSP (Model for Surgery Planning) model versus conventional CT for preoperative diagnosis of vascular involvement after neoadjuvant treatment (NAT) in patients with borderline or locally advanced PAC. This will be achieved by analyzing the accuracy variables of both techniques against the gold standard (surgical outcomes and histopathological analysis).</div></div>","PeriodicalId":50690,"journal":{"name":"Cirugia Espanola","volume":"104 2","pages":"Article 800256"},"PeriodicalIF":1.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145982099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01Epub Date: 2026-01-29DOI: 10.1016/j.ciresp.2025.800280
Carlos Cerdán-Santacruz , Matteo Frasson
{"title":"Manejo del cáncer de recto: el futuro ya es presente","authors":"Carlos Cerdán-Santacruz , Matteo Frasson","doi":"10.1016/j.ciresp.2025.800280","DOIUrl":"10.1016/j.ciresp.2025.800280","url":null,"abstract":"","PeriodicalId":50690,"journal":{"name":"Cirugia Espanola","volume":"104 2","pages":"Article 800280"},"PeriodicalIF":1.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146080002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Skin and nipple-sparing mastectomy with immediate reconstruction has become the standard treatment for women requiring a mastectomy. The objective of this article is to describe endoscopic mastectomy and analyze the initial results after its implementation in terms of care impact and post-surgical complications.
Methods
Preliminary results of the VideoBreast-24 in terms of safety and feasibility of the technique. VideoBreast-24 is a non-inferiority study that compares MPPP-E with immediate reconstruction with a polyurethane implant versus skin-sparing or skin-and-nipple mastectomy using the open technique performed within the framework of the PreQ-20 study.
Results
60 MPPP-E were performed on 42 women, 92.9% of whom were oncological patients. The average surgery time was 213.7 minutes. The average implant volume is 322cc, with the largest volume being 545cc. There were no implant losses.
Conclusions
Endoscopic mastectomy is a technique with a low incidence of postoperative complications, surgical reintervention and readmission. Surgical time is longer than that of open mastectomy, although it can be optimized 11 the learning curve has passed.
{"title":"Impacto asistencial y seguridad quirúrgica de la mastectomía endoscópica en mujeres con cáncer de mama y de alto riesgo. Resultados preliminares del estudio VideoBreast-24","authors":"Benigno Acea-Nebril, Alejandra García-Novoa, Sergio Sierra, Lucía Santos, Carmen Cereijo Garea","doi":"10.1016/j.ciresp.2026.800290","DOIUrl":"10.1016/j.ciresp.2026.800290","url":null,"abstract":"<div><h3>Introduction</h3><div>Skin and nipple-sparing mastectomy with immediate reconstruction has become the standard treatment for women requiring a mastectomy. The objective of this article is to describe endoscopic mastectomy and analyze the initial results after its implementation in terms of care impact and post-surgical complications.</div></div><div><h3>Methods</h3><div>Preliminary results of the VideoBreast-24 in terms of safety and feasibility of the technique. VideoBreast-24 is a non-inferiority study that compares MPPP-E with immediate reconstruction with a polyurethane implant versus skin-sparing or skin-and-nipple mastectomy using the open technique performed within the framework of the PreQ-20 study.</div></div><div><h3>Results</h3><div>60 MPPP-E were performed on 42 women, 92.9% of whom were oncological patients. The average surgery time was 213.7<!--> <!-->minutes. The average implant volume is 322cc, with the largest volume being 545cc. There were no implant losses.</div></div><div><h3>Conclusions</h3><div>Endoscopic mastectomy is a technique with a low incidence of postoperative complications, surgical reintervention and readmission. Surgical time is longer than that of open mastectomy, although it can be optimized 11<!--> <!-->the learning curve has passed.</div></div>","PeriodicalId":50690,"journal":{"name":"Cirugia Espanola","volume":"104 2","pages":"Article 800290"},"PeriodicalIF":1.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146174059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01Epub Date: 2026-01-28DOI: 10.1016/j.ciresp.2025.800279
Marcos Bruna , María Asunción Acosta , Silvia Carbonell , Luis Gómez , Marian Mayo , Salvador Morales-Conde , Aitana Garcia-Tejero , Silvia Aguas , David Ruíz de Angulo , Vicente Munitiz , Luisa Martínez de Haro , Vanessa Concepción , Fernando Mingol , Miriam Menéndez , Gabriel Salcedo , Esteban Martín , Ana Senent , Alexis Luna , Dulce Momblán , Pablo Priego , Mónica Miró
Hiatal hernia (HH) is a relatively prevalent condition in our setting, yet there is little clinical evidence or guidelines establishing precise recommendations for its diagnostic and therapeutic management.
In order to establish clinical recommendations for the diagnostic and therapeutic management of patients with complex hiatal hernia, defined as a primary type III or IV mixed hernia, a large one with >30% of the gastric contents in the thoracic cavity, or a recurrence. This document was prepared based on current scientific evidence and the experience of a group of 28 expert surgeons, using GRADE methodology in order to establish recommendations on 13 controversial aspects related to this pathology.
Although the quality of evidence and the degree of recommendation are high in some areas, high-quality prospective clinical studies are needed to clarify certain unresolved points of controversy.
{"title":"Hernias de hiato complejas. Recomendaciones de manejo diagnóstico y terapéutico","authors":"Marcos Bruna , María Asunción Acosta , Silvia Carbonell , Luis Gómez , Marian Mayo , Salvador Morales-Conde , Aitana Garcia-Tejero , Silvia Aguas , David Ruíz de Angulo , Vicente Munitiz , Luisa Martínez de Haro , Vanessa Concepción , Fernando Mingol , Miriam Menéndez , Gabriel Salcedo , Esteban Martín , Ana Senent , Alexis Luna , Dulce Momblán , Pablo Priego , Mónica Miró","doi":"10.1016/j.ciresp.2025.800279","DOIUrl":"10.1016/j.ciresp.2025.800279","url":null,"abstract":"<div><div>Hiatal hernia (HH) is a relatively prevalent condition in our setting, yet there is little clinical evidence or guidelines establishing precise recommendations for its diagnostic and therapeutic management.</div><div>In order to establish clinical recommendations for the diagnostic and therapeutic management of patients with complex hiatal hernia, defined as a primary type III or IV mixed hernia, a large one with<!--> <!-->>30% of the gastric contents in the thoracic cavity, or a recurrence. This document was prepared based on current scientific evidence and the experience of a group of 28 expert surgeons, using GRADE methodology in order to establish recommendations on 13 controversial aspects related to this pathology.</div><div>Although the quality of evidence and the degree of recommendation are high in some areas, high-quality prospective clinical studies are needed to clarify certain unresolved points of controversy.</div></div>","PeriodicalId":50690,"journal":{"name":"Cirugia Espanola","volume":"104 2","pages":"Article 800279"},"PeriodicalIF":1.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146080001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01Epub Date: 2026-01-15DOI: 10.1016/j.ciresp.2025.800270
Andrea Boscà Robledo , Eva M. Montalvá Orón , Ana Navío Seller , Javier Maupoey Ibáñez , Ana Hernando Sanz , David Calatayud Mizrahi , Francisco J. Orbis Castellanos , Rafael López Andújar
Background
There is abundant scientific literature on the use of haemostatics and sealants in liver surgery, but there is a lack of evidence due to the difficulty to apply adequate methodologies without conflicts of interest.
This prospective randomized study with the main objective is to determine the efficacy of the local haemostatic Hemopatch® in the incidence of bleeding and biliary fistula in patients undergoing elective liver resection.
Methods
This was a single-center study where 222 patients were analyzed: 115 patients had been randomized to the control group and 107 to the experimental group. The patients after liver resection are randomized to place Hemopatch® or not on the transection liver surface. Patients with all types of liver resections and with laparotomic and laparoscopic approaches were included. During postoperative follow-up, an abdominal drain is placed, and hemoglobin and bilirubin are analyzed during the first three days.
Results
Clinically postoperative bleeding occurred in 3.5% of the patients in the control group and in 2.8% of the experimental group (P = .409). The incidence of postoperative biliary fistula was 17.4% in the control group and 23.4% in the experimental group (P = .269). There were also no differences in the rest of the parameters analyzed.
Conclusions
The results on the use of Hemopatch® in liver resection to prevent hemorrhage and biliary fistula are inconclusive. It cannot be routinely recommended and surgeons should be more demanding with the scientific evidence to justify the systematic use of haemostatics agents.
{"title":"Evidencia clínica del uso de Hemopatch® en la reducción del sangrado y fístula biliar tras resección hepática. Estudio prospectivo aleatorizado en cirugía programada","authors":"Andrea Boscà Robledo , Eva M. Montalvá Orón , Ana Navío Seller , Javier Maupoey Ibáñez , Ana Hernando Sanz , David Calatayud Mizrahi , Francisco J. Orbis Castellanos , Rafael López Andújar","doi":"10.1016/j.ciresp.2025.800270","DOIUrl":"10.1016/j.ciresp.2025.800270","url":null,"abstract":"<div><h3>Background</h3><div>There is abundant scientific literature on the use of haemostatics and sealants in liver surgery, but there is a lack of evidence due to the difficulty to apply adequate methodologies without conflicts of interest.</div><div>This prospective randomized study with the main objective is to determine the efficacy of the local haemostatic Hemopatch® in the incidence of bleeding and biliary fistula in patients undergoing elective liver resection.</div></div><div><h3>Methods</h3><div>This was a single-center study where 222 patients were analyzed: 115 patients had been randomized to the control group and 107 to the experimental group. The patients after liver resection are randomized to place Hemopatch® or not on the transection liver surface. Patients with all types of liver resections and with laparotomic and laparoscopic approaches were included. During postoperative follow-up, an abdominal drain is placed, and hemoglobin and bilirubin are analyzed during the first three days.</div></div><div><h3>Results</h3><div>Clinically postoperative bleeding occurred in 3.5% of the patients in the control group and in 2.8% of the experimental group (<em>P</em> <!-->=<!--> <!-->.409). The incidence of postoperative biliary fistula was 17.4% in the control group and 23.4% in the experimental group (<em>P</em> <!-->=<!--> <!-->.269). There were also no differences in the rest of the parameters analyzed.</div></div><div><h3>Conclusions</h3><div>The results on the use of Hemopatch® in liver resection to prevent hemorrhage and biliary fistula are inconclusive. It cannot be routinely recommended and surgeons should be more demanding with the scientific evidence to justify the systematic use of haemostatics agents.</div></div>","PeriodicalId":50690,"journal":{"name":"Cirugia Espanola","volume":"104 2","pages":"Article 800270"},"PeriodicalIF":1.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145982101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01Epub Date: 2026-01-16DOI: 10.1016/j.ciresp.2025.800249
Juli Busquets , Núria Peláez , Luis Secanella , Maria Sorribas , Elena Iborra
The resection of locally advanced adenocarcinoma of the pancreatic head with occlusion of the superior mesenteric vein and involvement of the splenomesentericportal confluent (EMP) sometimes requires prolonged venous clamping with risk of intestinal ischemia. The use of intraoperative venous shunts has been published by reference groups to allow successful resection. In our center we performed a total pancreatoduodenectomy for locally advanced pancreatic head adenocarcinoma with superior mesenteric vein occlusion (SMV) and splenomesentericportal confluent. The use of a transient ileo-caval shunt via a venous graft allowed resection of the tumor without repercussion on the bowel. The surgery ended with closure of the shunt, anastomosis of the graft to the portal vein and digestive reconstruction. The patient presented good tolerance to surgery and was discharged on the 7 th postoperative day. The pathology report described pancreatic adenocarcinoma ypT1N0(R0) regression grade GRT2/IIa, with 0/30 affected adenopathies.
{"title":"Shunt íleo-cava intraoperatorio transitorio en la resección de adenocarcinoma de cabeza de páncreas localmente avanzado: ¿rompiendo un techo?","authors":"Juli Busquets , Núria Peláez , Luis Secanella , Maria Sorribas , Elena Iborra","doi":"10.1016/j.ciresp.2025.800249","DOIUrl":"10.1016/j.ciresp.2025.800249","url":null,"abstract":"<div><div>The resection of locally advanced adenocarcinoma of the pancreatic head with occlusion of the superior mesenteric vein and involvement of the splenomesentericportal confluent (EMP) sometimes requires prolonged venous clamping with risk of intestinal ischemia. The use of intraoperative venous <em>shunt</em>s has been published by reference groups to allow successful resection. In our center we performed a total pancreatoduodenectomy for locally advanced pancreatic head adenocarcinoma with superior mesenteric vein occlusion (SMV) and splenomesentericportal confluent. The use of a transient ileo-caval <em>shunt</em> via a venous graft allowed resection of the tumor without repercussion on the bowel. The surgery ended with closure of the <em>shunt</em>, anastomosis of the graft to the portal vein and digestive reconstruction. The patient presented good tolerance to surgery and was discharged on the 7<!--> <!-->th postoperative day. The pathology report described pancreatic adenocarcinoma ypT1N0(R0) regression grade GRT2/IIa, with 0/30 affected adenopathies.</div></div>","PeriodicalId":50690,"journal":{"name":"Cirugia Espanola","volume":"104 2","pages":"Article 800249"},"PeriodicalIF":1.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145982102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01Epub Date: 2026-01-28DOI: 10.1016/j.ciresp.2025.800254
Paula Jimenez-Fonseca , Marcos Bruna , Javier Gallego , Mónica Miró , Mireia Gil , Fernando Pereira , Gema Marín , Delia Cortés , Roberto Pazo , Mariagiulia Dal Cero , Elena Martín , Fernando Rivera
This manuscript presents a systematic review and expert consensus from oncology and surgery on the management of metastatic gastric cancer. A literature search was conducted in PubMed and Google Scholar, selecting 28 relevant studies (21 clinical trials and 7 systematic reviews), along with international guidelines. The objective was to assess the role of surgery and locoregional therapies in patients with peritoneal, hepatic, pulmonary, or nodal metastases, and to establish multidisciplinary recommendations. Cytoreductive surgery associated to HIPEC may offer benefits in selected patients with limited peritoneal carcinomatosis (Peritoneal Carcinomatosis Index ≤6), an absence of distant metastasis, an adequate response to systemic chemotherapy and an ECOG performance status of 0-1. Resection of non-peritoneal metastases may also be considered in specific contexts. Prospective clinical trials are required to confirm these findings and define optimal selection criteria.
{"title":"Manejo quirúrgico del adenocarcinoma gástrico estadio IV: revisión sistemática y recomendaciones del Grupo de Tratamiento de los Tumores Digestivos y la Asociación Española de Cirujanos","authors":"Paula Jimenez-Fonseca , Marcos Bruna , Javier Gallego , Mónica Miró , Mireia Gil , Fernando Pereira , Gema Marín , Delia Cortés , Roberto Pazo , Mariagiulia Dal Cero , Elena Martín , Fernando Rivera","doi":"10.1016/j.ciresp.2025.800254","DOIUrl":"10.1016/j.ciresp.2025.800254","url":null,"abstract":"<div><div>This manuscript presents a systematic review and expert consensus from oncology and surgery on the management of metastatic gastric cancer. A literature search was conducted in PubMed and Google Scholar, selecting 28 relevant studies (21 clinical trials and 7 systematic reviews), along with international guidelines. The objective was to assess the role of surgery and locoregional therapies in patients with peritoneal, hepatic, pulmonary, or nodal metastases, and to establish multidisciplinary recommendations. Cytoreductive surgery associated to HIPEC may offer benefits in selected patients with limited peritoneal carcinomatosis (Peritoneal Carcinomatosis Index ≤6), an absence of distant metastasis, an adequate response to systemic chemotherapy and an ECOG performance status of 0-1. Resection of non-peritoneal metastases may also be considered in specific contexts. Prospective clinical trials are required to confirm these findings and define optimal selection criteria.</div></div>","PeriodicalId":50690,"journal":{"name":"Cirugia Espanola","volume":"104 2","pages":"Article 800254"},"PeriodicalIF":1.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146080000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}