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Managing a Patient with Pulmonary Thromboembolic Disease Presenting with Active Hemoptysis: A Case Report 处理一名出现活动性咯血的肺血栓栓塞症患者:病例报告
Pub Date : 2024-07-18 DOI: 10.1093/ehjcr/ytae353
Moon-Kyung Jung, Hwan Wook Kim, K. S. Beck, Y. Sung, M. Jung
Pulmonary thromboembolism and active hemoptysis represent distinct yet critical emergencies necessitating immediate intervention. However, the treatment protocols for these conditions—anticoagulation therapy and hemostatic therapy—often pose a dilemma. We present the case of a 25-year-old female who presented to our emergency room with hemoptysis and a concurrent diagnosis of pulmonary thromboembolism. Due to persistent active hemoptysis, we temporarily paused anticoagulation and opted for surgical pulmonary thrombectomy, enabling the safe resumption of anticoagulation therapy. Hemoptysis occurring in pulmonary thromboembolism is infrequently reported in the literature, and established treatment guidelines for such cases are lacking. This case could provide guidance on how to handle the intricate treatment challenges posed by concurrent hemoptysis and pulmonary thromboembolism.
肺血栓栓塞症和活动性咯血是截然不同的危急情况,必须立即进行干预。然而,这两种疾病的治疗方案--抗凝疗法和止血疗法--往往让人进退两难。 我们介绍了一例 25 岁女性患者的病例,她因咯血来到我们的急诊室,同时被诊断为肺血栓栓塞症。由于咯血持续活跃,我们暂时停止了抗凝治疗,并选择了外科肺血栓切除术,从而安全地恢复了抗凝治疗。 肺血栓栓塞症引起的咯血在文献中鲜有报道,也缺乏针对此类病例的既定治疗指南。本病例可为如何应对并发咯血和肺血栓栓塞症带来的复杂治疗难题提供指导。
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引用次数: 0
Long Story Short 长话短说
Pub Date : 2024-07-18 DOI: 10.1093/ehjcr/ytae351
M. Almasri, Nirbhay Parashar, J. Orcutt
In this manuscript, we present an ECG that is diagnostic of short QT syndrome and ask questions regarding arrhythmia risk and possible complications regarding management.
在本手稿中,我们展示了一张可诊断为短 QT 综合征的心电图,并提出了有关心律失常风险和治疗方面可能出现的并发症的问题。
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引用次数: 0
Which prophylaxis is senseful after contrast-induced DRESS? The role of double prophylaxis and chemical cross-reactivity 造影剂诱导的 DRESS 后,哪种预防措施更有意义?双重预防和化学交叉反应的作用
Pub Date : 2024-07-18 DOI: 10.1093/ehjcr/ytae352
Ingrid B Boehm
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引用次数: 0
Takayasu Arteritis Manifesting as Acute Kidney Injury and Congestion Due to Renal-Artery Stenosis and Myocarditis: A Case Report 因肾动脉狭窄和心肌炎而表现为急性肾损伤和充血的高安市动脉炎:病例报告
Pub Date : 2024-07-18 DOI: 10.1093/ehjcr/ytae347
Misato Hara, Shintaro Mandai, Takayasu Mori, Yasuhiro Maejima, Shinichi Uchida
Takayasu arteritis is a large vessel vasculitis that affects the aorta and its primary branches. Myocarditis is a rare life-threatening complication and potential diagnostic pitfall in patients with Takayasu arteritis. A previously healthy 18-year-old woman presenting with fever, back pain, and dyspnea was admitted to another hospital for acute hypertension (blood pressure, 230/106 mmHg) and congestive heart failure. Intravenous methylprednisolone pulse with antihypertensive and diuretic medications slightly improved her congestion. However, she developed acute kidney injury and was transferred to our hospital. Transthoracic echocardiography indicated a left ventricular ejection fraction of 45% and diffuse left ventricular hypokinesis. Doppler ultrasound test and magnetic resonance angiography revealed severe bilateral renal-artery stenosis. Her diagnosis was Takayasu arteritis and she received high-dose glucocorticoids. She required temporary hemodialysis, but two months after admission, her serum creatinine improved to 1.1 mg/dL without surgical/cardiovascular interventions. Although the pre-discharge test with 1.5- Tesla cardiac magnetic resonance initially failed to diagnose myocarditis, 3-Tesla cardiac magnetic resonance imaging revealed increased native T1 values on T1 mapping (1283–1393 ms), moderate pericardial effusion, and systolic left ventricular wall motion abnormality, indicating active myocarditis. During 6-month subcutaneous tocilizumab treatment (162 mg/week), a left ventricular ejection fraction improved to 55–60% without a relapse. This case report highlights the benefits of early multimodal imaging tests including cardiac magnetic resonance imaging for myocarditis and renal artery involvement in Takayasu arteritis. Tocilizumab might be an efficient therapeutic option for severe acute manifestations including myocarditis in young women of reproductive age.
高安动脉炎是一种影响主动脉及其主要分支的大血管脉管炎。心肌炎是一种罕见的危及生命的并发症,也是高安动脉炎患者潜在的诊断陷阱。 一名之前身体健康的 18 岁女性因发热、背痛和呼吸困难被另一家医院收治,原因是急性高血压(血压 230/106 mmHg)和充血性心力衰竭。静脉注射甲基强的松龙脉冲,同时服用降压药和利尿药,稍微改善了她的充血症状。然而,她出现了急性肾损伤,被转到我院。经胸超声心动图显示,她的左心室射血分数为 45%,左心室弥漫性运动功能减退。多普勒超声检查和磁共振血管造影显示双侧肾动脉严重狭窄。她被诊断为高安动脉炎,并接受了大剂量糖皮质激素治疗。她需要暂时进行血液透析,但入院两个月后,她的血清肌酐降至 1.1 mg/dL,且未进行外科/心血管干预。虽然出院前的 1.5 特斯拉心脏磁共振检查最初未能诊断出心肌炎,但 3 特斯拉心脏磁共振成像显示 T1 映射(1283-1393 毫秒)的原生 T1 值增高、中度心包积液和收缩期左心室壁运动异常,表明心肌炎正在活动。在为期 6 个月的皮下注射托西珠单抗治疗(162 毫克/周)期间,左心室射血分数改善至 55-60%,且未复发。 本病例报告强调了早期多模态成像检查(包括心脏磁共振成像)对心肌炎和高安动脉炎肾动脉受累的益处。对于育龄年轻女性的严重急性表现,包括心肌炎,托珠单抗可能是一种有效的治疗选择。
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引用次数: 0
The elephant trunk: A rare morphology of the left atrial appendage – a case report 大象的树干左心房阑尾的罕见形态--病例报告
Pub Date : 2024-07-18 DOI: 10.1093/ehjcr/ytae334
P. Fischer, F. Mahfoud, M. Böhm, Christian Ukena
Patients with atrial fibrillation (AF) are at increased risk for thromboembolic events including stroke. The primary source for thromboembolism in these patients is thrombus formation in the left atrial appendage (LAA). Depending on the individual thromboembolic risk, long-term anticoagulation is recommended. In certain patients however, long-term anticoagulation is contraindicated and interventional closure of the LAA (LAAC) represents an alternative approach to lower the thromboembolic risk and avoid oral anticoagulation. An 83-year-old male underwent LAAC at our center in November 2022. Prior to the procedure, a thrombus in the left atrium (LA) or LAA was excluded by transoesophageal echocardiography (TOE) and the anatomy of the LAA was assessed as eligible for LAAC with no evidence of anatomical irregularities. After contrast medium injection, angiography revealed an atypical anatomic variant of the LAA with a substantially long, elephant-trunk-like course. We present a previously not described unique anatomic variant of the LAA: the elephant trunk morphology. LAA anatomy is very heterogeneous and detailed knowledge of LAA morphology is important for endovascular LAA procedures as well as for predicting the risk of thromboembolic events. Despite thorough preprocedural imaging, anatomic variants may remain obscured.
心房颤动(房颤)患者发生血栓栓塞事件(包括中风)的风险增加。这些患者血栓栓塞的主要来源是左心房附壁(LAA)血栓的形成。根据个人血栓栓塞风险的不同,建议进行长期抗凝治疗。但在某些患者中,长期抗凝是禁忌的,而介入性关闭 LAA(LAAC)是降低血栓栓塞风险和避免口服抗凝药的另一种方法。 一名 83 岁的男性于 2022 年 11 月在本中心接受了 LAAC 手术。术前,经食道超声心动图(TOE)排除了左心房(LA)或LAA内的血栓,并对LAA的解剖结构进行了评估,认为其符合LAAC的要求,且无解剖结构不规则的证据。注射造影剂后,血管造影显示 LAA 存在非典型解剖变异,其走向呈大象茎状,非常长。 我们介绍了一种以前从未描述过的 LAA 独特解剖变异:象鼻形态。LAA 的解剖结构千差万别,详细了解 LAA 形态对于血管内 LAA 手术以及预测血栓栓塞事件的风险非常重要。尽管进行了彻底的术前成像,但解剖变异可能仍然不明显。
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引用次数: 0
Very Late Magmaris Scaffold Restenosis: A 6-year Serial Optical Coherence Tomography Case Report 极晚期 Magmaris 支架再狭窄:6 年连续光学相干断层扫描病例报告
Pub Date : 2024-07-17 DOI: 10.1093/ehjcr/ytae344
Jens Trøan, K. Hansen, Manijeh Noori, J. Lassen, L. O. Jensen
Bioresorbable scaffolds (BRS) have been proposed as an alternative to drug-eluting stents (DES), offering radial support during the early phases of healing, while potentially reducing the risk of long-term complications. A magnesium-based BRS (MgBRS) have shown promising results after implantation. However, there is a lack of knowledge regarding the long-term outcomes. A 62-year old man with hypertension, dyslipidemia, family history of ischemic heart disease, and previous myocardial infarction, presented with Non ST-elevation myocardial infarction (NSTEMI). Six years prior he also had a NSTEMI and a mid left anterior descending artery (LAD) lesion was treated with a 3.0/25mm MgBRS. Post-implantation optical coherence tomography (OCT) revealed proximal edge dissection, and a second MgBRS 3.0/15mm was implanted. OCT of the scaffold-treated segment was performed after 6 and 12 months with no sign of restenosis. The current angiogram showed a restenosis in the previously MgBRS treated segment in LAD. OCT showed a plaque rupture in a thin cap fibro-atheroma and scaffold remnants. The lesion was pre-dilated and stented with a 3.0/20mm DES and post-dilated with a 3.5mm non-compliant balloon. Most cases of late scaffold failure showed acquired malapposition, which also can be related to the degrading process, or uncovered struts, none of which were seen in our case at 6 or 12 months. This case represents an insight into the vascular healing and potential mechanisms for failure of the MgBRS, with serial OCT recording at implantation, and after 6 months, 12 months and 6 years.
生物可吸收支架(BRS)被建议作为药物洗脱支架(DES)的替代品,在愈合的早期阶段提供径向支撑,同时可能降低长期并发症的风险。镁基 BRS(MgBRS)在植入后显示出良好的效果。然而,人们对其长期疗效还缺乏了解。 一名 62 岁的男性患者患有高血压、血脂异常、缺血性心脏病家族史和既往心肌梗死,并出现非 ST 段抬高型心肌梗死(NSTEMI)。六年前,他也曾患过一次非 STEMI,并用 3.0/25 毫米 MgBRS 治疗了左前降支动脉(LAD)中段病变。植入后的光学相干断层扫描(OCT)显示近端边缘剥离,于是植入了第二个 3.0/15 毫米 MgBRS。6 个月和 12 个月后,对支架处理过的部分进行了光学相干断层扫描,未发现再狭窄迹象。目前的血管造影显示,之前接受过 MgBRS 治疗的 LAD 段出现了再狭窄。OCT 显示薄帽纤维血管瘤斑块破裂,支架残余。使用 3.0/20 毫米 DES 对病变进行预扩张和支架植入,并使用 3.5 毫米非顺应性球囊进行后扩张。 大多数支架晚期失败的病例都表现为获得性贴壁不良,这也可能与降解过程或未覆盖的支架有关,而我们的病例在6个月或12个月时都没有出现这种情况。本病例通过植入时、6 个月后、12 个月后和 6 年后的连续 OCT 记录,深入了解了 MgBRS 的血管愈合和潜在失效机制。
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引用次数: 0
CardioTwins: Case report of a transcatheter mitral and tricuspid valve implantation in one patient CardioTwins:一名患者经导管二尖瓣和三尖瓣植入术的病例报告
Pub Date : 2024-07-17 DOI: 10.1093/ehjcr/ytae336
T. Schmidt, Karl-Heinz Kuck, C. Marquetand, Ingo Eitel, C. Frerker
Besides transcatheter edge-to-edge repair (TEER) there are new interventional treatment options for mitral and tricuspid regurgitation in evaluation, such as a complete replacement of the valve through a prosthesis. A 78-years-old previous coronary artery bypass graft-operated patient with symptomatic severe mitral regurgitation and tricuspid regurgitation was sequentially treated by a transfemoral transcatheter mitral and tricuspid valve prosthesis (Cardiovalve; Cardiovalve Ltd, Israel) due to unfavorable mitral valve anatomy. The transcatheter mitral valve implantation (TMVI) was performed first and after progression of the tricuspid regurgitation, a second transcatheter valve prosthesis was implanted in tricuspid position (TTVI) 1.5 years later. Imaging showed a twin look-alike picture of a mitral and tricuspid prosthesis and showing the possibility of a complete transcatheter based replacement of the mitral and tricuspid valve. This case shows the possibility of a Cardiovalve prosthesis being used for TMVI and TTVI in a single patient. Especially in TEER ineligible patients it might be a good treatment option after device approval. A Cardiovalve prothesis can be used for TMVI and TTVI, especially in TEER ineligible patients and with one device for both anatomies, which might be a good treatment option after device approval.
除了经导管边缘到边缘修补术(TEER)外,二尖瓣和三尖瓣反流还有新的介入治疗方案正在评估中,如通过假体完全置换瓣膜。 一位 78 岁的患者曾接受过冠状动脉旁路移植手术,患有无症状的严重二尖瓣返流和三尖瓣返流,由于二尖瓣解剖结构不佳,他先后接受了经导管二尖瓣和三尖瓣人工瓣膜(Cardiovalve;以色列 Cardiovalve 有限公司)治疗。首先进行了经导管二尖瓣植入术(TMVI),在三尖瓣反流进展后,1.5年后在三尖瓣位置植入了第二个经导管瓣膜。成像显示二尖瓣和三尖瓣假体的外观相似,显示了经导管完全置换二尖瓣和三尖瓣的可能性。 该病例显示了将 Cardiovalve 人工瓣膜用于单个患者的 TMVI 和 TTVI 的可能性。特别是对于不符合 TEER 条件的患者,在设备获得批准后,这可能是一种很好的治疗选择。 Cardiovalve 人工瓣膜可用于 TMVI 和 TTVI,尤其是对于不符合 TEER 条件的患者,而且只需一种设备即可同时用于两种解剖结构,这可能是设备获得批准后的一种良好治疗选择。
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引用次数: 0
A Case Report Of Cardiac Tamponade After A Road Accident: Think Beyond Trauma 交通事故后心脏填塞的病例报告:超越创伤
Pub Date : 2024-07-16 DOI: 10.1093/ehjcr/ytae324
Giovanni Civieri, Davide Betta, Carlo Cernetti, N. Gasparetto
Cardiac tamponade is a life-threatening compression of the heart caused by the accumulation of fluid in the pericardial sac. Although central venous catheters (CVCs) are essential in modern medicine, they carry a certain risk of complications including cardiac tamponade. A 12 year-old female was involved in a road accident reporting multiple severe traumatic injuries, including a left humerus fracture and subdural hemorrhage. After 2 days in the intensive care unit, she suddenly developed hypotension and cardiac tamponade was diagnosed. Analysis of the pericardial fluid showed high glucose levels comparable to the parenteral nutrition that she was receiving. Retraction of the CVC allowed resolution of the effusion. Cardiac tamponade is a rare but serious adverse event after CVCs insertion, mostly among younger patients. Awareness of this risk allows physicians to promptly recognize and treat this dangerous complication.
心脏填塞是心包积液导致的心脏压迫,会危及生命。虽然中心静脉导管(CVC)在现代医学中必不可少,但它也有一定的并发症风险,包括心脏填塞。 一名 12 岁的女性在一次交通事故中多处严重受伤,包括左肱骨骨折和硬膜下出血。在重症监护室住了两天后,她突然出现低血压,被诊断为心脏填塞。对心包积液的分析表明,葡萄糖水平较高,与她接受的肠外营养相当。回缩 CVC 后,积液得以消退。 心脏填塞是插入 CVC 后发生的一种罕见但严重的不良事件,主要发生在年轻患者身上。认识到这一风险后,医生就能及时发现并治疗这种危险的并发症。
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引用次数: 0
Transcatheter edge-to-edge repair of both atrio-ventricular valves in congenitally corrected transposition of the great arteries: a case report 先天性大动脉转位矫正术中两个寰室瓣的经导管边缘对边缘修补术:病例报告
Pub Date : 2024-07-16 DOI: 10.1093/ehjcr/ytae348
A. Patrascu, D. Binder, Peter Schnabel, K. Weinmann, I. Ott
Transcatheter edge-to-edge repair (TEER) for the systemic atrioventricular valve has been anecdotally reported as a viable treatment option in symptomatic inoperable adult patients born with congenitally corrected transposition of the great arteries (ccTGA) . However, to date, case reports on TEER treatment of both atrioventricular valves are lacking, especially when considering the present availability of specific mitral and tricuspid valve TEER devices. We present the case of an 84-year-old man with recurrent admissions for acute heart failure due to high-grade regurgitation of both atrioventricular valves. The patient was first diagnosed with ccTGA at this advanced age and underwent a thorough multimodality imaging approach, including transthoracic and transesophageal echocardiography, cardiac MRI, cardiac CT, and ventriculography of the systemic ventricle. Due to the high symptom burden despite optimal medical therapy and high doses of diuretics, the Heart Team recommended TEER, first for the systemic tricuspid valve, and later on for the non-sytemic mitral valve. Both complex procedures were uneventful and led to considerable improvement in quality of life. ccTGA mostly manifests itself in adulthood and affects both ventricles and atrioventricular valves. In case of anatomical doubts on transthoracic echocardiography, a thorough multimodality imaging work-up is recommended. Transcatheter treatment of both atrioventricular valves seems to be a safe and effective therapeutic option in these often-inoperable patients.
对于患有先天性矫正性大动脉转位(ccTGA)、无症状、无法手术的成年患者,经导管边缘到边缘修补术(TEER)治疗系统性房室瓣是一种可行的治疗方法。然而,迄今为止,还缺乏关于两个房室瓣 TEER 治疗的病例报告,特别是考虑到目前已有特定的二尖瓣和三尖瓣 TEER 装置。 我们介绍了一名 84 岁男性患者的病例,他因两个房室瓣高度反流而反复因急性心力衰竭入院。患者在高龄时首次被诊断为ccTGA,并接受了全面的多模式成像检查,包括经胸和经食道超声心动图、心脏核磁共振成像、心脏CT和系统性心室的心室造影。尽管采用了最佳的药物治疗和大剂量的利尿剂,但患者的症状仍然很重,因此心脏团队建议患者接受 TEER 手术,首先是系统性三尖瓣手术,随后是非淤血性二尖瓣手术。这两项复杂的手术都很顺利,并大大改善了患者的生活质量。ccTGA 大多在成年后出现,影响心室和房室瓣。如果对经胸超声心动图的解剖结构存在疑问,建议进行全面的多模态成像检查。对于这些经常无法手术的患者来说,经导管治疗两个房室瓣似乎是一种安全有效的治疗方法。
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引用次数: 0
Wide QRS Tachycardia in a Patient with Atrial Fibrillation: A Case Report and Approach to Diagnosis 心房颤动患者的宽 QRS 心动过速:病例报告和诊断方法
Pub Date : 2024-07-15 DOI: 10.1093/ehjcr/ytae328
Mohammad Shaikh, Hafez Golzarian, F. Hakim
Wide QRS tachycardia in patients with atrial fibrillation or atrial flutter treated with antiarrhythmic drugs can occur for a variety of reasons and needs careful evaluation for appropriate management of the patient. We report a case of wide QRS complex tachycardia in a patient with atrial fibrillation treated with Flecainide who received multiple external cardioversion attempts for a presumed diagnosis of ventricular tachycardia. Intravenous Diltiazem and an oral beta blocker led to the resolution of wide QRS complex tachycardia. Wide QRS tachycardia due to pro-arrhythmic effect or rate dependency phenomenon of antiarrhythmic agents should be included in the differentials. In this brief report, we discuss the differential diagnosis and outline a practical approach for acute and long-term management of these patients.
接受抗心律失常药物治疗的心房颤动或心房扑动患者出现宽 QRS 期心动过速的原因多种多样,需要对患者进行仔细评估以采取适当的治疗措施。 我们报告了一例使用氟卡尼治疗的心房颤动患者出现宽 QRS 波群心动过速的病例,该患者曾因假定诊断为室性心动过速而多次尝试体外心脏除颤。静脉注射地尔硫卓和口服β受体阻滞剂后,宽 QRS 波群心动过速得到缓解。 由于抗心律失常药物的促心律失常作用或心率依赖现象导致的宽 QRS 心动过速应列入鉴别诊断。在这份简短的报告中,我们讨论了鉴别诊断,并概述了对这些患者进行急性和长期管理的实用方法。
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引用次数: 0
期刊
European Heart Journal - Case Reports
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